Hub : Genes

Tctn3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Tctn3 0.04 0.03 2.9e-05 0.03 0.03 0.03 0.04 1.0e-04 2.7e-04 1.5e-04 4.1e-05
2 Adipose gene expression Tctn3 0.12 0.05 2.7e-12 0.07 0.07 0.06 0.07 1.7e-08 1.5e-08 3.6e-07 1.8e-08
3 LHb gene expression Tctn3 0.15 0.09 2.7e-03 0.13 0.1 0.09 0.11 5.8e-04 2.8e-03 3.3e-03 1.7e-03
4 Brain mRNA stability Tctn3 0.03 0.02 1.9e-03 0.02 0.02 0.01 0.02 4.0e-03 3.2e-03 2.7e-02 4.9e-03
5 BLA gene expression Tctn3 0.23 0.11 3.5e-11 0.19 0.21 0.2 0.2 2.3e-10 2.6e-11 7.9e-11 5.7e-11
6 PL gene expression Tctn3 0.15 0.08 8.6e-11 0.09 0.11 0.12 0.11 3.4e-10 8.8e-12 8.3e-13 2.8e-12
7 Brain gene expression Tctn3 0.09 0.05 3.6e-08 0.07 0.07 0.08 0.07 2.1e-07 3.3e-07 3.6e-08 3.0e-07
8 pVTA gene expression Tctn3 0.09 0.06 7.0e-04 0.07 0.06 0.05 0.06 4.3e-04 8.6e-04 2.8e-03 1.4e-03
9 IL gene expression Tctn3 0.15 0.1 1.9e-03 0.1 0.1 0.09 0.07 2.5e-03 1.9e-03 3.3e-03 8.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.50.91.7-1.3-0.70.81.0-0.90.51.10.8-1.1
Area under the delay curve1.31.42.81.11.7-1.3-1.21.3-1.5-0.5-0.90.5
BMI with tail0.82.53.5-1.9-1.81.91.8-1.71.00.91.7-1.0
BMI without tail1.32.83.8-1.9-1.81.91.8-1.81.31.51.4-1.3
Body weight0.52.04.3-1.5-2.11.41.5-1.61.60.51.1-0.5
Weight adjusted by age0.20.20.9-1.0-0.50.50.5-0.40.2-0.20.3-0.0
Bone surface1.72.94.3-1.8-1.31.51.7-1.71.22.11.9-1.9
Bone volume1.72.83.5-1.8-1.51.61.8-1.71.41.91.7-1.7
Breakpoint value in progressive ratio session0.50.61.61.30.6-0.9-0.80.7-0.4-0.7-0.30.7
Number of licking bursts2.53.05.21.42.0-1.8-1.71.8-2.3-1.5-1.41.4
Context. condit. distance diff. score0.30.41.0-0.5-1.00.60.5-0.60.6-0.50.60.1
Locomotion velocity, session 15.66.08.72.32.9-2.5-2.62.7-2.9-1.9-2.21.9
Locomotion distance, session 11.51.93.11.41.8-1.5-1.51.6-1.6-0.9-0.81.1
Locomotion velocity, session 20.81.02.61.01.6-1.2-0.91.0-1.20.5-0.4-0.2
Locomotion distance, session 20.71.02.10.81.4-0.9-1.11.2-1.4-0.4-0.70.7
Locomotion velocity, session 30.00.10.10.40.0-0.1-0.20.10.3-0.40.10.2
Locomotion distance, session 30.30.31.70.2-0.90.40.3-0.51.30.10.3-0.1
Stereotopy head waving bouts, day 30.30.30.70.60.4-0.6-0.60.6-0.5-0.7-0.30.8
Stereotopy head waving duration, day 30.40.50.80.60.7-0.7-0.70.7-0.9-0.8-0.50.9
Locomotion velocity, session 70.70.81.2-0.8-0.81.10.8-0.81.00.90.7-0.9
Locomotion distance, session 70.81.01.7-1.0-0.81.31.0-1.01.01.10.5-1.0
Stereotopy head waving bouts, day 72.32.64.12.01.3-1.8-1.71.6-1.4-1.9-0.51.8
Stereotopy head waving duration, day 70.60.71.31.10.5-0.9-0.80.7-0.6-1.10.31.0
Locomotion velocity, session 80.10.10.60.30.0-0.3-0.10.1-0.0-0.30.70.1
Locomotion distance, session 80.10.10.40.10.1-0.1-0.30.3-0.4-0.7-0.00.6
