Hub : Genes

Tatdn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr7_92351358_92355774 0.03 0.03 4.0e-03 0.02 0.02 0.03 0.02 1.9e-03 1.9e-03 7.9e-04 3.8e-03
2 Brain alternative TSS XM_039080195.2 0.05 0.05 7.9e-05 0.03 0.04 0.05 0.04 3.5e-04 1.8e-04 1.7e-05 2.9e-04
3 PL intron excision ratio chr7_92357025_92358011 0.12 0.11 5.7e-11 0.1 0.1 0.11 0.1 1.6e-10 2.0e-11 1.2e-11 1.5e-11
4 pVTA intron excision ratio chr7_92351358_92355774 0.32 0.24 9.8e-06 0.07 0.07 0.07 0.07 3.4e-06 1.3e-06 2.8e-06 4.2e-06
5 NAcc intron excision ratio chr7_92357025_92358011 0.07 0.05 5.3e-11 0.08 0.07 0.07 0.07 1.2e-11 2.3e-11 5.0e-11 5.7e-11
6 pVTA isoform ratio NM_001400945.1 0.04 0.04 1.3e-03 0.03 0.03 0.03 0.03 1.5e-03 2.7e-03 3.3e-03 3.9e-03
7 NAcc mRNA stability Tatdn1 0.02 0.02 2.4e-03 0.01 0.01 0.01 0.01 4.0e-03 1.2e-02 1.8e-03 4.5e-03
8 IC intron excision ratio chr7_92351358_92355774 0.09 0.09 1.0e-03 0.08 0.07 0.07 0.07 2.6e-04 7.3e-04 5.9e-04 6.4e-04
9 Liver mRNA stability Tatdn1 0.02 0.02 6.4e-03 0.02 0.01 0.01 0.01 5.4e-03 1.7e-02 8.2e-03 1.3e-02
10 PL intron excision ratio chr7_92356052_92358011 0.08 0.07 4.2e-08 0.08 0.07 0.08 0.08 1.1e-08 3.5e-08 3.1e-09 5.5e-09
11 pVTA intron excision ratio chr7_92356052_92358011 0.05 0.05 8.5e-04 0.03 0.03 0.03 0.03 2.7e-03 1.1e-03 8.6e-04 1.1e-03
12 Adipose mRNA stability Tatdn1 0.06 0.07 7.3e-06 0.05 0.05 0.05 0.05 2.9e-06 4.3e-06 3.0e-06 2.6e-06
13 pVTA intron excision ratio chr7_92357025_92358011 0.1 0.08 6.4e-08 0.08 0.1 0.09 0.08 3.1e-07 4.9e-08 2.5e-07 2.7e-07
14 Liver gene expression Tatdn1 0.04 0.04 7.0e-06 0.04 0.04 0.04 0.04 5.5e-05 1.2e-05 1.6e-05 2.8e-05
15 PL gene expression Tatdn1 0.03 0.03 2.0e-03 0.01 0.02 0.01 0.01 1.1e-02 1.6e-03 1.3e-02 7.7e-03
16 RMTg alternative TSS XM_039080192.2 0.28 0.24 1.9e-04 0.05 0.09 0.05 0.06 1.7e-02 2.9e-03 1.5e-02 1.5e-02
17 OFC gene expression Tatdn1 0.19 0.17 2.4e-03 0.05 0.08 0.03 0.04 2.3e-02 7.4e-03 5.7e-02 3.6e-02
18 IL alternative TSS XM_039080187.2 0.19 0.17 2.3e-03 0.04 0.09 0.04 0.03 4.6e-02 3.0e-03 4.3e-02 5.4e-02
19 NAcc alternative TSS XM_039080195.2 0.03 0.03 4.8e-05 0.03 0.03 0.03 0.03 4.4e-05 3.0e-05 5.6e-05 5.7e-05
20 Adipose gene expression Tatdn1 0.02 0.02 3.6e-03 0.01 0.02 0.01 0.01 7.3e-03 5.2e-03 1.2e-02 1.1e-02
21 Adipose isoform ratio XR_010053043.1 0.02 0.02 7.7e-03 0.01 0.01 0.01 0.01 2.6e-02 1.3e-02 4.0e-02 2.2e-02
22 NAcc intron excision ratio chr7_92356052_92358011 0.04 0.03 5.4e-06 0.03 0.03 0.03 0.03 8.5e-06 6.9e-06 1.1e-05 1.1e-05
23 BLA gene expression Tatdn1 0.1 0.1 1.3e-04 0.07 0.07 0.07 0.06 1.3e-04 1.8e-04 2.3e-04 3.4e-04
24 NAcc intron excision ratio chr7_92351358_92355774 0.04 0.04 3.2e-06 0.04 0.04 0.04 0.04 1.3e-06 2.6e-06 3.5e-06 4.2e-06
25 Brain intron excision ratio chr7_92351358_92355774 0.03 0.03 4.3e-03 0.02 0.02 0.01 0.02 3.7e-03 4.5e-03 3.2e-02 1.1e-02
26 LHb gene expression Tatdn1 0.21 0.18 1.9e-03 0.1 0.09 0.07 0.09 3.0e-03 3.0e-03 8.3e-03 4.5e-03
27 PL isoform ratio XM_039080195.2 0.02 0.02 8.6e-03 0.03 0.01 0.03 0.03 2.3e-04 1.7e-02 6.3e-04 6.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.61.11.5-1.21.21.21.21.1-1.1-1.1-0.9-1.1-1.0-1.11.0-1.11.1-1.11.1-1.11.1-1.11.11.11.11.2-1.2-1.20.00.0
Area under the delay curve0.10.20.3-0.0-0.5-0.5-0.4-0.40.30.40.50.40.50.5-0.40.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.40.40.40.00.0
BMI with tail4.014.018.0-4.24.14.04.04.0-4.0-4.0-3.7-3.8-3.7-3.93.8-3.93.8-3.83.9-3.83.8-3.83.83.83.83.8-3.8-3.90.00.0
BMI without tail0.52.94.4-2.01.91.82.11.9-1.9-1.9-1.6-1.7-1.6-1.61.6-1.81.7-1.71.8-1.71.7-1.71.71.71.71.8-1.8-1.80.00.0
Body weight2.19.011.6-3.33.33.23.43.2-3.2-3.2-2.9-3.1-2.9-3.13.0-3.13.1-3.13.1-3.13.1-3.13.13.13.13.1-3.1-3.20.00.0
Weight adjusted by age0.41.12.31.21.11.01.51.2-1.1-1.1-0.8-1.2-0.9-0.91.1-1.11.0-1.01.1-1.01.0-1.01.01.01.11.0-1.0-1.20.00.0
Bone surface0.00.00.20.4-0.2-0.2-0.1-0.20.20.20.30.20.20.2-0.20.2-0.20.2-0.20.2-0.20.2-0.2-0.2-0.2-0.00.00.10.00.0
Bone volume0.10.10.20.5-0.4-0.4-0.3-0.40.40.40.50.40.40.4-0.40.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.30.30.30.00.0
Breakpoint value in progressive ratio session0.71.31.71.2-1.3-1.3-1.1-1.01.01.01.31.21.21.2-1.21.2-1.21.2-1.21.2-1.21.2-1.2-1.2-1.2-1.11.11.10.00.0
Number of licking bursts0.51.62.10.3-1.4-1.4-1.3-1.31.31.31.41.31.41.3-1.31.3-1.31.3-1.31.3-1.31.3-1.3-1.3-1.3-1.31.31.30.00.0
Context. condit. distance diff. score0.70.84.3-2.10.81.00.80.9-0.9-0.9-0.8-0.7-0.8-1.00.7-0.80.9-0.90.9-0.90.9-0.90.90.90.90.8-0.8-0.80.00.0
Locomotion velocity, session 10.00.00.4-0.70.20.20.00.2-0.3-0.3-0.3-0.1-0.3-0.20.2-0.20.2-0.20.2-0.20.2-0.20.20.20.20.1-0.1-0.10.00.0
Locomotion distance, session 10.10.10.6-0.80.40.30.40.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.30.3-0.30.3-0.30.3-0.30.30.30.30.3-0.3-0.40.00.0
Locomotion velocity, session 20.80.91.2-0.71.11.10.90.9-1.0-1.0-1.1-1.0-1.1-1.01.1-1.01.0-1.01.0-1.01.0-1.01.01.01.00.9-0.9-1.00.00.0
Locomotion distance, session 20.10.10.30.60.30.30.30.2-0.2-0.2-0.3-0.3-0.3-0.20.3-0.30.3-0.30.3-0.30.3-0.30.30.20.30.3-0.3-0.30.00.0
Locomotion velocity, session 30.50.60.80.3-0.9-0.9-0.8-0.80.80.80.80.80.90.8-0.80.8-0.80.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.80.80.00.0
