Tamm41

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Tamm41 0.24 0.14 0.0e+00 0.16 0.2 0.2 0.2 4.2e-17 1.4e-21 3.0e-22 6.5e-22
2 Adipose isoform ratio XM_039107861.2 0.05 0.04 6.1e-05 0.04 0.04 0.04 0.04 3.9e-05 3.2e-05 8.1e-05 6.0e-05
3 IC gene expression Tamm41 0.13 0.09 3.3e-04 0.04 0.07 0.07 0.07 9.3e-03 9.7e-04 4.6e-04 8.6e-04
4 BLA gene expression Tamm41 0.1 0.07 1.0e-04 0.04 0.07 0.06 0.06 5.7e-03 1.9e-04 4.8e-04 4.8e-04
5 Brain gene expression Tamm41 0.12 0.07 1.4e-08 0.09 0.09 0.09 0.08 1.2e-08 2.2e-08 2.0e-08 4.8e-08
6 NAcc gene expression Tamm41 0.15 0.09 0.0e+00 0.12 0.11 0.12 0.12 1.8e-18 6.4e-17 7.6e-18 6.3e-18
7 Liver mRNA stability Tamm41 0.04 0.03 5.9e-05 0.04 0.04 0.04 0.04 1.1e-05 4.1e-05 4.8e-05 3.7e-05
8 pVTA gene expression Tamm41 0.12 0.08 3.1e-07 0.1 0.08 0.09 0.09 3.2e-08 2.7e-07 1.1e-07 1.8e-07
9 Brain intron excision ratio chr4_149751358_149754879 0.04 0.03 5.1e-03 0 0.02 0.01 0.01 1.7e-01 1.1e-02 1.9e-02 3.9e-02
10 Adipose mRNA stability Tamm41 0.12 0.07 1.2e-12 0.11 0.11 0.11 0.11 1.3e-12 1.8e-12 4.3e-12 2.1e-12
11 IL gene expression Tamm41 0.21 0.14 2.2e-03 0.09 0.06 0.03 0.06 3.9e-03 1.4e-02 5.9e-02 1.3e-02
12 LHb gene expression Tamm41 0.31 0.16 1.8e-04 0.06 0.06 0.11 0.06 1.3e-02 1.9e-02 1.4e-03 1.3e-02
13 Adipose gene expression Tamm41 0.34 0.14 0.0e+00 0.31 0.34 0.33 0.33 5.5e-35 1.3e-38 1.3e-37 6.5e-38
14 pVTA alternative polyA XM_039107859.2 0.04 0.03 5.2e-03 0.01 0.02 0.01 0.01 4.5e-02 5.9e-03 6.2e-02 2.0e-02
15 Adipose alternative polyA XM_039107860.2 0.38 0.14 0.0e+00 0.38 0.38 0.38 0.38 1.1e-44 1.0e-43 4.3e-44 8.1e-45
16 Adipose intron excision ratio chr4_149751358_149754879 0.02 0.02 8.3e-03 0.02 0.01 0.01 0.01 5.4e-03 1.4e-02 5.3e-02 8.9e-03
17 Adipose isoform ratio XM_039107860.2 0.4 0.14 0.0e+00 0.39 0.38 0.39 0.39 5.7e-46 4.0e-45 1.5e-45 5.7e-46
18 PL gene expression Tamm41 0.03 0.03 2.5e-03 0.03 0.03 0.03 0.03 5.8e-04 5.4e-04 1.3e-04 1.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.40.71.50.50.9-0.7-0.5-1.2-1.2-1.2-1.1-0.5-0.8-0.8-0.7-0.9-0.2-0.6-0.1-0.7-1.2
Area under the delay curve0.10.11.3-1.10.20.10.1-0.10.00.00.30.20.0-0.1-0.3-0.30.3-0.30.2-0.40.2
BMI with tail2.17.116.34.0-3.12.72.42.82.82.82.52.23.03.03.12.71.72.51.12.51.8
BMI without tail0.31.02.11.5-1.10.70.51.11.11.11.00.41.11.11.31.20.21.3-0.01.31.0
Body weight1.35.918.84.3-2.81.91.52.32.32.32.31.32.62.63.02.80.72.90.12.82.0
Weight adjusted by age0.10.10.6-0.80.4-0.0-0.1-0.3-0.2-0.2-0.1-0.1-0.4-0.4-0.5-0.50.1-0.60.1-0.6-0.1
Bone surface0.81.53.10.61.3-1.2-1.0-1.6-1.7-1.8-1.7-0.9-1.2-1.2-1.0-1.2-0.5-0.8-0.3-0.9-1.7
Bone volume0.30.61.30.90.7-0.7-0.6-1.1-1.1-1.1-1.1-0.6-0.6-0.6-0.4-0.6-0.4-0.3-0.3-0.4-1.0
Breakpoint value in progressive ratio session1.61.94.52.1-1.61.20.91.41.41.41.30.81.41.51.51.60.41.70.11.71.3
Number of licking bursts0.30.51.50.30.5-1.2-0.9-0.8-0.9-1.0-1.1-0.9-0.6-0.5-0.1-0.1-0.90.1-0.80.1-0.6
Context. condit. distance diff. score3.03.65.32.3-2.21.71.52.01.91.91.91.32.12.22.32.20.82.10.32.11.9
Locomotion velocity, session 10.10.10.3-0.60.0-0.4-0.2-0.1-0.1-0.2-0.2-0.3-0.1-0.10.10.1-0.40.3-0.50.20.1
Locomotion distance, session 10.50.61.7-0.30.5-1.1-1.1-0.8-0.8-0.8-0.8-1.1-0.6-0.50.1-0.0-1.20.3-1.30.3-0.0
Locomotion velocity, session 20.91.01.6-0.71.1-1.2-1.1-1.3-1.2-1.2-1.2-1.1-1.2-1.2-0.9-0.8-0.9-0.7-0.8-0.7-0.8
Locomotion distance, session 21.11.53.6-0.60.9-1.7-1.7-1.3-1.3-1.3-1.2-1.8-1.0-1.0-0.2-0.2-1.90.2-1.90.2-0.1
Locomotion velocity, session 31.11.33.8-0.41.1-0.7-0.2-1.2-1.3-1.3-1.3-0.1-1.0-0.9-1.3-1.40.3-1.50.6-1.5-2.0
Locomotion distance, session 31.11.22.9-0.21.2-0.9-0.6-1.4-1.4-1.4-1.4-0.5-1.2-1.1-1.2-1.3-0.2-1.20.2-1.2-1.7
Stereotopy head waving bouts, day 30.50.62.0-1.40.5-0.9-1.1-0.5-0.4-0.4-0.4-1.1-0.7-0.7-0.2-0.0-1.20.2-1.20.20.4
Stereotopy head waving duration, day 30.30.41.5-0.80.2-0.7-0.9-0.2-0.2-0.2-0.2-0.9-0.3-0.30.20.3-1.10.4-1.20.40.6
Locomotion velocity, session 71.01.12.7-0.01.1-0.8-0.5-1.3-1.3-1.3-1.3-0.4-0.9-1.0-1.2-1.3-0.1-1.10.3-1.2-1.6
