Hub : Genes

Syngr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Syngr1 0.27 0.16 7.7e-03 0.07 0.03 0.11 0.05 2.8e-02 1.3e-01 1.1e-02 6.9e-02
2 RMTg gene expression Syngr1 0.33 0.12 3.3e-07 0.24 0.16 0.19 0.19 4.1e-07 3.8e-05 8.2e-06 7.2e-06
3 NAcc mRNA stability Syngr1 0.05 0.03 2.3e-04 0.04 0.03 0.03 0.04 7.7e-06 8.1e-05 8.4e-05 3.4e-05
4 NAcc intron excision ratio chr7_111654839_111656200 0.1 0.05 4.3e-10 0.09 0.09 0.09 0.1 5.8e-11 2.1e-10 1.0e-10 4.4e-11
5 NAcc intron excision ratio chr7_111654839_111658966 0.09 0.04 7.4e-09 0.08 0.08 0.07 0.08 2.0e-09 3.2e-09 4.6e-09 3.0e-09
6 pVTA isoform ratio NM_019166.2 0.12 0.07 3.1e-03 0.06 0.06 0.07 0.06 1.2e-03 1.1e-03 6.2e-04 1.2e-03
7 PL mRNA stability Syngr1 0.11 0.05 6.9e-07 0.06 0.06 0.06 0.06 1.5e-07 4.3e-07 4.7e-07 2.8e-07
8 BLA mRNA stability Syngr1 0.09 0.05 9.6e-04 0.04 0.05 0.03 0.04 2.0e-03 9.4e-04 1.4e-02 3.5e-03
9 BLA gene expression Syngr1 0.09 0.06 5.0e-03 0.04 0.01 0.03 0.02 2.9e-03 9.0e-02 8.2e-03 2.2e-02
10 pVTA isoform ratio XM_006241971.3 0.14 0.08 5.8e-04 0.08 0.09 0.09 0.07 1.8e-04 1.2e-04 1.5e-04 4.8e-04
11 Liver gene expression Syngr1 0.35 0.11 0.0e+00 0.22 0.29 0.29 0.29 2.0e-24 1.1e-32 1.9e-32 1.6e-32
12 Adipose gene expression Syngr1 0.27 0.11 0.0e+00 0.11 0.14 0.13 0.13 9.5e-12 3.8e-15 5.5e-14 4.3e-14
13 Liver mRNA stability Syngr1 0.59 0.1 0.0e+00 0.29 0.48 0.47 0.47 2.6e-32 1.3e-59 1.5e-58 4.1e-59
14 pVTA alternative polyA NM_019166.2 0.11 0.07 7.4e-03 0.04 0.04 0 0.03 1.0e-02 5.2e-03 2.5e-01 2.3e-02
15 LHb gene expression Syngr1 0.27 0.15 2.1e-03 0.1 0.12 0.04 0.06 2.8e-03 1.0e-03 5.0e-02 1.5e-02
16 PL gene expression Syngr1 0.13 0.07 2.3e-10 0.11 0.09 0.09 0.09 7.4e-12 6.6e-10 3.0e-10 1.9e-10
17 RMTg isoform ratio NM_019166.2 0.22 0.12 8.0e-03 -0 0.06 0.05 0.01 4.8e-01 1.1e-02 1.5e-02 1.7e-01
18 RMTg isoform ratio XM_006241971.3 0.26 0.13 3.9e-03 -0 0.08 0.08 0.02 4.0e-01 3.5e-03 3.7e-03 8.8e-02
19 NAcc gene expression Syngr1 0.08 0.04 1.8e-05 0.04 0.05 0.03 0.04 1.5e-05 4.5e-06 5.4e-04 1.4e-05
20 Brain gene expression Syngr1 0.34 0.09 0.0e+00 0.11 0.23 0.23 0.24 2.3e-10 1.3e-21 2.5e-21 1.3e-22
21 OFC gene expression Syngr1 0.32 0.14 7.6e-04 0.04 0.12 0.08 0.1 5.1e-02 7.5e-04 5.6e-03 2.2e-03
22 Liver intron excision ratio chr7_111654839_111656200 0.08 0.04 1.3e-04 0.02 0.01 0.01 0.02 2.0e-03 2.4e-02 2.0e-02 4.7e-03
23 Liver alternative polyA XM_006241971.3 0.15 0.07 1.2e-08 0.03 0.08 0.06 0.06 3.1e-04 5.8e-09 1.5e-07 3.5e-07
24 Liver isoform ratio NM_019166.2 0.12 0.06 2.7e-06 0.01 0.05 0.04 0.04 7.3e-03 1.3e-06 7.1e-05 5.2e-05
25 Liver alternative polyA NM_019166.2 0.13 0.06 1.4e-07 0.03 0.07 0.06 0.05 6.4e-04 4.8e-08 8.9e-07 1.7e-06
26 Liver isoform ratio XM_006241971.3 0.12 0.06 8.4e-07 0.01 0.06 0.04 0.04 7.0e-03 4.8e-07 4.4e-05 3.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.20.30.60.4-0.20.60.50.40.80.5-0.5-0.60.50.20.50.1-0.60.4-0.7-0.30.30.60.20.8-0.70.7-0.7-0.70.7
Area under the delay curve0.91.03.81.8-1.42.01.21.01.00.9-1.0-0.80.90.90.60.7-1.1-0.6-1.40.1-0.1-0.4-0.9-0.61.0-0.80.80.8-0.8
BMI with tail0.51.74.4-1.21.8-1.0-1.5-1.5-1.4-1.41.22.1-1.9-1.4-0.5-1.41.6-0.90.8-2.02.1-0.60.1-0.6-1.10.4-0.2-0.40.3
BMI without tail0.51.13.30.40.20.80.30.50.60.5-0.60.00.0-0.11.4-0.0-0.00.4-0.7-1.51.51.21.21.2-1.81.7-1.6-1.71.6
Body weight1.25.211.2-3.33.2-3.1-3.1-3.1-2.8-3.03.13.1-2.8-2.7-2.8-2.62.4-1.02.1-1.21.2-1.6-0.7-1.3-0.4-0.50.50.4-0.5
Weight adjusted by age0.40.52.90.1-0.6-0.10.30.30.10.3-0.2-0.20.40.7-0.20.70.11.20.41.7-1.70.10.50.11.2-0.50.50.6-0.6
Bone surface0.10.10.50.2-0.20.00.1-0.10.1-0.10.1-0.40.30.1-0.4-0.0-0.4-0.2-0.40.3-0.3-0.5-0.7-0.30.5-0.60.50.5-0.5
Bone volume0.00.00.10.20.10.1-0.1-0.30.2-0.2-0.0-0.10.00.1-0.10.1-0.00.1-0.1-0.00.0-0.3-0.2-0.0-0.0-0.20.20.1-0.2
Breakpoint value in progressive ratio session0.30.30.80.2-0.20.40.40.50.50.4-0.3-0.40.3-0.20.5-0.2-0.6-0.2-0.7-0.80.80.60.20.5-0.90.8-0.8-0.80.8
Number of licking bursts0.80.92.11.4-1.40.61.20.91.41.0-1.1-1.01.31.20.61.1-1.00.6-0.81.3-1.30.2-0.20.21.1-0.50.40.5-0.5
Context. condit. distance diff. score3.13.810.1-2.62.8-2.5-2.8-2.7-2.5-2.62.13.0-2.6-1.3-1.6-1.03.20.33.0-0.10.1-1.01.0-0.9-0.2-0.40.60.5-0.6
Locomotion velocity, session 10.91.03.70.0-0.5-0.70.1-0.1-0.7-0.10.6-0.00.1-0.3-1.3-0.5-0.5-1.0-0.60.7-0.8-1.2-1.9-1.41.8-1.51.41.5-1.4
Locomotion distance, session 12.02.57.32.7-2.51.82.01.70.91.7-1.6-1.71.81.70.81.4-1.8-0.2-1.81.3-1.3-0.3-1.4-0.62.2-1.31.21.3-1.3
Locomotion velocity, session 20.40.52.5-0.40.7-0.5-0.8-0.7-1.6-0.80.60.5-0.8-0.5-0.6-0.60.5-0.90.3-0.70.7-0.9-0.6-0.80.1-0.50.50.5-0.5
Locomotion distance, session 21.62.27.02.4-2.22.12.11.91.01.9-1.4-2.01.70.90.80.5-2.4-1.0-2.7-0.10.10.0-1.7-0.20.9-0.40.20.3-0.3
Locomotion velocity, session 31.01.24.0-0.50.6-0.9-1.0-1.1-0.6-1.10.40.8-0.50.7-0.60.81.51.42.01.8-1.8-0.70.8-0.41.2-1.11.21.1-1.2
Locomotion distance, session 32.12.38.11.8-1.70.81.10.91.20.9-1.5-0.71.32.40.82.4-0.12.00.52.8-2.8-0.00.6-0.02.2-1.31.31.4-1.4
Stereotopy head waving bouts, day 31.01.12.7-1.41.3-1.5-1.2-1.2-0.8-1.21.51.0-1.1-1.6-1.4-1.60.4-1.30.2-1.11.1-0.8-1.2-0.7-0.3-0.20.10.1-0.1