Locomotion distance, session 30.30.30.4-0.6-0.7-0.6-0.6-0.50.50.50.60.60.70.5-0.60.6-0.60.6-0.50.6-0.60.6-0.6-0.5-0.6-0.60.60.60.00.0
Stereotopy head waving bouts, day 31.11.31.90.31.41.31.21.1-1.1-1.1-1.2-1.3-1.3-1.11.3-1.21.2-1.21.2-1.21.2-1.21.21.21.21.3-1.3-1.20.00.0
Stereotopy head waving duration, day 30.10.21.31.20.40.30.40.2-0.2-0.2-0.3-0.5-0.4-0.20.4-0.30.3-0.30.3-0.30.3-0.30.30.30.30.4-0.4-0.30.00.0
Locomotion velocity, session 70.91.01.40.3-1.2-1.1-1.0-1.11.01.01.21.11.21.0-1.11.1-1.11.1-1.01.1-1.11.1-1.1-1.1-1.1-1.01.01.00.00.0
Locomotion distance, session 73.74.76.11.7-2.5-2.4-2.2-2.22.22.22.32.42.32.2-2.32.3-2.22.2-2.22.2-2.22.2-2.2-2.2-2.2-2.22.22.20.00.0
Stereotopy head waving bouts, day 70.40.41.21.10.80.70.70.6-0.6-0.6-0.6-0.9-0.7-0.60.8-0.60.6-0.60.6-0.60.6-0.60.60.60.60.6-0.6-0.50.00.0
Stereotopy head waving duration, day 70.10.13.01.70.10.00.1-0.00.00.0-0.0-0.4-0.10.00.2-0.10.0-0.00.0-0.00.0-0.00.00.00.00.0-0.00.00.00.0
Locomotion velocity, session 81.31.62.4-1.51.41.41.31.2-1.2-1.2-1.3-1.3-1.3-1.21.3-1.31.3-1.31.3-1.31.3-1.31.31.31.31.3-1.3-1.30.00.0
Locomotion distance, session 80.00.00.2-0.4-0.00.00.00.0-0.0-0.00.00.10.1-0.0-0.0-0.00.0-0.00.0-0.00.0-0.00.00.00.00.0-0.0-0.10.00.0
Degree of sensitization distance1.21.32.71.6-1.2-1.3-1.1-1.21.21.21.21.21.21.2-1.21.1-1.21.2-1.21.2-1.21.2-1.2-1.2-1.2-1.11.11.10.00.0
Degree of sensitization stereotypy0.20.21.61.3-0.3-0.4-0.3-0.40.40.40.40.10.30.4-0.20.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.40.40.40.00.0
Conditioned locomotion3.23.86.32.5-2.1-2.1-2.0-2.02.02.02.01.92.02.0-1.92.0-2.02.0-2.02.0-2.02.0-2.0-2.0-2.0-2.02.02.00.00.0
Cocaine response after cond. corrected0.00.00.80.9-0.1-0.1-0.00.0-0.0-0.00.10.0-0.0-0.0-0.10.1-0.00.0-0.00.0-0.00.0-0.0-0.0-0.0-0.10.10.10.00.0
Cocaine response after cond. not corrected0.10.10.2-0.00.40.40.40.5-0.5-0.5-0.4-0.4-0.4-0.50.4-0.40.4-0.40.4-0.40.4-0.40.40.40.40.4-0.4-0.40.00.0
Cocaine response before conditioning1.11.45.2-2.31.31.31.21.1-1.1-1.1-1.2-1.1-1.1-1.11.1-1.21.1-1.11.1-1.11.1-1.11.11.11.21.2-1.2-1.20.00.0
Saline control response0.00.00.9-1.00.20.10.10.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.10.1-0.10.10.10.10.2-0.2-0.10.00.0
Bone: connectivity density0.40.61.0-0.50.90.91.00.8-0.8-0.8-0.7-0.8-0.7-0.80.8-0.90.8-0.80.8-0.80.8-0.80.80.80.81.0-1.0-0.90.00.0
Bone: cortical apparent density2.13.34.30.7-2.1-2.0-1.9-1.91.91.92.02.02.01.9-2.01.9-1.91.9-1.91.9-1.91.9-1.9-1.9-1.9-1.81.81.90.00.0
Bone: cortical area0.00.00.70.9-0.1-0.1-0.00.0-0.0-0.00.1-0.10.0-0.00.00.0-0.00.0-0.00.0-0.00.0-0.0-0.0-0.0-0.10.10.10.00.0
Bone: cortical porosity0.70.81.3-0.31.01.00.90.9-0.9-0.9-1.0-1.1-1.0-0.91.1-0.90.9-0.90.9-0.90.9-0.90.90.90.90.8-0.8-0.90.00.0
Bone: cortical porosity0.80.91.3-0.51.11.11.00.9-0.9-0.9-1.1-1.2-1.1-0.91.1-1.01.0-1.01.0-1.01.0-1.01.01.01.00.9-0.9-1.00.00.0
Bone: cortical thickness0.30.50.7-0.10.80.70.70.8-0.8-0.8-0.6-0.8-0.7-0.80.8-0.70.7-0.70.7-0.70.7-0.70.70.70.70.7-0.7-0.60.00.0
Bone: cortical thickness0.10.22.31.50.40.30.40.3-0.3-0.3-0.2-0.4-0.3-0.30.3-0.30.3-0.30.3-0.30.3-0.30.30.30.30.3-0.3-0.20.00.0
Bone: cortical tissue density2.13.44.40.7-2.1-2.1-1.9-1.91.91.92.02.12.01.9-2.01.9-1.91.9-1.91.9-1.91.9-1.9-1.9-1.9-1.91.92.00.00.0
Condit. Reinf. active minus inactive responses0.30.41.3-1.10.60.70.60.6-0.7-0.7-0.6-0.5-0.6-0.70.5-0.60.6-0.60.6-0.60.6-0.60.60.60.60.6-0.6-0.60.00.0
Condit. Reinf. active-inactive response ratio0.30.30.7-0.80.60.60.50.6-0.6-0.6-0.5-0.6-0.5-0.60.6-0.50.6-0.60.6-0.60.6-0.60.60.60.50.5-0.5-0.50.00.0
Condit. Reinf. active responses0.50.62.5-1.60.80.80.80.8-0.9-0.9-0.8-0.6-0.7-0.80.7-0.80.8-0.80.8-0.80.8-0.80.80.80.80.8-0.8-0.80.00.0
Condit. Reinf. inactive responses0.20.31.8-1.30.50.60.50.6-0.6-0.6-0.5-0.3-0.5-0.50.4-0.50.5-0.50.5-0.50.5-0.50.50.50.50.6-0.6-0.60.00.0
Incentive salience index mean0.10.10.4-0.60.30.40.40.4-0.4-0.4-0.3-0.3-0.3-0.40.3-0.40.4-0.30.4-0.30.3-0.30.30.40.30.4-0.4-0.40.00.0
Condit. Reinf. lever presses0.00.00.00.2-0.1-0.1-0.0-0.10.10.10.20.20.20.1-0.20.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.1-0.00.00.00.00.0
Condit. Reinf. active minus inactive responses1.21.82.8-1.71.51.51.41.4-1.4-1.4-1.4-1.3-1.4-1.41.3-1.41.4-1.41.4-1.41.4-1.41.41.41.41.4-1.4-1.40.00.0
Condit. Reinf. active-inactive response ratio0.10.20.7-0.80.50.50.50.5-0.5-0.5-0.4-0.5-0.4-0.50.4-0.50.5-0.50.5-0.50.5-0.50.50.50.50.5-0.5-0.50.00.0
Condit. Reinf. active responses1.92.73.3-1.61.81.81.71.7-1.7-1.7-1.7-1.7-1.7-1.71.7-1.71.7-1.71.7-1.71.7-1.71.71.71.71.7-1.7-1.70.00.0
Condit. Reinf. inactive responses0.50.81.0-0.21.01.00.91.0-1.0-1.0-1.0-0.9-1.0-1.01.0-0.91.0-1.00.9-1.01.0-0.91.01.00.90.9-0.9-0.90.00.0
Condit. Reinf. lever presses1.11.72.20.31.51.41.41.4-1.3-1.3-1.3-1.4-1.4-1.41.4-1.41.3-1.31.4-1.31.3-1.31.31.31.31.4-1.4-1.40.00.0
Condit. Reinf. lever reinforcers received1.52.12.6-1.21.61.61.51.5-1.5-1.5-1.5-1.5-1.5-1.51.5-1.51.5-1.51.5-1.51.5-1.51.51.51.51.5-1.5-1.50.00.0
Conditioned reinforcement - actives0.20.82.5-0.01.00.81.61.0-1.1-1.1-0.6-1.0-0.7-0.60.9-1.00.9-0.91.0-0.90.9-0.90.90.90.91.1-1.1-1.10.00.0
Conditioned reinforcement - inactives0.20.62.11.5-0.7-0.9-0.2-0.80.80.81.00.60.90.9-0.70.6-0.70.8-0.70.7-0.70.8-0.8-0.7-0.7-0.50.50.50.00.0
