Hub : Genes

Tctn3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Tctn3 0.17 0.1 1.2e-03 0.08 0.1 0.07 0.11 5.2e-03 1.8e-03 1.1e-02 1.6e-03
2 Brain mRNA stability Tctn3 0.03 0.02 2.4e-03 0.02 0.01 0 0.01 5.9e-03 1.4e-02 3.0e-01 2.8e-02
3 pVTA gene expression Tctn3 0.07 0.04 3.5e-06 0.06 0.08 0.07 0.07 8.1e-06 1.1e-06 3.2e-06 2.5e-06
4 NAcc gene expression Tctn3 0.04 0.03 5.9e-07 0.04 0.04 0.04 0.04 8.8e-07 3.4e-07 2.6e-06 9.3e-07
5 BLA gene expression Tctn3 0.22 0.1 7.1e-11 0.21 0.18 0.19 0.2 2.8e-11 7.4e-10 3.3e-10 7.1e-11
6 PL gene expression Tctn3 0.15 0.09 3.2e-10 0.08 0.1 0.1 0.1 6.6e-09 5.5e-11 2.3e-11 5.0e-11
7 Adipose gene expression Tctn3 0.12 0.06 3.8e-12 0.08 0.07 0.07 0.08 3.2e-09 2.8e-08 6.0e-08 9.2e-09
8 Brain gene expression Tctn3 0.1 0.06 3.8e-08 0.08 0.09 0.09 0.09 6.1e-08 2.3e-08 5.8e-09 1.5e-08
9 IL gene expression Tctn3 0.14 0.09 2.3e-03 0.05 0.11 0.01 0.06 2.9e-02 1.3e-03 1.8e-01 1.9e-02
10 IC gene expression Tctn3 0.07 0.05 5.8e-03 0.03 0.04 0.01 0.03 2.5e-02 5.5e-03 9.6e-02 3.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.61.01.3-1.1-1.1-1.1-1.11.00.40.61.2-1.1-1.1
Area under the delay curve0.91.42.91.51.01.21.3-1.2-1.7-1.1-0.70.80.7
BMI with tail0.31.12.3-1.0-1.4-1.3-1.21.20.71.5-0.1-0.6-0.5
BMI without tail0.00.20.6-0.2-0.6-0.5-0.50.50.60.8-0.60.10.1
Body weight0.20.92.5-1.1-1.3-0.8-0.91.21.60.7-0.1-0.2-0.1
Weight adjusted by age0.00.10.3-0.4-0.2-0.4-0.40.30.00.2-0.50.10.2
Bone surface1.53.04.1-1.6-1.8-1.8-1.71.61.11.72.0-1.9-1.9
Bone volume1.63.34.0-1.8-2.0-1.9-1.81.81.31.72.0-1.9-1.9
Breakpoint value in progressive ratio session0.10.21.01.0-0.10.50.5-0.20.1-0.1-0.40.40.4
Number of licking bursts1.13.25.51.71.91.61.7-1.9-2.3-1.6-1.91.61.5
Context. condit. distance diff. score0.30.41.1-0.5-0.6-0.7-0.70.71.00.6-0.5-0.1-0.1
Locomotion velocity, session 14.75.37.92.62.42.32.4-2.5-2.8-2.2-1.92.01.9
Locomotion distance, session 11.62.12.91.61.61.61.7-1.7-1.4-1.0-1.11.31.3
Locomotion velocity, session 20.80.91.61.21.11.01.0-1.1-1.2-1.30.40.20.1
Locomotion distance, session 21.01.42.41.11.51.11.2-1.4-1.5-0.9-0.70.90.9
Locomotion velocity, session 30.10.10.20.10.30.30.2-0.20.50.3-0.00.10.2
Locomotion distance, session 30.30.32.3-0.5-0.2-0.1-0.20.41.50.50.4-0.2-0.2
Stereotopy head waving bouts, day 30.20.20.50.50.30.50.5-0.4-0.3-0.2-0.70.60.7
Stereotopy head waving duration, day 30.50.71.10.80.60.70.7-0.7-1.0-0.6-1.00.90.9
Locomotion velocity, session 70.70.81.3-0.9-0.6-0.8-0.80.80.90.81.1-0.9-0.9
Locomotion distance, session 70.91.11.7-1.2-0.7-1.1-1.10.90.91.01.3-1.2-1.2
Stereotopy head waving bouts, day 72.02.33.51.91.31.61.6-1.4-0.7-1.0-1.81.71.7
Stereotopy head waving duration, day 70.70.81.41.20.61.01.0-0.7-0.1-0.5-1.11.11.1
Locomotion velocity, session 80.00.00.20.30.30.10.1-0.20.1-0.1-0.40.20.2