Stereotopy head waving duration, day 32.83.47.1-2.62.7-2.4-2.4-2.3-2.0-2.42.51.9-2.1-2.6-2.2-2.51.4-1.61.0-1.81.7-1.2-1.1-0.9-0.9-0.0-0.0-0.00.1
Locomotion velocity, session 70.91.03.2-0.91.0-1.8-1.3-1.1-1.3-1.20.90.8-1.1-0.3-0.9-0.21.3-0.31.50.3-0.3-1.20.0-0.90.5-1.01.01.0-1.0
Locomotion distance, session 70.30.41.4-0.10.0-0.8-0.2-0.30.1-0.30.60.2-0.3-0.4-0.9-0.5-0.1-0.9-0.10.1-0.2-1.0-1.2-1.00.8-1.00.91.0-0.9
Stereotopy head waving bouts, day 72.12.35.7-2.32.3-2.3-2.4-2.1-2.3-2.31.61.6-1.8-1.1-1.4-0.92.10.22.3-0.20.2-0.90.5-0.5-0.5-0.30.30.3-0.3
Stereotopy head waving duration, day 71.51.95.5-1.92.2-1.7-2.1-1.8-1.8-1.91.01.4-1.6-0.7-0.5-0.42.20.82.3-0.40.4-0.21.50.2-1.20.4-0.3-0.40.3
Locomotion velocity, session 81.82.14.9-1.71.6-1.9-1.8-1.8-2.2-1.81.91.7-1.6-1.6-2.0-1.61.3-1.21.0-0.50.4-1.5-1.2-1.40.6-1.00.90.9-0.9
Locomotion distance, session 80.20.31.5-0.60.8-0.2-0.7-0.7-1.2-0.60.40.9-0.8-0.2-0.1-0.11.10.30.9-0.10.1-0.10.7-0.2-0.30.00.1-0.0-0.1
Degree of sensitization distance3.23.28.7-2.42.2-1.8-1.7-1.4-1.5-1.52.21.4-1.9-2.9-1.6-2.90.7-2.40.0-2.82.8-0.6-1.0-0.6-1.90.8-0.9-0.91.0
Degree of sensitization stereotypy1.31.44.9-1.41.7-1.4-1.8-1.6-2.0-1.70.91.4-1.3-0.3-0.7-0.12.00.72.20.3-0.3-0.61.0-0.3-0.2-0.30.40.4-0.4
Conditioned locomotion0.20.20.6-0.60.5-0.5-0.6-0.5-0.8-0.60.50.7-0.6-0.4-0.4-0.40.6-0.00.5-0.00.0-0.20.2-0.2-0.1-0.10.10.1-0.1
Cocaine response after cond. corrected0.20.20.9-0.60.2-0.2-0.2-0.2-0.5-0.20.60.3-0.4-0.6-0.6-0.70.0-0.9-0.2-0.50.5-0.5-0.5-0.50.0-0.30.20.3-0.2
Cocaine response after cond. not corrected0.10.10.3-0.50.20.1-0.1-0.0-0.30.00.30.0-0.3-0.5-0.2-0.40.0-0.6-0.1-0.60.6-0.1-0.0-0.1-0.20.2-0.2-0.20.2
Cocaine response before conditioning0.30.31.10.5-0.20.40.30.30.60.4-0.7-0.60.40.70.90.8-0.00.90.30.1-0.10.71.00.8-0.40.7-0.6-0.60.6
Saline control response0.50.72.9-0.2-0.1-0.00.40.50.20.6-0.6-0.70.60.70.70.90.01.60.61.0-1.01.21.71.3-0.50.8-0.8-0.80.8
Bone: connectivity density0.00.00.2-0.1-0.0-0.20.10.10.20.10.1-0.20.3-0.2-0.2-0.2-0.40.1-0.4-0.10.00.2-0.30.3-0.10.2-0.3-0.30.3
Bone: cortical apparent density0.81.14.81.0-0.80.40.30.20.90.2-1.0-0.71.01.70.51.7-0.11.80.62.2-2.20.20.70.41.3-0.70.70.7-0.8
Bone: cortical area1.21.83.2-1.21.6-1.4-1.6-1.8-1.6-1.71.61.6-1.7-1.6-1.5-1.71.1-1.60.5-1.51.5-1.4-1.3-1.3-0.1-0.60.60.6-0.6
Bone: cortical porosity1.41.54.1-1.81.6-1.2-1.1-0.8-1.3-0.91.30.9-1.4-1.8-0.7-1.60.8-1.40.4-2.02.0-0.20.1-0.1-1.80.8-0.8-0.90.9
Bone: cortical porosity2.42.65.8-2.32.1-1.7-1.6-1.3-2.1-1.42.01.3-2.0-2.3-1.3-2.21.1-2.00.6-2.42.4-0.8-0.5-0.7-1.60.5-0.5-0.50.6
Bone: cortical thickness0.20.31.10.30.3-0.2-0.3-0.6-0.2-0.40.30.8-0.6-0.4-0.3-0.50.3-1.0-0.2-0.80.9-0.9-0.9-0.90.3-0.60.60.6-0.6
Bone: cortical thickness0.40.52.40.8-0.30.40.2-0.1-0.00.00.10.7-0.2-0.2-0.3-0.5-0.2-1.2-0.7-0.70.7-0.9-1.5-1.20.9-0.80.90.8-0.8
Bone: cortical tissue density0.81.15.01.0-0.70.40.30.20.80.1-1.0-0.71.01.60.41.6-0.11.70.62.2-2.20.10.60.31.3-0.80.80.8-0.8
Condit. Reinf. active minus inactive responses0.10.10.40.2-0.30.10.0-0.10.5-0.1-0.2-0.50.50.3-0.20.3-0.50.3-0.20.6-0.6-0.1-0.40.00.6-0.40.30.4-0.4
Condit. Reinf. active-inactive response ratio0.20.30.6-0.20.3-0.4-0.6-0.70.1-0.70.20.4-0.20.3-0.40.30.60.50.70.8-0.8-0.40.1-0.30.7-0.60.60.6-0.6
Condit. Reinf. active responses1.01.23.00.9-1.01.21.01.01.51.0-1.3-1.71.61.11.01.1-1.41.3-0.80.8-0.81.20.51.4-0.30.7-0.8-0.80.8
Condit. Reinf. inactive responses2.63.05.71.4-1.61.91.92.02.02.0-2.0-2.42.31.51.91.5-1.91.9-1.20.7-0.72.21.22.3-1.01.6-1.7-1.61.6
Incentive salience index mean0.20.30.70.6-0.70.50.50.30.80.4-0.6-0.80.90.50.20.5-0.80.5-0.60.6-0.60.3-0.20.40.3-0.0-0.00.00.0
Condit. Reinf. lever presses0.30.41.30.6-0.70.60.70.60.70.6-0.7-1.10.90.50.60.5-1.00.5-0.80.2-0.20.60.10.8-0.40.5-0.5-0.50.5
Condit. Reinf. active minus inactive responses0.60.73.40.3-0.3-0.1-0.1-0.30.1-0.30.5-0.30.0-0.3-1.0-0.5-0.5-1.4-0.60.1-0.1-1.3-1.8-1.31.3-1.31.21.3-1.2
Condit. Reinf. active-inactive response ratio0.60.72.8-0.40.3-0.3-0.6-0.7-0.3-0.70.90.1-0.4-0.9-1.3-1.1-0.2-1.5-0.4-0.50.5-1.1-1.7-1.10.7-0.90.80.8-0.8
Condit. Reinf. active responses1.01.43.5-0.30.4-1.0-0.8-1.0-0.7-1.01.10.4-0.8-0.6-1.5-0.80.3-1.70.2-0.0-0.0-1.9-1.8-1.81.5-1.71.71.7-1.7
Condit. Reinf. inactive responses1.01.33.1-0.10.6-1.2-0.9-1.1-0.9-1.10.80.8-1.0-0.2-1.1-0.20.9-1.00.90.3-0.3-1.8-1.1-1.71.4-1.71.71.7-1.7
Condit. Reinf. lever presses0.20.31.10.9-0.60.70.80.71.00.7-0.6-0.90.70.40.50.3-0.8-0.2-0.9-0.10.10.2-0.20.20.10.1-0.2-0.20.2
Condit. Reinf. lever reinforcers received0.71.02.6-0.40.4-0.8-0.6-0.8-0.5-0.71.00.1-0.7-0.7-1.3-0.80.1-1.60.1-0.20.2-1.6-1.6-1.51.0-1.41.31.4-1.3
Conditioned reinforcement - actives0.90.93.91.0-0.80.30.40.10.10.2-0.2-0.20.20.6-0.30.5-0.3-0.8-0.40.9-0.9-1.2-1.2-1.32.0-1.71.61.7-1.6
Conditioned reinforcement - inactives0.80.83.81.2-1.21.11.11.01.81.0-0.7-1.11.10.20.3-0.0-1.6-0.6-1.9-0.10.10.2-1.1-0.00.5-0.0-0.10.00.1
Conditioned locomotion0.91.14.0-0.50.6-0.7-0.7-0.8-0.7-0.81.10.9-0.8-1.2-1.4-1.4-0.0-1.9-0.5-0.90.9-1.3-2.0-1.50.7-1.00.90.9-0.9
