Sun2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Sun2 0.04 0.02 1.1e-03 0.03 0.03 0.03 0.03 7.5e-04 3.8e-04 2.3e-04 6.8e-04
2 PL mRNA stability Sun2 0.08 0.03 9.4e-11 0.06 0.08 0.09 0.09 2.2e-07 3.8e-09 7.6e-10 8.6e-10
3 BLA intron excision ratio chr7_111284515_111286265 0.09 0.05 1.2e-03 0.03 0.02 0.03 0.01 1.3e-02 2.2e-02 1.6e-02 5.6e-02
4 BLA intron excision ratio chr7_111284539_111286265 0.08 0.05 1.5e-03 0.03 0.02 0.03 0.01 1.4e-02 2.7e-02 1.7e-02 5.4e-02
5 NAcc isoform ratio XM_006242046.4 0.02 0.01 9.8e-03 0.03 0.01 0.01 0.02 6.3e-04 1.1e-02 1.8e-02 4.4e-03
6 NAcc mRNA stability Sun2 0.18 0.07 0.0e+00 0.2 0.17 0.2 0.2 2.3e-22 4.4e-19 1.2e-22 1.7e-22
7 BLA mRNA stability Sun2 0.15 0.07 9.5e-06 0.1 0.09 0.08 0.09 5.2e-06 2.1e-05 5.4e-05 1.3e-05
8 Brain mRNA stability Sun2 0.11 0.05 3.2e-09 0.1 0.09 0.08 0.09 6.8e-10 4.4e-09 5.5e-08 1.3e-08
9 NAcc gene expression Sun2 0.16 0.06 0.0e+00 0.2 0.2 0.21 0.22 2.4e-22 1.9e-22 3.4e-24 1.9e-24
10 NAcc intron excision ratio chr7_111284515_111286265 0.04 0.02 1.7e-05 0.05 0.04 0.04 0.04 1.8e-06 6.5e-06 1.3e-05 9.4e-06
11 NAcc intron excision ratio chr7_111284539_111286265 0.04 0.02 9.7e-05 0.04 0.04 0.04 0.04 9.7e-06 2.3e-05 4.1e-05 4.5e-05
12 Liver gene expression Sun2 0.41 0.17 0.0e+00 0.16 0.15 0.15 0.17 1.5e-17 1.0e-16 1.8e-16 2.3e-18
13 Liver mRNA stability Sun2 0.14 0.07 2.0e-11 0.09 0.1 0.09 0.1 4.1e-10 3.2e-11 3.0e-10 1.0e-11
14 Brain gene expression Sun2 0.11 0.05 4.0e-09 0.1 0.09 0.07 0.1 1.2e-09 6.1e-09 1.9e-07 1.9e-09
15 Adipose mRNA stability Sun2 0.18 0.06 0.0e+00 0.2 0.21 0.2 0.2 1.0e-21 3.5e-23 2.8e-22 3.9e-22
16 BLA gene expression Sun2 0.17 0.07 1.1e-08 0.12 0.14 0.13 0.12 1.0e-06 7.9e-08 2.9e-07 3.6e-07
17 Brain intron excision ratio chr7_111284515_111286265 0.05 0.03 1.5e-03 -0 0.02 0 -0 4.6e-01 1.2e-02 2.4e-01 5.3e-01
18 Brain intron excision ratio chr7_111284539_111286265 0.05 0.03 2.7e-03 -0 0.01 0 -0 4.4e-01 1.9e-02 2.8e-01 6.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.00.10.5-0.30.7-0.20.2-0.1-0.2-0.1-0.30.2-0.20.2-0.00.00.1-0.1-0.0-0.20.2
Area under the delay curve5.05.37.5-2.2-2.7-2.12.1-2.6-2.6-2.3-2.72.3-2.42.42.62.2-2.52.42.21.3-1.2
BMI with tail0.10.20.60.60.20.3-0.30.40.50.50.20.1-0.10.1-0.6-0.50.6-0.5-0.70.3-0.3
BMI without tail0.30.62.4-1.0-0.3-0.70.7-0.3-0.5-0.3-0.41.5-1.61.60.1-0.10.0-0.10.00.6-0.6
Body weight1.87.711.23.32.93.3-3.33.03.12.92.9-2.62.6-2.6-2.8-2.62.8-2.3-2.8-1.71.6
Weight adjusted by age0.60.61.50.30.80.7-0.71.20.91.20.9-0.80.7-0.7-0.9-1.11.0-0.70.3-0.10.1
Bone surface0.10.10.40.10.2-0.10.1-0.3-0.3-0.3-0.40.3-0.40.40.20.1-0.10.60.60.2-0.2
Bone volume0.00.10.3-0.10.5-0.20.2-0.1-0.2-0.1-0.30.3-0.30.3-0.0-0.10.20.00.20.3-0.3
Breakpoint value in progressive ratio session0.40.51.4-0.5-0.4-0.90.9-0.5-0.7-0.5-0.81.2-1.11.10.50.5-0.40.4-0.00.1-0.1
Number of licking bursts0.91.12.0-1.0-0.9-1.21.2-0.8-1.1-0.9-1.01.3-1.31.30.80.6-0.90.91.40.9-0.9
Context. condit. distance diff. score6.37.710.52.73.02.4-2.43.23.23.13.2-2.72.7-2.7-3.1-3.03.1-3.2-2.6-0.60.6
Locomotion velocity, session 10.30.41.60.70.20.7-0.7-0.4-0.3-0.5-0.2-0.60.4-0.40.70.5-0.61.30.7-0.60.7
Locomotion distance, session 14.96.310.3-2.2-2.3-2.52.5-2.7-2.8-2.7-2.42.5-2.52.52.82.2-2.73.03.21.6-1.5
Locomotion velocity, session 20.10.10.60.3-0.1-0.00.0-0.4-0.2-0.4-0.3-0.10.1-0.10.50.3-0.30.80.50.5-0.5
Locomotion distance, session 25.27.211.6-2.3-2.4-2.42.4-3.2-3.2-3.2-3.12.4-2.42.43.33.1-3.23.42.60.7-0.6
Locomotion velocity, session 31.92.24.90.91.61.1-1.11.91.71.91.8-1.11.1-1.1-1.8-2.22.1-1.8-0.30.6-0.7
Locomotion distance, session 31.21.34.3-1.2-0.8-1.41.4-0.1-0.4-0.0-0.21.4-1.41.40.0-0.70.2-0.11.82.1-2.1
Stereotopy head waving bouts, day 30.80.92.11.40.91.5-1.50.60.60.60.3-1.11.0-1.0-0.4-0.10.4-0.1-1.1-1.31.3
Stereotopy head waving duration, day 33.34.06.72.62.12.5-2.51.61.81.61.4-2.52.4-2.4-1.5-1.01.5-1.1-2.2-2.12.0
Locomotion velocity, session 70.40.41.51.21.10.5-0.50.60.70.60.6-0.70.7-0.7-0.5-0.80.6-0.7-0.50.0-0.1