Locomotion distance, session 70.20.30.90.90.20.40.5-0.2-0.2-0.2-0.20.60.0-0.1-0.5-0.60.8-0.70.9-0.7-0.9
Stereotopy head waving bouts, day 71.51.72.6-1.11.5-1.5-1.4-1.6-1.5-1.5-1.5-1.4-1.5-1.5-1.2-1.1-1.2-0.9-0.9-0.9-1.0
Stereotopy head waving duration, day 71.31.62.8-0.71.3-1.6-1.7-1.5-1.4-1.4-1.4-1.7-1.3-1.3-0.8-0.7-1.6-0.4-1.4-0.4-0.6
Locomotion velocity, session 80.50.62.20.9-0.4-0.6-0.7-0.1-0.1-0.1-0.1-0.90.20.20.90.9-1.11.3-1.51.20.8
Locomotion distance, session 81.42.15.32.0-1.50.30.11.00.90.90.9-0.11.31.42.22.0-0.62.3-1.22.31.7
Degree of sensitization distance0.40.40.70.4-0.70.80.60.90.80.80.80.60.70.60.50.50.50.40.30.40.8
Degree of sensitization stereotypy0.40.40.8-0.30.7-0.7-0.6-0.9-0.8-0.8-0.8-0.6-0.7-0.7-0.6-0.6-0.5-0.5-0.3-0.5-0.7
Conditioned locomotion0.40.51.9-0.2-0.30.61.20.30.30.20.21.20.50.6-0.2-0.31.3-0.51.4-0.6-0.8
Cocaine response after cond. corrected2.83.47.3-0.71.7-2.4-2.7-2.0-1.9-2.0-2.0-2.7-1.9-1.9-0.8-0.7-2.6-0.2-2.5-0.2-0.4
Cocaine response after cond. not corrected4.45.18.4-2.02.5-2.7-2.9-2.5-2.5-2.5-2.5-2.8-2.6-2.6-1.8-1.6-2.6-1.1-2.2-1.1-1.1
Cocaine response before conditioning0.81.04.6-2.11.0-0.2-0.0-0.6-0.6-0.6-0.60.1-0.8-0.9-1.4-1.30.4-1.30.8-1.4-1.1
Saline control response3.44.69.8-2.72.3-0.7-0.3-1.8-1.7-1.7-1.7-0.0-2.1-2.1-3.0-3.00.8-3.11.5-3.1-2.8
Bone: connectivity density0.40.61.21.10.7-0.8-0.8-1.0-1.1-1.0-1.0-0.8-0.6-0.7-0.2-0.4-0.6-0.1-0.6-0.1-0.8
Bone: cortical apparent density0.10.10.50.10.3-0.6-0.2-0.5-0.6-0.7-0.7-0.2-0.1-0.2-0.2-0.3-0.1-0.3-0.1-0.2-0.6
Bone: cortical area0.10.10.5-0.20.1-0.7-0.2-0.5-0.5-0.5-0.5-0.2-0.0-0.00.1-0.0-0.30.2-0.30.2-0.4
Bone: cortical porosity0.10.10.3-0.10.2-0.1-0.4-0.2-0.1-0.1-0.1-0.4-0.4-0.4-0.1-0.0-0.4-0.0-0.5-0.00.2
Bone: cortical porosity0.10.10.20.5-0.30.30.00.30.30.30.3-0.00.20.20.40.4-0.10.4-0.30.40.5
Bone: cortical thickness0.10.20.8-0.20.2-0.9-0.4-0.7-0.7-0.6-0.7-0.5-0.2-0.20.0-0.0-0.50.2-0.60.2-0.4
Bone: cortical thickness0.40.51.3-0.60.6-0.40.1-0.8-0.8-0.7-0.80.2-0.3-0.3-0.8-0.90.4-1.00.6-1.0-1.1
Bone: cortical tissue density0.10.10.40.20.2-0.5-0.1-0.4-0.5-0.6-0.6-0.1-0.0-0.1-0.2-0.2-0.1-0.2-0.1-0.2-0.5
Condit. Reinf. active minus inactive responses3.64.06.2-1.92.3-1.6-1.1-2.2-2.2-2.2-2.2-0.9-2.1-2.0-2.5-2.5-0.3-2.40.2-2.4-2.5
Condit. Reinf. active-inactive response ratio4.75.07.1-2.42.6-2.1-1.5-2.5-2.5-2.5-2.5-1.3-2.3-2.4-2.7-2.6-0.8-2.5-0.0-2.5-2.5
Condit. Reinf. active responses1.21.53.4-1.21.3-0.6-0.1-1.2-1.2-1.2-1.20.1-1.1-0.9-1.6-1.70.5-1.70.8-1.8-1.9
Condit. Reinf. inactive responses0.50.61.00.6-0.80.91.00.70.80.80.81.00.81.00.60.50.90.40.60.40.3
Incentive salience index mean2.93.65.0-1.72.2-1.8-1.5-2.2-2.2-2.2-2.2-1.3-2.2-2.0-2.1-2.1-0.8-2.0-0.4-2.0-2.1
Condit. Reinf. lever presses0.71.01.7-0.51.0-1.3-1.3-1.2-1.2-1.1-1.1-1.3-1.3-1.1-0.6-0.6-1.2-0.4-1.0-0.4-0.6
Condit. Reinf. active minus inactive responses1.62.13.3-0.41.6-1.5-1.4-1.8-1.7-1.8-1.7-1.3-1.8-1.7-1.4-1.4-1.0-1.2-0.7-1.2-1.4
Condit. Reinf. active-inactive response ratio0.50.51.10.80.5-0.9-1.0-0.8-0.8-0.9-0.9-1.0-0.8-0.7-0.2-0.1-1.00.0-1.00.0-0.3
Condit. Reinf. active responses1.21.62.4-0.61.5-1.1-0.9-1.6-1.4-1.5-1.5-0.8-1.5-1.5-1.5-1.5-0.4-1.3-0.1-1.3-1.5
Condit. Reinf. inactive responses0.91.12.5-1.31.0-0.00.2-0.7-0.6-0.7-0.70.3-0.9-0.9-1.5-1.50.8-1.61.2-1.6-1.5
Condit. Reinf. lever presses0.30.40.90.20.6-0.7-0.6-0.8-0.8-0.9-0.9-0.6-0.7-0.6-0.5-0.5-0.4-0.5-0.4-0.5-0.8
Condit. Reinf. lever reinforcers received1.72.43.6-0.91.8-1.4-1.3-1.8-1.7-1.8-1.8-1.2-1.9-1.8-1.7-1.7-0.8-1.5-0.4-1.5-1.7
Conditioned reinforcement - actives1.62.75.91.1-1.62.32.41.61.51.51.62.41.41.41.00.72.40.32.40.30.6
Conditioned reinforcement - inactives0.00.00.10.3-0.00.20.0-0.1-0.00.0-0.00.00.0-0.00.20.00.1-0.0-0.0-0.10.0
Conditioned locomotion0.00.00.2-0.50.00.30.20.1-0.0-0.00.20.2-0.2-0.1-0.1-0.10.2-0.20.2-0.20.2
Patch foraging indifference point 0 sec0.10.20.90.1-0.10.40.60.40.40.30.20.60.10.1-0.2-0.20.7-0.50.9-0.4-0.4