Patch foraging indifference point 0 sec0.61.02.40.0-0.40.80.90.91.01.0-0.5-1.11.0-0.20.6-0.1-1.30.4-1.1-0.50.51.30.31.4-1.31.4-1.5-1.51.5
Patch foraging indifference point AUC1.31.65.11.5-1.70.61.00.61.00.7-0.5-0.60.90.8-0.40.6-1.0-0.7-0.91.3-1.3-1.1-1.8-1.32.3-1.91.71.8-1.8
Delay disc. indifference point, 0s delay0.80.94.2-0.81.1-0.3-0.7-0.7-0.4-0.60.80.6-0.9-1.3-0.3-1.30.2-1.2-0.2-2.02.0-0.1-0.3-0.0-1.50.8-0.8-0.80.8
Delay disc. indifference point, 16s delay1.71.74.72.1-1.92.21.81.61.51.5-1.5-1.61.61.41.01.1-1.7-0.3-1.80.6-0.6-0.0-0.8-0.21.3-0.70.60.7-0.6
Delay disc. indifference point, 2s delay0.50.62.31.2-0.41.00.30.1-0.20.1-0.40.1-0.20.30.40.1-0.2-1.5-0.8-1.01.1-1.0-1.0-1.20.5-0.80.90.9-0.9
Delay disc. indifference point, 24s delay1.51.56.11.0-1.20.90.60.30.40.3-0.1-0.20.70.6-0.90.3-0.8-0.3-0.61.5-1.6-1.2-1.8-1.32.5-1.91.81.9-1.8
Delay disc. indifference point, 4s delay0.40.52.00.9-0.71.40.60.50.50.5-0.4-0.40.40.10.1-0.1-0.9-1.0-1.3-0.70.7-0.5-1.2-0.50.3-0.40.40.4-0.4
Delay disc. indifference point, 8s delay1.31.44.21.9-1.82.11.71.41.71.4-1.3-1.01.31.20.90.9-1.4-0.1-1.70.5-0.50.2-0.6-0.11.0-0.40.40.4-0.4
Indifference point function ln k1.31.84.8-2.12.2-1.5-1.8-1.6-1.9-1.61.41.6-1.7-1.1-0.6-0.82.00.42.0-0.70.7-0.01.30.2-1.30.7-0.5-0.60.6
Indifference point function log k1.31.84.8-2.12.2-1.5-1.8-1.6-1.9-1.61.41.6-1.7-1.1-0.6-0.82.00.42.0-0.70.7-0.01.30.2-1.30.7-0.5-0.60.6
Patch foraging total patch changes 0 sec0.81.32.70.4-0.61.31.11.21.41.3-0.8-1.21.20.11.00.1-1.50.5-1.3-0.60.61.50.41.6-1.41.6-1.6-1.61.6
Patch foraging total patch changes 12 sec0.10.21.1-0.1-0.0-0.10.1-0.1-0.1-0.00.3-0.3-0.0-0.5-0.5-0.5-0.5-1.1-0.5-0.50.5-0.5-0.9-0.40.1-0.30.20.3-0.2
Patch foraging total patch changes 18 sec0.60.83.70.3-0.80.50.80.81.10.80.1-0.60.6-0.8-0.3-1.0-1.6-1.3-1.9-1.00.9-0.0-1.7-0.1-0.30.2-0.4-0.30.4
Patch foraging total patch changes 24 sec0.40.51.51.0-1.20.51.11.11.11.2-0.7-1.10.90.40.40.3-1.1-0.2-1.10.1-0.00.2-0.60.10.2-0.0-0.1-0.00.1
Patch foraging total patch changes 6 sec0.71.14.21.0-1.30.91.41.21.71.3-0.7-1.11.4-0.10.2-0.3-2.1-0.5-2.1-0.40.30.5-1.40.30.30.3-0.5-0.40.5
Patch foraging time to switch 0 sec0.60.94.2-1.01.2-0.6-0.8-0.5-0.9-0.60.60.1-1.0-1.00.0-0.90.5-1.20.1-2.02.0-0.20.40.1-1.70.8-0.8-0.80.8
Patch foraging water rate 0 sec0.40.61.40.5-0.90.80.90.81.10.9-0.5-0.41.20.20.20.1-1.21.0-1.00.7-0.81.1-0.20.90.20.6-0.8-0.70.7
Patch foraging water rate 12 sec0.61.02.50.4-0.70.70.91.00.81.1-0.9-0.81.10.71.00.8-0.71.6-0.20.6-0.61.61.01.6-0.81.2-1.2-1.21.2
Patch foraging water rate 18 sec0.91.33.20.7-1.40.81.41.31.41.4-0.9-1.51.80.50.40.5-1.71.3-1.21.1-1.21.4-0.11.40.30.7-0.9-0.80.8
Patch foraging water rate 24 sec0.30.41.5-1.20.7-0.7-0.4-0.4-0.2-0.30.60.2-0.0-0.7-0.5-0.50.10.90.40.2-0.20.80.50.9-0.80.9-0.9-0.90.9
Patch foraging water rate 6 sec1.31.85.50.9-1.40.91.41.41.11.5-1.4-1.61.71.61.11.7-0.92.4-0.02.0-2.11.51.31.60.20.6-0.6-0.60.6
Seeking ratio, delayed vs. immediate footshock0.50.61.30.9-0.61.00.80.80.80.8-1.1-0.80.80.81.10.8-0.60.8-0.50.1-0.10.90.80.9-0.40.7-0.6-0.60.6
Distance traveled before self-admin0.40.41.80.9-0.20.80.40.40.70.4-0.4-0.4-0.10.10.8-0.0-0.4-1.2-0.9-1.31.3-0.2-0.4-0.3-0.50.2-0.1-0.20.2
Distance traveled after self-admin0.50.62.6-0.3-0.00.00.10.20.30.10.5-0.40.3-1.2-0.7-1.3-1.3-1.3-1.5-1.11.0-0.0-1.6-0.1-0.20.3-0.5-0.40.5
Extensor digitorum longus weight0.62.55.41.9-1.32.01.91.92.02.0-1.8-1.11.31.22.31.1-1.20.9-1.8-0.60.71.91.21.5-1.41.7-1.6-1.71.6
Bone: elastic displacement0.00.00.2-0.3-0.0-0.20.00.0-0.40.10.30.2-0.0-0.1-0.4-0.10.10.20.20.5-0.5-0.00.0-0.10.1-0.20.10.1-0.1
Bone: elastic work1.82.35.0-1.91.9-1.2-1.5-1.6-1.9-1.52.01.6-1.8-2.2-1.6-2.21.0-1.80.3-2.02.0-1.0-1.0-0.9-1.00.1-0.1-0.10.1
Bone: endosteal estimation1.02.24.3-2.12.0-1.7-1.9-1.9-2.0-2.02.01.1-1.6-2.0-2.0-1.90.9-1.50.7-1.21.2-1.3-1.2-1.0-0.4-0.40.30.4-0.3
Bone: endosteal perimeter1.63.49.3-2.52.6-2.3-2.4-2.4-3.0-2.42.31.8-2.3-2.1-2.0-2.01.8-1.51.6-1.41.4-1.6-0.6-1.2-0.6-0.50.50.5-0.5
Epididymis fat weight3.06.914.9-3.03.2-3.4-3.5-3.5-3.9-3.53.03.5-3.4-1.9-2.7-1.73.7-0.83.6-0.20.1-2.4-0.1-2.20.8-1.71.81.7-1.8
Delta time in closed arm before/after self-admin1.41.32.9-0.50.8-1.2-1.2-1.2-1.1-1.31.11.2-1.3-0.6-1.2-0.71.2-1.20.8-0.20.2-1.7-1.0-1.71.2-1.51.51.5-1.5
Delta time in open arm before/after self-admin0.60.61.00.4-0.51.00.80.80.70.8-0.7-0.80.80.30.90.3-0.80.4-0.8-0.30.31.00.41.0-0.81.0-1.0-1.01.0
Diff in mean of infusions in LGA sessions0.20.21.30.3-0.3-0.10.10.10.20.00.1-0.10.3-0.0-0.5-0.2-0.5-0.5-0.60.2-0.3-0.5-1.1-0.60.8-0.70.60.7-0.6
Delay discount exponential model param1.11.14.4-1.91.5-2.1-1.3-1.0-1.1-1.01.10.9-1.0-1.1-0.7-0.81.20.51.4-0.30.30.40.90.5-1.10.9-0.8-0.90.8
Extinction: sum of active levers before priming0.20.20.80.9-0.40.40.30.1-0.10.2-0.4-0.30.00.40.30.3-0.2-0.8-0.3-0.40.4-0.7-0.4-0.70.6-0.60.70.6-0.7
Active lever presses in extinction session 60.10.10.5-0.30.4-0.4-0.3-0.3-0.3-0.30.40.3-0.4-0.6-0.3-0.60.1-0.7-0.2-0.70.7-0.3-0.3-0.3-0.20.0-0.0-0.00.0