Conditioned locomotion0.50.72.40.90.90.71.51.0-1.0-1.0-0.6-1.0-0.6-0.50.8-0.90.8-0.80.9-0.80.8-0.80.80.80.81.0-1.0-1.00.00.0
Patch foraging indifference point 0 sec0.20.71.00.10.90.90.80.9-0.9-0.8-0.9-1.0-1.0-0.80.9-0.90.9-0.90.9-0.90.9-0.90.90.90.90.9-0.9-0.90.00.0
Patch foraging indifference point AUC0.10.31.91.4-0.6-0.6-0.6-0.50.50.50.40.60.50.5-0.60.6-0.50.5-0.50.5-0.50.5-0.5-0.5-0.5-0.60.60.60.00.0
Delay disc. indifference point, 0s delay0.10.12.9-1.70.0-0.00.2-0.10.00.00.10.00.10.1-0.0-0.0-0.00.00.00.0-0.00.0-0.0-0.00.00.1-0.1-0.10.00.0
Delay disc. indifference point, 16s delay1.62.23.81.9-1.7-1.6-1.6-1.51.51.41.51.51.51.5-1.51.5-1.51.5-1.51.5-1.51.5-1.5-1.5-1.5-1.51.51.60.00.0
Delay disc. indifference point, 2s delay0.91.02.5-1.61.11.01.11.0-1.0-1.0-1.0-1.0-0.9-1.01.0-1.01.0-1.01.0-1.01.0-1.01.01.01.01.1-1.1-1.10.00.0
Delay disc. indifference point, 24s delay0.00.00.10.2-0.2-0.2-0.1-0.10.10.10.20.10.20.2-0.10.2-0.20.2-0.20.2-0.20.2-0.2-0.2-0.2-0.10.10.20.00.0
Delay disc. indifference point, 4s delay0.40.41.5-1.20.60.60.80.5-0.6-0.6-0.5-0.7-0.5-0.50.6-0.60.6-0.60.6-0.60.6-0.60.60.60.60.7-0.7-0.60.00.0
Delay disc. indifference point, 8s delay0.30.60.90.1-1.0-0.9-0.8-0.70.70.70.80.80.80.8-0.80.8-0.80.8-0.80.8-0.80.8-0.8-0.8-0.8-0.90.90.80.00.0
Indifference point function ln k0.82.33.90.11.71.62.01.5-1.5-1.5-1.4-1.7-1.5-1.41.6-1.61.5-1.51.6-1.51.5-1.51.51.51.61.7-1.7-1.70.00.0
Indifference point function log k0.82.33.90.11.71.62.01.5-1.5-1.5-1.4-1.7-1.5-1.41.6-1.61.5-1.51.6-1.51.5-1.51.51.51.61.7-1.7-1.70.00.0
Patch foraging total patch changes 0 sec0.10.30.40.40.50.50.50.5-0.5-0.5-0.5-0.6-0.6-0.50.6-0.50.5-0.50.5-0.50.5-0.50.50.50.50.5-0.5-0.50.00.0
Patch foraging total patch changes 12 sec1.11.42.20.9-1.4-1.3-1.5-1.21.21.21.11.41.11.2-1.31.3-1.21.2-1.31.2-1.21.2-1.2-1.2-1.2-1.31.31.30.00.0
Patch foraging total patch changes 18 sec0.00.10.3-0.50.30.30.10.3-0.3-0.3-0.4-0.2-0.4-0.40.3-0.20.3-0.30.3-0.30.3-0.30.30.30.30.2-0.2-0.20.00.0
Patch foraging total patch changes 24 sec0.20.62.10.3-1.0-0.8-1.5-0.70.70.70.51.00.60.5-0.80.9-0.80.8-0.90.8-0.80.8-0.8-0.8-0.8-1.01.01.00.00.0
Patch foraging total patch changes 6 sec0.10.20.50.1-0.4-0.4-0.7-0.30.30.30.20.40.30.3-0.40.5-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.50.50.60.00.0
Patch foraging time to switch 0 sec0.20.93.2-1.8-1.0-0.9-1.3-0.90.90.90.81.00.90.9-1.01.0-0.90.9-1.00.9-0.90.9-0.9-0.9-0.9-1.01.01.00.00.0
Patch foraging water rate 0 sec0.62.12.80.41.61.61.71.6-1.6-1.6-1.5-1.7-1.5-1.61.6-1.51.5-1.51.5-1.51.5-1.51.51.51.51.5-1.5-1.50.00.0
Patch foraging water rate 12 sec0.10.30.50.20.60.70.30.6-0.5-0.6-0.7-0.6-0.7-0.70.7-0.60.6-0.60.6-0.60.6-0.60.60.60.60.6-0.6-0.60.00.0
Patch foraging water rate 18 sec0.51.13.0-1.71.11.11.01.0-1.0-1.0-1.0-1.1-1.1-1.01.1-1.01.0-1.01.0-1.01.0-1.01.01.01.01.1-1.1-1.10.00.0
Patch foraging water rate 24 sec0.40.60.8-0.60.90.90.80.8-0.8-0.8-0.8-0.8-0.7-0.80.9-0.80.8-0.80.8-0.80.8-0.80.80.80.80.8-0.8-0.80.00.0
Patch foraging water rate 6 sec1.21.72.81.71.51.31.61.3-1.3-1.3-1.2-1.5-1.4-1.31.5-1.41.3-1.31.3-1.31.3-1.31.31.31.31.4-1.4-1.40.00.0
Seeking ratio, delayed vs. immediate footshock0.00.00.5-0.7-0.2-0.1-0.1-0.1-0.00.00.20.20.30.0-0.20.1-0.20.2-0.20.2-0.20.2-0.2-0.2-0.2-0.00.00.20.00.0
Distance traveled before self-admin0.10.11.51.2-0.3-0.3-0.1-0.40.40.40.30.10.40.4-0.20.3-0.30.3-0.30.3-0.30.3-0.3-0.3-0.3-0.20.20.20.00.0
Distance traveled after self-admin0.10.10.3-0.50.30.30.20.3-0.4-0.4-0.4-0.3-0.3-0.20.4-0.30.3-0.30.3-0.30.3-0.30.30.30.30.3-0.3-0.30.00.0
Extensor digitorum longus weight2.610.519.9-4.53.53.53.33.3-3.3-3.3-3.3-3.1-3.3-3.33.2-3.33.3-3.33.3-3.33.3-3.33.33.33.33.3-3.3-3.40.00.0
Bone: elastic displacement2.93.74.7-1.32.12.21.92.0-2.0-2.0-2.1-2.0-2.1-2.02.0-2.02.0-2.02.0-2.02.0-2.02.02.02.02.0-2.0-2.00.00.0
Bone: elastic work2.02.63.3-1.21.81.81.61.7-1.7-1.7-1.7-1.7-1.7-1.71.7-1.71.7-1.71.7-1.71.7-1.71.71.71.71.6-1.6-1.70.00.0
Bone: endosteal estimation0.81.92.41.3-1.6-1.5-1.5-1.41.41.41.41.51.41.4-1.41.4-1.41.4-1.41.4-1.41.4-1.4-1.4-1.4-1.31.31.40.00.0
Bone: endosteal perimeter0.30.71.91.4-0.9-0.9-0.8-0.80.80.80.80.70.80.8-0.80.8-0.80.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.80.80.00.0
Epididymis fat weight0.00.00.10.1-0.1-0.10.20.0-0.1-0.10.2-0.10.20.1-0.00.0-0.10.1-0.00.1-0.10.1-0.1-0.1-0.1-0.10.10.10.00.0
Delta time in closed arm before/after self-admin0.20.20.6-0.70.50.50.30.2-0.2-0.2-0.6-0.5-0.6-0.40.5-0.40.5-0.50.4-0.50.5-0.50.50.40.50.5-0.5-0.50.00.0
Delta time in open arm before/after self-admin0.70.82.91.7-1.0-1.0-1.0-0.70.70.70.90.70.90.9-0.80.9-0.90.9-0.90.9-0.90.9-0.9-0.9-0.9-1.01.01.00.00.0
Diff in mean of infusions in LGA sessions0.00.11.01.00.20.10.00.1-0.1-0.1-0.1-0.4-0.2-0.20.3-0.10.2-0.20.1-0.20.2-0.20.20.20.10.1-0.1-0.10.00.0
Delay discount exponential model param0.10.10.20.00.50.50.30.4-0.3-0.3-0.4-0.3-0.4-0.40.4-0.40.4-0.40.4-0.40.4-0.40.40.40.40.4-0.4-0.40.00.0
Extinction: sum of active levers before priming1.32.03.31.0-1.5-1.5-1.8-1.61.61.61.31.41.21.4-1.41.5-1.41.4-1.51.4-1.41.4-1.4-1.5-1.5-1.51.51.50.00.0