Patch foraging indifference point AUC0.60.81.3-0.81.1-0.7-0.8-1.0-1.0-1.0-0.9-0.7-1.0-1.0-1.0-1.0-0.5-1.1-0.2-1.1-0.9
Delay disc. indifference point, 0s delay0.80.93.0-0.6-0.41.11.40.60.60.60.81.50.70.6-0.3-0.41.6-0.71.7-0.7-0.2
Delay disc. indifference point, 16s delay0.00.00.5-0.70.00.10.10.10.00.10.10.1-0.0-0.0-0.2-0.10.1-0.00.0-0.00.1
Delay disc. indifference point, 2s delay0.70.81.7-0.0-0.81.21.20.91.01.01.31.30.80.80.50.31.20.11.00.10.6
Delay disc. indifference point, 24s delay0.70.81.4-1.21.0-1.0-1.1-0.9-0.8-0.8-0.9-1.1-1.0-1.0-0.8-0.6-1.0-0.4-1.0-0.4-0.2
Delay disc. indifference point, 4s delay0.20.21.4-1.2-0.00.40.40.10.20.30.80.40.10.1-0.1-0.20.5-0.30.5-0.30.5
Delay disc. indifference point, 8s delay0.20.30.9-0.90.5-0.5-0.6-0.6-0.5-0.5-0.4-0.5-0.3-0.4-0.6-0.4-0.5-0.4-0.5-0.4-0.1
Indifference point function ln k1.12.03.21.1-1.71.00.81.51.51.51.50.71.41.51.71.80.21.8-0.21.81.8
Indifference point function log k1.12.03.21.1-1.71.00.81.51.51.51.50.71.41.51.71.80.21.8-0.21.81.8
Patch foraging total patch changes 0 sec0.20.30.80.2-0.40.60.80.70.70.60.50.80.40.40.10.10.8-0.10.9-0.1-0.1
Patch foraging total patch changes 12 sec0.50.71.3-1.11.0-0.5-0.5-0.6-0.6-0.6-0.6-0.4-1.0-1.0-1.2-1.0-0.2-1.10.1-1.1-0.8
Patch foraging total patch changes 18 sec0.71.12.7-1.41.2-0.5-0.4-0.8-0.8-0.9-0.8-0.3-1.2-1.3-1.4-1.40.1-1.60.5-1.6-1.2
Patch foraging total patch changes 24 sec0.40.72.70.10.30.60.90.0-0.0-0.1-0.01.10.00.0-0.8-0.91.4-1.21.6-1.2-1.2
Patch foraging total patch changes 6 sec0.30.40.70.8-0.60.90.80.80.70.60.60.80.40.50.40.30.8-0.00.8-0.00.0
Patch foraging time to switch 0 sec0.20.30.70.7-0.60.60.80.60.50.40.40.80.70.60.30.40.80.40.70.40.0
Patch foraging water rate 0 sec0.00.10.30.10.2-0.3-0.5-0.2-0.1-0.1-0.1-0.5-0.1-0.10.10.0-0.50.1-0.50.10.1
Patch foraging water rate 12 sec0.10.21.2-0.4-0.30.2-0.20.40.40.50.6-0.30.10.20.50.5-0.40.4-0.70.51.1
Patch foraging water rate 18 sec0.40.50.90.3-0.80.80.81.00.90.80.90.80.80.80.60.60.70.50.50.50.6
Patch foraging water rate 24 sec0.20.20.8-0.90.1-0.1-0.60.20.10.20.2-0.6-0.2-0.3-0.10.2-0.70.1-0.90.20.9
Patch foraging water rate 6 sec0.20.31.2-0.40.2-0.3-0.90.0-0.1-0.0-0.0-0.9-0.3-0.30.00.2-1.00.2-1.10.20.7
Seeking ratio, delayed vs. immediate footshock1.72.13.01.5-1.71.61.51.61.61.71.31.41.71.71.31.51.11.40.71.41.1
Distance traveled before self-admin1.01.34.3-2.11.2-1.3-1.2-1.2-1.1-1.2-0.9-1.1-1.3-1.3-1.2-0.9-1.0-0.8-0.8-0.8-0.5
Distance traveled after self-admin0.50.61.4-0.70.50.10.5-0.4-0.4-0.4-0.30.6-0.4-0.5-1.1-1.00.9-1.11.2-1.1-1.1
Extensor digitorum longus weight6.525.634.75.0-5.95.34.65.95.75.85.74.35.65.65.55.23.24.72.04.74.7
Bone: elastic displacement0.50.61.7-0.80.30.60.70.10.10.10.10.8-0.2-0.2-0.9-0.91.1-1.11.3-1.1-0.7
Bone: elastic work0.10.20.30.2-0.40.60.50.50.50.50.40.50.50.50.30.20.50.20.40.20.2
Bone: endosteal estimation0.10.20.70.8-0.40.40.70.30.30.20.30.70.50.60.40.20.70.30.60.2-0.2
Bone: endosteal perimeter0.10.30.9-0.60.5-0.30.2-0.5-0.5-0.5-0.50.2-0.3-0.2-0.6-0.70.4-0.60.6-0.6-0.9
Epididymis fat weight0.10.31.01.0-0.50.70.70.50.40.50.20.80.40.50.30.20.80.00.80.1-0.2
Delta time in closed arm before/after self-admin0.40.31.00.5-0.2-0.6-0.50.0-0.0-0.1-0.2-0.60.20.20.70.6-0.81.0-1.01.00.4
Delta time in open arm before/after self-admin0.20.21.6-1.3-0.30.0-0.10.50.50.60.4-0.1-0.1-0.10.10.4-0.30.1-0.40.20.9
Diff in mean of infusions in LGA sessions0.10.10.40.0-0.20.60.50.40.40.50.20.6-0.00.2-0.1-0.00.6-0.30.7-0.20.0
Delay discount exponential model param0.10.11.41.2-0.2-0.0-0.00.20.10.0-0.3-0.00.10.20.40.3-0.10.4-0.10.4-0.2
Extinction: sum of active levers before priming0.20.21.41.2-0.00.30.40.10.10.1-0.10.40.20.1-0.3-0.20.60.00.70.0-0.7
Active lever presses in extinction session 62.52.58.42.9-1.71.41.01.71.71.61.30.81.51.51.81.80.41.90.01.91.3
Bone: final force0.30.51.11.0-0.90.50.70.60.60.60.60.61.01.01.00.80.50.80.30.80.3
Bone: final moment0.30.51.11.0-0.80.60.80.60.60.60.60.81.11.00.90.70.60.70.40.70.1