Locomotion distance, session 70.20.30.70.60.20.2-0.2-0.4-0.4-0.5-0.5-0.60.6-0.60.60.7-0.70.5-0.1-0.80.8
Stereotopy head waving bouts, day 73.94.46.22.21.92.3-2.32.42.42.42.2-2.32.2-2.2-2.4-2.22.5-2.0-1.5-0.50.5
Stereotopy head waving duration, day 73.03.66.11.51.31.7-1.72.32.22.42.2-1.81.7-1.7-2.5-2.32.5-2.3-1.40.1-0.1
Locomotion velocity, session 81.51.84.02.01.51.7-1.71.11.31.10.9-1.81.7-1.7-0.9-0.91.0-0.5-1.0-1.00.9
Locomotion distance, session 80.40.61.30.51.10.5-0.50.90.80.80.9-0.90.8-0.8-0.8-0.80.8-0.9-0.5-0.00.0
Degree of sensitization distance3.53.59.12.11.72.2-2.20.50.80.40.5-2.52.5-2.5-0.30.50.1-0.5-2.6-3.03.0
Degree of sensitization stereotypy2.42.64.41.31.31.4-1.42.02.02.01.9-1.61.4-1.4-2.1-2.12.1-1.7-0.70.4-0.4
Conditioned locomotion0.50.61.70.80.60.9-0.90.70.80.80.6-1.31.3-1.3-0.7-0.30.5-0.6-0.5-0.50.5
Cocaine response after cond. corrected0.20.20.70.40.60.8-0.8-0.3-0.1-0.2-0.3-0.50.5-0.50.40.5-0.10.70.1-0.40.5
Cocaine response after cond. not corrected0.10.10.30.20.60.5-0.5-0.1-0.0-0.1-0.1-0.20.2-0.20.20.30.00.4-0.0-0.20.2
Cocaine response before conditioning0.40.41.2-0.8-0.5-1.11.10.1-0.00.00.11.0-1.01.0-0.2-0.30.1-0.50.10.9-0.9
Saline control response0.91.12.30.30.90.8-0.81.41.21.41.5-1.01.0-1.0-1.4-1.01.2-1.5-0.7-0.10.1
Bone: connectivity density0.10.21.40.41.20.4-0.40.30.30.30.3-0.40.4-0.4-0.3-0.30.4-0.2-0.4-0.70.7
Bone: cortical apparent density0.40.51.4-0.60.2-0.70.70.60.50.60.80.5-0.50.5-0.7-1.10.5-0.80.71.1-1.2
Bone: cortical area0.10.21.21.10.60.7-0.7-0.00.20.0-0.1-0.30.3-0.30.1-0.0-0.10.3-0.5-0.30.3
Bone: cortical porosity0.70.81.91.30.91.4-1.40.30.40.30.2-1.11.1-1.1-0.30.20.4-0.1-1.3-1.11.1
Bone: cortical porosity1.11.22.91.71.01.7-1.70.30.50.40.2-1.31.4-1.4-0.30.40.40.1-1.5-1.21.3
Bone: cortical thickness0.61.02.0-0.4-0.7-1.01.0-1.1-1.0-1.0-1.11.4-1.31.31.10.8-1.21.00.50.9-0.9
Bone: cortical thickness1.61.93.7-1.0-1.4-1.31.3-1.7-1.5-1.6-1.31.3-1.11.11.71.5-1.91.71.10.9-0.8
Bone: cortical tissue density0.40.51.2-0.50.3-0.60.60.70.50.60.80.4-0.40.4-0.7-1.10.5-0.80.61.0-1.1
Condit. Reinf. active minus inactive responses0.00.00.0-0.2-0.20.1-0.10.1-0.10.1-0.20.00.0-0.0-0.00.2-0.2-0.1-0.1-0.10.1
Condit. Reinf. active-inactive response ratio0.30.30.80.40.40.4-0.40.80.60.80.6-0.50.5-0.5-0.7-0.70.6-0.9-0.40.1-0.1
Condit. Reinf. active responses0.10.21.3-1.2-0.5-0.40.40.1-0.20.1-0.20.4-0.30.3-0.10.2-0.2-0.6-0.2-0.20.2
Condit. Reinf. inactive responses0.30.43.0-1.7-0.5-0.90.9-0.0-0.3-0.1-0.20.7-0.70.70.00.1-0.1-0.6-0.1-0.20.2
Incentive salience index mean0.10.10.3-0.6-0.3-0.20.2-0.1-0.3-0.1-0.30.3-0.30.30.10.3-0.4-0.1-0.0-0.20.2
Condit. Reinf. lever presses0.10.10.7-0.8-0.4-0.30.3-0.2-0.3-0.3-0.30.5-0.50.50.30.4-0.4-0.1-0.1-0.30.2
Condit. Reinf. active minus inactive responses0.70.82.50.2-1.0-0.40.4-1.2-1.1-1.1-1.10.3-0.30.31.31.4-1.41.60.7-0.20.2
Condit. Reinf. active-inactive response ratio0.40.41.00.6-0.60.6-0.6-0.6-0.5-0.5-0.5-0.30.3-0.30.70.9-0.81.0-0.1-0.70.7
Condit. Reinf. active responses0.30.51.80.8-0.7-0.30.3-0.9-0.6-0.8-0.80.1-0.00.01.01.0-0.91.30.40.0-0.0
Condit. Reinf. inactive responses0.30.40.90.5-0.4-1.01.0-0.6-0.5-0.7-0.60.4-0.40.40.60.4-0.40.80.70.8-0.8
Condit. Reinf. lever presses0.60.81.7-0.7-1.3-1.01.0-1.0-1.1-1.0-1.00.6-0.60.61.01.1-1.00.80.5-0.00.0
Condit. Reinf. lever reinforcers received0.30.51.50.8-0.8-0.10.1-0.9-0.6-0.9-0.7-0.20.2-0.20.91.1-0.91.20.3-0.30.3
Conditioned reinforcement - actives1.81.83.1-0.6-1.7-1.01.0-1.6-1.4-1.6-1.61.0-0.80.81.71.4-1.31.81.61.0-1.0
Conditioned reinforcement - inactives1.61.72.9-1.1-1.2-1.11.1-1.7-1.6-1.7-1.61.3-1.21.21.71.7-1.41.60.8-0.00.1
Conditioned locomotion0.50.62.50.4-1.10.1-0.1-0.8-0.5-0.8-0.80.00.1-0.11.01.6-1.31.40.1-0.30.3
Patch foraging indifference point 0 sec0.30.52.20.10.30.1-0.10.20.20.30.2-0.80.9-0.9-0.30.4-0.2-0.4-0.9-1.51.5
Patch foraging indifference point AUC2.02.34.3-0.9-1.9-1.11.1-1.8-1.8-1.8-1.71.0-0.90.91.81.8-2.02.11.90.7-0.7