Active lever presses in extinction session 60.60.61.00.5-0.9-0.9-0.6-0.50.60.51.01.01.00.7-1.00.8-0.80.8-0.80.8-0.80.8-0.8-0.8-0.8-0.70.70.70.00.0
Bone: final force0.91.52.4-1.51.31.31.21.3-1.3-1.3-1.1-1.2-1.2-1.31.2-1.21.2-1.21.3-1.21.2-1.21.21.21.21.3-1.3-1.20.00.0
Bone: final moment0.50.71.8-1.40.90.90.80.9-0.9-0.9-0.8-0.8-0.8-0.90.8-0.80.9-0.90.9-0.90.9-0.90.90.90.80.9-0.9-0.80.00.0
Food consumed during 24 hour testing period0.30.55.9-2.40.60.60.60.6-0.6-0.6-0.6-0.5-0.5-0.60.6-0.60.6-0.60.6-0.60.6-0.60.60.60.60.6-0.6-0.60.00.0
Glucose1.62.53.21.5-1.8-1.8-1.5-1.61.61.61.71.51.81.6-1.61.6-1.61.6-1.61.6-1.61.6-1.6-1.6-1.6-1.61.61.60.00.0
Heart weight0.50.93.8-2.01.00.91.20.9-0.9-0.9-0.8-0.9-0.7-0.80.8-0.90.9-0.90.9-0.90.9-0.90.90.90.91.0-1.0-1.00.00.0
Delay discount hyperbolic model param0.00.00.30.50.20.20.00.1-0.0-0.0-0.2-0.1-0.2-0.20.1-0.10.1-0.10.1-0.10.1-0.10.10.10.10.1-0.1-0.10.00.0
Intermittent access intake day 1-15 change0.21.01.31.1-1.1-1.1-0.9-1.11.11.11.11.00.91.0-1.01.0-1.01.0-1.01.0-1.01.0-1.0-1.0-1.0-1.01.01.00.00.0
Intermittent access intake escalation0.10.50.80.6-0.8-0.9-0.6-0.90.90.90.90.70.70.8-0.80.7-0.80.8-0.70.8-0.80.8-0.8-0.8-0.7-0.70.70.70.00.0
Intermittent access intake escalation 20.10.13.4-1.90.10.10.10.1-0.1-0.1-0.0-0.1-0.1-0.10.0-0.10.1-0.10.1-0.10.1-0.10.10.10.10.1-0.1-0.10.00.0
Intermitt. access day 1 inactive lever presses0.00.00.60.8-0.0-0.20.3-0.30.20.20.3-0.00.20.2-0.10.0-0.10.1-0.00.1-0.10.1-0.1-0.1-0.10.0-0.0-0.00.00.0
Intermitt. access day 15 inactive lever presses0.10.54.82.20.60.31.40.5-0.5-0.5-0.1-0.7-0.2-0.10.5-0.60.4-0.40.6-0.40.4-0.40.40.40.50.7-0.7-0.70.00.0
Intermitt. access escalation Index0.10.20.6-0.80.40.50.30.4-0.4-0.4-0.5-0.4-0.3-0.40.4-0.40.4-0.40.4-0.40.4-0.40.40.40.40.4-0.4-0.40.00.0
Intermittent access day 1 total infusions0.41.22.11.4-1.3-1.2-1.0-1.11.01.01.21.11.31.2-1.21.1-1.21.2-1.11.2-1.21.2-1.2-1.1-1.1-1.11.11.10.00.0
Intermittent access day 15 total infusions0.71.72.20.9-1.5-1.5-1.3-1.41.41.41.41.41.41.3-1.41.4-1.41.4-1.41.4-1.41.4-1.4-1.4-1.4-1.31.31.30.00.0
Intermittent access terminal intake (last 3 days)1.52.73.61.0-1.9-1.8-1.6-1.71.71.71.81.71.91.7-1.81.7-1.71.7-1.71.7-1.71.7-1.7-1.7-1.7-1.71.71.70.00.0
Intermittent access total infusions1.72.02.61.1-1.6-1.6-1.3-1.41.41.41.51.51.61.5-1.51.5-1.51.5-1.51.5-1.51.5-1.5-1.5-1.5-1.41.41.40.00.0
Intermittent access day 1 locomotion0.00.00.10.2-0.3-0.2-0.1-0.20.20.20.20.20.30.3-0.20.2-0.20.2-0.20.2-0.20.2-0.2-0.2-0.2-0.10.10.10.00.0
Intermittent access day 15 total locomotion0.00.10.30.3-0.4-0.5-0.1-0.40.30.30.50.40.50.4-0.40.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.30.30.30.00.0
Intermittent access total locomotion0.00.00.2-0.00.10.00.40.1-0.1-0.10.1-0.10.00.10.0-0.10.0-0.00.1-0.00.0-0.00.00.10.10.2-0.2-0.20.00.0
Intermittent access standard deviation0.42.02.60.6-1.6-1.6-1.1-1.61.61.61.61.41.51.5-1.51.4-1.51.5-1.41.5-1.51.5-1.5-1.5-1.5-1.31.31.30.00.0
Left kidney weight0.43.24.9-2.21.91.92.01.9-1.9-1.9-1.7-1.9-1.6-1.71.8-1.91.8-1.81.8-1.81.8-1.81.81.81.81.9-1.9-1.90.00.0
Right kidney weight0.53.24.7-1.52.02.02.21.9-2.0-1.9-1.7-1.9-1.7-1.81.9-1.91.9-1.81.9-1.91.9-1.81.81.91.91.9-1.9-1.90.00.0
Cocaine induced anxiety1.23.35.8-0.2-2.1-1.9-2.4-1.81.91.91.72.01.71.7-1.92.0-1.91.9-1.91.9-1.91.9-1.9-1.9-1.9-2.02.02.00.00.0
Post-drug Anxiety2.73.04.61.2-1.9-1.8-2.2-1.81.91.91.61.91.71.6-1.81.9-1.81.8-1.81.8-1.81.8-1.8-1.8-1.8-1.91.91.90.00.0
Baseline Anxiety0.30.48.93.00.40.31.00.2-0.1-0.1-0.1-0.50.0-0.20.3-0.40.3-0.30.4-0.30.3-0.30.30.30.30.4-0.4-0.40.00.0
Tail length0.42.23.01.1-1.7-1.7-1.3-1.51.51.51.71.51.71.6-1.61.5-1.61.6-1.51.6-1.61.6-1.6-1.6-1.6-1.51.51.50.00.0
Length with tail0.00.00.10.3-0.1-0.20.1-0.10.10.10.3-0.00.30.1-0.10.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.10.00.0
Length without tail0.31.82.4-0.41.51.51.51.4-1.4-1.4-1.3-1.5-1.3-1.51.5-1.41.4-1.41.4-1.41.4-1.41.41.41.41.4-1.4-1.40.00.0
Times rat made contact with spout1.31.52.0-0.4-1.3-1.3-1.3-1.31.31.31.21.41.31.3-1.31.3-1.31.3-1.31.3-1.31.3-1.3-1.3-1.3-1.21.21.20.00.0
Lifetime Intake1.31.72.30.9-1.5-1.5-1.1-1.31.31.31.41.41.51.4-1.41.3-1.41.4-1.31.4-1.41.4-1.4-1.4-1.4-1.31.31.30.00.0
Liver weight, left0.30.53.4-1.80.70.70.60.7-0.7-0.7-0.7-0.6-0.7-0.70.6-0.60.6-0.70.6-0.60.6-0.70.60.60.60.7-0.7-0.60.00.0
Liver weight, right1.93.24.1-0.72.02.01.92.0-2.0-2.0-1.8-1.9-1.9-1.91.9-1.91.9-1.91.9-1.91.9-1.91.91.91.91.9-1.9-1.90.00.0
Locomotor activity1.52.33.1-0.81.81.71.71.6-1.5-1.6-1.5-1.5-1.7-1.61.5-1.61.6-1.61.6-1.61.6-1.61.61.61.61.7-1.7-1.70.00.0
Locomotor testing distance0.30.61.10.30.90.91.00.8-0.8-0.8-0.7-0.8-0.9-0.70.8-0.90.8-0.80.8-0.80.8-0.80.80.80.80.9-0.9-0.90.00.0
Locomotor testing rearing0.10.31.4-1.20.60.50.70.5-0.5-0.5-0.4-0.5-0.4-0.40.4-0.50.5-0.50.5-0.50.5-0.50.50.50.50.6-0.6-0.60.00.0
Locomotion in novel chamber2.43.35.80.32.11.92.41.8-1.8-1.8-1.6-2.1-1.8-1.61.9-2.01.9-1.92.0-1.91.9-1.91.91.91.92.0-2.0-2.10.00.0
Locomotion in novel chamber post-restriction0.00.00.30.50.20.10.20.0-0.0-0.0-0.00.0-0.10.10.1-0.10.1-0.10.1-0.10.1-0.10.10.10.10.2-0.2-0.20.00.0
Fecal boli incidents, locomotor time 11.84.714.43.8-2.3-2.3-2.2-2.32.32.32.12.12.02.1-2.12.2-2.22.2-2.22.1-2.12.1-2.1-2.2-2.2-2.02.02.10.00.0
