Syngr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA NM_019166.2 0.04 0.03 5.5e-04 0.03 0.01 0 0.01 5.8e-04 4.3e-02 8.6e-02 2.1e-02
2 pVTA intron excision ratio chr7_113535139_113539266 0.08 0.04 7.9e-07 0.08 0.08 0.08 0.06 5.9e-07 1.0e-06 5.4e-07 8.7e-06
3 pVTA intron excision ratio chr7_113535139_113536500 0.09 0.04 1.9e-07 0.08 0.09 0.09 0.09 3.7e-07 1.0e-07 6.4e-08 1.3e-07
4 Brain alternative polyA XM_006241971.4 0.06 0.03 4.1e-06 0.04 0.05 0.01 0.04 5.2e-05 1.5e-05 3.1e-02 6.3e-05
5 Brain alternative polyA NM_019166.2 0.06 0.03 1.7e-05 0.04 0.04 0 0.04 1.9e-04 4.8e-05 1.4e-01 2.6e-04
6 RMTg gene expression Syngr1 0.17 0.09 1.0e-03 0.05 0.09 0.05 0.03 1.9e-02 2.8e-03 1.5e-02 6.3e-02
7 NAcc intron excision ratio chr7_113535139_113539266 0.08 0.04 4.3e-10 0.06 0.06 0.06 0.06 5.9e-10 4.0e-09 2.4e-09 8.5e-09
8 Liver mRNA stability Syngr1 0.65 0.1 0.0e+00 0.31 0.5 0.49 0.49 4.2e-35 6.3e-63 2.5e-61 9.0e-62
9 IC gene expression Syngr1 0.08 0.05 3.3e-03 0.05 0.05 0.04 0.05 4.5e-03 2.8e-03 7.9e-03 4.8e-03
10 NAcc intron excision ratio chr7_113535139_113536500 0.09 0.04 1.9e-11 0.07 0.07 0.07 0.07 5.5e-11 2.8e-10 1.2e-10 1.6e-10
11 BLA gene expression Syngr1 0.07 0.05 9.2e-03 0.01 0.02 0.02 0.01 7.0e-02 4.7e-02 3.0e-02 7.0e-02
12 Adipose gene expression Syngr1 0.14 0.07 2.0e-10 0.06 0.07 0.07 0.06 7.9e-07 3.1e-08 5.2e-08 3.6e-07
13 pVTA gene expression Syngr1 0.12 0.07 2.1e-05 0.06 0.03 0.06 0.04 1.1e-05 9.8e-04 8.8e-06 3.0e-04
14 Brain isoform ratio NM_019166.2 0.04 0.02 7.5e-04 0.03 0.03 0.01 0.03 4.9e-04 9.9e-04 5.8e-02 6.1e-04
15 Brain isoform ratio XM_006241971.4 0.03 0.02 2.6e-03 0.03 0.02 0.01 0.02 9.8e-04 3.0e-03 4.5e-02 2.2e-03
16 PL gene expression Syngr1 0.12 0.06 2.3e-09 0.08 0.07 0.1 0.1 1.1e-08 2.4e-08 1.3e-10 8.1e-11
17 Liver gene expression Syngr1 0.26 0.09 0.0e+00 0.16 0.22 0.21 0.21 7.6e-18 2.2e-24 4.8e-23 6.5e-23
18 LHb gene expression Syngr1 0.23 0.14 4.5e-03 0.17 0.11 0.11 0.12 7.0e-05 1.4e-03 1.7e-03 8.4e-04
19 Brain mRNA stability Syngr1 0.04 0.02 7.8e-03 0.01 0.02 0.01 0.01 5.3e-02 5.5e-03 1.6e-02 2.9e-02
20 PL mRNA stability Syngr1 0.09 0.05 3.3e-05 0.01 0.03 0.04 0.04 4.1e-02 1.7e-04 1.4e-05 8.0e-05
21 Brain gene expression Syngr1 0.34 0.1 0.0e+00 0.12 0.23 0.24 0.24 3.3e-11 1.9e-21 3.4e-22 6.1e-22
22 OFC gene expression Syngr1 0.34 0.14 1.2e-03 0.03 0.1 0.1 0.09 6.9e-02 2.4e-03 2.9e-03 3.9e-03
23 NAcc gene expression Syngr1 0.05 0.03 1.9e-04 0.01 0.03 0.02 0.02 1.1e-02 7.1e-05 1.0e-04 5.5e-04
24 Liver intron excision ratio chr7_113535139_113536500 0.08 0.05 8.3e-05 0.03 0.02 0.03 0.03 9.9e-05 3.0e-03 5.1e-04 5.5e-04
25 Liver isoform ratio NM_019166.2 0.15 0.08 6.7e-08 0.06 0.07 0.06 0.07 2.7e-07 7.4e-08 2.7e-07 4.1e-08
26 Liver isoform ratio XM_006241971.4 0.15 0.07 1.3e-08 0.07 0.07 0.07 0.08 5.4e-08 2.1e-08 4.3e-08 7.2e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.20.41.1-0.0-0.60.6-0.20.20.1-1.0-0.10.60.80.50.40.20.7-0.70.8-0.3-0.1-0.5-0.71.10.80.60.8-0.80.8
Area under the delay curve1.21.43.11.8-1.71.7-1.21.1-0.0-1.40.61.80.91.10.41.21.7-1.71.41.0-0.6-0.6-0.70.4-0.8-1.0-1.01.2-1.2
BMI with tail0.51.63.7-1.91.7-1.81.6-1.5-0.71.1-1.2-1.6-1.2-1.4-0.5-1.7-0.70.7-1.1-1.50.60.10.50.00.51.31.5-1.51.5
BMI without tail0.20.72.8-0.80.4-0.50.5-0.30.30.1-0.4-0.40.40.10.4-1.1-0.10.10.3-1.00.7-0.1-0.50.81.61.71.5-1.61.6
Body weight1.14.814.1-3.22.9-3.02.8-2.6-1.72.3-2.2-2.8-2.3-2.6-2.2-3.8-2.92.9-1.9-2.1-0.30.21.4-1.5-0.10.10.8-0.70.7
Weight adjusted by age0.30.51.50.3-0.10.0-0.50.60.80.10.9-0.40.3-0.10.1-0.7-0.50.5-0.51.00.91.21.0-0.8-0.2-0.6-1.20.9-1.0
Bone surface0.10.20.60.2-0.40.6-0.30.3-0.2-0.60.10.60.50.3-0.3-0.10.1-0.10.50.4-0.4-0.20.10.0-0.2-0.8-0.50.6-0.6
Bone volume0.00.00.30.1-0.20.2-0.10.1-0.1-0.6-0.00.30.30.0-0.1-0.30.4-0.40.30.1-0.1-0.10.00.40.0-0.10.1-0.10.1
Breakpoint value in progressive ratio session0.10.20.5-0.40.3-0.30.5-0.5-0.60.5-0.60.1-0.3-0.0-0.30.1-0.20.20.2-0.7-0.1-0.7-0.40.10.10.20.6-0.40.4
Number of licking bursts0.61.02.31.4-1.31.2-1.51.50.9-1.21.21.21.31.30.80.70.9-0.90.91.40.90.3-0.30.1-0.1-0.4-1.10.9-0.9
Context. condit. distance diff. score3.64.412.0-2.62.8-3.02.2-2.0-0.62.4-1.0-3.5-2.6-2.9-1.3-3.3-2.42.4-3.0-1.01.01.62.4-1.6-0.60.40.4-0.60.6
Locomotion velocity, session 10.91.04.40.30.10.10.0-0.1-0.90.7-0.40.3-0.2-0.2-1.2-0.9-0.70.70.40.4-1.4-0.40.7-1.5-1.3-2.1-1.62.0-2.0
Locomotion distance, session 12.43.08.32.9-2.32.5-2.22.00.7-1.71.52.31.91.70.71.11.7-1.71.72.0-0.5-0.0-0.20.0-1.0-1.6-2.02.3-2.4
Locomotion velocity, session 20.20.20.7-0.60.5-0.40.6-0.6-0.80.6-0.6-0.2-0.7-0.6-0.7-0.3-0.20.2-0.3-0.4-0.7-0.40.2-0.4-0.6-0.40.00.2-0.2
Locomotion distance, session 22.23.08.52.6-2.42.7-1.61.4-0.1-1.90.52.91.92.10.52.02.0-2.02.60.8-1.6-1.6-1.50.9-0.3-1.2-0.91.3-1.2
Locomotion velocity, session 31.21.35.0-0.00.9-1.0-0.00.20.80.90.9-1.7-1.1-1.2-0.2-1.4-0.90.9-1.91.21.62.22.0-1.2-0.7-0.5-1.10.7-0.8
Locomotion distance, session 32.22.47.82.0-1.21.0-2.12.12.0-0.92.50.10.80.61.30.10.6-0.6-0.62.82.32.51.3-0.5-0.7-0.6-2.11.5-1.6
