Hub : Genes

Tank

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Tank 0.04 0.03 3.7e-03 0.03 0.03 0.02 0.03 3.1e-04 6.3e-04 1.6e-03 6.5e-04
2 pVTA intron excision ratio chr3_66573535_66574956 0.04 0.03 7.8e-03 0 0.01 0.01 0.01 1.3e-01 4.1e-02 7.7e-02 8.8e-02
3 Adipose intron excision ratio chr3_66522992_66558144 0.11 0.06 3.7e-07 0.06 0.04 0.04 0.05 8.0e-07 4.4e-05 1.2e-05 1.9e-06
4 Adipose alternative TSS XM_006234273.5 0.04 0.03 2.6e-03 0.02 0 0 0.01 3.6e-03 1.7e-01 1.9e-01 3.6e-02
5 Adipose gene expression Tank 0.21 0.08 0.0e+00 0.1 0.13 0.12 0.12 4.2e-11 5.5e-14 9.5e-14 1.1e-13
6 NAcc alternative polyA XM_006234273.5 0.05 0.03 2.1e-03 0.01 0.01 0.01 0.02 1.7e-03 1.8e-02 2.2e-03 4.5e-04
7 BLA gene expression Tank 0.16 0.09 1.6e-04 0.06 0.05 0.02 0.06 6.9e-04 1.5e-03 2.3e-02 7.0e-04
8 IC gene expression Tank 0.15 0.11 1.7e-03 0.06 0.04 0.05 0.04 2.2e-03 5.7e-03 3.9e-03 1.2e-02
9 NAcc alternative polyA XM_039104358.2 0.12 0.06 1.4e-08 0.06 0.06 0.06 0.06 2.1e-09 9.8e-09 3.4e-09 5.6e-09
10 NAcc isoform ratio XM_039104358.2 0.1 0.05 5.1e-09 0.05 0.05 0.06 0.06 7.4e-08 2.3e-08 2.8e-09 4.1e-09
11 NAcc intron excision ratio chr3_66571619_66573417 0.04 0.03 1.7e-04 0.03 0.03 0.02 0.03 4.8e-05 6.2e-05 1.1e-04 3.8e-05
12 Adipose alternative TSS XM_006234273.5 0.04 0.03 2.9e-03 0.02 0 0.01 0.01 2.8e-03 1.1e-01 3.4e-02 1.3e-02
13 Adipose isoform ratio XM_006234274.4 0.08 0.05 5.7e-05 0.03 0.01 0.01 0.02 2.9e-04 8.4e-03 2.7e-02 2.5e-03
14 Adipose intron excision ratio chr3_66589142_66598022 0.05 0.03 1.4e-03 0.02 0.01 0.01 0.01 1.6e-03 7.4e-03 1.5e-02 1.4e-02
15 NAcc intron excision ratio chr3_66573535_66574956 0.05 0.03 1.7e-04 0.02 0.02 0.02 0.03 2.1e-04 1.0e-03 1.4e-04 5.2e-05
16 Liver intron excision ratio chr3_66573535_66588383 0.05 0.03 2.9e-04 0 0.02 0.01 0.01 8.0e-02 2.6e-03 1.2e-02 2.5e-02
17 Liver gene expression Tank 0.32 0.11 0.0e+00 0.15 0.15 0.16 0.16 8.8e-17 8.7e-17 4.2e-17 7.7e-17
18 IL mRNA stability Tank 0.3 0.16 7.5e-03 0.03 0.06 0.01 0.04 5.5e-02 1.4e-02 1.4e-01 3.4e-02
19 pVTA isoform ratio XM_039104358.2 0.1 0.06 1.1e-04 0.05 0.04 0.04 0.05 4.5e-05 5.4e-04 2.8e-04 1.2e-04
20 BLA alternative TSS XM_039104353.2 0.14 0.09 3.3e-03 -0 0.03 0 0 8.1e-01 1.5e-02 2.7e-01 2.6e-01
21 BLA alternative TSS XM_039104353.2 0.11 0.07 8.2e-03 -0 0.02 0.01 -0 7.3e-01 3.4e-02 9.6e-02 5.7e-01
22 NAcc mRNA stability Tank 0.04 0.03 5.4e-03 0.01 0 0 0 4.9e-03 5.7e-02 2.0e-01 5.3e-02
23 NAcc gene expression Tank 0.11 0.06 1.3e-08 0.06 0.06 0.06 0.06 9.0e-09 7.2e-10 4.1e-10 9.1e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density1.11.95.5-0.52.30.70.51.2-0.7-0.6-0.70.60.90.60.6-0.6-2.11.02.3-0.80.72.02.32.3-1.91.5
Area under the delay curve0.30.40.90.6-0.8-0.8-0.6-0.50.20.90.8-0.3-0.5-0.6-0.70.7-0.5-0.3-0.80.1-0.1-0.4-0.8-0.80.9-0.1
BMI with tail0.10.31.1-0.20.10.40.40.4-0.4-0.3-0.40.30.50.40.4-0.4-1.00.50.30.7-0.60.8-0.9-0.9-1.01.0
BMI without tail0.61.73.5-0.90.51.31.11.1-1.1-1.3-1.31.11.31.21.4-1.4-0.51.20.8-0.4-1.61.7-1.9-1.9-1.81.7
Body weight0.20.71.8-1.00.31.00.80.6-0.8-0.9-0.80.80.80.80.9-0.91.00.60.10.2-1.20.0-1.3-1.2-0.2-0.4
Weight adjusted by age1.42.16.10.3-0.7-1.4-1.2-1.31.31.61.6-1.2-1.5-1.3-1.51.51.5-1.5-1.20.91.3-2.11.21.32.2-2.5
Bone surface1.52.77.5-1.32.71.51.41.9-1.5-1.5-1.51.41.61.41.4-1.4-1.01.62.6-1.7-0.21.81.81.8-1.91.0
Bone volume1.42.56.9-1.12.61.31.11.7-1.2-1.2-1.31.11.31.21.1-1.1-1.81.52.6-1.40.12.11.91.9-2.21.5
Breakpoint value in progressive ratio session7.48.912.83.0-2.9-3.4-3.4-3.23.63.33.3-3.3-3.4-3.4-3.53.5-2.9-3.5-2.73.43.2-1.91.51.41.9-0.7
Number of licking bursts0.10.11.50.50.1-0.2-0.2-0.20.20.10.0-0.2-0.1-0.2-0.10.11.2-0.2-0.1-0.10.3-0.40.40.40.3-0.5
Context. condit. distance diff. score0.10.10.6-0.1-0.2-0.1-0.2-0.30.20.10.2-0.2-0.2-0.2-0.20.20.6-0.3-0.4-0.20.2-0.70.10.20.8-0.8
Locomotion velocity, session 10.10.10.5-0.2-0.20.30.20.1-0.2-0.2-0.20.20.20.30.2-0.20.70.1-0.2-0.5-0.3-0.1-0.5-0.50.1-0.1
Locomotion distance, session 10.10.22.1-0.30.20.20.00.1-0.1-0.00.10.20.00.1-0.00.01.4-0.00.0-0.4-0.1-0.40.20.20.6-0.8
Locomotion velocity, session 20.80.91.61.2-1.0-1.1-1.1-1.01.11.31.2-1.1-1.1-1.1-1.21.2-0.2-1.0-0.91.20.9-0.50.40.40.5-0.0
Locomotion distance, session 20.30.42.8-0.80.90.70.40.6-0.6-0.5-0.30.60.50.50.3-0.31.70.40.5-0.6-0.3-0.20.50.50.3-0.7
Locomotion velocity, session 30.40.41.80.50.2-0.5-0.6-0.30.40.60.8-0.4-0.5-0.6-0.70.7-0.3-0.40.1-0.70.9-0.11.41.30.5-0.1
Locomotion distance, session 30.80.93.3-1.01.50.90.81.0-0.9-0.9-0.70.90.90.80.7-0.70.50.91.3-1.8-0.20.61.11.1-0.30.0
Stereotopy head waving bouts, day 30.50.62.1-0.61.10.80.80.9-0.8-0.8-0.70.80.80.80.7-0.70.40.81.1-1.4-0.30.60.50.5-0.60.2
