Hub : Genes

Tbcd

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA isoform ratio XM_006247864.5 0.1 0.06 1.7e-04 0.07 0.07 0.05 0.04 1.5e-04 1.5e-04 1.8e-03 3.0e-03
2 NAcc isoform ratio XM_006247864.5 0.07 0.03 2.2e-10 0.08 0.08 0.08 0.08 1.3e-11 1.2e-11 3.0e-12 1.2e-11
3 Brain isoform ratio NM_001271364.2 0.12 0.05 7.6e-15 0.15 0.17 0.17 0.17 3.3e-14 1.1e-15 2.4e-15 1.8e-15
4 NAcc gene expression Tbcd 0.07 0.03 3.1e-08 0.06 0.05 0.05 0.05 2.3e-09 1.2e-08 2.1e-08 1.2e-08
5 Adipose mRNA stability Tbcd 0.15 0.07 6.6e-11 0.09 0.08 0.08 0 3.5e-10 2.5e-09 3.7e-09 2.8e-01
6 Brain intron excision ratio chr10_107366588_107367154 0.04 0.02 3.5e-05 0.04 0.05 0.04 0.04 4.8e-05 2.3e-05 2.5e-04 1.9e-04
7 Adipose gene expression Tbcd 0.45 0.1 0.0e+00 0.37 0.34 0.37 0.35 1.9e-42 3.9e-39 1.6e-42 5.5e-40
8 pVTA isoform ratio NM_001271364.2 0.1 0.05 5.9e-07 0.06 0.08 0.09 0.08 6.1e-06 9.0e-07 1.7e-07 6.1e-07
9 IC isoform ratio NM_001271364.2 0.12 0.07 4.9e-03 0.08 0.03 0.05 0.07 2.7e-04 2.2e-02 4.1e-03 5.1e-04
10 BLA intron excision ratio chr10_107367263_107368804 0.07 0.05 9.7e-03 0.04 0.03 0.02 0 2.0e-03 9.5e-03 4.0e-02 3.1e-01
11 PL isoform ratio NM_001271364.2 0.12 0.07 3.3e-11 0.12 0.11 0.11 0.11 8.1e-13 4.6e-12 5.0e-12 3.1e-12
12 PL isoform ratio XM_006247864.5 0.06 0.03 2.8e-06 0.07 0.06 0.06 0.06 2.8e-08 2.1e-07 5.7e-07 2.5e-07
13 PL gene expression Tbcd 0.04 0.03 2.5e-05 0.06 0.04 0.04 0.05 5.7e-07 4.4e-05 8.9e-05 3.9e-06
14 PL intron excision ratio chr10_107367263_107368804 0.04 0.02 1.7e-06 0.06 0.05 0.03 0.05 7.6e-07 3.3e-06 3.3e-04 7.0e-06
15 NAcc isoform ratio NM_001271364.2 0.08 0.03 4.6e-14 0.1 0.1 0.09 0.1 2.5e-15 3.3e-15 5.7e-14 1.9e-15
16 NAcc intron excision ratio chr10_107367263_107368804 0.02 0.01 9.2e-03 0.01 0.01 0.01 0.01 7.6e-03 2.6e-02 5.0e-03 1.0e-02
17 BLA isoform ratio NM_001271364.2 0.15 0.07 2.7e-07 0.12 0.12 0.1 0.12 6.6e-07 7.9e-07 3.7e-06 9.6e-07
18 PL isoform ratio XM_006247861.5 0.03 0.02 2.2e-03 0.03 0.02 0.02 0.02 3.5e-04 1.9e-03 1.6e-03 1.5e-03
19 Liver gene expression Tbcd 0.14 0.06 0.0e+00 0.12 0.14 0.14 0.13 6.5e-13 9.3e-16 1.1e-15 2.8e-14
20 pVTA isoform ratio XM_006247864.5 0.09 0.04 4.4e-08 0.07 0.1 0.1 0.08 2.9e-06 4.1e-08 1.5e-08 6.5e-07
21 NAcc isoform ratio XM_006247861.5 0.04 0.02 1.5e-05 0.03 0.04 0.03 0.03 1.2e-05 1.6e-06 1.0e-05 6.8e-06
22 Brain isoform ratio XM_006247864.5 0.09 0.04 7.2e-11 0.13 0.12 0.1 0.11 9.4e-12 1.6e-11 9.0e-10 9.2e-11
23 OFC isoform ratio NM_001271364.2 0.36 0.15 1.1e-04 0.16 0.03 0.1 0.12 1.6e-04 8.6e-02 2.1e-03 9.7e-04
24 pVTA intron excision ratio chr10_107367263_107368804 0.1 0.06 4.5e-06 0.06 0.04 0.05 0.07 1.9e-05 1.4e-04 4.6e-05 4.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.30.61.1-0.8-0.70.8-0.7-0.70.6-0.80.50.70.80.7-0.7-0.70.70.80.80.7-0.8-0.8-1.0-0.8-1.10.40.7
Area under the delay curve2.02.33.51.91.7-1.51.61.8-1.71.51.5-1.6-1.6-1.61.61.5-1.5-1.4-0.7-1.41.31.81.11.41.4-1.6-1.4
BMI with tail0.41.44.7-2.0-1.61.2-1.3-1.21.3-1.2-1.01.10.91.0-1.0-0.90.91.01.31.1-1.0-0.50.0-0.3-0.5-2.2-1.6
BMI without tail2.36.910.1-3.1-3.22.9-2.9-2.82.6-2.7-1.52.72.93.0-3.0-2.82.82.83.12.8-2.8-2.4-2.1-2.3-2.31.01.0
Body weight1.56.714.3-3.8-3.33.3-2.9-2.93.2-2.6-2.52.62.72.7-2.7-2.62.62.72.22.6-2.5-2.4-1.5-2.0-2.2-0.5-0.4
Weight adjusted by age2.33.56.0-2.4-2.32.1-2.3-2.22.0-2.2-0.92.22.01.7-1.7-2.02.01.91.01.7-1.9-2.1-1.4-1.8-1.81.10.6
Bone surface0.40.72.1-0.8-0.80.9-0.6-0.60.6-0.8-0.80.50.70.7-0.7-0.70.70.80.30.7-0.8-1.3-1.0-1.0-1.11.21.4
Bone volume0.40.71.7-0.9-0.80.9-0.6-0.60.7-0.8-0.30.60.70.7-0.7-0.70.70.90.60.7-0.9-1.2-1.1-0.9-1.31.01.3
Breakpoint value in progressive ratio session1.01.27.30.41.0-0.01.21.1-0.11.0-2.7-1.1-1.3-1.31.31.3-1.3-1.0-0.9-1.30.90.31.20.60.9-0.2-0.3
Number of licking bursts0.20.41.3-0.3-0.60.2-0.6-0.60.2-0.40.80.70.50.5-0.5-0.60.60.70.80.5-0.7-0.3-0.9-0.3-1.10.40.4
Context. condit. distance diff. score0.70.93.8-0.8-1.10.8-0.9-0.90.4-0.51.00.80.90.8-0.8-0.90.90.91.90.8-0.8-0.9-1.5-0.7-0.70.91.0
Locomotion velocity, session 11.81.94.61.21.7-1.51.51.5-0.91.20.1-1.5-1.4-1.41.41.4-1.4-1.4-2.1-1.41.41.41.71.21.0-1.2-1.5
Locomotion distance, session 11.31.75.40.91.0-1.41.01.0-1.51.11.0-1.1-1.2-1.11.11.2-1.2-1.1-0.1-1.01.21.61.41.71.1-2.3-2.3
Locomotion velocity, session 24.45.16.42.52.5-2.42.42.4-2.32.20.7-2.4-2.3-2.22.22.3-2.3-2.3-1.9-2.22.32.42.42.32.4-2.1-2.1
Locomotion distance, session 20.20.32.40.20.0-0.3-0.00.0-0.60.11.0-0.0-0.00.0-0.00.0-0.0-0.00.70.20.10.80.50.6-0.2-1.6-1.5
Locomotion velocity, session 32.93.35.12.12.1-1.81.91.9-1.81.6-0.2-1.9-1.9-1.81.81.9-1.9-1.8-1.9-1.71.82.02.31.71.6-1.6-1.7
Locomotion distance, session 35.05.47.12.52.5-2.42.42.3-2.42.20.5-2.3-2.4-2.42.42.4-2.4-2.4-1.6-2.32.42.72.62.42.3-2.2-2.5
