Hub : Genes

Sult2a6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Sult2a6 0.09 0.06 1.8e-07 0.05 0.06 0.06 0.06 1.1e-06 2.0e-07 2.2e-07 6.5e-07
2 Liver alternative TSS NM_012695.3 0.03 0.02 5.5e-03 0.01 0.01 0.01 0.01 1.5e-02 3.5e-02 1.6e-02 2.0e-02
3 Liver alternative TSS NM_012695.3 0.09 0.06 2.6e-08 0.06 0.06 0.06 0.06 9.1e-08 1.4e-07 1.9e-07 1.3e-07
4 Liver alternative TSS XM_039101066.1 0.1 0.06 3.6e-09 0.08 0.07 0.07 0.07 7.2e-09 3.5e-08 1.4e-08 1.1e-08
5 Liver intron excision ratio chr1_74911320_74912861 0.03 0.02 8.1e-03 0.02 0.01 0.01 0.01 6.1e-03 1.0e-02 1.2e-02 1.6e-02
6 Liver isoform ratio XM_039101066.1 0.47 0.18 0.0e+00 0.39 0.39 0.39 0.39 1.4e-45 4.5e-46 2.7e-45 5.9e-46
7 Liver isoform ratio NM_012695.3 0.51 0.18 0.0e+00 0.4 0.42 0.42 0.41 9.9e-48 3.5e-50 1.4e-50 2.3e-49

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.30.40.8-0.7-0.40.4-0.40.70.90.9
Area under the delay curve1.21.31.41.2-1.21.2-1.2-1.1-1.0-1.0
BMI with tail0.72.23.81.50.9-0.90.9-1.8-1.9-1.9
BMI without tail1.12.23.01.21.4-1.41.4-1.5-1.7-1.7
Body weight0.62.55.7-0.22.4-2.42.4-0.2-0.4-0.5
Weight adjusted by age1.21.41.9-1.41.1-1.21.21.11.21.1
Bone surface2.54.47.0-2.61.3-1.31.32.52.52.5
Bone volume1.83.15.1-2.30.8-0.90.92.22.32.2
Breakpoint value in progressive ratio session6.26.88.32.9-2.72.7-2.7-2.6-2.4-2.3
Number of licking bursts0.80.92.00.11.4-1.41.4-0.3-0.4-0.5
Context. condit. distance diff. score0.10.10.2-0.30.5-0.50.50.40.20.2
Locomotion velocity, session 10.50.50.9-0.8-0.30.3-0.30.90.91.0
Locomotion distance, session 12.12.74.4-2.10.7-0.70.72.12.12.1
Locomotion velocity, session 20.81.01.7-0.91.3-1.31.30.60.60.5
Locomotion distance, session 22.43.43.9-2.01.9-1.91.92.01.71.6
Locomotion velocity, session 30.10.10.2-0.30.4-0.40.40.30.20.1
Locomotion distance, session 31.31.42.5-1.50.4-0.40.41.61.61.5
Stereotopy head waving bouts, day 30.60.71.31.1-0.20.2-0.2-1.2-1.1-1.1
Stereotopy head waving duration, day 30.70.81.31.1-0.40.4-0.4-1.1-1.1-1.1
Locomotion velocity, session 70.50.60.8-0.4-0.90.9-0.90.70.60.7
Locomotion distance, session 70.10.10.3-0.3-0.10.1-0.10.50.40.4
Stereotopy head waving bouts, day 70.30.30.4-0.60.6-0.60.60.40.50.5
Stereotopy head waving duration, day 70.20.30.5-0.50.7-0.70.70.10.30.3
Locomotion velocity, session 80.10.10.4-0.40.0-0.00.00.60.50.5
Locomotion distance, session 80.91.31.9-1.21.1-1.11.11.41.01.0
Degree of sensitization distance0.40.40.70.8-0.30.3-0.3-0.7-0.8-0.8
Degree of sensitization stereotypy1.11.21.9-1.11.4-1.41.40.70.80.7
Conditioned locomotion0.00.00.1-0.10.3-0.30.3-0.1-0.0-0.0
Cocaine response after cond. corrected1.21.32.21.5-0.50.5-0.5-1.4-1.5-1.4
Cocaine response after cond. not corrected0.20.20.4-0.10.7-0.60.6-0.1-0.1-0.1
Cocaine response before conditioning6.68.010.2-3.22.8-2.82.82.82.82.6