Food consumed during 24 hour testing period0.00.10.20.20.30.0-0.0-0.2-0.2-0.2-0.20.0-0.2-0.2-0.2-0.30.1-0.20.2-0.3-0.5
Glucose1.52.43.82.0-1.61.81.51.71.81.81.81.41.71.51.51.31.21.21.01.21.2
Heart weight0.30.40.80.3-0.80.50.70.60.60.60.80.60.70.80.90.70.40.70.30.70.6
Delay discount hyperbolic model param0.10.11.01.00.0-0.3-0.3-0.1-0.2-0.2-0.6-0.3-0.1-0.10.20.2-0.40.3-0.30.3-0.4
Intermittent access intake day 1-15 change0.71.42.31.5-1.51.11.21.11.01.21.21.11.41.41.41.30.81.00.51.00.9
Intermittent access intake escalation0.91.82.71.5-1.61.41.41.31.21.41.41.41.61.61.31.41.11.00.81.01.1
Intermittent access intake escalation 22.52.95.02.0-2.11.41.01.81.71.91.90.81.81.81.92.20.21.9-0.31.92.1
Intermitt. access day 1 inactive lever presses0.62.13.3-1.71.7-1.6-1.8-1.5-1.5-1.5-1.4-1.8-1.6-1.6-1.1-1.2-1.5-1.1-1.3-1.1-0.8
Intermitt. access day 15 inactive lever presses0.71.42.5-1.11.2-1.5-1.4-1.5-1.6-1.5-1.2-1.4-1.0-1.1-0.7-0.9-1.2-0.8-1.1-0.8-0.8
Intermitt. access escalation Index0.20.30.5-0.30.6-0.5-0.5-0.7-0.7-0.7-0.6-0.5-0.5-0.6-0.2-0.5-0.3-0.6-0.2-0.6-0.7
Intermittent access day 1 total infusions0.10.20.60.2-0.50.70.80.40.40.40.50.80.40.40.30.20.70.20.70.20.1
Intermittent access day 15 total infusions2.53.77.21.4-2.12.62.72.01.91.92.12.71.81.81.31.22.50.82.40.81.0
Intermittent access terminal intake (last 3 days)3.95.18.31.6-2.62.92.72.52.52.52.72.72.22.21.91.92.31.42.01.51.9
Intermittent access total infusions2.63.16.30.9-1.82.42.51.91.81.81.92.51.51.51.21.02.40.62.30.60.9
Intermittent access day 1 locomotion1.11.41.81.0-1.31.31.31.21.21.11.31.31.21.21.31.01.11.00.91.01.0
Intermittent access day 15 total locomotion2.13.85.31.7-2.32.22.22.02.02.12.22.22.02.01.91.81.81.51.51.51.7
Intermittent access total locomotion2.73.25.61.3-2.02.32.41.81.81.82.02.31.81.81.51.22.11.02.01.01.2
Intermittent access standard deviation0.00.10.30.6-0.00.50.30.30.10.10.10.3-0.1-0.1-0.3-0.10.4-0.30.4-0.3-0.1
Left kidney weight0.42.16.2-0.21.1-1.8-2.4-1.1-1.1-1.1-1.2-2.4-1.4-1.4-0.1-0.1-2.50.4-2.50.40.2
Right kidney weight0.83.67.7-0.51.9-2.3-2.8-1.9-2.0-2.0-1.9-2.8-2.2-2.2-0.9-0.9-2.6-0.5-2.5-0.5-0.6
Cocaine induced anxiety0.30.51.3-0.30.7-0.8-0.4-0.9-1.0-1.0-1.0-0.3-0.5-0.5-0.4-0.7-0.2-0.70.1-0.7-1.2
Post-drug Anxiety2.93.14.6-1.22.0-2.1-2.0-2.0-2.1-2.1-2.1-1.9-1.8-1.8-1.5-1.5-1.6-1.3-1.4-1.3-1.6
Baseline Anxiety1.41.62.6-1.31.6-1.0-1.2-1.1-1.1-1.1-1.2-1.1-1.6-1.6-1.6-1.4-0.7-1.4-0.7-1.3-1.1
Tail length0.20.71.7-0.40.8-1.2-1.3-0.9-0.8-0.8-0.6-1.3-0.8-0.9-0.4-0.3-1.30.0-1.10.0-0.0
Length with tail0.10.42.21.5-0.50.0-0.30.20.30.20.5-0.40.40.20.80.8-0.61.0-0.80.90.8
Length without tail0.51.65.62.4-1.41.61.41.21.21.11.21.31.31.31.11.01.20.70.90.70.4
Times rat made contact with spout0.10.20.50.10.2-0.5-0.6-0.4-0.4-0.3-0.3-0.7-0.3-0.30.10.1-0.70.3-0.70.20.0
Lifetime Intake1.92.34.70.8-1.52.22.11.61.51.51.62.21.31.30.90.82.10.52.00.50.8
Liver weight, left0.10.20.80.6-0.0-0.3-0.6-0.0-0.00.1-0.1-0.7-0.2-0.20.40.4-0.80.5-0.90.50.4
Liver weight, right0.40.72.61.6-0.4-0.5-0.80.0-0.1-0.1-0.1-0.90.30.20.71.0-1.21.2-1.51.20.8
Locomotor activity1.11.82.8-0.81.5-1.6-1.6-1.4-1.4-1.5-1.6-1.6-1.7-1.6-0.8-1.0-1.4-0.6-1.2-0.7-1.1
Locomotor testing distance0.81.52.8-0.51.3-1.4-1.7-1.3-1.3-1.3-1.4-1.6-1.5-1.5-0.6-0.8-1.5-0.4-1.3-0.4-0.8
Locomotor testing rearing2.34.57.5-2.42.5-1.4-1.3-2.1-2.0-2.0-2.0-1.0-2.7-2.6-2.7-2.7-0.3-2.60.4-2.6-2.5
Locomotion in novel chamber0.30.41.51.2-0.3-0.4-0.50.20.20.10.0-0.60.20.10.50.6-0.81.1-0.91.10.4
Locomotion in novel chamber post-restriction0.71.14.90.40.3-1.1-1.6-0.4-0.5-0.6-0.6-1.7-0.5-0.60.40.5-1.90.7-2.20.70.7
Fecal boli incidents, locomotor time 10.30.41.3-1.20.6-0.8-0.9-0.6-0.6-0.5-0.4-0.9-0.7-0.6-0.5-0.3-0.9-0.2-0.8-0.2-0.0
Change in fecal boli incidents, locomotor task0.40.41.40.3-0.20.90.90.20.20.40.21.00.40.4-0.4-0.41.2-0.61.2-0.6-0.6
Time >=10cm from walls, locomotor time 12.62.74.0-1.82.0-1.7-1.7-1.6-1.7-1.6-1.9-1.6-2.0-2.0-1.7-1.6-1.3-1.5-1.0-1.5-1.4