Delay disc. indifference point, 0s delay0.10.10.90.2-0.30.2-0.2-0.3-0.1-0.1-0.20.1-0.10.10.30.6-0.30.2-0.9-0.60.6
Delay disc. indifference point, 16s delay5.75.78.2-2.3-2.6-2.12.1-2.7-2.8-2.4-2.92.3-2.32.32.72.4-2.62.72.61.3-1.2
Delay disc. indifference point, 2s delay6.77.59.8-2.0-3.0-2.62.6-2.9-2.9-2.7-2.93.1-3.13.13.02.5-2.72.82.22.2-2.1
Delay disc. indifference point, 24s delay0.70.72.8-0.6-0.6-0.40.4-0.9-0.9-0.7-1.00.4-0.50.51.00.6-0.91.41.70.3-0.3
Delay disc. indifference point, 4s delay2.72.84.5-1.5-1.9-1.31.3-2.0-2.0-1.7-2.01.5-1.61.62.12.0-2.12.01.30.5-0.5
Delay disc. indifference point, 8s delay3.53.65.3-2.1-2.3-1.81.8-2.1-2.2-2.0-2.21.9-2.02.02.01.8-2.01.81.80.8-0.7
Indifference point function ln k2.94.06.51.82.01.8-1.82.42.52.42.3-1.61.6-1.6-2.4-2.32.5-2.4-2.0-0.60.5
Indifference point function log k2.94.06.51.82.01.8-1.82.42.52.42.3-1.61.6-1.6-2.4-2.32.5-2.4-2.0-0.60.5
Patch foraging total patch changes 0 sec0.20.31.3-0.4-0.2-0.30.3-0.1-0.1-0.1-0.1-0.40.5-0.50.10.7-0.5-0.2-0.6-1.11.1
Patch foraging total patch changes 12 sec0.40.61.90.2-0.90.2-0.2-0.9-0.6-0.9-0.8-0.30.4-0.40.81.4-1.41.00.1-0.60.6
Patch foraging total patch changes 18 sec0.91.13.1-0.1-0.80.1-0.1-1.3-1.3-1.4-1.40.10.0-0.01.41.8-1.41.50.1-1.31.3
Patch foraging total patch changes 24 sec0.70.91.8-0.6-0.9-0.90.9-1.3-1.1-1.1-1.20.7-0.60.61.21.3-1.30.90.4-0.10.1
Patch foraging total patch changes 6 sec0.81.12.9-0.5-0.9-0.40.4-1.3-1.3-1.4-1.30.3-0.20.21.41.7-1.71.50.7-0.80.9
Patch foraging time to switch 0 sec0.10.10.40.2-0.10.1-0.1-0.6-0.4-0.6-0.60.1-0.20.20.50.6-0.30.4-0.5-0.20.2
Patch foraging water rate 0 sec0.61.02.30.21.50.8-0.80.90.81.00.8-1.11.2-1.2-0.8-0.50.6-0.8-0.6-1.41.4
Patch foraging water rate 12 sec0.30.51.2-0.30.20.2-0.21.00.91.11.0-0.10.1-0.1-1.0-0.90.8-1.1-0.4-0.10.1
Patch foraging water rate 18 sec0.40.51.5-0.00.80.8-0.80.80.70.90.7-0.60.5-0.5-0.7-0.60.6-0.5-0.2-1.21.2
Patch foraging water rate 24 sec2.94.15.61.51.92.1-2.12.22.22.42.3-2.02.0-2.0-2.2-1.82.1-2.0-1.8-1.61.6
Patch foraging water rate 6 sec0.50.71.8-0.41.00.5-0.51.10.81.21.1-0.00.1-0.1-1.1-1.21.2-1.3-0.1-0.0-0.0
Seeking ratio, delayed vs. immediate footshock0.50.61.8-1.3-1.1-0.90.9-0.6-0.8-0.6-0.60.8-0.90.90.50.5-0.70.30.80.6-0.6
Distance traveled before self-admin2.52.65.4-1.1-2.0-1.11.1-2.3-1.8-2.3-1.91.0-1.01.02.22.1-2.01.91.10.7-0.7
Distance traveled after self-admin0.80.83.10.40.40.8-0.8-0.7-0.4-0.8-0.9-0.70.7-0.70.91.3-0.61.1-0.3-1.71.8
Extensor digitorum longus weight0.72.85.4-2.3-1.8-2.12.1-1.3-1.7-1.2-1.42.3-2.32.31.11.2-1.20.91.31.1-1.1
Bone: elastic displacement0.40.50.90.80.80.7-0.70.70.70.70.7-1.00.9-0.9-0.7-0.60.6-0.4-0.2-0.60.6
Bone: elastic work1.41.83.81.91.41.7-1.70.50.90.60.5-2.02.0-2.0-0.5-0.10.6-0.0-1.3-1.71.7
Bone: endosteal estimation1.12.45.12.21.32.3-2.30.91.20.70.9-2.22.1-2.1-0.8-0.51.1-0.3-1.3-1.51.5
Bone: endosteal perimeter1.12.45.72.41.82.2-2.21.21.41.11.1-1.91.9-1.9-1.2-0.91.3-0.7-1.3-1.01.0
Epididymis fat weight2.66.110.43.22.82.1-2.12.83.02.92.9-2.32.4-2.4-2.7-2.72.7-2.4-2.2-0.10.0
Delta time in closed arm before/after self-admin0.20.20.60.7-0.80.0-0.0-0.4-0.4-0.4-0.3-0.10.3-0.30.40.7-0.60.50.10.5-0.5
Delta time in open arm before/after self-admin0.10.10.6-0.70.1-0.30.3-0.3-0.3-0.4-0.30.5-0.50.50.30.1-0.10.20.1-0.20.2
Diff in mean of infusions in LGA sessions0.20.30.5-0.1-0.4-0.50.5-0.5-0.6-0.5-0.60.7-0.70.70.60.5-0.70.70.3-0.10.1
Delay discount exponential model param5.25.47.92.32.82.2-2.22.62.62.32.6-2.42.4-2.4-2.6-2.22.5-2.4-2.3-1.41.3
Extinction: sum of active levers before priming3.23.24.6-1.2-1.7-1.91.9-1.8-2.0-1.8-2.02.1-2.12.11.71.4-1.61.71.61.6-1.5
Active lever presses in extinction session 60.10.10.20.1-0.1-0.10.1-0.3-0.3-0.2-0.40.2-0.20.20.30.4-0.50.4-0.1-0.10.2
Bone: final force0.30.41.61.30.00.8-0.8-0.5-0.2-0.5-0.5-0.60.7-0.70.50.6-0.41.0-0.3-0.70.7
Bone: final moment0.40.62.11.40.11.1-1.1-0.4-0.1-0.4-0.4-0.90.9-0.90.50.5-0.30.9-0.5-1.01.0
