Hub : Genes

Syt5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Syt5 0.23 0.14 0.0e+00 0.2 0.23 0.22 0.22 2.3e-21 2.5e-24 3.6e-24 8.5e-24
2 IC mRNA stability Syt5 0.22 0.17 1.7e-05 0.04 0.05 0.04 0.04 6.5e-03 2.9e-03 5.5e-03 6.0e-03
3 BLA mRNA stability Syt5 0.22 0.13 1.4e-09 0.1 0.12 0.11 0.11 4.8e-06 1.0e-06 1.3e-06 2.2e-06
4 IL mRNA stability Syt5 0.28 0.16 1.2e-05 0.22 0.19 0.22 0.2 6.6e-06 2.8e-05 4.9e-06 1.4e-05
5 OFC mRNA stability Syt5 0.31 0.17 6.6e-05 0.2 0.06 0.09 0.12 2.1e-05 1.3e-02 3.8e-03 1.1e-03
6 NAcc mRNA stability Syt5 0.4 0.23 0.0e+00 0.32 0.33 0.33 0.31 3.1e-49 8.1e-51 2.0e-51 1.5e-48
7 OFC gene expression Syt5 0.64 0.17 1.0e-11 0.13 0.22 0.2 0.21 6.2e-04 7.5e-06 1.9e-05 1.1e-05
8 pVTA mRNA stability Syt5 0.14 0.08 2.1e-07 0.03 0.05 0.04 0.04 1.6e-03 1.1e-04 1.5e-04 1.7e-04
9 LHb mRNA stability Syt5 0.38 0.17 7.8e-08 0.29 0.29 0.28 0.3 1.3e-07 1.4e-07 2.5e-07 8.2e-08
10 Brain mRNA stability Syt5 0.22 0.12 0.0e+00 0.22 0.26 0.25 0.26 6.7e-20 2.3e-24 1.9e-23 1.4e-24
11 IL gene expression Syt5 0.63 0.16 1.8e-15 0.32 0.42 0.41 0.43 2.4e-08 1.9e-11 4.8e-11 1.6e-11
12 RMTg gene expression Syt5 0.13 0.09 2.9e-03 0.07 0.09 0.06 0.1 5.7e-03 2.2e-03 1.2e-02 1.2e-03
13 PL gene expression Syt5 0.47 0.17 0.0e+00 0.42 0.42 0.42 0.41 9.6e-50 3.5e-49 1.7e-49 1.2e-48
14 BLA gene expression Syt5 0.52 0.18 0.0e+00 0.32 0.31 0.32 0.32 1.0e-17 5.1e-17 3.1e-17 1.4e-17
15 Brain gene expression Syt5 0.48 0.18 0.0e+00 0.38 0.41 0.42 0.43 4.1e-37 9.3e-41 8.8e-42 2.5e-43
16 LHb gene expression Syt5 0.61 0.25 1.1e-10 0.33 0.3 0.37 0.34 1.1e-08 7.7e-08 1.0e-09 8.3e-09
17 NAcc gene expression Syt5 0.37 0.13 0.0e+00 0.36 0.36 0.37 0.37 2.2e-56 3.9e-58 2.4e-59 1.7e-58
18 IC gene expression Syt5 0.55 0.15 0.0e+00 0.36 0.36 0.35 0.36 6.3e-16 4.4e-16 1.6e-15 9.6e-16
19 pVTA gene expression Syt5 0.43 0.16 0.0e+00 0.16 0.22 0.19 0.18 6.7e-13 1.2e-17 2.8e-15 8.5e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.20.3-0.3-0.4-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4
Area under the delay curve0.30.40.70.60.60.60.80.70.70.60.60.70.70.60.60.60.60.60.50.60.50.4
BMI with tail0.62.12.31.41.41.41.51.51.51.41.41.51.51.51.51.41.51.51.51.41.41.3
BMI without tail0.00.10.4-0.3-0.3-0.3-0.6-0.6-0.2-0.1-0.1-0.4-0.4-0.2-0.0-0.1-0.1-0.1-0.20.00.20.3
Body weight0.73.25.4-2.2-2.2-2.2-2.3-2.1-1.9-1.9-1.9-1.9-1.9-1.7-1.6-1.8-1.5-1.5-1.4-1.3-1.0-1.0
Weight adjusted by age0.81.21.9-1.0-1.0-1.0-0.7-0.8-1.1-1.1-1.1-0.9-1.0-1.1-1.2-1.3-1.2-1.2-0.9-1.4-1.3-1.3
Bone surface2.54.66.4-2.4-2.4-2.4-2.5-2.3-2.3-2.2-2.2-2.3-2.3-2.2-2.1-2.1-2.1-2.1-1.8-1.9-1.6-1.5
Bone volume2.13.84.9-2.1-2.1-2.1-2.2-2.2-2.0-2.0-2.0-2.1-2.1-2.0-1.9-1.9-1.9-1.9-1.7-1.7-1.5-1.4
Breakpoint value in progressive ratio session0.40.40.70.70.70.70.50.80.60.60.60.80.80.70.60.60.70.70.80.50.50.5
Number of licking bursts0.00.10.10.30.30.30.20.10.30.30.20.20.20.20.20.20.20.20.20.20.20.2
Context. condit. distance diff. score0.00.00.10.20.20.20.30.40.10.10.10.30.20.1-0.0-0.0-0.0-0.00.3-0.2-0.2-0.2
Locomotion velocity, session 10.80.83.2-0.2-0.2-0.20.4-0.1-0.5-0.7-0.7-0.3-0.4-0.7-1.0-1.0-1.0-1.1-1.2-1.3-1.7-1.8
Locomotion distance, session 13.44.35.9-1.8-1.8-1.8-1.6-1.6-2.0-2.1-2.1-1.9-1.9-2.1-2.2-2.2-2.2-2.2-2.3-2.3-2.4-2.4
Locomotion velocity, session 20.10.10.70.10.10.10.40.2-0.0-0.1-0.10.10.0-0.1-0.3-0.3-0.3-0.3-0.3-0.5-0.8-0.8
Locomotion distance, session 22.43.34.5-1.7-1.7-1.7-1.5-1.8-1.8-1.8-1.8-1.8-1.9-1.8-1.9-1.9-1.9-1.9-2.1-1.9-1.9-1.9
Locomotion velocity, session 30.00.00.00.20.20.20.20.20.10.10.10.10.10.1-0.0-0.0-0.0-0.00.1-0.1-0.1-0.2
Locomotion distance, session 30.40.40.9-0.5-0.5-0.5-0.4-0.3-0.6-0.6-0.7-0.5-0.5-0.6-0.7-0.7-0.7-0.7-0.6-0.8-0.9-0.9
Stereotopy head waving bouts, day 30.10.20.20.40.40.40.20.40.40.40.40.40.40.40.50.50.50.40.20.40.40.4
Stereotopy head waving duration, day 30.20.20.30.40.40.40.20.30.40.40.40.40.40.50.50.50.50.50.40.50.50.5
Locomotion velocity, session 70.20.20.4-0.2-0.2-0.2-0.2-0.1-0.4-0.4-0.4-0.2-0.3-0.4-0.5-0.5-0.5-0.5-0.4-0.6-0.6-0.6
Locomotion distance, session 70.10.20.6-0.2-0.2-0.20.20.1-0.3-0.3-0.3-0.1-0.2-0.4-0.5-0.5-0.5-0.5-0.3-0.7-0.7-0.8