Stereotopy head waving bouts, day 31.11.32.8-1.61.3-1.11.5-1.5-1.71.4-1.7-0.5-1.1-1.0-1.6-1.1-1.11.10.0-1.4-1.5-1.10.1-0.8-0.4-0.70.40.10.0
Stereotopy head waving duration, day 33.23.88.1-2.82.6-2.42.7-2.7-2.42.5-2.6-1.6-2.3-2.0-2.4-2.0-2.12.1-0.8-2.3-1.8-1.20.4-1.3-0.5-0.51.0-0.40.5
Locomotion velocity, session 70.91.02.7-1.31.5-1.50.6-0.6-0.31.7-0.1-1.1-1.1-1.1-0.7-0.6-1.21.2-1.50.20.30.71.1-1.3-0.9-0.5-0.40.5-0.5
Locomotion distance, session 70.40.51.6-0.50.5-0.40.2-0.3-0.70.7-0.30.0-0.4-0.3-0.8-0.4-0.80.80.00.1-0.6-0.20.6-1.0-1.0-1.3-0.91.1-1.1
Stereotopy head waving bouts, day 72.02.26.1-2.02.1-2.21.3-1.2-0.31.8-0.4-2.4-1.9-2.0-1.0-1.7-1.71.7-2.5-0.20.91.41.8-1.3-0.40.10.1-0.40.4
Stereotopy head waving duration, day 71.62.05.7-2.21.9-2.11.4-1.3-0.11.5-0.5-2.3-1.8-1.8-0.5-1.0-1.11.1-2.4-0.71.21.21.0-0.50.31.11.1-1.51.4
Locomotion velocity, session 81.92.35.2-2.01.8-1.91.7-1.7-1.61.5-1.5-1.4-1.7-1.6-1.9-2.0-2.32.3-1.1-1.1-1.1-0.21.0-1.7-1.0-1.1-0.40.6-0.6
Locomotion distance, session 80.20.31.4-0.40.5-0.50.5-0.50.10.2-0.1-1.1-0.5-0.9-0.0-1.2-0.30.3-0.9-0.20.30.70.80.0-0.10.40.3-0.40.4
Degree of sensitization distance3.43.59.3-2.92.0-1.92.7-2.7-2.51.9-2.9-0.8-1.6-1.2-2.0-0.7-1.71.70.0-3.0-2.4-2.3-0.6-0.30.20.11.8-1.11.2
Degree of sensitization stereotypy1.31.55.1-1.41.6-1.71.0-0.90.01.3-0.1-2.1-1.5-1.6-0.5-1.3-1.21.2-2.2-0.11.11.51.6-0.9-0.30.30.1-0.50.4
Conditioned locomotion0.30.30.6-0.80.7-0.80.6-0.6-0.30.8-0.4-0.8-0.8-0.7-0.5-0.7-0.70.7-0.6-0.40.00.20.7-0.5-0.2-0.20.10.0-0.0
Cocaine response after cond. corrected0.30.30.9-0.20.3-0.20.7-0.7-0.90.6-0.8-0.1-0.8-0.4-0.9-0.5-0.20.20.2-0.6-0.8-0.70.4-0.4-0.5-0.8-0.10.4-0.4
Cocaine response after cond. not corrected0.10.10.3-0.10.2-0.00.5-0.5-0.60.3-0.6-0.0-0.4-0.2-0.4-0.00.1-0.10.2-0.6-0.5-0.60.20.1-0.0-0.20.3-0.10.1
Cocaine response before conditioning0.50.61.50.2-0.40.4-0.70.81.1-0.50.90.20.80.61.21.00.9-0.9-0.30.51.00.6-0.30.90.81.20.6-0.80.8
Saline control response0.20.31.1-0.50.1-0.2-0.30.41.00.10.7-0.60.20.10.60.4-0.10.1-0.70.30.80.90.60.30.90.70.3-0.50.4
Bone: connectivity density0.10.10.4-0.6-0.00.10.2-0.2-0.2-0.3-0.30.10.40.1-0.3-0.4-0.30.30.3-0.3-0.5-0.4-0.10.20.3-0.10.3-0.10.1
Bone: cortical apparent density1.01.44.41.0-1.00.8-1.61.71.9-1.12.00.00.60.71.30.70.7-0.7-0.52.02.12.00.3-0.10.30.3-1.00.5-0.6
Bone: cortical area0.81.33.8-1.11.3-1.21.7-1.7-1.91.0-1.8-0.6-1.3-1.2-1.6-1.1-0.60.6-0.2-1.5-1.5-1.20.1-0.5-0.8-0.60.4-0.10.1
Bone: cortical porosity1.21.33.7-1.91.3-1.21.5-1.5-1.01.2-1.4-0.7-0.6-0.7-0.70.1-0.60.6-0.5-1.8-0.7-1.1-0.30.50.50.71.8-1.61.6
Bone: cortical porosity2.42.66.4-2.52.0-1.92.3-2.4-1.92.1-2.2-1.1-1.5-1.4-1.7-0.6-1.41.4-0.8-2.3-1.4-1.50.2-0.3-0.10.01.6-1.21.3
Bone: cortical thickness0.10.20.80.00.2-0.10.4-0.5-0.9-0.2-0.70.2-0.2-0.3-0.4-0.10.6-0.60.3-0.5-0.7-0.7-0.30.2-0.6-0.3-0.00.1-0.1
Bone: cortical thickness0.50.61.81.3-0.30.50.0-0.2-1.1-0.3-0.60.8-0.10.1-0.6-0.20.9-0.90.9-0.2-1.2-1.0-0.2-0.2-1.1-1.0-0.81.0-1.0
Bone: cortical tissue density0.91.34.00.9-0.90.7-1.51.61.8-1.02.0-0.00.50.71.20.60.5-0.5-0.51.92.01.90.4-0.20.20.1-1.10.6-0.7
Condit. Reinf. active minus inactive responses0.10.10.50.5-0.30.4-0.50.50.2-0.00.40.40.20.4-0.00.40.3-0.30.20.50.30.2-0.0-0.2-0.1-0.5-0.60.7-0.7
Condit. Reinf. active-inactive response ratio0.30.30.9-0.10.5-0.5-0.00.10.20.60.4-0.7-0.5-0.5-0.2-0.4-0.20.2-0.80.60.90.90.7-0.6-0.5-0.4-0.60.5-0.6
Condit. Reinf. active responses1.01.22.51.4-1.41.4-1.31.31.2-1.11.11.11.11.51.11.61.2-1.20.80.80.80.2-1.01.01.20.70.2-0.40.3
Condit. Reinf. inactive responses2.02.44.81.7-2.01.9-1.61.71.7-1.81.41.51.72.11.92.21.5-1.51.10.70.80.1-1.61.82.01.50.8-1.21.1
Incentive salience index mean0.20.30.80.9-0.70.7-0.70.80.4-0.50.50.70.70.70.40.70.6-0.60.60.60.30.1-0.40.30.3-0.2-0.30.3-0.3
Condit. Reinf. lever presses0.30.50.80.9-0.80.8-0.80.80.6-0.70.60.80.90.90.70.90.7-0.70.70.40.3-0.0-0.60.80.70.40.2-0.40.4
Condit. Reinf. active minus inactive responses0.70.83.40.8-0.20.40.0-0.1-1.10.5-0.50.8-0.10.1-1.1-0.2-0.30.30.70.2-1.4-0.9-0.0-1.1-1.3-1.8-1.31.8-1.7
Condit. Reinf. active-inactive response ratio0.60.72.20.20.3-0.10.6-0.7-1.50.7-1.00.3-0.6-0.3-1.4-0.5-0.60.60.4-0.5-1.4-1.10.1-1.0-1.0-1.5-0.71.1-1.0
Condit. Reinf. active responses0.91.34.30.10.6-0.40.5-0.7-1.41.3-0.70.1-0.9-0.7-1.6-0.7-0.90.9-0.10.1-1.4-0.60.5-1.6-1.8-2.1-1.51.9-1.9
Condit. Reinf. inactive responses0.70.93.0-0.30.8-0.70.3-0.4-0.81.1-0.2-0.4-1.0-0.9-1.0-0.6-0.70.7-0.70.4-0.60.20.9-1.4-1.7-1.5-1.41.5-1.5
Condit. Reinf. lever presses0.30.41.31.0-0.80.8-0.50.50.1-0.60.21.00.80.80.40.60.4-0.40.90.1-0.2-0.6-1.10.50.30.1-0.00.1-0.1
Condit. Reinf. lever reinforcers received0.70.93.20.00.5-0.30.5-0.7-1.41.1-0.80.2-0.7-0.5-1.4-0.4-0.80.80.1-0.2-1.5-0.80.2-1.3-1.4-1.8-1.11.5-1.4
Conditioned reinforcement - actives0.71.25.01.3-0.30.6-0.40.2-0.80.2-0.00.7-0.2-0.1-0.7-0.30.3-0.30.60.8-1.2-0.30.9-1.2-2.0-2.0-2.22.2-2.2
Conditioned reinforcement - inactives0.91.35.91.3-1.21.3-0.70.5-0.9-1.0-0.52.11.01.4-0.20.40.7-0.72.4-0.1-1.6-1.8-1.10.0-0.5-1.0-0.91.2-1.1
Conditioned locomotion0.81.04.7-0.10.5-0.11.1-1.2-2.00.8-1.70.5-0.7-0.4-1.4-0.50.0-0.00.8-1.3-2.2-1.9-0.2-0.4-0.9-1.00.00.5-0.4
