Hub : Genes

Tbcb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb mRNA stability Tbcb 0.38 0.15 9.5e-10 0.25 0.1 0.34 0.06 1.0e-06 2.4e-03 8.9e-09 1.8e-02
2 NAcc mRNA stability Tbcb 0.31 0.11 0.0e+00 0.3 0.31 0.32 0.32 7.2e-35 1.7e-36 2.7e-37 7.4e-38
3 PL gene expression Tbcb 0.16 0.08 1.8e-15 0.13 0.15 0.15 0.15 3.2e-14 4.4e-16 2.1e-16 3.6e-16
4 BLA mRNA stability Tbcb 0.35 0.13 1.7e-16 0.29 0.29 0.31 0.31 7.2e-16 4.4e-16 3.3e-17 4.0e-17
5 Brain gene expression Tbcb 0.08 0.05 6.5e-08 0.07 0.07 0.07 0.06 6.9e-07 4.7e-07 5.1e-07 1.7e-06
6 IL mRNA stability Tbcb 0.4 0.18 4.9e-08 0.2 0.03 0.22 0.07 1.6e-05 7.4e-02 6.1e-06 8.7e-03
7 LHb gene expression Tbcb 0.54 0.37 2.3e-03 0.1 -0.01 0.09 0.01 3.0e-03 8.7e-01 4.7e-03 1.8e-01
8 Brain mRNA stability Tbcb 0.48 0.07 0.0e+00 0.59 0.54 0.6 0.6 5.1e-67 3.0e-59 2.8e-69 6.7e-69
9 pVTA mRNA stability Tbcb 0.29 0.14 1.0e-11 0.25 0.24 0.22 0.25 4.1e-11 7.3e-11 7.0e-10 3.5e-11
10 OFC mRNA stability Tbcb 0.34 0.14 8.4e-08 0.25 0.2 0.24 0.07 1.4e-06 1.9e-05 1.6e-06 7.5e-03
11 Adipose mRNA stability Tbcb 0.06 0.04 4.4e-06 0.03 0.03 0.03 0.03 2.5e-04 2.9e-04 5.0e-04 6.1e-04
12 NAcc gene expression Tbcb 0.12 0.06 0.0e+00 0.15 0.14 0.14 0.15 2.2e-17 1.4e-15 1.9e-16 4.6e-17
13 Liver mRNA stability Tbcb 0.05 0.04 5.5e-07 0.04 0.04 0.04 0.04 1.6e-05 1.8e-05 3.1e-05 3.2e-05
14 pVTA gene expression Tbcb 0.11 0.09 2.6e-03 0.03 0.03 0.04 0.04 1.9e-02 2.2e-02 7.4e-03 1.2e-02
15 BLA gene expression Tbcb 0.21 0.1 1.1e-09 0.19 0.18 0.18 0.2 2.4e-10 5.7e-10 6.8e-10 9.6e-11
16 PL mRNA stability Tbcb 0.2 0.1 0.0e+00 0.24 0.25 0.25 0.25 5.0e-26 9.1e-27 5.4e-27 6.3e-27

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Bone: apparent density0.50.91.60.8-1.0-1.00.80.70.5-1.10.9-1.01.21.2-1.31.3-0.30.01.2
Area under the delay curve0.50.51.20.7-0.6-0.80.80.90.9-0.70.6-0.70.20.1-0.30.3-1.11.00.7
BMI with tail0.20.51.0-0.80.80.6-0.7-0.9-1.00.8-0.90.9-0.9-0.60.6-0.60.5-0.5-0.4
BMI without tail0.10.10.80.5-0.4-0.30.30.20.9-0.30.4-0.30.00.1-0.30.40.1-0.10.1
Body weight2.510.614.53.4-3.4-3.53.23.13.3-3.33.3-3.23.63.8-3.53.5-2.52.32.6
Weight adjusted by age0.20.21.30.1-0.3-0.40.3-0.1-0.3-0.60.2-0.40.60.5-0.40.4-0.30.0-1.1
Bone surface1.62.94.31.5-1.7-1.81.71.71.1-1.71.6-1.71.91.8-1.81.8-1.61.52.1
Bone volume1.52.63.81.4-1.6-1.81.61.51.0-1.61.5-1.61.91.9-1.81.8-1.41.21.7
Breakpoint value in progressive ratio session1.51.63.61.4-1.3-1.21.31.81.9-1.21.2-1.20.90.7-0.90.8-1.41.51.1
Number of licking bursts2.73.15.5-2.12.11.7-1.7-1.9-2.41.5-2.11.9-1.7-1.71.7-1.70.6-0.6-2.0
Context. condit. distance diff. score0.10.10.7-0.20.20.00.10.1-0.40.0-0.20.20.10.10.2-0.2-0.70.8-0.2
Locomotion velocity, session 10.70.81.4-1.01.00.9-1.1-1.0-0.70.8-0.90.9-0.5-0.50.7-0.71.2-1.2-0.9
Locomotion distance, session 10.50.61.60.6-0.5-0.80.80.80.5-0.80.5-0.61.01.0-0.70.7-1.21.30.5
Locomotion velocity, session 20.60.81.3-0.70.71.1-0.9-0.7-0.20.9-0.70.8-1.1-1.11.1-1.11.0-0.8-0.0
Locomotion distance, session 21.11.52.6-1.41.41.2-1.1-1.2-1.61.5-1.51.4-1.2-1.21.4-1.40.4-0.2-0.7
Locomotion velocity, session 30.20.30.4-0.50.50.6-0.5-0.6-0.60.5-0.50.5-0.4-0.40.7-0.70.4-0.40.1
Locomotion distance, session 33.13.46.51.9-1.9-1.82.22.11.6-1.61.7-1.71.61.6-1.21.2-2.42.61.9
Stereotopy head waving bouts, day 31.01.24.3-0.90.71.0-1.2-1.1-0.60.7-0.70.7-1.1-1.10.6-0.62.0-2.1-0.5
Stereotopy head waving duration, day 31.82.25.9-1.41.21.4-1.7-1.6-1.01.1-1.21.2-1.6-1.60.9-0.92.3-2.4-1.1
Locomotion velocity, session 70.40.41.50.4-0.5-0.60.80.70.1-0.50.4-0.50.70.7-0.40.4-1.11.20.7
Locomotion distance, session 70.10.20.50.3-0.4-0.30.50.40.1-0.20.3-0.30.70.7-0.10.1-0.50.60.6