Degree of sensitization distance0.30.31.1-0.20.7-0.2-0.30.4-1.0-0.0-0.80.2
Degree of sensitization stereotypy1.82.03.51.81.0-1.5-1.51.4-1.1-1.9-0.11.6
Conditioned locomotion1.61.93.4-1.5-1.91.41.5-1.51.30.71.5-0.7
Cocaine response after cond. corrected0.20.20.40.30.5-0.6-0.40.4-0.6-0.4-0.50.4
Cocaine response after cond. not corrected0.40.51.10.70.7-0.9-0.70.7-0.5-0.4-1.00.5
Cocaine response before conditioning0.81.02.31.31.1-0.9-1.11.0-0.4-0.6-1.50.6
Saline control response1.92.53.71.91.2-1.7-1.71.6-1.2-1.9-0.71.9
Bone: connectivity density2.13.35.7-2.2-1.11.61.8-1.70.92.41.8-2.3
Bone: cortical apparent density2.63.54.61.51.8-1.9-1.81.9-2.0-2.1-1.71.9
Bone: cortical area1.42.14.7-0.9-2.21.41.3-1.52.20.01.5-0.4
Bone: cortical porosity0.50.61.60.21.0-0.7-0.60.8-1.3-0.6-0.80.5
Bone: cortical porosity0.20.20.5-0.00.6-0.3-0.30.4-0.7-0.4-0.50.2
Bone: cortical thickness1.01.66.01.4-0.1-0.9-1.00.80.2-2.4-0.71.9
Bone: cortical thickness2.63.05.22.01.2-1.8-1.81.6-1.1-2.3-1.61.9
Bone: cortical tissue density2.63.44.41.41.8-1.9-1.81.9-2.1-2.1-1.71.9
Condit. Reinf. active minus inactive responses0.40.50.80.80.9-0.7-0.80.8-0.4-0.6-0.70.5
Condit. Reinf. active-inactive response ratio0.10.10.30.40.4-0.2-0.40.4-0.0-0.1-0.50.1
Condit. Reinf. active responses0.40.40.70.60.7-0.6-0.70.7-0.4-0.7-0.80.6
Condit. Reinf. inactive responses0.50.61.10.50.7-0.7-0.70.8-0.9-1.0-0.90.8
Incentive salience index mean0.30.40.90.90.6-0.7-0.70.6-0.0-0.4-0.70.4
Condit. Reinf. lever presses0.30.40.90.90.5-0.7-0.70.6-0.1-0.3-0.80.4
Condit. Reinf. active minus inactive responses1.92.33.4-1.8-1.81.81.7-1.71.41.20.9-1.1
Condit. Reinf. active-inactive response ratio0.90.91.7-1.3-1.21.11.1-1.00.80.70.3-0.6
Condit. Reinf. active responses1.72.33.9-1.3-2.01.81.6-1.71.81.01.2-1.0
Condit. Reinf. inactive responses0.40.51.60.3-1.00.60.4-0.61.3-0.00.9-0.2
Condit. Reinf. lever presses0.10.10.40.60.2-0.3-0.30.20.30.3-0.5-0.1
Condit. Reinf. lever reinforcers received0.91.22.1-0.9-1.41.31.1-1.21.40.70.9-0.8
Conditioned reinforcement - actives0.40.40.60.50.8-0.7-0.60.6-0.3-0.5-0.80.4
Conditioned reinforcement - inactives0.20.20.60.80.6-0.6-0.50.5-0.30.2-0.20.0
Conditioned locomotion1.01.12.21.11.5-1.2-1.21.2-0.8-0.6-1.10.6
Patch foraging indifference point 0 sec0.10.10.80.90.2-0.5-0.40.20.10.00.00.0
Patch foraging indifference point AUC3.43.96.32.52.3-2.4-2.22.2-1.9-1.7-0.61.4
Delay disc. indifference point, 0s delay0.50.51.1-1.0-0.40.70.8-0.70.10.70.8-0.9
Delay disc. indifference point, 16s delay1.01.01.91.11.4-1.1-1.01.1-1.2-0.6-0.60.4
Delay disc. indifference point, 2s delay0.50.51.2-0.21.1-0.3-0.20.3-0.90.9-0.8-0.8
Delay disc. indifference point, 24s delay4.24.15.22.12.3-2.2-2.22.2-2.0-1.9-1.51.7