Locomotion distance, session 80.20.21.00.40.50.20.2-0.3-0.3-0.0-1.00.50.5
Degree of sensitization distance0.20.21.80.30.30.10.1-0.3-1.4-0.5-0.30.20.1
Degree of sensitization stereotypy2.22.53.71.91.31.71.7-1.4-0.6-1.1-1.91.81.8
Conditioned locomotion1.72.04.8-1.4-1.7-1.6-1.51.61.32.20.3-0.9-0.7
Cocaine response after cond. corrected0.10.10.40.40.10.30.3-0.3-0.6-0.2-0.50.40.4
Cocaine response after cond. not corrected0.20.30.50.60.40.60.6-0.5-0.4-0.7-0.30.50.5
Cocaine response before conditioning0.81.02.30.91.21.31.2-1.0-0.1-1.5-0.30.70.7
Saline control response1.92.63.71.61.51.71.6-1.6-0.8-1.6-1.91.81.8
Bone: connectivity density2.03.24.7-1.7-1.8-1.9-1.91.60.61.42.2-2.1-2.2
Bone: cortical apparent density1.72.73.81.61.71.51.5-1.5-1.7-1.4-1.91.71.7
Bone: cortical area1.42.36.3-1.5-1.8-1.3-1.31.62.51.90.6-0.8-0.7
Bone: cortical porosity0.30.31.30.40.60.30.3-0.5-1.1-0.8-0.40.30.2
Bone: cortical porosity0.10.10.30.10.40.10.1-0.2-0.6-0.3-0.10.10.1
Bone: cortical thickness0.61.13.20.70.40.90.8-0.41.0-0.1-1.81.41.5
Bone: cortical thickness2.12.53.41.81.41.71.6-1.5-0.7-1.5-1.91.81.7
Bone: cortical tissue density1.82.83.71.61.71.51.5-1.6-1.9-1.5-1.91.71.7
Condit. Reinf. active minus inactive responses0.40.50.80.60.90.90.9-0.8-0.5-0.5-0.40.60.5
Condit. Reinf. active-inactive response ratio0.10.10.20.20.40.40.4-0.4-0.2-0.3-0.10.20.1
Condit. Reinf. active responses0.30.40.60.40.80.70.7-0.8-0.5-0.2-0.40.60.6
Condit. Reinf. inactive responses0.30.40.60.40.80.60.6-0.7-0.7-0.1-0.80.70.7
Incentive salience index mean0.30.40.70.60.80.80.8-0.7-0.1-0.4-0.20.40.4
Condit. Reinf. lever presses0.20.30.70.80.80.80.7-0.7-0.0-0.4-0.20.40.3
Condit. Reinf. active minus inactive responses1.42.13.4-1.8-1.6-1.7-1.71.61.31.10.7-1.3-1.2
Condit. Reinf. active-inactive response ratio0.50.81.5-1.2-1.1-1.2-1.21.10.50.60.2-0.7-0.7
Condit. Reinf. active responses1.42.04.5-1.5-1.4-1.5-1.51.62.11.10.8-1.1-1.0
Condit. Reinf. inactive responses0.30.54.2-0.2-0.3-0.1-0.20.62.00.40.4-0.1-0.1
Condit. Reinf. lever presses0.10.10.30.30.30.30.2-0.20.4-0.60.6-0.2-0.2
Condit. Reinf. lever reinforcers received0.81.12.9-1.1-1.0-1.0-1.01.11.70.80.6-0.8-0.7
Conditioned reinforcement - actives0.41.52.41.01.31.31.3-1.4-1.5-1.5-0.61.01.0
Conditioned reinforcement - inactives0.20.51.01.00.60.80.8-0.8-0.9-0.7-0.10.40.3
Conditioned locomotion0.40.71.30.60.91.01.0-1.1-0.8-1.10.00.40.4
Patch foraging indifference point 0 sec0.00.10.20.40.30.40.3-0.30.1-0.50.20.0-0.0
Patch foraging indifference point AUC1.74.06.82.61.92.32.3-2.3-1.9-1.5-1.41.71.6
Delay disc. indifference point, 0s delay0.30.40.6-0.5-0.6-0.8-0.70.8-0.20.6-0.0-0.7-0.7
Delay disc. indifference point, 16s delay0.60.91.51.21.11.01.0-1.0-1.1-0.8-0.80.60.6
Delay disc. indifference point, 2s delay0.30.41.90.40.10.20.3-0.2-1.4-0.40.8-0.4-0.6
Delay disc. indifference point, 24s delay2.74.35.52.22.22.32.3-2.3-2.0-1.8-1.72.01.9
