Hub : Genes

Stk38

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Stk38 0.04 0.03 9.9e-05 0.05 0.04 0.04 0.05 1.5e-05 8.1e-05 1.3e-04 4.0e-05
2 NAcc mRNA stability Stk38 0.03 0.02 1.3e-03 0.02 0.01 0 0.01 1.6e-03 9.5e-03 7.6e-02 1.3e-02
3 Adipose gene expression Stk38 0.02 0.02 3.6e-03 0 0.01 0 0 9.2e-02 1.1e-02 3.5e-01 1.0e-01
4 IL alternative TSS XM_039098823.1 0.11 0.09 9.5e-03 0.03 0.04 -0.01 0.02 6.4e-02 4.3e-02 4.9e-01 1.3e-01
5 BLA gene expression Stk38 0.07 0.06 6.2e-04 0.05 0.06 0.04 0.04 1.4e-03 5.6e-04 2.4e-03 1.8e-03
6 Liver intron excision ratio chr20_7061807_7067531 0.06 0.08 3.4e-03 0 0.01 -0 0 1.8e-01 3.6e-02 9.6e-01 1.4e-01
7 IL mRNA stability Stk38 0.16 0.12 7.8e-04 0.12 0.11 0.1 0.1 6.9e-04 1.3e-03 1.8e-03 2.1e-03
8 Liver intron excision ratio chr20_7061807_7062476 0.04 0.04 2.4e-04 0.01 0.01 0 0 3.9e-02 5.7e-02 3.5e-01 2.1e-01
9 Adipose mRNA stability Stk38 0.03 0.03 4.4e-04 0.03 0.03 0.02 0.02 3.6e-04 8.4e-04 3.4e-03 9.1e-04
10 Liver mRNA stability Stk38 0.2 0.16 3.3e-07 0.06 0.06 0.06 0.06 3.1e-07 1.5e-07 5.9e-07 5.5e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.50.91.20.91.1-0.90.9-0.9-1.00.9-0.80.9-1.1
Area under the delay curve0.70.71.5-0.5-1.21.0-0.90.80.8-1.10.6-0.90.4
BMI with tail1.75.67.2-2.0-2.72.4-2.52.42.3-2.52.4-2.22.1
BMI without tail1.22.43.1-1.5-1.71.6-1.61.61.6-1.71.5-1.21.5
Body weight6.226.129.7-5.5-5.35.2-5.25.15.0-5.25.3-5.04.3
Weight adjusted by age0.80.91.4-0.9-1.01.1-1.00.90.8-0.91.2-1.10.4
Bone surface0.00.00.10.10.30.00.0-0.0-0.00.10.10.2-0.2
Bone volume0.00.00.1-0.0-0.00.2-0.10.10.1-0.10.2-0.0-0.1
Breakpoint value in progressive ratio session0.20.20.30.50.5-0.60.5-0.5-0.50.5-0.50.5-0.3
Number of licking bursts0.50.61.01.01.0-0.80.8-0.7-0.70.8-0.70.8-0.3
Context. condit. distance diff. score0.40.51.01.00.6-0.70.6-0.7-0.70.6-0.80.9-0.6
Locomotion velocity, session 10.80.91.41.20.7-0.80.9-0.9-1.00.7-0.81.1-1.2
Locomotion distance, session 13.64.65.32.12.1-2.12.1-2.1-2.12.2-2.12.3-2.1
Locomotion velocity, session 20.40.51.61.30.6-0.60.6-0.5-0.50.6-0.51.1-0.3
Locomotion distance, session 20.91.21.50.91.0-1.11.1-1.1-1.21.1-1.11.1-1.2
Locomotion velocity, session 30.50.50.8-0.2-0.70.8-0.80.80.8-0.70.9-0.40.9
Locomotion distance, session 30.30.31.01.00.5-0.50.5-0.5-0.50.5-0.50.8-0.3
Stereotopy head waving bouts, day 32.02.42.6-1.6-1.61.5-1.51.51.5-1.61.5-1.61.4
Stereotopy head waving duration, day 30.10.10.3-0.3-0.30.4-0.30.30.3-0.20.3-0.50.0
Locomotion velocity, session 70.10.10.40.2-0.0-0.00.1-0.2-0.20.1-0.10.1-0.7
Locomotion distance, session 70.91.12.30.90.8-0.91.0-1.1-1.20.9-1.00.9-1.5
Stereotopy head waving bouts, day 70.50.60.9-0.3-0.70.8-0.80.80.8-0.80.7-0.71.0
Stereotopy head waving duration, day 71.31.62.1-0.7-1.11.3-1.31.31.4-1.31.3-1.21.5
Locomotion velocity, session 80.00.00.10.3-0.2-0.00.0-0.1-0.10.2-0.10.0-0.2