Delay disc. indifference point, 4s delay0.80.81.50.81.2-1.0-0.91.0-1.2-0.5-0.60.5
Delay disc. indifference point, 8s delay3.53.66.61.92.6-2.1-2.02.1-2.2-0.9-1.51.0
Indifference point function ln k2.83.86.8-2.6-2.32.22.2-2.21.81.40.9-1.3
Indifference point function log k2.83.86.8-2.6-2.32.22.2-2.21.81.40.9-1.3
Patch foraging total patch changes 0 sec0.10.10.50.70.1-0.3-0.20.10.40.20.3-0.1
Patch foraging total patch changes 12 sec2.53.36.22.52.1-2.0-2.01.9-1.7-1.4-0.91.3
Patch foraging total patch changes 18 sec0.81.01.91.31.4-1.2-1.01.0-1.2-0.40.60.2
Patch foraging total patch changes 24 sec0.20.30.70.90.8-0.5-0.60.5-0.10.00.6-0.2
Patch foraging total patch changes 6 sec2.94.38.42.92.2-2.8-2.32.2-1.5-1.4-0.91.4
Patch foraging time to switch 0 sec0.60.91.80.91.1-0.8-0.91.0-1.3-0.6-0.80.7
Patch foraging water rate 0 sec1.11.72.6-1.0-1.51.11.3-1.41.61.11.6-1.1
Patch foraging water rate 12 sec0.30.41.2-0.4-1.00.50.6-0.71.10.20.3-0.3
Patch foraging water rate 18 sec0.20.20.8-0.4-0.70.30.4-0.50.90.2-0.1-0.2
Patch foraging water rate 24 sec0.30.51.0-0.8-1.00.70.7-0.70.90.20.3-0.2
Patch foraging water rate 6 sec0.20.20.3-0.5-0.40.40.5-0.50.50.50.6-0.6
Seeking ratio, delayed vs. immediate footshock0.10.10.40.3-0.10.1-0.10.00.20.1-0.60.1
Distance traveled before self-admin0.10.10.40.00.6-0.5-0.30.3-0.30.2-0.6-0.2
Distance traveled after self-admin0.60.72.3-1.00.20.40.7-0.50.21.50.2-1.5
Extensor digitorum longus weight0.10.40.9-0.8-1.00.50.5-0.50.4-0.8-0.40.6
Bone: elastic displacement0.20.20.9-0.9-0.00.40.4-0.3-0.50.20.7-0.3
Bone: elastic work0.30.41.3-0.8-0.40.50.7-0.60.10.51.2-0.7
Bone: endosteal estimation3.47.510.3-2.8-2.42.82.8-2.72.43.22.5-3.0
Bone: endosteal perimeter3.57.29.0-2.8-2.42.72.8-2.72.43.02.4-2.9
Epididymis fat weight1.74.15.5-2.3-2.31.92.2-2.22.01.61.9-1.6
Delta time in closed arm before/after self-admin0.10.10.50.3-0.4-0.2-0.0-0.10.7-0.30.50.3
Delta time in open arm before/after self-admin1.31.22.4-1.1-0.80.91.1-1.10.71.51.0-1.5
Diff in mean of infusions in LGA sessions1.01.12.0-0.8-0.70.81.0-1.00.71.41.4-1.4
Delay discount exponential model param1.41.53.1-1.2-1.71.31.3-1.31.60.51.0-0.5
Extinction: sum of active levers before priming0.70.71.3-0.3-1.00.70.8-0.90.90.91.2-0.8
Active lever presses in extinction session 60.40.41.5-0.5-0.40.20.6-0.5-0.20.61.2-0.7
Bone: final force0.10.10.40.1-0.50.10.1-0.20.6-0.50.40.2
Bone: final moment0.10.20.7-0.1-0.70.30.3-0.40.9-0.20.5-0.1
Food consumed during 24 hour testing period0.60.71.41.20.9-0.8-1.00.9-0.5-0.5-0.90.6
Glucose0.20.20.5-0.2-0.30.40.4-0.50.50.60.6-0.7
Heart weight0.20.31.00.3-0.6-0.10.3-0.41.00.31.0-0.3
Delay discount hyperbolic model param1.01.02.5-0.9-1.61.11.0-1.11.40.20.8-0.2