Stereotopy head waving bouts, day 70.10.10.6-0.3-0.3-0.3-0.7-0.5-0.3-0.2-0.2-0.3-0.4-0.2-0.1-0.1-0.1-0.1-0.3-0.00.10.1
Stereotopy head waving duration, day 70.10.10.4-0.4-0.4-0.4-0.7-0.5-0.3-0.2-0.2-0.3-0.4-0.2-0.1-0.1-0.1-0.1-0.2-0.00.00.1
Locomotion velocity, session 80.20.20.7-0.0-0.0-0.0-0.1-0.1-0.3-0.3-0.3-0.2-0.3-0.3-0.5-0.5-0.5-0.5-0.5-0.7-0.8-0.9
Locomotion distance, session 80.40.61.2-0.5-0.5-0.5-0.4-0.4-0.7-0.7-0.7-0.6-0.6-0.8-0.9-0.9-0.9-0.9-0.8-1.0-1.1-1.1
Degree of sensitization distance0.00.00.0-0.0-0.0-0.0-0.0-0.1-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.2-0.1-0.1
Degree of sensitization stereotypy0.00.00.2-0.1-0.1-0.1-0.4-0.2-0.00.00.0-0.1-0.10.10.10.10.10.20.00.20.30.3
Conditioned locomotion0.10.20.5-0.3-0.2-0.2-0.10.1-0.3-0.4-0.4-0.1-0.1-0.3-0.5-0.5-0.4-0.5-0.0-0.6-0.7-0.7
Cocaine response after cond. corrected2.63.14.31.61.51.61.41.31.71.81.81.51.51.81.91.91.91.92.02.02.12.1
Cocaine response after cond. not corrected0.10.10.4-0.0-0.1-0.1-0.2-0.40.10.10.2-0.2-0.20.10.30.30.20.30.30.50.60.7
Cocaine response before conditioning8.19.711.4-3.1-3.1-3.1-3.2-3.2-3.2-3.1-3.1-3.2-3.2-3.2-3.1-3.1-3.1-3.1-3.4-3.0-2.8-2.7
Saline control response0.30.41.4-0.3-0.3-0.3-0.1-0.1-0.5-0.5-0.6-0.2-0.3-0.5-0.7-0.7-0.7-0.70.0-0.9-1.1-1.2
Bone: connectivity density0.00.00.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.20.40.20.20.2
Bone: cortical apparent density0.20.30.7-0.2-0.3-0.30.3-0.2-0.4-0.4-0.4-0.3-0.4-0.5-0.6-0.6-0.6-0.6-0.1-0.8-0.8-0.8
Bone: cortical area0.71.11.5-1.2-1.2-1.2-1.2-0.9-1.1-1.1-1.1-1.0-1.0-1.1-1.0-1.0-1.0-1.0-0.9-0.9-0.8-0.8
Bone: cortical porosity0.70.80.90.90.90.90.30.70.90.90.90.80.80.91.01.01.01.00.81.00.90.9
Bone: cortical porosity0.30.40.80.50.50.5-0.20.20.50.60.60.40.40.60.70.70.70.70.50.80.90.9
Bone: cortical thickness0.20.30.90.70.70.70.81.00.60.50.50.80.80.60.50.50.50.40.50.30.20.1
Bone: cortical thickness0.20.20.5-0.4-0.4-0.4-0.0-0.3-0.4-0.5-0.5-0.4-0.4-0.5-0.6-0.6-0.6-0.6-0.4-0.6-0.7-0.7
Bone: cortical tissue density0.20.20.6-0.2-0.2-0.20.3-0.1-0.3-0.4-0.4-0.3-0.3-0.5-0.6-0.6-0.6-0.6-0.0-0.7-0.7-0.7
Condit. Reinf. active minus inactive responses0.30.30.50.50.50.50.30.60.50.50.50.50.60.50.50.50.50.50.70.50.50.5
Condit. Reinf. active-inactive response ratio2.02.13.31.41.41.41.41.61.41.41.41.51.61.51.41.41.41.41.81.41.31.3
Condit. Reinf. active responses0.10.10.4-0.3-0.3-0.3-0.6-0.4-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.2-0.2
Condit. Reinf. inactive responses3.64.56.1-2.1-2.0-2.1-2.3-2.3-2.1-2.1-2.1-2.2-2.2-2.1-2.1-2.1-2.1-2.1-2.5-2.0-1.9-1.9
Incentive salience index mean0.00.10.1-0.2-0.3-0.3-0.3-0.1-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2-0.2-0.2
Condit. Reinf. lever presses0.71.01.2-1.1-1.1-1.1-0.8-0.9-1.0-1.1-1.1-1.0-1.0-1.1-1.0-1.0-1.0-1.0-1.1-1.0-0.9-0.9
Condit. Reinf. active minus inactive responses3.84.95.7-2.4-2.4-2.4-2.4-2.2-2.3-2.3-2.3-2.2-2.2-2.2-2.2-2.2-2.1-2.1-2.3-2.1-1.9-1.9
Condit. Reinf. active-inactive response ratio4.85.57.4-2.6-2.6-2.6-2.7-2.6-2.5-2.4-2.4-2.5-2.5-2.4-2.2-2.2-2.2-2.2-2.4-2.0-1.7-1.6
Condit. Reinf. active responses3.54.95.5-2.3-2.2-2.2-2.3-2.0-2.3-2.3-2.3-2.1-2.1-2.2-2.2-2.2-2.1-2.1-2.3-2.2-2.2-2.1
Condit. Reinf. inactive responses0.10.10.4-0.2-0.2-0.2-0.4-0.1-0.3-0.3-0.3-0.1-0.2-0.2-0.4-0.4-0.3-0.3-0.5-0.4-0.6-0.6
Condit. Reinf. lever presses0.30.41.7-0.8-0.7-0.8-1.3-1.0-0.6-0.5-0.5-0.7-0.7-0.4-0.3-0.3-0.2-0.2-0.7-0.10.10.2
Condit. Reinf. lever reinforcers received4.46.26.7-2.6-2.5-2.5-2.6-2.3-2.6-2.6-2.6-2.4-2.4-2.5-2.5-2.5-2.4-2.4-2.6-2.5-2.4-2.4
Conditioned reinforcement - actives0.10.10.4-0.4-0.5-0.4-0.2-0.6-0.2-0.3-0.3-0.5-0.5-0.4-0.2-0.1-0.3-0.3-0.2-0.00.10.1
Conditioned reinforcement - inactives2.33.44.2-1.9-1.9-1.9-1.5-1.9-1.8-1.9-1.9-2.0-2.0-2.0-1.8-1.8-1.9-1.9-2.0-1.7-1.6-1.5
Conditioned locomotion0.00.00.2-0.2-0.3-0.2-0.2-0.4-0.1-0.1-0.1-0.3-0.3-0.2-0.0-0.0-0.1-0.1-0.10.10.10.1
Patch foraging indifference point 0 sec0.10.20.80.60.60.60.90.80.50.40.40.60.50.30.30.30.10.10.50.0-0.1-0.2
Patch foraging indifference point AUC0.50.81.01.01.01.00.90.80.91.01.00.90.90.90.90.90.90.90.80.80.80.8
Delay disc. indifference point, 0s delay0.20.30.9-0.2-0.1-0.20.40.3-0.4-0.4-0.4-0.0-0.1-0.4-0.8-0.6-0.6-0.6-0.2-0.8-0.9-0.9