Patch foraging indifference point 0 sec0.40.83.0-0.3-0.70.70.00.00.1-0.7-0.40.80.81.00.30.90.4-0.41.1-0.9-0.6-1.1-1.71.11.60.81.2-1.01.1
Patch foraging indifference point AUC1.42.06.31.8-1.41.4-1.61.50.2-1.01.01.61.01.10.00.40.8-0.81.31.8-0.20.10.3-0.8-1.5-2.1-2.52.5-2.4
Delay disc. indifference point, 0s delay0.60.72.3-0.70.6-0.61.2-1.2-1.10.4-1.3-0.2-0.6-0.4-0.60.20.0-0.00.1-1.5-0.4-1.2-0.70.60.40.51.4-1.11.2
Delay disc. indifference point, 16s delay1.81.94.52.1-2.02.1-1.71.50.4-1.71.02.01.31.50.71.51.7-1.71.61.3-0.5-0.4-0.70.4-0.6-1.0-1.31.3-1.3
Delay disc. indifference point, 2s delay0.91.04.11.8-1.01.2-0.70.6-0.4-0.60.31.30.20.40.31.32.0-2.00.90.6-0.7-0.6-0.40.6-1.2-0.6-0.50.8-0.7
Delay disc. indifference point, 24s delay1.31.56.90.7-0.90.8-0.90.8-0.3-0.80.50.90.40.6-0.7-0.3-0.00.00.81.3-0.10.10.5-1.2-1.5-2.3-2.52.6-2.6
Delay disc. indifference point, 4s delay0.60.61.71.3-1.11.1-0.60.4-0.4-0.80.01.20.50.70.00.71.2-1.21.10.3-0.4-0.8-0.60.4-0.5-0.6-0.30.6-0.5
Delay disc. indifference point, 8s delay1.31.53.41.6-1.81.8-1.51.30.4-1.70.81.81.41.30.70.91.5-1.51.71.0-0.6-0.4-0.80.6-0.4-0.7-0.91.0-1.0
Indifference point function ln k1.01.85.0-1.91.7-1.81.6-1.4-0.21.4-0.7-2.2-1.5-1.7-0.4-1.2-1.31.3-2.0-1.10.50.70.6-0.10.61.21.4-1.51.5
Indifference point function log k1.01.85.0-1.91.7-1.81.6-1.4-0.21.4-0.7-2.2-1.5-1.7-0.4-1.2-1.31.3-2.0-1.10.50.70.6-0.10.61.21.4-1.51.5
Patch foraging total patch changes 0 sec0.61.23.90.1-1.11.0-0.30.40.3-1.1-0.11.11.21.30.71.21.0-1.01.3-0.7-0.4-1.1-2.01.51.71.01.3-1.21.2
Patch foraging total patch changes 12 sec0.20.21.1-0.1-0.10.30.1-0.2-0.60.1-0.40.6-0.10.3-0.50.80.2-0.20.4-0.2-1.0-0.8-0.3-0.0-0.3-0.8-0.20.4-0.4
Patch foraging total patch changes 18 sec0.50.83.80.0-0.60.70.0-0.1-1.0-0.4-0.91.60.71.0-0.60.50.2-0.21.9-0.8-1.6-2.0-1.40.30.2-0.60.20.4-0.3
Patch foraging total patch changes 24 sec0.20.41.40.2-0.70.8-0.80.70.2-0.60.41.20.91.00.40.90.7-0.71.10.4-0.2-0.5-0.70.40.1-0.2-0.20.4-0.4
Patch foraging total patch changes 6 sec0.81.24.80.6-1.31.3-0.70.6-0.4-1.1-0.42.01.41.7-0.01.31.0-1.02.2-0.3-1.3-1.6-1.60.60.5-0.6-0.20.6-0.5
Patch foraging time to switch 0 sec0.40.83.2-1.10.7-0.61.0-1.0-0.70.9-1.0-0.1-0.5-0.4-0.20.50.0-0.0-0.2-1.3-0.7-1.0-0.40.70.50.91.8-1.51.5
Patch foraging water rate 0 sec0.10.20.80.4-0.60.5-0.20.30.2-0.9-0.10.50.80.80.1-0.1-0.20.20.9-0.2-0.2-0.4-0.60.30.80.0-0.10.2-0.2
Patch foraging water rate 12 sec0.40.82.10.4-0.80.7-0.60.71.1-1.20.70.31.01.01.11.30.7-0.70.20.10.90.3-1.21.21.51.30.8-1.11.0
Patch foraging water rate 18 sec0.40.62.00.8-1.00.9-0.80.80.7-1.30.40.91.31.40.51.00.1-0.10.90.20.3-0.2-0.90.51.20.1-0.10.1-0.1
Patch foraging water rate 24 sec0.40.51.4-1.00.6-0.80.8-0.60.10.5-0.5-0.9-0.3-0.4-0.3-0.5-1.21.2-0.6-0.80.40.2-0.2-0.01.10.60.8-1.01.0
Patch foraging water rate 6 sec0.71.13.60.9-1.00.9-1.41.51.9-1.01.60.31.41.11.41.00.3-0.3-0.11.21.41.2-0.30.61.20.7-0.2-0.20.1
Seeking ratio, delayed vs. immediate footshock0.60.71.31.0-1.00.9-0.91.00.9-1.20.80.80.81.01.10.91.1-1.10.70.50.80.2-0.81.00.80.90.4-0.50.5
Distance traveled before self-admin0.50.71.60.9-0.80.9-0.30.1-0.3-0.7-0.21.20.60.50.50.91.2-1.21.2-0.5-0.8-1.3-1.11.20.20.51.0-0.70.8
Distance traveled after self-admin0.70.84.0-0.0-0.60.70.3-0.4-0.9-0.4-1.11.30.51.0-0.50.4-0.50.51.7-1.2-1.6-2.0-1.40.30.8-0.30.6-0.20.3
Extensor digitorum longus weight0.83.27.91.8-1.91.8-1.41.41.4-2.61.01.42.41.32.21.02.8-2.81.70.30.6-0.2-1.42.81.52.01.4-1.71.7
Bone: elastic displacement0.10.10.4-0.40.4-0.40.2-0.2-0.00.3-0.1-0.4-0.1-0.3-0.3-0.6-0.60.6-0.3-0.1-0.10.20.2-0.3-0.1-0.3-0.20.1-0.1
Bone: elastic work1.62.15.1-1.61.8-1.62.2-2.2-2.21.5-2.3-1.0-1.4-1.6-1.9-1.5-1.11.1-0.4-2.1-1.7-1.30.3-0.5-0.5-0.60.8-0.40.5
Bone: endosteal estimation0.81.83.8-1.61.5-1.31.8-1.8-1.91.5-1.9-0.7-1.4-1.1-1.9-0.9-1.61.6-0.4-1.6-1.7-1.20.4-0.9-0.5-0.90.40.00.1
Bone: endosteal perimeter1.22.65.1-2.12.3-2.02.2-2.2-1.92.1-1.9-1.6-1.9-1.8-2.0-1.6-1.81.8-1.2-1.6-1.2-0.71.1-1.1-0.7-0.60.6-0.20.3
Epididymis fat weight2.48.316.7-3.94.1-4.13.6-3.5-2.33.5-2.5-3.9-3.8-3.9-2.8-3.4-3.33.3-3.6-2.1-0.40.52.6-2.2-1.2-0.30.7-0.60.6
Delta time in closed arm before/after self-admin0.40.41.50.40.3-0.10.1-0.2-0.70.6-0.30.1-0.6-0.5-0.6-0.20.2-0.20.00.2-0.8-0.20.6-0.7-1.2-1.1-1.01.1-1.1
Delta time in open arm before/after self-admin0.20.20.50.6-0.60.6-0.40.40.4-0.70.30.50.60.60.50.30.3-0.30.50.10.1-0.2-0.50.40.50.30.2-0.20.2
Diff in mean of infusions in LGA sessions0.50.61.6-0.30.6-0.60.5-0.6-1.00.8-0.7-0.2-0.7-0.5-1.2-1.3-1.01.0-0.0-0.1-0.3-0.30.6-1.2-0.9-1.2-0.91.1-1.1
Delay discount exponential model param1.31.53.3-1.81.8-1.81.3-1.2-0.11.5-0.7-1.8-0.9-1.1-0.5-1.2-1.71.7-1.5-1.10.50.50.7-0.40.81.01.0-1.21.2
Extinction: sum of active levers before priming0.70.82.60.00.9-0.60.9-1.0-1.61.2-1.1-0.1-1.2-0.5-1.30.0-0.60.6-0.5-0.5-0.5-0.80.5-1.2-1.5-1.1-0.60.9-0.8
Active lever presses in extinction session 60.30.30.6-0.50.6-0.50.7-0.7-0.70.7-0.7-0.3-0.7-0.2-0.6-0.3-0.60.6-0.2-0.60.6-0.40.1-0.6-0.3-0.10.20.00.0