Stereotopy head waving bouts, day 30.30.31.10.20.4-0.60.40.4-0.30.3-0.3-0.5-0.5-0.40.40.5-0.5-0.5-1.0-0.50.60.51.00.60.5-0.9-0.8
Stereotopy head waving duration, day 30.10.20.9-0.00.1-0.40.10.2-0.30.1-0.4-0.3-0.2-0.20.20.2-0.2-0.3-0.6-0.30.40.30.80.50.3-1.0-0.7
Locomotion velocity, session 70.80.91.61.21.0-1.01.01.0-1.31.10.3-1.0-1.0-1.01.01.0-1.0-1.1-0.5-1.01.00.80.70.91.2-0.3-0.4
Locomotion distance, session 72.83.55.42.22.0-2.11.91.9-2.32.01.6-1.9-1.9-1.91.91.9-1.9-1.9-0.1-1.92.02.11.41.92.1-1.3-1.3
Stereotopy head waving bouts, day 70.50.61.5-1.2-1.20.8-0.9-0.80.8-0.6-0.20.70.80.7-0.7-0.80.80.70.20.7-0.7-1.0-0.7-0.5-0.70.10.4
Stereotopy head waving duration, day 70.50.71.4-1.1-1.20.9-0.9-0.90.8-0.80.40.80.90.9-0.9-0.90.90.80.30.7-0.8-1.0-0.8-0.7-0.80.30.4
Locomotion velocity, session 80.30.42.10.40.2-0.30.30.2-0.70.11.2-0.4-0.2-0.30.30.2-0.2-0.30.9-0.20.30.80.40.50.4-1.4-1.5
Locomotion distance, session 80.71.06.8-0.8-1.20.6-1.0-1.0-0.0-0.51.50.91.00.9-0.9-1.01.00.92.61.0-0.8-0.3-1.0-0.2-0.7-0.5-0.5
Degree of sensitization distance1.01.12.5-0.8-0.90.9-0.9-0.90.8-0.80.70.91.01.0-1.0-1.01.01.01.41.0-1.0-1.1-1.4-1.1-0.71.41.6
Degree of sensitization stereotypy0.50.51.3-1.1-1.10.8-0.8-0.80.7-0.60.20.70.80.7-0.7-0.80.80.80.60.7-0.8-0.8-0.9-0.5-0.60.20.4
Conditioned locomotion4.85.66.6-2.4-2.62.5-2.5-2.52.2-2.30.92.42.52.5-2.5-2.52.52.52.52.4-2.5-2.4-2.5-2.4-2.51.81.8
Cocaine response after cond. corrected0.50.61.10.71.0-0.50.80.8-0.30.70.4-0.8-0.8-0.70.70.8-0.8-0.8-0.8-0.70.80.81.00.50.6-0.7-0.8
Cocaine response after cond. not corrected1.21.42.01.21.4-1.11.31.3-0.91.20.6-1.2-1.2-1.21.21.2-1.2-1.2-0.9-1.21.31.31.41.11.1-1.2-1.4
Cocaine response before conditioning0.60.71.61.00.5-1.00.70.7-1.31.00.3-0.7-0.7-0.80.80.6-0.6-0.8-0.0-0.80.81.00.71.10.9-0.8-1.0
Saline control response2.33.04.1-1.2-1.51.7-1.8-1.81.5-1.91.31.82.01.9-1.9-1.91.91.81.71.9-1.8-1.4-1.8-2.0-1.61.61.7
Bone: connectivity density0.20.31.1-0.2-0.40.4-0.4-0.4-0.1-0.51.10.30.50.5-0.5-0.50.50.50.90.5-0.5-0.5-0.8-0.6-0.70.60.9
Bone: cortical apparent density2.94.06.22.42.5-2.32.22.1-2.11.91.0-2.0-2.0-2.12.12.0-2.0-2.1-1.5-2.12.12.32.01.91.6-1.3-1.4
Bone: cortical area5.17.814.7-3.8-3.63.4-3.2-3.13.2-3.5-2.43.03.03.0-3.0-3.03.03.11.52.9-2.8-2.3-1.0-2.1-1.9-1.7-1.2
Bone: cortical porosity0.60.69.7-0.8-0.50.5-0.4-0.40.9-0.3-3.10.50.10.1-0.1-0.10.10.2-1.40.2-0.2-0.70.4-0.1-0.30.10.2
Bone: cortical porosity0.90.99.2-1.1-0.90.9-0.8-0.71.2-0.8-3.00.80.60.5-0.5-0.60.60.6-0.90.6-0.7-1.00.0-0.6-0.70.50.6
Bone: cortical thickness4.47.312.8-3.6-3.23.0-3.1-3.03.4-3.5-2.03.02.92.9-2.9-2.92.92.90.82.8-2.6-1.6-0.3-1.8-1.8-2.8-2.2
Bone: cortical thickness1.41.64.2-1.7-1.41.3-1.4-1.41.7-1.6-0.41.51.31.3-1.3-1.31.31.30.41.2-1.1-0.40.0-0.7-0.5-2.1-1.6
Bone: cortical tissue density3.24.37.02.52.6-2.42.32.2-2.22.11.1-2.1-2.2-2.22.22.1-2.1-2.2-1.6-2.22.22.42.02.01.6-1.2-1.3
Condit. Reinf. active minus inactive responses2.42.73.8-2.0-1.81.9-1.8-1.81.8-1.8-0.12.01.81.8-1.8-1.81.81.71.51.7-1.6-1.6-1.6-1.7-1.30.90.9
Condit. Reinf. active-inactive response ratio0.91.01.8-1.2-1.11.3-1.1-1.21.1-1.4-0.21.31.11.1-1.1-1.11.11.10.81.0-0.9-0.9-0.6-1.1-0.8-0.20.1
Condit. Reinf. active responses4.45.47.1-2.7-2.42.6-2.4-2.42.5-2.30.22.62.52.5-2.5-2.52.52.52.22.5-2.4-2.3-2.5-2.3-2.01.71.6
Condit. Reinf. inactive responses1.21.53.2-1.3-1.21.1-1.2-1.11.3-0.90.51.21.11.2-1.2-1.11.11.31.21.2-1.3-1.2-1.7-1.1-1.11.81.2
Incentive salience index mean1.82.23.1-1.7-1.51.7-1.6-1.51.6-1.40.31.81.51.6-1.6-1.51.51.51.51.5-1.5-1.5-1.6-1.5-1.21.01.0
Condit. Reinf. lever presses0.10.11.5-0.10.1-0.00.00.1-0.10.41.20.1-0.0-0.00.00.0-0.0-0.00.9-0.00.0-0.0-0.70.10.20.40.2
Condit. Reinf. active minus inactive responses1.01.32.3-1.5-1.51.4-1.4-1.41.2-1.40.21.31.21.2-1.2-1.21.21.21.01.2-1.1-0.9-0.8-1.0-0.7-0.8-0.4
Condit. Reinf. active-inactive response ratio2.73.15.6-2.4-2.12.1-2.0-2.02.2-2.0-0.52.01.81.9-1.9-1.81.81.90.81.9-1.8-1.8-1.3-1.7-1.70.20.4
Condit. Reinf. active responses0.20.30.9-0.6-0.70.7-0.6-0.60.4-0.60.20.50.40.4-0.4-0.40.40.50.80.5-0.4-0.2-0.3-0.30.0-0.9-0.5
Condit. Reinf. inactive responses1.01.32.51.41.2-0.91.11.1-1.41.00.2-1.2-1.1-1.21.21.2-1.2-1.1-0.2-1.11.21.31.01.11.6-1.3-0.9
Condit. Reinf. lever presses0.20.31.1-0.4-0.50.5-0.6-0.60.3-0.40.40.60.50.6-0.6-0.50.50.61.10.7-0.5-0.2-0.5-0.4-0.5-0.00.4
Condit. Reinf. lever reinforcers received0.20.30.9-0.7-0.80.8-0.6-0.60.4-0.50.10.50.40.5-0.5-0.40.40.51.00.5-0.4-0.3-0.4-0.3-0.1-0.8-0.4
Conditioned reinforcement - actives0.10.20.60.70.5-0.70.50.6-0.70.70.2-0.6-0.3-0.30.30.4-0.4-0.3-0.0-0.20.40.80.50.70.3-0.5-0.5
Conditioned reinforcement - inactives0.00.10.20.10.30.00.20.20.10.4-0.0-0.3-0.3-0.20.20.3-0.3-0.20.3-0.10.30.20.20.10.30.30.1
Conditioned locomotion0.10.10.30.50.3-0.20.40.4-0.60.1-0.5-0.10.30.3-0.3-0.20.20.10.10.00.00.30.40.30.20.10.2
