Hub : Genes

Stat2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Stat2 0.35 0.13 0.0e+00 0.32 0.31 0.31 0.32 3.1e-30 1.0e-29 1.0e-29 3.6e-30
2 BLA mRNA stability Stat2 0.21 0.12 6.1e-12 0.22 0.21 0.2 0.21 9.5e-12 2.8e-11 5.5e-11 1.6e-11
3 Brain gene expression Stat2 0.54 0.17 0.0e+00 0.36 0.38 0.37 0.38 6.7e-35 1.2e-36 2.2e-36 1.1e-36
4 BLA gene expression Stat2 0.6 0.15 0.0e+00 0.62 0.62 0.63 0.63 2.8e-41 4.0e-42 2.8e-42 2.5e-42
5 IL mRNA stability Stat2 0.35 0.18 5.8e-05 0.06 0.06 0.01 0.07 1.6e-02 1.7e-02 2.2e-01 1.0e-02
6 OFC mRNA stability Stat2 0.3 0.15 5.3e-06 0.17 0.19 0.2 0.2 6.7e-05 2.6e-05 1.7e-05 1.6e-05
7 Liver mRNA stability Stat2 0.15 0.08 5.6e-17 0.13 0.14 0.13 0.14 2.2e-14 2.8e-15 1.2e-14 4.4e-15
8 Liver intron excision ratio chr7_700778_701250 0.5 0.15 0.0e+00 0.38 0.42 0.42 0.42 4.8e-45 1.1e-50 8.5e-51 6.1e-51
9 OFC gene expression Stat2 0.64 0.16 2.3e-14 0.39 0.41 0.43 0.43 2.4e-10 7.9e-11 1.5e-11 1.6e-11
10 Liver intron excision ratio chr7_700778_701021 0.55 0.14 0.0e+00 0.44 0.49 0.48 0.48 7.0e-53 3.9e-61 7.2e-61 6.0e-61
11 PL gene expression Stat2 0.66 0.17 0.0e+00 0.55 0.56 0.56 0.55 5.3e-73 3.1e-73 2.3e-74 9.0e-73
12 NAcc gene expression Stat2 0.88 0.01 0.0e+00 0.27 0.28 0.28 0.28 1.8e-31 6.5e-33 1.5e-32 3.0e-32
13 IL gene expression Stat2 0.57 0.19 3.2e-10 0.24 0.19 0.21 0.21 1.6e-06 2.2e-05 9.5e-06 9.1e-06
14 NAcc mRNA stability Stat2 0.09 0.06 3.8e-11 0.09 0.09 0.08 0.09 2.7e-10 1.4e-10 1.3e-09 3.0e-10
15 PL mRNA stability Stat2 0.23 0.11 0.0e+00 0.24 0.24 0.24 0.24 8.2e-26 8.3e-26 4.0e-26 1.6e-26
16 Adipose mRNA stability Stat2 0.09 0.07 3.1e-06 0.05 0.04 0.03 0.05 2.8e-06 3.7e-05 1.8e-04 4.3e-06
17 Adipose gene expression Stat2 0.28 0.14 0.0e+00 0.22 0.23 0.24 0.23 5.7e-24 4.1e-25 9.9e-27 1.2e-25
18 Liver intron excision ratio chr7_702686_705623 0.27 0.11 0.0e+00 0.25 0.24 0.24 0.25 1.0e-27 6.4e-27 1.4e-26 2.4e-27
19 Liver gene expression Stat2 0.26 0.12 0.0e+00 0.22 0.21 0.21 0.22 6.9e-24 2.1e-22 2.0e-22 1.1e-23
20 pVTA mRNA stability Stat2 0.1 0.07 4.7e-04 0.03 0.03 0 0.02 2.7e-02 2.7e-02 3.3e-01 4.4e-02
21 LHb gene expression Stat2 0.35 0.17 2.3e-06 0.24 0.22 0.25 0.23 2.0e-06 5.2e-06 1.2e-06 3.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.30.51.1-1.0-0.90.30.70.30.5-0.60.1-0.5-0.2-0.60.6-0.91.11.0-0.80.9-0.80.8-0.90.9