Delay disc. indifference point, 4s delay0.60.71.51.10.60.91.0-0.8-1.2-0.7-0.50.70.6
Delay disc. indifference point, 8s delay2.13.55.22.21.72.02.1-2.1-2.3-2.0-1.11.41.3
Indifference point function ln k1.23.66.2-2.5-2.1-2.2-2.22.21.91.61.1-1.5-1.3
Indifference point function log k1.23.66.2-2.5-2.1-2.2-2.22.21.91.61.1-1.5-1.3
Patch foraging total patch changes 0 sec0.00.10.20.20.20.30.3-0.30.2-0.50.4-0.0-0.0
Patch foraging total patch changes 12 sec3.34.46.12.52.32.32.2-2.3-2.2-2.2-1.61.71.6
Patch foraging total patch changes 18 sec0.71.62.81.71.31.41.4-1.5-1.5-0.8-0.90.90.9
Patch foraging total patch changes 24 sec0.10.40.90.80.71.01.0-0.8-0.1-0.40.20.30.2
Patch foraging total patch changes 6 sec2.74.66.72.62.22.62.5-2.4-1.7-2.2-1.21.91.8
Patch foraging time to switch 0 sec0.31.01.61.31.10.90.9-0.9-1.2-0.9-1.00.80.8
Patch foraging water rate 0 sec0.62.13.3-1.2-1.8-1.4-1.41.51.71.81.2-1.2-1.2
Patch foraging water rate 12 sec0.10.51.4-0.7-1.0-0.6-0.70.71.20.80.3-0.5-0.4
Patch foraging water rate 18 sec0.20.51.1-0.8-0.8-0.6-0.60.61.00.80.6-0.5-0.4
Patch foraging water rate 24 sec0.30.41.0-0.7-1.0-0.7-0.70.70.70.80.1-0.3-0.3
Patch foraging water rate 6 sec0.20.30.6-0.3-0.6-0.4-0.30.40.70.70.6-0.5-0.5
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.3-0.1-0.1-0.20.10.50.10.4-0.3-0.2
Distance traveled before self-admin0.00.10.40.10.40.10.2-0.3-0.3-0.20.6-0.2-0.3
Distance traveled after self-admin0.40.73.0-0.7-0.0-0.5-0.50.3-0.40.21.7-1.1-1.2
Extensor digitorum longus weight0.10.30.9-0.9-0.5-0.6-0.60.50.40.3-0.90.30.5
Bone: elastic displacement0.10.10.3-0.3-0.3-0.5-0.40.3-0.30.5-0.0-0.2-0.2
Bone: elastic work0.30.40.8-0.4-0.7-0.7-0.70.60.10.90.4-0.6-0.6
Bone: endosteal estimation2.97.110.6-2.6-2.7-2.7-2.62.51.82.53.3-2.9-2.9
Bone: endosteal perimeter2.97.08.5-2.7-2.7-2.7-2.62.51.92.72.9-2.8-2.8
Epididymis fat weight1.04.96.7-2.2-2.5-2.6-2.62.62.42.21.1-1.7-1.6
Delta time in closed arm before/after self-admin0.10.10.6-0.1-0.2-0.0-0.10.30.80.10.2-0.1-0.1
Delta time in open arm before/after self-admin0.70.81.9-0.4-0.9-0.8-0.70.70.00.91.4-1.1-1.2
Diff in mean of infusions in LGA sessions0.81.52.2-0.6-1.5-1.2-1.11.20.71.41.3-1.3-1.4
Delay discount exponential model param1.11.43.0-1.5-1.0-1.3-1.41.31.71.10.5-0.8-0.7
Extinction: sum of active levers before priming0.30.51.0-0.1-0.8-0.5-0.60.91.01.00.7-0.5-0.5
Active lever presses in extinction session 60.50.51.7-0.0-0.9-0.9-0.80.9-0.11.3-0.0-0.6-0.6
Bone: final force0.10.20.6-0.4-0.6-0.3-0.30.50.80.70.2-0.2-0.2
Bone: final moment0.30.50.9-0.6-0.8-0.5-0.50.71.01.00.5-0.5-0.4
Food consumed during 24 hour testing period0.30.71.10.90.81.11.0-1.0-0.6-0.7-0.40.70.7
Glucose0.30.51.0-0.7-0.6-0.6-0.60.61.00.60.8-0.8-0.8
Heart weight1.62.67.0-1.4-1.7-1.3-1.31.72.61.61.3-1.4-1.3