Saline control response1.52.02.4-1.61.5-1.51.51.31.31.2
Bone: connectivity density0.10.20.4-0.6-0.20.1-0.10.50.70.7
Bone: cortical apparent density0.50.71.11.0-0.60.6-0.6-0.9-1.0-0.9
Bone: cortical area0.81.21.5-1.11.2-1.21.21.00.90.8
Bone: cortical porosity0.60.61.01.0-0.40.5-0.5-1.0-0.9-0.9
Bone: cortical porosity0.30.30.60.60.2-0.10.1-0.8-0.7-0.7
Bone: cortical thickness0.40.61.01.0-0.60.5-0.5-0.9-1.0-0.9
Bone: cortical thickness0.20.20.3-0.40.6-0.50.50.40.30.3
Bone: cortical tissue density0.50.71.01.0-0.70.6-0.6-0.9-0.9-0.9
Condit. Reinf. active minus inactive responses0.40.40.60.60.5-0.50.5-0.7-0.8-0.8
Condit. Reinf. active-inactive response ratio0.91.01.81.10.4-0.40.4-1.3-1.3-1.4
Condit. Reinf. active responses0.10.20.4-0.20.6-0.60.60.10.10.1
Condit. Reinf. inactive responses1.41.73.0-1.60.2-0.30.31.71.71.7
Incentive salience index mean0.30.30.7-0.20.8-0.80.80.0-0.0-0.1
Condit. Reinf. lever presses0.40.50.6-0.70.8-0.80.80.60.60.5
Condit. Reinf. active minus inactive responses3.34.16.5-2.51.1-1.11.12.52.52.4
Condit. Reinf. active-inactive response ratio3.03.14.8-2.21.0-1.01.02.22.12.1
Condit. Reinf. active responses3.24.47.4-2.61.1-1.11.12.72.62.5
Condit. Reinf. inactive responses0.20.30.5-0.6-0.00.0-0.00.70.70.7
Condit. Reinf. lever presses0.60.81.3-0.81.1-1.11.10.60.50.5
Condit. Reinf. lever reinforcers received4.15.79.2-3.01.4-1.41.43.02.92.8
Conditioned reinforcement - actives0.80.81.40.90.6-0.60.6-0.9-1.1-1.2
Conditioned reinforcement - inactives1.71.92.5-1.61.5-1.51.51.21.31.2
Conditioned locomotion0.60.71.30.90.4-0.40.4-1.0-1.1-1.1
Patch foraging indifference point 0 sec0.20.30.60.6-0.40.5-0.5-0.8-0.6-0.5
Patch foraging indifference point AUC0.91.12.30.21.5-1.41.4-0.5-0.7-0.8
Delay disc. indifference point, 0s delay0.70.81.5-1.10.00.0-0.01.21.21.2
Delay disc. indifference point, 16s delay2.42.43.41.8-1.31.3-1.3-1.7-1.7-1.6
Delay disc. indifference point, 2s delay0.50.50.90.6-0.90.9-0.9-0.5-0.5-0.4
Delay disc. indifference point, 24s delay1.21.22.01.4-0.40.4-0.4-1.4-1.4-1.4
Delay disc. indifference point, 4s delay0.10.10.1-0.40.4-0.30.30.30.30.3
Delay disc. indifference point, 8s delay1.21.21.91.0-1.31.4-1.4-0.9-0.8-0.7
Indifference point function ln k3.04.27.9-2.4-0.70.7-0.72.62.82.8
Indifference point function log k3.04.27.9-2.4-0.70.7-0.72.62.82.8
Patch foraging total patch changes 0 sec0.30.50.90.8-0.40.4-0.4-0.9-0.8-0.7
Patch foraging total patch changes 12 sec0.50.61.00.70.7-0.50.5-1.0-0.9-1.0
Patch foraging total patch changes 18 sec0.50.60.80.50.9-0.80.8-0.7-0.8-0.9
Patch foraging total patch changes 24 sec0.50.71.50.11.2-1.11.1-0.2-0.5-0.6
Patch foraging total patch changes 6 sec0.91.32.61.30.3-0.20.2-1.6-1.6-1.6
Patch foraging time to switch 0 sec5.58.510.83.3-2.82.8-2.8-3.0-2.9-2.7