Change in fecal boli incidents, locomotor task0.40.49.0-3.00.20.3-0.10.3-0.3-0.3-0.4-0.1-0.2-0.40.2-0.20.3-0.30.2-0.30.3-0.30.30.30.2-0.00.0-0.10.00.0
Time >=10cm from walls, locomotor time 10.20.37.9-2.80.10.1-0.00.0-0.1-0.1-0.2-0.0-0.0-0.20.1-0.10.1-0.10.1-0.10.1-0.10.10.10.1-0.10.1-0.00.00.0
Bouts of movement, locomotor time 13.95.038.16.2-2.2-2.2-1.6-2.01.91.92.22.02.12.1-2.12.0-2.02.0-2.02.0-2.02.0-2.0-2.0-2.0-1.91.91.90.00.0
Total resting periods, locomotor time 13.84.431.55.6-2.1-2.1-1.6-1.91.81.82.01.91.92.0-2.01.9-1.91.9-1.91.9-1.91.9-1.9-1.9-1.9-1.91.91.90.00.0
Rest time, locomotor task time 13.45.416.44.1-2.4-2.5-2.0-2.42.32.32.52.22.42.4-2.32.3-2.32.4-2.32.3-2.32.3-2.3-2.3-2.3-2.32.32.20.00.0
Distance moved, locomotor task time 10.51.513.6-3.71.01.20.61.2-1.2-1.2-1.3-0.8-1.2-1.21.0-1.01.1-1.11.1-1.11.1-1.11.11.11.10.9-0.9-0.80.00.0
Vertical activity count, locomotor time 10.63.814.8-3.82.02.01.82.0-1.9-1.9-2.0-1.8-1.9-2.01.9-1.91.9-1.91.9-1.91.9-1.91.91.91.91.9-1.9-1.80.00.0
Time >=10cm from walls, locomotor time 20.10.20.40.6-0.6-0.6-0.4-0.50.40.40.50.60.50.4-0.60.5-0.50.5-0.50.5-0.50.5-0.5-0.5-0.5-0.60.60.60.00.0
Bouts of movement, locomotor time 20.82.515.13.9-1.6-1.6-1.6-1.41.41.41.51.51.41.5-1.51.5-1.51.5-1.51.5-1.51.5-1.5-1.5-1.5-1.61.61.50.00.0
Total resting periods, locomotor time 20.62.310.53.2-1.6-1.6-1.5-1.41.41.41.41.41.41.5-1.41.5-1.51.5-1.51.5-1.51.5-1.5-1.5-1.5-1.61.61.40.00.0
Rest time, locomotor task time 20.91.51.90.8-1.3-1.4-1.1-1.31.31.31.41.11.31.4-1.21.2-1.31.3-1.31.3-1.31.3-1.3-1.3-1.3-1.31.31.10.00.0
Distance moved, locomotor task time 20.60.86.2-2.50.80.80.70.9-0.9-0.9-0.8-0.7-0.7-0.90.8-0.80.8-0.80.8-0.80.8-0.80.80.80.80.8-0.8-0.70.00.0
Vertical activity count, locomotor time 20.81.811.8-3.41.21.31.31.3-1.3-1.3-1.2-1.2-1.0-1.31.2-1.21.2-1.21.3-1.21.2-1.21.21.21.21.3-1.3-1.20.00.0
Light reinforcement 10.00.00.40.6-0.2-0.2-0.1-0.00.00.00.10.20.10.2-0.20.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.1-0.20.20.20.00.0
Light reinforcement 20.41.03.31.8-1.0-1.1-0.7-1.01.01.01.10.91.01.1-1.00.9-1.01.0-0.91.0-1.01.0-1.0-1.0-1.0-1.01.01.00.00.0
Bone: marrow area0.71.62.21.1-1.5-1.4-1.4-1.41.41.41.31.41.31.4-1.41.3-1.31.3-1.31.3-1.31.3-1.3-1.3-1.3-1.31.31.30.00.0
Bone: maximum diameter0.30.74.32.1-0.8-0.8-0.7-0.80.80.80.80.60.80.8-0.70.8-0.80.8-0.80.8-0.80.8-0.8-0.8-0.8-0.70.70.70.00.0
Bone: maximum force0.10.20.4-0.60.40.50.40.5-0.5-0.5-0.5-0.4-0.5-0.50.5-0.40.5-0.50.5-0.50.5-0.50.50.50.50.4-0.4-0.40.00.0
Bone: maximum moment0.00.00.2-0.4-0.00.0-0.10.1-0.1-0.1-0.00.0-0.0-0.1-0.00.00.0-0.00.0-0.00.0-0.00.00.00.0-0.00.00.00.00.0
Mean time between licks in bursts0.21.01.4-0.0-1.1-1.1-1.1-1.11.11.11.01.21.11.1-1.11.1-1.11.1-1.11.1-1.11.1-1.1-1.1-1.1-1.01.01.00.00.0
Mean num. licks in bursts0.10.30.4-0.60.60.60.50.5-0.5-0.5-0.6-0.4-0.6-0.50.5-0.50.5-0.50.5-0.50.5-0.50.50.50.50.6-0.6-0.60.00.0
Cd content in liver3.03.34.2-0.62.12.01.91.9-1.9-1.9-1.9-2.0-2.0-1.91.9-1.91.9-1.91.9-1.91.9-1.91.91.91.91.9-1.9-1.90.00.0
Co content in liver0.40.50.6-0.60.70.70.70.7-0.7-0.7-0.7-0.8-0.8-0.70.8-0.70.7-0.70.7-0.70.7-0.70.70.70.70.7-0.7-0.70.00.0
Cu content in liver0.10.10.30.50.40.40.40.4-0.4-0.4-0.3-0.5-0.3-0.40.4-0.40.4-0.40.4-0.40.4-0.40.40.40.40.4-0.4-0.40.00.0
Fe content in liver0.10.11.1-1.1-0.2-0.2-0.2-0.20.20.20.20.40.30.2-0.30.2-0.20.2-0.20.2-0.20.2-0.2-0.2-0.2-0.20.20.20.00.0
K content in liver1.11.02.11.5-1.1-1.1-0.9-1.11.11.11.11.01.11.1-1.01.0-1.01.1-1.01.0-1.01.1-1.0-1.0-1.0-1.01.01.00.00.0
Mg content in liver1.01.12.01.4-1.1-1.2-1.0-1.11.11.11.10.91.01.1-1.01.1-1.11.1-1.01.1-1.11.1-1.1-1.1-1.1-1.01.01.00.00.0
Mn content in liver0.00.00.7-0.80.10.2-0.00.2-0.2-0.2-0.20.0-0.2-0.20.0-0.10.1-0.10.1-0.10.1-0.10.10.10.10.1-0.1-0.10.00.0
Na content in liver0.30.41.4-1.2-0.6-0.6-0.6-0.50.50.50.50.70.70.5-0.70.6-0.60.6-0.60.6-0.60.6-0.6-0.6-0.6-0.50.50.50.00.0
Rb content in liver1.01.11.50.5-1.2-1.2-1.2-1.11.11.11.11.21.01.1-1.21.1-1.11.1-1.11.1-1.11.1-1.1-1.1-1.1-1.11.11.10.00.0
Se content in liver0.30.40.6-0.80.70.70.70.7-0.7-0.7-0.7-0.7-0.6-0.70.7-0.70.6-0.60.7-0.60.6-0.60.60.60.60.7-0.7-0.70.00.0
Sr content in liver0.30.30.3-0.20.60.60.50.5-0.5-0.5-0.5-0.5-0.6-0.50.5-0.50.5-0.50.5-0.50.5-0.50.50.50.50.5-0.5-0.50.00.0
Zn content in liver0.50.61.00.50.90.81.00.8-0.8-0.8-0.7-1.0-0.8-0.80.9-0.80.8-0.80.8-0.80.8-0.80.80.80.80.8-0.8-0.80.00.0
Bone: minimum diameter1.12.12.71.6-1.7-1.6-1.5-1.51.51.51.51.41.51.5-1.41.5-1.51.5-1.51.5-1.51.5-1.5-1.5-1.5-1.51.51.50.00.0
Time in familiar zone, hab. session 10.00.00.0-0.20.20.20.10.2-0.2-0.2-0.2-0.1-0.2-0.20.2-0.20.2-0.20.2-0.20.2-0.20.20.20.20.1-0.1-0.20.00.0
Time in novel zone, hab. session 10.50.50.70.9-0.8-0.8-0.8-0.80.80.80.80.70.70.8-0.70.8-0.80.8-0.80.8-0.80.8-0.8-0.8-0.8-0.80.80.80.00.0
Total zone transitions, hab. session 12.83.95.0-1.82.22.22.12.0-1.9-1.9-2.0-2.1-2.0-2.02.1-2.12.0-2.02.0-2.02.0-2.02.02.02.02.1-2.1-2.10.00.0
Total locomotion distance, hab. session 13.04.36.1-2.52.32.32.22.1-2.1-2.1-2.1-2.1-2.1-2.12.1-2.12.1-2.12.1-2.12.1-2.12.12.12.12.2-2.2-2.20.00.0
Locomotion velocity, hab. session 11.82.54.0-2.01.81.71.71.6-1.6-1.6-1.6-1.6-1.6-1.61.6-1.61.6-1.61.6-1.61.6-1.61.61.61.61.7-1.7-1.70.00.0