Intermittent access intake day 1-15 change2.12.13.1-1.6-1.01.61.5-1.41.01.81.2-1.7
Intermittent access intake escalation2.22.23.1-1.8-1.01.71.5-1.41.01.71.3-1.7
Intermittent access intake escalation 21.41.42.5-1.6-0.81.51.2-1.10.61.21.1-1.1
Intermitt. access day 1 inactive lever presses0.40.41.2-0.60.20.30.4-0.3-0.21.10.4-1.1
Intermitt. access day 15 inactive lever presses0.20.20.8-0.10.30.20.2-0.20.10.90.4-0.8
Intermitt. access escalation Index2.22.02.7-1.3-1.51.61.5-1.51.11.31.4-1.3
Intermittent access day 1 total infusions0.10.10.4-0.2-0.20.00.2-0.30.30.6-0.0-0.3
Intermittent access day 15 total infusions2.32.53.4-1.6-1.41.61.6-1.61.71.81.2-1.6
Intermittent access terminal intake (last 3 days)1.01.12.0-1.1-0.71.01.0-0.91.01.40.8-1.2
Intermittent access total infusions0.70.71.1-1.0-0.70.70.9-0.81.01.10.5-0.9
Intermittent access day 1 locomotion0.40.41.0-0.5-0.40.40.6-0.60.71.00.6-0.9
Intermittent access day 15 total locomotion0.91.01.50.91.2-1.2-1.11.1-0.7-0.8-1.10.8
Intermittent access total locomotion0.50.61.20.61.0-1.1-0.80.8-0.6-0.4-0.70.5
Intermittent access standard deviation1.41.52.4-1.1-0.81.31.2-1.11.31.51.2-1.4
Left kidney weight0.20.51.30.9-0.4-0.5-0.30.11.1-0.2-1.10.4
Right kidney weight0.30.92.41.5-0.2-1.1-0.70.41.2-0.9-1.10.8
Cocaine induced anxiety0.00.10.1-0.3-0.0-0.10.2-0.10.10.40.2-0.4
Post-drug Anxiety0.10.10.30.00.3-0.4-0.30.3-0.5-0.2-0.60.3
Baseline Anxiety0.10.10.30.30.10.0-0.20.2-0.2-0.1-0.50.3
Tail length0.10.52.1-0.2-1.10.30.4-0.61.50.1-0.3-0.0
Length with tail0.10.51.30.7-0.5-0.6-0.30.11.1-0.7-1.00.8
Length without tail0.30.61.31.0-0.0-0.8-0.70.50.5-1.1-0.81.2
Times rat made contact with spout0.30.41.00.41.0-0.4-0.60.7-0.90.1-0.80.0
Lifetime Intake0.20.20.6-0.4-0.30.20.4-0.40.60.80.3-0.6
Liver weight, left0.20.40.7-0.6-0.40.60.6-0.60.80.80.4-0.7
Liver weight, right0.81.42.6-0.9-1.41.31.1-1.21.60.91.1-1.0
Locomotor activity0.00.00.10.2-0.2-0.00.1-0.10.20.20.4-0.2
Locomotor testing distance0.10.20.50.2-0.1-0.00.2-0.20.40.50.7-0.6
Locomotor testing rearing0.30.51.2-0.7-0.40.50.7-0.60.40.61.1-0.9
Locomotion in novel chamber1.62.02.5-1.6-1.51.41.6-1.51.21.31.3-1.2
Locomotion in novel chamber post-restriction0.10.10.60.70.1-0.2-0.30.20.1-0.2-0.10.1
Fecal boli incidents, locomotor time 10.10.10.20.40.4-0.1-0.30.3-0.40.00.10.2
Change in fecal boli incidents, locomotor task0.00.00.10.2-0.10.1-0.10.10.10.1-0.20.3
Time >=10cm from walls, locomotor time 10.50.51.31.10.1-0.4-0.70.50.8-0.3-1.20.8
Bouts of movement, locomotor time 12.42.63.51.51.7-1.7-1.61.6-1.6-1.7-1.91.3
Total resting periods, locomotor time 13.74.15.22.12.1-2.1-2.12.0-1.9-1.9-2.31.7
Rest time, locomotor task time 11.31.42.51.01.5-1.3-1.11.2-1.6-0.7-1.30.7