Stereotopy head waving duration, day 30.10.10.3-0.20.50.20.30.3-0.3-0.2-0.30.30.20.30.2-0.20.50.20.4-0.5-0.10.00.30.30.0-0.3
Locomotion velocity, session 70.00.00.2-0.1-0.10.10.00.0-0.0-0.1-0.00.00.0-0.00.0-0.0-0.40.0-0.10.3-0.1-0.0-0.1-0.1-0.00.0
Locomotion distance, session 70.20.21.5-0.3-0.1-0.2-0.0-0.20.10.10.1-0.1-0.3-0.1-0.10.10.9-0.3-0.40.50.2-1.00.30.30.8-1.2
Stereotopy head waving bouts, day 70.10.10.30.30.00.2-0.2-0.00.10.00.3-0.10.1-0.0-0.30.3-0.3-0.10.1-0.50.20.30.20.1-0.20.4
Stereotopy head waving duration, day 70.10.21.50.4-0.00.0-0.20.00.10.10.2-0.10.1-0.1-0.20.2-1.20.00.2-0.30.10.70.0-0.0-0.60.9
Locomotion velocity, session 80.10.10.20.2-0.1-0.2-0.4-0.20.20.40.5-0.2-0.3-0.3-0.50.50.2-0.2-0.2-0.00.2-0.10.10.10.3-0.1
Locomotion distance, session 80.40.52.9-0.2-0.2-0.2-0.4-0.40.20.30.5-0.2-0.4-0.4-0.50.51.5-0.5-0.6-0.10.4-1.30.40.51.5-1.7
Degree of sensitization distance1.61.65.11.2-1.6-1.3-1.2-1.51.41.31.1-1.3-1.4-1.3-1.21.2-0.0-1.5-1.72.30.8-1.5-0.2-0.21.1-1.1
Degree of sensitization stereotypy0.30.30.70.8-0.7-0.4-0.7-0.60.60.60.9-0.7-0.5-0.6-0.80.8-0.8-0.6-0.50.20.50.00.0-0.00.10.4
Conditioned locomotion0.60.72.00.5-0.4-0.8-1.0-0.80.70.80.8-0.7-0.8-0.8-0.80.80.6-0.9-0.70.80.8-1.00.60.71.3-1.4
Cocaine response after cond. corrected4.85.810.02.0-2.5-2.6-2.8-2.82.92.52.5-2.9-2.7-2.8-2.62.6-1.5-2.8-2.53.22.6-1.91.21.11.8-1.0
Cocaine response after cond. not corrected3.94.69.21.4-2.3-2.1-2.4-2.52.42.12.2-2.5-2.4-2.5-2.32.3-0.7-2.5-2.43.02.1-2.10.90.92.0-1.5
Cocaine response before conditioning0.60.82.1-1.40.41.00.80.8-1.1-1.0-0.81.00.90.90.7-0.71.40.80.2-0.5-1.2-0.3-1.0-1.00.3-0.6
Saline control response0.20.31.70.5-0.5-0.1-0.4-0.40.10.20.4-0.2-0.3-0.5-0.30.30.9-0.3-0.7-0.40.0-1.0-0.3-0.21.3-1.3
Bone: connectivity density0.81.35.2-0.72.10.70.51.0-0.5-0.7-0.60.50.70.60.6-0.6-1.20.71.9-0.90.71.12.32.3-1.20.6
Bone: cortical apparent density0.30.41.6-0.60.70.30.40.7-0.6-0.2-0.00.60.60.40.1-0.1-1.30.80.9-0.8-0.31.20.20.1-0.71.1
Bone: cortical area2.03.14.7-2.12.02.12.02.0-2.0-2.1-2.22.01.92.02.0-2.01.31.91.8-2.0-1.60.9-0.3-0.2-1.0-0.1
Bone: cortical porosity1.21.32.8-1.50.81.01.01.1-1.0-1.1-1.11.11.11.01.0-1.0-0.81.21.1-0.3-1.11.5-0.8-0.9-1.51.7
Bone: cortical porosity2.83.04.5-2.11.71.81.82.0-1.8-1.9-1.91.81.91.71.8-1.8-0.01.91.9-1.2-1.72.0-0.8-0.8-2.01.8
Bone: cortical thickness2.23.75.2-2.12.02.22.02.2-2.2-2.2-2.12.12.22.02.0-2.00.62.32.0-1.9-2.01.8-1.0-0.9-1.71.1
Bone: cortical thickness5.76.710.0-3.23.02.92.93.0-2.9-2.8-2.82.93.02.82.7-2.71.03.03.0-2.6-2.32.4-0.6-0.5-2.31.4
Bone: cortical tissue density0.30.52.1-0.50.80.30.30.7-0.6-0.20.00.50.60.40.0-0.0-1.50.80.9-0.8-0.21.30.30.3-0.81.3
Condit. Reinf. active minus inactive responses3.84.26.7-2.32.62.32.42.4-2.3-2.2-2.32.32.32.32.3-2.31.22.32.5-2.0-1.61.80.00.1-1.90.9
Condit. Reinf. active-inactive response ratio1.21.32.2-1.31.51.21.31.3-1.3-1.3-1.31.31.31.31.3-1.30.71.31.3-1.1-0.80.70.10.2-0.80.1
Condit. Reinf. active responses3.94.86.3-2.42.32.52.52.5-2.4-2.4-2.52.42.52.52.4-2.41.02.52.4-1.9-2.12.1-0.9-0.8-2.31.4
Condit. Reinf. inactive responses3.23.97.5-1.61.52.02.02.1-1.9-1.9-2.02.02.12.01.9-1.9-0.22.12.0-1.5-2.12.7-1.4-1.5-2.72.6
Incentive salience index mean3.54.36.9-2.42.62.42.42.4-2.3-2.3-2.32.32.32.42.3-2.31.62.22.5-2.2-1.51.50.30.3-1.70.6
Condit. Reinf. lever presses0.40.51.4-1.00.70.90.90.8-0.7-0.8-0.80.70.70.90.8-0.81.20.60.6-0.8-0.60.10.00.0-0.3-0.2
Condit. Reinf. active minus inactive responses2.43.113.7-2.61.32.01.81.4-1.7-2.0-1.81.71.51.71.8-1.83.71.30.7-1.4-1.7-1.0-0.8-0.60.9-2.2
Condit. Reinf. active-inactive response ratio1.72.06.0-2.11.01.61.61.2-1.4-1.6-1.61.41.31.51.6-1.62.41.20.6-1.0-1.5-0.5-0.9-0.70.6-1.4
Condit. Reinf. active responses1.92.714.3-2.51.31.81.61.3-1.6-1.7-1.51.61.41.41.5-1.53.81.20.6-1.1-1.5-1.0-0.6-0.41.1-2.2
Condit. Reinf. inactive responses0.10.21.5-0.20.00.0-0.1-0.10.10.00.2-0.0-0.1-0.2-0.20.21.2-0.2-0.20.30.1-0.70.30.30.7-0.9
Condit. Reinf. lever presses1.11.59.1-1.71.11.10.90.9-1.1-1.1-0.91.10.90.91.0-1.03.00.80.5-1.1-0.8-1.00.20.31.2-2.1
Condit. Reinf. lever reinforcers received1.42.013.7-2.10.91.31.10.8-1.2-1.3-1.11.10.91.01.1-1.13.70.80.2-0.8-1.1-1.4-0.3-0.11.5-2.5
Conditioned reinforcement - actives0.71.13.6-0.71.31.21.11.3-1.1-1.3-1.31.21.21.00.9-0.90.41.11.3-1.9-0.71.10.30.3-0.80.6
Conditioned reinforcement - inactives0.50.74.6-0.8-0.80.40.20.2-0.4-0.5-0.60.50.50.20.3-0.3-0.50.4-0.30.1-1.30.7-2.1-2.2-0.71.2
Conditioned locomotion0.10.21.2-0.3-0.90.10.0-0.20.1-0.2-0.2-0.1-0.0-0.10.1-0.10.1-0.1-0.7-0.3-0.5-0.2-1.0-1.10.20.2