Delay discount hyperbolic model param0.81.02.6-1.3-0.8-1.1-1.11.01.60.90.3-0.6-0.5
Intermittent access intake day 1-15 change0.21.22.0-1.4-1.0-1.1-1.11.00.70.81.2-1.2-1.1
Intermittent access intake escalation0.31.62.8-1.7-1.2-1.4-1.31.20.81.01.2-1.3-1.2
Intermittent access intake escalation 20.40.71.9-1.4-0.8-1.0-0.90.70.20.50.5-0.8-0.7
Intermitt. access day 1 inactive lever presses0.00.20.8-0.30.2-0.2-0.20.0-0.1-0.50.9-0.6-0.6
Intermitt. access day 15 inactive lever presses0.10.51.1-0.9-0.4-0.5-0.50.40.70.31.1-0.8-0.8
Intermitt. access escalation Index0.20.81.3-1.0-1.0-1.0-1.01.00.61.20.3-0.7-0.6
Intermittent access day 1 total infusions0.00.10.40.50.20.30.3-0.3-0.6-0.10.4-0.0-0.1
Intermittent access day 15 total infusions0.71.83.0-1.3-1.4-1.2-1.21.21.21.31.7-1.4-1.3
Intermittent access terminal intake (last 3 days)0.20.41.4-0.6-0.6-0.5-0.50.40.30.61.2-0.7-0.8
Intermittent access total infusions0.10.20.8-0.3-0.3-0.2-0.20.1-0.10.40.9-0.5-0.5
Intermittent access day 1 locomotion0.30.51.4-0.7-0.7-0.6-0.60.50.50.81.2-0.8-0.8
Intermittent access day 15 total locomotion0.10.50.80.90.70.90.9-0.8-0.5-0.8-0.40.70.6
Intermittent access total locomotion0.10.10.30.40.30.40.4-0.5-0.5-0.40.10.20.1
Intermittent access standard deviation0.10.72.5-0.7-0.6-0.6-0.50.40.70.51.6-1.1-1.1
Left kidney weight0.00.30.70.50.30.70.5-0.20.9-0.9-0.30.50.4
Right kidney weight0.10.81.21.00.51.10.9-0.50.7-1.0-0.91.11.1
Cocaine induced anxiety0.72.02.3-1.3-1.5-1.4-1.51.51.01.41.4-1.4-1.5
Post-drug Anxiety2.32.73.7-1.6-1.8-1.8-1.81.91.31.71.3-1.5-1.5
Baseline Anxiety0.10.20.3-0.5-0.4-0.5-0.50.60.40.40.5-0.4-0.4
Tail length0.00.21.4-0.4-0.4-0.1-0.20.41.20.10.20.00.1
Length with tail0.10.40.80.10.20.70.5-0.20.7-0.9-0.50.80.9
Length without tail0.00.20.90.00.10.50.4-0.20.2-0.9-0.50.60.6
Times rat made contact with spout0.40.41.00.40.90.60.6-0.8-0.9-1.00.10.20.1
Lifetime Intake0.20.31.2-0.2-0.4-0.3-0.30.2-0.10.51.1-0.6-0.7
Liver weight, left0.00.10.2-0.10.10.0-0.00.10.5-0.50.4-0.0-0.0
Liver weight, right0.61.01.7-0.9-1.1-0.9-0.91.01.31.11.1-0.8-0.8
Locomotor activity0.10.10.50.20.00.00.00.10.70.60.4-0.1-0.2
Locomotor testing distance0.10.31.00.5-0.10.10.10.21.00.70.8-0.4-0.4
Locomotor testing rearing0.10.51.1-0.5-0.7-0.6-0.60.71.00.90.6-0.7-0.7
Locomotion in novel chamber2.43.24.2-1.9-1.9-2.0-2.02.01.21.71.5-1.7-1.7
Locomotion in novel chamber post-restriction0.00.00.10.10.10.30.2-0.20.3-0.20.20.10.0
Fecal boli incidents, locomotor time 10.00.00.20.4-0.1-0.1-0.00.1-0.20.30.3-0.1-0.1
Change in fecal boli incidents, locomotor task0.10.10.1-0.00.20.10.1-0.20.2-0.10.30.30.4
Time >=10cm from walls, locomotor time 10.40.51.20.50.80.90.7-0.60.8-1.1-0.20.60.7
Bouts of movement, locomotor time 11.92.43.81.41.71.41.4-1.3-1.9-2.0-1.71.31.2
Total resting periods, locomotor time 13.33.85.71.92.11.91.9-1.7-2.1-2.4-1.91.71.6