Patch foraging indifference point 0 sec0.00.10.70.30.10.1-0.2-0.2-0.0-0.00.80.20.0-0.20.2-0.00.00.00.1-0.10.0-0.0-0.3-0.30.30.50.5
Patch foraging indifference point AUC0.20.20.6-0.4-0.20.2-0.4-0.40.4-0.30.50.40.40.6-0.6-0.40.40.50.70.7-0.5-0.3-0.7-0.3-0.50.80.4
Delay disc. indifference point, 0s delay0.10.11.0-0.0-0.20.0-0.3-0.2-0.0-0.20.50.10.0-0.00.0-0.20.20.1-0.10.20.10.20.20.10.1-0.9-1.0
Delay disc. indifference point, 16s delay1.61.73.21.71.2-1.41.31.3-1.81.51.6-1.3-1.4-1.41.41.4-1.4-1.20.3-1.31.01.60.51.51.1-1.1-1.1
Delay disc. indifference point, 2s delay0.70.81.40.80.9-0.80.91.1-0.81.00.2-0.9-1.0-0.90.90.9-0.9-0.9-0.8-0.81.20.80.80.81.2-0.6-0.8
Delay disc. indifference point, 24s delay5.46.07.92.72.8-2.52.82.8-2.52.4-0.4-2.8-2.7-2.62.62.8-2.8-2.4-2.2-2.52.12.52.42.42.1-2.0-1.8
Delay disc. indifference point, 4s delay0.50.53.11.10.9-0.50.70.8-0.70.21.8-0.6-0.5-0.50.50.4-0.4-0.4-0.3-0.20.41.00.40.30.4-1.1-1.1
Delay disc. indifference point, 8s delay1.41.62.61.51.4-1.01.21.4-1.01.11.5-1.5-1.5-1.41.41.3-1.3-1.1-1.0-1.31.01.40.91.01.1-1.6-1.4
Indifference point function ln k0.71.24.01.00.7-1.00.80.8-1.20.61.6-0.9-0.7-1.01.00.8-0.8-1.0-0.6-1.11.01.21.11.01.2-2.0-1.7
Indifference point function log k0.71.24.01.00.7-1.00.80.8-1.20.61.6-0.9-0.7-1.01.00.8-0.8-1.0-0.6-1.11.01.21.11.01.2-2.0-1.7
Patch foraging total patch changes 0 sec0.10.11.40.20.00.2-0.2-0.20.0-0.11.20.30.1-0.10.1-0.10.10.10.2-0.0-0.10.0-0.4-0.30.20.30.4
Patch foraging total patch changes 12 sec0.10.10.9-0.10.20.1-0.1-0.10.40.2-0.30.1-0.10.1-0.10.0-0.00.00.00.1-0.1-0.2-0.5-0.30.31.00.8
Patch foraging total patch changes 18 sec0.10.11.10.20.2-0.00.0-0.0-0.30.21.00.1-0.1-0.00.00.1-0.1-0.10.70.10.10.2-0.50.00.50.10.2
Patch foraging total patch changes 24 sec0.30.40.7-0.6-0.50.8-0.7-0.70.7-0.80.10.70.60.7-0.7-0.60.60.70.80.7-0.6-0.5-0.7-0.8-0.50.60.5
Patch foraging total patch changes 6 sec0.40.61.0-0.6-0.60.6-0.9-0.90.9-0.70.51.00.70.8-0.8-0.70.70.80.30.9-0.8-0.7-0.9-0.8-0.80.80.7
Patch foraging time to switch 0 sec0.30.51.00.60.7-0.80.80.8-0.81.0-0.2-0.7-0.9-0.90.90.8-0.8-0.9-0.7-0.90.80.40.50.80.80.0-0.1
Patch foraging water rate 0 sec0.51.02.7-0.6-0.81.3-0.9-0.91.1-1.00.80.81.11.0-1.0-1.01.01.11.61.0-1.0-0.5-1.1-1.2-1.10.30.4
Patch foraging water rate 12 sec0.20.31.5-0.4-0.40.4-0.4-0.40.3-0.41.20.40.40.3-0.3-0.30.30.31.10.3-0.20.4-0.2-0.1-0.2-1.2-1.2
Patch foraging water rate 18 sec0.40.72.2-0.8-1.00.8-0.8-0.80.5-0.90.70.70.80.9-0.9-0.80.80.91.50.9-0.9-0.3-0.6-0.5-1.0-0.7-0.4
Patch foraging water rate 24 sec0.91.24.4-1.1-1.31.5-1.1-1.10.9-1.2-0.71.01.21.2-1.2-1.21.21.22.11.1-1.1-0.6-0.8-1.0-0.8-0.10.1
Patch foraging water rate 6 sec0.30.54.00.30.4-0.20.30.3-0.30.2-0.2-0.4-0.2-0.30.30.3-0.3-0.40.5-0.40.61.10.90.60.6-2.0-1.8
Seeking ratio, delayed vs. immediate footshock1.41.72.7-1.2-1.21.4-1.4-1.51.3-1.60.41.51.61.3-1.3-1.61.61.51.31.2-1.4-1.1-1.2-1.4-1.40.60.6
Distance traveled before self-admin0.20.31.0-0.2-0.10.8-0.2-0.20.6-0.8-1.00.30.40.4-0.4-0.50.50.5-0.10.4-0.6-0.5-0.0-0.8-0.60.40.4
Distance traveled after self-admin0.50.65.10.0-0.10.50.00.10.1-0.2-0.9-0.10.50.5-0.5-0.50.50.61.00.5-0.7-0.7-0.9-0.6-0.82.31.3
Extensor digitorum longus weight0.31.23.3-1.6-1.40.8-1.1-1.00.8-0.71.71.01.11.1-1.1-1.11.11.11.81.2-1.1-0.9-1.4-0.5-1.1-0.30.1
Bone: elastic displacement1.41.62.8-1.3-1.31.2-1.4-1.41.4-1.7-1.11.41.51.4-1.4-1.51.51.40.31.6-1.3-1.0-0.5-1.2-0.90.20.5
Bone: elastic work5.97.613.1-3.4-3.13.2-3.1-3.13.6-3.5-2.63.03.13.0-3.0-3.03.02.90.33.0-2.8-2.7-1.4-2.7-2.10.30.7
Bone: endosteal estimation0.10.20.9-0.4-0.50.20.10.1-0.30.5-1.0-0.3-0.2-0.20.20.3-0.3-0.20.8-0.40.1-0.7-0.60.20.40.70.7
Bone: endosteal perimeter0.61.33.2-1.3-1.31.5-1.0-1.00.9-1.1-1.40.80.90.9-0.9-0.90.91.00.60.8-1.1-1.8-1.1-1.3-0.81.71.4
Epididymis fat weight0.51.94.0-1.8-1.81.6-1.5-1.61.5-1.1-0.31.11.21.5-1.5-1.21.21.52.01.5-1.4-1.3-1.5-1.0-1.20.40.2
Delta time in closed arm before/after self-admin0.50.47.70.1-0.1-0.2-0.2-0.4-0.30.52.80.2-0.2-0.30.30.2-0.2-0.30.8-0.20.50.2-1.00.20.4-0.0-0.0
Delta time in open arm before/after self-admin0.60.61.10.91.1-0.81.00.9-0.60.7-0.9-0.9-0.6-0.70.70.7-0.7-0.7-0.6-0.90.80.80.80.50.60.10.2
Diff in mean of infusions in LGA sessions0.30.30.90.40.50.00.60.6-0.20.5-0.9-0.7-0.6-0.60.60.6-0.6-0.5-0.6-0.50.5-0.30.20.00.50.90.7
Delay discount exponential model param3.03.45.2-2.3-2.11.8-2.1-2.21.9-1.8-1.32.02.01.9-1.9-1.91.91.71.11.7-1.6-2.1-1.5-1.7-1.71.81.6
Extinction: sum of active levers before priming1.11.23.30.51.0-1.01.21.2-0.60.8-1.8-1.1-1.1-1.11.11.3-1.3-1.1-1.2-1.10.71.01.41.10.7-1.2-1.2
Active lever presses in extinction session 64.24.27.31.42.1-1.32.32.5-1.01.8-2.4-2.4-2.3-2.12.12.2-2.2-2.0-2.4-1.91.91.72.71.71.9-1.9-2.2
