Hub : Genes

Synj2bp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Synj2bp 0.09 0.08 6.7e-03 0.01 0.02 0.04 0.02 2.8e-02 6.2e-03 1.5e-04 1.5e-02
2 BLA gene expression Synj2bp 0.07 0.04 2.6e-03 0.02 0.02 0.01 0.02 2.7e-02 3.3e-02 1.3e-01 2.0e-02
3 OFC gene expression Synj2bp 0.6 0.19 4.0e-03 0.05 0.04 0.01 0.04 2.7e-02 4.0e-02 2.1e-01 4.5e-02
4 Brain mRNA stability Synj2bp 0.14 0.06 1.7e-15 0.18 0.16 0.17 0.17 2.2e-16 6.3e-15 2.1e-15 7.0e-16
5 Brain gene expression Synj2bp 0.15 0.06 0.0e+00 0.22 0.21 0.21 0.21 4.5e-20 2.3e-19 3.7e-19 1.9e-19
6 Adipose mRNA stability Synj2bp 0.04 0.02 1.8e-04 0.02 0.04 0.04 0.03 1.3e-03 5.7e-05 7.7e-05 2.1e-04
7 PL mRNA stability Synj2bp 0.08 0.04 2.2e-09 0.09 0.09 0.09 0.09 1.6e-09 5.6e-10 1.2e-09 2.5e-10
8 NAcc gene expression Synj2bp 0.12 0.05 0.0e+00 0.14 0.13 0.13 0.14 3.3e-20 1.5e-19 1.4e-19 2.2e-20
9 NAcc mRNA stability Synj2bp 0.03 0.02 8.3e-04 0.03 0.02 0.02 0.03 7.8e-06 3.5e-04 3.0e-04 1.0e-04
10 PL gene expression Synj2bp 0.08 0.04 7.5e-10 0.07 0.1 0.09 0.09 5.2e-08 8.4e-11 7.0e-10 1.2e-09
11 IC gene expression Synj2bp 0.15 0.09 2.5e-03 0.02 0.05 0.02 0.03 3.9e-02 5.3e-03 3.6e-02 1.7e-02
12 pVTA mRNA stability Synj2bp 0.04 0.02 2.2e-03 0.03 0.03 0.02 0.03 2.2e-03 1.6e-03 4.5e-03 3.8e-03
13 Adipose gene expression Synj2bp 0.06 0.03 3.9e-04 0.03 0.02 0.03 0.02 4.2e-04 3.9e-03 2.0e-04 3.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.21.8-0.1-0.5-0.4-0.20.30.10.00.1-0.1-0.0-0.00.3-1.4
Area under the delay curve0.20.30.90.5-0.6-0.30.2-0.20.70.6-0.20.2-0.9-0.50.9-0.5
BMI with tail0.51.65.72.41.4-1.6-1.51.3-0.4-0.01.4-1.50.30.11.1-0.8
BMI without tail0.72.26.20.6-1.8-2.50.9-0.51.71.7-1.00.6-1.0-1.61.7-1.9
Body weight1.46.310.2-2.2-3.2-2.12.5-2.62.93.2-2.62.2-2.2-2.32.3-2.2
Weight adjusted by age0.71.04.70.6-1.7-0.20.3-0.21.82.2-0.50.5-0.6-0.80.3-0.2
Bone surface0.10.20.7-0.0-0.40.3-0.50.50.30.70.4-0.60.30.4-0.2-0.8
Bone volume0.20.32.3-0.7-0.70.2-0.20.20.20.40.1-0.10.10.3-0.1-1.5
Breakpoint value in progressive ratio session0.70.83.31.80.50.6-0.91.00.10.50.7-1.10.90.5-0.91.0
Number of licking bursts0.40.62.41.61.2-0.1-0.80.9-0.7-0.60.8-0.60.60.3-0.00.4
Context. condit. distance diff. score1.31.62.5-1.5-1.1-0.71.5-1.51.10.9-1.51.4-1.6-1.31.2-0.4
Locomotion velocity, session 10.70.82.0-0.51.10.9-0.70.7-0.9-0.60.7-0.51.31.0-1.40.6
Locomotion distance, session 10.91.12.01.41.1-0.5-1.31.3-1.0-1.21.4-1.20.80.6-0.2-0.6
Locomotion velocity, session 20.30.41.50.10.70.0-0.30.2-0.9-1.20.4-0.10.20.20.1-1.2
Locomotion distance, session 21.72.34.51.61.8-0.2-1.81.8-1.8-2.11.9-1.71.41.1-0.7-0.4
Locomotion velocity, session 30.60.73.2-1.8-0.80.70.7-0.8-0.2-0.8-0.50.6-0.70.00.0-1.1
Locomotion distance, session 30.10.10.6-0.3-0.30.5-0.10.1-0.0-0.10.2-0.2-0.30.3-0.0-0.8
Stereotopy head waving bouts, day 30.60.71.8-0.7-1.3-0.00.9-0.90.81.0-0.80.6-0.8-0.50.5-1.2
Stereotopy head waving duration, day 30.30.31.4-1.0-0.80.40.5-0.60.00.1-0.40.4-0.20.0-0.2-1.2
Locomotion velocity, session 70.50.61.5-0.70.31.2-0.60.4-0.9-1.00.6-0.70.41.1-0.80.3
Locomotion distance, session 70.20.31.10.60.3-1.0-0.50.4-0.4-0.80.4-0.4-0.2-0.10.7-0.7
Stereotopy head waving bouts, day 71.31.44.7-1.1-2.2-0.11.3-1.41.31.3-1.21.1-1.1-0.80.5-0.9