Stereotopy head waving bouts, day 70.80.91.5-1.11.10.8-0.9-0.9-1.01.0-1.11.1-1.1-1.10.7-0.70.2-0.3-1.2
Stereotopy head waving duration, day 72.12.63.1-1.71.81.6-1.7-1.7-1.51.6-1.71.7-1.8-1.81.4-1.41.2-1.2-1.6
Locomotion velocity, session 83.44.06.4-2.32.22.1-1.9-2.0-2.51.9-2.32.2-2.0-2.02.3-2.31.0-0.8-1.4
Locomotion distance, session 80.60.92.1-1.01.00.8-0.5-0.7-1.50.9-1.11.1-0.7-0.71.2-1.2-0.50.7-0.4
Degree of sensitization distance0.60.61.4-0.90.80.7-0.9-1.0-0.80.7-0.70.7-0.4-0.40.5-0.51.1-1.2-0.8
Degree of sensitization stereotypy1.01.11.7-1.21.20.9-0.9-1.0-1.31.2-1.21.2-1.1-1.10.9-0.9-0.00.0-1.2
Conditioned locomotion0.60.71.3-0.81.00.8-0.8-0.7-0.51.1-0.90.9-1.1-1.10.8-0.80.4-0.4-1.2
Cocaine response after cond. corrected0.30.32.0-0.00.10.6-0.5-0.40.50.40.00.2-0.4-0.50.4-0.41.2-1.40.2
Cocaine response after cond. not corrected0.40.42.60.1-0.10.4-0.4-0.30.70.40.20.0-0.3-0.30.3-0.31.5-1.60.7
Cocaine response before conditioning1.31.62.91.3-1.4-1.41.31.20.9-1.21.3-1.31.31.3-1.41.4-0.80.91.7
Saline control response0.00.10.30.10.10.3-0.1-0.00.50.40.00.1-0.0-0.00.2-0.20.4-0.40.2
Bone: connectivity density0.30.41.60.5-0.7-0.60.60.50.1-0.70.6-0.70.60.6-0.70.7-0.20.11.3
Bone: cortical apparent density1.92.53.5-1.71.71.6-1.5-1.6-1.91.7-1.81.8-1.3-1.31.7-1.70.9-0.8-1.7
Bone: cortical area1.21.92.51.5-1.6-1.31.41.41.5-1.41.5-1.41.51.5-1.11.1-0.90.91.6
Bone: cortical porosity1.21.33.9-1.31.00.9-0.8-1.0-2.01.1-1.31.1-1.6-1.61.1-1.10.4-0.2-0.6
Bone: cortical porosity1.61.84.7-1.51.31.1-1.0-1.2-2.21.3-1.51.3-1.7-1.71.4-1.40.4-0.2-0.8
Bone: cortical thickness0.20.40.80.7-0.8-0.50.50.50.9-0.80.7-0.70.70.7-0.40.4-0.0-0.00.8
Bone: cortical thickness0.81.01.5-1.00.91.0-1.1-1.1-0.91.0-1.00.9-0.9-0.80.9-0.91.2-1.2-1.0
Bone: cortical tissue density2.22.94.1-1.91.81.7-1.7-1.7-2.01.8-1.91.9-1.5-1.41.8-1.81.0-0.9-1.8
Condit. Reinf. active minus inactive responses0.20.20.4-0.40.50.4-0.5-0.4-0.30.5-0.40.4-0.6-0.70.4-0.40.4-0.4-0.4
Condit. Reinf. active-inactive response ratio0.30.31.5-0.30.30.5-0.6-0.50.10.3-0.20.3-0.8-0.80.3-0.31.1-1.2-0.2
Condit. Reinf. active responses2.02.53.3-1.71.81.6-1.6-1.5-1.61.8-1.71.7-1.8-1.81.6-1.61.0-0.9-1.3
Condit. Reinf. inactive responses2.22.63.9-1.82.01.6-1.4-1.4-1.91.9-1.91.9-1.6-1.51.8-1.80.4-0.1-1.4
Incentive salience index mean0.20.20.6-0.30.40.4-0.4-0.3-0.20.5-0.40.4-0.7-0.80.5-0.50.3-0.2-0.2
Condit. Reinf. lever presses0.10.10.30.2-0.2-0.10.20.30.3-0.00.1-0.1-0.3-0.40.1-0.1-0.30.50.5
Condit. Reinf. active minus inactive responses1.61.94.91.7-1.6-1.21.41.52.2-1.21.6-1.41.01.0-0.90.9-0.90.91.9
Condit. Reinf. active-inactive response ratio0.10.10.30.00.10.3-0.2-0.20.50.2-0.10.2-0.1-0.10.5-0.50.2-0.20.2
Condit. Reinf. active responses3.75.17.52.6-2.5-2.22.42.52.7-2.12.4-2.31.91.9-1.91.9-1.91.92.7
Condit. Reinf. inactive responses4.65.77.32.5-2.6-2.52.72.72.0-2.32.4-2.41.91.9-2.22.2-2.42.62.6
Condit. Reinf. lever presses7.29.813.43.4-3.4-3.23.13.33.7-3.43.3-3.32.92.9-3.13.1-2.32.13.1
Condit. Reinf. lever reinforcers received3.95.47.02.6-2.5-2.32.52.62.6-2.22.4-2.32.12.1-2.02.0-2.22.22.6
Conditioned reinforcement - actives0.20.20.5-0.40.40.3-0.6-0.4-0.20.4-0.50.5-0.3-0.30.3-0.30.2-0.4-0.7
Conditioned reinforcement - inactives0.91.03.60.9-0.8-0.91.11.10.6-0.80.6-0.80.40.4-0.60.6-1.91.91.0
Conditioned locomotion2.22.64.8-1.91.81.6-1.6-1.4-2.21.7-1.81.7-1.6-1.61.7-1.70.7-0.7-1.0
Patch foraging indifference point 0 sec0.10.20.60.4-0.5-0.40.60.50.1-0.30.4-0.50.1-0.0-0.00.2-0.30.40.8
Patch foraging indifference point AUC0.40.50.8-0.50.50.8-0.7-0.8-0.30.6-0.60.5-0.7-0.70.8-0.80.9-0.80.7
Delay disc. indifference point, 0s delay0.40.53.20.20.2-0.50.30.60.70.1-0.10.10.30.3-0.40.4-1.71.8-0.2