Rest time, locomotor task time 11.01.63.51.21.31.11.1-1.0-1.9-1.5-1.21.00.9
Distance moved, locomotor task time 10.41.03.4-1.3-1.0-0.7-0.80.71.80.91.0-0.8-0.7
Vertical activity count, locomotor time 10.10.51.6-0.8-0.4-0.4-0.50.21.30.50.7-0.8-0.7
Time >=10cm from walls, locomotor time 20.10.40.60.60.70.80.8-0.70.3-0.6-0.40.70.7
Bouts of movement, locomotor time 21.86.19.72.52.72.32.3-2.4-3.1-2.9-2.41.91.8
Total resting periods, locomotor time 21.76.810.52.62.82.52.5-2.6-3.2-3.0-2.52.12.0
Rest time, locomotor task time 21.52.53.61.91.71.61.7-1.4-1.6-1.5-1.31.61.5
Distance moved, locomotor task time 21.11.52.8-1.7-1.4-1.1-1.11.11.71.01.0-1.0-1.0
Vertical activity count, locomotor time 20.20.51.3-0.6-0.6-0.4-0.40.40.70.21.1-1.0-1.0
Light reinforcement 10.10.61.60.70.90.60.7-1.1-1.3-0.6-0.60.50.5
Light reinforcement 21.84.05.41.91.91.91.9-2.3-2.3-1.9-2.01.91.8
Bone: marrow area2.97.110.2-2.6-2.7-2.7-2.62.51.82.53.2-2.9-2.9
Bone: maximum diameter3.87.69.2-2.9-3.0-2.8-2.82.82.83.02.3-2.6-2.4
Bone: maximum force0.20.40.8-0.6-0.9-0.6-0.60.70.70.90.0-0.2-0.2
Bone: maximum moment0.30.61.3-0.8-1.0-0.8-0.80.90.91.10.4-0.5-0.4
Mean time between licks in bursts0.10.30.6-0.6-0.6-0.5-0.50.60.50.50.8-0.6-0.6
Mean num. licks in bursts1.13.04.9-1.7-1.6-1.6-1.61.71.91.22.2-1.7-1.7
Cd content in liver1.31.52.01.11.31.31.3-1.2-1.3-1.4-0.81.11.1
Co content in liver0.70.92.7-0.7-0.8-0.4-0.50.71.20.91.6-0.9-0.9
Cu content in liver4.55.48.12.82.72.62.6-2.6-2.5-2.4-1.01.61.4
Fe content in liver2.12.63.41.81.51.71.7-1.6-1.5-1.8-1.51.51.5
K content in liver1.71.63.01.31.51.21.2-1.3-1.3-1.7-1.01.11.0
Mg content in liver1.31.41.91.31.31.11.2-1.1-1.2-1.4-0.91.21.2
Mn content in liver7.17.910.12.83.02.62.7-2.9-3.2-2.9-2.72.72.7
Na content in liver1.82.04.31.61.21.41.4-1.3-1.0-1.0-2.11.61.6
Rb content in liver0.10.10.30.20.20.30.3-0.3-0.1-0.1-0.50.40.5
Se content in liver20.524.227.75.15.35.25.2-5.3-4.5-4.9-4.24.84.7
Sr content in liver0.40.30.60.70.80.70.7-0.8-0.7-0.2-0.20.30.3
Zn content in liver2.12.53.21.81.71.71.7-1.7-1.5-1.7-1.01.41.4
Bone: minimum diameter7.314.017.6-3.9-4.2-3.8-3.83.94.24.12.9-3.3-3.1
Time in familiar zone, hab. session 10.20.20.3-0.4-0.5-0.6-0.50.40.10.50.3-0.5-0.5
Time in novel zone, hab. session 10.50.61.00.71.00.80.8-0.9-0.9-0.5-0.40.60.6
Total zone transitions, hab. session 10.20.30.50.60.70.50.6-0.7-0.60.0-0.30.30.3
Total locomotion distance, hab. session 11.92.74.01.92.01.91.9-1.9-1.5-1.2-1.21.41.4
Locomotion velocity, hab. session 13.04.25.62.32.42.32.3-2.3-1.6-1.6-1.71.91.9
Time in familiar zone, hab. session 20.30.40.9-0.4-0.9-0.7-0.70.90.70.6-0.0-0.4-0.4
Time in novel zone, hab. session 20.60.61.10.61.00.90.9-1.0-0.9-0.90.10.50.4
Total zone transitions, hab. session 20.20.20.30.40.50.50.5-0.5-0.5-0.4-0.40.40.4
Total locomotion distance, hab. session 20.50.70.80.90.90.90.9-0.8-0.7-0.8-0.80.80.7