Bone: final force5.18.215.3-3.9-3.73.5-3.3-3.23.3-3.4-1.83.23.13.1-3.1-3.03.03.11.93.0-2.9-2.4-1.4-2.2-2.0-1.5-0.6
Bone: final moment5.99.517.7-4.2-3.93.8-3.6-3.53.7-3.7-2.23.53.43.3-3.3-3.23.23.31.83.2-3.1-2.8-1.7-2.5-2.3-1.2-0.3
Food consumed during 24 hour testing period0.50.71.9-0.7-0.70.7-0.8-0.80.7-0.80.30.70.90.7-0.7-0.70.70.70.50.7-0.8-0.9-1.1-1.0-1.31.21.4
Glucose7.612.027.93.03.7-3.23.43.1-2.33.0-2.9-3.5-3.6-3.63.63.7-3.7-3.7-5.3-3.63.83.04.43.13.3-2.8-2.8
Heart weight1.21.86.5-1.9-1.61.2-1.5-1.21.7-1.4-2.61.61.31.4-1.4-1.41.41.30.21.4-1.3-1.0-0.2-0.7-1.1-0.7-0.6
Delay discount hyperbolic model param2.73.04.5-2.1-2.01.7-2.0-2.11.8-1.7-1.21.91.91.8-1.8-1.81.81.61.11.6-1.6-2.0-1.4-1.6-1.61.61.5
Intermittent access intake day 1-15 change0.20.53.21.00.80.10.80.9-0.10.5-0.9-0.6-0.5-0.50.50.6-0.6-0.5-0.2-0.70.30.10.1-0.40.21.81.2
Intermittent access intake escalation0.20.42.61.10.80.10.70.8-0.20.4-0.4-0.5-0.5-0.40.40.5-0.5-0.4-0.1-0.60.30.20.1-0.40.21.61.0
Intermittent access intake escalation 20.50.55.10.60.50.50.50.60.30.0-2.3-0.3-0.2-0.20.20.2-0.2-0.3-0.5-0.30.2-0.30.4-0.70.21.81.3
Intermitt. access day 1 inactive lever presses0.41.34.0-0.9-1.01.4-0.8-0.81.1-0.8-0.71.01.21.1-1.1-1.11.11.12.01.1-1.1-1.1-1.1-1.3-1.21.61.2
Intermitt. access day 15 inactive lever presses0.40.92.1-0.5-0.70.9-0.8-0.80.5-0.9-0.61.41.00.9-0.9-1.01.01.01.40.9-1.1-0.7-0.8-0.9-1.01.11.2
Intermitt. access escalation Index0.30.51.6-0.1-0.30.5-0.3-0.20.3-0.41.10.30.30.5-0.5-0.30.30.51.10.5-0.9-0.5-1.1-0.8-0.81.21.3
Intermittent access day 1 total infusions0.20.30.9-0.7-0.60.3-0.4-0.50.5-0.40.70.70.70.7-0.7-0.70.70.70.30.7-0.9-0.3-0.4-0.1-0.8-0.5-0.1
Intermittent access day 15 total infusions0.20.20.8-0.0-0.10.4-0.00.00.4-0.30.70.30.40.5-0.5-0.40.40.50.50.3-0.7-0.3-0.6-0.5-0.80.90.8
Intermittent access terminal intake (last 3 days)0.30.32.0-0.1-0.20.6-0.1-0.10.5-0.30.20.40.50.4-0.4-0.40.40.50.40.3-0.7-0.6-0.7-0.7-0.71.41.3
Intermittent access total infusions0.20.21.9-0.1-0.10.3-0.1-0.10.3-0.21.40.40.40.4-0.4-0.40.40.40.40.3-0.6-0.2-0.6-0.3-0.60.30.3
Intermittent access day 1 locomotion0.30.41.80.70.8-0.40.90.8-0.60.61.3-0.5-0.3-0.30.30.4-0.4-0.4-0.0-0.40.30.80.50.60.4-1.0-0.6
Intermittent access day 15 total locomotion0.10.10.9-0.10.00.50.30.20.3-0.21.00.20.50.4-0.4-0.40.40.40.10.0-0.1-0.3-0.3-0.4-0.20.60.5
Intermittent access total locomotion0.10.21.30.50.6-0.00.80.7-0.20.41.2-0.4-0.1-0.20.20.1-0.1-0.20.0-0.40.30.40.20.20.3-0.3-0.1
Intermittent access standard deviation1.22.63.41.81.5-1.31.61.7-1.11.5-1.7-1.7-1.7-1.71.71.8-1.8-1.8-1.8-1.81.61.51.81.31.6-0.9-1.0
Left kidney weight0.10.64.6-1.1-0.60.4-0.3-0.10.6-0.3-2.20.10.10.2-0.2-0.10.10.0-0.5-0.00.1-0.10.90.40.7-1.8-1.7
Right kidney weight0.10.64.7-0.9-0.40.2-0.3-0.10.4-0.2-1.40.00.00.0-0.0-0.00.0-0.1-0.4-0.10.20.31.00.60.6-2.2-2.1
Cocaine induced anxiety0.50.75.80.10.70.30.30.30.7-0.1-2.4-0.4-0.4-0.50.50.4-0.4-0.5-1.4-0.50.60.31.7-0.00.7-1.2-1.0
Post-drug Anxiety1.71.84.71.11.4-0.61.11.2-0.30.8-2.1-1.5-1.3-1.31.31.3-1.3-1.3-1.9-1.31.41.22.20.81.4-1.6-1.5
Baseline Anxiety0.81.01.81.21.0-1.11.21.2-1.21.20.5-1.3-1.1-1.01.01.1-1.1-1.0-0.6-1.00.90.90.30.90.7-0.2-0.2
Tail length2.59.912.3-3.1-3.33.5-3.2-3.13.2-3.0-1.73.03.43.4-3.4-3.33.33.22.63.1-3.1-3.4-3.2-3.3-2.93.53.0
Length with tail0.52.14.8-1.9-1.62.2-1.4-1.32.1-1.4-2.11.21.51.5-1.5-1.41.41.40.51.3-1.2-1.7-1.0-1.6-1.20.80.3
Length without tail0.20.84.7-0.50.20.30.30.40.70.0-1.7-0.4-0.4-0.30.30.4-0.4-0.3-1.7-0.30.50.21.30.30.5-2.2-2.1
Times rat made contact with spout2.22.510.9-1.0-1.01.1-1.3-1.31.5-1.3-1.51.21.31.2-1.2-1.21.21.3-0.31.1-1.4-1.9-1.5-1.8-2.03.03.3
Lifetime Intake0.10.11.50.50.4-0.30.40.3-0.20.41.2-0.2-0.2-0.20.20.2-0.2-0.20.0-0.3-0.10.4-0.10.2-0.0-0.1-0.0
Liver weight, left1.62.64.21.31.4-1.51.51.3-1.31.8-1.0-1.6-1.6-1.71.71.6-1.6-1.7-1.4-1.71.81.51.71.82.0-1.8-1.8
Liver weight, right1.32.33.8-2.0-1.91.8-1.7-1.51.5-1.3-1.71.71.51.6-1.6-1.51.51.51.91.5-1.5-1.7-1.3-1.3-0.90.61.0
Locomotor activity0.91.32.01.11.1-1.21.11.2-1.21.4-1.2-1.2-1.3-1.21.21.3-1.3-1.2-0.9-1.11.21.01.21.31.3-0.7-0.5
Locomotor testing distance1.11.92.91.31.1-1.61.31.4-1.71.60.0-1.4-1.5-1.51.51.5-1.5-1.5-0.8-1.41.41.31.21.61.6-1.3-1.0
Locomotor testing rearing0.51.12.11.51.1-1.21.21.1-1.41.3-0.6-1.1-1.1-1.21.21.0-1.0-1.1-0.2-1.01.01.00.50.91.10.30.3
Locomotion in novel chamber0.20.33.7-0.1-0.2-0.1-0.2-0.2-0.30.21.90.2-0.1-0.10.10.1-0.1-0.3-0.1-0.30.7-0.0-0.40.20.6-0.4-0.8
Locomotion in novel chamber post-restriction2.54.16.2-2.0-2.12.3-1.8-2.02.1-1.80.62.02.01.9-1.9-2.02.02.01.61.9-2.1-2.5-2.5-2.3-2.02.32.3
Fecal boli incidents, locomotor time 10.10.11.0-0.00.1-0.50.50.4-0.50.5-1.0-0.3-0.1-0.10.10.1-0.1-0.10.0-0.20.20.20.20.60.2-0.20.1
Change in fecal boli incidents, locomotor task3.03.04.71.92.2-1.62.01.9-1.21.80.7-1.8-1.9-1.91.91.9-1.9-2.0-2.1-1.82.01.41.61.32.0-0.5-0.6