Bone: final force1.11.85.6-1.01.3-1.11.8-1.9-2.41.0-2.2-0.5-1.3-1.4-2.0-1.4-0.70.7-0.0-1.7-2.2-1.50.1-0.5-1.0-1.10.30.2-0.1
Bone: final moment1.21.96.2-1.01.4-1.21.9-2.0-2.50.9-2.3-0.4-1.3-1.3-2.1-1.5-0.80.80.1-1.8-2.3-1.70.1-0.6-1.0-1.20.30.2-0.1
Food consumed during 24 hour testing period1.01.43.6-1.31.3-1.31.6-1.7-1.91.3-1.8-0.6-1.3-1.0-1.6-1.1-1.11.1-0.2-1.5-1.0-1.20.2-0.9-0.8-0.70.20.3-0.2
Glucose0.40.62.2-1.00.5-0.30.9-0.8-0.50.3-0.9-0.2-0.2-0.1-0.20.1-0.60.60.0-1.2-0.6-0.9-0.50.60.90.81.5-1.31.3
Heart weight2.53.88.2-2.92.4-2.42.8-2.7-2.42.4-2.8-1.6-1.9-1.6-2.3-2.0-2.42.4-0.7-2.7-1.5-1.30.1-1.2-0.1-0.20.9-0.60.7
Delay discount hyperbolic model param1.31.53.7-1.91.7-1.71.3-1.2-0.11.4-0.7-1.7-0.9-1.1-0.5-1.2-1.81.8-1.4-1.10.50.40.7-0.50.90.90.9-1.11.1
Intermittent access intake day 1-15 change0.10.30.70.5-0.60.6-0.50.60.8-0.50.50.20.60.30.80.00.7-0.70.40.20.10.2-0.40.70.80.80.2-0.40.4
Intermittent access intake escalation0.20.51.20.8-0.90.8-0.90.91.1-0.80.90.40.90.51.00.20.9-0.90.40.60.30.5-0.40.70.70.7-0.1-0.20.2
Intermittent access intake escalation 20.40.41.00.3-0.60.6-0.60.70.9-0.70.60.40.90.61.00.20.8-0.80.60.20.30.2-0.50.81.00.90.3-0.50.5
Intermitt. access day 1 inactive lever presses0.31.23.8-1.30.5-0.51.3-1.4-1.4-0.0-1.70.1-0.4-0.3-1.0-0.5-1.61.60.7-1.8-1.9-1.8-1.00.10.40.01.2-0.70.8
Intermitt. access day 15 inactive lever presses0.20.42.50.2-0.60.6-0.20.1-0.4-0.4-0.51.10.80.8-0.1-0.1-0.40.41.6-0.4-1.3-1.2-0.90.00.2-0.3-0.20.2-0.2
Intermitt. access escalation Index0.40.61.40.1-0.70.5-1.01.01.1-0.61.00.60.90.91.11.00.7-0.70.20.81.20.5-0.50.60.60.80.2-0.40.4
Intermittent access day 1 total infusions0.71.14.00.40.20.20.5-0.8-1.90.6-1.20.8-0.6-0.2-1.3-0.1-0.10.11.0-0.5-2.0-1.60.1-0.9-1.7-1.7-0.91.4-1.3
Intermittent access day 15 total infusions0.50.72.31.5-1.01.2-0.80.6-0.2-0.70.21.20.60.50.20.40.9-0.91.20.5-1.1-0.6-0.20.1-0.7-0.8-1.01.1-1.0
Intermittent access terminal intake (last 3 days)0.40.61.31.1-0.71.0-0.60.4-0.4-0.30.01.10.30.40.00.30.7-0.71.10.4-1.1-0.7-0.1-0.2-0.9-0.9-1.11.1-1.1
Intermittent access total infusions1.01.14.40.8-0.30.70.1-0.4-1.70.3-1.01.3-0.30.2-1.00.10.4-0.41.5-0.4-2.1-1.7-0.2-0.7-1.6-1.6-1.11.6-1.5
Intermittent access day 1 locomotion0.50.73.70.2-0.30.50.3-0.5-1.3-0.0-1.11.20.10.5-0.50.20.5-0.51.6-1.0-1.6-1.9-1.00.3-0.3-0.40.30.2-0.1
Intermittent access day 15 total locomotion0.30.62.4-0.40.5-0.30.8-0.9-1.50.4-1.40.4-0.6-0.2-1.1-0.6-0.30.30.8-1.0-1.4-1.4-0.2-0.5-0.7-0.7-0.10.6-0.5
Intermittent access total locomotion0.91.13.7-1.00.6-0.41.0-1.1-1.90.8-1.70.6-0.6-0.1-1.4-0.8-0.60.61.2-1.3-1.8-1.9-0.3-0.7-0.7-1.0-0.20.7-0.6
Intermittent access standard deviation0.71.58.1-0.40.5-0.11.5-1.6-1.80.4-2.10.3-0.6-0.5-1.0-0.0-0.50.51.0-2.2-2.8-2.4-1.00.50.1-0.11.3-0.70.9
Left kidney weight6.329.453.1-6.57.3-7.06.8-6.8-5.76.8-5.5-6.1-6.8-6.9-6.5-6.5-6.46.4-5.0-4.2-3.1-0.44.7-5.0-3.6-2.8-0.10.8-0.7
Right kidney weight7.735.061.9-7.27.9-7.67.7-7.7-6.27.1-6.4-6.7-7.3-7.3-7.0-7.3-7.27.2-5.1-5.3-3.5-1.04.5-5.0-3.2-2.50.60.2-0.0
Cocaine induced anxiety1.01.53.1-1.51.8-1.71.4-1.4-1.41.7-1.2-1.2-1.7-1.3-1.5-1.5-1.11.1-1.1-0.8-0.2-0.10.9-1.3-1.0-0.5-0.20.5-0.4
Post-drug Anxiety0.40.51.4-0.80.8-1.00.3-0.20.10.80.0-1.0-0.6-0.7-0.4-1.2-0.70.7-0.90.20.70.91.0-0.8-0.2-0.2-0.50.4-0.5
Baseline Anxiety1.11.32.81.5-1.51.5-1.71.71.5-1.21.60.91.51.01.30.81.2-1.20.81.50.70.8-0.10.60.40.0-0.70.4-0.5
Tail length0.10.42.1-0.3-0.40.2-0.50.61.1-0.60.6-0.01.10.70.6-0.8-0.70.70.40.20.70.5-0.50.31.40.70.3-0.50.5
Length with tail0.62.48.0-2.01.8-1.91.5-1.4-0.61.5-0.9-2.1-1.3-1.7-1.6-2.8-2.72.7-1.5-0.7-0.20.81.5-1.6-0.1-0.7-0.40.3-0.3
Length without tail2.06.511.7-3.33.2-3.23.3-3.2-2.73.0-2.8-2.6-3.0-3.0-3.2-3.0-3.43.4-1.9-2.3-1.8-0.61.7-2.3-1.1-1.30.10.4-0.3
Times rat made contact with spout0.30.31.70.3-0.00.1-0.20.2-0.3-0.2-0.10.20.40.1-0.3-0.9-0.10.10.40.30.30.10.5-0.7-0.7-0.8-1.21.3-1.3
Lifetime Intake1.31.65.80.40.30.20.7-1.0-2.40.9-1.61.0-0.9-0.2-1.60.00.1-0.11.2-0.8-2.4-2.00.0-1.0-2.1-2.0-1.11.7-1.5
Liver weight, left0.91.54.7-0.81.5-1.60.5-0.40.21.20.3-1.9-1.2-1.7-0.5-1.4-1.11.1-2.00.61.11.72.2-1.4-1.2-0.5-1.00.7-0.8
Liver weight, right2.23.912.1-2.22.5-2.91.5-1.20.52.10.1-3.5-2.2-2.5-0.5-2.6-2.52.5-3.4-0.11.92.52.4-1.6-0.20.80.1-0.60.5
Locomotor activity0.91.53.5-1.61.9-1.81.6-1.5-1.11.6-1.3-1.5-1.3-1.4-1.4-1.6-1.31.3-1.1-1.1-0.20.01.0-0.9-0.3-0.30.2-0.10.1
Locomotor testing distance0.10.10.50.0-0.20.1-0.40.40.4-0.50.30.10.60.30.4-0.10.4-0.40.30.20.70.30.10.40.40.30.1-0.10.0
Locomotor testing rearing0.61.22.7-1.61.6-1.61.5-1.5-1.11.6-1.2-1.4-1.4-1.5-1.2-0.9-1.01.0-1.2-1.0-0.4-0.11.1-0.8-0.6-0.30.4-0.10.1
Locomotion in novel chamber2.22.87.21.6-1.81.6-2.22.32.7-1.92.40.82.01.52.51.21.5-1.50.31.82.41.5-0.31.41.41.60.1-0.80.6
Locomotion in novel chamber post-restriction0.50.81.81.2-0.91.0-1.21.21.1-0.81.20.70.90.61.30.91.3-1.30.21.01.00.6-0.00.70.20.70.3-0.10.0
Fecal boli incidents, locomotor time 10.40.63.10.2-0.40.50.0-0.1-0.9-0.4-0.81.30.50.9-0.70.4-0.20.21.7-0.6-1.7-1.6-0.8-0.1-0.1-1.0-0.30.7-0.6