Stereotopy head waving duration, day 71.51.85.8-1.3-2.4-0.41.5-1.51.21.1-1.31.3-1.1-0.90.6-1.4
Locomotion velocity, session 80.20.30.80.20.90.0-0.40.3-0.8-0.90.5-0.30.40.3-0.3-0.0
Locomotion distance, session 80.20.31.10.00.1-1.10.0-0.0-0.1-0.60.1-0.0-0.6-0.50.9-1.0
Degree of sensitization distance0.20.21.3-0.3-0.0-1.10.3-0.30.1-0.1-0.40.4-0.3-0.60.60.2
Degree of sensitization stereotypy1.41.54.0-1.3-2.0-0.21.4-1.41.41.2-1.41.4-1.2-1.00.6-0.5
Conditioned locomotion1.01.13.9-0.91.22.0-0.30.4-1.3-1.30.5-0.40.91.0-1.40.9
Cocaine response after cond. corrected1.31.64.00.71.62.0-1.11.1-1.5-1.31.1-1.11.01.5-1.10.8
Cocaine response after cond. not corrected1.92.33.21.31.81.7-1.51.5-1.8-1.71.5-1.51.31.7-1.30.6
Cocaine response before conditioning0.40.52.11.4-0.0-0.7-0.90.9-0.3-0.50.9-0.90.60.4-0.3-0.5
Saline control response0.30.31.10.60.4-0.4-0.60.5-0.7-1.10.7-0.60.20.30.1-0.8
Bone: connectivity density0.20.31.10.4-0.5-0.8-0.20.20.50.60.1-0.1-0.2-0.40.7-1.1
Bone: cortical apparent density0.30.51.4-0.50.0-0.60.6-0.60.1-0.3-0.60.7-1.1-0.61.2-0.8
Bone: cortical area0.40.72.8-1.7-1.10.50.9-0.90.71.0-0.80.7-0.4-0.2-0.20.1
Bone: cortical porosity1.31.43.6-1.0-1.9-1.01.1-1.21.61.6-1.10.9-0.8-1.20.60.3
Bone: cortical porosity1.51.63.6-1.4-1.9-0.91.2-1.31.81.8-1.21.1-0.9-1.30.50.4
Bone: cortical thickness0.40.61.4-1.2-0.9-1.10.8-0.90.50.2-0.60.6-0.8-0.80.7-0.4
Bone: cortical thickness0.40.51.70.50.80.4-0.60.5-0.9-1.30.7-0.70.30.4-0.31.1
Bone: cortical tissue density0.30.41.2-0.50.1-0.50.6-0.60.0-0.3-0.60.6-1.0-0.61.1-0.7
Condit. Reinf. active minus inactive responses2.02.23.3-0.8-1.7-0.81.8-1.71.71.5-1.81.7-1.7-1.61.20.0
Condit. Reinf. active-inactive response ratio2.12.23.3-0.8-1.7-0.71.8-1.71.81.5-1.81.8-1.8-1.51.3-0.0
Condit. Reinf. active responses2.32.93.9-1.2-1.7-1.31.9-1.92.01.7-1.91.9-1.9-1.91.50.6
Condit. Reinf. inactive responses0.30.42.20.0-0.0-1.50.3-0.40.60.6-0.30.2-0.4-0.90.70.8
Incentive salience index mean1.21.52.2-0.7-1.3-0.61.5-1.41.51.3-1.51.4-1.3-1.20.90.7
Condit. Reinf. lever presses0.10.11.10.0-0.2-0.20.2-0.10.40.5-0.30.2-0.1-0.1-0.21.0
Condit. Reinf. active minus inactive responses0.60.83.81.2-0.2-2.00.3-0.20.70.3-0.40.3-0.7-1.21.3-0.2
Condit. Reinf. active-inactive response ratio0.91.13.50.2-0.7-1.90.8-0.71.00.7-0.80.7-1.2-1.41.5-0.8
Condit. Reinf. active responses0.20.21.40.1-0.5-1.20.1-0.10.50.3-0.20.2-0.5-0.60.7-0.1
Condit. Reinf. inactive responses0.30.40.8-0.70.10.7-0.70.6-0.5-0.50.6-0.40.60.9-0.90.8
Condit. Reinf. lever presses0.00.10.2-0.3-0.00.4-0.20.20.40.50.00.0-0.00.1-0.10.2
Condit. Reinf. lever reinforcers received0.20.21.20.3-0.3-1.10.1-0.10.50.3-0.20.2-0.5-0.60.80.0
Conditioned reinforcement - actives0.10.21.00.1-0.1-0.5-0.0-0.2-0.6-0.80.00.10.3-0.0-0.1-1.0
Conditioned reinforcement - inactives0.71.01.60.40.91.1-1.10.8-1.1-0.70.9-1.21.21.0-1.31.1
Conditioned locomotion0.70.92.31.30.8-0.0-1.00.7-1.4-1.51.0-1.20.60.7-0.3-0.7
Patch foraging indifference point 0 sec0.20.41.7-0.4-0.9-0.80.3-0.40.50.8-0.1-0.10.1-0.40.1-1.3
Patch foraging indifference point AUC0.30.41.1-1.1-0.20.90.7-0.70.0-0.2-0.70.6-0.90.10.5-0.1
Delay disc. indifference point, 0s delay0.60.62.81.0-0.3-1.7-0.00.10.70.5-0.1-0.1-0.7-1.01.2-0.6
Delay disc. indifference point, 16s delay0.40.51.7-1.3-1.01.20.4-0.50.50.8-0.40.3-0.30.2-0.30.2