Patch foraging water rate 0 sec2.33.75.2-1.92.2-2.32.31.61.51.4
Patch foraging water rate 12 sec1.72.64.3-2.00.9-0.90.92.12.01.9
Patch foraging water rate 18 sec0.30.40.7-0.80.3-0.40.40.80.80.8
Patch foraging water rate 24 sec0.81.22.1-1.40.2-0.30.31.41.41.4
Patch foraging water rate 6 sec6.59.511.6-3.43.1-3.13.13.12.92.7
Seeking ratio, delayed vs. immediate footshock0.70.81.2-0.8-0.70.8-0.81.01.11.1
Distance traveled before self-admin1.92.03.3-1.80.8-0.80.81.71.81.7
Distance traveled after self-admin1.21.32.4-1.4-0.30.3-0.31.51.61.6
Extensor digitorum longus weight0.83.06.5-1.02.5-2.52.50.50.40.2
Bone: elastic displacement2.02.24.31.1-2.02.1-2.1-0.8-0.7-0.6
Bone: elastic work0.10.20.3-0.4-0.40.3-0.30.40.50.5
Bone: endosteal estimation2.65.78.7-2.91.6-1.61.62.92.82.7
Bone: endosteal perimeter1.73.55.3-2.31.3-1.31.32.22.22.1
Epididymis fat weight1.33.13.91.8-2.01.9-1.9-1.6-1.5-1.4
Delta time in closed arm before/after self-admin0.10.10.1-0.20.4-0.40.40.20.10.1
Delta time in open arm before/after self-admin0.30.30.5-0.70.5-0.50.50.70.60.5
Diff in mean of infusions in LGA sessions0.60.71.40.6-1.21.2-1.2-0.4-0.3-0.3
Delay discount exponential model param1.11.21.4-1.21.0-1.11.11.11.11.0
Extinction: sum of active levers before priming0.20.20.4-0.2-0.60.6-0.60.20.40.4
Active lever presses in extinction session 60.90.91.50.90.6-0.60.6-1.1-1.2-1.2
Bone: final force1.72.83.5-1.91.7-1.71.71.61.61.5
Bone: final moment2.33.84.8-2.21.9-1.91.91.91.91.8
Food consumed during 24 hour testing period0.91.12.3-0.2-1.51.5-1.50.40.60.7
Glucose1.11.73.41.0-1.81.8-1.8-0.6-0.6-0.5
Heart weight0.71.01.2-1.01.0-1.11.11.00.80.7
Delay discount hyperbolic model param0.70.70.8-0.90.8-0.90.90.80.80.8
Intermittent access intake day 1-15 change0.10.10.2-0.20.4-0.40.40.10.10.1
Intermittent access intake escalation0.00.00.00.10.2-0.10.1-0.2-0.2-0.2
Intermittent access intake escalation 20.10.10.2-0.40.4-0.30.30.30.40.3
Intermitt. access day 1 inactive lever presses0.40.41.1-0.10.9-1.01.0-0.0-0.1-0.1
Intermitt. access day 15 inactive lever presses1.41.53.3-0.71.8-1.81.80.40.30.1
Intermitt. access escalation Index1.11.01.71.3-0.40.3-0.3-1.3-1.3-1.3
Intermittent access day 1 total infusions0.40.50.9-0.51.0-1.01.00.40.20.2
Intermittent access day 15 total infusions0.20.20.40.50.2-0.20.2-0.5-0.6-0.7
Intermittent access terminal intake (last 3 days)0.00.00.10.10.3-0.20.2-0.1-0.2-0.2
Intermittent access total infusions0.10.10.3-0.10.6-0.60.60.0-0.1-0.1
Intermittent access day 1 locomotion0.10.10.2-0.1-0.40.5-0.50.20.20.2
Intermittent access day 15 total locomotion0.50.50.60.7-0.70.8-0.8-0.7-0.6-0.6
Intermittent access total locomotion0.00.00.0-0.2-0.00.1-0.10.20.20.2
Intermittent access standard deviation1.21.32.31.20.5-0.50.5-1.5-1.5-1.5