Delay disc. indifference point, 16s delay1.11.12.91.3-1.0-1.01.21.41.7-1.11.1-1.10.20.2-0.40.4-1.31.21.0
Delay disc. indifference point, 2s delay1.11.33.31.0-0.8-1.21.21.21.1-0.90.8-0.81.21.1-0.90.9-1.81.70.7
Delay disc. indifference point, 24s delay2.62.53.81.8-1.7-1.72.01.81.6-1.81.7-1.71.21.1-1.11.1-1.71.80.9
Delay disc. indifference point, 4s delay0.10.10.2-0.10.2-0.0-0.10.10.1-0.0-0.10.1-0.4-0.50.3-0.4-0.40.20.3
Delay disc. indifference point, 8s delay0.30.30.50.4-0.5-0.70.70.5-0.1-0.70.5-0.70.30.3-0.40.4-0.60.60.6
Indifference point function ln k0.30.40.70.6-0.6-0.60.60.80.5-0.60.7-0.60.70.7-0.60.6-0.60.6-0.6
Indifference point function log k0.30.40.70.6-0.6-0.60.60.80.5-0.60.7-0.60.70.7-0.60.6-0.60.6-0.6
Patch foraging total patch changes 0 sec0.20.31.00.6-0.7-0.50.80.70.3-0.40.6-0.60.30.2-0.20.3-0.50.61.0
Patch foraging total patch changes 12 sec0.10.20.70.3-0.20.1-0.00.10.80.00.2-0.2-0.5-0.60.3-0.20.5-0.50.8
Patch foraging total patch changes 18 sec0.00.10.3-0.1-0.0-0.10.2-0.1-0.60.1-0.20.00.10.10.1-0.0-0.40.40.3
Patch foraging total patch changes 24 sec1.11.42.91.0-0.9-1.31.41.10.8-1.10.9-1.11.21.1-1.01.1-1.61.71.2
Patch foraging total patch changes 6 sec0.10.21.70.4-0.5-0.10.40.10.20.00.2-0.4-0.1-0.20.3-0.20.2-0.11.3
Patch foraging time to switch 0 sec0.61.01.7-0.70.81.1-1.1-0.9-0.21.0-0.70.9-1.2-1.20.9-0.91.3-1.3-0.8
Patch foraging water rate 0 sec0.60.92.0-1.10.90.9-0.8-1.0-1.40.9-1.10.9-0.9-1.01.1-1.00.6-0.4-0.5
Patch foraging water rate 12 sec0.81.22.30.8-1.0-1.31.10.80.4-1.30.8-1.01.31.3-1.21.2-1.51.30.3
Patch foraging water rate 18 sec0.10.20.7-0.50.40.2-0.3-0.5-0.80.2-0.50.3-0.5-0.50.3-0.20.2-0.2-0.5
Patch foraging water rate 24 sec0.30.42.5-0.1-0.0-0.50.50.3-0.6-0.0-0.20.10.10.3-0.30.3-1.51.6-0.4
Patch foraging water rate 6 sec1.31.94.11.1-1.3-1.71.71.30.0-1.21.2-1.31.31.3-1.51.5-2.02.00.5
Seeking ratio, delayed vs. immediate footshock1.61.94.51.2-1.0-1.61.51.41.0-1.11.1-1.11.21.3-1.31.3-2.12.10.8
Distance traveled before self-admin0.10.10.80.00.30.1-0.20.20.90.3-0.10.30.20.10.00.00.10.2-0.2
Distance traveled after self-admin3.94.36.42.3-2.2-2.12.12.32.5-2.12.1-2.12.12.0-1.81.9-2.01.72.0
Extensor digitorum longus weight0.20.61.7-0.80.80.8-1.0-1.1-0.60.9-0.70.8-0.3-0.20.6-0.61.2-1.3-0.4
Bone: elastic displacement0.00.00.3-0.1-0.00.1-0.2-0.1-0.10.2-0.00.00.10.1-0.00.00.5-0.5-0.0
Bone: elastic work1.72.13.01.5-1.5-1.61.41.51.5-1.51.5-1.61.51.5-1.71.7-1.00.91.2
Bone: endosteal estimation1.63.54.01.9-1.8-1.92.02.01.8-1.81.9-1.91.81.8-1.91.9-1.71.81.9
Bone: endosteal perimeter1.53.24.01.9-1.8-1.81.92.01.9-1.61.8-1.71.71.7-1.51.5-1.82.01.5
Epididymis fat weight0.10.30.60.2-0.4-0.70.40.3-0.3-0.30.3-0.30.70.7-0.60.6-0.60.5-0.6
Delta time in closed arm before/after self-admin2.52.53.51.5-1.6-1.81.71.51.0-1.71.6-1.71.81.8-1.91.8-1.21.20.8
Delta time in open arm before/after self-admin0.70.71.3-0.70.60.8-0.8-1.0-0.80.6-0.60.7-0.8-0.80.8-0.71.1-1.1-0.6
Diff in mean of infusions in LGA sessions0.40.40.9-0.40.60.7-0.6-0.10.20.9-0.70.7-0.9-0.90.9-0.90.00.2-0.0
Delay discount exponential model param0.60.61.1-0.90.80.9-0.9-0.9-0.90.9-0.80.8-0.3-0.20.3-0.31.1-1.0-0.8
Extinction: sum of active levers before priming3.03.04.01.8-1.9-1.71.61.81.5-1.91.9-2.02.01.9-2.02.0-1.10.61.4
Active lever presses in extinction session 62.12.04.31.7-1.6-1.21.21.52.1-1.51.7-1.61.61.4-1.41.4-0.00.21.1
Bone: final force1.62.53.21.6-1.8-1.71.71.71.3-1.81.6-1.81.51.5-1.51.5-1.41.21.6
Bone: final moment2.03.23.91.8-2.0-1.81.91.91.6-1.91.9-2.01.81.8-1.71.7-1.51.41.9
Food consumed during 24 hour testing period1.01.22.61.0-1.0-1.21.21.20.7-1.10.9-1.00.80.8-1.01.0-1.61.60.8