Area under the delay curve0.00.00.1-0.1-0.10.00.10.10.1-0.00.10.0-0.1-0.10.0-0.10.1-0.0-0.20.2-0.20.30.20.2
BMI with tail8.126.330.85.15.3-5.3-5.2-5.2-5.65.25.45.3-5.35.1-4.84.9-4.9-4.9-5.2-4.9-5.15.34.74.7
BMI without tail1.63.23.81.61.7-1.9-1.9-1.8-1.71.91.81.8-1.81.9-1.91.9-1.9-1.9-1.7-1.9-1.61.31.91.5
Body weight1.25.26.31.92.1-2.3-2.3-2.3-2.22.42.42.4-2.52.3-2.42.2-2.3-2.4-2.3-2.2-2.22.02.52.0
Weight adjusted by age0.10.10.20.40.3-0.2-0.2-0.1-0.00.20.10.20.00.2-0.20.3-0.3-0.40.2-0.30.1-0.10.5-0.2
Bone surface1.01.74.0-1.7-1.60.91.40.91.1-1.3-0.1-1.10.1-1.21.5-1.81.91.9-0.91.6-0.80.6-2.00.7
Bone volume0.81.43.1-1.6-1.50.71.10.61.0-1.10.1-0.9-0.2-1.01.2-1.61.71.7-1.11.4-1.10.8-1.71.1
Breakpoint value in progressive ratio session1.92.13.0-1.4-1.61.51.41.51.4-1.4-1.6-1.41.6-1.41.3-1.31.31.21.71.21.7-1.5-1.1-1.5
Number of licking bursts4.04.76.72.62.4-2.1-2.2-2.1-2.42.32.02.2-2.02.2-2.22.3-2.3-2.3-1.7-2.3-1.71.72.41.5
Context. condit. distance diff. score0.20.20.30.50.3-0.5-0.5-0.6-0.40.50.50.5-0.50.6-0.60.6-0.5-0.5-0.5-0.6-0.50.30.40.2
Locomotion velocity, session 10.20.20.8-0.7-0.60.10.20.10.6-0.10.1-0.1-0.3-0.1-0.0-0.40.40.3-0.50.3-0.60.3-0.20.9
Locomotion distance, session 10.40.61.2-1.0-1.00.70.90.70.6-0.8-0.4-0.70.3-0.80.8-1.01.11.0-0.10.9-0.10.0-1.00.4
Locomotion velocity, session 21.92.24.3-2.1-2.01.41.61.31.8-1.6-1.1-1.41.0-1.51.5-1.71.81.80.51.70.5-0.7-1.9-0.2
Locomotion distance, session 23.34.66.4-2.4-2.32.32.42.22.1-2.3-1.9-2.21.8-2.32.3-2.52.52.41.42.41.4-1.4-2.2-0.9
Locomotion velocity, session 35.16.07.1-2.5-2.52.62.52.62.7-2.4-2.6-2.52.6-2.42.3-2.32.32.32.52.32.5-2.6-2.3-2.2
Locomotion distance, session 30.10.10.3-0.3-0.30.40.40.40.2-0.2-0.3-0.30.3-0.20.2-0.20.20.20.40.20.3-0.6-0.2-0.2
Stereotopy head waving bouts, day 36.07.18.4-2.5-2.52.72.72.72.7-2.8-2.7-2.82.7-2.82.9-2.72.72.82.52.72.5-2.3-2.8-2.3
Stereotopy head waving duration, day 33.74.56.1-2.1-2.02.12.12.12.2-2.2-2.1-2.22.2-2.12.3-2.12.22.31.92.12.0-1.7-2.5-1.8
Locomotion velocity, session 70.10.10.4-0.4-0.30.30.40.30.1-0.4-0.2-0.30.2-0.40.4-0.40.50.50.10.50.0-0.1-0.60.0
Locomotion distance, session 70.20.20.60.60.5-0.4-0.5-0.4-0.80.50.20.5-0.20.4-0.40.6-0.6-0.5-0.1-0.6-0.00.20.40.1
Stereotopy head waving bouts, day 71.31.42.2-1.5-1.31.21.31.21.3-1.2-1.0-1.30.9-1.31.3-1.41.41.40.71.40.6-1.0-1.3-0.7
Stereotopy head waving duration, day 71.21.42.3-1.5-1.51.21.31.21.5-1.2-0.9-1.30.8-1.31.2-1.41.41.40.61.40.5-0.9-1.2-0.5