Patch foraging indifference point 0 sec0.20.31.30.11.00.20.10.4-0.1-0.1-0.10.20.3-0.10.2-0.2-0.80.20.90.00.41.01.11.1-0.90.8
Patch foraging indifference point AUC0.30.52.1-0.5-0.60.60.3-0.0-0.2-0.5-0.50.10.30.20.4-0.41.40.2-0.7-1.0-0.8-0.6-1.4-1.30.8-0.6
Delay disc. indifference point, 0s delay0.20.20.60.2-0.3-0.5-0.4-0.1-0.10.60.50.1-0.1-0.4-0.30.3-0.70.1-0.3-0.1-0.3-0.0-0.7-0.70.80.1
Delay disc. indifference point, 16s delay0.40.41.50.30.50.30.30.6-0.6-0.1-0.10.50.60.30.3-0.3-1.20.80.8-1.0-0.51.2-0.4-0.4-0.61.2
Delay disc. indifference point, 2s delay0.70.85.2-0.6-0.30.50.50.5-0.8-0.5-0.50.80.70.50.5-0.50.50.8-0.1-0.2-1.50.4-2.3-2.20.00.5
Delay disc. indifference point, 24s delay0.60.61.40.7-0.8-1.1-0.9-0.80.61.00.9-0.8-0.8-0.9-0.90.9-0.2-0.7-0.90.20.6-1.00.20.21.2-0.8
Delay disc. indifference point, 4s delay1.11.13.00.6-1.2-1.3-1.1-1.11.01.31.2-0.8-1.1-1.1-1.11.10.5-1.1-1.30.70.4-1.4-0.3-0.21.7-1.2
Delay disc. indifference point, 8s delay0.30.40.90.7-0.7-0.9-0.7-0.60.41.00.8-0.5-0.6-0.7-0.70.7-0.8-0.4-0.70.40.4-0.50.00.00.8-0.1
Indifference point function ln k0.40.72.3-0.81.50.60.51.1-1.1-0.6-0.51.00.90.60.6-0.6-0.11.11.5-0.3-0.21.10.70.8-0.90.7
Indifference point function log k0.40.72.3-0.81.50.60.51.1-1.1-0.6-0.51.00.90.60.6-0.6-0.11.11.5-0.3-0.21.10.70.8-0.90.7
Patch foraging total patch changes 0 sec0.20.31.30.30.7-0.0-0.20.20.10.10.1-0.00.1-0.3-0.10.1-1.00.00.70.30.60.91.11.1-0.70.7
Patch foraging total patch changes 12 sec0.81.11.4-1.10.51.21.01.0-1.1-1.1-1.11.11.10.91.2-1.20.21.10.7-1.0-1.21.0-1.0-1.0-0.91.0
Patch foraging total patch changes 18 sec1.01.63.4-0.91.11.21.11.3-1.2-1.2-1.51.21.41.01.4-1.4-0.41.41.4-1.3-1.01.8-0.5-0.5-1.81.7
Patch foraging total patch changes 24 sec0.81.42.9-1.11.21.71.21.2-1.0-1.5-1.51.11.41.11.5-1.51.21.11.1-1.5-1.00.9-0.4-0.3-0.80.4
Patch foraging total patch changes 6 sec0.20.32.40.60.2-0.3-0.4-0.10.40.50.3-0.3-0.2-0.4-0.20.2-1.6-0.20.30.30.60.60.80.7-0.40.8
Patch foraging time to switch 0 sec0.61.24.61.4-0.7-1.4-1.0-0.91.21.41.0-1.0-1.1-0.9-1.01.0-2.1-1.0-0.51.61.20.01.00.9-0.60.8
Patch foraging water rate 0 sec1.53.15.5-2.32.32.31.82.0-2.2-2.1-1.72.12.11.71.6-1.62.22.01.9-2.3-1.50.7-0.10.1-0.1-0.6
Patch foraging water rate 12 sec1.83.86.5-2.42.42.12.12.3-2.5-2.1-2.12.42.32.12.1-2.11.32.52.2-1.6-1.91.6-0.6-0.5-1.30.5
Patch foraging water rate 18 sec3.14.87.9-2.81.92.52.22.3-2.8-2.5-2.32.62.52.22.2-2.22.22.61.8-2.5-2.61.2-1.7-1.6-0.80.3
Patch foraging water rate 24 sec1.92.64.6-2.12.01.81.61.8-2.1-1.8-1.62.01.81.61.6-1.62.01.91.7-1.9-1.50.8-0.4-0.2-0.2-0.4
Patch foraging water rate 6 sec3.85.68.8-2.82.53.02.52.5-2.7-2.9-2.72.72.72.42.5-2.52.72.62.3-2.5-2.31.4-1.0-0.8-1.20.1
Seeking ratio, delayed vs. immediate footshock0.30.31.7-1.30.70.50.40.6-0.4-0.3-0.40.40.40.50.6-0.6-0.30.50.8-0.4-0.20.80.20.2-0.90.6
Distance traveled before self-admin1.62.13.6-0.51.31.41.61.7-1.4-1.4-1.31.61.51.61.5-1.5-0.11.41.6-1.5-1.51.9-1.0-1.0-1.81.5
Distance traveled after self-admin1.31.52.8-0.91.51.31.41.6-1.2-1.1-0.91.61.41.51.2-1.20.21.31.6-1.5-1.31.7-0.4-0.4-1.11.0
Extensor digitorum longus weight0.21.03.1-0.61.80.90.91.1-0.8-0.8-0.90.90.80.91.0-1.00.50.81.5-1.4-0.00.71.31.4-0.7-0.2
Bone: elastic displacement0.10.20.4-0.10.20.50.40.3-0.4-0.6-0.70.40.40.40.5-0.50.40.40.1-0.3-0.50.0-0.5-0.5-0.2-0.3
Bone: elastic work0.91.13.0-1.01.51.00.90.9-0.9-1.1-1.20.90.80.91.1-1.11.70.71.0-1.5-0.2-0.41.11.20.2-1.3
Bone: endosteal estimation0.20.51.5-0.80.60.70.80.5-0.6-0.8-0.90.60.50.71.0-1.01.20.40.3-0.9-0.4-0.60.10.20.2-0.9
Bone: endosteal perimeter0.30.64.1-0.3-0.00.40.4-0.0-0.2-0.4-0.60.30.00.40.6-0.62.0-0.1-0.4-0.6-0.2-1.5-0.00.01.1-1.9
Epididymis fat weight6.823.131.05.5-4.5-5.1-5.6-5.35.45.25.4-5.4-5.3-5.5-5.65.6-2.8-5.4-4.64.05.3-4.23.12.94.0-2.7
Delta time in closed arm before/after self-admin1.51.43.0-0.1-1.1-1.3-1.3-1.31.21.41.5-1.2-1.3-1.3-1.41.4-0.3-1.2-1.31.71.1-1.20.40.41.4-0.9
Delta time in open arm before/after self-admin2.22.23.8-1.00.91.51.61.5-1.5-1.5-1.71.61.51.51.7-1.70.61.51.1-1.2-2.01.4-1.8-1.8-1.61.1
Diff in mean of infusions in LGA sessions12.014.620.03.5-3.9-4.5-4.2-4.34.44.34.4-4.5-4.4-4.2-4.24.2-3.2-4.3-3.84.44.0-3.02.11.82.7-1.1
Delay discount exponential model param0.50.51.1-0.61.01.00.80.7-0.4-1.1-0.90.50.60.80.8-0.80.40.50.9-0.3-0.10.60.60.6-1.10.2
Extinction: sum of active levers before priming0.30.32.00.5-0.7-0.2-0.4-0.30.30.10.4-0.3-0.2-0.4-0.40.4-1.4-0.1-0.40.20.00.5-0.4-0.6-0.41.2
Active lever presses in extinction session 60.30.31.90.2-0.6-0.2-0.3-0.30.50.30.6-0.2-0.2-0.4-0.40.4-1.4-0.4-0.31.1-0.00.5-0.6-0.7-0.41.0
Bone: final force2.74.38.6-2.42.92.32.42.4-2.2-2.4-2.52.22.22.32.5-2.51.22.12.5-2.3-1.41.20.60.7-1.4-0.1