Delay disc. indifference point, 2s delay1.11.22.80.1-1.0-1.60.8-0.81.21.0-0.90.9-1.3-1.41.7-0.7
Delay disc. indifference point, 24s delay0.30.31.0-1.0-0.70.00.3-0.40.61.0-0.40.4-0.4-0.30.1-0.6
Delay disc. indifference point, 4s delay0.40.41.11.00.1-0.30.2-0.20.91.0-0.40.1-0.9-0.61.10.2
Delay disc. indifference point, 8s delay0.70.82.41.4-0.7-0.80.1-0.10.70.3-0.10.3-1.2-0.71.5-1.4
Indifference point function ln k0.61.03.3-0.4-1.8-1.60.6-0.61.41.6-0.60.5-0.4-1.10.5-0.2
Indifference point function log k0.61.03.3-0.4-1.8-1.60.6-0.61.41.6-0.60.5-0.4-1.10.5-0.2
Patch foraging total patch changes 0 sec0.30.62.0-0.4-1.2-1.10.4-0.50.81.0-0.30.1-0.1-0.70.3-1.4
Patch foraging total patch changes 12 sec0.81.02.0-1.4-1.1-0.01.2-1.00.91.2-1.10.9-0.9-0.60.8-1.1
Patch foraging total patch changes 18 sec0.20.21.5-0.6-0.60.30.1-0.20.40.6-0.10.1-0.4-0.00.4-1.2
Patch foraging total patch changes 24 sec1.42.57.5-2.7-2.0-0.51.7-1.91.11.1-1.61.7-1.2-1.00.9-1.6
Patch foraging total patch changes 6 sec0.20.31.0-1.0-0.8-0.30.7-0.80.40.5-0.60.5-0.5-0.40.4-0.5
Patch foraging time to switch 0 sec0.51.02.20.31.41.5-0.70.9-1.2-1.10.6-0.51.11.0-1.30.4
Patch foraging water rate 0 sec1.63.36.7-1.6-2.6-2.11.5-1.82.32.4-1.51.4-1.5-1.91.5-0.8
Patch foraging water rate 12 sec0.51.01.9-0.8-1.3-1.40.8-1.21.01.0-0.80.9-0.9-1.10.80.3
Patch foraging water rate 18 sec2.74.111.1-0.4-2.6-3.31.6-1.91.91.4-1.51.5-1.9-2.42.4-1.9
Patch foraging water rate 24 sec1.92.66.50.5-1.9-2.51.4-1.51.61.4-1.21.3-1.5-2.11.8-1.4
Patch foraging water rate 6 sec1.82.65.6-1.0-2.4-1.81.3-1.81.92.0-1.31.3-1.5-1.61.4-1.0
Seeking ratio, delayed vs. immediate footshock0.30.42.5-1.6-0.7-0.10.7-0.50.30.2-0.70.8-0.2-0.3-0.20.3
Distance traveled before self-admin0.20.20.90.9-0.2-0.8-0.20.10.20.20.2-0.3-0.3-0.30.7-0.9
Distance traveled after self-admin0.91.25.40.4-1.3-1.30.3-0.60.91.1-0.30.2-1.0-0.91.4-2.3
Extensor digitorum longus weight0.41.63.6-1.9-1.0-0.71.5-1.31.51.4-1.41.3-1.4-1.21.0-0.2
Bone: elastic displacement0.20.21.1-0.10.50.1-0.20.2-0.8-1.00.3-0.30.50.3-0.40.1
Bone: elastic work0.60.71.9-0.3-0.6-1.41.0-1.00.2-0.2-0.80.8-0.9-1.01.1-0.9
Bone: endosteal estimation0.51.06.7-1.1-0.32.6-0.10.2-0.20.30.1-0.20.81.2-1.60.6
Bone: endosteal perimeter0.40.83.8-1.5-0.52.00.1-0.00.10.6-0.10.10.60.9-1.50.7
Epididymis fat weight0.20.61.81.30.8-0.5-0.80.7-0.9-1.00.9-0.60.60.7-0.2-0.5
Delta time in closed arm before/after self-admin0.70.74.4-0.70.61.20.3-0.0-0.4-0.5-0.20.20.70.4-1.12.1
Delta time in open arm before/after self-admin2.92.93.9-1.7-1.9-1.41.8-1.91.91.5-1.91.8-2.0-1.81.5-0.7
Diff in mean of infusions in LGA sessions1.31.53.61.71.00.2-1.61.5-0.8-0.61.5-1.91.51.0-1.1-0.2
Delay discount exponential model param0.30.31.0-0.40.50.2-0.30.3-0.7-0.60.3-0.40.90.5-1.00.5
Extinction: sum of active levers before priming1.01.12.4-1.4-1.10.31.5-1.60.60.6-1.41.4-0.5-0.7-0.10.1
Active lever presses in extinction session 60.90.91.91.30.81.4-0.90.9-0.7-0.20.9-1.11.11.1-1.20.2
Bone: final force1.72.73.7-1.9-1.9-1.61.9-1.91.51.3-1.71.6-1.5-1.71.3-0.9
Bone: final moment1.72.73.9-1.8-2.0-1.81.8-1.81.51.2-1.61.6-1.5-1.81.4-1.2
Food consumed during 24 hour testing period2.02.85.1-1.1-1.8-1.41.7-1.62.12.3-1.71.6-1.7-1.71.7-0.9
Glucose1.42.35.8-0.51.52.4-1.01.0-1.5-1.21.0-1.01.51.7-2.02.0