Locomotion velocity, session 82.02.44.5-2.1-2.11.61.81.61.8-1.7-1.3-1.51.1-1.61.5-1.81.91.70.81.90.7-0.9-1.5-0.5
Locomotion distance, session 80.40.61.0-0.9-1.00.91.00.80.8-0.9-0.7-0.80.7-0.80.8-0.90.90.80.60.90.6-0.6-0.7-0.4
Degree of sensitization distance0.60.61.00.80.7-0.8-0.8-0.8-1.00.80.80.8-0.80.8-0.70.7-0.7-0.7-0.8-0.7-0.81.00.70.7
Degree of sensitization stereotypy0.00.00.2-0.4-0.2-0.00.0-0.00.1-0.00.2-0.1-0.3-0.0-0.0-0.20.20.1-0.40.2-0.40.0-0.00.4
Conditioned locomotion1.31.52.51.41.4-1.2-1.4-1.2-1.41.40.91.3-1.01.3-1.41.5-1.6-1.5-0.5-1.4-0.50.71.60.4
Cocaine response after cond. corrected2.83.24.32.01.9-2.0-2.1-1.9-1.71.91.61.8-1.51.9-1.92.0-2.0-2.0-1.2-2.0-1.21.01.91.0
Cocaine response after cond. not corrected3.03.34.62.12.0-2.0-2.2-1.9-1.82.01.61.8-1.51.9-2.02.1-2.1-2.1-1.2-2.0-1.21.02.01.0
Cocaine response before conditioning0.60.71.0-0.9-0.90.90.90.90.8-0.9-0.8-0.90.7-0.90.9-1.00.90.90.70.90.7-0.7-0.8-0.6
Saline control response0.40.50.80.40.4-0.7-0.8-0.7-0.60.80.60.7-0.70.8-0.90.7-0.8-0.8-0.6-0.8-0.60.40.90.5
Bone: connectivity density0.20.30.7-0.8-0.70.30.60.30.5-0.50.0-0.4-0.1-0.50.5-0.70.80.8-0.60.6-0.50.6-0.80.7
Bone: cortical apparent density1.62.13.11.21.2-1.6-1.5-1.6-1.01.41.51.5-1.41.5-1.51.4-1.3-1.4-1.5-1.5-1.41.81.21.6
Bone: cortical area0.71.13.20.60.5-1.0-0.8-1.0-1.00.81.31.0-1.30.8-0.60.5-0.4-0.4-1.8-0.6-1.71.80.21.6
Bone: cortical porosity0.10.10.3-0.4-0.20.20.30.2-0.2-0.30.0-0.10.0-0.20.3-0.20.40.4-0.20.3-0.30.3-0.60.3
Bone: cortical porosity0.20.20.7-0.1-0.0-0.10.0-0.2-0.40.00.50.3-0.40.2-0.00.10.20.2-0.8-0.0-0.80.8-0.30.8
Bone: cortical thickness1.42.34.61.31.3-1.5-1.4-1.5-1.61.41.71.6-1.71.4-1.31.2-1.1-1.1-1.9-1.3-1.82.10.92.0
Bone: cortical thickness1.01.21.61.11.2-0.9-1.0-1.0-1.21.11.01.2-1.01.2-1.21.3-1.2-1.1-0.9-1.2-0.81.21.01.1
Bone: cortical tissue density1.11.52.31.01.0-1.4-1.2-1.4-0.81.21.21.3-1.21.3-1.31.2-1.1-1.2-1.3-1.3-1.21.51.11.4
Condit. Reinf. active minus inactive responses2.02.32.8-1.5-1.51.61.71.61.4-1.6-1.4-1.51.6-1.51.6-1.41.51.61.41.51.3-1.3-1.7-1.4
Condit. Reinf. active-inactive response ratio0.20.20.6-0.5-0.40.50.40.40.2-0.4-0.5-0.40.6-0.30.4-0.20.30.30.60.30.6-0.5-0.4-0.8
Condit. Reinf. active responses3.23.95.2-2.0-2.02.12.22.01.9-2.1-1.7-2.01.9-2.02.2-2.12.22.21.52.11.5-1.6-2.3-1.4