Bone: final force1.72.85.7-1.31.8-1.2-1.7-2.0-1.3-1.92.01.9-1.9-2.1-2.0-2.21.0-2.40.2-1.91.9-2.0-2.1-1.90.1-1.00.90.9-0.9
Bone: final moment1.82.96.1-1.41.9-1.3-1.7-2.0-1.2-1.92.11.9-1.9-2.2-2.1-2.40.9-2.50.1-2.02.0-2.0-2.2-1.90.1-0.90.90.9-0.8
Food consumed during 24 hour testing period1.41.63.4-1.31.3-1.5-1.3-1.4-1.2-1.31.61.7-1.5-1.8-1.5-1.90.8-1.70.2-1.51.4-1.2-1.4-1.30.1-0.40.40.4-0.4
Glucose0.40.63.0-0.90.5-0.30.20.20.20.30.1-0.70.1-0.60.2-0.5-0.40.0-0.2-0.80.80.80.61.1-1.71.3-1.3-1.31.3
Heart weight0.91.33.3-1.81.4-1.7-1.1-0.9-0.3-0.91.21.2-0.7-1.8-0.9-1.70.4-0.10.1-1.11.10.60.00.5-1.21.2-1.3-1.31.3
Delay discount hyperbolic model param0.91.04.1-1.81.3-2.0-1.1-0.9-0.9-0.91.00.7-0.8-0.9-0.7-0.71.10.71.4-0.0-0.00.50.90.6-0.90.8-0.8-0.80.8
Intermittent access intake day 1-15 change0.90.91.81.1-1.41.01.21.11.11.1-1.1-1.11.21.10.81.1-0.90.9-0.61.2-1.20.70.50.60.70.0-0.1-0.00.0
Intermittent access intake escalation0.80.81.51.1-1.21.01.11.11.11.1-1.1-1.01.11.10.91.0-0.80.8-0.60.9-0.90.70.60.60.50.2-0.2-0.10.2
Intermittent access intake escalation 20.50.50.90.7-1.00.71.00.91.00.9-0.8-0.81.00.60.70.6-0.80.7-0.70.5-0.50.90.50.70.10.5-0.5-0.50.5
Intermitt. access day 1 inactive lever presses0.50.51.6-0.50.30.40.0-0.00.30.00.5-0.1-0.2-1.1-0.4-1.2-0.6-1.0-1.0-1.31.30.1-0.80.1-0.90.7-0.7-0.70.8
Intermitt. access day 15 inactive lever presses0.40.42.00.0-0.3-0.20.0-0.10.1-0.10.5-0.00.0-0.5-0.9-0.7-0.5-0.9-0.80.1-0.1-0.7-1.4-0.91.1-0.80.70.7-0.7
Intermitt. access escalation Index0.30.20.60.7-0.60.50.60.60.80.6-0.6-0.50.50.50.70.4-0.50.3-0.50.0-0.00.40.30.4-0.20.3-0.3-0.30.3
Intermittent access day 1 total infusions1.01.24.1-0.60.9-0.7-0.9-0.9-0.7-1.01.10.7-1.0-1.2-1.2-1.30.3-2.0-0.3-1.21.2-1.4-1.9-1.50.4-0.90.90.9-0.8
Intermittent access day 15 total infusions0.30.31.50.5-0.40.40.30.20.50.10.1-0.40.2-0.2-0.3-0.4-0.7-1.0-1.0-0.20.1-0.5-1.2-0.70.8-0.60.50.6-0.5
Intermittent access terminal intake (last 3 days)0.20.20.80.5-0.30.20.20.10.40.0-0.1-0.40.20.1-0.2-0.1-0.4-0.7-0.70.1-0.1-0.5-0.9-0.60.9-0.70.60.6-0.6
Intermittent access total infusions0.70.84.0-0.00.5-0.3-0.5-0.6-0.2-0.70.70.3-0.7-0.9-0.8-1.1-0.1-2.0-0.8-1.11.1-1.2-1.7-1.30.5-0.80.80.8-0.7
Intermittent access day 1 locomotion0.60.62.4-0.50.6-0.4-0.5-0.5-0.1-0.50.80.4-0.6-1.2-0.7-1.3-0.2-1.5-0.8-1.31.3-0.6-1.5-0.7-0.3-0.00.00.00.0
Intermittent access day 15 total locomotion0.60.61.4-0.50.7-0.9-0.8-0.8-0.3-0.90.90.6-0.7-0.8-1.0-0.90.3-1.1-0.2-0.40.4-1.0-1.2-1.10.7-0.80.70.7-0.7
Intermittent access total locomotion1.11.23.4-1.01.0-1.3-1.0-1.0-0.3-1.11.40.9-0.9-1.6-1.5-1.80.1-1.8-0.5-1.11.1-1.1-1.8-1.20.2-0.50.40.5-0.4
Intermittent access standard deviation0.50.62.4-0.70.7-0.1-0.5-0.6-0.5-0.60.80.3-0.8-1.2-0.6-1.20.0-1.5-0.4-1.41.4-0.5-0.8-0.5-0.50.2-0.2-0.20.2
Left kidney weight8.523.942.8-5.75.8-6.2-6.4-6.5-6.1-6.46.16.2-6.1-4.6-6.0-4.45.6-3.24.8-1.41.3-5.0-2.4-4.71.4-3.33.43.3-3.3
Right kidney weight8.624.143.3-6.35.7-6.4-6.2-6.3-6.0-6.26.66.3-5.9-5.4-6.5-5.34.9-3.54.1-1.81.6-4.7-3.1-4.41.2-2.92.82.8-2.8
Cocaine induced anxiety1.21.33.2-1.41.8-1.3-1.5-1.5-1.3-1.41.21.6-1.5-1.3-0.8-1.21.4-0.61.0-1.41.4-0.60.1-0.4-1.00.3-0.2-0.30.2
Post-drug Anxiety0.70.72.2-1.51.3-1.1-1.1-1.0-0.9-1.01.11.1-0.8-1.3-1.0-1.20.60.00.6-0.60.50.0-0.10.1-0.70.5-0.5-0.50.5
Baseline Anxiety0.91.02.30.8-1.30.81.21.11.21.1-0.9-1.21.50.80.40.8-1.31.1-0.91.5-1.51.00.10.80.60.2-0.3-0.20.3
Tail length0.10.41.1-0.4-0.1-0.20.30.40.80.4-0.1-0.40.6-0.00.20.1-0.41.0-0.20.5-0.61.10.71.1-0.60.9-1.0-0.90.9
Length with tail0.82.88.3-2.92.0-2.8-2.2-2.2-1.9-2.12.31.6-1.3-1.7-2.7-1.61.3-0.01.80.8-0.9-1.1-0.7-0.70.6-0.90.80.8-0.8
Length without tail2.65.713.4-3.12.4-3.4-2.9-3.0-3.0-3.03.02.2-2.1-2.0-3.7-1.91.9-1.02.40.8-0.9-2.5-1.7-2.11.7-2.22.12.2-2.1
Times rat made contact with spout0.30.31.70.6-0.6-0.20.2-0.10.70.00.00.70.20.0-0.4-0.2-0.2-0.0-0.50.5-0.5-0.3-1.2-0.61.3-0.70.70.7-0.7
Lifetime Intake1.41.66.6-0.51.0-0.8-1.0-1.1-0.7-1.11.20.8-1.2-1.4-1.2-1.60.3-2.6-0.6-1.71.7-1.7-2.1-1.70.3-0.90.90.9-0.9
Liver weight, left0.71.23.3-1.41.5-1.3-1.5-1.5-1.5-1.51.11.3-1.3-0.5-1.0-0.41.70.21.80.3-0.4-0.70.5-0.50.3-0.50.60.6-0.6
Liver weight, right2.54.113.5-2.62.8-2.5-3.0-2.8-3.1-2.91.82.3-2.4-0.7-1.4-0.33.30.63.70.7-0.7-1.21.4-0.80.1-0.91.00.9-1.0
Locomotor activity0.91.44.6-1.81.5-2.2-1.4-1.5-1.3-1.41.71.4-1.4-1.5-1.5-1.41.2-0.51.1-0.50.5-0.6-0.3-0.6-0.2-0.10.10.1-0.1
Locomotor testing distance0.10.10.60.2-0.2-0.10.30.20.60.3-0.2-0.20.30.40.20.40.00.70.10.6-0.60.30.40.30.10.1-0.1-0.10.0
Locomotor testing rearing0.81.33.3-1.41.5-1.8-1.5-1.4-1.5-1.41.41.4-1.6-1.2-1.1-1.11.5-0.71.2-0.70.7-0.9-0.2-0.8-0.3-0.30.40.3-0.3
Locomotion in novel chamber4.45.411.02.4-2.62.32.62.62.42.6-2.9-2.42.73.02.83.1-1.43.3-0.72.4-2.32.52.72.50.01.2-1.2-1.21.1
Locomotion in novel chamber post-restriction0.50.61.91.3-0.80.90.90.90.60.9-1.2-0.80.61.31.41.2-0.30.5-0.30.2-0.10.40.70.30.30.1-0.0-0.10.0
Fecal boli incidents, locomotor time 10.50.53.00.4-0.50.00.50.41.10.40.0-0.60.6-0.6-0.4-0.8-1.4-1.1-1.7-0.50.5-0.1-1.6-0.20.2-0.0-0.2-0.10.2
Change in fecal boli incidents, locomotor task1.51.54.2-0.30.1-0.9-0.7-0.8-0.9-0.80.50.7-0.40.6-1.00.61.10.81.52.0-2.1-1.2-0.1-1.12.0-1.81.81.8-1.8