Glucose0.20.30.8-0.60.50.4-0.7-0.7-0.40.4-0.50.5-0.1-0.10.1-0.10.8-0.9-0.7
Heart weight0.20.31.20.3-0.3-0.60.50.60.1-0.40.4-0.40.50.5-0.50.5-1.11.0-0.7
Delay discount hyperbolic model param0.50.51.2-0.70.60.8-0.8-0.8-0.80.7-0.60.7-0.3-0.20.3-0.31.1-1.0-0.6
Intermittent access intake day 1-15 change2.52.43.71.5-1.6-1.71.51.41.2-1.61.5-1.51.91.8-1.91.8-1.51.50.7
Intermittent access intake escalation2.52.43.51.4-1.5-1.81.51.41.1-1.61.5-1.41.91.8-1.91.8-1.61.60.3
Intermittent access intake escalation 21.71.72.71.4-1.4-1.41.11.31.6-1.41.4-1.31.41.4-1.41.3-1.01.00.6
Intermitt. access day 1 inactive lever presses3.33.55.22.2-2.3-1.82.12.21.8-2.32.2-2.21.41.3-1.41.4-1.51.32.0
Intermitt. access day 15 inactive lever presses0.60.61.21.0-0.9-0.71.11.00.9-0.90.8-0.80.20.2-0.30.2-1.11.10.3
Intermitt. access escalation Index0.20.20.5-0.40.50.2-0.2-0.2-0.40.6-0.50.5-0.1-0.10.3-0.2-0.40.5-0.7
Intermittent access day 1 total infusions1.92.24.1-1.81.81.3-1.3-1.3-2.01.7-1.81.7-1.4-1.41.4-1.40.10.0-1.6
Intermittent access day 15 total infusions0.30.31.9-0.20.2-0.30.10.2-0.30.1-0.30.20.10.2-0.20.1-1.31.4-1.1
Intermittent access terminal intake (last 3 days)0.30.41.5-0.40.60.1-0.3-0.1-0.30.5-0.60.6-0.3-0.30.3-0.4-0.91.0-1.2
Intermittent access total infusions0.50.62.1-0.80.90.4-0.6-0.4-0.90.8-0.90.9-0.5-0.50.6-0.6-0.70.7-1.5
Intermittent access day 1 locomotion0.90.92.3-1.11.00.8-0.7-0.6-1.51.0-1.21.0-1.1-1.11.1-1.1-0.40.5-0.5
Intermittent access day 15 total locomotion0.30.31.8-0.20.1-0.20.20.2-0.90.1-0.30.20.10.2-0.20.2-1.21.3-0.6
Intermittent access total locomotion1.01.12.5-1.21.11.0-1.0-0.8-1.61.1-1.21.2-1.1-1.11.1-1.1-0.00.1-0.7
Intermittent access standard deviation5.66.07.72.4-2.4-2.62.52.62.2-2.52.3-2.42.42.4-2.52.4-2.82.81.7
Left kidney weight2.46.610.42.6-2.9-2.82.42.32.2-2.62.9-2.63.13.2-3.23.2-1.31.01.5
Right kidney weight4.412.416.73.7-3.9-3.83.33.33.5-3.53.9-3.73.94.0-4.14.1-2.21.82.5
Cocaine induced anxiety0.40.51.30.8-0.9-0.70.60.80.9-0.80.9-0.80.50.5-0.60.5-0.30.31.1
Post-drug Anxiety0.20.20.60.2-0.10.3-0.3-0.10.8-0.00.00.0-0.7-0.70.6-0.70.6-0.70.6
Baseline Anxiety1.11.22.2-1.01.01.1-1.0-1.1-0.81.0-1.11.0-1.4-1.41.4-1.50.8-0.7-0.6
Tail length4.513.718.44.1-4.0-3.83.73.74.3-3.94.1-4.03.83.8-3.93.9-2.62.32.9
Length with tail7.728.332.25.6-5.6-5.65.35.45.6-5.55.6-5.55.75.6-5.55.5-4.34.14.5
Length without tail5.311.614.63.4-3.5-3.73.53.42.7-3.53.3-3.43.83.8-3.53.5-3.23.13.1
Times rat made contact with spout0.70.82.6-1.11.00.6-1.1-1.1-1.20.1-0.90.7-0.2-0.20.1-0.11.1-1.2-1.6
Lifetime Intake0.60.72.3-1.01.00.6-0.8-0.7-1.20.9-1.01.0-0.6-0.50.6-0.6-0.30.3-1.5
Liver weight, left0.50.82.2-0.80.60.8-1.0-1.1-0.90.6-0.70.7-0.6-0.70.7-0.71.4-1.5-0.9
Liver weight, right0.20.41.6-0.20.00.5-0.5-0.6-0.00.4-0.20.3-0.7-0.80.6-0.61.2-1.3-0.0
Locomotor activity0.71.14.6-0.80.81.1-1.2-1.0-0.50.9-0.70.7-0.8-0.80.7-0.72.0-2.1-0.7
Locomotor testing distance0.50.92.4-0.90.80.9-1.0-1.0-0.80.9-0.70.8-0.6-0.60.5-0.51.4-1.6-1.1
Locomotor testing rearing1.92.93.9-1.91.91.7-1.8-2.0-1.71.8-1.81.8-1.3-1.21.5-1.51.6-1.6-1.9
Locomotion in novel chamber0.40.51.1-0.40.50.8-0.7-0.30.10.6-0.40.5-1.0-1.00.8-0.81.1-0.8-0.1
Locomotion in novel chamber post-restriction0.10.20.90.20.10.2-0.10.40.9-0.10.2-0.0-0.6-0.50.2-0.20.20.00.7
Fecal boli incidents, locomotor time 12.62.84.0-1.51.51.9-1.9-1.3-1.01.8-1.41.6-1.9-2.01.9-1.81.9-1.7-1.5
Change in fecal boli incidents, locomotor task0.30.32.00.5-0.6-0.10.20.10.7-0.50.5-0.50.10.0-0.20.10.5-0.61.4
Time >=10cm from walls, locomotor time 10.00.00.1-0.20.10.3-0.2-0.2-0.3-0.20.0-0.0-0.2-0.30.2-0.10.2-0.30.1
Bouts of movement, locomotor time 10.70.82.50.7-0.5-0.70.71.11.2-0.60.5-0.60.80.7-0.70.6-1.61.60.2