Condit. Reinf. inactive responses1.82.23.1-1.4-1.51.61.71.51.5-1.6-1.2-1.51.3-1.61.7-1.71.81.71.01.61.0-1.1-1.7-0.7
Incentive salience index mean1.61.92.5-1.5-1.51.51.61.41.4-1.5-1.1-1.41.2-1.41.4-1.51.61.50.91.50.9-1.0-1.6-1.0
Condit. Reinf. lever presses0.70.91.7-1.2-1.30.91.10.91.2-1.0-0.5-0.90.4-1.00.9-1.21.31.10.01.20.0-0.2-1.00.0
Condit. Reinf. active minus inactive responses1.51.93.3-1.1-1.01.31.21.41.2-1.3-1.6-1.41.7-1.31.3-1.01.01.21.81.11.8-1.6-1.3-1.7
Condit. Reinf. active-inactive response ratio0.30.41.5-0.0-0.00.40.20.40.4-0.3-0.8-0.40.9-0.30.30.0-0.00.11.20.11.2-1.0-0.1-1.1
Condit. Reinf. active responses1.21.62.1-1.1-1.01.31.31.31.1-1.3-1.3-1.31.4-1.31.4-1.21.21.31.41.21.4-1.2-1.4-1.3
Condit. Reinf. inactive responses0.40.50.8-0.6-0.70.70.80.70.6-0.8-0.6-0.70.6-0.70.8-0.90.90.90.30.80.4-0.3-0.9-0.3
Condit. Reinf. lever presses2.33.14.8-1.5-1.41.91.71.91.6-1.7-2.0-1.82.1-1.71.7-1.51.41.52.21.52.2-2.0-1.4-2.0
Condit. Reinf. lever reinforcers received0.81.11.7-0.8-0.71.11.01.10.9-1.0-1.2-1.11.3-1.01.1-0.90.91.01.30.91.3-1.1-1.1-1.2
Conditioned reinforcement - actives0.10.10.50.2-0.00.00.10.00.1-0.20.1-0.2-0.0-0.10.3-0.30.40.4-0.40.2-0.30.4-0.70.3
Conditioned reinforcement - inactives1.71.92.71.51.5-1.5-1.5-1.5-1.21.51.31.3-1.21.6-1.41.7-1.5-1.5-1.1-1.6-1.00.81.30.8
Conditioned locomotion2.12.64.6-1.2-1.01.71.61.61.3-1.7-1.5-1.71.7-1.72.0-1.61.71.81.51.61.5-1.2-2.1-1.4
Patch foraging indifference point 0 sec4.06.48.72.42.5-2.5-2.4-2.6-2.82.42.72.6-2.72.5-2.42.4-2.2-2.2-2.8-2.3-2.83.02.12.8
Patch foraging indifference point AUC0.60.71.1-0.7-0.70.80.80.80.7-0.8-0.8-0.90.9-0.90.9-0.90.70.70.90.70.8-1.1-0.6-0.9
Delay disc. indifference point, 0s delay0.80.93.20.50.6-0.8-0.6-0.7-0.80.61.10.9-1.30.6-0.70.4-0.3-0.5-1.6-0.3-1.61.70.61.8
Delay disc. indifference point, 16s delay0.30.30.5-0.5-0.60.50.60.70.5-0.5-0.5-0.60.5-0.60.6-0.60.50.60.50.70.5-0.4-0.5-0.3
Delay disc. indifference point, 2s delay0.10.10.60.00.2-0.3-0.1-0.2-0.40.20.40.3-0.50.2-0.20.1-0.0-0.2-0.6-0.3-0.60.80.40.3
Delay disc. indifference point, 24s delay0.20.20.60.50.5-0.4-0.4-0.3-0.60.40.40.5-0.50.3-0.40.3-0.4-0.5-0.4-0.2-0.40.50.80.5
Delay disc. indifference point, 4s delay0.50.61.0-1.0-0.70.70.90.80.7-0.9-0.6-0.80.5-0.90.8-1.01.00.90.30.90.3-0.2-0.8-0.3
Delay disc. indifference point, 8s delay0.10.10.60.50.4-0.4-0.3-0.2-0.20.40.20.4-0.20.3-0.50.5-0.5-0.6-0.0-0.3-0.00.20.80.2