Change in fecal boli incidents, locomotor task2.12.05.6-0.50.9-1.1-0.00.00.21.00.7-1.5-1.2-1.3-0.8-1.8-1.41.4-1.71.30.62.02.4-2.0-1.5-1.6-2.21.9-2.0
Time >=10cm from walls, locomotor time 10.90.92.1-0.90.8-0.81.4-1.4-1.41.0-1.5-0.6-1.2-0.7-1.5-1.1-1.31.3-0.2-1.2-0.8-0.90.2-0.9-0.4-0.70.10.2-0.1
Bouts of movement, locomotor time 11.11.32.4-1.11.4-1.40.9-0.9-0.91.3-0.5-1.2-1.2-1.2-1.2-1.4-1.11.1-1.2-0.00.90.51.4-1.5-1.4-1.1-1.01.0-1.0
Total resting periods, locomotor time 10.80.91.6-0.91.2-1.10.9-0.9-1.10.9-0.8-0.8-0.9-1.0-1.2-1.3-0.90.9-0.6-0.40.4-0.10.9-1.2-1.2-1.1-0.70.9-0.8
Rest time, locomotor task time 11.01.22.8-1.71.3-1.31.3-1.4-1.61.0-1.5-0.6-0.9-1.2-1.5-1.2-1.31.3-0.1-1.1-1.3-0.90.5-0.8-0.9-0.80.00.4-0.3
Distance moved, locomotor task time 10.20.20.90.10.1-0.10.00.10.70.10.5-0.8-0.2-0.40.5-0.10.0-0.0-1.00.20.70.90.20.20.50.80.4-0.70.7
Vertical activity count, locomotor time 10.10.21.4-0.6-0.0-0.10.10.10.40.1-0.0-0.10.30.60.20.1-0.60.6-0.0-0.30.60.1-0.50.11.20.70.6-0.70.7
Time >=10cm from walls, locomotor time 20.10.21.1-0.60.0-0.10.3-0.3-0.20.1-0.40.1-0.10.4-0.4-0.2-1.11.10.3-0.40.1-0.4-0.5-0.30.5-0.10.3-0.20.2
Bouts of movement, locomotor time 20.20.31.6-0.20.8-0.80.2-0.3-0.10.60.1-0.5-0.6-0.70.10.30.9-0.9-1.00.11.30.40.50.1-0.60.40.2-0.30.2
Total resting periods, locomotor time 20.10.21.00.10.6-0.60.2-0.3-0.40.5-0.1-0.2-0.5-0.6-0.10.31.0-1.0-0.60.10.70.10.40.0-0.80.10.00.0-0.0
Rest time, locomotor task time 20.30.43.70.1-0.10.1-0.10.0-0.5-0.0-0.20.40.3-0.5-0.5-0.4-0.20.20.50.2-1.9-0.30.4-0.4-0.9-1.2-0.91.1-1.1
Distance moved, locomotor task time 20.30.41.0-0.70.7-0.60.5-0.40.30.4-0.0-1.0-0.6-0.70.1-0.5-0.60.6-1.0-0.40.50.50.30.10.50.80.7-0.90.9
Vertical activity count, locomotor time 20.30.41.6-1.30.7-0.80.7-0.6-0.20.5-0.6-0.5-0.5-0.1-0.4-0.4-1.31.3-0.3-0.7-0.3-0.2-0.2-0.20.70.40.6-0.60.6
Light reinforcement 10.10.20.70.0-0.40.4-0.10.1-0.1-0.4-0.10.60.30.50.10.80.5-0.50.6-0.2-0.3-0.5-0.70.50.40.20.5-0.10.2
Light reinforcement 20.50.72.2-1.01.0-1.20.8-0.8-0.01.0-0.2-1.4-1.2-1.3-0.1-0.40.0-0.0-1.5-0.31.00.70.7-0.0-0.10.80.9-1.00.9
Bone: marrow area0.91.94.1-1.61.6-1.41.9-1.9-2.01.6-2.0-0.7-1.4-1.1-2.0-1.0-1.71.7-0.4-1.6-1.7-1.30.4-1.0-0.5-1.00.40.10.0
Bone: maximum diameter2.44.59.5-2.32.6-2.43.0-3.1-3.12.4-3.0-1.7-2.5-2.3-3.0-2.1-2.12.1-1.1-2.5-2.1-1.50.9-1.4-1.2-1.20.50.00.1
Bone: maximum force1.73.09.7-1.41.7-1.42.3-2.4-3.11.4-2.8-0.4-1.6-1.6-2.6-1.8-1.11.10.2-2.2-2.7-2.10.2-1.0-1.4-1.60.10.5-0.4
Bone: maximum moment1.93.310.4-1.51.8-1.62.4-2.5-3.21.5-2.9-0.5-1.7-1.6-2.8-2.0-1.21.20.3-2.3-2.7-2.10.3-1.1-1.4-1.70.10.6-0.5
Mean time between licks in bursts0.61.53.81.2-1.31.4-1.11.11.1-1.50.91.01.21.21.51.41.9-1.90.90.40.9-0.0-1.01.61.01.30.8-0.90.8
Mean num. licks in bursts0.81.22.6-1.11.4-1.41.3-1.3-1.01.4-1.0-1.4-1.4-1.5-1.2-1.6-1.21.2-1.1-0.8-0.30.21.1-1.0-0.8-0.4-0.10.3-0.3
Cd content in liver1.01.13.60.40.2-0.40.0-0.0-0.20.70.2-0.8-1.0-0.8-0.8-1.3-0.80.8-0.80.80.31.01.5-1.7-1.3-1.4-1.91.7-1.8
Co content in liver0.50.52.21.1-0.90.9-0.40.3-0.3-1.2-0.31.10.81.10.10.20.8-0.81.5-0.20.5-1.0-0.90.40.1-0.1-0.20.3-0.3
Cu content in liver4.95.912.63.3-3.33.3-2.72.71.9-3.61.92.93.22.92.52.23.1-3.12.61.40.7-0.4-2.32.61.71.30.5-0.70.7
Fe content in liver1.51.85.0-1.81.1-1.22.0-1.9-1.50.9-2.1-0.8-1.1-0.6-1.6-1.1-1.71.7-0.2-2.2-0.7-1.4-0.5-0.21.00.31.6-1.21.3
K content in liver0.50.51.50.8-0.80.9-0.90.90.9-0.80.90.71.20.90.90.90.5-0.50.40.60.50.1-0.40.60.60.30.1-0.20.2
Mg content in liver0.30.30.80.7-0.70.8-0.50.50.3-0.40.30.80.60.90.50.90.2-0.20.60.1-0.4-0.5-0.70.60.60.30.4-0.30.3
Mn content in liver0.30.31.20.30.0-0.1-0.50.50.60.40.9-0.3-0.3-0.30.30.50.0-0.0-1.01.10.11.10.9-0.5-0.6-0.3-0.80.6-0.6
Na content in liver0.80.92.00.7-1.21.2-0.70.80.8-1.40.41.01.41.30.91.00.5-0.51.1-0.0-0.7-0.4-1.11.21.40.90.7-0.80.8
Rb content in liver0.30.31.00.9-0.30.40.1-0.2-0.9-0.4-0.60.8-0.10.4-0.60.10.4-0.40.7-0.3-0.5-1.0-0.6-0.1-0.6-0.7-0.30.6-0.6
Se content in liver0.91.02.81.6-1.11.0-1.21.31.7-1.31.6-0.10.80.21.40.21.1-1.1-0.41.30.81.50.20.80.70.8-0.2-0.30.2
Sr content in liver3.53.06.12.2-2.22.1-2.22.22.1-2.52.01.52.31.52.41.52.4-2.41.21.50.80.7-1.01.91.01.40.1-0.50.4
Zn content in liver0.20.30.60.8-0.50.5-0.60.60.4-0.60.60.10.70.10.2-0.70.2-0.20.10.70.80.50.2-0.1-0.2-0.4-0.60.5-0.6
Bone: minimum diameter0.61.12.9-1.51.4-1.21.5-1.5-1.71.3-1.6-0.4-1.0-0.9-1.6-0.7-0.90.9-0.2-1.3-1.3-1.10.2-0.6-0.6-0.70.4-0.00.1
Time in familiar zone, hab. session 10.50.52.10.40.2-0.0-0.10.1-0.60.2-0.10.3-0.3-0.1-0.7-0.7-0.30.30.30.5-0.4-0.10.5-1.0-1.1-1.4-1.31.4-1.4
Time in novel zone, hab. session 10.80.82.8-1.40.5-0.61.0-0.90.00.5-0.7-0.8-0.3-0.30.10.1-0.50.5-0.6-1.30.0-0.3-0.50.61.21.51.6-1.61.7
Total zone transitions, hab. session 13.04.29.93.0-2.42.4-3.13.12.6-2.03.11.42.41.82.11.11.8-1.80.73.12.01.90.10.40.1-0.3-1.91.3-1.5
Total locomotion distance, hab. session 11.62.27.21.8-1.31.3-2.32.32.2-1.12.60.61.51.01.40.50.6-0.6-0.12.71.72.00.6-0.2-0.0-0.5-1.71.2-1.3
Locomotion velocity, hab. session 11.62.26.42.1-1.61.6-2.32.32.0-1.42.41.01.71.21.40.50.9-0.90.32.51.41.60.20.10.0-0.5-1.51.1-1.2