Locomotion distance, session 80.91.31.51.11.2-1.21.1-1.1-1.11.2-1.21.2-1.0
Degree of sensitization distance0.10.10.4-0.4-0.0-0.10.1-0.2-0.20.0-0.1-0.3-0.6
Degree of sensitization stereotypy0.00.10.30.50.00.1-0.10.10.2-0.10.10.00.4
Conditioned locomotion2.93.43.9-1.8-1.81.8-1.81.91.9-1.81.9-1.82.0
Cocaine response after cond. corrected0.60.60.8-0.9-0.90.8-0.80.80.8-0.60.7-0.70.9
Cocaine response after cond. not corrected0.60.70.9-1.0-1.00.8-0.80.80.8-0.70.7-0.80.9
Cocaine response before conditioning0.00.00.1-0.3-0.10.1-0.10.10.1-0.30.1-0.4-0.0
Saline control response0.70.91.4-1.2-1.10.9-0.90.90.9-1.00.9-1.10.7
Bone: connectivity density0.50.81.50.81.2-0.70.8-0.8-0.90.9-0.71.0-1.1
Bone: cortical apparent density0.10.10.5-0.6-0.10.1-0.10.20.20.00.2-0.70.3
Bone: cortical area0.10.20.4-0.3-0.60.6-0.60.50.4-0.60.4-0.20.2
Bone: cortical porosity0.00.00.20.10.10.00.1-0.1-0.2-0.00.00.3-0.5
Bone: cortical porosity0.10.10.40.10.1-0.00.1-0.2-0.20.0-0.10.2-0.6
Bone: cortical thickness0.10.20.50.50.2-0.40.4-0.5-0.50.3-0.50.6-0.7
Bone: cortical thickness0.00.00.1-0.1-0.30.1-0.10.10.1-0.20.10.10.1
Bone: cortical tissue density0.10.20.6-0.7-0.20.2-0.20.30.3-0.10.3-0.80.4
Condit. Reinf. active minus inactive responses1.01.22.01.31.0-0.91.0-1.1-1.11.0-0.90.9-1.4
Condit. Reinf. active-inactive response ratio0.10.10.20.40.4-0.20.2-0.3-0.30.3-0.20.2-0.3
Condit. Reinf. active responses0.20.30.70.60.5-0.40.5-0.5-0.60.4-0.30.2-0.9
Condit. Reinf. inactive responses0.10.10.40.20.3-0.40.4-0.4-0.40.3-0.30.1-0.6
Incentive salience index mean0.40.51.01.00.7-0.50.6-0.7-0.70.6-0.50.4-1.0
Condit. Reinf. lever presses0.10.10.30.60.4-0.20.2-0.3-0.30.2-0.20.1-0.5
Condit. Reinf. active minus inactive responses0.70.80.90.91.0-0.90.9-0.9-0.90.9-0.80.8-0.9
Condit. Reinf. active-inactive response ratio0.30.30.50.40.7-0.60.6-0.5-0.50.5-0.50.5-0.5
Condit. Reinf. active responses0.60.91.11.10.9-0.90.9-0.9-1.00.9-0.90.8-1.0
Condit. Reinf. inactive responses0.00.10.2-0.1-0.30.2-0.20.20.2-0.30.2-0.50.1
Condit. Reinf. lever presses3.75.05.62.32.0-2.32.2-2.3-2.32.2-2.42.2-2.2
Condit. Reinf. lever reinforcers received1.42.02.61.61.3-1.41.4-1.4-1.41.3-1.41.3-1.5
Conditioned reinforcement - actives0.60.60.8-0.8-0.90.8-0.70.60.5-0.80.8-0.90.0
Conditioned reinforcement - inactives0.10.10.1-0.00.3-0.30.3-0.3-0.30.2-0.30.1-0.1
Conditioned locomotion0.50.61.0-0.9-1.00.9-0.80.70.6-0.90.8-0.8-0.1
Patch foraging indifference point 0 sec0.40.61.0-1.0-0.80.7-0.70.80.8-0.70.6-1.00.8
Patch foraging indifference point AUC0.00.00.20.40.1-0.10.1-0.1-0.10.2-0.20.20.1
Delay disc. indifference point, 0s delay0.00.00.20.1-0.40.3-0.20.10.1-0.20.10.1-0.2
Delay disc. indifference point, 16s delay0.20.20.4-0.5-0.60.5-0.40.40.3-0.50.5-0.60.1
Delay disc. indifference point, 2s delay0.20.20.70.40.1-0.30.4-0.5-0.50.2-0.60.4-0.9