Food consumed during 24 hour testing period0.20.31.31.10.30.8-0.80.10.10.1-0.1-0.40.6-0.6-0.00.20.10.4-0.7-0.50.5
Glucose0.30.51.90.60.50.8-0.80.50.60.50.3-0.20.2-0.2-0.6-0.40.5-0.8-1.4-1.21.2
Heart weight3.24.56.72.22.42.6-2.62.02.32.02.2-1.81.8-1.8-2.1-1.81.8-2.0-2.5-2.22.1
Delay discount hyperbolic model param5.55.98.32.32.92.2-2.22.72.72.42.8-2.52.5-2.5-2.7-2.42.6-2.5-2.3-1.41.4
Intermittent access intake day 1-15 change0.20.20.6-0.6-0.2-0.60.6-0.4-0.4-0.4-0.30.7-0.60.60.30.0-0.00.30.80.5-0.5
Intermittent access intake escalation0.40.40.9-0.7-0.3-0.80.8-0.5-0.5-0.5-0.40.9-0.90.90.40.1-0.10.40.80.7-0.7
Intermittent access intake escalation 20.10.10.4-0.40.0-0.50.5-0.2-0.3-0.2-0.10.6-0.50.50.1-0.10.00.10.20.1-0.1
Intermitt. access day 1 inactive lever presses0.60.62.70.30.60.9-0.9-0.3-0.1-0.3-0.3-0.80.8-0.80.40.6-0.10.4-0.7-1.61.7
Intermitt. access day 15 inactive lever presses0.30.30.70.50.50.4-0.4-0.6-0.3-0.5-0.3-0.50.6-0.60.60.5-0.40.80.2-0.70.8
Intermitt. access escalation Index0.60.51.1-0.9-0.9-0.90.9-0.5-0.6-0.5-0.51.0-1.11.10.30.2-0.60.40.60.7-0.6
Intermittent access day 1 total infusions0.60.72.20.5-0.90.1-0.1-1.2-0.8-1.2-1.1-0.40.5-0.51.11.4-0.91.50.3-0.10.2
Intermittent access day 15 total infusions0.70.82.4-0.2-0.9-0.30.3-1.4-1.0-1.3-1.30.10.1-0.11.21.4-0.91.50.80.0-0.0
Intermittent access terminal intake (last 3 days)0.50.61.6-0.2-0.7-0.40.4-1.2-0.9-1.1-1.00.10.0-0.01.01.1-0.71.30.90.3-0.3
Intermittent access total infusions1.21.43.70.1-1.2-0.40.4-1.8-1.3-1.8-1.70.10.1-0.11.61.8-1.31.90.80.1-0.1
Intermittent access day 1 locomotion0.40.41.60.4-0.50.3-0.3-0.8-0.4-0.8-0.7-0.30.4-0.40.71.3-0.80.9-0.3-0.70.7
Intermittent access day 15 total locomotion0.10.10.50.70.30.1-0.1-0.3-0.1-0.3-0.3-0.20.3-0.30.20.4-0.00.4-0.2-0.10.1
Intermittent access total locomotion0.50.62.01.40.30.8-0.8-0.30.1-0.3-0.2-0.81.0-1.00.30.8-0.00.6-0.8-1.01.1
Intermittent access standard deviation0.50.51.40.60.10.6-0.6-0.8-0.4-0.8-0.7-0.60.9-0.90.81.2-0.50.8-0.5-0.70.8
Left kidney weight6.317.739.96.34.55.2-5.23.94.53.93.9-4.84.8-4.8-3.5-3.43.8-2.8-3.9-2.12.0
Right kidney weight8.423.648.87.05.15.9-5.94.35.04.44.4-5.65.7-5.7-4.0-3.43.9-3.0-5.0-3.63.5
Cocaine induced anxiety0.70.81.90.91.40.7-0.70.90.90.90.8-0.50.4-0.4-0.9-1.11.4-1.0-1.2-0.30.2
Post-drug Anxiety3.13.45.81.32.42.0-2.01.91.81.91.7-2.01.8-1.8-1.8-1.61.9-1.7-1.8-1.81.7
Baseline Anxiety0.20.20.8-0.40.10.3-0.30.40.30.40.5-0.40.4-0.4-0.5-0.3-0.1-0.40.0-0.90.9
Tail length0.51.42.20.71.41.3-1.31.31.21.31.4-0.70.7-0.7-1.3-1.51.5-1.4-1.2-1.11.1
Length with tail2.910.513.83.53.63.7-3.73.43.53.33.4-3.63.6-3.6-3.1-2.83.1-2.6-2.8-2.42.3
Length without tail4.08.815.43.83.03.5-3.52.83.12.82.8-3.93.9-3.9-2.5-2.02.3-1.9-2.4-2.01.9
Times rat made contact with spout0.10.10.3-0.20.3-0.30.3-0.1-0.3-0.2-0.30.5-0.30.30.10.1-0.20.10.20.1-0.1
Lifetime Intake1.21.43.90.4-1.1-0.20.2-1.8-1.3-1.8-1.7-0.10.3-0.31.71.9-1.32.00.4-0.10.1
Liver weight, left1.32.23.41.31.41.6-1.61.71.71.51.8-1.71.8-1.8-1.6-1.41.4-1.3-0.70.1-0.1
Liver weight, right3.76.210.12.42.51.9-1.93.12.83.22.9-2.12.1-2.1-3.1-3.23.1-3.0-2.00.2-0.3
Locomotor activity1.62.53.61.91.61.8-1.81.81.71.81.8-1.51.5-1.5-1.7-1.21.5-1.3-1.7-1.00.9
Locomotor testing distance0.10.20.5-0.1-0.0-0.10.10.60.40.60.70.2-0.10.1-0.6-0.40.4-0.6-0.20.5-0.5
Locomotor testing rearing0.50.82.11.20.61.4-1.41.00.90.91.1-0.70.7-0.7-0.9-0.60.6-0.7-1.1-0.10.1
Locomotion in novel chamber1.11.44.7-2.2-0.5-1.81.80.3-0.40.30.21.5-1.61.6-0.2-0.60.2-0.91.21.4-1.4
Locomotion in novel chamber post-restriction2.32.84.7-1.7-1.9-2.22.2-1.3-1.7-1.4-1.22.1-2.02.01.11.2-1.20.91.41.9-1.9
Fecal boli incidents, locomotor time 10.91.02.8-0.0-0.40.2-0.2-1.1-1.3-1.4-1.1-0.20.3-0.31.21.7-1.41.50.4-1.21.2
Change in fecal boli incidents, locomotor task1.00.92.70.90.40.5-0.51.21.31.21.2-0.50.5-0.5-1.2-1.61.2-0.80.30.8-0.9
Time >=10cm from walls, locomotor time 10.70.71.41.00.71.2-1.20.30.40.20.0-1.11.2-1.2-0.40.20.30.2-0.8-1.21.2