Delay disc. indifference point, 16s delay1.51.62.71.11.01.10.60.71.31.21.31.01.01.31.61.51.51.51.01.61.61.6
Delay disc. indifference point, 2s delay0.30.41.60.60.70.71.30.70.70.50.50.70.70.60.50.40.50.50.60.40.20.1
Delay disc. indifference point, 24s delay0.91.01.51.00.90.90.60.71.01.01.00.90.91.01.21.21.11.10.81.21.21.2
Delay disc. indifference point, 4s delay0.00.00.1-0.2-0.2-0.2-0.0-0.2-0.1-0.2-0.2-0.2-0.1-0.1-0.1-0.1-0.0-0.0-0.2-0.0-0.0-0.0
Delay disc. indifference point, 8s delay0.10.10.20.30.30.30.50.40.30.20.20.30.30.20.20.20.20.20.20.10.10.1
Indifference point function ln k5.18.99.7-3.1-3.0-3.0-2.8-2.7-3.0-3.1-3.1-2.9-2.9-3.1-3.0-3.0-3.1-3.1-3.1-3.0-2.9-2.9
Indifference point function log k5.18.99.7-3.1-3.0-3.0-2.8-2.7-3.0-3.1-3.1-2.9-2.9-3.1-3.0-3.0-3.1-3.1-3.1-3.0-2.9-2.9
Patch foraging total patch changes 0 sec0.10.20.80.50.60.60.90.80.50.40.40.60.50.30.30.30.10.10.50.0-0.1-0.2
Patch foraging total patch changes 12 sec0.30.40.50.70.60.60.50.40.70.70.70.50.50.50.60.70.50.50.70.60.70.7
Patch foraging total patch changes 18 sec0.50.71.10.90.90.91.01.00.80.80.80.90.90.80.70.70.80.81.00.60.60.5
Patch foraging total patch changes 24 sec0.10.10.40.20.10.1-0.2-0.30.20.30.3-0.0-0.00.30.40.40.40.40.30.50.70.7
Patch foraging total patch changes 6 sec0.81.21.61.21.21.21.11.01.21.21.21.11.01.01.11.11.01.01.11.01.00.9
Patch foraging time to switch 0 sec3.67.312.42.32.22.31.61.62.62.72.72.12.22.73.13.13.03.02.73.43.53.5
Patch foraging water rate 0 sec0.81.83.1-1.1-1.1-1.1-0.8-0.7-1.3-1.3-1.3-1.0-1.0-1.4-1.5-1.5-1.5-1.5-1.4-1.7-1.7-1.8
Patch foraging water rate 12 sec2.55.27.4-2.1-2.0-2.1-1.7-1.7-2.3-2.3-2.3-2.0-2.0-2.2-2.5-2.6-2.4-2.4-2.3-2.7-2.7-2.7
Patch foraging water rate 18 sec1.42.23.5-1.4-1.3-1.3-1.0-0.9-1.5-1.5-1.6-1.2-1.2-1.4-1.6-1.6-1.5-1.5-1.5-1.8-1.8-1.9
Patch foraging water rate 24 sec1.31.82.4-1.3-1.2-1.2-1.0-0.9-1.3-1.4-1.4-1.2-1.1-1.4-1.4-1.4-1.5-1.5-1.3-1.5-1.6-1.6
Patch foraging water rate 6 sec5.37.79.6-3.0-3.0-3.0-3.1-3.1-2.9-2.9-2.9-2.9-2.9-2.7-2.7-2.7-2.5-2.5-2.8-2.5-2.3-2.2
Seeking ratio, delayed vs. immediate footshock0.40.51.5-0.4-0.4-0.4-0.10.2-0.6-0.6-0.7-0.2-0.3-0.7-0.9-0.9-0.9-0.9-0.4-1.1-1.2-1.2
Distance traveled before self-admin3.64.78.0-1.9-1.8-1.8-1.1-1.0-2.1-2.2-2.2-1.6-1.6-2.2-2.5-2.5-2.5-2.6-1.8-2.7-2.8-2.8
Distance traveled after self-admin0.20.20.80.20.30.30.40.9-0.1-0.1-0.10.50.4-0.0-0.4-0.4-0.3-0.40.2-0.7-0.9-0.9
Extensor digitorum longus weight0.10.40.8-0.9-0.9-0.9-0.9-0.7-0.7-0.7-0.6-0.7-0.6-0.6-0.5-0.5-0.5-0.5-0.3-0.3-0.1-0.1
Bone: elastic displacement0.20.20.50.60.60.60.40.70.40.50.50.60.50.40.30.30.30.30.10.10.10.1
Bone: elastic work0.60.81.1-0.9-0.8-0.8-0.6-0.7-0.9-0.9-0.9-0.8-0.8-0.9-1.0-1.0-1.0-1.0-1.1-1.0-1.0-1.0
Bone: endosteal estimation2.35.06.8-2.6-2.6-2.6-2.5-2.5-2.4-2.3-2.3-2.4-2.4-2.3-2.1-2.1-2.1-2.0-2.0-1.8-1.5-1.4
Bone: endosteal perimeter1.53.34.4-2.1-2.1-2.1-2.0-1.8-1.9-1.9-1.9-1.9-1.8-1.9-1.7-1.7-1.7-1.7-1.6-1.6-1.3-1.3
Epididymis fat weight0.20.52.00.30.30.3-0.10.10.50.60.60.30.40.70.90.70.91.00.51.11.31.4
Delta time in closed arm before/after self-admin0.00.00.10.30.30.30.4-0.00.30.20.3-0.0-0.0-0.10.20.3-0.1-0.1-0.10.20.20.2
Delta time in open arm before/after self-admin2.02.02.4-1.4-1.4-1.4-1.5-1.1-1.5-1.5-1.5-1.2-1.2-1.4-1.6-1.6-1.5-1.5-1.1-1.6-1.5-1.5
Diff in mean of infusions in LGA sessions0.20.20.7-0.3-0.3-0.30.20.0-0.4-0.5-0.5-0.2-0.2-0.4-0.6-0.6-0.6-0.6-0.3-0.7-0.9-0.9
Delay discount exponential model param0.20.30.5-0.5-0.5-0.5-0.7-0.6-0.6-0.5-0.5-0.6-0.6-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.4-0.4
Extinction: sum of active levers before priming0.00.00.10.20.20.20.10.4-0.10.10.10.30.20.1-0.1-0.20.0-0.00.1-0.2-0.2-0.2
Active lever presses in extinction session 60.70.71.60.50.40.4-0.00.10.70.70.70.50.50.81.01.01.01.00.81.21.31.3
Bone: final force2.03.34.0-2.0-2.0-2.0-1.6-1.9-1.9-1.9-1.9-1.9-1.9-1.9-1.8-1.8-1.8-1.8-1.7-1.7-1.5-1.4
Bone: final moment2.74.35.1-2.3-2.3-2.3-1.8-2.1-2.1-2.2-2.2-2.1-2.1-2.2-2.1-2.1-2.1-2.1-2.0-2.0-1.8-1.7
Food consumed during 24 hour testing period1.72.43.4-1.6-1.6-1.6-1.6-1.8-1.6-1.5-1.5-1.7-1.7-1.6-1.5-1.5-1.5-1.5-1.6-1.4-1.2-1.2