Distance moved, locomotor task time 11.41.53.5-0.9-1.51.31.1-1.21.90.81.3-0.7
Vertical activity count, locomotor time 10.60.61.3-0.4-0.70.90.6-0.71.10.50.9-0.7
Time >=10cm from walls, locomotor time 20.30.30.70.80.3-0.5-0.60.50.2-0.4-0.70.6
Bouts of movement, locomotor time 24.75.17.21.92.7-2.3-2.22.3-2.5-1.8-2.71.6
Total resting periods, locomotor time 25.45.77.82.12.8-2.5-2.42.5-2.6-1.9-2.81.7
Rest time, locomotor task time 22.22.53.11.71.7-1.8-1.71.7-1.8-1.4-1.01.4
Distance moved, locomotor task time 21.21.43.1-1.1-1.41.11.1-1.21.80.80.9-0.8
Vertical activity count, locomotor time 20.30.31.0-0.3-0.10.40.4-0.40.60.80.6-1.0
Light reinforcement 10.10.10.40.30.6-0.3-0.30.4-0.6-0.2-0.20.0
Light reinforcement 22.43.24.51.51.9-1.9-1.81.9-2.1-1.8-1.61.6
Bone: marrow area3.57.510.1-2.8-2.42.82.8-2.72.33.22.5-3.0
Bone: maximum diameter4.17.58.9-2.7-3.02.92.8-2.92.72.22.9-2.3
Bone: maximum force0.10.20.6-0.3-0.80.30.4-0.40.6-0.30.60.2
Bone: maximum moment0.20.40.9-0.5-0.90.50.6-0.60.80.00.6-0.1
Mean time between licks in bursts0.20.20.4-0.3-0.50.40.4-0.50.70.40.5-0.5
Mean num. licks in bursts2.22.73.7-1.4-1.61.81.6-1.71.91.81.1-1.7
Cd content in liver0.30.30.60.70.8-0.5-0.70.7-0.4-0.1-0.50.3
Co content in liver0.60.71.7-0.3-0.40.60.6-0.70.91.31.0-1.2
Cu content in liver6.27.513.32.83.7-3.1-2.93.0-3.1-1.7-2.11.5
Fe content in liver1.11.42.21.11.5-1.3-1.21.3-1.5-1.1-0.30.9
K content in liver0.80.71.50.71.0-0.8-0.80.9-1.0-0.4-1.20.6
Mg content in liver1.11.11.70.91.1-1.1-1.11.1-1.3-0.8-0.91.2
Mn content in liver7.68.711.72.63.1-3.1-3.03.1-3.4-2.6-2.62.9
Na content in liver2.12.23.61.31.1-1.5-1.41.4-1.5-1.9-1.31.8
Rb content in liver0.30.30.80.50.4-0.5-0.60.6-0.6-0.9-0.20.8
Se content in liver18.823.028.74.85.4-5.0-5.15.1-5.0-4.0-4.44.2
Sr content in liver0.10.10.20.30.5-0.3-0.20.2-0.20.4-0.0-0.3
Zn content in liver0.91.01.21.01.0-1.0-1.01.0-1.1-0.8-1.01.1
Bone: minimum diameter7.814.620.1-3.6-4.54.04.0-4.14.12.74.0-3.0
Time in familiar zone, hab. session 10.20.20.5-0.5-0.20.40.4-0.30.00.60.7-0.4
Time in novel zone, hab. session 10.50.50.80.70.9-0.5-0.80.8-0.7-0.6-0.70.5
Total zone transitions, hab. session 10.20.30.80.50.9-0.5-0.60.6-0.7-0.1-0.40.2
Total locomotion distance, hab. session 12.02.84.11.82.0-1.7-1.81.8-1.6-1.1-1.71.3
Locomotion velocity, hab. session 13.24.55.42.32.3-2.1-2.32.3-1.8-1.8-2.21.8
Time in familiar zone, hab. session 20.50.51.0-0.6-1.00.70.8-0.80.70.50.6-0.4
Time in novel zone, hab. session 20.70.71.40.81.2-0.8-0.90.9-0.8-0.6-0.80.4
Total zone transitions, hab. session 20.20.30.40.40.6-0.5-0.50.6-0.5-0.4-0.60.4
Total locomotion distance, hab. session 20.50.71.10.90.8-0.8-0.90.8-0.6-0.6-1.10.7