Bouts of movement, locomotor time 10.20.21.21.10.40.4-0.40.40.40.50.5-0.30.4-0.4-0.4-0.40.5-0.2-0.30.2-0.2
Total resting periods, locomotor time 10.10.10.70.8-0.00.3-0.30.10.10.10.0-0.30.3-0.3-0.00.20.00.2-0.2-0.20.2
Rest time, locomotor task time 10.30.31.20.90.30.5-0.5-0.3-0.2-0.3-0.5-0.30.2-0.20.30.30.10.4-0.6-1.11.1
Distance moved, locomotor task time 10.80.92.00.10.70.6-0.61.31.41.21.3-0.70.7-0.7-1.3-1.20.8-1.3-0.60.2-0.2
Vertical activity count, locomotor time 11.61.72.50.71.31.1-1.11.51.61.41.6-1.01.1-1.1-1.5-1.31.3-1.6-1.5-1.21.1
Time >=10cm from walls, locomotor time 20.50.51.50.71.00.8-0.80.30.40.60.3-0.80.8-0.8-0.4-0.30.6-0.1-0.4-1.21.2
Bouts of movement, locomotor time 20.91.02.8-0.3-0.9-1.31.3-0.8-0.6-0.7-0.61.5-1.41.40.40.2-0.10.40.41.7-1.7
Total resting periods, locomotor time 21.41.52.8-0.5-1.3-1.51.5-1.2-1.0-1.1-1.11.7-1.61.60.80.6-0.50.90.61.7-1.6
Rest time, locomotor task time 20.40.41.1-0.2-0.4-0.40.4-0.9-0.8-0.7-1.00.5-0.50.51.00.7-0.51.10.7-0.00.0
Distance moved, locomotor task time 21.11.32.20.71.31.0-1.01.41.41.41.4-0.90.9-0.9-1.5-1.11.1-1.5-1.2-0.50.5
Vertical activity count, locomotor time 21.61.82.71.41.71.2-1.21.31.41.31.3-1.11.1-1.1-1.5-1.21.5-1.3-1.6-1.31.2
Light reinforcement 10.00.10.6-0.2-0.80.4-0.4-0.10.10.10.2-0.10.1-0.1-0.00.3-0.40.2-0.0-0.20.2
Light reinforcement 20.40.51.10.4-0.10.6-0.60.80.90.90.9-0.30.4-0.4-1.1-0.90.9-1.1-0.70.7-0.7
Bone: marrow area1.22.65.52.21.42.3-2.30.91.30.81.0-2.22.2-2.2-0.8-0.51.2-0.3-1.3-1.61.6
Bone: maximum diameter1.62.97.82.81.82.5-2.51.21.51.21.1-2.02.0-2.0-1.1-0.81.1-0.4-1.7-1.51.4
Bone: maximum force0.40.72.81.70.61.3-1.3-0.4-0.0-0.4-0.5-0.90.9-0.90.50.5-0.31.1-0.6-1.01.0
Bone: maximum moment0.61.03.41.90.61.5-1.5-0.30.1-0.3-0.4-1.11.1-1.10.50.5-0.31.1-0.7-1.21.3
Mean time between licks in bursts0.81.12.5-1.4-1.6-1.21.2-0.9-1.0-1.0-1.00.8-0.90.90.91.0-1.10.91.30.7-0.7
Mean num. licks in bursts0.81.01.51.01.00.9-0.91.01.01.01.0-1.01.1-1.1-0.9-0.81.1-1.0-1.2-0.60.5
Cd content in liver0.30.40.9-0.20.2-0.10.10.70.60.80.9-0.10.2-0.2-0.8-0.90.8-0.70.10.9-0.9
Co content in liver0.00.00.1-0.3-0.2-0.30.30.10.1-0.10.10.3-0.20.2-0.0-0.1-0.10.10.10.1-0.1
Cu content in liver3.13.89.3-3.1-1.9-2.52.5-1.6-1.8-1.6-1.42.4-2.42.41.51.3-1.71.11.91.4-1.4
Fe content in liver3.94.67.41.62.62.5-2.52.02.01.92.0-2.72.7-2.7-2.0-1.52.2-1.6-1.8-1.91.9
K content in liver0.60.51.1-0.4-0.5-0.50.5-1.1-0.8-1.0-1.00.6-0.60.61.00.9-0.81.00.70.0-0.0
Mg content in liver0.30.30.8-0.2-0.1-0.30.3-0.9-0.7-0.9-0.70.1-0.10.10.90.8-0.70.70.2-0.30.3
Mn content in liver0.60.62.6-0.4-0.6-1.11.1-0.3-0.5-0.3-0.50.9-0.80.80.30.0-0.30.10.81.6-1.6
Na content in liver0.10.10.7-0.8-0.4-0.20.2-0.2-0.4-0.3-0.40.2-0.10.10.20.4-0.40.10.3-0.20.2
Rb content in liver0.10.10.4-0.2-0.10.0-0.0-0.5-0.4-0.4-0.3-0.10.2-0.20.50.5-0.60.40.2-0.30.3
Se content in liver0.91.13.4-1.6-0.3-1.31.30.60.00.50.51.1-1.01.0-0.7-0.90.7-0.71.01.8-1.8
Sr content in liver3.33.16.3-2.5-1.9-2.32.3-1.1-1.6-1.2-1.32.3-2.22.21.00.8-1.10.61.71.7-1.7
Zn content in liver0.80.91.9-1.4-0.8-1.11.1-0.6-0.8-0.6-0.51.3-1.41.40.60.3-0.50.61.10.8-0.8
Bone: minimum diameter0.20.52.11.40.91.0-1.00.10.20.10.0-0.60.6-0.6-0.0-0.00.30.2-0.9-0.80.8
Time in familiar zone, hab. session 10.30.31.10.2-0.7-0.30.3-0.6-0.6-0.6-0.80.1-0.10.10.70.7-0.51.01.00.2-0.2
Time in novel zone, hab. session 11.51.52.40.71.51.0-1.01.31.41.31.5-1.01.1-1.1-1.4-1.21.4-1.3-1.5-0.80.7
Total zone transitions, hab. session 11.82.56.3-2.2-1.3-2.12.1-0.7-1.2-0.8-0.91.9-1.81.80.80.3-0.90.72.52.1-2.1
Total locomotion distance, hab. session 10.40.62.2-1.0-0.1-1.01.00.3-0.00.30.20.8-0.80.8-0.2-0.50.0-0.31.41.5-1.5
Locomotion velocity, hab. session 10.60.82.3-1.3-0.5-1.01.0-0.1-0.5-0.2-0.31.1-1.11.10.2-0.0-0.50.11.51.4-1.3
Time in familiar zone, hab. session 20.40.41.3-0.6-0.3-0.70.70.50.20.50.50.6-0.60.6-0.5-0.80.5-0.60.61.1-1.2
Time in novel zone, hab. session 20.40.41.10.60.30.7-0.7-0.4-0.2-0.4-0.4-0.40.5-0.50.40.7-0.50.6-0.7-1.01.1