Glucose1.21.83.51.51.51.51.81.91.41.31.31.61.61.31.11.11.11.11.30.90.70.6
Heart weight0.91.42.9-1.4-1.4-1.4-1.7-1.7-1.2-1.2-1.1-1.5-1.4-1.1-1.0-1.0-1.0-0.9-1.1-0.7-0.5-0.5
Delay discount hyperbolic model param0.30.30.7-0.5-0.6-0.6-0.8-0.7-0.6-0.5-0.5-0.6-0.7-0.6-0.6-0.5-0.6-0.6-0.5-0.5-0.4-0.4
Intermittent access intake day 1-15 change0.40.81.1-1.1-1.0-1.0-0.9-0.9-1.0-1.0-1.0-0.8-0.8-0.8-1.0-1.0-0.8-0.7-0.7-0.8-0.7-0.7
Intermittent access intake escalation0.51.11.7-1.3-1.3-1.3-1.1-1.1-1.2-1.2-1.2-1.0-1.0-0.9-1.1-1.1-0.8-0.8-0.9-0.9-0.8-0.8
Intermittent access intake escalation 20.30.30.7-0.6-0.5-0.5-0.2-0.1-0.6-0.6-0.6-0.3-0.3-0.4-0.8-0.8-0.5-0.5-0.4-0.8-0.8-0.9
Intermitt. access day 1 inactive lever presses0.41.42.5-1.3-1.4-1.4-1.5-1.6-1.3-1.2-1.2-1.4-1.4-1.1-1.0-1.0-1.0-1.0-1.2-0.8-0.6-0.5
Intermitt. access day 15 inactive lever presses1.42.85.3-1.7-1.8-1.7-2.2-2.3-1.6-1.5-1.5-2.1-2.1-1.9-1.3-1.3-1.7-1.7-1.8-1.0-0.8-0.7
Intermitt. access escalation Index0.40.50.90.70.70.71.01.00.70.70.70.90.90.70.60.60.60.60.90.60.50.4
Intermittent access day 1 total infusions0.20.30.6-0.7-0.7-0.7-0.5-0.8-0.5-0.6-0.6-0.7-0.7-0.5-0.4-0.4-0.4-0.4-0.5-0.3-0.2-0.2
Intermittent access day 15 total infusions0.40.61.2-1.1-1.1-1.1-0.8-1.0-0.9-0.9-0.9-0.8-0.8-0.6-0.7-0.7-0.5-0.5-0.6-0.5-0.3-0.3
Intermittent access terminal intake (last 3 days)0.50.61.2-1.1-1.0-1.0-0.7-0.9-0.9-0.9-0.9-0.8-0.8-0.6-0.8-0.8-0.5-0.5-0.6-0.6-0.5-0.5
Intermittent access total infusions0.91.11.7-1.3-1.3-1.3-0.9-1.3-1.1-1.1-1.1-1.2-1.1-1.0-1.0-1.0-0.9-0.8-0.9-0.8-0.6-0.6
Intermittent access day 1 locomotion0.81.01.5-1.2-1.2-1.2-0.8-1.2-1.0-1.1-1.1-1.1-1.1-1.0-1.0-1.0-0.9-0.9-1.0-0.9-0.7-0.7
Intermittent access day 15 total locomotion1.22.13.0-1.6-1.6-1.6-0.7-1.0-1.6-1.6-1.7-1.1-1.1-1.3-1.7-1.7-1.4-1.4-1.2-1.7-1.7-1.7
Intermittent access total locomotion2.63.24.4-2.1-2.1-2.1-1.4-1.7-1.9-2.0-2.0-1.7-1.7-1.7-1.9-1.9-1.6-1.6-1.5-1.7-1.6-1.5
Intermittent access standard deviation0.10.30.80.40.40.40.90.90.40.40.40.80.80.70.30.30.60.60.80.20.20.1
Left kidney weight4.521.127.9-5.1-5.1-5.1-5.3-4.9-4.9-4.8-4.7-4.8-4.7-4.6-4.4-4.6-4.3-4.2-4.4-4.0-3.5-3.4
Right kidney weight4.319.529.6-4.9-5.0-4.9-5.4-5.1-4.6-4.5-4.5-4.9-4.8-4.4-4.1-4.0-4.1-4.0-4.4-3.5-3.0-2.8
Cocaine induced anxiety0.81.22.1-1.1-1.1-1.1-1.4-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.0-1.0-1.0-1.0-1.0-0.9-0.9-0.8
Post-drug Anxiety0.30.31.5-0.6-0.6-0.6-1.2-0.8-0.6-0.5-0.4-0.6-0.6-0.4-0.3-0.3-0.3-0.2-0.5-0.1-0.0-0.0
Baseline Anxiety0.80.91.10.90.90.91.00.90.90.90.90.90.91.01.01.01.01.00.80.90.90.9
Tail length2.911.315.1-3.6-3.7-3.6-3.9-3.8-3.5-3.4-3.4-3.7-3.6-3.4-3.2-3.2-3.2-3.2-3.1-2.9-2.5-2.4
Length with tail2.29.815.0-3.6-3.7-3.6-3.9-3.7-3.3-3.3-3.2-3.4-3.4-3.0-2.9-3.0-2.7-2.7-2.7-2.4-2.0-1.9
Length without tail0.72.14.8-2.0-2.0-1.9-2.2-1.9-1.6-1.5-1.5-1.7-1.6-1.3-1.1-1.2-1.0-0.9-1.0-0.6-0.3-0.3
Times rat made contact with spout0.10.20.30.30.30.30.10.10.40.40.40.30.20.40.50.50.50.50.30.50.60.6
Lifetime Intake0.60.71.2-1.0-1.1-1.0-0.7-1.1-0.8-0.9-0.9-1.0-1.0-0.8-0.8-0.8-0.8-0.7-0.8-0.6-0.5-0.5
Liver weight, left0.91.42.1-1.3-1.3-1.3-1.5-1.4-1.2-1.2-1.2-1.3-1.3-1.2-1.1-1.1-1.1-1.1-1.2-0.9-0.8-0.7
Liver weight, right0.00.00.0-0.1-0.1-0.1-0.1-0.1-0.0-0.0-0.0-0.1-0.1-0.00.00.1-0.0-0.0-0.20.10.10.1
Locomotor activity0.10.20.50.40.40.40.20.10.50.50.50.40.30.60.50.50.70.70.20.60.60.6
Locomotor testing distance0.10.10.50.10.00.0-0.3-0.30.20.20.2-0.1-0.10.20.40.40.40.40.10.50.60.7
Locomotor testing rearing0.20.51.0-0.8-0.8-0.8-1.0-0.9-0.7-0.6-0.6-0.8-0.8-0.7-0.6-0.6-0.6-0.6-0.5-0.4-0.2-0.2
Locomotion in novel chamber1.21.62.81.21.21.21.61.61.21.11.11.51.51.40.91.11.31.21.70.90.70.6
Locomotion in novel chamber post-restriction0.61.01.51.00.91.01.21.01.11.01.01.01.01.01.11.11.01.01.01.00.90.9
Fecal boli incidents, locomotor time 10.30.40.5-0.7-0.7-0.7-0.4-0.5-0.7-0.7-0.7-0.6-0.5-0.6-0.7-0.7-0.6-0.6-0.6-0.7-0.7-0.6
Change in fecal boli incidents, locomotor task2.42.44.11.71.71.72.01.81.61.61.61.71.71.51.41.41.41.41.51.21.11.0
Time >=10cm from walls, locomotor time 10.10.10.10.20.20.20.10.10.20.30.30.10.10.20.30.30.20.20.20.30.40.4