Time in familiar zone, hab. session 21.51.73.81.9-1.4-1.4-1.4-1.31.41.41.21.21.21.3-1.21.3-1.31.3-1.31.3-1.31.3-1.3-1.3-1.3-1.41.41.40.00.0
Time in novel zone, hab. session 21.01.13.4-1.81.11.11.01.1-1.1-1.1-1.0-0.9-1.0-1.10.9-1.01.0-1.01.0-1.01.0-1.01.01.01.01.1-1.1-1.00.00.0
Total zone transitions, hab. session 20.20.20.4-0.10.60.50.60.5-0.5-0.5-0.5-0.6-0.5-0.50.6-0.50.5-0.50.5-0.50.5-0.50.50.50.50.5-0.5-0.50.00.0
Total locomotion distance, hab. session 20.40.61.2-1.10.80.80.80.8-0.8-0.8-0.7-0.7-0.7-0.70.7-0.70.7-0.70.8-0.70.7-0.70.70.70.70.8-0.8-0.80.00.0
Locomotion velocity, hab. session 20.30.40.8-0.90.60.70.60.6-0.6-0.6-0.6-0.6-0.6-0.60.6-0.60.6-0.60.6-0.60.6-0.60.60.60.60.6-0.6-0.70.00.0
Novel to familiar place preference ratio0.30.40.50.40.70.70.60.6-0.6-0.6-0.6-0.6-0.6-0.60.6-0.60.6-0.60.6-0.60.6-0.60.60.60.60.7-0.7-0.70.00.0
Novelty place preference0.50.70.9-0.20.90.90.80.9-0.9-0.9-0.9-0.8-0.9-0.90.8-0.90.9-0.90.9-0.90.9-0.90.90.90.90.9-0.9-0.90.00.0
Time in novel zone, NPP test0.50.60.8-0.10.80.90.80.9-0.9-0.9-0.8-0.7-0.8-0.80.8-0.80.8-0.80.8-0.80.8-0.80.80.80.80.8-0.8-0.80.00.0
Total zone transitions, NPP test0.91.42.1-1.51.31.31.31.1-1.1-1.1-1.1-1.3-1.1-1.11.3-1.21.2-1.21.2-1.21.2-1.21.21.21.21.2-1.2-1.20.00.0
Total locomotion distance, NPP test1.52.18.7-3.01.51.61.41.4-1.4-1.4-1.4-1.4-1.4-1.41.4-1.41.4-1.41.4-1.41.4-1.41.41.41.41.4-1.4-1.40.00.0
Locomotion velocity, NPP test1.41.98.5-2.91.41.51.31.3-1.4-1.4-1.4-1.3-1.3-1.31.3-1.31.3-1.31.3-1.31.3-1.31.31.31.31.4-1.4-1.30.00.0
Intraocular pressure0.10.10.20.30.40.40.30.3-0.3-0.3-0.3-0.4-0.4-0.40.4-0.30.3-0.30.3-0.30.3-0.30.30.30.30.3-0.3-0.30.00.0
Delta distance traveled before/after self-admin0.20.21.5-1.20.40.5-0.10.6-0.6-0.6-0.7-0.4-0.6-0.50.5-0.30.4-0.40.4-0.40.4-0.40.40.40.40.2-0.2-0.20.00.0
Delta ambulatory time before/after self-admin0.10.11.2-1.10.20.4-0.10.4-0.4-0.4-0.5-0.3-0.4-0.30.3-0.20.3-0.30.2-0.30.3-0.30.30.30.20.1-0.1-0.10.00.0
Parametrial fat weight0.51.11.3-1.01.11.11.21.1-1.1-1.1-1.1-1.0-1.1-1.11.1-1.11.1-1.11.1-1.11.1-1.11.11.11.11.0-1.0-1.10.00.0
Pavlov. Cond. lever latency2.73.44.3-1.62.12.11.71.9-2.0-2.0-2.1-1.9-2.1-2.02.0-1.91.9-2.01.9-1.91.9-1.91.91.91.91.8-1.8-1.80.00.0
Pavlov. Cond. magazine entry latency1.82.33.01.2-1.7-1.7-1.6-1.51.61.61.61.61.61.6-1.61.6-1.61.6-1.61.6-1.61.6-1.6-1.6-1.6-1.61.61.60.00.0
Pavlov. Cond. change in total contacts1.21.31.81.3-1.3-1.3-1.1-1.21.21.21.21.11.21.2-1.21.2-1.21.2-1.21.2-1.21.2-1.2-1.2-1.2-1.11.11.10.00.0
Pavlov. Cond. index score3.54.45.61.8-2.4-2.3-2.1-2.22.22.22.32.22.32.2-2.22.2-2.22.2-2.22.2-2.22.2-2.2-2.2-2.2-2.12.12.10.00.0
Pavlov. Cond. latency score3.54.55.62.0-2.4-2.4-2.1-2.22.22.22.32.22.32.2-2.22.2-2.22.2-2.22.2-2.22.2-2.2-2.2-2.2-2.12.12.10.00.0
Pavlov. Cond. lever contacts2.83.34.21.9-2.0-2.0-1.7-1.91.91.92.01.82.01.9-1.91.9-1.91.9-1.91.9-1.91.9-1.9-1.9-1.9-1.71.71.80.00.0
Pavlov. Cond. magazine entry number1.21.52.0-0.81.41.41.31.3-1.3-1.3-1.3-1.3-1.3-1.31.3-1.31.3-1.31.3-1.31.3-1.31.31.31.31.3-1.3-1.30.00.0
Pavlov. Cond. intertrial magazine entries2.53.04.7-2.21.91.91.71.8-1.8-1.8-1.8-1.6-1.8-1.81.7-1.71.8-1.81.8-1.81.8-1.81.81.81.81.8-1.8-1.80.00.0
Pavlov. Cond. lever-magazine prob. diff.3.44.25.31.9-2.3-2.3-2.0-2.12.12.12.22.12.22.1-2.22.1-2.12.1-2.12.1-2.12.1-2.1-2.1-2.1-2.12.12.10.00.0
Pavlov. Cond. response bias1.72.12.71.0-1.6-1.6-1.4-1.51.51.51.61.51.61.5-1.51.5-1.51.5-1.51.5-1.51.5-1.5-1.5-1.5-1.51.51.50.00.0
Pavlov. Cond. lever latency0.00.10.8-0.9-0.2-0.2-0.2-0.10.10.10.10.20.20.1-0.20.2-0.10.1-0.10.1-0.10.1-0.1-0.1-0.1-0.20.20.20.00.0
Pavlov. Cond. magazine entry latency0.10.10.2-0.40.30.40.30.3-0.3-0.3-0.4-0.3-0.4-0.30.3-0.30.3-0.30.3-0.30.3-0.30.30.30.30.3-0.3-0.30.00.0
Pavlov. Cond. change in total contacts0.30.81.0-0.71.01.01.00.9-0.9-0.9-0.9-1.0-1.0-0.90.9-0.90.9-0.90.9-0.90.9-0.90.90.90.90.9-0.9-1.00.00.0
Pavlov. Cond. index score0.00.10.50.70.20.20.20.2-0.2-0.2-0.2-0.3-0.3-0.20.2-0.20.2-0.20.2-0.20.2-0.20.20.20.20.2-0.2-0.20.00.0
Pavlov. Cond. latency score0.20.30.40.30.60.60.60.6-0.6-0.6-0.6-0.6-0.6-0.60.6-0.60.6-0.60.6-0.60.6-0.60.60.60.60.6-0.6-0.60.00.0
Pavlov. Cond. lever contacts0.00.11.71.3-0.0-0.1-0.0-0.10.10.10.1-0.00.00.1-0.00.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.1-0.00.00.00.00.0
Pavlov. Cond. magazine entry number0.10.20.3-0.3-0.5-0.5-0.4-0.40.40.40.40.40.50.4-0.40.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.40.40.40.00.0
Pavlov. Cond. intertrial magazine entries0.10.30.40.2-0.6-0.6-0.5-0.60.60.60.60.50.60.6-0.50.6-0.60.6-0.60.6-0.60.6-0.6-0.6-0.6-0.60.60.60.00.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.60.80.20.20.20.2-0.1-0.1-0.1-0.2-0.2-0.20.2-0.20.2-0.20.2-0.20.2-0.20.20.20.20.1-0.1-0.20.00.0
Pavlov. Cond. response bias0.00.00.70.8-0.1-0.1-0.1-0.10.20.20.10.10.10.1-0.10.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.10.00.0
Time in closed arm before self-admin0.00.00.6-0.8-0.00.00.20.3-0.4-0.30.00.10.10.0-0.1-0.00.0-0.00.1-0.00.0-0.00.00.00.00.0-0.0-0.00.00.0
Time in closed arm after self-admin0.30.40.60.1-0.7-0.7-0.5-0.60.60.60.70.80.70.7-0.70.6-0.70.7-0.60.7-0.70.7-0.7-0.7-0.7-0.60.60.60.00.0
Time in open arm before self-admin2.02.43.7-0.21.81.71.91.6-1.6-1.6-1.4-1.8-1.6-1.51.6-1.71.6-1.61.7-1.61.6-1.61.61.61.61.7-1.7-1.70.00.0