Total resting periods, locomotor time 10.60.61.90.7-0.4-0.60.61.11.4-0.50.4-0.60.60.5-0.50.5-1.41.40.3
Rest time, locomotor task time 11.21.32.3-1.01.31.3-1.3-0.9-0.01.3-1.11.0-1.3-1.51.2-1.21.2-1.1-0.5
Distance moved, locomotor task time 10.20.20.60.2-0.1-0.40.60.0-0.3-0.10.1-0.00.80.7-0.40.3-0.60.6-0.2
Vertical activity count, locomotor time 12.12.23.91.5-1.7-1.72.01.40.6-1.61.5-1.41.51.6-1.41.4-1.61.61.2
Time >=10cm from walls, locomotor time 21.81.92.8-1.21.41.6-1.5-1.2-0.61.4-1.41.4-1.6-1.71.6-1.61.2-1.0-0.7
Bouts of movement, locomotor time 20.00.00.1-0.10.2-0.0-0.20.00.3-0.1-0.10.00.20.2-0.10.1-0.40.2-0.3
Total resting periods, locomotor time 20.00.00.1-0.20.20.2-0.3-0.10.20.1-0.20.1-0.1-0.10.2-0.2-0.0-0.1-0.2
Rest time, locomotor task time 20.60.61.4-0.60.70.9-0.8-0.6-0.20.6-0.60.6-1.0-1.21.0-1.01.0-0.9-0.6
Distance moved, locomotor task time 20.10.10.3-0.20.4-0.10.2-0.4-0.40.3-0.40.30.30.3-0.20.2-0.50.5-0.0
Vertical activity count, locomotor time 21.01.12.11.0-0.9-1.21.30.90.7-0.90.8-0.91.11.2-1.11.0-1.51.41.0
Light reinforcement 10.10.10.7-0.40.30.3-0.2-0.3-0.90.3-0.40.3-0.3-0.20.4-0.4-0.00.10.6
Light reinforcement 22.63.54.6-2.01.92.0-1.9-1.9-2.11.8-1.81.8-2.2-2.01.9-1.91.7-1.5-1.4
Bone: marrow area1.63.64.11.9-1.9-2.02.02.01.8-1.81.9-2.01.81.8-1.91.9-1.71.81.9
Bone: maximum diameter1.42.63.41.8-1.8-1.71.71.61.7-1.61.7-1.71.61.6-1.51.5-1.31.31.5
Bone: maximum force2.64.45.32.1-2.2-2.22.22.21.8-2.32.1-2.32.12.1-2.12.1-1.91.72.0
Bone: maximum moment3.05.25.82.3-2.4-2.42.42.42.1-2.42.3-2.42.32.3-2.22.2-2.11.92.2
Mean time between licks in bursts0.10.10.30.3-0.3-0.00.20.20.30.10.2-0.2-0.4-0.40.2-0.2-0.20.20.5
Mean num. licks in bursts1.01.21.91.1-1.1-1.00.80.91.2-1.21.2-1.21.31.3-1.41.40.1-0.20.5
Cd content in liver0.10.10.4-0.1-0.1-0.30.10.0-0.3-0.20.1-0.20.50.6-0.60.6-0.2-0.0-0.4
Co content in liver0.40.40.7-0.60.50.7-0.5-0.7-0.80.6-0.50.6-0.8-0.70.7-0.70.8-0.70.3
Cu content in liver0.50.60.90.8-0.8-0.90.90.70.5-0.70.7-0.80.80.8-0.90.9-0.90.80.7
Fe content in liver0.00.00.0-0.10.10.1-0.1-0.1-0.10.1-0.10.1-0.2-0.20.2-0.2-0.00.0-0.1
K content in liver0.10.10.40.4-0.4-0.20.30.20.5-0.10.4-0.3-0.3-0.4-0.10.10.00.00.6
Mg content in liver0.60.61.5-0.40.40.8-0.6-0.7-0.40.8-0.50.5-1.2-1.20.8-0.81.1-1.0-0.0
Mn content in liver1.21.33.1-0.90.91.2-1.2-1.2-0.70.8-0.90.9-1.4-1.41.0-1.01.8-1.7-0.6
Na content in liver1.81.92.91.5-1.3-1.41.51.41.7-1.21.4-1.31.31.2-1.21.2-1.61.60.9
Rb content in liver0.10.10.4-0.10.10.10.1-0.0-0.40.3-0.20.2-0.5-0.60.3-0.3-0.30.5-0.1
Se content in liver7.89.510.8-3.23.03.3-3.2-3.2-3.13.0-3.13.0-3.2-3.33.2-3.23.1-2.9-2.2
Sr content in liver0.90.91.3-0.90.81.0-1.0-0.9-0.80.8-0.80.8-1.0-1.00.9-0.91.1-1.1-0.6
Zn content in liver0.10.10.3-0.20.10.3-0.1-0.3-0.40.3-0.20.2-0.5-0.50.4-0.40.3-0.20.4
Bone: minimum diameter3.36.17.52.6-2.6-2.52.72.72.6-2.32.5-2.42.22.2-2.12.1-2.72.72.4
Time in familiar zone, hab. session 10.30.30.80.4-0.4-0.30.20.30.7-0.70.5-0.50.90.9-0.50.50.3-0.40.4
Time in novel zone, hab. session 11.01.02.4-0.90.90.8-0.7-0.8-1.21.1-1.00.9-1.6-1.61.0-1.00.2-0.1-0.8
Total zone transitions, hab. session 10.00.10.3-0.10.20.0-0.00.10.00.2-0.20.20.00.00.1-0.1-0.50.60.2
Total locomotion distance, hab. session 11.01.43.01.4-1.3-1.21.21.41.7-1.11.3-1.20.70.7-1.21.2-1.01.01.0
Locomotion velocity, hab. session 10.50.82.11.1-1.0-0.80.81.11.4-0.81.0-0.90.50.5-0.90.9-0.50.50.8
Time in familiar zone, hab. session 21.81.83.51.7-1.7-1.21.31.51.9-1.51.7-1.60.90.9-1.21.2-0.30.41.6
Time in novel zone, hab. session 21.21.22.1-1.31.41.0-1.1-1.2-1.41.1-1.31.2-0.8-0.80.9-0.90.6-0.7-1.3