Bouts of movement, locomotor time 11.21.43.0-0.8-0.8-0.8-0.3-0.1-1.2-1.1-1.1-0.7-0.6-1.2-1.5-1.5-1.4-1.4-0.8-1.7-1.7-1.7
Total resting periods, locomotor time 10.30.31.0-0.3-0.2-0.30.30.4-0.5-0.5-0.5-0.10.0-0.4-0.8-0.8-0.6-0.6-0.2-1.0-1.0-1.0
Rest time, locomotor task time 11.01.31.6-1.3-1.3-1.3-1.1-1.2-1.2-1.2-1.2-1.2-1.1-1.1-1.2-1.2-1.0-1.0-1.1-1.1-0.9-0.8
Distance moved, locomotor task time 11.01.51.81.31.31.31.11.31.31.21.21.41.31.31.21.21.21.21.21.10.90.8
Vertical activity count, locomotor time 10.82.04.61.61.71.62.02.11.41.31.31.81.81.41.11.11.21.11.40.70.40.4
Time >=10cm from walls, locomotor time 20.71.11.21.11.11.10.90.91.11.11.11.00.91.01.11.11.01.01.01.01.01.0
Bouts of movement, locomotor time 20.00.00.0-0.1-0.1-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.0
Total resting periods, locomotor time 20.00.00.1-0.2-0.2-0.2-0.0-0.1-0.2-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2
Rest time, locomotor task time 20.10.20.4-0.2-0.2-0.20.10.0-0.3-0.4-0.4-0.2-0.2-0.4-0.5-0.5-0.5-0.5-0.3-0.6-0.6-0.6
Distance moved, locomotor task time 20.10.20.20.40.50.50.30.40.40.40.40.50.40.50.40.40.40.40.40.40.30.3
Vertical activity count, locomotor time 20.10.20.50.40.40.40.60.70.30.30.30.60.60.40.30.30.40.40.40.20.10.0
Light reinforcement 10.10.31.2-0.0-0.0-0.00.50.3-0.2-0.3-0.3-0.0-0.1-0.5-0.6-0.6-0.7-0.80.1-0.8-1.0-1.1
Light reinforcement 21.01.53.11.31.31.31.81.81.21.11.11.51.51.20.90.91.01.01.60.70.50.4
Bone: marrow area2.34.96.8-2.6-2.6-2.6-2.5-2.5-2.4-2.3-2.3-2.4-2.3-2.3-2.1-2.1-2.1-2.0-2.0-1.8-1.4-1.4
Bone: maximum diameter0.61.22.3-1.4-1.4-1.4-1.5-1.1-1.2-1.2-1.2-1.2-1.1-1.1-0.9-0.9-0.9-0.9-0.9-0.7-0.5-0.5
Bone: maximum force2.64.76.0-2.4-2.5-2.4-2.3-2.4-2.3-2.3-2.2-2.3-2.3-2.2-2.1-2.1-2.1-2.0-1.9-1.9-1.6-1.5
Bone: maximum moment3.25.77.1-2.6-2.7-2.7-2.4-2.5-2.5-2.5-2.5-2.5-2.5-2.5-2.3-2.3-2.3-2.3-2.2-2.1-1.9-1.8
Mean time between licks in bursts0.10.30.90.70.80.70.90.70.60.50.50.70.60.50.40.40.40.30.30.2-0.0-0.1
Mean num. licks in bursts0.00.00.1-0.3-0.3-0.3-0.3-0.3-0.2-0.2-0.2-0.3-0.2-0.2-0.1-0.1-0.1-0.1-0.10.00.10.2
Cd content in liver2.32.62.8-1.7-1.7-1.7-1.6-1.6-1.6-1.7-1.7-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.4-1.6-1.5-1.4
Co content in liver1.51.83.0-1.1-1.1-1.1-0.5-1.1-1.2-1.3-1.3-1.1-1.3-1.4-1.5-1.5-1.5-1.5-1.1-1.7-1.7-1.7
Cu content in liver0.70.91.5-1.0-1.0-1.0-1.0-1.2-0.9-1.0-0.9-1.1-1.1-0.9-0.9-0.9-0.9-0.9-0.6-0.8-0.7-0.7
Fe content in liver0.20.30.4-0.6-0.6-0.6-0.5-0.5-0.6-0.6-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.3-0.5-0.4-0.4
K content in liver0.00.00.10.10.00.1-0.2-0.30.00.10.1-0.1-0.20.00.00.00.00.00.20.00.00.0
Mg content in liver0.30.30.60.40.40.40.10.10.50.50.60.30.30.50.60.60.60.60.80.70.80.8
Mn content in liver0.10.10.40.20.20.2-0.30.10.20.30.40.20.30.30.40.40.40.40.60.50.60.6
Na content in liver2.62.83.61.91.91.91.51.51.81.81.81.71.61.71.71.71.71.71.91.51.41.3
Rb content in liver1.92.24.6-1.6-1.7-1.6-2.2-2.0-1.5-1.5-1.4-1.8-1.7-1.4-1.3-1.3-1.3-1.2-1.4-1.0-0.8-0.8
Se content in liver2.93.44.31.71.71.71.52.01.81.81.81.92.01.91.91.91.91.92.11.91.91.9
Sr content in liver3.63.17.42.12.12.12.72.51.81.71.72.22.11.61.31.31.31.31.90.90.70.6
Zn content in liver1.01.12.00.90.90.90.60.41.11.11.10.70.81.11.21.21.21.21.11.41.41.4
Bone: minimum diameter3.15.77.6-2.6-2.6-2.6-2.7-2.5-2.5-2.5-2.4-2.5-2.5-2.4-2.3-2.3-2.3-2.3-2.4-2.1-1.9-1.8
Time in familiar zone, hab. session 14.64.56.0-2.1-2.1-2.1-1.3-1.6-2.1-2.2-2.2-1.9-1.9-2.2-2.3-2.3-2.3-2.3-1.8-2.5-2.3-2.3
Time in novel zone, hab. session 12.92.93.31.81.81.81.31.51.81.81.81.71.71.81.81.81.81.81.51.81.61.6
Total zone transitions, hab. session 11.62.24.5-1.1-1.1-1.1-0.7-0.8-1.3-1.4-1.4-1.1-1.2-1.4-1.7-1.7-1.7-1.7-1.7-1.8-2.1-2.1
Total locomotion distance, hab. session 10.70.92.4-0.6-0.6-0.6-0.2-0.2-0.8-0.9-0.9-0.6-0.6-0.9-1.1-1.1-1.1-1.1-1.1-1.3-1.5-1.5
Locomotion velocity, hab. session 10.50.71.6-0.5-0.5-0.5-0.2-0.2-0.7-0.8-0.8-0.5-0.5-0.8-0.9-0.9-0.9-1.0-1.0-1.0-1.3-1.3
Time in familiar zone, hab. session 22.02.13.9-1.7-1.7-1.7-1.9-2.0-1.5-1.5-1.4-1.7-1.7-1.4-1.2-1.2-1.2-1.2-1.2-1.0-0.7-0.6
Time in novel zone, hab. session 21.51.62.51.41.51.41.41.61.31.31.31.41.41.31.11.11.11.11.01.00.80.7