Delay disc. indifference point, 24s delay2.32.22.8-1.5-1.71.6-1.61.41.4-1.61.5-1.60.9
Delay disc. indifference point, 4s delay1.01.01.7-0.6-1.31.1-1.11.11.0-1.20.7-1.01.0
Delay disc. indifference point, 8s delay1.61.62.8-0.7-1.71.4-1.41.31.2-1.61.1-1.30.8
Indifference point function ln k0.10.20.50.70.4-0.40.4-0.4-0.40.4-0.40.3-0.4
Indifference point function log k0.10.20.50.70.4-0.40.4-0.4-0.40.4-0.40.3-0.4
Patch foraging total patch changes 0 sec0.40.61.0-0.9-0.80.6-0.70.70.7-0.70.6-1.00.8
Patch foraging total patch changes 12 sec0.00.00.20.2-0.1-0.10.00.00.10.0-0.20.10.4
Patch foraging total patch changes 18 sec0.91.11.7-1.1-1.20.9-1.01.01.1-0.90.8-1.31.3
Patch foraging total patch changes 24 sec0.30.30.60.40.4-0.70.6-0.6-0.60.6-0.80.3-0.4
Patch foraging total patch changes 6 sec0.10.10.4-0.6-0.30.2-0.30.30.3-0.20.1-0.30.5
Patch foraging time to switch 0 sec1.01.51.7-1.2-1.21.3-1.31.21.2-1.21.3-1.21.1
Patch foraging water rate 0 sec0.10.20.40.20.4-0.60.6-0.5-0.50.6-0.50.2-0.4
Patch foraging water rate 12 sec0.10.10.20.40.2-0.50.4-0.4-0.40.4-0.40.4-0.2
Patch foraging water rate 18 sec0.30.40.60.10.7-0.80.8-0.7-0.70.7-0.70.4-0.7
Patch foraging water rate 24 sec0.20.30.60.40.6-0.70.6-0.6-0.50.6-0.70.5-0.1
Patch foraging water rate 6 sec0.10.20.30.20.3-0.50.5-0.4-0.40.3-0.50.4-0.2
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.3-0.10.0-0.20.30.3-0.10.1-0.10.8
Distance traveled before self-admin1.21.33.0-1.0-1.10.9-1.01.11.2-1.00.9-1.11.7
Distance traveled after self-admin0.30.31.3-0.6-0.20.2-0.30.50.6-0.30.5-0.51.1
Extensor digitorum longus weight0.20.70.80.80.7-0.90.9-0.9-0.90.9-0.80.7-0.8
Bone: elastic displacement0.10.10.30.30.2-0.10.2-0.3-0.30.2-0.20.1-0.6
Bone: elastic work0.00.00.20.1-0.20.1-0.1-0.0-0.1-0.10.0-0.2-0.4
Bone: endosteal estimation3.16.87.5-2.4-2.62.7-2.72.72.7-2.62.6-2.42.5
Bone: endosteal perimeter1.73.64.5-1.9-1.71.9-2.02.02.0-1.71.9-1.72.1
Epididymis fat weight1.43.23.7-1.9-1.91.8-1.81.71.7-1.91.9-1.61.4
Delta time in closed arm before/after self-admin1.71.62.1-1.5-1.31.2-1.21.21.2-1.31.2-1.41.2
Delta time in open arm before/after self-admin0.90.91.21.00.9-0.90.9-0.9-0.90.9-1.01.1-1.0
Diff in mean of infusions in LGA sessions0.80.91.20.71.1-1.01.0-1.0-1.01.1-0.90.8-0.9
Delay discount exponential model param0.60.61.20.51.1-0.90.9-0.7-0.71.0-0.50.8-0.4
Extinction: sum of active levers before priming0.20.20.30.50.1-0.50.5-0.4-0.40.4-0.50.4-0.3
Active lever presses in extinction session 60.10.10.3-0.3-0.10.2-0.1-0.0-0.10.00.1-0.3-0.6
Bone: final force4.06.57.2-2.5-2.62.7-2.72.62.6-2.52.6-2.42.3
Bone: final moment3.35.36.3-2.2-2.52.4-2.42.32.3-2.42.3-2.12.0
Food consumed during 24 hour testing period0.40.50.7-0.8-0.70.7-0.70.70.7-0.80.7-0.80.7
Glucose0.10.10.30.50.00.00.0-0.1-0.2-0.0-0.10.5-0.5
Heart weight2.73.94.81.72.2-1.91.9-2.0-2.01.9-2.02.0-2.1