Total zone transitions, hab. session 22.83.64.5-2.02.12.0-1.9-1.9-1.72.1-2.02.1-2.1-2.12.0-2.01.3-1.2-1.3
Total locomotion distance, hab. session 20.10.10.6-0.20.30.2-0.2-0.1-0.10.4-0.30.3-0.8-0.80.2-0.2-0.20.2-0.3
Locomotion velocity, hab. session 20.10.20.8-0.40.40.3-0.4-0.3-0.30.5-0.50.5-0.9-0.90.4-0.40.10.0-0.3
Novel to familiar place preference ratio0.20.20.50.5-0.4-0.50.50.40.5-0.40.4-0.40.40.4-0.40.4-0.70.60.6
Novelty place preference0.20.20.50.4-0.3-0.40.50.30.3-0.30.3-0.30.30.3-0.30.3-0.70.60.4
Time in novel zone, NPP test0.10.10.30.1-0.1-0.20.30.10.1-0.00.1-0.10.20.2-0.10.1-0.60.50.2
Total zone transitions, NPP test0.10.10.2-0.50.40.3-0.4-0.3-0.50.4-0.40.4-0.1-0.10.3-0.30.2-0.10.2
Total locomotion distance, NPP test2.12.83.41.8-1.8-1.81.61.81.8-1.81.8-1.71.61.6-1.81.8-1.21.11.6
Locomotion velocity, NPP test2.23.13.91.9-1.9-1.81.71.92.0-1.91.9-1.81.61.6-2.02.0-1.11.01.7
Intraocular pressure0.00.10.3-0.00.20.2-0.00.10.20.2-0.20.2-0.2-0.00.5-0.5-0.40.4-0.0
Delta distance traveled before/after self-admin4.85.27.02.5-2.6-2.32.62.32.0-2.42.4-2.52.22.2-2.02.1-2.11.82.3
Delta ambulatory time before/after self-admin5.46.07.62.5-2.7-2.62.82.41.6-2.72.5-2.62.42.4-2.42.4-2.42.22.3
Parametrial fat weight0.40.96.4-0.30.00.6-0.8-0.9-0.2-0.1-0.10.1-0.4-0.40.3-0.32.2-2.50.1
Pavlov. Cond. lever latency0.20.30.60.4-0.3-0.60.40.40.4-0.40.4-0.40.80.8-0.70.7-0.50.3-0.4
Pavlov. Cond. magazine entry latency0.40.50.8-0.70.70.7-0.8-0.8-0.70.6-0.70.7-0.9-0.90.6-0.60.9-0.9-0.5
Pavlov. Cond. change in total contacts0.30.30.7-0.40.40.5-0.2-0.3-0.50.5-0.50.5-0.8-0.80.7-0.7-0.10.30.5
Pavlov. Cond. index score0.50.71.3-0.70.70.9-0.8-0.8-0.70.7-0.70.7-1.2-1.10.9-0.90.9-0.8-0.0
Pavlov. Cond. latency score0.30.40.9-0.50.50.7-0.5-0.5-0.40.5-0.50.5-1.0-0.90.7-0.70.6-0.50.2
Pavlov. Cond. lever contacts0.10.11.10.3-0.30.20.20.20.3-0.10.2-0.1-0.5-0.40.4-0.40.20.01.0
Pavlov. Cond. magazine entry number0.50.71.10.8-0.8-0.80.90.90.8-0.70.8-0.81.01.0-0.70.7-0.80.80.6
Pavlov. Cond. intertrial magazine entries0.81.01.6-1.01.11.2-1.1-1.0-0.51.2-1.01.1-0.8-0.71.3-1.30.8-0.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.60.81.6-0.80.80.9-0.8-0.9-0.80.8-0.80.8-1.3-1.30.9-0.90.9-0.8-0.1
Pavlov. Cond. response bias0.20.30.8-0.30.30.5-0.5-0.5-0.20.3-0.30.4-0.7-0.70.5-0.50.9-0.90.2
Pavlov. Cond. lever latency5.16.97.7-2.82.72.7-2.7-2.7-2.62.8-2.72.7-2.5-2.52.6-2.62.4-2.3-2.4
Pavlov. Cond. magazine entry latency2.73.24.22.0-1.9-1.81.92.02.1-2.02.0-1.91.41.4-1.71.7-1.51.41.5
Pavlov. Cond. change in total contacts8.611.813.23.6-3.5-3.63.63.63.5-3.43.5-3.43.43.4-3.43.4-3.63.32.7
Pavlov. Cond. index score5.26.78.02.7-2.7-2.72.72.72.6-2.82.6-2.72.42.4-2.72.7-2.52.32.1
Pavlov. Cond. latency score4.96.17.22.6-2.6-2.62.62.62.6-2.72.5-2.62.32.3-2.52.5-2.32.22.1
Pavlov. Cond. lever contacts4.86.58.12.6-2.6-2.72.62.62.5-2.92.5-2.62.52.5-2.62.6-2.62.42.1
Pavlov. Cond. magazine entry number3.94.85.9-2.22.12.4-2.2-2.2-2.22.4-2.22.2-2.3-2.32.4-2.42.1-1.8-1.4
Pavlov. Cond. intertrial magazine entries1.01.32.8-1.21.01.1-1.0-1.2-1.71.4-1.21.1-1.0-1.01.2-1.21.1-0.8-0.1
Pavlov. Cond. lever-magazine prob. diff.5.16.57.82.7-2.6-2.72.62.62.6-2.82.6-2.72.42.4-2.72.7-2.32.12.0
Pavlov. Cond. response bias5.57.48.72.7-2.7-2.92.82.82.6-3.02.6-2.82.72.7-2.82.8-2.92.72.1
Time in closed arm before self-admin2.12.43.4-1.61.81.6-1.5-1.5-1.21.7-1.81.8-1.7-1.71.7-1.60.7-0.6-1.2
Time in closed arm after self-admin0.10.10.50.20.0-0.10.20.50.7-0.10.1-0.1-0.1-0.1-0.0-0.0-0.60.70.6
Time in open arm before self-admin4.34.66.62.2-2.5-2.22.22.21.8-2.62.4-2.52.22.1-2.12.0-1.21.32.4
Time in open arm after self-admin1.11.22.11.1-1.4-1.21.20.80.3-1.41.3-1.31.21.2-1.31.2-0.30.40.8