Time >=10cm from walls, locomotor time 10.90.93.1-0.3-0.61.0-0.7-0.80.3-0.81.40.80.90.7-0.7-0.80.80.91.80.7-1.2-0.7-1.6-1.1-1.10.91.2
Bouts of movement, locomotor time 10.60.71.40.70.6-1.20.70.7-0.80.7-0.8-0.5-0.6-0.90.90.8-0.8-0.8-1.2-0.80.70.81.11.00.8-0.9-0.7
Total resting periods, locomotor time 10.80.91.90.90.8-1.30.90.9-1.00.8-1.0-0.7-0.7-1.11.10.9-0.9-0.9-1.4-0.90.81.01.31.20.9-0.9-0.7
Rest time, locomotor task time 10.50.67.90.40.4-0.70.50.4-0.40.4-2.8-0.4-0.3-0.40.40.4-0.4-0.5-1.1-0.40.60.21.10.60.6-0.10.2
Distance moved, locomotor task time 10.40.65.00.80.8-0.10.70.8-0.40.82.2-0.8-1.0-0.80.81.0-1.0-0.60.5-0.80.20.6-0.40.10.30.1-0.3
Vertical activity count, locomotor time 10.10.33.6-0.3-0.30.7-0.5-0.50.3-0.11.90.40.20.2-0.2-0.30.30.21.10.1-0.1-0.3-1.0-0.5-0.30.40.3
Time >=10cm from walls, locomotor time 20.71.01.7-1.1-1.10.8-1.1-1.10.9-1.31.21.11.31.1-1.1-1.21.21.20.61.2-1.1-0.7-0.6-0.8-1.0-0.5-0.1
Bouts of movement, locomotor time 20.91.52.21.01.1-1.21.31.1-1.11.41.2-1.3-1.4-1.31.31.5-1.5-1.3-0.6-1.21.01.10.91.31.2-1.1-1.4
Total resting periods, locomotor time 20.40.71.20.60.6-0.80.90.7-0.91.11.0-0.8-1.0-0.90.91.1-1.1-0.9-0.1-0.70.60.70.51.00.7-0.8-1.0
Rest time, locomotor task time 20.10.11.2-0.0-0.2-0.10.1-0.1-0.10.2-1.1-0.00.00.1-0.10.1-0.10.0-0.10.1-0.2-0.6-0.4-0.0-0.30.90.8
Distance moved, locomotor task time 20.30.33.00.40.4-0.20.10.4-0.10.11.7-0.3-0.4-0.40.40.4-0.4-0.20.1-0.4-0.00.80.10.30.1-1.2-1.2
Vertical activity count, locomotor time 20.10.21.7-0.3-0.10.1-0.30.0-0.0-0.00.40.10.1-0.00.0-0.20.20.00.7-0.20.10.40.30.40.2-1.3-1.0
Light reinforcement 11.12.74.7-1.8-1.61.4-1.8-1.71.5-1.42.11.71.61.6-1.6-1.61.61.42.01.6-1.4-1.7-2.2-1.6-1.01.51.6
Light reinforcement 21.52.33.7-1.9-1.81.6-1.7-1.61.6-1.50.31.61.51.6-1.6-1.51.51.51.71.5-1.5-1.6-1.7-1.4-1.61.11.1
Bone: marrow area0.10.21.0-0.4-0.50.20.10.2-0.40.5-1.0-0.3-0.3-0.20.20.3-0.3-0.20.8-0.40.1-0.6-0.50.20.40.60.6
Bone: maximum diameter1.12.04.2-2.1-2.01.9-1.6-1.51.5-1.8-1.81.31.51.5-1.5-1.51.51.50.81.3-1.4-1.4-0.5-1.1-0.4-0.6-0.5
Bone: maximum force5.19.017.7-4.2-4.03.7-3.4-3.33.5-3.4-2.13.33.23.3-3.3-3.13.13.22.23.2-3.0-2.7-1.6-2.3-2.1-1.2-0.5
Bone: maximum moment5.810.219.9-4.5-4.23.9-3.6-3.63.8-3.7-2.53.53.43.5-3.5-3.33.33.42.03.4-3.2-3.0-1.8-2.6-2.4-0.9-0.2
Mean time between licks in bursts1.12.84.01.82.0-1.82.02.0-1.71.81.2-1.9-1.7-1.61.61.8-1.8-1.8-0.7-1.61.71.91.41.61.3-1.5-1.4
Mean num. licks in bursts0.30.52.5-0.4-0.20.6-0.4-0.40.8-0.6-1.60.20.50.5-0.5-0.40.40.3-0.70.4-0.4-1.0-0.2-0.8-0.21.41.6
Cd content in liver0.20.30.60.50.4-0.60.50.5-0.80.70.5-0.7-0.3-0.50.50.3-0.3-0.40.8-0.50.50.50.20.70.7-0.2-0.3
Co content in liver0.10.21.70.10.1-0.00.20.2-0.10.1-1.3-0.2-0.3-0.20.20.3-0.3-0.2-0.1-0.20.1-0.2-0.1-0.1-0.10.70.9
Cu content in liver0.40.51.9-0.3-0.50.7-0.6-0.60.8-0.9-1.40.60.70.6-0.6-0.70.70.6-0.40.4-0.6-0.7-0.4-1.0-0.30.81.1
Fe content in liver0.60.81.50.90.8-0.91.01.0-1.21.20.1-1.2-1.0-0.90.91.0-1.0-0.9-0.1-0.90.90.70.71.00.8-0.3-0.3
K content in liver0.80.83.6-0.2-0.50.7-0.6-0.60.2-0.61.20.50.70.7-0.7-0.70.70.81.90.6-0.7-0.5-1.4-0.9-0.81.31.4
Mg content in liver0.50.54.10.3-0.10.1-0.2-0.3-0.3-0.11.20.20.30.3-0.3-0.30.30.42.00.2-0.4-0.0-1.1-0.4-0.81.21.3
Mn content in liver0.10.10.70.0-0.10.0-0.2-0.30.2-0.40.50.20.40.3-0.3-0.40.40.40.40.5-0.30.30.1-0.1-0.8-0.2-0.4
Na content in liver0.30.30.80.90.7-0.50.50.5-0.80.50.9-0.5-0.5-0.50.50.5-0.5-0.50.5-0.50.50.60.20.30.3-0.10.0
Rb content in liver2.52.94.7-1.5-1.81.7-1.7-1.81.3-1.9-0.91.61.91.9-1.9-1.91.91.92.21.9-1.8-1.4-1.6-1.7-1.21.21.4
Se content in liver0.40.42.3-0.1-0.00.3-0.3-0.30.3-0.40.50.20.50.4-0.4-0.50.50.60.80.5-0.6-0.4-0.8-0.7-1.01.51.5
Sr content in liver0.20.21.80.40.6-0.30.30.30.00.10.2-0.2-0.3-0.20.20.3-0.3-0.4-1.3-0.20.20.30.50.1-0.7-0.0-0.3
Zn content in liver1.31.43.0-1.2-1.31.2-1.1-1.11.1-0.9-0.91.11.11.1-1.1-1.11.11.01.40.9-1.1-1.4-1.5-1.2-0.91.71.7
Bone: minimum diameter2.64.77.7-2.8-2.72.7-2.4-2.42.4-2.6-1.42.32.32.3-2.3-2.22.22.31.22.1-2.3-2.4-1.7-2.2-1.70.70.8
Time in familiar zone, hab. session 10.10.10.9-0.00.1-0.10.00.00.20.0-1.00.1-0.1-0.10.10.1-0.1-0.1-0.5-0.20.10.20.40.1-0.0-0.1-0.3
Time in novel zone, hab. session 10.10.11.80.10.0-0.00.0-0.0-0.1-0.11.3-0.10.20.2-0.2-0.20.20.10.30.3-0.10.0-0.3-0.10.10.10.2
Total zone transitions, hab. session 10.10.21.30.20.2-0.60.10.1-0.40.30.1-0.1-0.2-0.30.30.2-0.2-0.20.1-0.10.30.80.70.70.1-1.0-1.1
Total locomotion distance, hab. session 10.40.51.1-0.9-1.00.4-1.0-1.00.5-0.60.21.10.80.8-0.8-0.80.80.70.90.8-0.6-0.3-0.4-0.1-0.7-0.5-0.5
Locomotion velocity, hab. session 10.40.51.2-0.9-1.00.4-1.1-1.00.4-0.6-0.11.10.80.8-0.8-0.80.80.80.90.8-0.6-0.4-0.4-0.1-0.7-0.4-0.4
Time in familiar zone, hab. session 20.40.41.00.50.7-0.70.80.8-0.60.91.0-0.6-0.6-0.70.70.6-0.6-0.6-0.1-0.80.60.60.20.60.7-0.0-0.3