Left kidney weight5.916.730.6-3.45.5-5.45.42.62.31.9
Right kidney weight3.18.617.2-2.14.1-4.14.11.61.31.0
Cocaine induced anxiety1.82.13.9-1.7-0.50.5-0.51.82.01.9
Post-drug Anxiety0.20.20.4-0.5-0.10.1-0.10.60.50.5
Baseline Anxiety0.91.01.81.3-0.20.2-0.2-1.3-1.4-1.3
Tail length0.41.32.0-1.11.4-1.31.30.90.80.7
Length with tail1.14.25.2-2.32.2-2.12.12.01.91.7
Length without tail0.81.72.3-1.51.3-1.21.21.31.31.2
Times rat made contact with spout0.20.20.50.2-0.70.7-0.7-0.1-0.00.0
Lifetime Intake0.10.10.30.10.5-0.50.5-0.1-0.2-0.3
Liver weight, left4.67.316.2-0.14.0-4.04.0-0.6-1.0-1.2
Liver weight, right1.11.93.90.22.0-2.02.0-0.5-0.7-0.8
Locomotor activity0.40.61.20.31.1-1.01.0-0.7-0.7-0.7
Locomotor testing distance0.10.20.6-0.10.8-0.70.7-0.2-0.1-0.1
Locomotor testing rearing2.74.29.0-1.33.0-3.03.00.80.70.5
Locomotion in novel chamber2.63.26.51.2-2.52.5-2.5-0.9-0.7-0.6
Locomotion in novel chamber post-restriction0.50.61.30.6-1.11.1-1.1-0.5-0.3-0.3
Fecal boli incidents, locomotor time 10.20.20.4-0.50.0-0.00.00.60.60.6
Change in fecal boli incidents, locomotor task1.91.82.41.5-1.31.3-1.3-1.4-1.3-1.3
Time >=10cm from walls, locomotor time 10.80.81.11.0-0.80.8-0.8-1.0-0.9-0.9
Bouts of movement, locomotor time 10.60.71.1-0.8-0.60.6-0.61.01.01.1
Total resting periods, locomotor time 10.70.81.5-0.2-1.21.2-1.20.40.50.6
Rest time, locomotor task time 11.41.62.9-1.60.2-0.20.21.71.71.7
Distance moved, locomotor task time 10.50.51.00.90.1-0.10.1-1.0-1.0-1.0
Vertical activity count, locomotor time 10.70.81.31.1-0.40.4-0.4-1.2-1.1-1.1
Time >=10cm from walls, locomotor time 20.60.61.01.0-0.40.4-0.4-1.0-1.0-1.0
Bouts of movement, locomotor time 20.70.81.7-0.0-1.31.3-1.30.30.30.4
Total resting periods, locomotor time 20.91.01.9-0.2-1.41.4-1.40.60.60.7
Rest time, locomotor task time 20.60.70.9-0.6-0.80.8-0.80.80.90.9
Distance moved, locomotor task time 20.40.51.1-0.21.1-1.11.1-0.1-0.2-0.2
Vertical activity count, locomotor time 20.20.20.5-0.10.7-0.70.7-0.1-0.2-0.2
Light reinforcement 10.50.91.3-0.91.1-1.11.10.90.70.7
Light reinforcement 20.50.71.20.80.6-0.60.6-0.9-1.1-1.1
Bone: marrow area2.75.98.9-3.01.6-1.61.62.92.92.7
Bone: maximum diameter1.93.66.4-1.52.5-2.52.51.31.00.9
Bone: maximum force1.52.63.6-1.91.5-1.51.51.71.71.6
Bone: maximum moment2.03.54.9-2.21.6-1.71.72.02.01.9
Mean time between licks in bursts0.30.40.70.8-0.20.2-0.2-0.8-0.9-0.9
Mean num. licks in bursts1.21.53.2-0.0-1.81.8-1.80.30.50.6
Cd content in liver0.30.30.5-0.70.1-0.10.10.60.70.7
Co content in liver0.40.51.00.1-1.01.0-1.00.10.20.3
Cu content in liver0.70.81.2-0.91.1-1.11.10.60.70.7
Fe content in liver0.20.20.4-0.10.7-0.70.7-0.0-0.0-0.1
K content in liver1.11.12.3-0.71.5-1.51.50.40.30.3
Mg content in liver0.50.51.00.21.0-1.01.0-0.4-0.4-0.5