Total zone transitions, hab. session 23.03.84.7-1.8-1.8-1.8-1.8-1.6-1.9-2.0-2.0-1.8-1.8-1.9-2.0-2.0-2.0-2.0-2.2-2.0-2.1-2.1
Total locomotion distance, hab. session 20.20.30.9-0.3-0.3-0.3-0.00.1-0.4-0.5-0.5-0.3-0.2-0.5-0.6-0.6-0.6-0.7-0.7-0.7-0.9-1.0
Locomotion velocity, hab. session 20.20.20.9-0.2-0.1-0.20.10.2-0.3-0.4-0.4-0.1-0.1-0.4-0.6-0.6-0.6-0.6-0.6-0.7-0.9-1.0
Novel to familiar place preference ratio0.00.00.0-0.1-0.1-0.1-0.2-0.1-0.0-0.0-0.0-0.0-0.0-0.00.00.00.00.00.10.10.10.1
Novelty place preference0.10.10.2-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.1
Time in novel zone, NPP test0.10.10.2-0.4-0.4-0.4-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.1-0.2-0.1-0.1
Total zone transitions, NPP test0.60.81.4-0.7-0.7-0.7-0.6-0.8-0.8-0.9-0.9-0.8-0.9-0.9-0.9-0.9-0.9-1.0-1.2-1.0-1.1-1.1
Total locomotion distance, NPP test0.40.51.0-0.7-0.7-0.7-0.8-0.8-0.7-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.7-0.7-1.0-0.6-0.6-0.6
Locomotion velocity, NPP test0.50.71.3-0.7-0.7-0.7-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.8-1.1-0.8-0.9-0.9
Intraocular pressure0.00.00.10.10.20.20.30.10.10.10.10.20.10.10.00.00.10.10.1-0.1-0.1-0.1
Delta distance traveled before/after self-admin2.42.63.01.61.61.61.31.61.61.61.61.71.71.71.71.71.71.71.61.61.41.4
Delta ambulatory time before/after self-admin1.41.72.01.41.41.41.21.31.41.41.41.31.31.41.31.41.31.31.21.31.11.1
Parametrial fat weight1.84.24.62.12.12.12.12.12.12.12.12.12.12.12.12.02.02.01.92.11.91.8
Pavlov. Cond. lever latency0.10.10.20.30.30.30.30.30.20.20.20.30.30.20.20.20.20.10.40.00.00.0
Pavlov. Cond. magazine entry latency0.91.11.51.01.01.00.90.81.11.11.10.91.01.11.21.21.21.20.81.21.21.2
Pavlov. Cond. change in total contacts0.20.20.40.50.50.50.60.50.50.50.50.50.50.50.50.50.50.50.40.50.30.3
Pavlov. Cond. index score0.30.40.40.60.60.60.60.60.60.60.60.60.60.60.60.60.60.60.40.70.60.6
Pavlov. Cond. latency score0.20.30.40.50.50.50.50.50.60.50.50.50.50.60.60.60.60.60.30.60.50.5
Pavlov. Cond. lever contacts0.00.10.2-0.3-0.3-0.3-0.4-0.3-0.1-0.1-0.1-0.3-0.2-0.10.00.00.00.0-0.30.20.20.3
Pavlov. Cond. magazine entry number0.30.40.6-0.6-0.6-0.6-0.5-0.4-0.7-0.6-0.7-0.5-0.5-0.7-0.7-0.7-0.7-0.7-0.4-0.8-0.7-0.7
Pavlov. Cond. intertrial magazine entries0.30.31.4-0.1-0.1-0.10.10.2-0.3-0.4-0.4-0.1-0.1-0.4-0.6-0.6-0.6-0.7-0.4-0.9-1.1-1.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.50.60.60.60.60.60.70.60.60.60.70.70.70.70.70.70.40.70.60.6
Pavlov. Cond. response bias0.10.20.50.20.20.20.0-0.00.30.40.40.20.20.40.50.50.50.50.20.60.70.7
Pavlov. Cond. lever latency0.30.40.5-0.6-0.6-0.6-0.4-0.7-0.6-0.6-0.6-0.7-0.7-0.7-0.6-0.6-0.7-0.7-0.3-0.5-0.5-0.4
Pavlov. Cond. magazine entry latency1.01.21.31.11.11.10.91.11.01.11.11.11.11.11.11.11.11.11.01.01.11.1
Pavlov. Cond. change in total contacts0.10.20.4-0.5-0.4-0.4-0.5-0.3-0.5-0.5-0.5-0.3-0.4-0.4-0.5-0.5-0.5-0.5-0.6-0.6-0.6-0.7
Pavlov. Cond. index score0.10.10.10.30.30.30.00.30.30.30.30.30.30.30.30.30.40.30.10.30.40.3
Pavlov. Cond. latency score0.40.50.60.70.80.80.50.70.70.80.80.80.80.80.70.70.80.80.50.70.70.7
Pavlov. Cond. lever contacts0.10.10.20.30.30.30.10.40.30.30.30.40.40.40.30.30.40.40.00.30.30.2
Pavlov. Cond. magazine entry number0.50.60.8-0.8-0.8-0.8-0.8-0.9-0.8-0.8-0.8-0.9-0.9-0.8-0.8-0.8-0.8-0.8-0.7-0.7-0.7-0.7
Pavlov. Cond. intertrial magazine entries3.04.45.2-2.2-2.2-2.2-2.3-2.3-2.2-2.2-2.2-2.2-2.2-2.1-2.1-2.1-2.0-2.0-2.0-1.9-1.8-1.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.40.40.40.20.50.30.40.40.50.40.40.40.40.40.40.10.30.40.3
Pavlov. Cond. response bias0.10.10.5-0.3-0.3-0.3-0.6-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.7-0.2-0.1-0.2
Time in closed arm before self-admin0.60.81.1-1.0-1.0-1.0-1.1-0.9-1.0-1.0-1.0-0.9-0.9-0.9-0.9-0.9-0.8-0.8-0.7-0.8-0.8-0.7
Time in closed arm after self-admin0.10.10.2-0.1-0.1-0.1-0.3-0.50.10.00.0-0.3-0.3-0.10.20.2-0.00.0-0.20.30.30.4
Time in open arm before self-admin2.02.22.81.71.61.61.71.41.71.61.61.41.41.41.51.51.31.31.21.41.31.2
Time in open arm after self-admin0.10.10.40.30.30.30.40.60.10.20.10.40.40.2-0.0-0.00.00.00.4-0.2-0.2-0.2
Bone: periosteal estimation1.83.85.2-2.3-2.3-2.3-2.2-2.0-2.1-2.1-2.1-2.1-2.0-2.0-1.9-1.9-1.9-1.8-1.8-1.7-1.4-1.3