Locomotion velocity, hab. session 20.71.01.11.11.11.11.0-1.0-0.9-1.0-1.01.00.9
Novel to familiar place preference ratio0.20.31.80.30.30.20.3-0.4-1.3-0.50.10.10.1
Novelty place preference0.20.32.00.30.40.10.2-0.4-1.4-0.50.20.1-0.0
Time in novel zone, NPP test0.30.32.20.20.40.20.3-0.5-1.5-0.60.10.10.1
Total zone transitions, NPP test0.20.40.70.60.80.80.8-0.8-0.2-0.3-0.30.50.5
Total locomotion distance, NPP test2.43.34.52.02.12.12.1-2.0-1.5-1.7-1.31.71.6
Locomotion velocity, NPP test1.62.33.51.81.71.91.8-1.7-1.0-1.3-1.01.41.3
Intraocular pressure0.00.10.20.1-0.3-0.2-0.20.5-0.10.20.3-0.1-0.2
Delta distance traveled before/after self-admin1.51.72.2-1.5-1.3-1.5-1.51.40.51.11.3-1.4-1.4
Delta ambulatory time before/after self-admin1.52.63.3-1.8-1.5-1.8-1.81.70.71.41.6-1.7-1.7
Parametrial fat weight0.10.21.80.3-0.50.1-0.00.31.3-0.2-0.10.10.0
Pavlov. Cond. lever latency0.20.20.6-0.6-0.3-0.6-0.50.4-0.80.0-0.2-0.2-0.2
Pavlov. Cond. magazine entry latency0.40.51.00.80.81.00.9-0.80.4-0.80.70.1-0.0
Pavlov. Cond. change in total contacts0.10.21.00.30.10.30.3-0.11.0-0.00.5-0.1-0.2
Pavlov. Cond. index score0.50.71.41.01.01.21.1-1.00.3-0.90.10.50.4
Pavlov. Cond. latency score0.30.40.80.80.60.90.8-0.60.6-0.60.30.30.2
Pavlov. Cond. lever contacts0.30.40.70.80.60.80.8-0.70.5-0.4-0.00.40.4
Pavlov. Cond. magazine entry number0.20.31.5-0.2-0.4-0.4-0.30.3-0.50.4-1.20.40.5
Pavlov. Cond. intertrial magazine entries0.40.50.90.50.60.70.7-0.6-0.5-0.3-0.90.91.0
Pavlov. Cond. lever-magazine prob. diff.0.50.61.31.01.01.11.1-1.00.2-0.90.10.50.4
Pavlov. Cond. response bias0.30.30.70.50.70.80.7-0.70.4-0.40.9-0.1-0.2
Pavlov. Cond. lever latency0.30.40.7-0.9-0.6-0.9-0.80.7-0.20.9-0.6-0.10.0
Pavlov. Cond. magazine entry latency0.30.41.10.70.70.80.8-0.7-0.2-1.0-0.30.40.4
Pavlov. Cond. change in total contacts0.10.21.00.2-0.00.10.1-0.00.7-0.11.0-0.5-0.6
Pavlov. Cond. index score0.40.61.50.90.81.00.9-0.80.0-1.20.20.30.2
Pavlov. Cond. latency score0.40.61.51.00.91.01.0-0.9-0.0-1.20.10.40.3
Pavlov. Cond. lever contacts0.20.30.60.80.40.70.7-0.60.4-0.70.60.0-0.0
Pavlov. Cond. magazine entry number1.31.62.6-1.4-1.4-1.6-1.51.40.51.60.7-1.0-1.0
Pavlov. Cond. intertrial magazine entries0.30.61.0-0.9-0.8-1.0-0.90.80.40.80.4-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.40.61.61.00.91.11.0-0.9-0.1-1.30.20.30.2
Pavlov. Cond. response bias0.30.40.80.80.70.90.8-0.80.2-0.90.40.10.1
Time in closed arm before self-admin0.10.10.50.10.40.20.2-0.4-0.7-0.20.4-0.2-0.2
Time in closed arm after self-admin0.40.40.7-0.10.80.70.7-0.8-0.7-0.6-0.50.60.7
Time in open arm before self-admin0.00.10.1-0.2-0.0-0.4-0.30.4-0.0-0.0-0.2-0.1-0.1
Time in open arm after self-admin0.60.71.20.2-0.8-0.8-0.80.90.40.81.0-1.0-1.1
Bone: periosteal estimation2.25.26.3-2.3-2.5-2.3-2.32.32.32.52.1-2.1-2.1