Locomotion velocity, hab. session 20.71.01.61.01.0-1.0-1.01.0-0.9-0.8-1.20.9
Novel to familiar place preference ratio0.40.41.7-0.11.0-0.4-0.40.6-1.3-0.0-0.90.1
Novelty place preference0.40.41.7-0.21.0-0.3-0.30.5-1.30.1-0.9-0.0
Time in novel zone, NPP test0.50.51.8-0.21.1-0.4-0.40.6-1.4-0.0-0.90.1
Total zone transitions, NPP test0.40.61.20.90.8-0.7-0.80.8-0.4-0.5-1.10.6
Total locomotion distance, NPP test2.83.86.02.22.1-2.0-2.12.0-1.5-1.5-2.41.6
Locomotion velocity, NPP test1.92.74.32.11.7-1.6-1.81.7-1.1-1.1-2.01.3
Intraocular pressure0.10.10.3-0.3-0.10.10.2-0.2-0.30.50.3-0.3
Delta distance traveled before/after self-admin2.32.53.3-1.8-1.31.61.7-1.61.01.81.5-1.7
Delta ambulatory time before/after self-admin3.13.44.4-2.1-1.61.92.0-1.91.32.01.6-2.0
Parametrial fat weight0.30.72.70.2-1.10.60.6-0.81.60.50.3-0.6
Pavlov. Cond. lever latency0.10.10.5-0.7-0.30.40.3-0.3-0.2-0.00.30.0
Pavlov. Cond. magazine entry latency0.50.62.01.40.8-0.7-0.80.70.20.2-1.20.0
Pavlov. Cond. change in total contacts0.10.10.50.6-0.1-0.0-0.1-0.00.70.3-0.1-0.2
Pavlov. Cond. index score0.60.72.01.40.9-0.9-0.90.8-0.1-0.3-1.10.3
Pavlov. Cond. latency score0.30.41.41.20.5-0.6-0.70.50.2-0.1-0.70.1
Pavlov. Cond. lever contacts0.30.41.31.10.5-0.7-0.70.60.1-0.5-0.50.4
Pavlov. Cond. magazine entry number0.20.30.9-0.6-0.40.10.2-0.1-0.5-0.90.60.7
Pavlov. Cond. intertrial magazine entries0.50.61.30.40.6-0.8-0.70.7-0.7-1.1-0.90.9
Pavlov. Cond. lever-magazine prob. diff.0.60.71.91.40.9-0.9-1.00.8-0.1-0.3-1.10.4
Pavlov. Cond. response bias0.30.41.01.00.7-0.5-0.60.50.30.3-1.0-0.1
Pavlov. Cond. lever latency0.50.72.0-1.4-0.91.10.9-0.80.2-0.10.8-0.2
Pavlov. Cond. magazine entry latency0.30.30.70.90.5-0.6-0.60.5-0.0-0.1-0.70.3
Pavlov. Cond. change in total contacts0.10.20.60.50.2-0.3-0.20.10.30.8-0.4-0.5
Pavlov. Cond. index score0.70.82.11.41.0-1.1-1.00.9-0.3-0.1-1.10.3
Pavlov. Cond. latency score0.70.92.11.41.0-1.1-1.00.9-0.3-0.2-1.20.4
Pavlov. Cond. lever contacts0.30.41.31.10.6-0.7-0.70.50.00.2-0.60.0
Pavlov. Cond. magazine entry number2.02.44.4-2.1-1.51.71.7-1.60.71.02.0-1.2
Pavlov. Cond. intertrial magazine entries0.50.61.6-1.3-0.61.00.9-0.80.20.60.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.70.92.11.51.0-1.2-1.00.9-0.3-0.1-1.20.4
Pavlov. Cond. response bias0.50.72.01.40.9-1.0-0.90.8-0.10.0-1.00.2
Time in closed arm before self-admin0.10.20.5-0.20.7-0.2-0.10.3-0.60.4-0.2-0.4
Time in closed arm after self-admin1.11.12.10.51.1-1.5-1.01.1-0.9-1.3-0.61.1
Time in open arm before self-admin0.00.00.1-0.3-0.00.20.2-0.1-0.20.3-0.1-0.2
Time in open arm after self-admin1.41.52.8-0.8-1.11.11.2-1.31.01.71.1-1.6
Bone: periosteal estimation2.24.55.8-2.0-2.42.22.2-2.32.31.72.1-1.8