Bone: final moment2.84.58.9-2.33.02.42.42.5-2.3-2.5-2.52.32.32.32.5-2.51.12.22.6-2.4-1.41.30.60.7-1.60.0
Food consumed during 24 hour testing period0.50.62.7-0.71.50.60.50.8-0.5-0.6-0.50.50.60.60.5-0.51.60.51.1-0.80.10.21.21.3-0.0-0.6
Glucose0.10.10.3-0.40.30.30.20.4-0.5-0.3-0.20.40.40.20.2-0.20.00.60.4-0.4-0.40.6-0.3-0.3-0.40.5
Heart weight1.82.85.7-1.52.41.61.62.0-1.8-1.6-1.71.81.81.51.8-1.8-0.11.92.4-1.4-1.02.20.50.5-1.91.5
Delay discount hyperbolic model param0.50.51.2-0.51.10.90.70.7-0.3-1.0-0.80.40.60.70.7-0.70.40.41.0-0.40.10.51.01.0-1.00.1
Intermittent access intake day 1-15 change3.16.39.1-2.22.12.83.02.7-2.6-2.9-3.02.52.82.82.7-2.70.82.72.4-2.7-2.72.4-1.8-1.8-2.41.8
Intermittent access intake escalation2.55.27.7-2.02.02.62.72.5-2.4-2.7-2.82.22.62.62.5-2.50.72.42.3-2.6-2.32.2-1.4-1.4-2.21.6
Intermittent access intake escalation 22.32.64.0-1.71.41.82.01.8-1.7-1.8-1.91.71.81.91.7-1.70.71.71.6-1.9-1.71.5-1.2-1.1-1.30.9
Intermitt. access day 1 inactive lever presses0.20.71.10.5-0.9-0.8-1.1-1.00.90.90.7-1.0-0.8-1.0-0.80.8-0.2-0.9-0.90.71.0-0.90.60.50.7-0.6
Intermitt. access day 15 inactive lever presses0.20.32.1-0.6-0.6-0.3-0.4-0.1-0.30.20.10.2-0.0-0.3-0.20.2-0.40.3-0.40.9-0.60.1-1.5-1.4-0.10.4
Intermitt. access escalation Index0.10.11.30.20.10.10.10.00.1-0.2-0.1-0.10.10.00.2-0.21.1-0.2-0.0-0.6-0.0-0.40.30.30.4-0.6
Intermittent access day 1 total infusions0.61.04.50.2-1.5-0.8-0.5-0.40.20.70.7-0.1-0.4-0.6-0.60.6-2.1-0.0-0.80.9-0.60.8-1.6-1.8-0.42.0
Intermittent access day 15 total infusions1.52.24.9-1.10.41.31.61.4-1.4-1.4-1.51.41.51.41.4-1.4-0.71.51.0-1.3-1.91.9-1.9-2.0-1.72.2
Intermittent access terminal intake (last 3 days)2.02.77.0-1.20.31.41.61.5-1.6-1.5-1.61.61.61.61.5-1.5-0.01.70.8-1.4-2.41.8-2.6-2.6-1.42.0
Intermittent access total infusions1.41.65.1-0.8-0.10.71.01.0-1.1-0.8-0.91.21.10.90.9-0.9-0.91.30.5-0.3-1.81.7-2.2-2.3-1.42.2
Intermittent access day 1 locomotion1.62.05.21.1-2.3-1.6-1.7-1.71.51.41.5-1.5-1.6-1.8-1.31.3-1.6-1.4-1.91.70.9-0.8-0.4-0.60.60.4
Intermittent access day 15 total locomotion0.61.03.2-1.6-0.41.20.90.5-0.7-1.2-1.30.60.90.71.2-1.20.40.7-0.1-0.2-1.40.6-1.7-1.8-0.90.9
Intermittent access total locomotion0.30.42.1-0.9-1.00.40.1-0.1-0.1-0.6-0.50.10.2-0.10.5-0.50.10.1-0.70.3-0.80.1-1.4-1.4-0.40.5
Intermittent access standard deviation2.14.49.9-1.50.62.02.11.9-1.9-2.0-2.01.82.22.01.9-1.9-1.22.21.4-1.7-2.52.6-2.6-2.7-2.63.2
Left kidney weight0.52.14.3-1.40.82.01.81.3-1.1-1.9-1.91.31.41.71.9-1.92.11.00.7-1.4-1.80.2-1.4-1.3-0.6-0.5
Right kidney weight1.15.17.6-2.52.22.72.72.5-2.2-2.7-2.82.42.42.72.7-2.71.92.12.1-2.1-2.51.4-1.3-1.2-1.70.3
Cocaine induced anxiety0.30.51.21.1-0.9-0.6-0.6-0.80.70.60.5-0.7-0.8-0.6-0.60.60.6-0.7-1.00.20.3-1.0-0.3-0.30.9-0.9
Post-drug Anxiety0.50.60.8-0.10.60.70.90.8-0.9-0.8-0.80.90.80.80.9-0.90.20.90.7-0.7-0.90.7-0.6-0.6-0.80.6
Baseline Anxiety1.92.24.3-1.91.91.31.31.8-1.6-1.3-1.41.61.61.41.5-1.5-0.41.72.1-1.1-0.91.90.50.4-1.81.6
Tail length0.83.37.7-2.00.62.01.71.5-1.8-2.0-1.91.91.81.82.0-2.02.01.60.6-1.5-2.60.8-2.8-2.6-0.90.4
Length with tail0.31.34.9-1.61.11.31.11.1-1.2-1.2-1.21.41.11.21.3-1.32.21.00.7-1.4-1.2-0.1-0.5-0.40.1-0.9
Length without tail0.51.75.1-1.71.61.61.41.4-1.4-1.4-1.41.51.31.41.4-1.42.21.11.1-1.3-1.0-0.10.20.30.1-1.1
Times rat made contact with spout4.04.66.32.2-2.4-2.3-2.4-2.52.42.32.4-2.5-2.4-2.4-2.42.4-0.2-2.4-2.52.01.9-2.20.40.42.2-1.5
Lifetime Intake1.01.25.3-0.8-0.00.50.80.8-0.9-0.6-0.71.00.90.70.7-0.7-1.41.10.5-0.0-1.41.8-1.7-1.8-1.32.3
Liver weight, left0.61.02.8-1.01.71.11.01.1-0.8-1.1-1.10.90.91.11.2-1.20.90.81.3-0.5-0.30.30.80.9-0.6-0.5
Liver weight, right0.20.32.20.10.7-0.1-0.20.00.10.10.2-0.2-0.2-0.1-0.10.10.4-0.20.4-0.30.7-0.41.41.50.2-0.8
Locomotor activity2.53.97.1-2.12.22.52.22.2-2.1-2.5-2.22.12.22.22.2-2.21.62.12.1-2.7-1.81.4-0.4-0.4-1.20.4
Locomotor testing distance4.78.512.7-3.23.13.63.23.3-3.2-3.5-3.33.33.33.23.2-3.21.63.13.0-3.4-3.02.3-1.3-1.1-2.11.0
Locomotor testing rearing4.28.512.3-3.52.43.53.23.1-3.3-3.5-3.13.33.33.23.2-3.22.33.22.5-3.1-3.42.1-2.1-2.0-2.01.1
Locomotion in novel chamber1.21.53.11.8-1.2-1.2-1.3-1.41.51.11.0-1.5-1.4-1.3-1.21.2-0.3-1.5-1.30.81.4-1.30.90.91.1-0.9
Locomotion in novel chamber post-restriction0.61.01.9-1.10.61.20.90.9-0.8-1.2-1.10.91.11.01.0-1.00.40.90.8-0.2-1.21.1-1.4-1.3-1.00.8
Fecal boli incidents, locomotor time 10.40.51.7-0.31.1-0.00.20.8-0.60.20.10.70.40.20.3-0.3-0.50.71.2-0.90.21.11.31.2-0.71.3
Change in fecal boli incidents, locomotor task0.00.00.3-0.30.20.1-0.0-0.0-0.1-0.1-0.0-0.10.00.1-0.20.20.1-0.00.00.2-0.0-0.1-0.2-0.10.4-0.6