Bouts of movement, locomotor time 10.20.30.80.5-0.30.70.70.50.40.40.40.70.60.60.30.00.8-0.20.9-0.2-0.1
Total resting periods, locomotor time 10.60.71.10.9-0.81.01.00.90.80.90.81.01.01.00.80.51.00.20.90.20.2
Rest time, locomotor task time 14.45.58.73.0-2.82.01.92.52.42.32.31.82.72.72.92.71.12.50.62.52.1
Distance moved, locomotor task time 14.77.011.5-2.83.2-2.3-2.1-2.9-2.8-2.8-2.7-1.9-3.0-3.1-3.4-3.1-1.1-2.9-0.5-2.9-2.6
Vertical activity count, locomotor time 11.22.95.7-2.02.0-1.1-0.9-1.6-1.7-1.6-1.5-0.7-1.8-1.9-2.4-2.2-0.2-2.20.3-2.2-1.9
Time >=10cm from walls, locomotor time 21.01.42.7-1.61.3-1.3-1.2-1.3-1.4-1.2-1.2-1.2-1.4-1.3-1.0-1.0-1.0-1.0-1.1-1.0-0.7
Bouts of movement, locomotor time 20.30.40.7-0.30.7-0.7-0.9-0.7-0.7-0.7-0.9-0.8-0.6-0.7-0.5-0.5-0.7-0.3-0.7-0.3-0.5
Total resting periods, locomotor time 20.30.61.1-0.10.8-0.9-1.0-0.7-0.8-0.8-1.1-1.0-0.7-0.8-0.5-0.5-0.9-0.3-0.7-0.4-0.7
Rest time, locomotor task time 21.01.24.32.1-1.30.80.91.01.00.90.70.81.41.31.31.20.61.20.31.20.4
Distance moved, locomotor task time 21.72.03.3-1.81.7-1.2-1.1-1.5-1.5-1.5-1.2-1.0-1.7-1.7-1.8-1.6-0.6-1.7-0.2-1.6-1.1
Vertical activity count, locomotor time 20.10.10.4-0.30.3-0.4-0.6-0.2-0.3-0.2-0.1-0.6-0.3-0.4-0.0-0.0-0.70.1-0.60.10.3
Light reinforcement 10.30.82.6-1.61.0-0.7-1.0-0.7-0.7-0.7-0.6-0.9-1.1-1.0-1.0-0.8-0.8-0.8-0.7-0.8-0.3
Light reinforcement 20.10.10.40.20.10.40.40.10.0-0.0-0.10.5-0.0-0.2-0.4-0.40.6-0.60.6-0.6-0.5
Bone: marrow area0.10.20.60.8-0.40.40.60.20.20.10.20.60.50.50.30.10.60.20.60.2-0.3
Bone: maximum diameter0.30.61.4-1.10.8-1.2-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.7-0.5-0.5-0.8-0.2-0.7-0.2-0.5
Bone: maximum force0.61.01.91.3-1.20.81.10.90.90.80.81.01.41.41.20.90.81.00.60.90.3
Bone: maximum moment0.50.91.81.3-1.10.81.10.80.80.70.71.11.41.31.10.80.90.80.70.80.1
Mean time between licks in bursts0.10.21.01.0-0.40.2-0.00.30.30.30.3-0.10.50.30.70.6-0.20.6-0.30.70.5
Mean num. licks in bursts0.10.10.4-0.5-0.10.60.20.30.40.60.60.20.10.0-0.1-0.00.3-0.10.2-0.10.4
Cd content in liver0.20.20.5-0.0-0.4-0.1-0.10.20.10.20.2-0.20.40.40.60.6-0.40.7-0.50.70.7
Co content in liver0.70.82.51.6-1.10.50.60.80.70.70.60.51.01.01.11.10.21.1-0.21.10.7
Cu content in liver0.70.82.11.5-0.91.21.10.90.80.90.91.20.90.90.70.51.10.31.00.30.2
Fe content in liver2.12.53.81.6-1.72.01.61.91.81.91.91.51.71.71.61.41.31.31.01.31.3
K content in liver1.21.22.9-1.20.9-1.4-1.6-1.0-0.9-0.9-0.9-1.7-1.2-1.1-0.4-0.3-1.70.2-1.60.10.2
Mg content in liver0.20.20.9-1.00.5-0.4-0.4-0.4-0.3-0.3-0.3-0.4-0.6-0.5-0.5-0.4-0.3-0.4-0.2-0.4-0.2
Mn content in liver0.30.30.50.10.6-0.6-0.6-0.6-0.6-0.7-0.7-0.6-0.7-0.6-0.5-0.5-0.5-0.4-0.3-0.4-0.6
Na content in liver0.70.82.3-1.51.0-0.7-0.6-0.9-0.9-0.8-0.8-0.5-1.0-1.0-1.0-1.1-0.3-0.90.0-0.9-0.9
Rb content in liver0.20.20.5-0.20.6-0.2-0.3-0.6-0.3-0.4-0.4-0.2-0.6-0.6-0.7-0.6-0.0-0.60.1-0.6-0.5
Se content in liver1.41.73.61.9-1.51.31.31.31.31.31.31.21.51.51.41.21.01.20.71.10.8
Sr content in liver0.70.61.5-0.50.6-1.2-1.1-0.7-0.9-0.9-0.9-1.1-0.6-0.6-0.2-0.2-1.20.1-1.00.0-0.3
Zn content in liver0.20.20.60.3-0.1-0.3-0.4-0.1-0.1-0.00.0-0.5-0.10.00.40.5-0.70.7-0.80.70.5
Bone: minimum diameter0.71.32.40.9-1.31.01.51.11.11.11.11.41.51.61.21.01.21.01.00.90.5
Time in familiar zone, hab. session 10.20.20.50.70.3-0.4-0.4-0.6-0.5-0.5-0.5-0.4-0.2-0.3-0.2-0.2-0.3-0.1-0.4-0.2-0.5
Time in novel zone, hab. session 10.10.10.5-0.7-0.20.20.20.40.30.20.20.20.20.20.10.10.10.10.20.10.4
Total zone transitions, hab. session 10.70.91.5-1.01.1-0.9-0.8-1.1-1.2-1.2-1.2-0.7-1.0-1.0-1.0-1.1-0.4-0.9-0.3-1.0-1.0
Total locomotion distance, hab. session 10.10.10.3-0.20.3-0.10.1-0.3-0.5-0.4-0.40.1-0.2-0.2-0.4-0.50.2-0.50.2-0.5-0.5
Locomotion velocity, hab. session 10.10.10.3-0.60.4-0.3-0.1-0.4-0.5-0.4-0.4-0.1-0.4-0.3-0.4-0.4-0.0-0.4-0.0-0.4-0.4
Time in familiar zone, hab. session 20.10.10.20.2-0.2-0.1-0.10.10.20.30.3-0.10.10.10.30.3-0.20.4-0.30.40.4
Time in novel zone, hab. session 20.10.10.2-0.20.3-0.2-0.1-0.3-0.4-0.5-0.5-0.0-0.3-0.3-0.4-0.40.1-0.40.1-0.4-0.4