Indifference point function ln k0.20.30.40.40.4-0.5-0.5-0.5-0.50.50.50.5-0.50.6-0.50.6-0.5-0.4-0.6-0.5-0.60.70.20.6
Indifference point function log k0.20.30.40.40.4-0.5-0.5-0.5-0.50.50.50.5-0.50.6-0.50.6-0.5-0.4-0.6-0.5-0.60.70.20.6
Patch foraging total patch changes 0 sec3.86.28.12.52.6-2.5-2.4-2.5-2.82.42.72.6-2.62.4-2.32.3-2.2-2.2-2.6-2.3-2.72.82.02.7
Patch foraging total patch changes 12 sec2.33.04.22.02.1-1.7-1.7-1.7-2.01.71.71.8-1.51.7-1.71.8-1.8-1.8-1.4-1.8-1.41.51.91.4
Patch foraging total patch changes 18 sec0.00.00.10.30.2-0.2-0.2-0.2-0.20.20.30.2-0.20.1-0.10.1-0.2-0.2-0.1-0.1-0.30.20.30.3
Patch foraging total patch changes 24 sec0.50.60.90.70.7-0.7-0.6-0.7-0.70.70.90.7-0.90.7-0.80.6-0.6-0.7-0.9-0.6-1.00.80.80.9
Patch foraging total patch changes 6 sec2.23.24.11.81.9-1.8-1.7-1.8-2.01.71.91.8-1.81.8-1.71.7-1.6-1.6-1.9-1.7-1.91.81.41.9
Patch foraging time to switch 0 sec0.10.20.50.00.0-0.4-0.3-0.4-0.20.40.30.4-0.60.4-0.40.3-0.2-0.3-0.7-0.2-0.60.50.50.6
Patch foraging water rate 0 sec0.71.21.61.21.2-1.1-1.1-1.1-1.01.11.01.1-0.81.2-1.21.2-1.2-1.2-0.7-1.3-0.80.91.00.8
Patch foraging water rate 12 sec1.11.72.71.61.6-1.3-1.4-1.3-1.31.41.21.3-1.11.4-1.31.5-1.5-1.4-0.8-1.5-0.91.01.30.6
Patch foraging water rate 18 sec0.30.40.90.60.7-0.3-0.5-0.3-0.20.6-0.10.40.10.6-0.71.0-0.9-0.80.5-0.80.7-0.60.8-0.7
Patch foraging water rate 24 sec2.23.15.22.22.2-1.6-1.9-1.6-1.81.91.31.8-1.11.9-1.92.2-2.3-2.2-0.5-2.1-0.50.82.20.5
Patch foraging water rate 6 sec0.20.31.2-0.2-0.30.40.20.40.4-0.3-0.7-0.40.8-0.20.20.0-0.00.10.90.11.0-1.1-0.4-1.1
Seeking ratio, delayed vs. immediate footshock1.41.62.7-1.4-1.31.31.31.21.3-1.4-1.1-1.31.2-1.31.4-1.41.51.50.91.40.9-0.9-1.6-0.7
Distance traveled before self-admin0.91.01.5-0.8-0.81.21.21.10.7-1.1-1.0-0.91.1-1.11.2-1.11.11.11.01.01.1-0.5-1.0-1.0
Distance traveled after self-admin0.20.20.3-0.3-0.20.50.50.50.3-0.5-0.3-0.40.4-0.50.5-0.60.50.60.30.30.40.2-0.5-0.1
Extensor digitorum longus weight6.023.528.34.44.4-5.0-5.1-5.1-4.55.14.75.0-4.85.1-5.35.1-5.1-5.2-4.3-5.0-4.44.15.34.3
Bone: elastic displacement0.00.00.1-0.10.2-0.10.0-0.0-0.1-0.10.0-0.10.0-0.10.2-0.10.10.2-0.10.1-0.00.1-0.30.2
Bone: elastic work0.50.71.60.60.8-0.9-0.7-0.8-1.10.70.90.9-1.00.7-0.70.6-0.5-0.5-1.1-0.6-1.01.30.51.2
Bone: endosteal estimation0.51.12.61.00.9-1.2-1.0-1.2-1.10.91.40.9-1.31.0-0.70.7-0.7-0.7-1.6-0.8-1.61.10.40.9