Heart weight0.40.64.40.7-1.0-0.8-0.30.40.20.20.3-0.2-0.4-0.10.9-2.1
Delay discount hyperbolic model param0.30.31.0-0.70.40.3-0.20.2-0.7-0.50.3-0.30.90.5-1.00.4
Intermittent access intake day 1-15 change1.63.46.12.32.51.3-1.51.5-2.2-2.11.5-1.82.01.3-1.81.6
Intermittent access intake escalation1.73.57.22.32.71.3-1.51.6-2.1-2.01.6-1.92.01.3-1.81.7
Intermittent access intake escalation 21.61.85.00.62.21.7-0.50.5-1.6-1.40.5-0.81.40.9-1.52.2
Intermitt. access day 1 inactive lever presses0.00.10.60.70.20.3-0.40.1-0.20.00.3-0.50.30.2-0.20.6
Intermitt. access day 15 inactive lever presses0.30.51.00.90.50.3-1.00.8-0.9-0.90.9-0.90.60.6-0.30.2
Intermitt. access escalation Index0.91.32.0-0.8-1.0-0.91.3-1.21.10.9-1.21.3-1.4-1.31.3-0.7
Intermittent access day 1 total infusions0.20.21.00.2-0.70.1-0.70.40.00.30.5-0.50.10.50.0-1.0
Intermittent access day 15 total infusions0.91.34.02.01.10.5-1.31.2-1.2-1.11.3-1.51.10.8-0.80.0
Intermittent access terminal intake (last 3 days)0.30.30.70.90.40.4-0.70.5-0.6-0.40.6-0.80.70.5-0.50.2
Intermittent access total infusions0.30.41.51.2-0.0-0.1-0.90.8-0.3-0.30.8-0.80.30.40.1-0.8
Intermittent access day 1 locomotion0.30.41.61.3-0.2-0.1-1.00.9-0.2-0.00.8-0.90.20.60.2-0.5
Intermittent access day 15 total locomotion0.81.54.22.1-0.1-0.6-1.51.3-1.0-1.01.5-1.81.00.8-0.2-1.3
Intermittent access total locomotion0.50.62.21.5-0.3-0.6-1.00.7-0.3-0.20.9-1.10.20.30.5-1.0
Intermittent access standard deviation0.50.91.91.01.41.0-0.80.8-1.2-1.30.8-0.90.80.9-0.90.4
Left kidney weight0.52.19.7-3.1-1.40.91.9-1.30.91.0-1.81.9-0.8-0.5-0.00.4
Right kidney weight0.52.211.2-3.3-1.61.31.8-1.40.81.0-1.61.7-0.7-0.0-0.2-0.2
Cocaine induced anxiety2.13.07.31.51.90.4-1.92.0-2.3-2.72.0-1.91.51.5-1.0-0.3
Post-drug Anxiety0.50.62.30.80.7-0.6-0.60.5-0.9-1.50.7-0.5-0.30.20.9-0.6
Baseline Anxiety1.72.04.6-0.6-1.3-1.21.2-1.71.41.4-1.21.3-2.0-1.42.1-0.9
Tail length3.011.726.0-4.2-5.1-1.64.1-3.83.53.2-4.13.7-2.6-2.81.4-2.3
Length with tail3.012.933.3-5.8-5.0-0.64.3-4.23.43.5-4.33.9-2.5-2.41.0-1.6
Length without tail0.92.713.4-3.7-1.60.81.5-2.01.42.1-1.71.6-0.9-0.50.1-0.5
Times rat made contact with spout1.41.64.7-1.0-1.4-0.21.4-1.31.82.2-1.51.3-1.0-1.00.60.4
Lifetime Intake0.40.51.51.10.0-0.2-0.90.8-0.5-0.70.8-0.80.20.40.1-1.2
Liver weight, left0.40.71.9-1.1-1.4-0.10.8-0.81.01.1-0.90.8-0.4-0.40.1-0.7
Liver weight, right0.50.92.5-1.3-0.60.31.1-1.11.01.6-1.20.9-0.3-0.50.00.6
Locomotor activity1.32.13.2-1.4-1.8-1.61.4-1.61.51.4-1.51.5-1.4-1.41.3-0.5
Locomotor testing distance0.50.92.7-1.1-1.0-1.60.9-0.80.60.3-0.80.8-0.8-1.01.0-0.8
Locomotor testing rearing0.20.41.0-0.9-1.0-0.80.5-0.50.50.4-0.40.4-0.6-0.50.5-0.8
Locomotion in novel chamber0.70.92.61.61.30.8-0.81.2-0.7-0.30.6-0.81.01.0-0.80.8
Locomotion in novel chamber post-restriction0.10.20.8-0.00.1-0.30.20.2-0.6-0.9-0.10.20.00.30.2-0.8
Fecal boli incidents, locomotor time 10.20.41.7-0.01.20.00.3-0.3-0.7-1.3-0.20.3-0.0-0.2-0.10.8
Change in fecal boli incidents, locomotor task2.42.44.10.91.31.9-1.91.7-1.5-0.71.8-1.61.72.0-1.60.4
Time >=10cm from walls, locomotor time 11.51.53.6-0.60.91.3-0.91.0-1.8-1.91.1-0.81.41.6-1.50.0
Bouts of movement, locomotor time 10.50.63.2-1.60.11.80.4-0.6-0.00.5-0.40.4-0.00.3-0.6-0.2