Total zone transitions, hab. session 21.21.62.7-0.31.2-1.7-1.6-1.5-1.6-1.5-1.5-1.6-1.2-1.2-0.6-0.7-1.5-0.3-1.5-0.3-0.7
Total locomotion distance, hab. session 21.52.03.4-0.61.5-1.8-1.7-1.7-1.8-1.8-1.8-1.7-1.5-1.5-0.9-1.0-1.5-0.6-1.4-0.6-0.9
Locomotion velocity, hab. session 21.31.82.8-0.71.4-1.6-1.6-1.6-1.7-1.6-1.6-1.6-1.5-1.4-1.0-1.0-1.4-0.7-1.3-0.7-0.9
Novel to familiar place preference ratio0.00.00.3-0.5-0.10.20.10.30.20.20.20.10.10.10.00.10.1-0.00.1-0.00.3
Novelty place preference0.10.10.5-0.2-0.40.30.10.50.40.40.40.10.30.30.40.4-0.00.4-0.10.40.7
Time in novel zone, NPP test0.20.20.4-0.3-0.50.50.40.60.60.50.50.40.50.50.40.40.30.30.20.30.7
Total zone transitions, NPP test0.60.92.9-0.30.7-1.3-1.4-0.9-1.0-1.0-1.0-1.4-0.9-0.8-0.1-0.1-1.50.3-1.70.30.1
Total locomotion distance, NPP test0.10.20.70.10.0-0.3-0.5-0.0-0.2-0.1-0.1-0.6-0.2-0.10.30.3-0.70.5-0.80.50.5
Locomotion velocity, NPP test0.30.41.6-0.00.2-0.7-0.9-0.3-0.4-0.4-0.4-1.0-0.5-0.40.20.3-1.10.5-1.30.50.5
Intraocular pressure0.00.00.10.1-0.00.3-0.10.20.20.30.4-0.1-0.1-0.1-0.30.1-0.1-0.1-0.2-0.10.4
Delta distance traveled before/after self-admin2.52.69.90.5-0.92.02.61.21.11.11.02.71.01.0-0.1-0.43.0-0.93.1-0.9-0.8
Delta ambulatory time before/after self-admin1.21.55.10.7-0.81.61.91.00.90.90.82.00.90.80.3-0.12.2-0.52.3-0.5-0.5
Parametrial fat weight0.00.10.20.20.2-0.3-0.4-0.3-0.3-0.4-0.2-0.4-0.4-0.4-0.1-0.1-0.4-0.1-0.4-0.1-0.0
Pavlov. Cond. lever latency0.30.41.00.6-0.60.0-0.10.30.50.50.4-0.20.70.60.80.9-0.41.0-0.71.00.8
Pavlov. Cond. magazine entry latency1.21.62.8-0.21.3-1.5-1.7-1.4-1.5-1.5-1.5-1.7-1.6-1.4-0.7-0.7-1.5-0.5-1.4-0.5-0.7
Pavlov. Cond. change in total contacts0.20.20.50.10.5-0.2-0.3-0.5-0.5-0.5-0.5-0.2-0.7-0.5-0.4-0.5-0.1-0.50.1-0.5-0.6
Pavlov. Cond. index score0.30.40.9-0.10.7-0.5-0.6-0.6-0.8-0.8-0.7-0.5-1.0-0.8-0.6-0.7-0.3-0.7-0.1-0.7-0.7
Pavlov. Cond. latency score0.30.41.0-0.30.7-0.6-0.6-0.6-0.7-0.7-0.7-0.6-1.0-0.9-0.6-0.6-0.4-0.6-0.2-0.6-0.6
Pavlov. Cond. lever contacts0.20.20.50.00.3-0.00.1-0.3-0.4-0.4-0.40.2-0.5-0.3-0.4-0.50.4-0.60.6-0.6-0.7
Pavlov. Cond. magazine entry number0.81.01.70.3-1.11.11.21.11.21.21.21.21.31.20.70.81.00.60.80.60.8
Pavlov. Cond. intertrial magazine entries0.40.41.80.2-0.10.61.00.20.1-0.0-0.01.00.40.3-0.3-0.51.2-0.61.3-0.6-0.9
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-0.10.8-0.6-0.7-0.8-0.9-0.9-0.9-0.6-1.0-0.8-0.6-0.7-0.4-0.7-0.2-0.7-0.7
Pavlov. Cond. response bias0.81.01.7-0.21.1-1.1-1.1-1.1-1.2-1.2-1.2-1.1-1.3-1.1-0.7-0.8-0.9-0.7-0.6-0.7-0.8
Pavlov. Cond. lever latency0.00.10.10.1-0.20.40.30.20.20.20.30.30.30.20.10.10.40.00.40.00.2
Pavlov. Cond. magazine entry latency0.20.30.90.40.3-0.6-0.8-0.4-0.5-0.5-0.5-0.8-0.4-0.4-0.00.1-0.90.2-1.00.20.0
Pavlov. Cond. change in total contacts0.81.33.0-0.21.0-1.4-1.7-1.2-1.1-1.1-1.2-1.7-1.2-1.2-0.4-0.3-1.7-0.0-1.7-0.0-0.2
Pavlov. Cond. index score0.20.30.60.40.4-0.7-0.7-0.6-0.6-0.6-0.6-0.8-0.5-0.4-0.1-0.1-0.7-0.0-0.8-0.0-0.3
Pavlov. Cond. latency score0.30.41.10.40.3-0.8-0.9-0.6-0.6-0.6-0.6-0.9-0.5-0.40.00.1-1.00.2-1.10.2-0.1
Pavlov. Cond. lever contacts0.10.10.30.00.3-0.5-0.5-0.4-0.4-0.4-0.4-0.5-0.5-0.4-0.2-0.2-0.5-0.1-0.5-0.1-0.3
Pavlov. Cond. magazine entry number0.91.12.5-0.5-0.81.31.51.11.11.11.21.60.91.00.30.21.50.01.60.00.4
Pavlov. Cond. intertrial magazine entries0.40.61.3-0.80.6-0.30.2-0.7-0.7-0.7-0.60.3-0.5-0.4-0.9-1.00.6-1.00.8-1.0-1.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.40.5-0.8-0.8-0.7-0.7-0.7-0.8-0.9-0.6-0.6-0.2-0.2-0.8-0.1-0.9-0.1-0.4
Pavlov. Cond. response bias0.20.20.50.30.4-0.6-0.7-0.5-0.5-0.5-0.6-0.7-0.5-0.5-0.2-0.2-0.6-0.1-0.7-0.1-0.3
Time in closed arm before self-admin0.10.22.01.4-0.40.50.40.20.20.30.20.40.20.20.30.20.4-0.10.3-0.0-0.2
Time in closed arm after self-admin0.70.81.91.2-0.90.20.10.50.50.50.7-0.00.80.81.41.2-0.41.4-0.71.31.0
Time in open arm before self-admin0.00.00.10.0-0.20.20.10.10.10.10.20.10.20.30.20.20.10.30.00.30.4