Bone: periosteal perimeter2.94.96.3-2.3-2.52.32.3-2.42.31.72.3-1.8
Bone: post-yield work0.30.41.0-0.5-1.00.50.6-0.70.90.20.3-0.1
Progressive ratio test 1 active lever presses0.00.10.1-0.40.10.00.2-0.1-0.20.30.2-0.2
Progressive ratio test 1 breakpoint0.10.10.3-0.50.20.10.2-0.1-0.20.50.3-0.4
Progressive ratio test 1 inactive lever presses2.62.84.9-1.5-1.21.31.7-1.61.12.21.9-2.2
Progressive ratio test 2 active lever presses0.10.10.2-0.30.4-0.1-0.00.1-0.30.3-0.2-0.2
Progressive ratio test 2 breakpoint0.10.10.2-0.20.5-0.1-0.00.1-0.20.4-0.2-0.3
Progressive ratio test 2 inactive lever presses0.10.10.4-0.30.6-0.1-0.00.2-0.40.5-0.2-0.4
Incentive Sensitization - Responses0.30.30.9-0.60.10.40.4-0.30.11.0-0.0-0.8
Incentive Sensitization - Breakpoint0.20.20.7-0.40.10.40.3-0.20.10.9-0.1-0.7
Sum of active levers in priming session hrs 5-60.00.00.10.00.20.1-0.00.0-0.40.10.0-0.1
Progressive ratio0.81.02.4-0.8-1.51.21.0-1.11.10.30.8-0.4
Food seeking constrained by brief footshock0.20.30.60.7-0.0-0.5-0.50.30.1-0.7-0.40.8
Seeking ratio, punishment vs. effort1.01.32.01.21.4-1.4-1.31.2-0.9-0.6-1.00.8
Retroperitoneal fat weight0.72.24.6-1.2-2.11.41.5-1.61.80.61.7-0.8
Reaction time number correct0.60.83.2-1.8-0.70.81.1-0.90.40.50.6-0.8
Reaction time mean minus median0.50.71.3-0.4-0.81.00.7-0.81.11.10.1-0.9
Reaction time mean minus median AUC0.50.71.1-0.5-0.91.00.8-0.91.01.00.2-0.9
Reaction time num false alarms0.20.20.9-0.0-0.40.3-0.10.00.4-0.90.30.9
Reaction time num false alarms AUC0.20.20.6-0.1-0.60.40.1-0.20.8-0.60.50.5
Reaction time trials correct on left0.60.83.2-1.8-0.70.81.1-0.90.40.50.6-0.8
Reaction time trials on left0.60.93.2-1.8-0.70.81.1-0.90.50.50.5-0.8
Reaction time mean0.10.20.50.70.2-0.1-0.40.30.1-0.2-0.70.3
Reaction time mean AUC0.20.30.80.90.3-0.3-0.60.5-0.1-0.5-0.90.5
Median of all reaction times0.20.20.50.70.4-0.3-0.50.5-0.2-0.4-0.70.4
Reaction time omissions1.42.03.3-1.1-1.31.51.3-1.41.81.70.2-1.6
Reaction time false alarm rate0.20.30.90.7-0.30.1-0.40.20.5-0.90.20.9
Reaction time premature initiation rate0.10.10.50.5-0.40.4-0.1-0.00.7-0.2-0.00.4
Reaction time premature initiations0.20.30.9-0.4-0.70.80.4-0.51.00.00.20.0
Std. dev. reaction times0.40.61.7-0.2-0.80.90.6-0.71.30.9-0.1-0.8
Reaction time trials completed0.60.93.2-1.8-0.70.81.1-0.90.50.50.5-0.8
Reaction time trials AUC0.50.72.9-1.7-0.60.71.0-0.80.30.40.5-0.7
Run reversals in cocaine runway, females1.11.12.80.51.3-0.9-1.01.1-1.7-0.9-0.70.9
Run reversals in cocaine runway, males2.32.34.02.01.2-1.6-1.61.5-1.0-1.6-1.01.7
Latency to leave start box in cocaine runway4.04.36.0-2.4-1.72.12.2-2.11.72.41.8-2.3
Latency to leave start box in cocaine runway, F5.05.48.7-2.6-1.72.42.4-2.31.63.02.0-2.7