Total zone transitions, hab. session 21.51.93.5-1.2-1.0-1.31.3-1.6-1.7-1.7-1.80.8-0.80.81.71.7-1.71.91.60.1-0.1
Total locomotion distance, hab. session 21.01.33.3-0.8-0.8-0.70.7-1.4-1.4-1.4-1.50.4-0.30.31.51.8-1.71.61.1-0.30.3
Locomotion velocity, hab. session 21.31.74.0-1.0-1.0-0.90.9-1.6-1.6-1.6-1.70.6-0.50.51.72.0-1.91.81.3-0.30.4
Novel to familiar place preference ratio2.93.04.81.41.91.5-1.52.12.12.12.2-1.61.6-1.6-2.1-2.12.0-1.7-1.2-0.50.4
Novelty place preference3.83.86.31.52.01.6-1.62.52.42.52.5-1.71.7-1.7-2.5-2.52.4-2.0-1.3-0.30.3
Time in novel zone, NPP test4.44.57.21.72.21.8-1.82.72.62.62.7-1.81.9-1.9-2.7-2.72.6-2.2-1.4-0.30.3
Total zone transitions, NPP test2.33.37.9-2.2-1.4-2.22.2-1.5-1.8-1.6-1.61.8-1.81.81.61.2-1.81.62.81.6-1.6
Total locomotion distance, NPP test0.71.02.7-1.0-0.6-0.90.9-1.1-1.1-1.1-0.90.5-0.50.51.21.2-1.51.31.60.4-0.4
Locomotion velocity, NPP test1.31.83.8-1.5-1.0-1.41.4-1.4-1.5-1.5-1.30.9-0.90.91.51.4-1.81.41.90.8-0.8
Intraocular pressure0.20.32.01.40.40.2-0.20.40.50.60.4-0.70.7-0.7-0.4-0.20.5-0.1-0.4-0.00.0
Delta distance traveled before/after self-admin3.43.77.11.92.72.2-2.22.01.82.01.5-2.02.0-2.0-1.7-1.41.8-1.1-1.5-2.22.2
Delta ambulatory time before/after self-admin3.13.46.31.82.52.3-2.31.71.51.71.3-2.12.1-2.1-1.4-0.91.5-0.6-1.3-2.42.4
Parametrial fat weight0.40.71.60.61.10.2-0.21.01.11.21.2-0.20.1-0.1-1.3-1.31.0-1.2-0.8-0.40.3
Pavlov. Cond. lever latency0.20.20.60.80.60.5-0.50.40.40.50.4-0.60.6-0.6-0.4-0.50.5-0.1-0.3-0.30.3
Pavlov. Cond. magazine entry latency1.92.54.1-1.2-2.0-1.21.2-1.9-1.8-1.9-1.81.5-1.41.41.81.9-1.81.91.50.8-0.8
Pavlov. Cond. change in total contacts2.93.15.1-1.3-2.2-1.31.3-2.1-2.1-2.2-2.31.5-1.51.52.12.2-2.22.11.40.5-0.5
Pavlov. Cond. index score0.60.81.7-0.4-1.1-0.40.4-1.1-1.0-1.2-1.10.7-0.70.71.11.3-1.21.10.60.1-0.1
Pavlov. Cond. latency score0.30.41.0-0.3-0.8-0.30.3-0.7-0.7-0.8-0.80.5-0.40.40.81.0-0.80.80.40.0-0.0
Pavlov. Cond. lever contacts0.50.61.4-0.8-0.9-0.60.6-0.9-0.9-1.0-0.90.7-0.70.70.91.2-1.00.70.50.1-0.1
Pavlov. Cond. magazine entry number1.41.72.50.81.61.0-1.01.61.51.61.5-1.21.2-1.2-1.6-1.41.5-1.5-1.4-0.90.9
Pavlov. Cond. intertrial magazine entries0.10.21.0-0.70.5-0.00.00.1-0.10.0-0.0-0.00.0-0.00.10.0-0.2-0.1-0.2-1.01.0
Pavlov. Cond. lever-magazine prob. diff.0.81.01.7-0.6-1.3-0.70.7-1.2-1.1-1.3-1.21.0-0.90.91.21.3-1.21.10.90.4-0.4
Pavlov. Cond. response bias1.41.73.0-0.8-1.6-0.90.9-1.7-1.5-1.7-1.61.1-1.11.11.61.7-1.61.51.10.5-0.4
Pavlov. Cond. lever latency0.30.41.70.50.6-0.10.1-0.00.10.0-0.10.7-0.80.80.1-0.60.20.20.61.3-1.3
Pavlov. Cond. magazine entry latency1.31.53.2-1.3-1.7-0.80.8-1.5-1.5-1.4-1.50.6-0.60.61.51.8-1.61.30.6-0.70.8
Pavlov. Cond. change in total contacts1.31.77.81.0-0.01.3-1.3-0.30.1-0.3-0.1-1.71.7-1.70.31.0-0.40.6-1.1-2.82.8
Pavlov. Cond. index score0.50.61.7-0.7-1.1-0.10.1-0.8-0.9-0.8-0.8-0.10.2-0.20.81.3-1.00.70.0-1.21.2
Pavlov. Cond. latency score0.60.82.1-0.8-1.2-0.20.2-1.0-1.0-1.0-0.9-0.10.2-0.21.01.4-1.10.80.1-1.31.4
Pavlov. Cond. lever contacts0.20.31.3-0.5-0.70.1-0.10.0-0.1-0.00.1-0.60.6-0.6-0.10.5-0.2-0.3-0.6-1.11.1
Pavlov. Cond. magazine entry number0.30.41.00.61.00.2-0.20.70.70.70.70.1-0.10.1-0.7-0.90.7-0.6-0.01.0-1.0
Pavlov. Cond. intertrial magazine entries0.20.22.11.01.50.4-0.4-0.20.0-0.30.1-0.10.1-0.10.3-0.0-0.00.2-0.4-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-0.7-1.0-0.20.2-0.7-0.7-0.7-0.7-0.10.1-0.10.71.1-0.90.5-0.0-1.11.1
Pavlov. Cond. response bias0.40.51.4-0.6-1.1-0.20.2-0.7-0.7-0.7-0.7-0.30.3-0.30.61.2-0.80.5-0.2-1.11.1
Time in closed arm before self-admin1.11.33.3-1.8-1.5-0.80.8-1.3-1.3-1.2-1.30.7-0.70.71.11.7-1.50.80.1-0.80.9
Time in closed arm after self-admin0.60.61.90.80.00.9-0.90.50.40.40.4-1.01.1-1.1-0.40.2-0.1-0.4-1.4-1.21.2
Time in open arm before self-admin0.40.41.00.61.00.3-0.30.80.70.70.7-0.40.3-0.3-0.7-1.01.0-0.80.10.2-0.2
Time in open arm after self-admin0.30.30.6-0.80.5-0.60.60.20.20.20.20.7-0.70.7-0.3-0.80.7-0.70.30.7-0.7