Time >=10cm from walls, locomotor time 10.80.82.0-1.21.0-0.6-0.9-0.9-0.9-0.91.30.7-0.9-1.4-1.2-1.40.3-1.2-0.0-0.90.8-0.7-1.2-0.7-0.2-0.20.10.2-0.1
Bouts of movement, locomotor time 11.21.32.4-0.81.0-1.6-1.3-1.3-1.1-1.31.21.3-1.2-0.7-1.3-0.71.2-0.71.10.1-0.1-1.4-0.8-1.41.0-1.31.31.3-1.3
Total resting periods, locomotor time 10.80.81.6-0.60.7-1.1-0.9-1.0-0.6-1.01.11.0-1.0-0.8-1.2-0.80.8-1.00.5-0.30.3-1.2-1.0-1.30.6-1.01.01.0-1.0
Rest time, locomotor task time 10.70.82.2-0.70.8-1.2-0.8-0.8-0.0-0.81.10.8-0.9-1.3-1.1-1.30.3-1.5-0.2-1.11.0-0.9-1.3-1.0-0.1-0.30.30.3-0.2
Distance moved, locomotor task time 10.30.31.3-0.60.50.1-0.4-0.3-1.0-0.30.10.4-0.30.20.20.30.70.91.10.3-0.30.41.10.5-0.40.4-0.3-0.30.3
Vertical activity count, locomotor time 10.30.31.1-0.70.0-0.10.10.2-0.00.2-0.0-0.10.5-0.3-0.1-0.2-0.40.90.10.3-0.30.90.61.1-0.60.9-0.9-0.90.9
Time >=10cm from walls, locomotor time 20.10.10.3-0.50.1-0.1-0.0-0.00.4-0.00.3-0.20.2-0.6-0.4-0.6-0.6-0.2-0.5-0.20.10.2-0.40.3-0.30.3-0.4-0.40.4
Bouts of movement, locomotor time 20.50.51.4-0.21.0-0.9-1.0-0.9-0.7-0.90.30.7-1.1-0.20.0-0.11.2-0.60.9-0.80.9-0.80.1-0.7-0.2-0.40.50.4-0.4
Total resting periods, locomotor time 20.40.51.00.00.8-0.7-0.8-0.8-0.6-0.80.30.6-1.0-0.2-0.1-0.20.9-1.00.6-0.91.0-1.0-0.3-0.9-0.0-0.50.60.5-0.6
Rest time, locomotor task time 20.30.31.20.5-0.50.10.30.20.30.20.1-0.20.20.0-0.4-0.1-0.4-0.7-0.60.3-0.3-0.6-1.1-0.70.9-0.80.70.8-0.7
Distance moved, locomotor task time 20.30.41.1-1.00.8-0.7-0.7-0.6-0.9-0.60.50.7-0.7-0.4-0.1-0.20.90.51.0-0.20.20.20.90.4-0.80.5-0.4-0.50.4
Vertical activity count, locomotor time 20.30.41.4-1.20.7-1.2-0.7-0.6-0.3-0.60.80.6-0.4-0.9-0.7-0.80.30.10.5-0.30.30.20.10.3-0.60.5-0.5-0.50.5
Light reinforcement 10.00.10.40.00.20.30.0-0.00.30.1-0.1-0.60.3-0.00.0-0.1-0.4-0.0-0.4-0.20.20.2-0.20.3-0.40.3-0.3-0.30.3
Light reinforcement 20.60.82.7-1.01.5-0.4-1.3-1.2-1.2-1.20.60.9-1.3-0.2-0.1-0.01.70.11.6-0.50.5-0.41.1-0.1-1.00.10.1-0.1-0.0
Bone: marrow area1.12.34.5-2.12.0-1.7-1.9-2.0-2.1-2.02.11.1-1.6-2.0-2.0-2.00.9-1.60.7-1.31.2-1.3-1.2-1.0-0.4-0.40.30.4-0.3
Bone: maximum diameter3.15.79.9-2.83.0-2.8-3.0-3.2-3.0-3.13.12.8-2.9-3.0-2.8-3.02.0-2.31.3-2.22.1-2.1-1.7-1.9-0.4-0.80.80.7-0.7
Bone: maximum force2.64.48.9-1.72.3-1.9-2.1-2.4-1.9-2.32.62.4-2.3-2.7-2.5-2.91.1-3.00.1-2.42.4-2.4-2.7-2.30.2-1.11.11.1-1.0
Bone: maximum moment2.74.79.4-1.82.3-2.0-2.2-2.5-1.8-2.32.72.5-2.4-2.8-2.7-3.01.1-3.10.1-2.42.4-2.4-2.9-2.30.1-1.11.11.1-1.0
Mean time between licks in bursts0.81.12.61.2-0.91.31.21.21.11.3-1.4-1.21.10.91.60.9-1.00.6-1.2-0.10.21.30.91.1-0.71.1-1.0-1.01.0
Mean num. licks in bursts0.81.03.0-1.11.1-1.0-1.3-1.3-1.2-1.21.31.7-1.3-1.0-1.1-1.01.2-0.50.9-0.50.4-0.8-0.6-0.90.2-0.50.50.5-0.5
Cd content in liver0.20.20.90.10.20.6-0.1-0.10.0-0.1-0.30.8-0.10.30.60.40.50.90.40.2-0.20.60.80.4-0.40.5-0.3-0.40.4
Co content in liver0.20.20.60.3-0.00.70.30.20.00.2-0.10.50.1-0.30.4-0.4-0.30.1-0.7-0.70.70.6-0.10.4-0.60.8-0.7-0.80.7
Cu content in liver3.03.69.32.6-2.13.02.32.32.02.2-2.5-2.52.32.02.51.9-2.01.5-1.80.4-0.31.71.01.8-0.61.2-1.2-1.21.2
Fe content in liver0.60.82.8-1.71.1-0.1-0.7-0.5-0.6-0.50.8-0.0-0.2-1.1-0.6-1.0-0.10.40.4-0.60.50.70.41.1-1.51.2-1.3-1.31.3
K content in liver0.30.30.90.6-0.60.70.80.70.30.8-0.5-1.00.50.20.50.2-0.7-0.3-0.6-0.30.40.20.10.3-0.30.3-0.3-0.30.3
Mg content in liver0.30.31.50.2-0.20.70.50.4-0.00.5-0.4-1.20.5-0.00.4-0.0-0.8-0.4-0.6-0.70.70.3-0.00.5-0.70.6-0.6-0.60.6
Mn content in liver0.40.41.10.5-0.1-0.3-0.2-0.3-0.8-0.3-0.20.4-0.40.80.20.80.90.31.10.7-0.7-0.70.4-0.60.8-0.91.01.0-1.0
Na content in liver1.41.53.10.9-1.21.41.41.41.41.4-1.3-1.81.60.81.20.8-1.51.0-1.10.3-0.31.50.61.6-0.61.2-1.2-1.21.2
Rb content in liver0.00.10.30.4-0.10.5-0.0-0.2-0.1-0.2-0.0-0.10.2-0.1-0.1-0.2-0.4-0.3-0.5-0.30.3-0.1-0.6-0.10.1-0.10.00.1-0.0
Se content in liver1.51.85.71.4-1.12.11.11.00.91.0-1.6-1.11.32.01.62.1-0.22.40.41.6-1.61.21.81.30.10.4-0.3-0.40.3
Sr content in liver2.52.36.22.5-1.92.21.91.92.31.8-2.1-1.01.52.02.11.9-0.91.4-1.11.0-0.91.31.10.90.40.4-0.3-0.40.3
Zn content in liver1.01.12.51.1-1.31.61.51.40.81.4-1.3-1.51.31.21.21.2-1.00.9-0.60.6-0.61.00.71.0-0.10.5-0.5-0.50.5
Bone: minimum diameter0.91.72.9-1.51.6-1.6-1.5-1.6-1.7-1.61.71.0-1.5-1.7-1.5-1.70.8-1.70.5-1.41.4-1.4-1.2-1.1-0.5-0.50.40.4-0.4
Time in familiar zone, hab. session 10.60.52.00.4-0.1-0.5-0.3-0.50.0-0.50.30.2-0.1-0.1-0.8-0.2-0.1-0.6-0.30.3-0.4-1.0-1.4-1.11.4-1.21.11.2-1.1
Time in novel zone, hab. session 10.80.82.9-1.30.7-0.3-0.30.0-0.8-0.10.40.5-0.4-0.70.2-0.60.40.30.5-0.80.81.01.11.0-1.71.4-1.3-1.41.4
Total zone transitions, hab. session 13.14.49.72.9-2.92.32.32.11.82.1-2.5-2.22.63.11.73.0-1.52.4-0.73.1-3.00.90.70.91.9-0.70.70.8-0.8
Total locomotion distance, hab. session 11.82.69.11.7-2.01.21.41.31.11.2-1.7-1.81.92.40.92.4-0.92.30.23.0-3.00.50.80.71.6-0.80.70.8-0.8
Locomotion velocity, hab. session 11.82.56.91.9-2.11.61.61.41.31.4-1.8-1.92.02.41.02.3-1.22.0-0.32.6-2.60.50.60.71.4-0.70.60.7-0.7