Time in novel zone, hab. session 20.10.10.6-0.0-0.10.1-0.2-0.2-0.0-0.3-0.30.10.00.2-0.2-0.00.00.10.00.3-0.10.20.30.0-0.2-0.8-0.5
Total zone transitions, hab. session 20.40.62.7-0.7-0.90.2-0.8-0.70.1-0.51.30.70.70.7-0.7-0.70.70.71.60.9-0.7-0.1-0.6-0.0-0.6-0.6-0.6
Total locomotion distance, hab. session 21.52.05.3-1.6-1.71.0-1.6-1.60.9-1.11.71.61.51.5-1.5-1.51.51.42.31.5-1.4-0.9-1.6-0.7-1.30.10.0
Locomotion velocity, hab. session 21.92.55.7-1.8-1.91.2-1.9-1.81.1-1.41.21.91.71.8-1.8-1.71.71.72.41.8-1.6-1.1-1.6-1.0-1.40.20.1
Novel to familiar place preference ratio1.92.13.8-1.7-1.51.7-1.5-1.52.0-1.8-0.91.51.51.6-1.6-1.51.51.50.11.5-1.5-1.5-1.0-1.6-1.30.60.9
Novelty place preference1.92.03.8-1.7-1.51.8-1.5-1.42.0-1.8-0.91.41.51.6-1.6-1.51.51.4-0.01.5-1.5-1.5-0.9-1.6-1.30.60.9
Time in novel zone, NPP test1.61.73.2-1.5-1.31.6-1.4-1.31.8-1.6-0.71.31.41.5-1.5-1.41.41.30.11.4-1.4-1.4-0.9-1.5-1.20.50.7
Total zone transitions, NPP test0.20.43.00.0-0.3-0.2-0.3-0.2-0.70.11.70.20.10.1-0.1-0.10.10.21.70.2-0.20.4-0.40.4-0.4-0.7-0.6
Total locomotion distance, NPP test0.60.85.2-0.8-1.00.4-1.0-0.90.0-0.41.00.90.80.9-0.9-0.80.80.92.30.9-0.8-0.2-1.0-0.1-1.0-0.2-0.2
Locomotion velocity, NPP test0.60.94.2-0.9-1.20.6-1.1-1.00.3-0.60.71.01.01.0-1.0-1.01.01.02.11.0-1.0-0.5-1.0-0.3-1.2-0.00.0
Intraocular pressure0.91.32.0-1.1-1.41.4-1.2-1.20.8-1.0-1.21.21.11.2-1.2-1.21.21.21.41.1-1.2-1.3-1.2-1.1-0.71.31.0
Delta distance traveled before/after self-admin0.40.41.30.80.8-0.81.00.9-0.80.90.1-0.9-0.4-0.40.40.6-0.6-0.50.3-0.40.40.50.00.50.41.20.3
Delta ambulatory time before/after self-admin0.60.81.81.01.0-1.21.31.3-1.11.21.1-1.2-0.6-0.70.70.7-0.7-0.70.2-0.70.70.6-0.10.70.71.10.4
Parametrial fat weight0.61.52.3-1.4-1.31.0-1.2-1.11.2-0.80.51.11.21.3-1.3-1.31.31.31.41.2-1.2-1.3-1.5-1.0-1.11.01.4
Pavlov. Cond. lever latency0.40.61.50.70.5-0.70.70.7-1.20.90.1-0.8-0.8-0.70.70.8-0.8-0.80.7-0.70.70.80.50.90.6-0.8-0.8
Pavlov. Cond. magazine entry latency0.81.02.6-1.0-0.81.4-1.0-1.01.6-1.3-0.71.11.01.0-1.0-1.01.01.0-0.30.9-0.9-1.1-0.8-1.3-0.81.00.7
Pavlov. Cond. change in total contacts0.10.11.4-0.00.3-0.00.00.10.5-0.0-0.60.1-0.0-0.10.10.0-0.0-0.1-1.2-0.20.20.10.3-0.00.5-0.1-0.1
Pavlov. Cond. index score1.72.24.1-1.6-1.41.7-1.6-1.52.0-1.7-0.31.71.61.5-1.5-1.61.61.60.21.5-1.4-1.6-1.4-1.7-1.21.31.1
Pavlov. Cond. latency score1.31.73.4-1.4-1.11.5-1.3-1.31.8-1.5-0.41.41.41.3-1.3-1.41.41.4-0.11.3-1.2-1.4-1.2-1.5-1.11.21.1
Pavlov. Cond. lever contacts0.40.40.9-0.7-0.50.6-0.6-0.60.9-0.70.20.70.70.7-0.7-0.70.70.7-0.10.6-0.6-0.7-0.7-0.7-0.60.70.6
Pavlov. Cond. magazine entry number0.91.13.11.10.8-1.31.01.0-1.81.31.5-1.1-1.0-1.01.01.0-1.0-1.00.8-0.90.91.10.51.30.8-1.0-0.7
Pavlov. Cond. intertrial magazine entries0.60.72.0-1.0-0.90.7-0.8-0.80.6-0.51.00.80.80.9-0.9-0.80.80.81.40.8-0.9-0.8-1.2-0.6-0.90.60.6
Pavlov. Cond. lever-magazine prob. diff.1.51.93.6-1.5-1.31.6-1.5-1.41.9-1.6-0.31.61.51.4-1.4-1.51.51.50.21.3-1.3-1.4-1.3-1.6-1.11.10.9
Pavlov. Cond. response bias0.50.72.2-0.9-0.61.0-0.8-0.71.5-1.0-0.80.90.80.7-0.7-0.80.80.8-0.70.7-0.7-0.8-0.5-1.0-0.60.80.5
Pavlov. Cond. lever latency1.21.62.91.41.4-1.31.31.3-0.91.10.2-1.3-1.2-1.31.31.2-1.2-1.3-1.7-1.31.31.41.31.11.3-1.2-1.4
Pavlov. Cond. magazine entry latency1.31.62.91.31.3-1.51.31.3-1.71.70.0-1.3-1.4-1.31.31.3-1.3-1.30.1-1.31.31.31.01.61.1-0.5-0.6
Pavlov. Cond. change in total contacts0.00.10.30.20.1-0.10.20.3-0.50.4-0.1-0.3-0.3-0.30.30.3-0.3-0.30.5-0.40.30.10.10.30.1-0.00.1
Pavlov. Cond. index score0.10.10.40.10.1-0.20.20.2-0.40.5-0.4-0.2-0.3-0.20.20.2-0.2-0.10.6-0.20.20.10.10.4-0.10.20.2
Pavlov. Cond. latency score0.00.10.60.00.0-0.20.10.1-0.40.4-0.2-0.1-0.2-0.10.10.1-0.1-0.00.8-0.10.10.0-0.00.3-0.20.40.3
Pavlov. Cond. lever contacts0.91.32.4-1.2-1.21.2-1.2-1.10.8-0.9-0.11.11.11.2-1.2-1.11.11.21.61.1-1.1-1.3-1.2-1.0-1.11.21.4
Pavlov. Cond. magazine entry number1.21.42.6-1.3-1.31.4-1.3-1.31.5-1.6-0.51.31.31.3-1.3-1.21.21.2-0.11.2-1.3-1.3-1.0-1.4-0.90.40.6
Pavlov. Cond. intertrial magazine entries1.82.73.7-1.6-1.81.8-1.8-1.81.6-1.90.11.81.81.7-1.7-1.81.81.81.51.8-1.9-1.5-1.6-1.7-1.80.71.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.60.40.4-0.50.50.5-0.70.8-0.3-0.5-0.5-0.40.40.5-0.5-0.40.4-0.40.40.40.30.60.00.10.1
Pavlov. Cond. response bias0.00.00.7-0.2-0.20.1-0.1-0.1-0.10.2-0.20.0-0.00.1-0.1-0.00.00.10.80.1-0.1-0.2-0.10.0-0.20.30.3
Time in closed arm before self-admin0.20.31.80.40.7-0.30.90.9-0.2-0.1-0.2-0.5-0.1-0.00.00.1-0.1-0.0-0.9-0.2-0.20.51.30.4-0.1-1.0-0.7
Time in closed arm after self-admin1.11.22.11.31.4-1.01.21.1-0.81.11.5-1.1-1.0-1.11.11.0-1.0-1.1-1.1-1.01.11.01.00.81.2-0.8-0.5
Time in open arm before self-admin1.31.54.0-1.5-1.70.8-1.5-1.60.8-1.02.01.31.01.0-1.0-1.11.11.11.21.3-0.7-1.2-1.9-0.8-1.00.30.3