Time in open arm after self-admin0.50.51.81.30.80.70.80.8-0.8-0.8-0.6-1.0-0.7-0.70.8-0.70.7-0.70.7-0.70.7-0.70.70.70.70.7-0.7-0.70.00.0
Bone: periosteal estimation0.61.42.21.5-1.3-1.3-1.2-1.21.21.21.21.21.21.2-1.21.2-1.21.2-1.21.2-1.21.2-1.2-1.2-1.2-1.21.21.20.00.0
Bone: periosteal perimeter0.71.34.32.1-1.2-1.2-1.1-1.21.21.21.21.01.11.2-1.11.1-1.21.2-1.11.1-1.11.2-1.1-1.2-1.1-1.11.11.20.00.0
Bone: post-yield work1.22.14.32.1-1.5-1.5-1.5-1.51.51.51.41.41.41.5-1.41.5-1.51.5-1.51.5-1.51.5-1.5-1.5-1.5-1.51.51.50.00.0
Progressive ratio test 1 active lever presses0.50.91.41.2-1.1-1.1-0.6-1.11.01.01.10.91.21.1-1.00.9-1.01.0-1.01.0-1.01.0-1.0-1.0-1.0-0.90.90.90.00.0
Progressive ratio test 1 breakpoint0.61.11.81.3-1.2-1.2-0.6-1.21.11.11.21.01.31.2-1.11.0-1.11.1-1.01.1-1.11.1-1.1-1.1-1.1-0.90.90.90.00.0
Progressive ratio test 1 inactive lever presses0.00.10.40.60.30.20.6-0.10.00.0-0.0-0.4-0.1-0.10.3-0.30.2-0.20.3-0.20.2-0.20.20.20.20.4-0.4-0.40.00.0
Progressive ratio test 2 active lever presses0.20.30.6-0.7-0.6-0.6-0.2-0.60.60.50.60.50.80.6-0.50.5-0.50.5-0.50.5-0.50.5-0.5-0.5-0.5-0.40.40.40.00.0
Progressive ratio test 2 breakpoint0.20.20.5-0.7-0.5-0.5-0.1-0.50.50.40.50.40.70.5-0.50.4-0.50.5-0.40.5-0.50.5-0.5-0.4-0.4-0.30.30.30.00.0
Progressive ratio test 2 inactive lever presses0.20.61.11.1-0.9-0.9-0.5-1.11.01.00.90.80.90.8-0.80.8-0.80.8-0.80.8-0.80.8-0.8-0.8-0.8-0.70.70.70.00.0
Incentive Sensitization - Responses0.00.10.50.70.20.10.70.2-0.2-0.30.1-0.20.10.00.1-0.20.1-0.10.2-0.10.1-0.10.10.10.20.3-0.3-0.30.00.0
Incentive Sensitization - Breakpoint0.00.00.40.7-0.0-0.10.40.0-0.0-0.10.3-0.00.20.2-0.1-0.0-0.10.1-0.00.1-0.10.1-0.1-0.1-0.00.1-0.1-0.10.00.0
Sum of active levers in priming session hrs 5-60.20.11.5-1.20.40.40.20.2-0.2-0.2-0.3-0.2-0.4-0.50.3-0.30.3-0.30.3-0.30.3-0.30.30.30.30.3-0.3-0.30.00.0
Progressive ratio0.10.23.5-1.9-0.10.1-0.70.2-0.2-0.2-0.30.3-0.1-0.3-0.10.2-0.00.0-0.10.0-0.00.0-0.0-0.0-0.1-0.30.30.20.00.0
Food seeking constrained by brief footshock0.50.610.73.3-0.5-0.6-0.4-0.50.50.50.60.30.40.5-0.40.5-0.50.5-0.50.5-0.50.5-0.5-0.5-0.5-0.40.40.60.00.0
Seeking ratio, punishment vs. effort0.10.36.32.5-0.2-0.40.1-0.40.40.40.50.00.20.5-0.20.2-0.30.3-0.20.3-0.30.3-0.3-0.3-0.3-0.10.10.20.00.0
Retroperitoneal fat weight1.77.416.1-4.02.92.92.73.0-3.0-3.0-2.8-2.7-2.7-2.92.7-2.72.8-2.82.8-2.72.7-2.72.72.82.72.5-2.5-2.60.00.0
Reaction time number correct0.00.20.50.1-0.4-0.5-0.1-0.50.50.50.50.30.50.7-0.30.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.30.30.40.00.0
Reaction time mean minus median0.10.30.5-0.1-0.7-0.6-0.7-0.50.50.50.60.70.70.6-0.70.6-0.60.6-0.60.6-0.60.6-0.6-0.6-0.6-0.60.60.60.00.0
Reaction time mean minus median AUC0.10.40.7-0.3-0.7-0.7-0.8-0.60.60.60.60.80.70.6-0.70.7-0.60.6-0.70.6-0.60.6-0.6-0.6-0.7-0.70.70.70.00.0
Reaction time num false alarms0.61.11.50.1-1.2-1.2-1.1-1.11.11.11.11.21.01.0-1.21.1-1.11.1-1.11.1-1.11.1-1.1-1.1-1.1-1.11.11.10.00.0
Reaction time num false alarms AUC0.51.21.70.3-1.3-1.3-1.1-1.21.21.21.21.21.01.1-1.21.2-1.11.1-1.11.1-1.11.1-1.1-1.1-1.1-1.11.11.10.00.0
Reaction time trials correct on left0.00.20.50.1-0.4-0.5-0.1-0.50.50.50.50.30.50.7-0.30.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.30.30.40.00.0
Reaction time trials on left0.10.20.50.1-0.4-0.5-0.1-0.50.60.60.50.30.50.7-0.40.4-0.50.5-0.40.5-0.50.5-0.5-0.5-0.4-0.40.40.40.00.0
Reaction time mean0.00.00.10.1-0.2-0.2-0.2-0.10.10.10.20.20.20.2-0.20.2-0.20.2-0.20.2-0.20.2-0.2-0.2-0.2-0.20.20.20.00.0
Reaction time mean AUC0.10.10.20.2-0.4-0.4-0.4-0.30.30.30.40.40.40.4-0.40.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.40.40.40.00.0
Median of all reaction times0.10.20.60.8-0.5-0.5-0.4-0.40.40.40.40.40.40.5-0.40.4-0.40.4-0.40.4-0.40.4-0.4-0.4-0.4-0.40.40.40.00.0
Reaction time omissions0.71.21.70.5-1.2-1.1-1.3-1.21.21.21.01.21.01.2-1.11.2-1.11.1-1.21.1-1.11.1-1.1-1.1-1.1-1.11.11.10.00.0
Reaction time false alarm rate0.20.30.6-0.0-0.7-0.7-0.8-0.50.50.60.60.70.40.4-0.70.6-0.60.6-0.60.6-0.60.6-0.6-0.5-0.6-0.60.60.60.00.0
Reaction time premature initiation rate4.06.215.2-3.92.72.72.32.6-2.6-2.6-2.6-2.4-2.6-2.62.5-2.52.5-2.52.5-2.52.5-2.52.52.52.52.4-2.4-2.40.00.0
Reaction time premature initiations1.03.010.0-3.21.81.81.71.8-1.7-1.7-1.7-1.7-1.7-1.61.7-1.71.7-1.71.7-1.71.7-1.71.71.71.71.7-1.7-1.70.00.0
Std. dev. reaction times0.00.11.7-1.30.20.30.10.3-0.3-0.3-0.3-0.1-0.1-0.20.2-0.20.2-0.20.2-0.20.2-0.20.20.20.20.2-0.2-0.20.00.0
Reaction time trials completed0.10.20.50.1-0.4-0.5-0.1-0.50.60.60.50.30.50.7-0.40.4-0.50.5-0.40.5-0.50.5-0.5-0.5-0.4-0.40.40.40.00.0
Reaction time trials AUC0.10.30.70.0-0.5-0.6-0.3-0.70.70.70.60.40.60.8-0.50.5-0.60.6-0.50.6-0.60.6-0.6-0.6-0.5-0.50.50.50.00.0
Run reversals in cocaine runway, females0.00.10.20.40.20.30.00.2-0.3-0.3-0.3-0.2-0.2-0.40.2-0.20.2-0.20.2-0.20.2-0.20.20.20.20.2-0.2-0.20.00.0
Run reversals in cocaine runway, males0.60.712.03.50.50.21.20.6-0.5-0.6-0.1-0.6-0.3-0.30.4-0.60.4-0.40.5-0.40.4-0.40.40.40.40.6-0.6-0.60.00.0
Latency to leave start box in cocaine runway2.73.85.00.9-2.2-2.2-1.8-2.02.02.02.22.12.22.1-2.22.0-2.02.0-2.02.0-2.02.0-2.0-2.0-2.0-1.91.91.90.00.0