Time >=10cm from walls, locomotor time 10.40.41.1-0.11.00.90.60.8-0.4-0.8-0.80.50.60.60.7-0.70.80.30.9-0.9-0.20.40.70.7-0.2-0.4
Bouts of movement, locomotor time 11.51.78.12.8-1.1-1.0-1.5-1.31.50.91.3-1.3-1.1-1.4-1.51.5-1.9-1.4-1.01.41.2-0.20.50.40.30.3
Total resting periods, locomotor time 11.21.46.52.5-1.2-0.9-1.4-1.21.40.81.1-1.1-0.9-1.3-1.31.3-1.7-1.3-0.91.20.9-0.10.1-0.00.20.5
Rest time, locomotor task time 11.01.35.52.3-1.6-1.0-1.2-1.21.20.90.9-1.0-0.9-1.3-1.11.1-1.7-1.0-1.21.40.6-0.0-0.6-0.7-0.10.9
Distance moved, locomotor task time 11.72.59.8-3.11.81.61.81.7-1.6-1.7-1.81.41.41.81.9-1.92.11.51.4-1.5-1.30.2-0.10.0-0.7-0.9
Vertical activity count, locomotor time 10.20.42.4-1.60.40.70.70.6-0.9-0.7-0.50.40.60.80.7-0.70.60.90.3-0.3-0.80.2-0.6-0.5-0.2-0.2
Time >=10cm from walls, locomotor time 20.20.21.40.2-0.7-0.0-0.2-0.30.3-0.0-0.0-0.2-0.3-0.2-0.20.21.2-0.5-0.7-0.6-0.1-0.7-0.4-0.40.8-0.8
Bouts of movement, locomotor time 20.40.62.71.0-0.5-0.5-1.0-0.50.80.30.6-0.7-0.4-0.7-1.11.1-1.7-0.7-0.10.20.70.50.50.4-0.21.1
Total resting periods, locomotor time 20.40.73.31.1-0.6-0.7-1.1-0.60.80.50.9-0.8-0.5-0.9-1.31.3-1.8-0.7-0.20.20.90.50.60.5-0.11.2
Rest time, locomotor task time 20.30.42.81.5-0.3-0.3-0.5-0.30.30.30.5-0.4-0.0-0.6-0.60.6-1.7-0.10.00.50.40.70.0-0.0-0.51.2
Distance moved, locomotor task time 21.21.47.7-1.90.40.91.10.7-0.9-1.1-1.30.90.61.01.3-1.32.80.6-0.1-0.7-1.3-0.8-1.2-1.00.2-1.8
Vertical activity count, locomotor time 20.10.10.9-0.4-0.6-0.1-0.1-0.2-0.1-0.0-0.2-0.1-0.1-0.00.2-0.20.40.1-0.50.3-0.4-0.2-1.0-0.9-0.1-0.2
Light reinforcement 10.71.711.1-0.8-1.10.80.70.3-0.7-0.8-0.90.60.70.60.9-0.91.80.5-0.8-0.6-2.1-0.2-3.3-3.30.1-0.1
Light reinforcement 20.71.15.3-0.8-0.70.50.70.3-0.4-0.6-0.70.50.40.70.8-0.82.20.2-0.6-1.0-1.5-0.6-2.3-2.30.5-0.8
Bone: marrow area0.20.51.5-0.80.60.70.80.5-0.6-0.8-0.90.60.50.71.0-1.01.20.40.4-0.9-0.4-0.50.10.20.2-0.9
Bone: maximum diameter0.40.72.3-0.71.10.80.70.6-0.8-0.8-0.70.70.50.70.7-0.71.30.50.7-0.9-0.0-0.60.91.00.6-1.5
Bone: maximum force2.44.37.4-2.42.72.32.52.5-2.3-2.3-2.42.32.22.42.4-2.41.02.22.5-2.5-1.61.30.20.3-1.40.2
Bone: maximum moment2.74.77.7-2.52.82.42.52.6-2.4-2.4-2.52.42.32.42.5-2.51.12.32.5-2.5-1.71.40.10.2-1.60.3
Mean time between licks in bursts0.10.31.00.8-0.6-0.5-0.4-0.50.40.40.4-0.4-0.4-0.4-0.40.41.0-0.4-0.7-0.20.3-0.90.00.00.7-0.8
Mean num. licks in bursts0.71.12.00.7-1.3-1.1-1.1-1.11.21.11.3-1.1-1.1-1.1-1.21.2-1.4-1.1-1.11.00.8-0.70.10.10.8-0.2
Cd content in liver0.40.42.3-0.01.10.40.40.4-0.1-0.4-0.50.00.20.40.4-0.4-0.20.21.0-0.10.60.61.51.5-0.70.3
Co content in liver0.40.52.2-0.91.20.50.20.4-0.4-0.4-0.40.40.40.20.4-0.41.40.30.8-0.30.4-0.21.41.50.0-0.9
Cu content in liver0.80.92.1-1.50.41.01.00.9-1.0-1.0-0.91.00.91.01.0-1.00.70.90.6-1.4-1.20.5-1.1-1.1-0.60.5
Fe content in liver0.30.40.9-0.90.20.60.70.6-0.6-0.6-0.60.50.60.70.6-0.60.40.60.5-1.0-0.70.6-0.6-0.6-0.60.8
K content in liver0.20.20.8-0.60.30.20.20.2-0.4-0.2-0.20.30.20.20.2-0.20.60.20.1-0.7-0.1-0.60.20.30.7-0.9
Mg content in liver0.60.61.8-0.51.30.80.70.7-0.8-0.8-0.60.80.70.60.7-0.70.50.70.9-1.3-0.1-0.30.91.00.2-0.9
Mn content in liver4.85.310.2-2.53.22.62.72.6-2.5-2.7-2.72.52.42.72.7-2.72.32.32.6-2.8-1.60.70.60.8-0.8-0.9
Na content in liver2.52.75.2-1.51.42.11.91.6-1.9-2.1-1.91.81.71.91.9-1.92.31.71.1-1.9-1.80.2-1.0-0.9-0.1-0.6
Rb content in liver0.60.71.6-0.71.11.01.00.9-0.9-1.0-1.00.90.91.01.1-1.10.60.70.8-1.3-0.6-0.30.10.30.0-1.0
Se content in liver0.50.61.41.1-0.7-0.9-0.8-0.81.00.90.7-1.0-0.9-0.8-0.70.7-0.9-0.9-0.61.20.9-0.30.50.5-0.20.2
Sr content in liver0.40.41.2-0.3-0.10.50.50.4-0.4-0.5-0.50.40.50.50.5-0.5-0.10.50.20.1-0.80.7-1.1-1.1-1.00.9
Zn content in liver0.30.30.60.2-0.3-0.7-0.6-0.60.60.70.6-0.6-0.7-0.6-0.60.60.3-0.6-0.40.40.8-0.60.80.80.5-0.4
Bone: minimum diameter0.30.51.5-1.20.50.80.90.7-0.7-0.8-1.00.80.60.80.9-0.90.80.60.4-0.7-0.7-0.1-0.3-0.3-0.3-0.4
Time in familiar zone, hab. session 10.40.41.00.3-0.1-0.6-0.5-0.50.50.60.3-0.4-0.6-0.5-0.20.21.0-0.6-0.40.20.8-0.80.90.90.8-1.0
Time in novel zone, hab. session 10.40.43.30.5-0.7-0.5-0.4-0.40.50.30.6-0.4-0.5-0.5-0.70.7-1.8-0.4-0.50.70.1-0.0-0.4-0.5-0.00.3
Total zone transitions, hab. session 11.31.811.8-1.81.01.51.31.0-1.3-1.3-1.21.31.21.41.1-1.13.41.00.5-1.0-1.3-0.7-0.7-0.50.7-1.6
Total locomotion distance, hab. session 11.72.48.7-2.21.11.81.61.4-1.8-1.7-1.51.81.61.71.4-1.42.91.40.7-1.6-1.8-0.3-1.2-1.10.5-1.4
Locomotion velocity, hab. session 11.31.86.9-1.70.71.61.31.1-1.4-1.4-1.31.51.31.41.2-1.22.61.10.5-1.3-1.7-0.2-1.4-1.20.3-1.1
Time in familiar zone, hab. session 22.32.53.81.5-1.1-1.7-1.6-1.71.71.51.6-1.7-1.7-1.6-1.51.50.2-1.8-1.40.81.9-1.81.71.71.8-1.6