Latency to leave start box in cocaine runway, M0.50.50.9-0.9-0.60.60.7-0.70.80.70.4-0.7
Std. dev. time between licks in bursts0.30.40.60.60.7-0.6-0.60.6-0.8-0.6-0.20.5
Total sessions with >9 infusions0.20.30.70.30.8-0.8-0.50.6-0.6-0.3-0.30.1
Short access day 1 total inactive lever presses2.22.44.7-1.7-0.91.21.6-1.40.52.21.7-2.1
Short access day 10 total inactive lever presses0.10.10.40.2-0.00.20.2-0.20.00.60.4-0.6
Short access day 1 total infusions0.50.61.30.70.9-1.1-0.80.8-0.8-0.5-0.50.6
Short access day 10 total infusions0.10.10.20.40.3-0.5-0.30.30.00.0-0.40.1
Short access total infusions0.10.10.50.30.3-0.7-0.20.2-0.10.1-0.2-0.1
Short access day 1 locomotion0.20.20.4-0.50.7-0.40.00.2-0.40.50.2-0.5
Short access day 10 total locomotion0.20.20.40.40.3-0.6-0.40.4-0.5-0.5-0.20.4
Short access total locomotion0.30.30.80.20.9-0.7-0.30.4-0.80.5-0.1-0.5
One hour access (0.3 mA shock)0.50.50.9-0.9-0.60.70.8-0.70.80.80.5-0.7
Compulsive drug intake4.04.06.0-1.5-2.42.12.1-2.22.21.81.5-1.8
One hour access (shock baseline)0.20.20.5-0.70.10.10.3-0.20.40.70.5-0.7
Social response proportion1.31.43.0-1.6-0.51.31.2-1.00.21.70.5-1.5
Social responses1.72.25.1-1.2-0.81.51.4-1.41.12.31.1-2.1
Social time0.10.10.30.20.3-0.3-0.10.10.20.5-0.3-0.4
Soleus weight0.72.13.7-1.7-1.11.71.5-1.41.01.90.5-1.6
Bone: stiffness0.20.30.9-0.2-0.90.40.3-0.50.9-0.60.50.4
Tibialis anterior weight0.20.61.3-1.1-1.10.80.8-0.80.60.1-0.40.0
Time to tail flick, vehicle, before self-admin0.50.51.10.51.0-0.7-0.70.8-1.0-0.2-0.70.3
Time to tail flick, vehicle, after self-admin0.10.10.5-0.7-0.40.20.4-0.40.30.2-0.0-0.3
Time to tail flick, test, before self-admin1.01.01.9-0.9-0.61.00.9-0.90.61.31.0-1.4
Time to tail flick, test, after self-admin0.80.81.5-1.1-0.20.40.8-0.70.11.21.2-1.2
Delta time to tail flick, vehicle, before/after SA0.20.20.4-0.6-0.60.40.5-0.50.5-0.10.10.0
Delta time to tail flick, test, before/after SA0.10.10.2-0.10.1-0.4-0.10.1-0.2-0.40.00.3
Tibia length0.10.10.50.1-0.60.20.2-0.40.70.00.4-0.1
Ambulatory time before self-admin0.20.20.50.20.7-0.7-0.40.5-0.6-0.2-0.50.1
Ambulatory time after self-admin0.50.61.6-1.10.30.40.6-0.4-0.21.20.4-1.3
Bone: tissue strength0.30.30.7-0.3-0.30.40.4-0.50.40.90.6-0.6
Total heroin consumption0.10.20.80.9-0.4-0.2-0.1-0.10.50.10.4-0.2
Bone: trabecular number0.81.22.2-1.2-0.81.01.1-1.10.71.51.1-1.4
Bone: trabecular spacing0.10.20.40.7-0.1-0.3-0.40.20.4-0.5-0.00.5
Bone: trabecular thickness1.41.72.3-1.1-1.11.01.3-1.31.31.51.4-1.5
Bone: trabecular tissue density0.60.81.3-1.1-1.00.91.0-1.00.70.61.2-0.6
Water consumed over 24 hours0.40.51.30.31.1-0.5-0.60.8-1.0-0.1-0.90.2
Number of responses in last shaping day0.10.10.3-0.5-0.00.30.1-0.0-0.4-0.40.30.3