Delay discount hyperbolic model param0.30.40.90.30.9-0.70.7-0.6-0.50.8-0.30.6-0.2
Intermittent access intake day 1-15 change1.11.01.3-0.9-1.01.0-1.01.01.0-1.01.1-1.11.1
Intermittent access intake escalation1.71.72.2-1.2-1.31.3-1.31.31.3-1.21.4-1.51.4
Intermittent access intake escalation 20.00.00.00.10.1-0.00.10.00.00.10.1-0.20.0
Intermitt. access day 1 inactive lever presses0.00.00.1-0.00.2-0.30.2-0.2-0.10.2-0.20.10.2
Intermitt. access day 15 inactive lever presses1.71.92.3-1.5-1.31.2-1.31.41.4-1.31.4-1.51.5
Intermitt. access escalation Index0.50.51.01.00.8-0.70.6-0.6-0.50.7-0.70.6-0.3
Intermittent access day 1 total infusions0.40.51.50.50.4-0.50.6-0.7-0.80.5-0.40.8-1.2
Intermittent access day 15 total infusions0.10.10.2-0.3-0.40.4-0.30.30.2-0.40.5-0.3-0.1
Intermittent access terminal intake (last 3 days)0.20.20.4-0.4-0.60.5-0.40.40.3-0.50.7-0.4-0.1
Intermittent access total infusions0.10.10.60.00.1-0.10.2-0.3-0.40.10.00.2-0.8
Intermittent access day 1 locomotion0.20.20.4-0.7-0.50.4-0.40.40.4-0.50.5-0.30.2
Intermittent access day 15 total locomotion5.86.27.3-2.7-2.52.4-2.42.42.5-2.52.6-2.52.4
Intermittent access total locomotion2.22.53.4-1.8-1.61.5-1.51.51.5-1.71.6-1.51.3
Intermittent access standard deviation1.11.11.6-1.3-1.11.0-1.01.01.0-1.01.1-1.11.1
Left kidney weight3.29.012.6-3.5-2.93.0-2.92.92.9-2.83.1-3.22.5
Right kidney weight4.011.113.6-3.7-3.43.4-3.43.33.3-3.33.4-3.23.0
Cocaine induced anxiety0.00.00.10.20.1-0.20.1-0.00.00.1-0.10.20.3
Post-drug Anxiety0.20.20.30.50.5-0.50.5-0.4-0.40.5-0.40.5-0.2
Baseline Anxiety0.30.30.50.30.6-0.60.6-0.6-0.60.6-0.60.5-0.7
Tail length1.34.06.5-2.6-1.92.0-1.91.91.9-2.12.0-2.01.7
Length with tail2.69.614.1-3.7-2.93.1-3.03.03.0-3.13.2-3.22.5
Length without tail1.94.26.1-2.5-2.02.0-2.02.01.9-1.92.1-2.31.6
Times rat made contact with spout2.63.03.51.61.9-1.81.8-1.8-1.81.7-1.71.7-1.7
Lifetime Intake0.10.10.2-0.2-0.30.3-0.10.1-0.0-0.30.4-0.2-0.5
Liver weight, left5.89.39.8-2.9-3.13.0-3.13.13.1-3.13.1-3.13.0
Liver weight, right2.94.96.1-2.0-2.32.1-2.22.22.3-2.12.3-2.12.5
Locomotor activity0.20.31.2-0.2-0.70.4-0.50.50.6-0.50.4-0.21.1
Locomotor testing distance0.10.10.40.4-0.3-0.1-0.00.10.1-0.2-0.10.40.6
Locomotor testing rearing1.11.72.6-1.3-1.41.2-1.31.31.3-1.41.2-1.01.6
Locomotion in novel chamber0.60.81.41.10.5-0.90.8-0.9-0.90.7-0.91.2-0.8
Locomotion in novel chamber post-restriction2.02.43.4-1.5-1.81.5-1.61.51.5-1.61.5-1.61.4
Fecal boli incidents, locomotor time 10.00.00.1-0.3-0.10.1-0.0-0.0-0.1-0.1-0.10.1-0.3
Change in fecal boli incidents, locomotor task0.20.10.60.8-0.50.2-0.30.30.3-0.30.10.10.5
Time >=10cm from walls, locomotor time 11.81.82.9-1.2-1.31.2-1.31.41.4-1.11.3-1.41.7
Bouts of movement, locomotor time 10.10.20.30.20.5-0.50.4-0.4-0.30.5-0.60.3-0.0
Total resting periods, locomotor time 10.00.00.1-0.20.2-0.20.1-0.1-0.00.1-0.3-0.10.2