Time in open arm after self-admin0.10.10.8-0.9-0.10.20.20.20.20.20.10.2-0.1-0.0-0.3-0.00.2-0.30.3-0.30.3
Bone: periosteal estimation0.00.10.20.3-0.1-0.20.3-0.2-0.2-0.3-0.30.30.30.30.2-0.00.30.20.30.1-0.5
Bone: periosteal perimeter0.61.12.3-1.11.1-1.2-0.5-1.3-1.3-1.4-1.4-0.4-0.9-0.9-1.1-1.2-0.2-0.90.1-1.0-1.5
Bone: post-yield work0.10.20.50.50.1-0.7-0.3-0.5-0.5-0.6-0.5-0.30.10.10.20.1-0.40.3-0.50.2-0.4
Progressive ratio test 1 active lever presses0.60.73.4-0.6-0.11.11.20.30.40.30.41.3-0.0-0.0-0.4-0.61.6-0.71.9-0.7-0.4
Progressive ratio test 1 breakpoint0.50.73.1-0.5-0.11.11.20.40.40.30.41.3-0.0-0.0-0.3-0.61.5-0.71.7-0.7-0.4
Progressive ratio test 1 inactive lever presses0.00.00.1-0.20.2-0.1-0.1-0.3-0.3-0.4-0.3-0.1-0.1-0.20.1-0.30.0-0.30.0-0.3-0.3
Progressive ratio test 2 active lever presses2.83.36.51.0-1.92.52.42.02.02.02.12.41.61.61.21.12.30.82.10.81.2
Progressive ratio test 2 breakpoint3.03.56.71.1-2.02.62.52.12.02.02.22.41.71.71.31.22.30.92.10.91.3
Progressive ratio test 2 inactive lever presses0.60.92.41.5-1.11.21.20.70.70.70.71.21.11.01.20.71.10.60.90.60.2
Incentive Sensitization - Responses2.33.34.81.7-2.12.22.12.01.91.92.02.01.91.91.71.61.71.31.41.31.4
Incentive Sensitization - Breakpoint2.93.85.41.8-2.32.32.22.12.02.12.22.12.12.11.91.81.81.51.41.51.6
Sum of active levers in priming session hrs 5-60.20.20.90.9-0.40.30.50.30.30.20.10.40.40.40.20.30.40.40.30.4-0.2
Progressive ratio0.30.51.00.8-0.90.40.40.70.70.60.70.30.70.70.91.00.00.9-0.20.90.9
Food seeking constrained by brief footshock1.51.93.21.8-1.41.61.81.41.31.31.21.81.61.51.30.81.70.71.50.70.3
Seeking ratio, punishment vs. effort0.20.20.90.4-0.20.70.70.30.40.40.30.70.40.40.1-0.20.9-0.20.9-0.2-0.3
Retroperitoneal fat weight0.00.21.91.4-0.10.00.2-0.4-0.4-0.4-0.40.30.10.10.2-0.10.3-0.20.4-0.2-0.7
Reaction time number correct0.30.61.10.4-0.81.01.00.80.81.00.91.00.80.80.60.40.90.40.80.40.4
Reaction time mean minus median0.20.51.5-0.80.60.10.2-0.2-0.4-0.4-0.20.3-0.5-0.6-1.0-0.90.6-1.20.9-1.2-0.7
Reaction time mean minus median AUC0.20.51.5-1.00.60.20.2-0.1-0.3-0.3-0.20.3-0.6-0.6-1.0-0.90.6-1.20.9-1.2-0.7
Reaction time num false alarms1.92.75.81.9-1.70.70.21.61.71.71.40.01.51.42.22.2-0.62.4-1.02.42.1
Reaction time num false alarms AUC1.21.94.71.7-1.30.2-0.21.11.21.10.9-0.41.11.01.91.9-1.02.2-1.32.21.7
Reaction time trials correct on left0.30.61.10.4-0.81.01.00.80.81.00.91.00.80.80.60.40.90.40.80.40.4
Reaction time trials on left0.30.50.90.3-0.70.90.90.70.70.90.80.90.70.70.50.40.80.40.70.40.4
Reaction time mean1.32.15.2-1.71.4-0.5-0.1-1.1-1.3-1.3-1.10.1-1.3-1.3-2.2-1.90.6-2.31.1-2.2-1.7
Reaction time mean AUC1.21.95.0-1.61.4-0.4-0.1-1.1-1.3-1.2-1.00.0-1.2-1.3-2.1-1.80.5-2.21.0-2.2-1.6
Median of all reaction times1.31.94.9-1.61.4-0.4-0.1-1.1-1.3-1.3-1.00.1-1.2-1.2-2.1-1.80.6-2.21.0-2.2-1.6
Reaction time omissions1.52.24.0-2.01.5-1.6-1.9-1.4-1.5-1.5-1.2-1.9-1.7-1.7-1.4-0.9-1.7-0.8-1.5-0.7-0.1
Reaction time false alarm rate0.70.92.40.9-0.6-0.6-0.80.40.40.30.2-0.90.40.31.11.3-1.31.5-1.51.51.1
Reaction time premature initiation rate0.30.43.8-1.90.6-0.7-0.4-0.5-0.4-0.4-0.5-0.4-0.5-0.5-0.6-0.5-0.4-0.5-0.2-0.5-0.3
Reaction time premature initiations0.20.34.1-2.00.5-0.4-0.2-0.3-0.2-0.1-0.2-0.1-0.3-0.4-0.5-0.5-0.1-0.50.1-0.5-0.1
Std. dev. reaction times0.50.91.8-1.21.1-0.7-0.8-0.9-1.0-1.0-0.8-0.7-1.0-1.1-1.3-1.1-0.4-1.2-0.1-1.2-0.7
Reaction time trials completed0.30.50.90.3-0.70.90.90.70.70.90.80.90.70.70.50.40.80.40.70.40.4
Reaction time trials AUC0.30.61.00.5-0.81.00.90.80.81.00.90.90.70.80.60.50.80.50.70.50.5
Run reversals in cocaine runway, females1.11.13.1-0.80.9-1.2-1.7-0.6-0.6-0.7-0.8-1.7-1.2-1.2-0.5-0.3-1.8-0.1-1.8-0.00.3
Run reversals in cocaine runway, males0.80.82.80.50.4-1.1-1.3-0.5-0.5-0.5-0.7-1.4-0.3-0.50.40.3-1.60.6-1.70.60.3
Latency to leave start box in cocaine runway2.42.74.8-2.22.0-1.7-1.5-1.7-1.7-1.7-1.7-1.4-1.9-1.9-1.8-1.7-1.1-1.5-0.6-1.5-1.4
Latency to leave start box in cocaine runway, F1.01.15.3-2.31.2-1.0-0.8-0.8-0.9-0.9-0.8-0.8-1.3-1.3-1.3-1.1-0.6-0.9-0.2-0.9-0.6