Time in familiar zone, hab. session 20.40.51.70.6-0.40.30.30.20.60.3-0.7-0.00.31.10.71.20.41.30.61.2-1.10.41.20.40.5-0.10.20.2-0.2
Time in novel zone, hab. session 20.40.41.4-0.60.2-0.4-0.1-0.1-0.7-0.10.70.1-0.2-1.1-0.7-1.2-0.5-1.2-0.6-1.01.0-0.2-1.1-0.3-0.40.2-0.3-0.20.3
Total zone transitions, hab. session 20.91.13.11.7-1.61.41.31.10.91.1-0.9-1.21.40.70.20.4-1.7-0.3-1.80.6-0.7-0.1-1.5-0.21.3-0.70.50.6-0.6
Total locomotion distance, hab. session 20.60.82.91.1-1.41.11.31.20.71.2-0.8-1.41.20.40.40.2-1.7-0.4-1.70.1-0.10.4-0.80.30.30.1-0.2-0.20.2
Locomotion velocity, hab. session 20.91.34.31.4-1.71.41.71.51.11.5-1.1-1.81.60.60.60.4-2.1-0.3-2.00.2-0.20.6-0.90.50.30.2-0.3-0.20.3
Novel to familiar place preference ratio0.60.72.4-1.30.9-0.9-1.1-1.0-1.6-1.10.91.5-0.7-0.7-0.9-0.61.00.61.10.3-0.4-0.00.1-0.10.1-0.00.10.0-0.1
Novelty place preference1.01.03.6-1.41.0-1.2-1.3-1.3-1.7-1.31.11.9-1.0-0.7-1.0-0.61.40.71.50.6-0.6-0.20.2-0.30.3-0.30.30.3-0.3
Time in novel zone, NPP test1.21.34.6-1.51.2-1.2-1.5-1.5-1.8-1.51.22.1-1.1-0.7-1.2-0.61.60.81.60.6-0.7-0.30.1-0.40.4-0.40.40.4-0.4
Total zone transitions, NPP test3.04.39.83.0-3.12.42.62.31.72.3-2.4-2.32.62.81.42.5-2.01.5-1.42.7-2.70.6-0.20.42.2-1.00.91.0-0.9
Total locomotion distance, NPP test1.11.54.21.7-2.01.31.61.40.71.5-1.2-1.51.61.40.61.3-1.50.6-1.01.6-1.60.2-0.50.11.5-0.70.60.7-0.6
Locomotion velocity, NPP test1.42.05.12.0-2.31.61.91.71.01.8-1.6-1.91.81.81.01.6-1.60.7-1.11.6-1.60.4-0.10.31.3-0.50.40.5-0.5
Intraocular pressure1.01.43.9-1.11.0-2.0-1.3-1.3-1.3-1.31.31.1-1.3-0.7-1.5-0.61.3-0.91.30.2-0.2-1.6-0.8-1.40.7-1.41.31.3-1.3
Delta distance traveled before/after self-admin0.70.83.7-1.40.5-1.2-0.7-0.7-0.8-0.81.30.7-0.1-1.2-1.9-1.2-0.2-0.10.20.7-0.8-0.4-1.4-0.40.9-0.60.40.5-0.4
Delta ambulatory time before/after self-admin0.80.94.3-1.40.4-1.1-0.6-0.6-0.8-0.71.40.6-0.0-1.4-2.1-1.5-0.5-0.4-0.20.5-0.7-0.5-1.8-0.51.0-0.60.40.5-0.4
Parametrial fat weight0.10.11.0-0.40.2-1.0-0.3-0.20.0-0.30.30.6-0.1-0.1-0.3-0.10.40.60.50.5-0.50.00.1-0.00.3-0.10.10.1-0.1
Pavlov. Cond. lever latency0.20.31.1-0.60.4-0.7-0.5-0.5-0.4-0.50.71.1-0.7-0.6-0.7-0.70.6-0.50.3-0.10.1-0.5-0.5-0.70.5-0.40.40.4-0.4
Pavlov. Cond. magazine entry latency0.30.41.61.3-0.81.00.80.70.80.7-0.7-0.80.60.40.70.3-0.9-0.6-1.2-0.40.40.0-0.6-0.10.2-0.00.00.0-0.0
Pavlov. Cond. change in total contacts0.60.62.31.3-0.80.90.90.80.90.8-0.8-1.20.90.30.60.1-1.4-0.8-1.5-0.50.60.1-1.00.00.20.0-0.1-0.10.1
Pavlov. Cond. index score0.10.10.50.5-0.10.20.20.10.20.1-0.1-0.40.2-0.00.1-0.1-0.5-0.7-0.6-0.50.5-0.3-0.6-0.30.0-0.20.10.1-0.1
Pavlov. Cond. latency score0.10.10.30.3-0.10.30.20.20.20.1-0.2-0.50.20.00.2-0.1-0.5-0.4-0.5-0.40.40.0-0.30.0-0.20.1-0.1-0.10.1
Pavlov. Cond. lever contacts0.30.31.20.7-0.50.70.70.70.50.6-0.7-1.10.70.40.70.4-0.8-0.0-0.7-0.20.30.50.20.5-0.50.5-0.5-0.50.5
Pavlov. Cond. magazine entry number0.20.31.3-1.10.7-0.6-0.5-0.4-0.5-0.40.60.5-0.4-0.6-0.4-0.40.50.50.7-0.10.10.30.50.4-0.70.5-0.5-0.50.5
Pavlov. Cond. intertrial magazine entries0.80.93.30.7-1.20.81.21.11.11.1-0.9-1.51.70.50.30.3-1.80.8-1.30.7-0.81.0-0.61.00.30.5-0.7-0.50.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.7-0.30.40.30.20.30.2-0.4-0.60.30.30.30.2-0.5-0.5-0.6-0.20.2-0.2-0.4-0.20.1-0.20.20.2-0.2
Pavlov. Cond. response bias0.20.20.80.9-0.50.60.50.40.40.3-0.5-0.70.30.30.40.2-0.7-0.7-0.8-0.40.5-0.2-0.5-0.20.1-0.20.10.2-0.1
Pavlov. Cond. lever latency1.11.43.0-0.30.5-1.1-1.1-1.3-1.3-1.20.81.5-1.1-0.1-1.0-0.11.4-0.51.20.5-0.5-1.6-0.6-1.61.6-1.71.71.7-1.7
Pavlov. Cond. magazine entry latency1.71.95.41.4-1.41.71.81.82.01.7-1.3-1.91.80.41.10.2-2.3-0.1-2.2-0.50.51.3-0.41.1-0.71.1-1.2-1.21.2
Pavlov. Cond. change in total contacts0.81.12.7-0.80.3-0.20.20.30.40.30.7-0.90.3-1.6-0.8-1.6-1.5-1.3-1.5-1.51.50.4-1.30.4-1.31.0-1.2-1.11.2
Pavlov. Cond. index score1.21.53.80.9-1.11.31.51.61.91.6-1.0-1.81.50.30.90.2-2.00.1-1.8-0.30.31.3-0.11.3-0.91.2-1.3-1.21.3
Pavlov. Cond. latency score1.41.74.61.0-1.31.41.71.82.01.7-1.1-2.01.70.30.90.2-2.20.1-1.9-0.30.31.4-0.21.3-0.91.2-1.3-1.31.3
Pavlov. Cond. lever contacts0.91.32.80.2-0.30.90.91.11.21.1-0.8-1.51.00.11.00.2-1.20.5-1.1-0.50.61.50.81.6-1.61.6-1.7-1.61.7
Pavlov. Cond. magazine entry number0.60.72.3-0.70.8-0.9-1.1-1.1-1.5-1.00.71.2-1.2-0.2-0.5-0.11.5-0.01.30.2-0.2-0.80.3-0.80.5-0.70.80.8-0.8
Pavlov. Cond. intertrial magazine entries1.11.52.7-0.90.9-1.3-1.3-1.4-1.5-1.31.41.6-1.5-1.2-1.3-1.21.2-1.50.5-0.60.6-1.5-1.2-1.61.0-1.11.11.1-1.0
Pavlov. Cond. lever-magazine prob. diff.1.21.53.50.8-1.01.21.51.51.81.5-1.0-1.81.50.31.00.2-1.90.3-1.7-0.40.41.40.11.4-1.01.3-1.4-1.41.4
Pavlov. Cond. response bias0.71.02.00.4-0.40.90.91.11.21.0-0.6-1.30.9-0.20.7-0.2-1.4-0.2-1.4-0.90.91.10.11.1-1.41.3-1.4-1.31.4
Time in closed arm before self-admin3.94.48.51.1-1.22.21.92.22.42.1-1.7-2.32.10.22.00.2-2.70.4-2.6-1.51.62.60.62.6-2.62.8-2.9-2.92.9
Time in closed arm after self-admin0.70.72.0-1.11.1-0.9-1.0-0.8-0.6-0.91.00.8-0.8-1.4-0.9-1.40.2-1.00.0-1.21.2-0.3-0.7-0.3-0.70.3-0.4-0.30.4
Time in open arm before self-admin0.50.52.10.0-0.3-0.5-0.0-0.3-0.1-0.10.10.4-0.20.6-0.30.70.80.70.91.4-1.5-0.50.4-0.51.1-0.91.01.0-1.0