Time in open arm after self-admin0.00.00.4-0.1-0.1-0.10.20.1-0.20.1-0.6-0.3-0.1-0.10.10.1-0.1-0.10.3-0.10.30.1-0.00.20.1-0.2-0.1
Bone: periosteal estimation1.53.17.2-2.7-2.62.3-2.0-1.91.9-1.9-2.11.71.71.8-1.8-1.71.71.81.31.6-1.7-2.0-1.0-1.3-1.0-0.4-0.2
Bone: periosteal perimeter2.44.17.8-2.8-2.52.7-2.2-2.12.6-2.6-2.81.92.02.0-2.0-2.02.02.10.21.8-2.0-2.3-0.9-2.0-1.20.30.2
Bone: post-yield work0.00.10.3-0.2-0.10.20.20.2-0.10.10.3-0.2-0.2-0.00.00.2-0.2-0.20.3-0.10.10.0-0.00.20.1-0.5-0.6
Progressive ratio test 1 active lever presses0.30.42.90.70.8-0.10.90.8-0.30.61.7-0.6-0.4-0.50.50.5-0.5-0.40.2-0.40.40.4-0.00.10.30.30.4
Progressive ratio test 1 breakpoint0.20.33.00.60.7-0.00.80.7-0.20.61.7-0.5-0.4-0.40.40.4-0.4-0.30.3-0.30.30.3-0.10.00.30.40.5
Progressive ratio test 1 inactive lever presses1.11.63.8-1.0-1.01.4-0.8-0.81.2-1.00.71.21.41.3-1.3-1.31.31.32.01.3-1.5-1.1-1.4-1.3-1.41.41.4
Progressive ratio test 2 active lever presses0.10.10.4-0.1-0.10.20.10.10.10.20.60.00.0-0.00.0-0.00.00.00.5-0.10.0-0.2-0.4-0.10.00.60.5
Progressive ratio test 2 breakpoint0.10.10.50.0-0.00.20.10.10.10.20.7-0.0-0.0-0.10.10.0-0.0-0.00.5-0.20.1-0.1-0.4-0.10.10.60.5
Progressive ratio test 2 inactive lever presses0.00.10.20.10.30.10.40.50.20.30.2-0.1-0.2-0.20.20.3-0.3-0.30.0-0.40.20.10.10.00.30.1-0.1
Incentive Sensitization - Responses0.40.51.0-0.8-0.80.7-0.7-0.60.7-0.5-0.10.80.70.7-0.7-0.70.70.60.80.5-0.4-0.8-0.9-0.7-0.41.01.0
Incentive Sensitization - Breakpoint0.30.40.9-0.7-0.70.6-0.6-0.50.6-0.4-0.20.70.60.6-0.6-0.60.60.50.70.3-0.3-0.8-0.8-0.6-0.30.91.0
Sum of active levers in priming session hrs 5-60.30.21.5-0.10.50.10.30.50.50.5-1.2-0.7-0.6-0.60.60.6-0.6-0.5-0.7-0.50.3-0.00.30.10.30.30.3
Progressive ratio0.60.93.60.60.6-0.80.90.9-1.00.9-1.9-0.9-1.0-0.70.71.0-1.0-0.9-0.7-0.90.60.71.21.20.9-1.2-0.9
Food seeking constrained by brief footshock0.30.41.50.80.7-0.50.60.8-0.40.4-1.2-0.5-0.7-0.60.60.7-0.7-0.4-1.1-0.40.10.30.50.20.10.50.5
Seeking ratio, punishment vs. effort0.30.41.7-0.3-0.30.4-0.5-0.50.5-0.81.30.60.70.5-0.5-0.70.70.70.50.7-0.4-0.4-0.7-0.8-0.80.80.6
Retroperitoneal fat weight2.18.912.3-3.3-3.53.4-3.1-3.02.8-2.7-1.22.83.03.1-3.1-3.13.13.23.33.1-3.2-3.2-3.2-2.8-3.02.32.5
Reaction time number correct0.40.87.2-0.4-0.70.4-0.5-0.5-0.3-0.32.40.60.60.6-0.6-0.50.50.52.70.5-0.5-0.0-1.3-0.2-0.00.00.4
Reaction time mean minus median0.30.83.00.80.8-0.80.80.8-0.61.0-1.7-0.9-1.0-0.80.80.9-0.9-0.9-1.2-0.80.70.40.60.60.80.90.1
Reaction time mean minus median AUC0.00.11.50.30.2-0.20.20.2-0.20.3-1.2-0.3-0.4-0.20.20.3-0.3-0.2-0.4-0.20.10.00.10.20.30.50.2
Reaction time num false alarms0.10.10.6-0.20.1-0.20.20.2-0.10.3-0.8-0.3-0.3-0.40.40.2-0.2-0.2-0.4-0.30.3-0.20.10.20.20.20.3
Reaction time num false alarms AUC0.10.20.40.10.3-0.50.40.4-0.50.6-0.5-0.5-0.6-0.60.60.4-0.4-0.4-0.3-0.50.50.10.20.50.40.00.1
Reaction time trials correct on left0.40.87.2-0.4-0.70.4-0.5-0.5-0.3-0.32.40.60.60.6-0.6-0.50.50.52.70.5-0.5-0.0-1.3-0.2-0.00.00.4
Reaction time trials on left0.40.87.4-0.4-0.70.4-0.5-0.5-0.3-0.22.40.60.60.6-0.6-0.50.50.52.70.5-0.5-0.0-1.3-0.2-0.00.00.4
Reaction time mean0.30.41.8-0.8-0.70.5-0.7-0.70.6-0.4-1.30.60.40.6-0.6-0.50.50.50.40.6-0.6-0.7-0.6-0.4-0.70.90.6
Reaction time mean AUC0.30.50.8-0.8-0.90.5-0.8-0.80.5-0.5-0.60.70.60.7-0.7-0.70.70.70.70.7-0.7-0.6-0.8-0.4-0.80.80.4
Median of all reaction times0.40.61.0-1.0-1.00.7-1.0-0.90.8-0.7-0.70.90.70.8-0.8-0.80.80.80.80.8-0.8-0.8-0.7-0.6-0.90.60.5
Reaction time omissions0.10.11.00.1-0.00.00.10.1-0.10.2-0.70.1-0.20.0-0.00.1-0.10.00.40.1-0.2-0.0-0.3-0.1-0.31.00.4
Reaction time false alarm rate0.40.62.90.30.6-0.70.70.7-0.30.6-1.7-0.8-0.8-0.80.80.7-0.7-0.6-1.7-0.70.70.10.80.50.30.10.0
Reaction time premature initiation rate0.81.11.91.01.1-1.31.01.0-1.01.30.4-1.0-1.3-1.21.21.4-1.4-1.3-0.8-1.31.21.00.61.11.0-0.3-0.6
Reaction time premature initiations0.30.62.50.60.5-0.90.60.6-1.01.01.6-0.5-0.8-0.60.60.9-0.9-0.80.8-0.80.70.8-0.30.80.7-0.2-0.2
Std. dev. reaction times0.20.41.90.60.5-0.70.50.5-0.60.7-1.4-0.6-0.7-0.60.60.6-0.6-0.6-0.6-0.50.40.40.40.60.50.7-0.1
Reaction time trials completed0.40.87.4-0.4-0.70.4-0.5-0.5-0.3-0.22.40.60.60.6-0.6-0.50.50.52.70.5-0.5-0.0-1.3-0.2-0.00.00.4
Reaction time trials AUC0.50.97.6-0.5-0.70.4-0.6-0.6-0.2-0.32.40.70.70.7-0.7-0.60.60.62.80.6-0.6-0.1-1.4-0.3-0.10.10.4
Run reversals in cocaine runway, females0.10.10.20.10.3-0.40.20.3-0.50.40.1-0.3-0.3-0.10.10.3-0.3-0.30.3-0.20.00.20.10.40.40.10.2
Run reversals in cocaine runway, males0.80.91.7-1.0-0.71.1-0.6-0.61.3-0.9-0.60.71.01.0-1.0-1.01.00.9-0.21.0-0.6-1.3-0.6-1.2-0.81.21.0
Latency to leave start box in cocaine runway0.20.22.10.10.3-0.60.60.8-0.60.6-1.4-0.1-0.2-0.30.30.3-0.3-0.30.1-0.30.20.20.60.70.3-0.20.1