Time in familiar zone, hab. session 20.50.62.20.5-0.30.3-0.90.91.3-0.81.3-0.40.4-0.01.0-0.40.4-0.4-0.61.21.41.50.30.2-0.00.5-0.4-0.0-0.1
Time in novel zone, hab. session 20.50.52.1-0.50.3-0.20.8-0.8-1.20.7-1.20.4-0.20.1-0.90.3-0.40.40.6-1.1-1.4-1.5-0.2-0.20.1-0.40.30.10.0
Total zone transitions, hab. session 21.01.33.61.9-1.61.8-1.31.20.1-1.10.51.71.21.40.10.60.9-0.91.70.9-0.7-0.6-0.50.0-0.4-1.3-1.21.4-1.4
Total locomotion distance, hab. session 20.70.92.81.2-1.31.5-0.90.80.1-1.00.21.71.41.40.31.10.9-0.91.70.3-0.9-1.0-1.00.60.2-0.6-0.30.5-0.4
Locomotion velocity, hab. session 21.11.44.11.6-1.71.9-1.21.10.2-1.30.42.01.71.70.51.41.1-1.12.00.5-0.9-1.1-1.20.80.3-0.6-0.30.6-0.5
Novel to familiar place preference ratio0.80.93.1-0.71.2-1.31.0-0.9-0.31.3-0.6-1.5-0.9-1.0-0.7-1.8-1.31.3-1.1-0.60.60.61.1-1.10.10.2-0.10.1-0.1
Novelty place preference1.31.44.7-0.91.4-1.61.1-1.0-0.21.6-0.5-1.9-1.1-1.3-0.8-2.2-1.61.6-1.4-0.50.81.01.5-1.4-0.20.1-0.40.3-0.3
Time in novel zone, NPP test1.61.76.1-0.91.5-1.71.2-1.1-0.31.6-0.6-2.1-1.4-1.5-0.9-2.5-1.71.7-1.6-0.50.91.11.6-1.5-0.30.0-0.40.3-0.4
Total zone transitions, NPP test2.94.210.83.3-2.72.8-3.02.92.0-2.32.62.02.42.11.71.41.7-1.71.42.90.91.1-0.20.3-0.2-1.0-2.21.8-1.9
Total locomotion distance, NPP test1.11.53.51.9-1.61.7-1.71.60.9-1.21.31.41.61.30.71.00.8-0.81.11.6-0.00.3-0.30.1-0.3-1.1-1.41.4-1.4
Locomotion velocity, NPP test1.42.04.22.0-1.91.9-2.02.01.3-1.51.71.71.91.61.11.61.3-1.31.21.80.20.4-0.50.5-0.1-0.8-1.21.1-1.2
Intraocular pressure0.81.22.6-1.11.6-1.40.9-0.9-0.81.6-0.4-1.2-1.4-1.5-1.2-1.0-1.41.4-1.30.0-0.50.51.0-1.3-1.2-1.1-0.70.6-0.6
Delta distance traveled before/after self-admin1.11.14.3-1.50.8-0.91.0-0.9-0.90.9-1.0-0.7-0.7-0.4-1.6-1.2-2.12.1-0.3-0.6-0.8-0.20.6-1.5-0.2-1.3-0.81.0-1.0
Delta ambulatory time before/after self-admin1.01.23.6-1.10.7-0.70.9-0.9-1.10.9-1.1-0.5-0.8-0.3-1.7-1.3-1.91.9-0.1-0.6-1.0-0.40.6-1.6-0.4-1.6-1.11.3-1.2
Parametrial fat weight0.30.62.7-0.80.5-0.9-0.20.41.20.50.8-1.00.4-0.20.6-0.6-0.80.8-0.90.41.61.40.5-0.10.90.90.2-0.70.6
Pavlov. Cond. lever latency0.10.20.6-0.20.4-0.40.4-0.4-0.40.4-0.4-0.4-0.5-0.5-0.4-0.8-0.40.4-0.4-0.2-0.20.00.4-0.6-0.4-0.3-0.30.5-0.5
Pavlov. Cond. magazine entry latency0.30.41.20.9-0.70.8-0.70.60.1-0.70.31.10.90.70.40.91.0-1.01.00.4-0.3-0.5-0.40.5-0.3-0.3-0.20.3-0.3
Pavlov. Cond. change in total contacts0.90.93.21.1-1.01.2-0.90.8-0.1-0.70.21.81.11.30.41.81.3-1.31.50.3-0.7-1.1-1.00.7-0.1-0.4-0.20.4-0.4
Pavlov. Cond. index score0.10.20.60.2-0.30.4-0.30.2-0.2-0.2-0.00.80.50.40.00.70.4-0.40.80.1-0.5-0.6-0.40.3-0.2-0.4-0.10.2-0.1
Pavlov. Cond. latency score0.10.10.40.1-0.30.3-0.30.2-0.0-0.20.00.60.50.40.20.60.4-0.40.70.0-0.3-0.5-0.40.50.1-0.10.2-0.10.2
Pavlov. Cond. lever contacts0.50.62.10.5-0.90.9-0.80.80.6-0.80.61.11.11.10.81.40.9-0.90.90.30.1-0.4-0.91.00.60.40.4-0.50.5
Pavlov. Cond. magazine entry number0.40.51.3-1.00.7-0.90.9-0.8-0.10.7-0.5-1.1-0.8-0.7-0.4-0.8-1.01.0-1.0-0.70.30.30.3-0.30.60.60.7-0.80.7
Pavlov. Cond. intertrial magazine entries0.60.72.31.1-1.41.4-0.90.90.4-0.90.41.40.91.50.41.10.6-0.61.30.3-0.3-0.5-1.00.41.0-0.0-0.20.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.60.4-0.40.5-0.50.4-0.0-0.30.20.80.60.50.20.70.5-0.50.70.3-0.3-0.3-0.30.3-0.3-0.4-0.30.3-0.2
Pavlov. Cond. response bias0.30.41.20.7-0.60.8-0.70.60.0-0.60.41.10.80.70.41.10.9-0.90.90.5-0.4-0.4-0.50.5-0.3-0.3-0.20.3-0.2
Pavlov. Cond. lever latency0.70.93.7-0.00.8-0.70.1-0.1-0.20.80.3-0.9-0.9-1.1-0.6-1.2-0.30.3-1.00.80.41.11.9-1.3-1.6-1.1-1.41.3-1.3
Pavlov. Cond. magazine entry latency1.61.95.01.4-1.92.0-0.90.80.1-1.6-0.02.21.72.00.71.91.4-1.42.2-0.2-1.0-1.6-2.21.51.10.30.6-0.20.3
Pavlov. Cond. change in total contacts1.01.66.7-0.90.1-0.01.2-1.3-1.70.3-2.00.9-0.10.5-1.20.6-0.90.91.3-2.1-2.5-2.6-1.90.41.0-0.31.3-0.60.7
Pavlov. Cond. index score0.81.14.10.7-1.31.3-0.40.40.0-1.1-0.21.61.41.50.51.40.6-0.61.6-0.6-0.9-1.5-2.01.31.20.40.8-0.60.6
Pavlov. Cond. latency score1.01.44.30.8-1.51.5-0.60.60.1-1.2-0.11.81.51.70.61.60.8-0.81.8-0.4-0.9-1.5-2.11.31.30.30.7-0.50.5
Pavlov. Cond. lever contacts0.81.14.00.1-0.90.8-0.20.20.3-0.9-0.21.01.01.30.71.30.4-0.41.0-0.7-0.2-1.1-2.01.41.71.21.4-1.41.4
Pavlov. Cond. magazine entry number0.60.82.4-0.81.2-1.20.5-0.5-0.11.00.0-1.3-1.1-1.3-0.4-1.2-0.70.7-1.30.20.71.01.5-1.0-0.9-0.2-0.40.2-0.2
Pavlov. Cond. intertrial magazine entries0.81.22.2-1.21.4-1.31.1-1.2-1.41.5-1.1-0.7-1.3-1.1-1.3-1.3-1.11.1-0.5-0.6-0.7-0.31.3-1.4-1.4-1.0-0.60.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.91.24.30.6-1.31.3-0.40.40.1-1.2-0.21.51.41.50.61.50.7-0.71.6-0.6-0.8-1.4-2.11.41.40.61.0-0.70.8
Pavlov. Cond. response bias0.81.04.50.3-1.00.9-0.10.1-0.1-0.9-0.51.31.01.30.41.40.4-0.41.4-0.8-0.9-1.5-2.11.31.30.71.2-0.91.0
Time in closed arm before self-admin3.03.89.20.4-2.01.7-1.01.11.0-2.30.32.12.12.51.72.61.8-1.82.2-0.7-0.3-1.5-3.02.82.82.12.2-2.22.2
Time in closed arm after self-admin0.20.21.2-1.10.2-0.30.5-0.5-0.70.2-0.80.1-0.3-0.1-0.50.1-0.20.20.3-0.8-0.8-0.8-0.40.00.20.00.4-0.10.2
Time in open arm before self-admin0.40.41.80.30.2-0.2-0.40.40.60.20.8-0.70.0-0.70.2-1.0-0.20.2-0.61.0-0.01.31.1-0.5-0.8-0.5-1.00.7-0.8