Latency to leave start box in cocaine runway, F3.34.15.82.4-2.2-2.2-2.0-2.12.02.12.12.32.12.0-2.22.1-2.12.1-2.12.1-2.12.1-2.1-2.1-2.1-2.02.02.00.00.0
Latency to leave start box in cocaine runway, M0.60.63.6-1.9-0.7-0.8-0.4-0.60.70.70.90.71.00.9-0.80.7-0.70.7-0.70.7-0.70.7-0.7-0.7-0.7-0.60.60.60.00.0
Std. dev. time between licks in bursts0.30.51.6-1.30.80.80.60.6-0.6-0.6-0.8-0.7-0.8-0.60.7-0.70.7-0.70.7-0.70.7-0.70.70.70.70.8-0.8-0.80.00.0
Total sessions with >9 infusions0.60.71.10.5-1.0-1.0-0.7-0.90.80.91.00.91.11.0-0.90.9-0.90.9-0.90.9-0.90.9-0.9-0.9-0.9-0.80.80.80.00.0
Short access day 1 total inactive lever presses0.20.40.80.3-0.7-0.8-0.2-0.70.60.60.90.50.80.9-0.70.6-0.70.7-0.60.7-0.70.7-0.7-0.7-0.7-0.50.50.50.00.0
Short access day 10 total inactive lever presses0.00.10.7-0.8-0.1-0.1-0.2-0.40.40.40.10.10.00.1-0.10.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.10.00.0
Short access day 1 total infusions0.10.30.4-0.1-0.6-0.6-0.5-0.60.50.50.60.60.70.6-0.60.6-0.60.6-0.60.6-0.60.6-0.6-0.6-0.6-0.50.50.50.00.0
Short access day 10 total infusions0.91.55.22.3-1.3-1.4-0.6-1.21.11.11.51.11.41.5-1.31.1-1.31.3-1.21.3-1.31.3-1.3-1.3-1.2-1.01.01.00.00.0
Short access total infusions0.60.81.20.4-1.1-1.0-0.8-0.90.80.91.00.91.11.0-1.00.9-1.01.0-0.91.0-1.01.0-1.0-1.0-1.0-0.90.90.90.00.0
Short access day 1 locomotion0.10.20.60.20.50.40.80.4-0.5-0.4-0.2-0.5-0.3-0.30.4-0.50.4-0.40.4-0.40.4-0.40.40.40.40.5-0.5-0.50.00.0
Short access day 10 total locomotion0.10.50.7-0.5-0.8-0.8-0.7-0.70.70.70.80.80.80.8-0.80.8-0.80.8-0.80.8-0.80.8-0.8-0.8-0.8-0.70.70.70.00.0
Short access total locomotion0.20.32.4-1.60.50.50.70.5-0.6-0.6-0.5-0.5-0.3-0.50.5-0.50.5-0.50.5-0.50.5-0.50.50.50.50.6-0.6-0.60.00.0
One hour access (0.3 mA shock)0.20.20.6-0.50.50.50.80.5-0.5-0.5-0.4-0.5-0.4-0.40.5-0.50.5-0.50.5-0.50.5-0.50.50.50.50.6-0.6-0.60.00.0
Compulsive drug intake1.72.53.2-1.01.81.81.51.6-1.6-1.6-1.7-1.6-1.8-1.71.6-1.61.7-1.71.6-1.71.7-1.71.71.71.71.6-1.6-1.60.00.0
One hour access (shock baseline)0.20.50.80.0-0.8-0.8-0.5-0.70.60.60.80.70.90.8-0.80.7-0.80.8-0.70.8-0.80.8-0.8-0.8-0.8-0.60.60.60.00.0
Social response proportion3.54.412.9-3.62.32.31.82.0-2.0-2.0-2.3-2.1-2.1-2.22.2-2.12.1-2.12.1-2.12.1-2.12.12.12.12.1-2.1-2.00.00.0
Social responses5.67.319.7-4.42.93.02.22.6-2.7-2.7-3.0-2.7-2.8-2.92.8-2.62.7-2.82.7-2.72.7-2.72.72.72.72.5-2.5-2.50.00.0
Social time1.92.910.2-3.21.81.91.31.7-1.7-1.7-1.8-1.6-1.8-1.81.7-1.61.7-1.71.7-1.71.7-1.71.71.71.71.6-1.6-1.60.00.0
Soleus weight0.72.22.7-1.61.61.61.41.6-1.6-1.6-1.6-1.4-1.6-1.61.5-1.51.5-1.51.5-1.51.5-1.51.51.51.51.5-1.5-1.50.00.0
Bone: stiffness0.00.00.20.4-0.2-0.2-0.2-0.10.10.10.20.10.20.1-0.10.2-0.20.2-0.20.2-0.20.2-0.2-0.2-0.2-0.30.30.30.00.0
Tibialis anterior weight2.910.013.3-3.63.53.53.23.3-3.3-3.3-3.2-3.1-3.2-3.33.2-3.33.3-3.33.3-3.33.3-3.33.33.33.33.3-3.3-3.30.00.0
Time to tail flick, vehicle, before self-admin0.10.10.20.20.40.30.20.2-0.2-0.2-0.4-0.5-0.5-0.30.5-0.30.3-0.30.3-0.30.3-0.30.30.30.30.3-0.3-0.30.00.0
Time to tail flick, vehicle, after self-admin0.30.61.81.4-0.7-0.7-0.9-1.01.11.10.50.60.50.8-0.60.8-0.80.7-0.80.7-0.70.7-0.7-0.8-0.7-0.70.70.70.00.0
Time to tail flick, test, before self-admin0.10.20.70.8-0.4-0.50.1-0.20.30.20.60.50.60.2-0.60.3-0.40.4-0.30.4-0.40.4-0.4-0.3-0.4-0.30.30.30.00.0
Time to tail flick, test, after self-admin0.20.24.22.0-0.0-0.10.50.1-0.1-0.10.3-0.10.20.0-0.0-0.1-0.00.00.00.0-0.00.0-0.0-0.0-0.00.1-0.1-0.10.00.0
Delta time to tail flick, vehicle, before/after SA0.00.00.30.6-0.1-0.10.1-0.30.30.30.20.30.10.2-0.20.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.1-0.00.00.00.00.0
Delta time to tail flick, test, before/after SA0.50.71.20.80.90.90.90.7-0.7-0.7-0.8-1.1-0.9-0.61.0-0.80.8-0.80.8-0.80.8-0.80.80.80.80.8-0.8-0.80.00.0
Tibia length0.72.02.5-1.21.61.61.41.5-1.5-1.5-1.4-1.6-1.5-1.51.5-1.41.5-1.51.4-1.51.5-1.51.51.51.51.5-1.5-1.40.00.0
Ambulatory time before self-admin0.00.10.10.4-0.3-0.3-0.1-0.30.30.30.30.30.30.3-0.30.2-0.30.3-0.30.3-0.30.3-0.3-0.3-0.3-0.20.20.20.00.0
Ambulatory time after self-admin0.30.40.6-0.60.70.70.50.8-0.8-0.8-0.8-0.7-0.7-0.60.7-0.60.6-0.60.6-0.60.6-0.60.60.60.60.6-0.6-0.60.00.0
Bone: tissue strength0.00.00.6-0.80.10.10.00.1-0.1-0.1-0.1-0.2-0.1-0.10.1-0.00.1-0.10.1-0.10.1-0.10.10.10.1-0.00.0-0.00.00.0
Total heroin consumption1.31.62.91.7-1.4-1.4-1.6-1.21.21.21.31.11.11.1-1.21.3-1.31.3-1.31.3-1.31.3-1.3-1.3-1.3-1.41.41.40.00.0
Bone: trabecular number1.01.92.8-0.71.61.51.71.4-1.4-1.4-1.3-1.5-1.3-1.41.4-1.51.4-1.41.5-1.41.4-1.41.41.41.41.6-1.6-1.50.00.0
Bone: trabecular spacing1.21.72.20.5-1.5-1.5-1.5-1.41.41.41.31.51.31.4-1.41.4-1.41.4-1.41.4-1.41.4-1.4-1.4-1.4-1.41.41.40.00.0
Bone: trabecular thickness0.60.91.1-0.81.01.11.01.0-1.0-1.0-0.9-1.0-1.0-1.01.0-1.01.0-1.01.0-1.01.0-1.01.01.01.01.0-1.0-1.00.00.0
Bone: trabecular tissue density0.81.41.90.3-1.3-1.3-1.4-1.31.31.31.11.31.21.3-1.21.3-1.31.2-1.31.3-1.21.2-1.2-1.3-1.2-1.21.21.30.00.0
Water consumed over 24 hours0.10.23.7-1.90.30.30.20.3-0.3-0.3-0.3-0.1-0.2-0.30.2-0.30.3-0.30.3-0.30.3-0.30.30.30.30.3-0.3-0.30.00.0
Number of responses in last shaping day0.70.93.31.8-1.0-1.0-0.8-0.90.90.90.90.90.90.9-0.90.9-0.90.9-0.90.9-0.90.9-0.9-0.9-0.9-0.90.90.90.00.0