Time in novel zone, hab. session 21.21.22.7-0.90.81.11.01.2-1.1-1.0-1.11.21.11.01.0-1.0-0.81.21.1-0.5-1.21.5-1.0-1.0-1.61.5
Total zone transitions, hab. session 20.81.17.1-1.21.11.20.80.8-0.9-1.0-0.90.90.90.90.9-0.92.70.60.7-1.4-0.5-0.50.50.60.5-1.4
Total locomotion distance, hab. session 20.81.04.2-1.11.31.20.91.1-1.0-1.0-0.91.11.01.00.8-0.81.60.91.1-2.0-0.50.30.60.7-0.2-0.6
Locomotion velocity, hab. session 20.60.83.3-1.01.01.10.80.9-0.9-0.9-0.80.90.90.80.7-0.71.80.70.8-1.8-0.5-0.10.30.40.2-0.8
Novel to familiar place preference ratio1.01.11.70.9-1.1-1.2-1.1-1.21.11.11.1-1.0-1.2-1.2-1.11.10.0-1.2-1.31.00.8-1.30.10.11.1-1.2
Novelty place preference1.01.11.71.0-1.2-1.2-1.1-1.21.11.11.1-1.1-1.2-1.3-1.11.1-0.3-1.2-1.31.20.8-1.1-0.00.00.9-1.0
Time in novel zone, NPP test0.91.01.51.0-1.1-1.2-1.1-1.11.11.01.0-1.1-1.2-1.2-1.11.1-0.6-1.1-1.11.10.8-0.90.10.10.7-0.6
Total zone transitions, NPP test0.60.84.6-0.30.40.1-0.3-0.20.20.10.3-0.2-0.2-0.1-0.40.42.1-0.4-0.2-0.30.6-1.41.31.31.7-2.0
Total locomotion distance, NPP test0.50.85.2-1.10.70.90.50.6-0.7-0.7-0.40.70.60.60.4-0.42.30.40.3-1.4-0.5-0.80.20.31.1-1.5
Locomotion velocity, NPP test0.70.96.6-1.20.71.00.60.6-0.7-0.8-0.50.80.70.70.4-0.42.60.40.2-1.3-0.6-1.00.00.11.2-1.8
Intraocular pressure0.91.32.4-0.91.31.31.21.2-1.1-1.3-1.31.11.31.21.2-1.20.51.21.4-0.8-1.01.3-0.4-0.4-1.50.8
Delta distance traveled before/after self-admin0.20.20.7-0.5-0.3-0.3-0.4-0.40.30.40.5-0.2-0.3-0.4-0.50.50.3-0.4-0.50.40.2-0.50.10.10.8-0.5
Delta ambulatory time before/after self-admin0.60.72.7-1.60.91.00.90.9-1.0-0.9-0.81.01.00.80.8-0.81.01.00.8-1.0-0.80.5-0.2-0.1-0.20.1
Parametrial fat weight3.27.610.32.7-3.1-3.0-3.0-3.03.13.13.1-2.9-3.0-3.1-3.13.1-1.0-3.2-3.13.22.3-2.60.60.52.9-1.6
Pavlov. Cond. lever latency0.70.93.00.9-1.7-0.9-0.8-0.90.70.70.7-0.7-0.7-1.0-0.70.7-0.1-0.6-1.31.1-0.2-0.1-1.7-1.70.30.5
Pavlov. Cond. magazine entry latency0.30.32.50.10.6-0.10.10.10.20.10.2-0.1-0.1-0.0-0.20.2-0.8-0.10.6-0.60.8-0.01.61.5-0.10.1
Pavlov. Cond. change in total contacts1.11.23.1-1.11.81.11.11.3-1.1-1.0-0.81.11.11.10.9-0.90.11.11.7-1.5-0.31.01.11.1-0.90.5
Pavlov. Cond. index score0.50.72.9-0.71.40.70.70.8-0.5-0.6-0.50.60.60.70.5-0.50.10.41.1-1.20.3-0.01.71.7-0.2-0.5
Pavlov. Cond. latency score0.60.84.1-0.71.60.70.70.8-0.5-0.5-0.50.50.50.70.5-0.50.10.41.2-1.10.5-0.12.02.0-0.1-0.7
Pavlov. Cond. lever contacts0.80.92.8-1.01.71.00.91.0-0.8-0.8-0.70.80.81.00.7-0.70.30.71.3-1.30.10.11.61.6-0.2-0.6
Pavlov. Cond. magazine entry number0.40.51.40.5-1.2-0.7-0.8-0.80.40.60.5-0.5-0.6-0.7-0.60.60.4-0.4-1.11.1-0.2-0.4-1.2-1.20.7-0.3
Pavlov. Cond. intertrial magazine entries1.21.42.5-1.20.91.11.21.3-1.4-1.1-1.21.41.21.31.2-1.20.81.41.0-1.0-1.61.3-1.3-1.2-1.00.6
Pavlov. Cond. lever-magazine prob. diff.0.40.52.0-0.71.20.60.70.7-0.5-0.5-0.40.50.50.70.5-0.50.10.41.0-1.20.2-0.11.41.4-0.1-0.5
Pavlov. Cond. response bias0.50.72.0-0.61.40.70.80.9-0.5-0.6-0.50.60.60.80.6-0.6-0.40.51.3-1.20.20.51.41.4-0.70.2
Pavlov. Cond. lever latency0.40.51.71.2-1.0-0.6-0.5-0.50.60.60.6-0.5-0.5-0.4-0.60.6-1.3-0.5-0.50.20.00.4-0.8-0.9-0.51.1
Pavlov. Cond. magazine entry latency2.12.65.30.4-2.3-1.7-1.9-2.01.71.71.8-1.8-1.7-2.0-1.71.7-1.1-1.7-2.11.91.1-1.3-0.3-0.41.4-0.4
Pavlov. Cond. change in total contacts0.30.63.4-0.61.00.1-0.10.1-0.2-0.1-0.00.10.0-0.10.0-0.00.90.10.40.00.8-0.71.71.80.9-1.5
Pavlov. Cond. index score0.70.92.0-0.2-0.5-0.9-1.0-1.00.90.80.9-0.9-1.0-1.1-0.80.80.3-0.9-0.91.01.1-1.21.11.11.4-1.4
Pavlov. Cond. latency score1.01.32.20.0-0.9-1.1-1.3-1.31.11.11.1-1.2-1.2-1.4-1.11.1-0.0-1.2-1.11.31.3-1.31.01.01.5-1.3
Pavlov. Cond. lever contacts0.40.62.2-1.21.00.40.30.4-0.5-0.4-0.40.40.40.30.5-0.51.50.40.5-0.30.2-0.61.11.30.7-1.4
Pavlov. Cond. magazine entry number3.03.75.6-0.72.22.12.22.3-2.1-2.1-2.02.12.22.42.0-2.00.52.22.3-2.2-1.82.1-0.7-0.6-2.21.5
Pavlov. Cond. intertrial magazine entries2.43.65.1-1.72.12.22.22.2-2.2-2.2-2.12.22.22.32.1-2.11.62.12.0-1.6-1.91.5-0.8-0.7-1.40.7
Pavlov. Cond. lever-magazine prob. diff.0.81.11.90.0-0.6-1.0-1.1-1.11.00.90.9-1.0-1.1-1.2-0.90.90.2-1.0-0.91.11.3-1.31.21.21.4-1.4
Pavlov. Cond. response bias0.20.31.8-0.80.1-0.1-0.2-0.20.10.10.1-0.1-0.2-0.3-0.00.01.0-0.2-0.20.40.4-0.90.70.81.0-1.3
Time in closed arm before self-admin0.20.31.6-0.70.70.00.10.3-0.2-0.0-0.30.20.00.10.2-0.20.60.10.5-1.20.4-0.31.21.20.1-0.6
Time in closed arm after self-admin0.50.51.3-0.7-0.3-0.8-0.6-0.50.40.70.6-0.5-0.7-0.6-0.60.60.7-0.5-0.5-0.10.8-1.11.01.01.1-1.1
Time in open arm before self-admin4.54.98.72.8-1.3-2.4-2.4-2.12.42.22.5-2.3-2.3-2.4-2.62.6-1.8-2.3-1.41.72.9-1.52.52.51.7-0.9