Mn content in liver0.60.60.80.60.8-0.80.8-0.7-0.9-0.9
Na content in liver0.60.61.01.0-0.40.4-0.4-1.0-1.0-1.0
Rb content in liver0.50.60.9-0.70.9-0.90.90.60.60.5
Se content in liver2.43.03.91.31.7-1.71.7-1.8-1.9-2.0
Sr content in liver2.32.13.31.8-0.80.8-0.8-1.8-1.8-1.7
Zn content in liver0.40.50.80.60.5-0.50.5-0.8-0.8-0.9
Bone: minimum diameter3.36.29.1-3.01.9-1.91.92.92.82.7
Time in familiar zone, hab. session 13.43.15.1-2.20.9-0.90.92.32.22.2
Time in novel zone, hab. session 11.71.63.01.50.2-0.20.2-1.7-1.7-1.7
Total zone transitions, hab. session 11.92.74.3-2.10.9-0.90.92.02.02.0
Total locomotion distance, hab. session 10.60.81.6-1.1-0.20.2-0.21.21.21.2
Locomotion velocity, hab. session 10.50.81.1-0.8-0.70.7-0.70.91.01.1
Time in familiar zone, hab. session 20.70.71.2-1.10.3-0.30.31.11.11.1
Time in novel zone, hab. session 20.50.50.90.80.0-0.00.0-0.9-0.9-0.9
Total zone transitions, hab. session 22.93.85.7-2.41.5-1.51.52.22.22.1
Total locomotion distance, hab. session 20.20.30.5-0.5-0.40.4-0.40.60.70.7
Locomotion velocity, hab. session 20.20.20.4-0.5-0.30.3-0.30.60.60.6
Novel to familiar place preference ratio0.30.30.7-0.30.9-0.90.90.10.10.1
Novelty place preference0.40.40.8-0.50.9-0.90.90.40.30.3
Time in novel zone, NPP test0.50.50.9-0.50.9-0.90.90.40.40.3
Total zone transitions, NPP test0.40.50.7-0.70.8-0.80.80.60.60.5
Total locomotion distance, NPP test0.10.10.2-0.20.4-0.40.40.20.10.1
Locomotion velocity, NPP test0.10.20.3-0.50.5-0.50.50.40.40.3
Intraocular pressure0.10.10.3-0.3-0.20.2-0.20.60.40.5
Delta distance traveled before/after self-admin0.40.40.80.6-0.90.9-0.9-0.3-0.4-0.4
Delta ambulatory time before/after self-admin0.50.61.00.7-1.01.0-1.0-0.4-0.5-0.5
Parametrial fat weight4.48.612.73.6-2.22.2-2.2-3.4-3.3-3.2
Pavlov. Cond. lever latency0.30.30.80.2-0.90.9-0.9-0.0-0.00.0
Pavlov. Cond. magazine entry latency0.40.50.70.50.8-0.80.8-0.6-0.8-0.8
Pavlov. Cond. change in total contacts0.10.10.10.3-0.30.3-0.3-0.4-0.2-0.2
Pavlov. Cond. index score0.40.51.00.31.0-1.01.0-0.4-0.5-0.6
Pavlov. Cond. latency score0.20.30.40.40.6-0.60.6-0.5-0.6-0.6
Pavlov. Cond. lever contacts0.30.40.9-0.01.0-0.90.9-0.2-0.2-0.3
Pavlov. Cond. magazine entry number0.30.30.7-0.0-0.80.9-0.90.10.30.3
Pavlov. Cond. intertrial magazine entries0.20.30.4-0.5-0.50.5-0.50.40.60.7
Pavlov. Cond. lever-magazine prob. diff.0.50.61.10.31.1-1.11.1-0.5-0.6-0.6
Pavlov. Cond. response bias1.11.33.0-0.11.7-1.71.7-0.2-0.4-0.5
Pavlov. Cond. lever latency0.10.20.3-0.5-0.10.1-0.10.60.60.6
Pavlov. Cond. magazine entry latency0.70.81.31.1-0.40.4-0.4-1.1-1.1-1.1
Pavlov. Cond. change in total contacts0.40.51.0-0.9-0.10.1-0.11.01.01.0
Pavlov. Cond. index score0.00.10.10.30.1-0.10.1-0.3-0.3-0.3
Pavlov. Cond. latency score0.20.30.50.7-0.30.3-0.3-0.7-0.7-0.6
Pavlov. Cond. lever contacts0.10.20.5-0.20.7-0.70.70.10.10.0