Time in open arm after self-admin0.60.61.81.1-0.70.6-1.11.11.3-0.91.30.10.80.61.10.10.8-0.8-0.11.11.11.10.10.40.30.4-0.3-0.1-0.0
Bone: periosteal estimation1.22.46.0-1.81.9-1.72.2-2.3-2.41.7-2.3-0.9-1.8-1.5-2.3-1.2-1.41.4-0.5-1.9-1.9-1.40.4-0.9-0.8-1.00.5-0.00.1
Bone: periosteal perimeter2.54.48.5-2.52.9-2.62.9-2.9-2.62.6-2.6-2.0-2.5-2.5-2.7-2.2-2.22.2-1.5-2.2-1.6-0.91.2-1.5-1.1-1.00.6-0.10.2
Bone: post-yield work0.81.13.40.10.10.00.5-0.7-1.80.5-1.30.7-0.4-0.1-1.6-0.8-0.60.61.1-0.5-1.8-1.4-0.0-1.2-1.3-1.7-1.11.5-1.5
Progressive ratio test 1 active lever presses0.81.03.50.8-0.10.50.3-0.5-1.70.5-1.01.0-0.3-0.1-1.1-0.20.2-0.21.2-0.3-1.9-1.5-0.0-0.7-1.6-1.7-0.91.5-1.3
Progressive ratio test 1 breakpoint0.80.93.00.9-0.20.60.1-0.3-1.50.4-0.81.0-0.2-0.0-1.0-0.10.3-0.31.2-0.1-1.7-1.30.1-0.7-1.6-1.7-1.01.5-1.4
Progressive ratio test 1 inactive lever presses1.01.47.40.1-0.30.60.6-0.8-1.80.3-1.61.60.10.5-0.70.60.7-0.72.1-1.5-2.6-2.7-1.40.5-0.4-0.30.8-0.10.2
Progressive ratio test 2 active lever presses1.11.34.80.6-0.10.4-0.1-0.2-1.40.4-0.60.9-0.40.1-1.10.1-0.10.10.90.3-1.5-1.00.4-1.3-2.1-2.2-1.92.2-2.1
Progressive ratio test 2 breakpoint1.11.35.00.8-0.20.4-0.2-0.1-1.40.3-0.51.0-0.30.1-1.00.10.0-0.00.80.4-1.5-0.90.5-1.2-2.1-2.2-1.92.2-2.2
Progressive ratio test 2 inactive lever presses0.50.92.81.2-1.11.3-1.10.9-0.1-0.70.41.70.91.20.40.70.8-0.81.60.7-0.6-0.8-0.5-0.1-0.7-0.7-1.11.1-1.0
Incentive Sensitization - Responses0.30.42.00.5-0.40.3-0.70.60.2-0.30.60.40.30.40.00.4-0.10.10.20.90.10.30.5-0.7-0.9-1.0-1.41.2-1.3
Incentive Sensitization - Breakpoint0.30.41.90.3-0.20.1-0.50.4-0.0-0.10.40.30.10.2-0.20.2-0.30.30.10.8-0.10.30.6-0.8-1.0-1.0-1.41.3-1.3
Sum of active levers in priming session hrs 5-60.10.10.8-0.0-0.00.10.1-0.10.00.1-0.20.00.00.20.10.0-0.90.9-0.0-0.30.1-0.2-0.4-0.10.40.40.4-0.40.4
Progressive ratio0.10.21.0-0.3-0.10.20.2-0.3-0.4-0.2-0.60.50.20.3-0.1-0.1-0.10.11.0-0.7-0.8-1.0-0.60.40.50.20.4-0.40.5
Food seeking constrained by brief footshock0.40.51.3-0.30.8-0.70.7-0.8-1.20.5-0.8-0.3-1.1-0.9-1.0-0.40.2-0.2-0.5-0.3-0.7-0.30.6-0.6-1.1-0.80.20.8-0.8
Seeking ratio, punishment vs. effort0.20.30.9-0.10.6-0.60.5-0.5-0.70.5-0.4-0.4-0.8-0.7-0.70.00.1-0.1-0.8-0.0-0.30.10.6-0.6-1.0-0.60.10.7-0.7
Retroperitoneal fat weight3.113.026.8-4.95.1-5.24.4-4.3-2.94.9-3.0-4.8-4.8-4.9-3.7-4.1-4.14.1-4.4-2.4-0.30.83.2-3.1-1.8-0.80.4-0.40.4
Reaction time number correct0.71.44.71.2-0.50.3-1.61.61.8-0.32.2-0.10.60.41.30.80.5-0.5-1.12.22.12.10.7-0.3-0.30.1-1.20.6-0.7
Reaction time mean minus median0.00.10.5-0.0-0.10.20.2-0.20.1-0.1-0.20.00.20.20.20.4-0.10.10.1-0.5-0.3-0.4-0.30.50.50.60.7-0.60.6
Reaction time mean minus median AUC0.20.40.8-0.90.8-0.70.9-0.8-0.20.9-0.6-0.9-0.5-0.7-0.2-0.3-0.80.8-0.8-0.8-0.3-0.00.4-0.00.20.60.9-0.70.7
Reaction time num false alarms0.10.20.7-0.30.1-0.10.00.10.5-0.40.1-0.20.20.10.4-0.1-0.00.00.0-0.30.60.1-0.50.50.90.80.7-0.70.7
Reaction time num false alarms AUC0.10.10.8-0.1-0.10.1-0.30.40.7-0.40.5-0.20.20.20.50.10.1-0.1-0.10.20.90.5-0.20.30.60.50.2-0.40.3
Reaction time trials correct on left0.71.44.71.2-0.50.3-1.61.61.8-0.32.2-0.10.60.41.30.80.5-0.5-1.12.22.12.10.7-0.3-0.30.1-1.20.6-0.7
Reaction time trials on left0.81.55.01.3-0.60.4-1.61.71.9-0.42.2-0.10.70.51.40.90.5-0.5-1.12.22.12.10.7-0.2-0.30.1-1.20.6-0.7
Reaction time mean0.20.31.3-0.1-0.30.30.3-0.20.1-0.3-0.30.00.10.30.30.3-0.20.20.2-0.7-0.4-0.5-0.60.70.90.91.1-1.11.1
Reaction time mean AUC0.10.10.60.0-0.30.30.2-0.20.1-0.2-0.2-0.10.00.10.20.1-0.30.30.0-0.4-0.3-0.2-0.20.40.60.60.7-0.80.8
Median of all reaction times0.20.31.20.1-0.50.40.2-0.20.2-0.5-0.20.10.10.30.30.3-0.10.10.1-0.5-0.3-0.4-0.50.70.80.81.0-1.11.1
Reaction time omissions0.40.61.41.0-1.01.1-1.00.90.7-1.20.90.70.60.70.80.91.0-1.00.40.90.40.3-0.20.5-0.2-0.0-0.40.2-0.2
Reaction time false alarm rate0.20.30.9-0.60.1-0.10.4-0.4-0.1-0.3-0.5-0.1-0.0-0.00.0-0.30.0-0.00.4-0.80.0-0.5-0.60.60.90.71.0-0.90.9
Reaction time premature initiation rate0.71.04.4-0.90.1-0.01.0-1.0-1.4-0.1-1.60.7-0.10.2-1.00.4-0.50.51.1-1.6-1.9-2.1-1.00.50.6-0.21.2-0.50.6
Reaction time premature initiations0.10.20.8-0.50.1-0.10.4-0.4-0.6-0.1-0.60.40.00.1-0.50.5-0.50.50.3-0.6-0.8-0.9-0.40.10.2-0.30.4-0.10.1
Std. dev. reaction times0.10.30.8-0.80.3-0.30.7-0.6-0.20.3-0.5-0.6-0.4-0.3-0.2-0.4-0.90.9-0.3-0.8-0.3-0.20.00.00.50.50.7-0.70.7
Reaction time trials completed0.81.55.01.3-0.60.4-1.61.71.9-0.42.2-0.10.70.51.40.90.5-0.5-1.12.22.12.10.7-0.2-0.30.1-1.20.6-0.7
Reaction time trials AUC0.61.13.90.9-0.30.1-1.31.31.6-0.11.9-0.30.40.21.10.70.3-0.3-1.21.91.92.00.7-0.4-0.4-0.0-1.10.5-0.7
Run reversals in cocaine runway, females0.20.20.8-0.3-0.2-0.1-0.50.60.9-0.50.8-0.20.50.40.50.7-0.40.4-0.50.60.80.80.0-0.10.50.40.20.1-0.2
Run reversals in cocaine runway, males1.91.95.60.70.6-0.40.2-0.3-0.70.9-0.0-0.9-1.0-1.5-1.3-2.2-0.60.6-0.80.8-0.40.92.1-1.9-2.2-2.3-2.32.3-2.4
Latency to leave start box in cocaine runway0.30.42.1-0.30.8-0.70.7-0.7-0.10.7-0.2-1.1-0.8-1.0-0.20.1-0.30.3-1.4-0.30.30.50.7-0.1-0.30.4-0.1-0.60.6