Time in open arm after self-admin0.80.92.50.7-0.80.90.90.90.91.0-1.2-0.80.81.21.31.3-0.21.50.10.8-0.71.11.61.2-0.50.7-0.7-0.70.6
Bone: periosteal estimation1.63.35.8-2.12.3-1.9-2.3-2.4-2.3-2.42.31.7-2.1-2.3-2.2-2.31.3-2.00.8-1.81.8-1.7-1.5-1.4-0.4-0.60.60.5-0.5
Bone: periosteal perimeter3.15.110.2-2.93.0-2.9-2.8-2.9-3.2-2.82.92.5-2.8-2.7-2.5-2.62.1-2.11.6-1.91.9-2.0-1.2-1.7-0.5-0.70.70.6-0.6
Bone: post-yield work0.60.95.70.00.2-0.3-0.3-0.5-0.3-0.50.70.5-0.3-1.0-1.1-1.3-0.6-1.7-1.2-1.01.0-1.1-2.4-1.20.7-0.70.60.7-0.6
Progressive ratio test 1 active lever presses0.70.83.50.10.2-0.1-0.3-0.40.1-0.40.60.4-0.5-0.8-0.8-1.0-0.3-1.9-1.0-1.11.1-1.2-1.9-1.30.4-0.80.80.8-0.8
Progressive ratio test 1 breakpoint0.50.52.30.20.0-0.0-0.1-0.30.2-0.20.40.2-0.3-0.5-0.6-0.7-0.2-1.4-0.9-0.60.6-1.0-1.5-1.10.6-0.80.80.8-0.8
Progressive ratio test 1 inactive lever presses0.70.84.00.30.10.40.30.30.70.3-0.1-0.5-0.1-0.70.4-0.8-0.7-1.5-1.4-2.02.00.0-0.9-0.1-1.30.7-0.7-0.70.7
Progressive ratio test 2 active lever presses0.70.82.40.5-0.3-0.3-0.1-0.20.1-0.20.20.1-0.1-0.0-0.7-0.2-0.2-1.2-0.50.3-0.3-1.4-1.5-1.41.6-1.51.41.5-1.4
Progressive ratio test 2 breakpoint0.70.82.90.3-0.1-0.4-0.2-0.4-0.0-0.40.40.2-0.3-0.3-0.9-0.5-0.1-1.5-0.5-0.10.1-1.4-1.7-1.51.3-1.41.31.4-1.3
Progressive ratio test 2 inactive lever presses0.50.62.11.3-0.90.80.80.71.10.7-0.6-0.90.60.40.30.2-0.9-1.0-1.4-0.20.2-0.5-1.1-0.70.9-0.60.60.6-0.6
Incentive Sensitization - Responses0.30.31.20.6-0.7-0.10.30.40.40.3-0.4-0.40.40.80.10.8-0.00.40.21.1-1.1-0.20.1-0.31.1-0.70.70.7-0.7
Incentive Sensitization - Breakpoint0.30.31.40.4-0.5-0.40.10.10.10.1-0.2-0.10.10.6-0.10.60.20.20.41.0-1.0-0.5-0.0-0.51.2-0.90.80.9-0.9
Sum of active levers in priming session hrs 5-60.30.30.60.3-0.30.60.50.60.40.5-0.4-0.50.30.00.60.0-0.5-0.1-0.6-0.60.60.60.30.5-0.70.7-0.7-0.70.7
Progressive ratio0.30.31.50.1-0.20.50.40.50.60.5-0.2-0.70.5-0.30.2-0.4-0.9-0.3-1.2-0.60.60.5-0.40.5-0.50.7-0.7-0.70.7
Food seeking constrained by brief footshock0.60.81.5-0.50.9-0.7-0.9-1.0-1.1-1.00.91.0-1.0-0.7-0.9-0.70.8-1.00.5-0.60.6-1.2-1.0-1.20.7-0.90.90.9-0.9
Seeking ratio, punishment vs. effort0.40.51.1-0.20.6-0.6-0.7-0.8-0.8-0.80.61.0-0.9-0.3-0.6-0.30.9-0.60.8-0.30.3-1.0-0.5-1.00.6-0.80.90.9-0.9
Retroperitoneal fat weight3.912.930.0-4.64.7-5.5-5.0-4.8-4.7-4.94.34.6-4.4-3.0-4.0-2.74.5-1.34.5-0.70.6-3.1-0.6-2.70.4-1.92.01.9-2.0
Reaction time number correct0.91.44.51.3-1.20.50.70.70.50.6-1.3-1.00.92.01.02.10.21.70.82.0-2.00.21.20.31.2-0.70.70.7-0.8
Reaction time mean minus median0.10.10.4-0.2-0.0-0.1-0.00.10.10.00.00.0-0.1-0.30.3-0.2-0.0-0.0-0.1-0.40.40.50.40.4-0.60.6-0.6-0.60.6
Reaction time mean minus median AUC0.30.40.8-0.90.6-0.9-0.6-0.5-0.7-0.50.60.7-0.8-0.7-0.1-0.50.8-0.20.7-0.60.60.20.60.0-0.80.5-0.4-0.50.5
Reaction time num false alarms0.20.20.7-0.2-0.1-0.10.30.40.30.4-0.2-0.10.2-0.00.40.1-0.20.60.0-0.00.00.80.80.8-0.60.8-0.8-0.80.8
Reaction time num false alarms AUC0.20.20.60.0-0.40.00.40.50.40.5-0.4-0.40.50.30.40.4-0.20.70.10.4-0.40.70.80.7-0.20.5-0.5-0.50.5
Reaction time trials correct on left0.91.44.51.3-1.20.50.70.70.50.6-1.3-1.00.92.01.02.10.21.70.82.0-2.00.21.20.31.2-0.70.70.7-0.8
Reaction time trials on left1.01.54.81.4-1.30.60.80.70.50.7-1.4-1.10.92.11.12.20.11.70.82.1-2.10.21.20.31.2-0.70.80.7-0.8
Reaction time mean0.20.31.3-0.40.10.30.00.20.10.1-0.0-0.20.0-0.30.4-0.2-0.10.0-0.0-0.60.60.80.60.7-1.11.0-1.0-1.01.0
Reaction time mean AUC0.10.10.6-0.20.00.2-0.00.10.00.1-0.0-0.1-0.0-0.20.3-0.1-0.00.10.1-0.30.40.50.50.4-0.80.6-0.6-0.60.6
Median of all reaction times0.20.31.1-0.2-0.00.60.20.30.20.3-0.2-0.40.1-0.20.5-0.1-0.20.0-0.2-0.60.60.70.60.7-1.00.9-0.9-0.90.9
Reaction time omissions0.30.41.51.2-1.01.20.80.80.40.7-0.8-0.60.40.91.00.8-0.3-0.2-0.30.1-0.10.10.3-0.10.3-0.10.20.2-0.2
Reaction time false alarm rate0.20.30.9-0.60.3-0.10.00.10.20.20.20.2-0.0-0.50.1-0.5-0.20.0-0.3-0.60.60.70.40.7-1.01.0-1.0-1.01.0
Reaction time premature initiation rate0.50.72.0-0.90.6-0.1-0.3-0.2-0.3-0.10.8-0.3-0.2-1.4-0.7-1.4-0.7-1.2-0.8-1.41.40.1-0.90.2-1.00.7-0.9-0.80.9
Reaction time premature initiations0.10.10.3-0.40.1-0.1-0.1-0.1-0.3-0.00.3-0.40.0-0.5-0.4-0.5-0.4-0.4-0.2-0.40.3-0.0-0.40.1-0.20.2-0.3-0.20.3
Std. dev. reaction times0.20.20.8-0.90.4-0.5-0.5-0.4-0.3-0.40.60.5-0.5-0.8-0.3-0.70.4-0.20.4-0.40.40.30.30.2-0.70.5-0.5-0.50.5
Reaction time trials completed1.01.54.81.4-1.30.60.80.70.50.7-1.4-1.10.92.11.12.20.11.70.82.1-2.10.21.20.31.2-0.70.80.7-0.8
Reaction time trials AUC0.71.03.41.1-0.90.20.50.40.20.3-1.1-0.80.61.80.81.80.31.50.91.8-1.80.01.10.21.1-0.70.80.7-0.8
Run reversals in cocaine runway, females0.60.62.50.4-0.60.20.50.50.20.5-0.7-0.70.81.00.51.2-0.11.60.71.5-1.50.70.90.80.30.1-0.1-0.10.1
Run reversals in cocaine runway, males1.61.55.4-0.0-0.2-0.4-0.5-0.7-0.9-0.70.81.0-0.60.1-1.3-0.00.7-0.40.71.3-1.3-1.6-1.2-1.72.3-2.02.02.0-2.1
Latency to leave start box in cocaine runway0.90.93.5-1.11.3-0.9-1.2-1.1-1.9-1.10.81.2-1.5-0.4-0.2-0.31.7-0.21.8-0.60.6-0.50.8-0.4-0.6-0.10.20.1-0.2