Pavlov. Cond. magazine entry number0.30.40.5-0.60.7-0.70.70.50.50.5
Pavlov. Cond. intertrial magazine entries3.03.96.0-2.41.2-1.21.22.42.42.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.10.3-0.30.3-0.2-0.2-0.2
Pavlov. Cond. response bias0.30.40.5-0.70.7-0.70.70.60.60.6
Time in closed arm before self-admin0.10.10.20.30.2-0.20.2-0.4-0.4-0.4
Time in closed arm after self-admin0.10.10.10.30.0-0.00.0-0.3-0.4-0.3
Time in open arm before self-admin0.20.20.3-0.5-0.10.1-0.10.50.60.6
Time in open arm after self-admin0.20.30.5-0.70.1-0.10.10.70.70.7
Bone: periosteal estimation2.34.96.9-2.61.8-1.81.82.52.42.3
Bone: periosteal perimeter2.64.36.3-2.51.6-1.61.62.42.32.2
Bone: post-yield work1.11.52.4-1.60.7-0.70.71.41.51.5
Progressive ratio test 1 active lever presses1.81.92.8-1.71.0-1.01.01.61.61.5
Progressive ratio test 1 breakpoint1.61.62.3-1.51.0-1.01.01.51.41.4
Progressive ratio test 1 inactive lever presses3.84.25.7-2.12.3-2.42.41.81.71.5
Progressive ratio test 2 active lever presses0.10.10.2-0.00.4-0.40.4-0.0-0.1-0.2
Progressive ratio test 2 breakpoint0.10.10.2-0.10.5-0.50.50.1-0.0-0.1
Progressive ratio test 2 inactive lever presses1.01.21.7-1.11.3-1.31.30.90.80.7
Incentive Sensitization - Responses0.10.10.2-0.20.5-0.40.40.10.10.0
Incentive Sensitization - Breakpoint0.10.10.10.00.4-0.30.3-0.1-0.2-0.2
Sum of active levers in priming session hrs 5-61.91.93.11.2-1.81.8-1.8-1.0-0.8-0.8
Progressive ratio0.10.10.2-0.3-0.00.1-0.10.30.40.4
Food seeking constrained by brief footshock2.12.64.6-1.6-1.01.0-1.01.92.12.1
Seeking ratio, punishment vs. effort0.60.71.2-0.9-0.60.5-0.51.01.11.1
Retroperitoneal fat weight4.414.521.44.6-2.92.9-2.9-4.3-4.3-4.2
Reaction time number correct0.91.33.0-0.51.7-1.71.70.20.1-0.0
Reaction time mean minus median0.20.30.60.1-0.80.8-0.80.00.00.1
Reaction time mean minus median AUC0.00.00.0-0.1-0.10.1-0.10.10.10.1
Reaction time num false alarms2.02.86.2-0.02.5-2.52.5-0.4-0.6-0.8
Reaction time num false alarms AUC1.62.24.90.02.2-2.22.2-0.5-0.6-0.7
Reaction time trials correct on left0.91.33.0-0.51.7-1.71.70.20.1-0.0
Reaction time trials on left0.91.33.1-0.51.8-1.71.70.20.1-0.0
Reaction time mean0.71.02.20.2-1.51.5-1.5-0.20.10.3
Reaction time mean AUC0.91.22.50.7-1.61.6-1.6-0.7-0.4-0.2
Median of all reaction times0.70.92.10.3-1.41.4-1.4-0.30.00.2
Reaction time omissions0.10.10.20.20.4-0.40.4-0.1-0.3-0.3
Reaction time false alarm rate0.30.40.60.40.8-0.80.8-0.5-0.6-0.7
Reaction time premature initiation rate1.11.43.20.6-1.71.8-1.8-0.4-0.2-0.1
Reaction time premature initiations0.30.40.90.5-0.80.9-0.9-0.4-0.3-0.3
Std. dev. reaction times0.30.51.20.3-1.11.0-1.0-0.2-0.00.0
Reaction time trials completed0.91.33.1-0.51.8-1.71.70.20.1-0.0
Reaction time trials AUC1.11.63.6-0.41.9-1.91.90.1-0.0-0.1