Total resting periods, locomotor time 10.50.52.9-1.70.01.60.5-0.7-0.10.3-0.40.4-0.10.2-0.4-0.6
Rest time, locomotor task time 10.40.52.10.11.41.3-0.10.3-0.8-0.90.1-0.10.30.4-0.50.0
Distance moved, locomotor task time 11.21.84.8-1.9-2.2-1.51.2-1.31.41.3-1.21.2-1.1-1.10.8-0.2
Vertical activity count, locomotor time 10.00.10.6-0.2-0.5-0.8-0.1-0.00.10.30.1-0.10.3-0.1-0.20.6
Time >=10cm from walls, locomotor time 20.20.31.3-1.1-0.5-1.00.4-0.5-0.0-0.5-0.30.4-0.4-0.40.5-0.2
Bouts of movement, locomotor time 21.01.58.73.01.00.8-1.41.3-0.5-0.11.3-1.60.70.9-0.3-0.4
Total resting periods, locomotor time 21.12.08.83.01.11.0-1.71.5-0.7-0.31.6-1.91.01.1-0.6-0.5
Rest time, locomotor task time 23.54.413.30.63.02.8-1.31.4-2.0-1.81.3-1.42.01.7-2.43.6
Distance moved, locomotor task time 24.25.09.5-2.6-3.1-2.72.0-2.21.91.5-2.02.0-2.1-2.12.1-2.6
Vertical activity count, locomotor time 20.81.13.1-1.0-1.5-1.80.8-0.70.60.1-0.70.6-0.7-0.90.9-1.7
Light reinforcement 15.713.918.7-2.6-4.3-4.04.0-4.03.93.2-3.83.7-3.9-4.13.7-2.9
Light reinforcement 22.74.28.2-0.5-2.9-2.81.8-1.72.11.3-1.71.6-2.3-2.32.4-1.8
Bone: marrow area0.51.07.0-1.2-0.32.6-0.00.1-0.10.40.1-0.20.71.2-1.60.6
Bone: maximum diameter0.71.35.8-1.5-0.12.4-0.00.0-0.10.50.1-0.21.01.2-2.01.3
Bone: maximum force0.30.61.7-1.3-1.1-0.50.9-0.90.60.5-0.70.6-0.5-0.60.4-0.9
Bone: maximum moment0.30.61.6-1.1-1.2-0.60.7-0.70.50.4-0.60.5-0.5-0.60.5-1.3
Mean time between licks in bursts1.22.95.00.22.01.8-1.41.4-2.2-2.11.4-1.41.91.9-1.81.5
Mean num. licks in bursts1.52.45.1-2.1-2.3-0.21.6-1.71.92.1-1.71.4-1.2-1.00.4-0.4
Cd content in liver0.91.02.0-1.2-1.20.11.3-1.31.00.9-1.41.4-0.8-0.80.40.0
Co content in liver1.01.22.7-1.1-1.60.71.3-1.21.31.6-1.21.1-0.7-0.50.1-0.7
Cu content in liver0.40.41.21.10.3-0.8-0.70.8-0.4-0.60.8-0.80.50.20.2-0.8
Fe content in liver0.91.11.91.10.51.2-1.31.2-1.0-0.71.0-1.10.91.4-0.9-0.7
K content in liver0.10.10.30.1-0.1-0.3-0.20.30.30.40.2-0.30.1-0.00.2-0.5
Mg content in liver0.40.42.2-0.0-0.7-0.40.4-0.41.11.5-0.40.3-0.4-0.60.5-0.7
Mn content in liver1.11.22.3-1.2-1.5-0.71.1-1.11.31.5-1.11.0-0.9-1.00.9-0.8
Na content in liver0.10.10.30.4-0.50.1-0.40.30.20.40.2-0.30.10.1-0.0-0.6
Rb content in liver3.13.66.9-2.6-2.3-0.92.3-2.22.01.9-2.12.2-1.5-1.81.0-1.1
Se content in liver0.10.10.60.20.3-0.3-0.10.10.10.3-0.0-0.00.2-0.1-0.10.8
Sr content in liver0.20.20.6-0.7-0.50.30.4-0.4-0.3-0.8-0.20.40.00.1-0.40.1
Zn content in liver0.40.40.80.70.90.2-0.50.6-0.3-0.20.7-0.80.90.4-0.80.8
Bone: minimum diameter0.61.04.6-2.0-0.72.10.5-0.40.30.9-0.50.40.40.8-1.30.6
Time in familiar zone, hab. session 10.10.10.30.10.00.5-0.00.2-0.4-0.40.1-0.30.30.4-0.5-0.4
Time in novel zone, hab. session 10.30.32.2-1.5-0.10.00.4-0.50.20.2-0.50.8-0.3-0.30.10.5
Total zone transitions, hab. session 11.92.64.41.61.70.8-2.02.0-1.5-1.42.0-2.11.81.5-1.30.4
Total locomotion distance, hab. session 12.94.28.31.62.90.7-2.32.3-2.2-1.92.4-2.42.41.7-1.71.0
Locomotion velocity, hab. session 12.02.85.41.62.30.4-1.91.9-1.7-1.42.0-2.12.01.2-1.41.1
Time in familiar zone, hab. session 20.20.20.70.8-0.5-0.50.00.10.50.7-0.2-0.20.0-0.10.0-0.5
Time in novel zone, hab. session 20.30.31.2-1.10.1-0.30.5-0.60.0-0.2-0.40.7-0.6-0.60.60.3
Total zone transitions, hab. session 20.60.81.41.10.7-1.0-1.21.2-0.6-0.71.2-1.00.90.3-0.1-0.7