Bone: periosteal perimeter2.55.06.4-2.3-2.4-2.3-2.32.32.22.51.8-2.1-2.0
Bone: post-yield work0.20.40.9-0.8-0.8-0.6-0.60.60.70.90.1-0.4-0.3
Progressive ratio test 1 active lever presses0.30.51.40.70.70.70.7-0.8-1.2-0.4-0.40.60.7
Progressive ratio test 1 breakpoint0.30.61.30.70.70.70.8-0.9-1.1-0.5-0.40.70.7
Progressive ratio test 1 inactive lever presses0.20.41.0-0.1-0.6-0.5-0.50.60.10.71.0-0.7-0.8
Progressive ratio test 2 active lever presses0.20.31.20.50.60.50.6-0.8-1.1-0.40.10.30.2
Progressive ratio test 2 breakpoint0.30.31.20.50.60.50.6-0.8-1.1-0.40.10.30.2
Progressive ratio test 2 inactive lever presses0.10.21.10.40.50.30.4-0.6-1.1-0.40.30.1-0.0
Incentive Sensitization - Responses0.10.20.40.10.40.40.4-0.6-0.7-0.40.3-0.0-0.1
Incentive Sensitization - Breakpoint0.10.20.40.20.50.40.5-0.6-0.6-0.40.30.0-0.0
Sum of active levers in priming session hrs 5-60.00.00.20.3-0.1-0.1-0.00.2-0.40.1-0.40.00.0
Progressive ratio0.10.30.6-0.5-0.6-0.7-0.70.70.30.5-0.3-0.4-0.3
Food seeking constrained by brief footshock0.40.51.00.70.50.80.8-0.5-0.3-0.6-0.91.01.0
Seeking ratio, punishment vs. effort0.40.91.71.01.01.31.3-1.2-0.5-0.9-0.00.90.9
Retroperitoneal fat weight0.20.71.9-0.6-1.1-0.9-0.91.01.40.7-0.2-0.3-0.2
Reaction time number correct0.20.92.2-1.5-1.0-1.2-1.10.90.20.80.5-0.8-0.7
Reaction time mean minus median0.10.71.1-0.7-0.6-0.6-0.70.80.80.61.1-1.0-1.0
Reaction time mean minus median AUC0.10.81.1-0.8-0.8-0.8-0.91.00.80.80.8-1.0-1.1
Reaction time num false alarms0.10.20.7-0.5-0.20.10.10.00.6-0.3-0.70.70.8
Reaction time num false alarms AUC0.10.20.8-0.6-0.30.10.00.10.9-0.2-0.20.40.6
Reaction time trials correct on left0.20.92.2-1.5-1.0-1.2-1.10.90.20.80.5-0.8-0.7
Reaction time trials on left0.30.92.3-1.5-1.0-1.2-1.11.00.20.80.5-0.8-0.7
Reaction time mean0.00.10.20.40.30.50.4-0.3-0.0-0.1-0.20.20.2
Reaction time mean AUC0.10.20.40.60.50.60.5-0.5-0.3-0.3-0.60.40.4
Median of all reaction times0.20.30.40.60.40.60.6-0.6-0.4-0.3-0.50.50.5
Reaction time omissions0.40.61.0-0.8-0.7-0.7-0.80.90.50.10.7-0.9-1.0
Reaction time false alarm rate0.20.30.80.20.20.60.5-0.30.8-0.4-0.50.80.9
Reaction time premature initiation rate0.10.20.70.00.60.50.4-0.30.8-0.3-0.40.40.5
Reaction time premature initiations0.10.20.9-0.70.0-0.1-0.20.21.00.0-0.1-0.00.1
Std. dev. reaction times0.20.50.9-0.6-0.5-0.5-0.60.60.90.71.0-0.9-0.9
Reaction time trials completed0.30.92.3-1.5-1.0-1.2-1.11.00.20.80.5-0.8-0.7
Reaction time trials AUC0.20.71.9-1.4-0.9-1.1-1.00.90.10.70.4-0.7-0.6
Run reversals in cocaine runway, females1.82.04.11.01.51.21.3-1.5-2.0-1.3-1.51.31.3
Run reversals in cocaine runway, males1.61.72.51.61.21.61.5-1.3-0.3-1.1-1.11.51.5
Latency to leave start box in cocaine runway3.44.75.8-2.3-2.0-2.2-2.22.12.02.02.4-2.2-2.1
Latency to leave start box in cocaine runway, F5.56.99.5-2.5-2.6-2.7-2.62.52.22.53.1-2.8-2.8