Rest time, locomotor task time 10.10.10.1-0.3-0.30.3-0.30.30.3-0.30.2-0.00.2
Distance moved, locomotor task time 10.20.20.3-0.1-0.40.4-0.40.40.4-0.30.5-0.50.5
Vertical activity count, locomotor time 10.60.70.9-0.5-0.80.8-0.80.80.8-0.71.0-0.90.9
Time >=10cm from walls, locomotor time 24.85.16.3-2.0-2.52.5-2.42.32.2-2.42.3-1.91.8
Bouts of movement, locomotor time 20.20.30.7-0.7-0.20.3-0.40.50.6-0.30.3-0.60.8
Total resting periods, locomotor time 20.00.00.1-0.10.3-0.20.1-0.00.00.2-0.2-0.00.3
Rest time, locomotor task time 20.00.00.3-0.1-0.0-0.1-0.00.10.2-0.1-0.3-0.10.6
Distance moved, locomotor task time 22.12.43.4-1.4-1.61.7-1.61.61.5-1.61.8-1.61.0
Vertical activity count, locomotor time 21.31.42.2-1.4-1.01.3-1.21.21.1-1.11.5-1.20.5
Light reinforcement 12.13.95.6-1.8-1.91.9-2.02.02.1-2.11.9-1.62.4
Light reinforcement 22.53.44.1-1.8-1.61.8-1.91.91.9-1.81.9-1.62.0
Bone: marrow area3.27.07.8-2.5-2.62.8-2.82.72.7-2.72.7-2.52.5
Bone: maximum diameter0.30.50.7-0.8-0.60.8-0.80.80.7-0.70.7-0.60.6
Bone: maximum force1.32.32.9-1.4-1.61.7-1.71.61.5-1.51.6-1.41.2
Bone: maximum moment0.91.52.1-1.0-1.51.5-1.41.31.2-1.31.3-1.00.8
Mean time between licks in bursts0.50.61.20.81.1-0.90.8-0.8-0.70.9-0.70.8-0.3
Mean num. licks in bursts0.20.20.60.20.3-0.40.5-0.5-0.50.4-0.50.4-0.8
Cd content in liver1.11.21.4-1.2-1.11.2-1.11.11.0-1.21.2-1.10.6
Co content in liver2.22.62.9-1.1-1.61.7-1.71.71.7-1.61.7-1.51.6
Cu content in liver3.54.25.02.02.1-2.02.1-2.1-2.12.2-2.01.8-2.1
Fe content in liver4.35.15.9-2.4-2.12.4-2.32.32.3-2.22.4-2.22.0
K content in liver1.41.41.91.31.4-1.11.1-1.1-1.11.4-1.01.2-1.0
Mg content in liver3.43.45.92.41.8-1.71.7-1.7-1.81.8-1.72.0-1.7
Mn content in liver0.20.20.60.60.5-0.30.3-0.3-0.30.6-0.30.8-0.3
Na content in liver0.10.10.4-0.10.6-0.20.2-0.00.00.20.0-0.40.3
Rb content in liver0.10.10.2-0.1-0.50.4-0.30.30.2-0.50.3-0.1-0.1
Se content in liver3.23.96.62.62.1-1.91.9-1.9-1.92.0-1.81.8-1.8
Sr content in liver0.10.10.30.20.1-0.10.2-0.2-0.30.1-0.2-0.0-0.5
Zn content in liver0.40.51.2-0.2-1.10.8-0.80.60.5-0.90.5-0.60.2
Bone: minimum diameter1.01.82.2-1.2-1.31.5-1.51.41.4-1.31.3-1.21.2
Time in familiar zone, hab. session 10.00.00.10.3-0.2-0.10.1-0.1-0.20.0-0.10.4-0.3
Time in novel zone, hab. session 10.20.20.3-0.1-0.30.5-0.50.50.5-0.50.6-0.40.6
Total zone transitions, hab. session 12.73.85.72.41.8-1.91.9-1.9-1.91.9-1.82.4-1.6
Total locomotion distance, hab. session 11.92.84.32.11.5-1.71.7-1.6-1.61.6-1.61.9-1.3
Locomotion velocity, hab. session 11.92.63.92.01.5-1.61.6-1.6-1.61.6-1.51.8-1.3
Time in familiar zone, hab. session 20.90.91.60.41.1-1.31.1-1.0-0.91.2-1.20.6-0.4
Time in novel zone, hab. session 21.11.11.9-0.5-1.11.4-1.21.11.0-1.21.3-0.80.3
Total zone transitions, hab. session 20.30.40.60.60.7-0.70.6-0.6-0.50.8-0.70.7-0.0
Total locomotion distance, hab. session 22.12.73.61.51.8-1.91.7-1.6-1.51.9-1.81.7-0.8