Bone: periosteal estimation2.04.14.62.1-2.1-2.12.12.12.0-2.12.1-2.12.12.1-1.91.9-1.61.72.1
Bone: periosteal perimeter1.22.14.21.7-1.5-1.31.41.62.1-1.51.6-1.51.41.4-1.21.2-0.91.01.4
Bone: post-yield work2.02.84.61.6-1.6-1.71.91.81.3-1.61.5-1.61.51.5-1.51.5-2.12.11.5
Progressive ratio test 1 active lever presses0.70.73.00.4-0.5-0.90.80.9-0.2-0.50.4-0.50.80.8-0.80.7-1.61.70.3
Progressive ratio test 1 breakpoint1.01.03.00.6-0.7-1.11.01.10.1-0.80.7-0.81.01.0-0.90.9-1.61.70.6
Progressive ratio test 1 inactive lever presses0.60.62.40.8-0.7-0.70.91.00.7-0.70.5-0.60.50.4-0.30.3-1.61.50.3
Progressive ratio test 2 active lever presses0.20.21.1-0.00.1-0.30.00.3-0.00.1-0.10.20.30.3-0.30.3-1.01.0-1.1
Progressive ratio test 2 breakpoint0.20.20.9-0.20.2-0.1-0.10.2-0.20.2-0.20.20.20.2-0.20.2-0.90.9-0.9
Progressive ratio test 2 inactive lever presses1.01.25.11.0-0.7-0.81.01.51.3-0.60.6-0.60.40.4-0.30.3-2.22.30.5
Incentive Sensitization - Responses0.20.22.7-0.30.40.2-0.4-0.1-0.10.4-0.40.50.10.0-0.00.1-0.30.3-1.7
Incentive Sensitization - Breakpoint0.20.22.8-0.30.30.2-0.4-0.1-0.20.4-0.40.50.10.1-0.10.2-0.30.3-1.7
Sum of active levers in priming session hrs 5-60.10.10.30.2-0.3-0.30.30.40.1-0.20.3-0.30.50.3-0.30.3-0.30.3-0.1
Progressive ratio0.00.00.00.1-0.10.00.00.2-0.0-0.00.1-0.1-0.2-0.2-0.1-0.00.10.00.2
Food seeking constrained by brief footshock2.93.64.72.1-2.0-1.92.02.22.1-2.02.1-2.01.71.7-1.81.9-1.51.51.5
Seeking ratio, punishment vs. effort0.60.81.10.9-0.8-0.91.00.91.0-0.90.8-0.90.80.8-0.60.8-1.11.00.9
Retroperitoneal fat weight1.65.19.2-2.32.22.3-2.5-2.6-2.21.9-2.12.1-1.6-1.72.0-2.02.7-3.0-2.2
Reaction time number correct0.10.10.6-0.30.10.0-0.2-0.3-0.8-0.0-0.20.10.10.1-0.10.00.1-0.3-0.5
Reaction time mean minus median0.60.82.10.9-1.0-0.91.00.70.4-0.90.9-1.00.80.8-0.80.7-0.60.71.4
Reaction time mean minus median AUC1.21.52.71.2-1.4-1.41.40.90.5-1.41.2-1.31.31.3-1.31.2-0.80.91.6
Reaction time num false alarms0.81.12.1-1.21.11.0-1.0-1.2-1.41.2-1.11.1-0.8-0.91.0-0.90.6-0.7-1.3
Reaction time num false alarms AUC1.01.42.6-1.31.21.1-1.2-1.2-1.61.2-1.21.2-1.1-1.11.1-1.10.8-0.9-1.3
Reaction time trials correct on left0.10.10.6-0.30.10.0-0.2-0.3-0.8-0.0-0.20.10.10.1-0.10.00.1-0.3-0.5
Reaction time trials on left0.10.10.6-0.30.10.0-0.2-0.4-0.80.0-0.20.10.10.1-0.10.00.2-0.3-0.5
Reaction time mean0.20.30.70.3-0.4-0.70.60.3-0.2-0.70.4-0.50.80.8-0.80.7-0.60.7-0.0
Reaction time mean AUC0.20.20.50.2-0.4-0.50.50.2-0.4-0.60.3-0.40.60.6-0.70.5-0.40.50.1
Median of all reaction times0.10.10.30.0-0.1-0.30.20.1-0.5-0.30.1-0.20.50.6-0.60.4-0.40.5-0.6
Reaction time omissions0.00.10.2-0.0-0.1-0.0-0.0-0.3-0.40.20.0-0.0-0.0-0.0-0.10.10.5-0.4-0.3
Reaction time false alarm rate0.50.71.0-0.91.00.9-0.8-0.8-1.01.0-0.90.9-0.8-0.90.9-0.80.5-0.5-0.8
Reaction time premature initiation rate0.10.20.90.4-0.3-0.40.60.50.3-0.20.2-0.2-0.3-0.2-0.20.2-0.70.90.4
Reaction time premature initiations0.10.10.50.1-0.2-0.40.40.3-0.1-0.10.0-0.1-0.2-0.1-0.20.1-0.60.70.0
Std. dev. reaction times0.91.31.71.0-1.1-1.31.30.80.2-1.11.0-1.11.31.3-1.31.1-1.21.31.2
Reaction time trials completed0.10.10.6-0.30.10.0-0.2-0.4-0.80.0-0.20.10.10.1-0.10.00.2-0.3-0.5
Reaction time trials AUC0.10.10.8-0.40.20.2-0.3-0.5-0.90.1-0.30.20.00.10.0-0.10.4-0.6-0.6
Run reversals in cocaine runway, females0.70.71.50.4-0.6-0.90.90.6-0.5-0.70.6-0.71.21.2-1.00.9-1.10.9-0.2
Run reversals in cocaine runway, males0.60.53.8-0.2-0.20.4-0.6-0.7-0.4-0.20.2-0.1-0.5-0.50.1-0.11.7-2.00.1
Latency to leave start box in cocaine runway0.30.31.30.1-0.3-0.60.60.3-0.6-0.10.0-0.10.60.7-0.60.7-1.01.1-0.4
Latency to leave start box in cocaine runway, F0.10.10.7-0.1-0.1-0.30.3-0.0-0.9-0.1-0.20.00.20.2-0.20.2-0.60.7-0.4