Total locomotion distance, hab. session 20.91.12.71.71.6-0.9-1.21.3-0.9-1.11.2-1.11.00.2-0.10.2
Locomotion velocity, hab. session 20.81.12.31.51.5-1.0-1.11.3-1.0-1.31.2-1.11.00.2-0.1-0.0
Novel to familiar place preference ratio1.31.45.7-0.90.91.4-0.60.5-2.0-2.40.8-0.60.81.2-1.0-0.1
Novelty place preference1.51.75.9-1.20.91.7-0.60.5-2.1-2.40.7-0.61.01.4-1.3-0.1
Time in novel zone, NPP test1.41.55.3-1.10.91.5-0.60.6-2.0-2.30.8-0.60.91.3-1.2-0.1
Total zone transitions, NPP test1.31.96.32.51.3-0.9-1.71.9-0.8-0.81.7-1.71.10.6-0.1-1.1
Total locomotion distance, NPP test0.20.31.20.90.7-1.1-0.40.60.0-0.00.5-0.50.3-0.40.4-0.7
Locomotion velocity, NPP test0.20.31.30.80.5-1.1-0.20.30.10.00.2-0.20.1-0.50.5-0.8
Intraocular pressure0.10.21.2-0.1-0.3-1.1-0.30.2-0.2-0.30.3-0.30.3-0.10.3-0.9
Delta distance traveled before/after self-admin1.92.04.2-0.4-1.7-1.41.2-1.31.51.5-1.21.1-1.4-1.51.3-2.1
Delta ambulatory time before/after self-admin1.11.32.7-0.8-1.3-0.81.1-1.41.41.6-1.11.1-1.1-1.20.9-0.8
Parametrial fat weight0.10.31.3-0.20.51.1-0.2-0.1-0.30.40.2-0.20.60.7-0.70.6
Pavlov. Cond. lever latency0.60.82.3-1.5-0.31.11.0-1.10.30.4-1.01.2-0.8-0.40.40.3
Pavlov. Cond. magazine entry latency0.91.23.00.50.90.2-1.21.3-1.0-0.61.2-1.41.71.1-1.50.0
Pavlov. Cond. change in total contacts1.81.94.82.20.5-0.8-1.81.9-0.8-0.71.7-1.81.61.0-0.8-0.8
Pavlov. Cond. index score0.50.71.40.80.5-0.6-1.01.0-0.6-0.61.0-1.21.20.6-0.8-0.3
Pavlov. Cond. latency score0.30.41.00.40.3-0.6-0.70.8-0.5-0.50.7-0.91.00.5-0.7-0.3
Pavlov. Cond. lever contacts0.70.92.01.40.3-0.7-1.21.3-0.6-0.71.2-1.31.00.7-0.6-0.4
Pavlov. Cond. magazine entry number1.51.93.9-1.4-1.2-0.01.7-1.81.10.7-1.72.0-1.9-1.21.3-0.1
Pavlov. Cond. intertrial magazine entries3.03.56.0-0.5-1.7-1.71.9-1.92.32.1-1.91.9-2.4-2.22.3-0.2
Pavlov. Cond. lever-magazine prob. diff.0.81.02.11.30.7-0.5-1.21.3-0.8-0.61.2-1.51.30.8-0.9-0.4
Pavlov. Cond. response bias1.31.63.41.50.8-0.5-1.61.7-0.9-0.71.6-1.81.61.0-1.0-0.3
Pavlov. Cond. lever latency0.30.40.70.10.30.2-0.60.6-0.8-0.90.7-0.80.70.7-0.6-0.0
Pavlov. Cond. magazine entry latency0.50.61.31.20.0-1.00.6-0.50.80.9-0.60.7-0.7-1.11.1-0.1
Pavlov. Cond. change in total contacts0.20.41.31.10.2-0.50.3-0.20.50.4-0.40.5-0.7-0.61.0-0.4
Pavlov. Cond. index score0.30.40.70.70.2-0.40.5-0.50.70.8-0.50.7-0.6-0.80.80.3
Pavlov. Cond. latency score0.30.40.80.80.1-0.50.6-0.50.80.8-0.60.8-0.7-0.90.90.2
Pavlov. Cond. lever contacts0.30.40.9-0.3-0.3-0.20.7-0.70.80.8-0.71.0-0.7-0.70.7-0.1
Pavlov. Cond. magazine entry number0.40.41.1-1.0-0.41.1-0.50.3-0.4-0.10.5-0.60.51.0-1.00.0
Pavlov. Cond. intertrial magazine entries0.71.02.3-1.2-1.5-1.40.9-1.00.90.8-0.90.9-0.9-0.90.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.90.90.3-0.30.4-0.30.70.7-0.50.6-0.6-0.80.80.5
Pavlov. Cond. response bias0.10.20.40.30.1-0.30.5-0.40.40.5-0.40.6-0.4-0.60.6-0.0
Time in closed arm before self-admin0.40.53.00.50.2-1.0-0.30.40.20.40.3-0.5-0.3-0.30.9-1.7
Time in closed arm after self-admin0.91.02.61.61.30.6-0.61.2-1.2-1.40.7-0.91.00.7-0.6-0.1
Time in open arm before self-admin0.20.30.6-0.10.30.7-0.50.2-0.8-0.60.5-0.40.60.7-0.50.3
Time in open arm after self-admin3.84.29.8-3.1-2.3-0.52.1-2.62.22.5-2.22.1-1.9-1.61.10.0