Locomotion velocity, hab. session 22.53.44.31.71.9-2.11.9-1.8-1.72.1-2.01.9-1.0
Novel to familiar place preference ratio0.20.20.4-0.2-0.50.6-0.50.40.4-0.60.5-0.00.1
Novelty place preference0.20.20.4-0.2-0.50.5-0.40.40.4-0.60.5-0.00.1
Time in novel zone, NPP test0.20.20.4-0.3-0.50.6-0.50.50.4-0.70.6-0.10.2
Total zone transitions, NPP test1.72.53.21.61.5-1.61.5-1.6-1.51.6-1.61.8-1.4
Total locomotion distance, NPP test1.41.92.01.21.3-1.41.4-1.4-1.41.4-1.41.4-1.4
Locomotion velocity, NPP test2.02.83.21.51.6-1.81.7-1.7-1.71.7-1.81.7-1.5
Intraocular pressure1.21.72.1-1.1-1.51.4-1.41.31.3-1.21.3-1.21.2
Delta distance traveled before/after self-admin0.60.61.10.31.0-0.70.8-0.8-0.80.8-0.60.6-1.0
Delta ambulatory time before/after self-admin0.70.71.30.61.1-0.80.9-0.9-0.90.8-0.60.6-1.0
Parametrial fat weight2.54.87.4-1.8-2.12.0-2.12.22.3-2.22.0-2.22.7
Pavlov. Cond. lever latency0.70.92.5-1.6-0.90.6-0.80.80.9-0.70.6-1.21.1
Pavlov. Cond. magazine entry latency0.81.02.01.40.7-0.80.8-0.9-1.00.9-0.91.4-1.1
Pavlov. Cond. change in total contacts0.40.40.60.4-0.60.8-0.70.60.6-0.70.8-0.20.4
Pavlov. Cond. index score0.50.61.81.30.5-0.40.5-0.6-0.70.5-0.51.1-1.0
Pavlov. Cond. latency score0.40.51.61.30.4-0.30.4-0.5-0.60.4-0.51.0-0.9
Pavlov. Cond. lever contacts0.60.71.71.30.7-0.50.7-0.7-0.80.6-0.51.1-1.2
Pavlov. Cond. magazine entry number1.31.62.4-1.6-1.21.1-1.11.21.2-1.21.2-1.41.3
Pavlov. Cond. intertrial magazine entries0.00.10.2-0.40.1-0.00.1-0.1-0.1-0.00.1-0.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.50.61.91.40.4-0.40.5-0.6-0.70.4-0.51.1-1.0
Pavlov. Cond. response bias1.51.82.81.71.2-1.11.2-1.3-1.31.2-1.11.6-1.6
Pavlov. Cond. lever latency1.92.63.3-1.5-1.31.6-1.61.71.7-1.51.8-1.31.8
Pavlov. Cond. magazine entry latency0.20.30.6-0.8-0.60.5-0.40.40.4-0.50.5-0.80.1
Pavlov. Cond. change in total contacts1.21.62.11.11.1-1.31.3-1.4-1.41.1-1.41.1-1.4
Pavlov. Cond. index score0.40.50.90.50.6-0.70.7-0.8-0.80.6-0.80.4-1.0
Pavlov. Cond. latency score0.20.30.50.40.4-0.50.5-0.6-0.60.4-0.60.3-0.7
Pavlov. Cond. lever contacts1.21.72.21.31.0-1.31.3-1.4-1.41.1-1.51.1-1.5
Pavlov. Cond. magazine entry number0.10.10.20.40.3-0.20.2-0.2-0.20.3-0.20.4-0.0
Pavlov. Cond. intertrial magazine entries0.50.71.51.01.2-0.80.8-0.7-0.70.9-0.70.8-0.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.50.30.3-0.50.5-0.6-0.60.4-0.60.2-0.7
Pavlov. Cond. response bias0.71.01.80.90.6-0.91.0-1.1-1.10.8-1.10.8-1.3
Time in closed arm before self-admin0.40.50.80.60.9-0.70.7-0.7-0.70.8-0.50.4-0.8
Time in closed arm after self-admin0.10.10.3-0.2-0.10.2-0.20.20.1-0.10.4-0.5-0.1
Time in open arm before self-admin0.20.20.30.50.3-0.40.5-0.4-0.40.3-0.40.6-0.4
Time in open arm after self-admin1.82.02.81.31.3-1.41.4-1.4-1.41.3-1.51.7-1.3
Bone: periosteal estimation1.93.94.5-1.8-2.02.1-2.12.02.0-2.02.0-1.71.8