Bone: periosteal perimeter1.62.83.6-1.9-1.9-1.9-1.8-1.5-1.8-1.8-1.8-1.6-1.6-1.7-1.6-1.6-1.6-1.6-1.5-1.5-1.4-1.3
Bone: post-yield work2.13.05.4-2.1-2.1-2.1-2.3-2.1-1.9-1.8-1.8-2.0-1.9-1.7-1.5-1.5-1.5-1.5-1.2-1.2-0.9-0.8
Progressive ratio test 1 active lever presses1.01.21.6-1.0-1.0-1.0-0.6-0.8-1.1-1.1-1.1-1.0-1.0-1.2-1.2-1.2-1.2-1.2-1.0-1.3-1.2-1.2
Progressive ratio test 1 breakpoint0.91.11.5-1.0-1.0-1.0-0.5-0.8-1.0-1.1-1.1-1.0-1.0-1.1-1.2-1.2-1.2-1.2-1.0-1.2-1.2-1.2
Progressive ratio test 1 inactive lever presses2.73.94.7-2.0-2.0-2.0-1.7-2.1-1.9-2.0-1.9-2.2-2.2-2.1-1.9-1.9-2.1-2.1-2.2-1.8-1.6-1.6
Progressive ratio test 2 active lever presses0.20.20.6-0.7-0.7-0.7-0.6-0.8-0.5-0.5-0.5-0.6-0.6-0.3-0.3-0.3-0.2-0.2-0.4-0.1-0.0-0.0
Progressive ratio test 2 breakpoint0.30.30.8-0.8-0.8-0.8-0.7-0.9-0.5-0.6-0.6-0.7-0.7-0.4-0.4-0.4-0.3-0.2-0.5-0.1-0.0-0.0
Progressive ratio test 2 inactive lever presses2.54.14.9-2.2-2.2-2.2-2.0-2.2-2.0-2.1-2.1-2.2-2.2-2.1-2.0-1.9-2.0-2.0-2.0-1.7-1.6-1.6
Incentive Sensitization - Responses0.60.82.0-1.2-1.2-1.2-1.4-1.4-1.0-0.9-0.9-1.0-1.0-0.7-0.6-0.6-0.4-0.4-0.7-0.3-0.1-0.1
Incentive Sensitization - Breakpoint0.30.51.4-1.0-1.0-0.9-1.2-1.1-0.7-0.7-0.6-0.8-0.8-0.4-0.4-0.4-0.2-0.2-0.4-0.10.10.1
Sum of active levers in priming session hrs 5-60.10.10.2-0.00.0-0.00.00.3-0.2-0.1-0.10.20.2-0.0-0.3-0.3-0.2-0.20.1-0.4-0.4-0.4
Progressive ratio0.10.10.3-0.1-0.1-0.1-0.3-0.0-0.3-0.2-0.2-0.2-0.2-0.4-0.4-0.5-0.5-0.5-0.4-0.5-0.5-0.5
Food seeking constrained by brief footshock2.42.98.1-0.8-0.7-0.70.20.2-1.3-1.4-1.4-0.7-0.8-1.7-2.1-2.1-2.3-2.3-1.3-2.6-2.8-2.8
Seeking ratio, punishment vs. effort0.71.11.7-1.0-0.9-0.9-0.4-0.6-1.0-1.1-1.1-0.8-0.8-1.0-1.3-1.1-1.1-1.1-0.9-1.2-1.3-1.3
Retroperitoneal fat weight4.921.023.14.64.54.64.34.24.74.74.74.54.54.74.84.64.74.74.54.74.64.6
Reaction time number correct0.10.10.40.40.40.40.50.60.30.30.30.50.50.30.20.20.20.20.20.10.10.0
Reaction time mean minus median0.00.00.0-0.0-0.1-0.00.00.2-0.1-0.0-0.00.10.10.1-0.1-0.10.10.10.0-0.1-0.0-0.0
Reaction time mean minus median AUC0.00.00.10.10.10.10.10.30.10.20.20.20.30.20.20.20.20.30.30.20.30.3
Reaction time num false alarms0.00.00.0-0.1-0.1-0.00.20.20.1-0.1-0.10.10.10.10.00.00.00.00.2-0.0-0.1-0.1
Reaction time num false alarms AUC0.10.10.50.20.30.30.70.70.30.10.10.50.40.20.10.10.10.00.5-0.1-0.3-0.3
Reaction time trials correct on left0.10.10.40.40.40.40.50.60.30.30.30.50.50.30.20.20.20.20.20.10.10.0
Reaction time trials on left0.10.10.40.30.40.40.50.60.30.30.30.50.50.30.20.20.20.20.20.10.00.0
Reaction time mean0.30.61.3-0.8-0.9-0.9-1.1-1.1-0.8-0.7-0.7-0.9-0.9-0.7-0.6-0.6-0.6-0.5-0.6-0.5-0.3-0.2
Reaction time mean AUC0.10.10.4-0.4-0.4-0.4-0.7-0.7-0.3-0.3-0.2-0.5-0.4-0.2-0.1-0.1-0.1-0.1-0.1-0.00.20.2
Median of all reaction times0.40.51.4-0.8-0.8-0.8-1.1-1.2-0.7-0.6-0.6-0.9-0.9-0.7-0.5-0.5-0.5-0.5-0.6-0.3-0.2-0.1
Reaction time omissions0.10.10.30.00.00.00.40.5-0.1-0.1-0.10.20.3-0.1-0.3-0.3-0.2-0.20.2-0.5-0.5-0.6
Reaction time false alarm rate0.00.00.20.00.00.10.40.30.1-0.1-0.10.20.20.0-0.1-0.1-0.1-0.10.3-0.2-0.3-0.4
Reaction time premature initiation rate0.00.00.1-0.0-0.1-0.1-0.2-0.3-0.00.00.0-0.1-0.10.00.00.00.10.10.10.10.20.2
Reaction time premature initiations0.10.10.20.20.20.20.10.10.30.30.30.20.20.30.30.30.40.40.30.40.40.4
Std. dev. reaction times0.20.30.7-0.7-0.7-0.7-0.9-0.7-0.6-0.6-0.6-0.7-0.6-0.5-0.5-0.5-0.3-0.3-0.5-0.4-0.2-0.2
Reaction time trials completed0.10.10.40.30.40.40.50.60.30.30.30.50.50.30.20.20.20.20.20.10.00.0
Reaction time trials AUC0.10.10.30.30.30.30.40.60.30.30.30.40.50.30.20.20.30.30.20.20.20.1
Run reversals in cocaine runway, females0.20.20.6-0.4-0.4-0.4-0.8-0.8-0.3-0.2-0.2-0.6-0.6-0.4-0.1-0.1-0.3-0.3-0.30.00.20.2
Run reversals in cocaine runway, males0.00.00.1-0.0-0.1-0.10.1-0.20.0-0.0-0.0-0.1-0.2-0.00.00.0-0.0-0.00.0-0.00.10.1
Latency to leave start box in cocaine runway0.50.50.7-0.7-0.7-0.7-0.8-0.9-0.8-0.7-0.7-0.8-0.8-0.7-0.7-0.8-0.7-0.7-0.7-0.6-0.6-0.5
Latency to leave start box in cocaine runway, F0.10.10.1-0.2-0.2-0.2-0.2-0.3-0.3-0.2-0.2-0.3-0.3-0.3-0.2-0.3-0.3-0.3-0.3-0.3-0.2-0.2