Latency to leave start box in cocaine runway, F0.10.10.60.10.30.4-0.1-0.1-0.8-0.1-0.20.0-0.40.30.60.40.5-0.00.6-0.40.5-0.00.70.1-0.70.2-0.0-0.10.1
Latency to leave start box in cocaine runway, M1.91.84.9-1.71.7-1.8-1.7-1.6-2.1-1.61.51.8-2.0-1.1-1.0-0.82.2-0.42.2-0.50.6-0.90.5-0.8-0.1-0.30.40.3-0.4
Std. dev. time between licks in bursts0.70.82.80.7-0.60.91.01.01.20.9-0.8-1.61.30.20.60.1-1.70.2-1.6-0.10.11.0-0.11.0-0.50.8-0.9-0.80.9
Total sessions with >9 infusions2.22.45.2-1.31.6-1.6-1.6-1.7-1.4-1.71.81.6-1.7-1.8-1.8-1.90.9-2.30.2-1.41.4-1.9-2.1-1.90.3-1.11.11.1-1.0
Short access day 1 total inactive lever presses0.91.05.9-0.30.20.0-0.1-0.20.2-0.10.80.10.0-1.5-1.1-1.7-1.2-1.9-1.7-1.41.3-0.5-2.4-0.7-0.1-0.1-0.10.00.1
Short access day 10 total inactive lever presses0.20.20.9-0.90.2-0.3-0.3-0.20.2-0.30.70.00.1-0.8-0.9-0.7-0.30.1-0.10.4-0.50.2-0.40.10.30.1-0.2-0.10.2
Short access day 1 total infusions0.70.82.5-0.80.9-1.0-0.9-0.8-0.5-0.91.00.6-0.9-1.2-0.9-1.30.3-1.6-0.2-1.21.2-0.9-1.3-0.9-0.2-0.30.30.3-0.3
Short access day 10 total infusions2.42.77.7-1.31.9-1.2-1.7-1.8-1.5-1.71.91.5-1.9-2.1-1.6-2.20.9-2.8-0.0-2.32.3-1.7-1.9-1.8-0.4-0.60.70.6-0.6
Short access total infusions2.93.29.0-1.52.0-1.7-1.9-1.9-1.6-1.92.01.6-2.0-2.3-1.8-2.40.9-3.0-0.1-2.42.4-1.9-2.3-1.9-0.3-0.70.70.7-0.7
Short access day 1 locomotion0.40.52.2-0.30.4-0.1-0.10.00.2-0.00.3-0.2-0.2-0.80.0-0.9-0.5-1.3-0.9-1.51.50.0-0.70.0-1.10.6-0.6-0.60.6
Short access day 10 total locomotion1.11.33.8-0.0-0.10.50.60.71.40.8-0.2-0.70.3-0.70.7-0.7-1.0-0.9-1.5-1.71.71.0-0.20.9-1.91.6-1.7-1.71.7
Short access total locomotion1.51.65.3-1.21.3-0.9-0.9-0.9-0.3-0.91.40.8-1.1-2.0-1.0-2.10.0-2.2-0.8-2.32.3-0.5-1.5-0.6-1.30.5-0.5-0.50.6
One hour access (0.3 mA shock)0.60.72.71.7-1.01.20.90.70.80.7-0.9-1.00.50.90.70.7-0.7-0.8-1.1-0.00.1-0.5-0.7-0.71.1-0.80.80.8-0.8
Compulsive drug intake2.42.56.31.8-2.21.31.81.71.71.6-1.7-1.72.12.00.81.9-1.61.6-0.92.5-2.50.60.10.61.8-0.70.60.7-0.6
One hour access (shock baseline)0.30.42.0-0.00.7-0.0-0.5-0.6-0.3-0.50.30.4-0.9-0.50.1-0.50.6-1.2-0.0-1.41.4-0.6-0.3-0.7-0.4-0.00.10.1-0.1
Social response proportion1.31.45.5-0.50.50.80.20.4-0.20.40.1-0.2-0.2-0.90.7-0.9-0.4-0.6-0.8-2.12.11.10.71.0-2.31.9-1.8-1.91.9
Social responses0.20.31.00.6-0.80.30.80.70.70.8-0.4-0.70.60.10.20.0-0.9-0.4-1.0-0.10.10.2-0.5-0.00.1-0.0-0.00.00.0
Social time1.72.24.91.6-1.72.02.12.11.72.2-1.5-2.11.60.81.60.6-2.1-0.3-2.2-0.60.61.2-0.11.0-0.91.1-1.1-1.11.1
Soleus weight0.30.92.51.0-1.60.11.20.91.31.1-0.4-0.81.00.4-0.30.2-1.3-0.5-1.30.9-1.0-0.3-1.2-0.51.4-0.90.70.8-0.7
Bone: stiffness1.82.96.6-1.72.1-1.6-1.8-1.9-1.4-1.92.11.7-1.8-2.5-1.9-2.60.7-2.3-0.0-2.42.4-1.4-1.9-1.3-0.7-0.20.10.1-0.1
Tibialis anterior weight1.03.48.42.9-2.22.72.62.52.72.6-2.2-1.61.91.42.31.1-2.10.1-2.8-0.60.71.40.10.9-0.41.0-1.0-1.01.0
Time to tail flick, vehicle, before self-admin0.20.21.1-0.1-0.2-0.4-0.0-0.1-0.2-0.10.3-0.00.2-0.1-0.7-0.2-0.20.0-0.20.7-0.8-0.3-0.6-0.41.0-0.60.60.6-0.6
Time to tail flick, vehicle, after self-admin0.50.61.60.3-0.80.70.80.80.80.8-0.6-0.71.00.60.50.6-0.71.3-0.31.0-1.01.00.71.0-0.00.5-0.6-0.60.6
Time to tail flick, test, before self-admin0.30.20.80.5-0.30.10.0-0.0-0.3-0.0-0.10.2-0.20.50.00.40.3-0.30.10.4-0.3-0.7-0.3-0.80.9-0.90.90.9-0.9
Time to tail flick, test, after self-admin1.31.32.41.2-1.31.21.31.41.51.4-1.5-1.41.51.21.31.2-1.21.2-1.00.7-0.71.30.91.2-0.20.7-0.8-0.70.7
Delta time to tail flick, vehicle, before/after SA0.50.51.40.2-0.21.00.50.60.60.6-0.4-0.40.30.00.80.0-0.50.1-0.5-0.70.70.90.50.9-1.21.1-1.0-1.11.0
Delta time to tail flick, test, before/after SA3.12.84.91.3-1.51.51.71.82.11.8-2.0-2.02.21.61.81.6-1.72.1-1.11.1-1.12.11.52.2-0.61.4-1.4-1.41.4
Tibia length1.02.85.3-1.41.6-1.2-1.9-2.2-1.4-2.12.01.7-1.7-1.4-2.3-1.51.2-1.60.9-0.40.3-2.3-1.9-2.11.1-1.81.71.8-1.7
Ambulatory time before self-admin0.50.51.61.3-0.81.10.90.81.10.9-1.0-0.90.60.71.10.7-0.7-0.3-1.0-0.30.40.20.00.1-0.10.1-0.1-0.10.1
Ambulatory time after self-admin0.60.63.10.4-1.00.71.00.90.90.9-0.3-1.01.2-0.2-0.2-0.4-1.8-0.3-1.70.1-0.20.5-1.20.40.40.2-0.4-0.30.3
Bone: tissue strength0.20.20.5-0.60.6-0.5-0.5-0.7-0.6-0.50.60.4-0.4-0.3-0.7-0.30.4-0.10.50.2-0.2-0.5-0.3-0.40.3-0.40.40.4-0.4
Total heroin consumption0.20.20.80.4-0.00.0-0.1-0.2-0.4-0.20.10.2-0.10.0-0.4-0.1-0.0-0.6-0.1-0.10.1-0.8-0.9-0.80.8-0.80.80.8-0.8
Bone: trabecular number0.10.10.6-0.10.2-0.3-0.3-0.3-0.2-0.3-0.00.2-0.10.40.10.50.60.80.70.6-0.6-0.00.70.10.1-0.10.20.1-0.2
Bone: trabecular spacing1.31.75.2-0.80.9-1.2-1.0-1.2-1.1-1.21.51.2-1.1-1.7-1.8-1.80.2-2.2-0.3-1.11.1-1.6-2.3-1.70.7-1.11.01.0-0.9
Bone: trabecular thickness0.40.52.30.10.10.20.00.10.30.2-0.6-0.50.20.61.00.70.31.10.4-0.10.20.81.51.1-1.11.0-0.9-0.90.9
Bone: trabecular tissue density1.72.45.30.7-0.91.71.31.41.91.4-1.4-1.61.70.51.50.5-1.71.4-1.3-0.30.32.20.92.3-1.62.1-2.1-2.12.1
Water consumed over 24 hours0.20.31.80.2-0.4-0.20.1-0.10.1-0.00.31.00.0-0.4-0.6-0.5-0.2-0.2-0.40.3-0.3-0.4-1.3-0.61.2-0.60.60.6-0.6
Number of responses in last shaping day1.01.06.20.6-0.00.60.40.30.30.4-0.2-0.4-0.1-0.60.5-0.8-0.8-2.1-1.6-2.42.5-0.4-1.1-0.4-1.00.4-0.4-0.50.5