Bone: periosteal perimeter0.71.21.7-1.0-1.01.1-1.21.21.2-1.11.0-0.81.3
Bone: post-yield work0.10.20.4-0.5-0.40.6-0.50.40.4-0.30.5-0.3-0.1
Progressive ratio test 1 active lever presses0.00.00.2-0.1-0.0-0.10.2-0.2-0.30.0-0.10.0-0.5
Progressive ratio test 1 breakpoint0.10.10.3-0.10.0-0.20.2-0.3-0.30.1-0.20.1-0.6
Progressive ratio test 1 inactive lever presses1.01.01.3-1.1-1.11.0-1.01.01.0-1.11.0-1.10.9
Progressive ratio test 2 active lever presses0.00.00.1-0.0-0.10.0-0.00.00.0-0.00.2-0.1-0.0
Progressive ratio test 2 breakpoint0.00.00.00.1-0.0-0.10.1-0.1-0.10.10.20.0-0.1
Progressive ratio test 2 inactive lever presses0.10.10.20.20.4-0.40.4-0.3-0.40.4-0.10.2-0.4
Incentive Sensitization - Responses0.70.71.31.11.0-0.90.9-0.8-0.71.0-0.70.9-0.3
Incentive Sensitization - Breakpoint0.30.30.70.90.7-0.70.6-0.5-0.40.7-0.40.6-0.0
Sum of active levers in priming session hrs 5-60.50.51.60.60.5-0.60.8-0.8-0.90.6-0.60.5-1.2
Progressive ratio4.04.66.0-2.1-1.92.0-2.12.22.2-1.92.0-2.42.4
Food seeking constrained by brief footshock0.10.10.2-0.20.1-0.30.3-0.3-0.30.3-0.2-0.0-0.4
Seeking ratio, punishment vs. effort2.63.14.51.61.5-1.71.8-1.9-1.91.7-1.71.8-2.1
Retroperitoneal fat weight1.34.45.7-2.4-2.12.1-2.12.12.1-2.22.1-1.91.9
Reaction time number correct0.81.21.8-1.3-1.11.0-1.01.11.1-1.10.9-1.01.3
Reaction time mean minus median0.20.20.3-0.4-0.30.5-0.50.50.5-0.50.5-0.30.5
Reaction time mean minus median AUC0.10.10.2-0.2-0.40.5-0.40.40.3-0.50.3-0.20.1
Reaction time num false alarms0.10.10.20.40.2-0.40.3-0.2-0.10.3-0.30.10.4
Reaction time num false alarms AUC0.40.60.90.90.7-1.00.9-0.7-0.70.9-0.80.6-0.1
Reaction time trials correct on left0.81.21.8-1.3-1.11.0-1.01.11.1-1.10.9-1.01.3
Reaction time trials on left0.81.21.8-1.3-1.10.9-1.01.11.1-1.10.8-1.01.3
Reaction time mean0.10.20.3-0.2-0.50.6-0.50.40.4-0.50.4-0.10.1
Reaction time mean AUC0.40.50.8-0.6-0.80.9-0.80.80.7-0.80.7-0.40.4
Median of all reaction times0.10.20.4-0.2-0.60.6-0.50.50.4-0.50.4-0.10.3
Reaction time omissions0.10.10.5-0.2-0.00.1-0.20.30.3-0.10.2-0.00.7
Reaction time false alarm rate1.31.82.51.61.4-1.41.4-1.3-1.31.4-1.31.2-1.0
Reaction time premature initiation rate0.20.20.70.70.2-0.50.5-0.4-0.40.4-0.40.8-0.2
Reaction time premature initiations0.10.10.4-0.2-0.50.2-0.30.30.4-0.30.30.10.7
Std. dev. reaction times0.00.00.0-0.2-0.10.2-0.20.20.1-0.20.2-0.1-0.0
Reaction time trials completed0.81.21.8-1.3-1.10.9-1.01.11.1-1.10.8-1.01.3
Reaction time trials AUC0.81.11.8-1.3-1.00.9-1.01.11.1-1.00.8-1.01.3
Run reversals in cocaine runway, females0.10.10.4-0.2-0.60.5-0.40.20.2-0.60.2-0.3-0.3
Run reversals in cocaine runway, males0.20.20.4-0.0-0.10.5-0.40.50.5-0.60.5-0.40.4
Latency to leave start box in cocaine runway0.70.81.31.01.2-0.80.8-0.8-0.81.0-0.80.6-0.9
Latency to leave start box in cocaine runway, F0.60.71.00.71.0-0.80.7-0.8-0.81.0-0.90.5-0.8