Bone: periosteal estimation0.71.54.12.01.21.9-1.90.60.90.50.5-1.61.6-1.6-0.5-0.30.70.0-1.2-1.21.2
Bone: periosteal perimeter1.82.98.02.82.12.4-2.41.21.51.21.1-2.02.0-2.0-1.1-0.91.2-0.6-1.7-1.31.3
Bone: post-yield work0.60.83.1-0.1-0.30.0-0.0-1.2-1.0-1.3-1.00.6-0.60.61.31.1-1.21.80.8-0.30.3
Progressive ratio test 1 active lever presses1.31.43.9-0.3-1.2-0.50.5-1.7-1.4-1.7-1.60.4-0.30.31.62.0-1.51.80.6-0.10.1
Progressive ratio test 1 breakpoint0.80.92.5-0.3-0.9-0.40.4-1.4-1.1-1.4-1.20.3-0.20.21.21.6-1.21.40.6-0.10.1
Progressive ratio test 1 inactive lever presses1.71.84.1-0.7-1.3-1.01.0-2.0-1.7-2.0-1.80.9-0.90.91.82.0-1.51.60.4-0.10.2
Progressive ratio test 2 active lever presses1.11.22.7-0.2-0.9-1.01.0-1.6-1.3-1.6-1.50.9-0.80.81.41.2-0.71.50.90.6-0.6
Progressive ratio test 2 breakpoint1.01.12.7-0.0-0.8-0.70.7-1.6-1.3-1.6-1.50.7-0.50.51.51.3-0.81.60.80.3-0.3
Progressive ratio test 2 inactive lever presses2.63.05.9-1.1-1.2-1.61.6-2.4-2.1-2.4-2.21.5-1.41.42.21.8-1.42.11.60.8-0.7
Incentive Sensitization - Responses0.30.30.6-0.1-0.0-0.80.8-0.4-0.4-0.4-0.30.7-0.70.70.3-0.20.40.10.50.7-0.7
Incentive Sensitization - Breakpoint0.30.30.60.00.1-0.80.8-0.4-0.4-0.4-0.30.7-0.70.70.3-0.30.50.10.50.7-0.7
Sum of active levers in priming session hrs 5-60.20.20.4-0.50.0-0.40.4-0.6-0.6-0.5-0.60.5-0.50.50.50.5-0.40.40.1-0.10.1
Progressive ratio0.20.20.8-0.10.20.2-0.2-0.6-0.3-0.4-0.3-0.40.4-0.40.50.7-0.60.4-0.2-0.90.9
Food seeking constrained by brief footshock0.10.10.30.4-0.4-0.00.0-0.50.0-0.3-0.20.10.0-0.00.40.4-0.30.50.20.5-0.5
Seeking ratio, punishment vs. effort0.10.20.60.1-0.6-0.30.3-0.2-0.2-0.3-0.40.5-0.40.40.30.2-0.20.30.30.8-0.8
Retroperitoneal fat weight4.113.622.54.73.93.9-3.94.04.44.04.1-3.73.7-3.7-3.9-3.73.6-3.4-3.6-1.31.2
Reaction time number correct0.91.34.4-1.0-0.3-1.51.5-0.1-0.40.0-0.11.4-1.31.30.0-0.70.4-0.21.52.1-2.1
Reaction time mean minus median0.00.00.20.10.40.2-0.20.10.10.0-0.0-0.0-0.00.0-0.2-0.10.4-0.2-0.4-0.40.4
Reaction time mean minus median AUC0.30.41.10.70.80.5-0.50.70.70.70.6-0.40.4-0.4-0.7-0.60.8-0.8-1.1-0.50.5
Reaction time num false alarms0.20.20.60.4-0.10.3-0.30.70.60.70.7-0.30.4-0.4-0.8-0.50.3-0.6-0.6-0.20.2
Reaction time num false alarms AUC0.10.20.50.2-0.10.1-0.10.60.50.50.6-0.30.4-0.4-0.7-0.40.2-0.5-0.3-0.00.0
Reaction time trials correct on left0.91.34.4-1.0-0.3-1.51.5-0.1-0.40.0-0.11.4-1.31.30.0-0.70.4-0.21.52.1-2.1
Reaction time trials on left1.01.44.7-1.1-0.3-1.61.6-0.1-0.5-0.0-0.11.5-1.41.40.1-0.60.3-0.21.52.2-2.2
Reaction time mean0.20.30.70.20.80.7-0.70.20.50.10.3-0.50.4-0.4-0.3-0.40.6-0.5-0.7-0.90.9
Reaction time mean AUC0.10.20.50.10.70.5-0.50.10.40.00.2-0.30.2-0.2-0.3-0.30.5-0.4-0.5-0.60.6
Median of all reaction times0.10.20.5-0.10.60.6-0.6-0.10.3-0.20.1-0.40.3-0.3-0.0-0.10.3-0.2-0.4-0.70.7
Reaction time omissions1.92.63.4-1.3-1.5-1.91.9-1.6-1.6-1.5-1.61.8-1.71.71.61.2-1.21.61.81.7-1.6
Reaction time false alarm rate0.30.40.90.50.00.6-0.60.60.70.50.6-0.80.9-0.9-0.7-0.20.0-0.5-0.9-0.80.8
Reaction time premature initiation rate0.40.62.50.60.60.8-0.8-0.1-0.10.2-0.5-0.60.7-0.70.30.6-0.20.4-1.0-1.61.6
Reaction time premature initiations0.10.10.50.20.70.2-0.2-0.0-0.10.3-0.4-0.10.1-0.10.20.10.10.2-0.4-0.60.6
Std. dev. reaction times0.60.81.80.91.30.8-0.80.80.90.80.7-0.80.8-0.8-0.8-0.81.2-0.7-1.1-0.90.9
Reaction time trials completed1.01.44.7-1.1-0.3-1.61.6-0.1-0.5-0.0-0.11.5-1.41.40.1-0.60.3-0.21.52.2-2.2
Reaction time trials AUC0.71.03.7-0.8-0.1-1.31.30.0-0.30.10.01.2-1.21.2-0.1-0.70.5-0.31.21.9-1.9
Run reversals in cocaine runway, females0.70.72.60.11.2-0.00.00.90.91.31.2-0.0-0.10.1-1.1-1.61.1-1.10.00.4-0.4
Run reversals in cocaine runway, males0.10.10.40.2-0.10.6-0.60.30.10.00.1-0.60.6-0.6-0.10.0-0.20.20.40.0-0.0
Latency to leave start box in cocaine runway0.30.40.60.70.10.6-0.60.70.70.60.6-0.70.7-0.7-0.7-0.60.7-0.6-0.40.5-0.5
Latency to leave start box in cocaine runway, F0.30.31.9-0.5-1.4-0.30.3-0.5-0.3-0.5-0.3-0.0-0.00.00.40.6-0.50.40.80.9-0.8