Run reversals in cocaine runway, females1.71.62.71.1-1.71.6-1.6-0.8-0.8-0.7
Run reversals in cocaine runway, males0.70.71.4-0.61.2-1.11.10.50.40.3
Latency to leave start box in cocaine runway0.20.30.60.2-0.70.8-0.8-0.3-0.1-0.1
Latency to leave start box in cocaine runway, F0.10.10.30.3-0.50.5-0.5-0.3-0.2-0.2
Latency to leave start box in cocaine runway, M0.30.20.3-0.60.5-0.50.50.50.50.5
Std. dev. time between licks in bursts0.50.61.1-0.51.1-1.11.10.40.30.2
Total sessions with >9 infusions1.71.93.2-1.21.8-1.81.81.00.80.7
Short access day 1 total inactive lever presses0.50.61.4-0.11.2-1.21.2-0.1-0.2-0.2
Short access day 10 total inactive lever presses0.10.10.3-0.0-0.50.5-0.50.00.10.2
Short access day 1 total infusions0.30.30.4-0.50.6-0.60.60.50.40.4
Short access day 10 total infusions0.70.81.60.21.3-1.31.3-0.3-0.6-0.6
Short access total infusions0.10.20.30.50.2-0.20.2-0.4-0.6-0.6
Short access day 1 locomotion0.30.30.4-0.70.6-0.60.60.60.50.5
Short access day 10 total locomotion0.40.40.8-0.2-0.80.9-0.90.40.40.5
Short access total locomotion0.10.10.20.2-0.50.5-0.50.0-0.1-0.1
One hour access (0.3 mA shock)0.10.10.2-0.4-0.10.1-0.10.30.40.4
Compulsive drug intake0.30.30.5-0.70.2-0.20.20.50.70.7
One hour access (shock baseline)0.40.40.70.60.6-0.60.6-0.7-0.8-0.8
Social response proportion0.40.40.90.10.9-1.01.0-0.3-0.4-0.4
Social responses2.22.94.7-1.52.1-2.22.21.31.11.0
Social time2.73.66.3-2.40.8-0.80.82.52.42.3
Soleus weight0.10.30.7-0.00.8-0.80.8-0.2-0.2-0.2
Bone: stiffness1.93.04.5-1.72.1-2.12.11.41.31.2
Tibialis anterior weight1.13.74.21.32.1-2.02.0-1.8-2.0-2.0
Time to tail flick, vehicle, before self-admin0.20.30.5-0.60.1-0.10.10.70.70.6
Time to tail flick, vehicle, after self-admin0.10.20.20.4-0.40.4-0.4-0.3-0.4-0.3
Time to tail flick, test, before self-admin1.91.93.4-1.6-0.50.5-0.51.81.81.8
Time to tail flick, test, after self-admin0.00.00.00.10.1-0.10.1-0.2-0.1-0.1
Delta time to tail flick, vehicle, before/after SA0.50.51.00.9-0.20.2-0.2-0.9-1.0-1.0
Delta time to tail flick, test, before/after SA0.90.81.61.10.2-0.20.2-1.2-1.2-1.2
Tibia length3.710.512.4-3.53.4-3.43.43.03.02.7
Ambulatory time before self-admin2.12.23.5-1.90.7-0.70.71.81.91.8
Ambulatory time after self-admin1.41.62.8-1.4-0.50.5-0.51.61.71.7
Bone: tissue strength0.00.00.10.1-0.20.3-0.3-0.1-0.0-0.0
Total heroin consumption0.80.91.41.2-0.60.6-0.6-1.2-1.1-1.1
Bone: trabecular number0.20.40.6-0.6-0.50.5-0.50.60.70.8
Bone: trabecular spacing0.10.10.10.20.4-0.40.4-0.2-0.4-0.4
Bone: trabecular thickness0.10.10.10.00.4-0.40.4-0.1-0.1-0.2
Bone: trabecular tissue density2.13.05.22.2-0.50.5-0.5-2.3-2.3-2.2
Water consumed over 24 hours0.60.71.4-1.0-0.10.1-0.11.11.11.2
Number of responses in last shaping day0.30.30.40.40.5-0.60.6-0.5-0.6-0.6