Latency to leave start box in cocaine runway, M0.20.20.7-0.8-0.1-0.4-0.40.30.40.20.2-0.3-0.3
Std. dev. time between licks in bursts0.20.40.70.70.50.60.6-0.7-0.8-0.1-0.70.60.6
Total sessions with >9 infusions0.10.20.60.40.30.30.3-0.4-0.8-0.10.7-0.2-0.2
Short access day 1 total inactive lever presses0.91.92.9-0.8-1.3-1.5-1.41.3-0.11.71.6-1.6-1.7
Short access day 10 total inactive lever presses0.00.10.30.0-0.3-0.2-0.20.40.60.10.5-0.4-0.4
Short access day 1 total infusions0.30.51.31.20.60.80.8-0.8-1.0-0.3-0.10.60.5
Short access day 10 total infusions0.61.01.41.01.11.21.1-1.2-1.2-0.9-0.40.90.8
Short access total infusions0.10.10.50.50.20.30.3-0.3-0.50.00.7-0.1-0.2
Short access day 1 locomotion0.20.31.3-0.2-0.1-0.2-0.1-0.1-0.60.31.1-0.6-0.6
Short access day 10 total locomotion0.20.81.10.80.80.90.9-0.9-0.7-0.7-0.91.01.0
Short access total locomotion0.20.31.20.30.60.50.5-0.8-1.1-0.50.5-0.0-0.1
One hour access (0.3 mA shock)0.10.10.3-0.4-0.4-0.3-0.30.2-0.10.20.6-0.4-0.4
Compulsive drug intake2.13.14.2-1.5-1.8-1.9-1.92.02.01.81.4-1.6-1.5
One hour access (shock baseline)0.10.20.40.10.30.50.5-0.6-0.7-0.40.60.0-0.0
Social response proportion0.91.22.0-1.1-0.7-1.3-1.21.0-0.30.61.4-1.3-1.4
Social responses1.92.55.6-1.2-1.2-1.5-1.41.41.11.02.4-2.0-2.0
Social time0.10.21.3-0.1-0.10.10.00.00.30.01.1-0.5-0.5
Soleus weight0.82.43.2-1.7-1.5-1.7-1.71.50.91.01.8-1.8-1.8
Bone: stiffness0.20.40.9-0.7-0.7-0.5-0.50.61.01.0-0.3-0.00.1
Tibialis anterior weight0.10.51.3-1.1-0.8-0.9-0.90.80.50.7-0.1-0.3-0.2
Time to tail flick, vehicle, before self-admin0.50.61.50.90.80.60.7-0.8-1.2-1.0-0.50.50.4
Time to tail flick, vehicle, after self-admin0.00.10.2-0.5-0.2-0.3-0.30.3-0.3-0.4-0.2-0.1-0.2
Time to tail flick, test, before self-admin0.40.41.1-0.3-0.6-0.5-0.50.40.50.41.1-0.9-1.0
Time to tail flick, test, after self-admin0.10.11.00.30.30.20.3-0.4-1.00.10.10.10.1
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.5-0.3-0.2-0.20.20.20.2-0.40.10.2
Delta time to tail flick, test, before/after SA0.70.81.30.61.00.80.8-0.8-1.2-0.6-1.11.01.1
Tibia length0.00.10.7-0.20.1-0.1-0.10.10.80.30.0-0.1-0.0
Ambulatory time before self-admin0.00.10.20.10.50.20.3-0.4-0.3-0.00.5-0.0-0.0
Ambulatory time after self-admin0.50.82.4-0.9-0.3-0.8-0.70.5-0.40.61.6-1.1-1.2
Bone: tissue strength0.40.51.1-0.6-0.7-0.6-0.60.60.60.31.1-0.8-0.8
Total heroin consumption0.50.61.10.5-1.0-0.5-0.50.90.91.00.6-0.7-0.8
Bone: trabecular number0.50.91.4-0.8-1.1-1.0-0.90.80.30.61.2-1.1-1.1
Bone: trabecular spacing0.10.10.30.20.20.40.3-0.20.5-0.2-0.30.30.4
Bone: trabecular thickness1.41.92.9-1.2-1.5-1.3-1.31.31.21.31.7-1.5-1.5
Bone: trabecular tissue density0.61.12.4-1.0-0.9-1.2-1.11.10.91.60.9-0.9-0.8
Water consumed over 24 hours0.40.71.80.70.90.80.9-1.0-1.3-1.0-0.40.50.5
Number of responses in last shaping day0.10.10.5-0.20.20.10.2-0.4-0.7-0.0-0.10.10.2