Latency to leave start box in cocaine runway, M1.71.63.71.61.91.1-1.11.41.51.41.1-0.90.9-0.9-1.3-1.61.5-1.4-1.30.1-0.1
Std. dev. time between licks in bursts0.30.41.3-0.6-0.30.2-0.2-0.5-0.5-0.6-0.5-0.40.3-0.30.61.1-0.90.60.3-0.91.0
Total sessions with >9 infusions0.30.41.51.20.30.6-0.6-0.6-0.2-0.6-0.5-0.50.6-0.60.50.7-0.40.8-0.6-0.60.6
Short access day 1 total inactive lever presses1.31.43.40.50.01.0-1.0-1.0-0.6-1.0-0.9-1.31.4-1.41.01.8-1.51.5-0.2-1.81.8
Short access day 10 total inactive lever presses2.22.44.01.32.01.8-1.81.31.31.31.3-1.91.9-1.9-1.3-1.01.4-1.0-1.3-1.91.9
Short access day 1 total infusions0.40.51.01.00.30.5-0.5-0.8-0.4-0.8-0.6-0.80.9-0.90.60.8-0.40.7-0.4-0.70.7
Short access day 10 total infusions0.70.72.20.9-0.60.5-0.5-1.1-0.5-1.1-0.9-0.60.8-0.81.01.5-0.91.3-0.4-0.50.5
Short access total infusions0.91.02.31.3-0.20.7-0.7-1.1-0.6-1.1-1.0-1.01.1-1.11.01.5-0.91.3-0.6-0.80.8
Short access day 1 locomotion0.60.62.10.2-0.50.1-0.1-1.1-0.8-1.1-1.0-0.10.2-0.21.01.5-1.01.0-0.2-0.70.7
Short access day 10 total locomotion0.60.72.5-0.0-0.6-0.20.2-1.0-0.9-1.0-1.10.4-0.20.21.01.6-0.80.6-0.8-1.11.1
Short access total locomotion0.91.02.71.0-0.20.9-0.9-0.7-0.3-0.7-0.5-0.80.9-0.90.71.6-0.90.7-1.3-1.61.6
One hour access (0.3 mA shock)4.65.47.9-1.8-2.8-2.32.3-2.7-2.5-2.7-2.82.1-2.02.02.52.3-2.22.52.21.8-1.8
Compulsive drug intake1.01.02.2-1.4-1.1-1.41.4-0.4-0.9-0.4-0.81.5-1.41.40.6-0.1-0.40.41.30.9-0.9
One hour access (shock baseline)0.70.81.8-0.3-1.2-0.70.7-1.3-0.9-1.3-1.10.4-0.30.31.01.2-0.91.10.50.7-0.7
Social response proportion0.20.20.7-0.4-0.5-0.40.4-0.3-0.2-0.1-0.4-0.20.2-0.20.30.8-0.40.5-0.2-0.50.5
Social responses0.91.14.0-0.7-2.0-1.11.1-0.9-1.0-0.7-1.10.7-0.70.71.11.6-1.51.30.90.2-0.2
Social time3.14.08.3-2.2-2.9-2.02.0-2.2-2.2-2.1-2.21.8-1.71.72.22.6-2.52.11.30.2-0.2
Soleus weight0.30.71.5-0.3-0.5-0.20.2-1.1-1.1-1.2-1.00.8-0.70.71.21.2-1.11.10.5-0.60.6
Bone: stiffness0.60.92.21.50.81.4-1.4-0.00.4-0.0-0.1-1.21.2-1.20.10.20.10.4-1.1-1.41.4
Tibialis anterior weight2.58.612.7-3.2-3.1-3.33.3-3.0-3.0-2.9-2.93.6-3.53.52.82.7-3.02.52.21.5-1.4
Time to tail flick, vehicle, before self-admin0.10.10.50.60.70.1-0.10.40.40.50.2-0.20.2-0.2-0.4-0.40.40.00.1-0.20.2
Time to tail flick, vehicle, after self-admin0.40.40.9-0.30.40.5-0.51.00.70.90.9-0.40.4-0.4-1.0-0.60.3-0.9-0.3-0.60.5
Time to tail flick, test, before self-admin1.01.01.9-0.8-1.2-1.11.1-0.7-0.8-0.6-0.81.4-1.41.40.70.5-1.20.70.81.2-1.2
Time to tail flick, test, after self-admin0.40.41.7-1.3-0.9-0.90.9-0.4-0.5-0.3-0.20.8-0.80.80.30.3-0.50.10.80.4-0.4
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.7-0.50.2-0.2-0.3-0.4-0.4-0.2-0.10.1-0.10.30.6-0.60.0-0.2-0.50.5
Delta time to tail flick, test, before/after SA0.20.21.1-1.1-0.1-0.70.70.20.20.20.50.3-0.30.3-0.4-0.30.4-0.60.40.2-0.2
Tibia length0.20.52.21.50.51.4-1.40.40.50.40.4-0.90.8-0.8-0.2-0.20.20.3-0.3-0.40.4
Ambulatory time before self-admin2.22.34.0-1.3-2.0-1.41.4-2.0-1.6-2.0-1.51.4-1.31.31.91.6-1.61.41.20.9-0.9
Ambulatory time after self-admin0.40.51.7-0.00.20.4-0.4-0.5-0.5-0.6-0.8-0.50.5-0.50.71.1-0.51.00.3-1.31.3
Bone: tissue strength0.40.41.10.91.00.6-0.60.50.60.50.4-0.80.8-0.8-0.5-0.50.8-0.3-0.4-0.30.3
Total heroin consumption0.80.92.5-0.5-1.6-0.90.9-0.8-1.0-0.8-0.81.1-1.11.10.80.8-1.11.00.81.0-0.9
Bone: trabecular number0.30.41.80.31.30.0-0.00.80.70.70.7-0.20.2-0.2-0.8-1.01.0-0.9-0.20.3-0.3
Bone: trabecular spacing0.40.51.40.9-0.40.8-0.8-0.6-0.4-0.6-0.5-0.20.1-0.10.81.0-0.91.2-0.1-0.80.8
Bone: trabecular thickness0.20.31.2-0.30.9-0.30.30.40.30.50.1-0.10.1-0.1-0.6-0.70.7-1.1-0.50.2-0.3
Bone: trabecular tissue density0.20.21.5-1.2-0.3-0.10.10.30.10.30.30.1-0.20.2-0.4-0.10.1-0.6-0.4-0.80.8
Water consumed over 24 hours0.00.10.40.20.70.2-0.20.10.10.0-0.1-0.20.3-0.3-0.00.1-0.20.20.1-0.20.2
Number of responses in last shaping day4.85.09.2-1.3-2.5-1.71.7-3.0-2.7-3.0-2.91.8-1.81.82.82.9-2.52.71.30.7-0.6