Time in open arm after self-admin0.30.32.01.40.3-0.4-0.2-0.00.20.30.4-0.1-0.1-0.2-0.30.3-1.4-0.10.40.10.50.70.60.6-0.60.8
Bone: periosteal estimation1.02.23.6-1.61.61.81.81.6-1.6-1.8-1.91.71.51.71.9-1.91.41.51.4-1.8-1.20.3-0.1-0.0-0.6-0.5
Bone: periosteal perimeter0.61.03.9-1.10.91.11.10.8-1.0-1.2-1.31.00.81.01.2-1.22.00.70.5-1.0-0.7-0.70.00.10.3-1.5
Bone: post-yield work0.71.02.9-1.20.70.80.91.1-1.0-0.7-0.71.10.90.90.9-0.9-0.61.11.0-0.6-1.11.5-0.8-0.9-1.41.7
Progressive ratio test 1 active lever presses1.11.43.5-0.70.31.01.11.0-1.0-1.1-1.11.11.21.01.1-1.1-0.71.10.7-0.7-1.51.7-1.6-1.7-1.51.9
Progressive ratio test 1 breakpoint1.11.33.3-0.60.31.01.11.0-1.0-1.1-1.11.11.20.91.1-1.1-0.71.10.7-0.7-1.51.6-1.5-1.6-1.41.8
Progressive ratio test 1 inactive lever presses0.10.10.7-0.3-0.4-0.1-0.1-0.1-0.1-0.00.10.10.1-0.1-0.10.10.20.1-0.30.6-0.4-0.0-0.9-0.80.40.1
Progressive ratio test 2 active lever presses0.30.31.0-1.00.10.30.50.6-0.6-0.4-0.50.70.50.40.4-0.4-0.30.70.3-0.3-0.80.8-0.6-0.7-0.50.9
Progressive ratio test 2 breakpoint0.30.41.2-1.10.20.40.60.6-0.7-0.5-0.50.80.60.40.4-0.4-0.10.70.3-0.3-0.90.8-0.7-0.8-0.40.8
Progressive ratio test 2 inactive lever presses1.01.66.8-1.2-0.10.80.90.9-1.3-1.0-0.91.31.10.80.8-0.8-0.21.30.3-0.1-2.01.4-2.6-2.6-0.81.7
Incentive Sensitization - Responses0.10.11.0-1.0-0.1-0.10.10.1-0.30.1-0.00.3-0.0-0.1-0.10.10.60.2-0.10.0-0.3-0.1-0.2-0.20.4-0.2
Incentive Sensitization - Breakpoint0.10.11.3-1.1-0.1-0.10.10.2-0.40.0-0.10.40.00.0-0.00.00.60.3-0.10.0-0.4-0.1-0.3-0.30.3-0.1
Sum of active levers in priming session hrs 5-63.02.89.22.7-1.8-1.5-1.8-1.71.91.41.7-1.8-1.5-1.8-1.71.7-3.0-1.7-1.42.21.5-0.10.20.0-0.11.0
Progressive ratio0.40.62.50.40.80.40.30.6-0.3-0.4-0.40.30.50.30.3-0.3-1.30.61.00.00.11.50.70.7-1.51.6
Food seeking constrained by brief footshock0.10.10.40.6-0.4-0.1-0.2-0.20.10.00.2-0.1-0.1-0.2-0.20.2-0.7-0.1-0.30.1-0.20.1-0.4-0.4-0.10.6
Seeking ratio, punishment vs. effort0.20.31.3-0.2-1.0-0.3-0.2-0.40.20.30.4-0.2-0.4-0.2-0.30.30.4-0.3-1.00.1-0.4-0.8-1.1-1.10.9-0.5
Retroperitoneal fat weight4.117.729.63.9-5.1-4.2-4.5-4.94.54.34.4-4.4-4.6-4.4-4.44.40.3-4.8-5.43.93.1-5.20.10.05.0-4.1
Reaction time number correct0.10.30.8-0.70.90.40.50.5-0.7-0.3-0.30.60.40.40.5-0.50.70.50.6-0.4-0.1-0.20.50.60.0-0.8
Reaction time mean minus median0.51.33.41.5-1.4-1.4-1.2-1.21.21.31.2-1.2-1.3-1.2-1.11.1-1.8-1.1-1.11.41.0-0.60.0-0.00.00.3
Reaction time mean minus median AUC0.92.33.91.9-2.0-1.6-1.7-1.81.81.51.5-1.7-1.7-1.6-1.51.5-1.8-1.7-1.71.91.3-1.10.10.00.6-0.0
Reaction time num false alarms2.02.812.1-1.9-0.31.61.51.0-1.4-1.5-1.51.51.41.51.5-1.52.21.2-0.2-0.7-2.70.0-3.5-3.4-0.20.1
Reaction time num false alarms AUC2.03.111.6-2.0-0.11.81.61.3-1.6-1.6-1.71.71.61.61.7-1.71.71.50.2-0.8-2.90.6-3.4-3.4-0.70.7
Reaction time trials correct on left0.10.30.8-0.70.90.40.50.5-0.7-0.3-0.30.60.40.40.5-0.50.70.50.6-0.4-0.1-0.20.50.60.0-0.8
Reaction time trials on left0.10.30.8-0.70.90.30.40.5-0.6-0.3-0.30.50.30.40.4-0.40.70.50.6-0.4-0.1-0.20.50.60.0-0.8
Reaction time mean1.22.05.41.5-2.3-1.8-1.6-1.61.41.51.5-1.4-1.5-1.5-1.51.5-1.3-1.3-1.91.10.6-1.1-0.8-1.00.70.2
Reaction time mean AUC1.62.55.51.8-2.4-2.0-1.8-1.81.61.81.8-1.6-1.8-1.7-1.81.8-1.3-1.6-2.01.31.0-1.3-0.4-0.51.0-0.1
Median of all reaction times0.91.34.41.1-2.1-1.4-1.3-1.31.01.21.2-1.0-1.2-1.2-1.21.2-0.9-1.0-1.70.60.3-0.9-1.0-1.10.70.3
Reaction time omissions1.82.64.71.8-2.2-2.0-1.6-1.81.72.01.9-1.8-1.9-1.6-1.81.8-1.1-1.7-2.01.81.1-1.5-0.1-0.21.1-0.5
Reaction time false alarm rate1.31.910.2-1.3-0.71.21.00.7-0.9-1.1-1.11.01.11.11.0-1.01.20.9-0.4-0.4-2.30.3-3.2-3.2-0.30.7
Reaction time premature initiation rate0.20.30.50.7-0.7-0.2-0.6-0.60.60.30.6-0.6-0.5-0.7-0.60.6-0.3-0.6-0.70.30.4-0.50.0-0.00.6-0.3
Reaction time premature initiations0.00.10.50.1-0.10.1-0.2-0.20.1-0.00.2-0.1-0.1-0.3-0.20.20.2-0.1-0.2-0.00.2-0.50.30.30.5-0.7
Std. dev. reaction times0.91.73.61.6-1.9-1.6-1.4-1.51.41.41.4-1.3-1.5-1.4-1.41.4-1.7-1.2-1.61.40.9-0.9-0.2-0.40.40.3
Reaction time trials completed0.10.30.8-0.70.90.30.40.5-0.6-0.3-0.30.50.30.40.4-0.40.70.50.6-0.4-0.1-0.20.50.60.0-0.8
Reaction time trials AUC0.30.61.3-1.11.20.70.90.9-1.1-0.7-0.70.90.80.80.8-0.80.90.90.9-0.8-0.60.00.20.3-0.2-0.7
Run reversals in cocaine runway, females0.30.32.0-0.5-0.30.10.20.2-0.4-0.3-0.20.30.10.20.2-0.21.40.3-0.3-0.3-0.7-0.4-0.9-0.90.5-0.5
Run reversals in cocaine runway, males0.80.81.81.0-1.4-0.9-0.9-1.00.60.90.8-0.6-0.8-0.8-1.01.00.3-0.7-1.30.70.2-1.1-0.7-0.81.1-0.5
Latency to leave start box in cocaine runway1.21.34.20.6-0.8-1.0-1.0-1.01.21.01.0-1.0-1.2-1.1-1.01.00.9-1.4-1.10.31.0-1.80.90.91.7-2.0