Latency to leave start box in cocaine runway, M0.10.10.30.1-0.0-0.20.20.10.10.2-0.00.10.40.5-0.40.4-0.30.3-0.3
Std. dev. time between licks in bursts0.60.81.81.0-0.9-0.51.01.01.3-0.10.8-0.6-0.3-0.30.2-0.2-1.21.41.3
Total sessions with >9 infusions1.11.22.9-1.31.01.0-1.2-1.2-1.71.1-1.21.2-0.9-0.91.0-1.00.8-1.0-1.0
Short access day 1 total inactive lever presses0.40.52.60.5-0.2-0.40.60.80.7-0.20.2-0.2-0.00.0-0.20.2-1.61.60.5
Short access day 10 total inactive lever presses1.41.52.71.4-1.3-1.11.41.61.6-1.11.3-1.20.90.8-0.80.9-1.31.60.7
Short access day 1 total infusions0.10.10.2-0.40.40.3-0.3-0.3-0.40.4-0.40.4-0.2-0.10.3-0.3-0.10.1-0.2
Short access day 10 total infusions0.50.52.4-1.00.70.5-0.7-0.7-1.60.7-0.80.8-0.5-0.40.4-0.40.1-0.1-1.0
Short access total infusions1.01.12.6-1.31.11.0-1.2-1.1-1.61.1-1.11.2-0.8-0.70.8-0.80.6-0.7-1.2
Short access day 1 locomotion0.40.42.8-0.80.40.5-0.5-0.7-1.70.3-0.60.4-0.5-0.40.5-0.50.3-0.40.5
Short access day 10 total locomotion0.80.93.10.7-1.0-1.01.01.10.1-0.90.8-0.90.40.5-0.70.6-1.41.41.8
Short access total locomotion0.90.92.4-1.10.80.9-0.9-0.8-1.60.8-0.90.9-1.1-1.11.0-1.00.5-0.60.5
One hour access (0.3 mA shock)1.21.44.21.0-1.0-1.41.21.40.7-1.00.9-1.01.11.1-1.01.0-2.01.90.2
Compulsive drug intake0.10.11.30.5-0.2-0.20.20.21.1-0.10.2-0.10.20.1-0.00.2-0.10.1-0.3
One hour access (shock baseline)0.10.21.1-0.0-0.1-0.40.20.4-0.4-0.1-0.0-0.10.10.2-0.20.1-1.11.0-0.1
Social response proportion2.02.23.41.7-1.7-1.41.61.81.8-1.51.6-1.60.90.9-1.11.1-1.31.31.9
Social responses0.81.05.91.2-1.2-0.61.11.21.1-0.81.1-1.10.10.1-0.00.1-0.30.62.4
Social time3.03.96.71.8-1.9-2.12.22.11.3-2.01.8-2.01.81.9-1.91.8-2.32.61.8
Soleus weight0.10.41.3-0.70.40.6-0.5-0.7-1.20.6-0.60.5-0.5-0.40.6-0.60.8-0.70.1
Bone: stiffness1.32.12.61.4-1.5-1.51.51.51.4-1.61.4-1.51.31.3-1.51.5-1.41.31.3
Tibialis anterior weight0.10.31.3-0.40.40.5-0.6-0.7-0.20.3-0.30.40.20.30.2-0.21.1-1.20.1
Time to tail flick, vehicle, before self-admin0.91.01.4-1.11.00.9-0.9-0.9-1.01.1-1.11.1-0.9-1.00.8-1.00.7-0.5-1.2
Time to tail flick, vehicle, after self-admin0.20.21.10.3-0.10.2-0.10.21.10.00.2-0.1-0.4-0.50.4-0.40.3-0.20.6
Time to tail flick, test, before self-admin0.40.41.7-0.60.6-0.1-0.1-0.4-1.20.4-0.70.60.1-0.0-0.00.1-1.00.8-1.3
Time to tail flick, test, after self-admin0.00.00.2-0.1-0.1-0.1-0.0-0.1-0.4-0.0-0.2-0.00.20.0-0.10.1-0.20.00.4
Delta time to tail flick, vehicle, before/after SA0.80.82.51.1-1.0-0.80.80.91.2-0.91.0-1.00.60.6-0.50.6-0.60.41.6
Delta time to tail flick, test, before/after SA0.60.52.3-0.30.10.7-0.7-0.50.00.3-0.20.2-0.6-0.60.7-0.71.5-1.50.7
Tibia length2.98.111.42.6-2.7-3.22.82.72.1-3.12.7-2.93.33.2-3.43.4-2.72.41.8
Ambulatory time before self-admin0.10.10.4-0.10.40.3-0.30.10.60.3-0.10.3-0.1-0.20.3-0.30.2-0.00.2
Ambulatory time after self-admin7.38.010.02.9-2.9-2.92.93.22.8-2.92.8-2.92.82.7-2.72.7-2.82.62.5
Bone: tissue strength3.83.75.01.9-2.0-2.12.12.01.4-2.11.9-2.01.71.7-1.81.8-2.22.11.6
Total heroin consumption0.30.40.90.6-0.5-0.70.61.00.8-0.40.5-0.50.60.4-0.70.6-0.80.90.4
Bone: trabecular number1.42.33.11.4-1.5-1.71.51.40.9-1.61.4-1.61.61.6-1.81.8-1.41.11.4
Bone: trabecular spacing0.20.31.30.7-0.6-0.30.40.41.2-0.40.7-0.50.10.1-0.40.40.2-0.20.1
Bone: trabecular thickness0.10.10.4-0.40.30.0-0.2-0.4-0.70.2-0.30.30.30.3-0.10.1-0.1-0.1-0.4
Bone: trabecular tissue density2.73.97.5-2.02.02.1-2.3-2.2-1.41.7-1.81.9-1.4-1.41.7-1.72.7-2.7-1.8
Water consumed over 24 hours0.40.50.90.6-0.7-0.80.70.60.4-0.90.6-0.80.80.8-0.90.9-0.70.60.4
Number of responses in last shaping day0.20.21.1-0.10.30.1-0.00.20.40.5-0.30.4-0.3-0.20.2-0.2-0.81.10.9