Bone: periosteal estimation0.40.84.2-1.6-0.72.10.3-0.20.20.8-0.20.10.40.8-1.30.6
Bone: periosteal perimeter0.40.72.4-1.5-1.40.90.7-0.60.81.2-0.60.5-0.00.2-0.7-0.3
Bone: post-yield work0.91.43.60.10.71.9-1.31.3-0.8-0.31.2-1.21.41.6-1.60.6
Progressive ratio test 1 active lever presses0.10.10.40.2-0.50.3-0.40.50.00.20.2-0.60.10.4-0.1-0.6
Progressive ratio test 1 breakpoint0.10.10.40.2-0.50.2-0.40.50.00.10.2-0.60.10.4-0.1-0.6
Progressive ratio test 1 inactive lever presses0.20.30.50.50.10.5-0.60.6-0.6-0.20.4-0.70.70.6-0.6-0.3
Progressive ratio test 2 active lever presses0.50.52.60.8-0.8-1.2-0.70.50.30.20.4-0.4-0.1-0.20.7-1.6
Progressive ratio test 2 breakpoint0.50.62.50.8-0.9-1.3-0.70.50.30.30.4-0.3-0.2-0.30.8-1.6
Progressive ratio test 2 inactive lever presses0.61.02.11.30.20.5-1.51.4-0.9-0.61.2-1.21.30.9-1.1-0.2
Incentive Sensitization - Responses1.11.66.70.5-1.5-2.6-0.1-0.31.00.9-0.10.6-0.9-1.21.8-2.1
Incentive Sensitization - Breakpoint1.41.87.50.5-1.6-2.7-0.1-0.31.10.9-0.20.6-1.0-1.31.9-2.1
Sum of active levers in priming session hrs 5-60.70.65.42.30.21.1-0.40.60.10.30.2-0.30.20.5-0.3-0.2
Progressive ratio0.50.84.10.4-0.9-1.70.1-0.30.50.3-0.10.3-0.6-0.70.9-2.0
Food seeking constrained by brief footshock0.30.42.90.30.1-1.7-0.20.30.20.20.3-0.4-0.3-0.51.1-0.7
Seeking ratio, punishment vs. effort0.10.10.9-0.80.30.10.1-0.00.10.4-0.1-0.20.0-0.00.10.9
Retroperitoneal fat weight0.52.04.00.71.5-0.5-1.41.1-1.7-1.61.6-1.62.01.1-1.41.1
Reaction time number correct0.40.72.50.71.1-1.6-0.80.7-0.9-1.20.8-0.60.6-0.10.1-0.2
Reaction time mean minus median0.82.13.60.91.20.7-1.81.9-1.5-1.51.7-1.81.61.6-1.2-0.7
Reaction time mean minus median AUC0.82.03.61.21.20.4-1.71.9-1.5-1.61.6-1.71.41.3-0.9-1.1
Reaction time num false alarms0.50.73.81.30.3-2.0-0.40.30.20.10.4-0.6-0.4-0.81.3-0.9
Reaction time num false alarms AUC0.61.04.61.50.3-2.2-0.50.40.20.00.4-0.7-0.4-0.81.4-1.2
Reaction time trials correct on left0.40.72.50.71.1-1.6-0.80.7-0.9-1.20.8-0.60.6-0.10.1-0.2
Reaction time trials on left0.50.92.30.91.3-1.5-1.00.8-1.0-1.31.0-0.80.80.1-0.0-0.2
Reaction time mean1.11.83.61.80.70.6-1.91.8-1.0-0.71.9-1.70.91.4-0.4-1.4
Reaction time mean AUC1.42.34.32.01.00.8-2.11.9-1.2-0.92.0-1.91.11.6-0.6-1.3
Median of all reaction times1.01.43.82.00.50.5-1.71.4-0.7-0.41.7-1.50.51.1-0.1-1.3
Reaction time omissions5.37.713.72.82.61.6-3.73.5-2.4-1.73.6-3.52.83.1-2.30.5
Reaction time false alarm rate0.50.72.11.0-0.4-1.30.1-0.10.70.7-0.2-0.2-0.9-0.91.4-1.0
Reaction time premature initiation rate0.81.13.2-1.10.11.6-0.60.6-0.70.10.5-0.71.61.3-1.80.9
Reaction time premature initiations0.61.13.3-0.60.70.6-0.90.9-1.1-0.60.9-0.91.81.1-1.70.9
Std. dev. reaction times1.63.05.61.71.40.6-2.32.4-1.7-1.52.2-2.21.61.8-1.0-1.0
Reaction time trials completed0.50.92.30.91.3-1.5-1.00.8-1.0-1.31.0-0.80.80.1-0.0-0.2
Reaction time trials AUC0.40.82.50.81.2-1.6-0.90.8-1.0-1.30.9-0.70.70.00.0-0.0
Run reversals in cocaine runway, females0.60.61.2-1.0-0.9-0.11.0-1.00.50.2-0.91.1-0.8-0.80.4-0.8
Run reversals in cocaine runway, males0.20.21.4-0.40.1-1.2-0.40.40.2-0.00.3-0.40.2-0.10.10.1
Latency to leave start box in cocaine runway1.21.38.83.00.90.5-1.21.0-0.5-0.01.2-1.40.80.8-0.5-0.3
Latency to leave start box in cocaine runway, F0.10.11.21.1-0.0-0.0-0.10.00.20.50.1-0.40.10.1-0.1-0.4