Latency to leave start box in cocaine runway, F0.10.10.60.7-0.10.30.0-0.10.00.00.1-0.1-0.1-0.10.20.80.5-0.5-0.50.00.00.1-0.00.3-0.10.2-0.5-0.40.4
Latency to leave start box in cocaine runway, M1.01.03.2-1.31.4-1.51.0-1.0-0.10.9-0.3-1.7-1.0-1.3-0.4-0.7-1.31.3-1.8-0.50.50.81.1-0.6-0.10.50.5-0.50.5
Std. dev. time between licks in bursts0.70.92.41.0-1.31.3-0.80.80.4-1.40.31.41.31.60.61.20.9-0.91.50.10.2-0.8-1.31.01.00.20.4-0.40.4
Total sessions with >9 infusions2.73.310.4-1.41.9-1.42.2-2.4-3.22.3-2.6-0.5-2.2-1.7-2.6-1.2-0.90.9-0.1-1.8-2.5-2.00.7-1.5-2.2-1.8-0.31.1-0.9
Short access day 1 total inactive lever presses1.72.311.0-0.2-0.00.31.3-1.5-2.6-0.2-2.61.4-0.10.7-1.8-0.4-0.90.92.3-2.3-2.8-3.3-1.6-0.10.0-1.10.70.10.1
Short access day 10 total inactive lever presses0.40.93.7-1.60.9-1.11.0-1.0-0.80.8-1.1-0.6-0.6-0.6-1.0-1.2-1.91.90.0-1.0-1.0-0.50.1-0.9-0.0-0.30.00.1-0.1
Short access day 1 total infusions0.81.03.8-0.90.8-0.41.2-1.3-1.91.0-1.80.4-0.8-0.2-1.4-0.3-0.60.60.8-1.5-1.7-1.9-0.4-0.5-0.6-0.70.30.2-0.1
Short access day 10 total infusions1.41.86.3-0.71.3-0.91.7-1.9-2.51.6-2.1-0.1-1.6-1.2-1.8-0.4-0.60.60.2-1.6-2.5-1.80.1-0.7-1.4-1.10.20.4-0.3
Short access total infusions2.02.69.7-0.91.3-0.91.8-2.0-3.12.0-2.50.3-1.8-0.9-2.3-0.4-0.70.70.6-1.7-2.5-2.40.1-1.2-1.9-1.7-0.21.0-0.9
Short access day 1 locomotion0.50.72.8-0.60.2-0.00.9-1.0-1.20.3-1.40.4-0.10.1-0.6-0.0-0.10.10.9-1.5-1.5-1.7-0.80.50.30.11.1-0.70.8
Short access day 10 total locomotion0.91.75.3-0.6-0.40.50.5-0.6-0.7-0.6-1.21.21.00.60.20.6-0.10.11.9-1.8-2.1-2.3-2.01.61.41.02.2-1.71.8
Short access total locomotion1.11.45.0-1.10.6-0.31.4-1.5-1.70.5-2.00.4-0.5-0.4-0.90.1-0.20.20.9-2.1-2.1-2.2-1.00.60.20.21.6-0.91.1
One hour access (0.3 mA shock)1.21.35.22.3-1.31.6-1.10.9-0.2-0.80.31.80.80.90.61.11.9-1.91.60.6-1.0-0.9-0.60.4-0.9-0.5-0.90.9-0.9
Compulsive drug intake1.21.45.10.9-1.10.9-1.51.50.7-1.01.30.80.80.80.20.10.1-0.10.51.90.61.00.6-0.9-1.0-1.5-2.32.2-2.2
One hour access (shock baseline)0.40.62.01.0-0.30.60.1-0.2-0.50.1-0.50.80.10.30.31.01.4-1.40.8-0.7-0.9-1.2-0.80.9-0.00.60.7-0.70.7
Social response proportion1.11.25.20.1-0.10.20.9-0.9-0.40.2-1.10.10.00.30.30.80.8-0.80.4-1.7-0.7-1.3-1.41.51.41.62.3-2.02.0
Social responses0.30.41.11.0-0.60.9-0.40.4-0.1-0.30.00.90.60.70.11.00.9-0.90.90.1-0.5-0.6-0.70.4-0.0-0.4-0.10.4-0.3
Social time1.82.45.22.0-1.92.2-1.31.20.6-1.90.62.11.72.01.32.32.1-2.12.10.2-0.6-1.2-1.81.91.00.50.8-0.60.6
Soleus weight0.20.62.30.2-0.60.7-0.70.6-0.1-0.80.21.01.00.6-0.3-0.0-0.20.21.20.6-1.0-0.30.0-0.5-0.7-1.5-1.41.5-1.4
Bone: stiffness1.32.16.3-1.51.4-1.22.1-2.2-2.41.2-2.5-0.3-1.2-1.1-1.9-1.1-0.90.90.3-2.3-2.1-2.0-0.3-0.3-0.3-0.51.1-0.60.7
Tibialis anterior weight1.44.811.52.9-2.92.9-2.32.21.3-3.21.42.73.12.22.31.73.4-3.42.70.90.2-0.7-1.92.60.91.00.3-0.60.6
Time to tail flick, vehicle, before self-admin0.10.10.50.10.1-0.10.2-0.2-0.40.3-0.40.2-0.10.1-0.4-0.7-0.70.70.6-0.3-0.4-0.5-0.1-0.50.0-0.3-0.20.3-0.3
Time to tail flick, vehicle, after self-admin0.30.41.50.3-1.00.8-0.60.70.8-1.10.40.51.11.10.50.1-0.10.10.80.10.6-0.0-0.70.41.20.20.1-0.20.2
Time to tail flick, test, before self-admin0.30.31.30.00.4-0.5-0.0-0.0-0.00.50.3-0.6-0.6-0.8-0.1-0.30.4-0.4-0.80.60.30.81.0-0.5-1.1-0.5-0.70.6-0.6
Time to tail flick, test, after self-admin0.40.40.90.2-0.70.5-0.80.90.9-0.80.80.40.60.80.80.70.6-0.60.30.70.90.5-0.40.40.40.5-0.1-0.10.1
Delta time to tail flick, vehicle, before/after SA0.30.30.7-0.0-0.60.50.2-0.2-0.2-0.7-0.40.40.30.5-0.00.50.6-0.60.6-0.6-0.1-0.8-0.80.70.60.20.7-0.60.6
Delta time to tail flick, test, before/after SA2.02.04.81.0-1.71.5-1.61.71.7-1.81.31.31.82.21.71.41.1-1.11.20.81.80.2-1.51.31.81.40.6-0.80.7
Tibia length0.82.24.9-0.31.3-1.21.4-1.4-1.91.2-1.3-1.0-1.7-1.6-2.2-2.1-1.71.7-0.8-0.4-1.4-0.21.3-1.8-1.9-2.2-1.31.5-1.4
Ambulatory time before self-admin0.50.71.51.1-1.01.1-0.80.70.4-1.00.41.21.00.81.00.91.2-1.21.10.1-0.2-0.7-1.01.20.40.60.6-0.60.6
Ambulatory time after self-admin0.70.83.11.0-1.31.4-0.70.70.1-1.10.01.51.31.60.20.60.2-0.21.8-0.1-0.5-1.0-1.20.50.9-0.3-0.10.2-0.2
Bone: tissue strength0.40.40.8-0.60.7-0.70.5-0.5-0.40.6-0.2-0.8-0.8-0.8-0.8-0.8-0.90.9-0.70.0-0.10.40.6-0.9-0.6-0.7-0.50.5-0.5
Total heroin consumption0.40.41.70.60.10.10.1-0.2-0.90.6-0.40.3-0.6-0.1-0.80.10.1-0.10.00.2-0.5-0.40.4-0.9-1.3-1.3-1.01.2-1.2
Bone: trabecular number0.10.10.7-0.40.2-0.2-0.20.20.5-0.10.5-0.50.0-0.40.2-0.6-0.10.1-0.50.50.70.80.7-0.0-0.10.1-0.2-0.0-0.0
Bone: trabecular spacing1.41.84.7-0.81.1-1.01.4-1.5-2.21.6-1.8-0.2-1.3-0.9-2.0-1.2-1.41.40.1-1.1-1.9-1.30.3-1.5-1.4-1.7-0.71.3-1.2
Bone: trabecular thickness0.60.82.6-0.1-0.20.1-0.40.51.0-0.70.6-0.00.60.41.20.70.9-0.9-0.20.11.20.5-0.21.31.21.61.3-1.51.4
Bone: trabecular tissue density1.92.87.01.3-1.81.6-1.11.21.4-1.90.71.41.82.11.82.11.5-1.51.4-0.20.8-0.5-2.22.22.72.21.7-1.91.9
Water consumed over 24 hours0.20.31.10.2-0.20.20.1-0.1-0.6-0.3-0.60.30.50.3-0.5-0.7-0.30.30.7-0.3-0.3-0.50.1-0.5-0.4-0.8-0.81.0-1.0
Number of responses in last shaping day1.71.87.60.7-0.71.10.3-0.5-1.3-0.2-1.31.90.51.00.01.71.2-1.21.9-1.5-2.3-2.8-2.11.40.40.51.5-1.11.2