Latency to leave start box in cocaine runway, M1.91.83.1-0.71.6-1.0-0.9-1.5-1.5-1.5-1.6-0.7-1.3-1.3-1.4-1.6-0.3-1.70.1-1.7-1.8
Std. dev. time between licks in bursts0.50.61.90.7-0.2-0.6-1.0-0.1-0.1-0.1-0.1-1.1-0.1-0.10.70.8-1.41.0-1.41.01.0
Total sessions with >9 infusions0.50.52.2-0.90.20.70.8-0.10.0-0.10.11.0-0.2-0.2-0.8-0.71.2-0.91.5-0.9-0.6
Short access day 1 total inactive lever presses1.52.03.2-1.31.7-1.0-0.9-1.5-1.6-1.5-1.5-0.7-1.5-1.5-1.7-1.8-0.3-1.80.1-1.8-1.7
Short access day 10 total inactive lever presses1.53.76.7-1.42.0-2.6-2.6-2.0-2.1-2.0-2.1-2.6-1.8-1.8-0.9-1.1-2.4-1.1-2.3-1.1-1.1
Short access day 1 total infusions0.40.51.3-0.90.50.50.4-0.3-0.2-0.3-0.10.5-0.5-0.5-0.9-0.90.9-1.01.1-1.0-0.6
Short access day 10 total infusions1.72.23.90.8-1.62.02.01.61.61.61.72.01.41.41.11.01.80.81.70.81.0
Short access total infusions0.50.62.5-0.2-0.41.21.20.50.50.40.51.30.30.3-0.2-0.21.4-0.41.6-0.4-0.1
Short access day 1 locomotion1.51.94.10.4-1.42.01.71.51.61.51.81.71.31.20.80.91.60.61.50.61.3
Short access day 10 total locomotion0.00.00.1-0.20.00.20.20.10.10.10.20.2-0.1-0.10.1-0.10.2-0.10.3-0.10.2
Short access total locomotion0.70.83.5-0.90.20.81.0-0.1-0.1-0.10.01.2-0.3-0.3-0.9-1.01.5-1.11.9-1.1-0.9
One hour access (0.3 mA shock)5.15.911.32.0-2.63.43.32.62.52.52.63.32.22.31.41.53.10.92.90.91.3
Compulsive drug intake0.70.82.2-0.70.9-0.6-0.1-1.2-1.2-1.1-1.00.0-0.6-0.5-0.9-1.10.4-1.20.6-1.2-1.5
One hour access (shock baseline)3.35.19.41.8-2.53.12.72.72.72.72.62.72.01.91.51.72.41.22.21.31.7
Social response proportion2.22.58.6-2.91.8-1.2-1.0-1.4-1.5-1.4-1.2-0.9-1.8-1.6-2.1-1.9-0.5-1.70.0-1.7-1.3
Social responses1.21.62.9-1.51.4-1.5-1.7-1.2-1.3-1.1-1.2-1.7-1.4-1.4-1.0-0.8-1.6-0.4-1.3-0.4-0.4
Social time0.40.51.0-0.60.7-1.0-0.7-0.8-1.0-0.9-0.8-0.7-0.7-0.7-0.6-0.5-0.7-0.4-0.5-0.4-0.6
Soleus weight1.33.75.41.9-2.22.32.12.32.22.22.22.01.92.11.81.71.71.41.31.41.5
Bone: stiffness0.40.61.51.2-0.90.30.40.60.60.60.60.31.01.01.21.00.11.1-0.11.10.5
Tibialis anterior weight0.61.96.70.3-0.71.92.11.11.01.11.12.20.90.9-0.1-0.32.4-0.72.6-0.7-0.6
Time to tail flick, vehicle, before self-admin1.21.21.8-1.31.3-0.9-0.9-1.3-1.3-1.3-1.1-0.8-1.3-1.2-1.1-1.3-0.5-1.1-0.3-1.1-0.9
Time to tail flick, vehicle, after self-admin1.21.54.10.9-0.90.1-0.60.70.80.81.0-0.80.80.81.51.7-1.31.8-1.71.92.0
Time to tail flick, test, before self-admin0.10.10.60.8-0.30.20.40.0-0.0-0.0-0.10.40.30.30.00.10.40.10.30.1-0.3
Time to tail flick, test, after self-admin0.10.10.4-0.20.1-0.1-0.5-0.10.00.00.1-0.5-0.4-0.50.20.2-0.60.1-0.70.10.6
Delta time to tail flick, vehicle, before/after SA0.50.52.00.7-0.1-0.6-0.9-0.00.0-0.1-0.1-1.00.20.10.50.7-1.20.8-1.40.80.6
Delta time to tail flick, test, before/after SA0.30.40.8-0.50.7-0.5-0.9-0.5-0.4-0.4-0.4-0.9-0.7-0.8-0.4-0.4-0.8-0.4-0.8-0.40.1
Tibia length0.82.33.3-0.71.8-1.5-1.4-1.8-1.8-1.8-1.8-1.3-1.8-1.8-1.5-1.6-0.9-1.4-0.4-1.4-1.7
Ambulatory time before self-admin0.60.83.1-1.80.9-1.0-1.2-0.8-0.8-0.8-0.5-1.2-0.9-1.0-0.9-0.5-1.2-0.3-1.0-0.30.2
Ambulatory time after self-admin0.30.41.7-0.6-0.10.60.90.30.30.30.41.00.00.1-0.4-0.41.1-0.61.3-0.6-0.4
Bone: tissue strength0.60.61.4-0.40.9-0.7-0.5-0.9-0.9-0.9-1.0-0.5-0.8-0.8-0.9-1.0-0.2-0.8-0.0-0.9-1.2
Total heroin consumption0.20.32.31.5-0.50.30.20.50.50.50.00.20.40.50.30.50.10.5-0.10.5-0.0
Bone: trabecular number1.01.73.7-0.41.5-1.0-0.8-1.7-1.7-1.7-1.7-0.7-1.3-1.4-1.4-1.6-0.2-1.30.1-1.4-1.9
Bone: trabecular spacing0.70.91.9-0.5-0.91.00.81.31.31.41.30.80.80.80.60.80.60.70.40.71.4
Bone: trabecular thickness0.70.83.21.30.6-0.50.1-1.1-1.2-1.2-1.20.2-0.2-0.2-0.6-0.90.4-1.00.5-1.0-1.8
Bone: trabecular tissue density2.53.77.5-2.72.0-0.9-0.1-1.7-1.7-1.7-1.60.1-1.6-1.6-2.5-2.60.7-2.71.4-2.7-2.7
Water consumed over 24 hours0.10.10.30.6-0.40.10.10.30.30.30.3-0.00.20.30.60.5-0.10.5-0.20.50.3
Number of responses in last shaping day2.22.44.61.4-1.72.11.81.71.81.71.91.81.41.51.21.11.71.01.41.01.2