Latency to leave start box in cocaine runway, M0.10.10.40.60.3-0.10.1-0.1-0.10.10.10.20.1
Std. dev. time between licks in bursts0.10.10.40.0-0.30.3-0.40.30.4-0.30.2-0.00.6
Total sessions with >9 infusions0.00.00.10.0-0.20.1-0.1-0.0-0.1-0.20.10.1-0.3
Short access day 1 total inactive lever presses0.10.10.4-0.00.4-0.20.3-0.3-0.30.3-0.2-0.1-0.6
Short access day 10 total inactive lever presses0.20.21.4-0.2-0.20.0-0.20.30.5-0.30.1-0.21.2
Short access day 1 total infusions1.11.22.11.01.0-1.01.1-1.1-1.20.9-1.01.1-1.5
Short access day 10 total infusions0.00.00.1-0.3-0.0-0.10.1-0.1-0.10.00.1-0.1-0.1
Short access total infusions0.00.00.30.0-0.10.10.0-0.1-0.2-0.10.1-0.0-0.6
Short access day 1 locomotion0.10.10.10.30.1-0.30.3-0.3-0.20.1-0.30.3-0.1
Short access day 10 total locomotion0.30.30.60.20.7-0.80.7-0.6-0.50.6-0.70.5-0.1
Short access total locomotion0.00.00.2-0.4-0.1-0.0-0.00.10.1-0.10.1-0.20.3
One hour access (0.3 mA shock)0.70.81.10.60.9-0.91.0-1.0-1.01.0-0.90.8-1.0
Compulsive drug intake3.03.13.81.11.9-1.81.8-1.8-1.81.8-1.91.5-2.0
One hour access (shock baseline)0.30.30.6-0.5-0.60.6-0.60.50.5-0.60.8-0.60.3
Social response proportion0.00.00.0-0.2-0.1-0.0-0.0-0.0-0.1-0.1-0.10.0-0.1
Social responses0.10.10.20.20.1-0.40.2-0.2-0.20.2-0.50.20.2
Social time0.10.20.60.80.3-0.50.4-0.3-0.30.3-0.50.50.2
Soleus weight0.20.70.7-0.8-0.90.8-0.80.80.8-0.80.8-0.80.7
Bone: stiffness1.11.72.1-1.1-1.41.5-1.51.41.4-1.31.3-0.91.2
Tibialis anterior weight0.82.83.21.81.5-1.81.7-1.7-1.71.6-1.71.7-1.5
Time to tail flick, vehicle, before self-admin2.72.86.1-0.8-1.61.5-1.71.81.9-1.61.6-1.42.5
Time to tail flick, vehicle, after self-admin0.10.10.20.30.3-0.40.4-0.4-0.40.4-0.40.2-0.3
Time to tail flick, test, before self-admin0.10.10.40.00.1-0.30.1-0.00.10.3-0.2-0.20.6
Time to tail flick, test, after self-admin0.00.00.10.2-0.10.1-0.10.10.1-0.10.2-0.30.2
Delta time to tail flick, vehicle, before/after SA1.81.84.10.81.2-1.11.2-1.4-1.51.3-1.31.1-2.0
Delta time to tail flick, test, before/after SA1.21.01.6-0.6-1.21.2-1.11.11.0-1.31.1-0.70.6
Tibia length2.87.98.8-2.9-2.52.9-2.82.92.9-2.63.0-2.92.7
Ambulatory time before self-admin0.70.82.0-1.1-0.80.6-0.70.80.9-0.60.7-0.81.4
Ambulatory time after self-admin0.10.10.3-0.30.4-0.40.3-0.1-0.00.2-0.1-0.00.5
Bone: tissue strength0.00.00.1-0.2-0.1-0.00.0-0.1-0.1-0.0-0.1-0.2-0.3
Total heroin consumption0.30.30.50.40.6-0.70.7-0.6-0.60.6-0.40.5-0.4
Bone: trabecular number1.11.72.21.31.4-1.21.3-1.3-1.31.3-1.21.5-1.4
Bone: trabecular spacing2.12.73.5-1.9-1.71.6-1.61.61.6-1.61.5-1.71.6
Bone: trabecular thickness0.30.40.6-0.5-0.80.7-0.60.60.5-0.70.7-0.60.2
Bone: trabecular tissue density0.10.10.5-0.7-0.20.3-0.20.30.2-0.20.3-0.70.0
Water consumed over 24 hours1.41.71.91.21.4-1.31.3-1.3-1.31.3-1.30.9-1.3
Number of responses in last shaping day1.51.64.21.11.1-1.01.2-1.3-1.41.0-1.01.1-2.0