Latency to leave start box in cocaine runway, F0.20.21.2-0.4-0.4-0.20.10.2-0.50.1-0.50.50.50.4-0.4-0.50.50.41.10.3-0.5-0.1-0.20.4-0.40.20.2
Latency to leave start box in cocaine runway, M0.40.41.80.40.5-0.40.40.6-0.10.6-1.3-0.4-0.6-0.60.60.6-0.6-0.7-0.7-0.60.60.20.70.40.7-0.40.0
Std. dev. time between licks in bursts0.50.75.7-0.3-0.50.5-0.4-0.4-0.1-0.42.00.40.70.6-0.6-0.60.60.62.40.7-0.6-0.0-1.0-0.3-0.6-0.4-0.2
Total sessions with >9 infusions0.70.92.50.90.8-1.01.00.9-0.91.01.6-0.9-0.9-1.01.01.0-1.0-1.0-0.6-1.10.61.00.51.00.7-0.9-0.7
Short access day 1 total inactive lever presses0.20.31.6-0.00.2-0.30.40.3-0.30.71.3-0.3-0.2-0.20.20.3-0.3-0.30.5-0.30.30.50.00.70.2-0.9-1.1
Short access day 10 total inactive lever presses1.02.44.1-1.5-1.81.9-1.7-1.71.6-1.5-0.21.61.71.6-1.6-1.61.61.52.01.5-1.4-1.4-1.5-1.7-1.31.11.1
Short access day 1 total infusions1.82.43.21.61.5-1.71.61.5-1.51.60.9-1.6-1.7-1.71.71.8-1.8-1.7-1.0-1.71.21.81.31.71.2-1.6-1.5
Short access day 10 total infusions0.20.31.90.0-0.10.5-0.1-0.00.5-0.20.40.30.30.3-0.3-0.30.30.30.20.3-0.7-0.6-0.8-0.6-0.51.01.4
Short access total infusions0.50.61.01.01.0-0.80.90.8-0.60.90.7-0.8-0.9-0.80.80.9-0.9-0.8-0.4-0.80.40.90.50.70.6-0.4-0.3
Short access day 1 locomotion0.91.12.01.11.1-0.91.01.0-0.80.9-0.1-1.0-1.1-1.21.21.2-1.2-1.1-1.0-1.40.71.21.21.00.8-1.4-1.0
Short access day 10 total locomotion0.30.61.70.91.1-0.71.01.1-0.30.60.4-0.7-0.6-0.60.60.6-0.6-0.8-1.3-0.70.80.70.90.51.0-0.6-0.2
Short access total locomotion0.70.91.51.01.2-0.71.21.1-0.50.91.0-1.0-0.8-0.90.90.9-0.9-1.0-1.2-1.00.91.00.90.71.0-0.9-0.6
One hour access (0.3 mA shock)0.30.41.0-0.5-0.60.4-0.6-0.60.5-0.30.60.50.60.6-0.6-0.60.60.50.70.6-0.4-0.5-0.9-0.4-0.40.91.0
Compulsive drug intake1.31.52.6-1.2-1.61.0-1.6-1.61.0-1.10.41.31.31.4-1.4-1.31.31.31.41.5-1.0-1.2-1.3-1.1-1.10.71.0
One hour access (shock baseline)0.10.11.0-0.1-0.0-0.00.10.10.10.11.00.20.30.2-0.2-0.20.20.20.30.1-0.3-0.2-0.6-0.0-0.20.50.6
Social response proportion1.01.11.71.11.1-0.71.11.1-1.11.01.1-1.1-1.1-1.21.21.2-1.2-1.0-0.0-1.31.11.20.81.00.8-1.0-1.1
Social responses0.60.76.80.70.5-0.60.40.4-0.70.52.6-0.4-0.5-0.60.60.5-0.5-0.6-0.1-0.70.70.90.40.70.8-1.4-1.3
Social time0.20.21.5-0.1-0.1-0.20.10.1-0.20.20.7-0.0-0.1-0.30.30.1-0.1-0.20.1-0.30.30.50.40.50.6-1.2-1.2
Soleus weight1.85.28.2-2.3-2.32.3-2.3-2.32.3-2.31.12.22.32.5-2.5-2.32.32.51.72.6-2.6-2.3-2.5-2.4-2.91.82.0
Bone: stiffness0.81.36.0-1.7-1.61.2-1.2-1.21.1-0.9-1.21.10.90.9-0.9-0.80.81.01.00.8-0.8-0.40.2-0.0-0.3-2.5-1.9
Tibialis anterior weight0.20.72.2-1.0-1.00.5-0.8-0.80.6-0.61.50.90.80.8-0.8-0.80.80.80.90.8-0.9-0.8-1.2-0.5-1.10.40.5
Time to tail flick, vehicle, before self-admin0.20.23.50.60.1-0.4-0.2-0.2-0.5-0.1-1.90.1-0.30.1-0.10.1-0.10.0-0.20.1-0.30.40.40.2-0.20.20.1
Time to tail flick, vehicle, after self-admin0.91.22.90.70.8-1.30.90.9-1.21.0-0.0-0.8-0.8-1.11.10.9-0.9-0.9-0.8-1.01.21.11.31.51.2-1.7-1.6
Time to tail flick, test, before self-admin0.40.41.41.11.0-0.61.11.2-0.60.6-0.0-0.9-0.2-0.40.40.2-0.2-0.4-0.2-0.40.50.80.90.50.60.0-0.2
Time to tail flick, test, after self-admin2.72.85.12.32.1-1.62.02.0-1.61.60.3-1.8-1.7-1.71.71.7-1.7-1.7-1.5-1.61.61.91.81.41.7-1.2-1.2
Delta time to tail flick, vehicle, before/after SA0.20.23.0-0.4-0.2-0.10.20.20.10.31.7-0.10.2-0.10.1-0.20.20.10.40.00.2-0.2-0.60.20.2-0.20.0
Delta time to tail flick, test, before/after SA0.90.92.10.50.8-0.70.70.6-0.50.8-0.6-0.7-1.2-1.01.01.2-1.2-1.1-1.3-1.00.80.81.00.90.8-1.4-1.3
Tibia length9.225.339.3-6.3-6.26.0-5.7-5.75.9-6.0-3.95.45.35.3-5.3-5.35.35.41.95.4-5.3-5.1-3.1-4.8-4.70.71.3
Ambulatory time before self-admin0.71.12.0-0.7-0.81.4-1.0-0.91.2-1.4-1.11.11.01.0-1.0-1.21.21.20.51.0-1.2-0.8-0.5-1.3-1.20.50.5
Ambulatory time after self-admin0.20.32.8-0.00.10.40.30.30.2-0.2-0.9-0.20.30.4-0.4-0.30.30.40.70.3-0.6-0.4-0.4-0.5-0.61.70.6
Bone: tissue strength2.32.34.5-2.0-2.11.8-1.8-1.81.4-1.7-1.01.81.61.6-1.6-1.61.61.51.61.6-1.5-1.3-0.9-1.1-1.1-0.3-0.0
Total heroin consumption0.81.02.40.30.9-0.31.31.4-0.30.7-1.6-0.9-1.0-1.11.11.0-1.0-0.7-1.3-0.90.40.51.50.80.5-1.0-1.5
Bone: trabecular number0.10.20.7-0.3-0.10.3-0.2-0.20.4-0.40.40.20.40.4-0.4-0.40.40.40.10.3-0.4-0.4-0.5-0.5-0.50.60.8
Bone: trabecular spacing0.30.44.6-0.4-0.70.4-0.5-0.5-0.3-0.01.00.50.30.4-0.4-0.30.30.42.10.5-0.4-0.1-0.70.0-0.4-0.2-0.2
Bone: trabecular thickness0.50.61.6-0.9-0.40.9-0.5-0.51.2-0.9-1.20.50.50.4-0.4-0.50.50.6-1.10.4-0.6-1.1-0.4-1.1-0.91.11.0
Bone: trabecular tissue density1.01.52.01.31.2-1.21.41.4-1.41.3-0.5-1.3-1.3-1.31.31.3-1.3-1.1-0.6-1.31.11.31.41.30.8-1.1-1.0
Water consumed over 24 hours0.10.11.00.00.0-0.0-0.2-0.20.2-0.3-0.60.10.20.0-0.0-0.10.10.0-1.0-0.0-0.1-0.4-0.1-0.4-0.50.60.9
Number of responses in last shaping day0.80.82.70.81.1-0.90.90.8-0.60.8-0.3-1.0-0.8-0.80.80.9-0.9-0.8-0.3-0.70.51.31.21.00.5-1.6-1.4