Latency to leave start box in cocaine runway, M3.02.89.73.11.91.5-1.71.7-1.4-0.91.7-1.81.41.5-1.00.6
Std. dev. time between licks in bursts1.21.73.91.12.01.3-1.21.1-1.7-1.51.3-1.21.21.3-1.00.4
Total sessions with >9 infusions0.20.32.30.6-0.3-0.1-0.10.4-0.2-0.50.0-0.3-0.10.20.3-1.5
Short access day 1 total inactive lever presses0.50.64.12.00.1-0.2-0.50.7-0.6-0.70.5-0.40.60.2-0.2-1.3
Short access day 10 total inactive lever presses0.20.42.41.50.8-0.2-0.60.4-0.5-0.60.6-0.40.4-0.10.00.5
Short access day 1 total infusions0.30.31.2-1.1-0.7-0.10.6-0.30.2-0.1-0.70.6-0.6-0.20.4-0.9
Short access day 10 total infusions0.50.61.30.0-0.20.8-1.10.9-0.6-0.41.0-1.10.61.1-0.7-0.5
Short access total infusions0.40.52.00.50.10.3-0.90.8-0.8-1.00.8-0.70.30.7-0.2-1.4
Short access day 1 locomotion0.70.92.41.50.90.8-0.80.9-1.1-1.10.7-0.81.00.9-0.9-0.5
Short access day 10 total locomotion0.30.51.00.70.00.3-0.80.7-0.8-0.50.8-1.00.51.0-0.2-1.0
Short access total locomotion0.60.73.81.3-0.1-0.2-0.50.6-0.7-0.80.5-0.80.30.50.1-2.0
One hour access (0.3 mA shock)0.30.30.70.2-0.7-0.80.5-0.60.3-0.1-0.50.5-0.6-0.70.7-0.8
Compulsive drug intake1.51.82.7-0.5-1.1-1.01.4-1.31.51.2-1.51.7-1.6-1.41.5-1.3
One hour access (shock baseline)0.20.30.80.9-0.1-0.4-0.50.3-0.7-0.80.6-0.70.50.2-0.4-0.7
Social response proportion0.10.10.70.2-0.20.9-0.30.1-0.10.10.3-0.5-0.00.5-0.40.3
Social responses0.10.20.60.10.1-0.70.5-0.80.30.1-0.30.2-0.6-0.60.40.2
Social time0.30.41.7-1.3-0.20.70.5-0.80.30.6-0.50.5-0.9-0.10.4-0.9
Soleus weight3.19.014.8-2.7-3.3-2.33.1-3.03.73.8-3.23.1-2.9-3.12.5-1.5
Bone: stiffness0.10.20.70.1-0.1-0.1-0.30.4-0.4-0.40.5-0.50.50.4-0.4-0.9
Tibialis anterior weight2.79.211.0-2.3-3.1-3.33.2-3.03.23.0-3.13.0-3.2-3.33.1-2.6
Time to tail flick, vehicle, before self-admin0.50.51.50.71.2-0.0-0.70.6-1.0-0.70.8-0.90.80.6-0.4-0.1
Time to tail flick, vehicle, after self-admin1.82.45.40.92.30.8-1.41.4-1.8-1.91.4-1.51.91.2-1.61.7
Time to tail flick, test, before self-admin0.80.82.00.11.4-0.1-0.60.7-1.1-1.10.7-1.01.10.5-1.21.1
Time to tail flick, test, after self-admin0.50.54.0-0.21.40.7-0.1-0.1-0.4-0.10.1-0.10.30.1-0.52.0
Delta time to tail flick, vehicle, before/after SA0.30.32.9-0.10.30.1-0.00.10.1-0.2-0.10.00.2-0.1-0.31.7
Delta time to tail flick, test, before/after SA0.20.20.5-0.40.00.20.3-0.50.40.6-0.40.7-0.6-0.30.60.3
Tibia length0.30.92.4-1.2-1.2-0.71.0-1.0-0.0-0.7-0.81.2-0.7-0.50.3-1.6
Ambulatory time before self-admin0.30.41.81.1-0.2-0.9-0.20.20.0-0.20.2-0.3-0.4-0.30.9-1.3
Ambulatory time after self-admin1.61.85.6-0.1-1.3-1.80.7-1.01.31.4-0.80.6-1.3-1.51.8-2.4
Bone: tissue strength0.30.32.2-0.2-0.4-1.50.1-0.10.40.3-0.10.0-0.2-0.80.8-0.2
Total heroin consumption0.91.01.91.30.40.9-1.41.2-0.40.41.2-1.31.21.1-1.2-0.2
Bone: trabecular number0.10.22.1-0.2-0.7-0.5-0.20.20.20.10.1-0.2-0.0-0.00.3-1.4
Bone: trabecular spacing2.12.84.2-0.7-1.1-1.82.0-2.01.51.2-1.91.9-1.9-2.01.9-0.7
Bone: trabecular thickness0.81.01.7-0.10.21.0-1.31.2-1.0-1.01.2-1.21.01.3-1.1-0.4
Bone: trabecular tissue density0.40.72.8-1.7-0.00.50.9-0.90.60.6-0.90.9-0.8-0.2-0.00.8
Water consumed over 24 hours1.92.65.9-0.9-2.0-1.61.4-1.42.32.4-1.61.4-1.3-1.81.2-0.2
Number of responses in last shaping day0.10.10.6-0.6-0.80.20.2-0.10.20.0-0.40.30.10.1-0.4-0.6