Latency to leave start box in cocaine runway, M1.21.11.6-1.3-1.2-1.2-1.2-1.2-1.1-1.2-1.2-1.1-1.1-0.9-1.1-1.1-0.8-0.8-1.0-0.8-0.9-0.8
Std. dev. time between licks in bursts0.20.31.40.00.10.10.30.2-0.2-0.3-0.30.0-0.1-0.3-0.5-0.5-0.5-0.6-0.6-0.9-1.1-1.2
Total sessions with >9 infusions1.11.31.8-1.2-1.2-1.2-0.7-1.0-1.1-1.2-1.2-1.1-1.1-1.3-1.2-1.2-1.3-1.3-1.0-1.2-1.1-1.1
Short access day 1 total inactive lever presses0.30.41.1-0.8-0.9-0.8-0.9-1.0-0.6-0.6-0.6-0.8-0.8-0.5-0.4-0.3-0.4-0.4-0.6-0.2-0.1-0.0
Short access day 10 total inactive lever presses0.10.10.2-0.5-0.5-0.5-0.3-0.4-0.4-0.4-0.4-0.4-0.4-0.3-0.3-0.4-0.2-0.2-0.4-0.3-0.3-0.2
Short access day 1 total infusions0.00.00.1-0.1-0.1-0.10.2-0.1-0.0-0.1-0.1-0.1-0.1-0.2-0.1-0.1-0.2-0.2-0.1-0.1-0.1-0.1
Short access day 10 total infusions0.00.00.10.10.10.10.40.10.10.00.00.00.0-0.0-0.0-0.0-0.1-0.10.0-0.0-0.0-0.1
Short access total infusions0.00.00.40.20.20.20.60.20.30.20.20.10.10.10.20.20.00.00.10.20.10.1
Short access day 1 locomotion0.20.30.6-0.6-0.6-0.6-0.4-0.7-0.4-0.5-0.5-0.7-0.7-0.6-0.4-0.3-0.5-0.5-0.5-0.2-0.2-0.2
Short access day 10 total locomotion1.01.83.0-1.3-1.2-1.2-0.5-0.7-1.3-1.4-1.4-1.0-1.0-1.3-1.6-1.6-1.5-1.5-1.1-1.7-1.7-1.7
Short access total locomotion0.80.92.0-0.8-0.7-0.70.1-0.2-0.8-1.0-1.0-0.6-0.6-0.9-1.2-1.2-1.1-1.2-0.7-1.3-1.4-1.4
One hour access (0.3 mA shock)3.33.85.2-2.3-2.3-2.2-2.1-2.2-2.1-2.1-2.1-2.1-2.1-1.9-1.9-1.9-1.8-1.8-1.8-1.6-1.4-1.4
Compulsive drug intake1.72.02.7-1.6-1.6-1.6-1.7-1.4-1.6-1.5-1.5-1.3-1.3-1.3-1.4-1.4-1.2-1.2-1.3-1.3-1.1-1.1
One hour access (shock baseline)0.10.10.6-0.4-0.4-0.4-0.4-0.8-0.2-0.2-0.2-0.6-0.6-0.4-0.1-0.1-0.2-0.2-0.40.10.20.3
Social response proportion0.40.41.4-0.8-0.8-0.8-1.1-1.2-0.6-0.6-0.6-0.9-0.9-0.5-0.4-0.4-0.3-0.3-0.6-0.2-0.00.0
Social responses2.53.35.2-1.9-1.9-1.9-2.2-2.3-1.8-1.8-1.8-2.1-2.1-1.8-1.6-1.6-1.7-1.6-1.8-1.4-1.3-1.2
Social time4.56.27.4-2.4-2.3-2.4-2.2-2.2-2.4-2.5-2.5-2.4-2.4-2.6-2.6-2.5-2.7-2.7-2.7-2.5-2.6-2.6
Soleus weight0.00.10.1-0.3-0.3-0.3-0.2-0.1-0.3-0.2-0.2-0.1-0.1-0.2-0.2-0.2-0.2-0.20.3-0.2-0.1-0.1
Bone: stiffness2.33.84.8-2.2-2.2-2.2-2.1-2.2-2.0-2.0-2.0-2.1-2.1-2.0-1.9-1.9-1.9-1.9-1.7-1.7-1.4-1.4
Tibialis anterior weight1.13.74.31.71.71.71.72.01.81.81.82.02.11.92.02.02.02.02.12.02.02.0
Time to tail flick, vehicle, before self-admin0.80.81.3-0.8-0.8-0.8-0.6-0.5-0.9-0.9-0.9-0.7-0.7-0.9-1.1-1.1-1.0-1.0-0.8-1.1-1.1-1.1
Time to tail flick, vehicle, after self-admin0.10.10.3-0.5-0.5-0.5-0.5-0.6-0.4-0.3-0.3-0.3-0.3-0.1-0.2-0.20.10.1-0.2-0.00.10.1
Time to tail flick, test, before self-admin0.30.31.0-0.1-0.0-0.00.90.7-0.2-0.3-0.30.30.3-0.1-0.6-0.6-0.3-0.30.1-0.8-1.0-1.0
Time to tail flick, test, after self-admin0.30.30.50.60.60.60.20.30.60.60.60.30.30.30.60.70.30.40.40.70.70.7
Delta time to tail flick, vehicle, before/after SA0.60.51.10.40.40.40.50.30.70.60.60.60.60.90.90.81.01.10.61.00.91.0
Delta time to tail flick, test, before/after SA0.20.20.80.1-0.0-0.0-0.9-0.70.10.20.2-0.5-0.4-0.20.40.4-0.0-0.0-0.20.60.70.7
Tibia length3.08.212.7-3.2-3.2-3.2-3.6-3.4-3.0-2.9-2.9-3.2-3.1-2.9-2.6-2.6-2.6-2.6-2.9-2.3-1.9-1.8
Ambulatory time before self-admin2.53.75.7-1.7-1.6-1.7-1.2-1.0-1.9-1.9-2.0-1.5-1.5-2.0-2.2-2.2-2.2-2.3-1.6-2.4-2.4-2.4
Ambulatory time after self-admin0.60.72.0-0.4-0.4-0.4-0.30.2-0.7-0.7-0.7-0.3-0.3-0.8-1.0-1.0-1.1-1.1-0.5-1.2-1.4-1.4
Bone: tissue strength0.60.61.4-0.6-0.6-0.60.0-0.1-0.7-0.8-0.8-0.4-0.4-0.8-0.9-0.9-0.9-0.9-0.6-1.1-1.2-1.2
Total heroin consumption0.00.00.10.10.10.1-0.00.3-0.10.0-0.00.10.1-0.0-0.2-0.2-0.1-0.10.1-0.2-0.2-0.2
Bone: trabecular number0.10.10.30.40.40.40.50.30.40.30.30.30.30.30.30.30.30.20.30.20.10.1
Bone: trabecular spacing0.00.00.10.00.00.00.00.10.10.10.10.10.10.10.20.20.20.20.00.20.20.3
Bone: trabecular thickness0.00.00.1-0.0-0.0-0.0-0.0-0.1-0.0-0.0-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.00.2-0.00.00.0
Bone: trabecular tissue density1.01.52.11.21.21.20.70.81.21.31.31.01.01.21.31.31.31.31.31.41.41.4
Water consumed over 24 hours1.21.61.8-1.2-1.2-1.2-1.0-1.2-1.2-1.3-1.3-1.2-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3
Number of responses in last shaping day0.10.10.20.20.10.10.1-0.30.20.20.2-0.2-0.2-0.10.30.30.00.0-0.10.40.40.5