Latency to leave start box in cocaine runway, F1.41.64.90.3-0.7-1.1-1.1-1.11.21.11.2-1.0-1.3-1.1-1.21.21.1-1.4-1.10.31.2-2.01.21.22.0-2.2
Latency to leave start box in cocaine runway, M0.20.20.70.9-0.5-0.4-0.4-0.50.60.40.3-0.6-0.5-0.5-0.20.2-0.1-0.7-0.60.30.3-0.50.10.10.3-0.5
Std. dev. time between licks in bursts0.81.12.6-0.11.21.11.31.2-1.2-1.1-1.21.21.21.31.2-1.21.01.21.1-1.6-1.00.8-0.3-0.3-0.70.3
Total sessions with >9 infusions0.40.53.0-0.2-0.30.30.40.2-0.1-0.4-0.40.20.40.10.3-0.3-1.60.30.10.5-0.61.2-0.9-1.0-1.01.7
Short access day 1 total inactive lever presses0.50.72.00.6-1.4-0.7-1.0-1.00.90.70.7-0.8-0.8-1.0-0.90.9-0.3-0.9-1.30.90.2-0.7-0.7-0.70.8-0.3
Short access day 10 total inactive lever presses0.10.20.40.2-0.2-0.6-0.6-0.40.30.50.5-0.4-0.4-0.5-0.60.6-0.4-0.3-0.20.30.6-0.40.50.50.2-0.3
Short access day 1 total infusions0.20.32.0-0.30.00.10.20.4-0.2-0.3-0.20.30.40.20.2-0.2-1.40.40.40.0-0.51.1-0.4-0.5-0.81.4
Short access day 10 total infusions1.41.85.3-1.1-0.11.21.21.0-1.0-1.3-1.31.11.31.01.3-1.3-0.51.10.4-0.2-1.91.7-2.2-2.3-1.62.0
Short access total infusions0.50.74.5-0.1-0.6-0.2-0.00.00.00.10.10.10.2-0.1-0.10.1-2.10.2-0.00.7-0.51.4-0.9-1.1-0.92.1
Short access day 1 locomotion0.20.31.30.1-1.1-0.2-0.2-0.30.30.1-0.1-0.4-0.0-0.3-0.20.2-0.8-0.2-0.70.3-0.40.2-1.0-1.1-0.20.9
Short access day 10 total locomotion0.10.10.5-0.7-0.50.2-0.2-0.30.3-0.4-0.2-0.30.0-0.40.2-0.2-0.5-0.1-0.30.70.10.3-0.1-0.2-0.50.7
Short access total locomotion0.30.41.5-0.0-1.2-0.2-0.4-0.60.60.1-0.0-0.6-0.3-0.6-0.10.1-1.2-0.5-0.80.8-0.00.4-0.8-0.9-0.61.1
One hour access (0.3 mA shock)1.21.43.2-1.60.70.91.31.3-1.5-1.0-1.01.51.21.21.0-1.00.81.40.8-0.9-1.81.0-1.6-1.6-0.40.7
Compulsive drug intake3.94.67.32.4-1.7-2.4-2.4-2.22.52.32.7-2.3-2.4-2.2-2.52.5-1.6-2.4-1.71.72.6-1.62.01.81.8-0.9
One hour access (shock baseline)2.64.07.1-2.61.32.02.22.1-2.4-1.9-2.22.32.21.92.0-2.01.42.31.4-1.5-2.71.6-2.2-2.1-1.21.1
Social response proportion2.42.83.81.9-1.6-1.8-1.8-1.91.91.81.8-1.9-1.8-1.8-1.91.9-0.7-1.8-1.71.81.8-1.51.11.01.4-0.9
Social responses0.30.41.7-0.7-0.00.70.50.3-0.6-0.7-0.70.50.70.40.5-0.51.30.5-0.1-0.3-0.9-0.4-0.9-0.90.4-0.7
Social time0.71.02.40.7-1.5-1.0-1.0-1.10.80.90.9-0.9-1.0-1.0-1.01.00.1-0.9-1.51.60.2-1.1-0.8-0.81.0-0.7
Soleus weight0.10.42.2-0.5-0.50.40.30.0-0.2-0.2-0.30.20.10.40.3-0.31.5-0.0-0.6-0.2-0.8-0.9-1.2-1.20.9-1.1
Bone: stiffness2.43.95.8-2.32.42.22.32.4-2.3-2.1-2.02.32.32.32.1-2.10.42.22.3-1.9-1.81.7-0.3-0.2-1.70.9
Tibialis anterior weight0.20.85.20.80.6-0.6-0.7-0.30.70.70.5-0.6-0.7-0.6-0.60.6-0.5-0.70.3-0.21.5-0.22.32.30.3-0.5
Time to tail flick, vehicle, before self-admin3.33.55.52.2-2.1-1.8-2.0-2.32.11.61.6-2.1-2.1-2.1-1.81.8-0.1-2.2-2.41.71.7-2.20.70.71.9-1.7
Time to tail flick, vehicle, after self-admin2.23.07.11.3-1.9-1.9-2.1-2.01.81.82.0-1.9-1.9-2.2-1.91.9-1.7-1.7-1.82.71.6-1.20.40.31.1-0.3
Time to tail flick, test, before self-admin0.60.63.5-0.7-0.30.70.40.1-0.3-0.8-0.80.20.40.50.5-0.51.90.2-0.5-0.2-1.1-0.7-1.5-1.40.5-0.9
Time to tail flick, test, after self-admin0.20.21.0-0.30.60.20.00.1-0.2-0.10.1-0.00.20.00.1-0.10.10.30.5-0.80.5-0.01.01.00.1-0.1
Delta time to tail flick, vehicle, before/after SA1.51.52.9-1.61.31.31.11.3-1.3-1.2-1.01.31.31.11.1-1.1-0.71.41.5-0.2-1.01.7-0.5-0.5-1.71.5
Delta time to tail flick, test, before/after SA1.31.36.91.00.2-1.0-0.9-0.60.71.11.2-0.8-0.9-1.0-1.01.0-1.2-0.70.2-0.52.0-0.32.62.50.6-0.2
Tibia length4.311.921.4-4.12.73.94.03.4-3.9-4.0-3.93.93.63.93.9-3.94.63.52.4-3.6-4.11.0-2.8-2.6-1.0-0.6
Ambulatory time before self-admin1.11.73.5-0.11.21.21.41.6-1.2-1.1-1.11.51.31.41.3-1.3-0.41.31.5-1.6-1.31.9-0.8-0.8-1.71.5
Ambulatory time after self-admin0.60.81.7-0.41.30.80.91.2-0.9-0.6-0.41.31.01.00.6-0.60.10.91.3-1.3-0.81.3-0.1-0.1-0.50.7
Bone: tissue strength1.21.22.8-1.70.81.11.21.1-1.1-1.2-1.21.11.11.21.2-1.21.21.00.8-1.1-1.40.5-1.1-1.0-0.60.1
Total heroin consumption2.12.59.02.4-1.4-1.6-1.7-1.51.71.61.7-1.6-1.5-1.7-1.71.7-3.0-1.5-1.02.11.6-0.00.60.5-0.20.9
Bone: trabecular number1.01.76.6-1.02.40.70.71.2-0.8-0.7-0.70.70.80.70.7-0.7-1.31.02.2-0.90.71.32.52.6-1.30.7
Bone: trabecular spacing2.33.010.11.3-3.2-1.1-1.0-1.81.31.21.1-1.3-1.2-1.1-1.21.21.0-1.4-2.91.7-0.5-1.9-3.0-3.01.8-1.0
Bone: trabecular thickness2.12.66.0-1.82.31.51.31.8-1.5-1.5-1.51.41.61.41.5-1.5-1.11.72.4-1.3-0.52.21.01.0-2.21.6
Bone: trabecular tissue density0.40.62.9-0.5-1.10.1-0.0-0.3-0.30.10.30.20.10.1-0.30.31.20.1-1.00.5-0.9-0.8-1.7-1.71.0-0.5
Water consumed over 24 hours0.20.30.9-0.60.90.40.30.5-0.3-0.4-0.40.30.50.40.4-0.40.80.40.8-0.70.00.30.70.8-0.1-0.2
Number of responses in last shaping day1.41.52.8-0.81.61.11.51.5-1.3-1.1-1.41.31.41.51.4-1.40.51.31.7-1.6-1.01.3-0.1-0.1-1.10.6