Bone: endosteal perimeter0.30.61.8-0.6-0.70.70.80.70.4-0.9-0.2-0.60.5-0.81.1-0.91.11.10.10.9-0.10.1-1.3-0.2
Epididymis fat weight0.10.20.5-0.40.10.40.30.4-0.1-0.3-0.5-0.30.5-0.40.4-0.30.20.20.60.30.6-0.6-0.1-0.7
Delta time in closed arm before/after self-admin1.81.73.71.81.9-1.2-1.4-1.2-1.41.40.91.2-0.71.4-1.31.7-1.7-1.7-0.3-1.7-0.30.21.60.3
Delta time in open arm before/after self-admin0.90.91.40.60.6-0.9-0.8-0.9-0.81.01.01.0-1.21.0-1.20.8-0.9-0.9-1.2-0.7-1.10.91.10.9
Diff in mean of infusions in LGA sessions2.02.22.9-1.4-1.31.51.51.51.3-1.5-1.5-1.51.6-1.51.5-1.41.41.41.61.41.6-1.7-1.4-1.5
Delay discount exponential model param0.00.00.00.10.2-0.1-0.2-0.2-0.10.10.00.00.00.2-0.10.2-0.1-0.00.1-0.20.1-0.2-0.2-0.1
Extinction: sum of active levers before priming2.72.75.1-1.3-1.41.71.51.71.5-1.4-1.9-1.61.9-1.51.4-1.21.11.12.21.32.2-2.3-1.0-2.3
Active lever presses in extinction session 61.41.41.7-1.2-1.11.31.31.31.0-1.2-1.1-1.11.2-1.21.2-1.21.21.21.11.31.2-0.9-1.1-1.0
Bone: final force2.33.76.51.51.6-1.9-1.7-1.9-2.11.82.21.9-2.31.8-1.71.5-1.4-1.4-2.5-1.6-2.52.41.42.3
Bone: final moment2.13.56.31.51.6-1.8-1.7-1.8-2.01.72.21.9-2.31.7-1.61.5-1.4-1.4-2.5-1.5-2.42.41.32.2
Food consumed during 24 hour testing period0.50.61.10.90.9-0.7-0.7-0.7-1.10.70.80.8-0.80.7-0.60.7-0.7-0.7-0.7-0.7-0.70.90.70.8
Glucose2.03.03.61.71.7-1.7-1.7-1.7-1.71.71.81.7-1.81.8-1.81.7-1.7-1.7-1.7-1.7-1.81.61.81.9
Heart weight0.00.10.10.1-0.1-0.4-0.4-0.3-0.10.30.30.1-0.10.3-0.20.3-0.3-0.3-0.1-0.4-0.2-0.20.1-0.1
Delay discount hyperbolic model param0.00.00.2-0.0-0.00.1-0.00.00.1-0.1-0.2-0.10.20.00.10.00.00.10.3-0.00.3-0.4-0.3-0.3
Intermittent access intake day 1-15 change0.10.10.2-0.00.30.30.30.30.3-0.3-0.3-0.40.5-0.20.4-0.20.30.30.40.30.4-0.3-0.4-0.5
Intermittent access intake escalation0.10.10.60.60.8-0.0-0.1-0.0-0.00.1-0.2-0.00.30.2-0.00.4-0.3-0.30.6-0.20.5-0.50.3-0.6
Intermittent access intake escalation 20.30.31.0-0.10.00.40.30.50.5-0.4-0.7-0.50.8-0.40.5-0.10.20.21.00.31.0-0.9-0.2-0.9
Intermitt. access day 1 inactive lever presses0.10.10.80.40.3-0.2-0.3-0.2-0.20.2-0.10.00.20.3-0.20.5-0.4-0.40.5-0.40.5-0.90.1-0.3
Intermitt. access day 15 inactive lever presses0.50.51.3-0.0-0.40.80.60.70.8-0.6-0.9-0.71.0-0.60.6-0.40.40.41.10.51.2-1.1-0.5-0.9
Intermitt. access escalation Index0.40.31.4-1.1-1.20.30.50.30.5-0.5-0.1-0.40.0-0.40.4-0.60.70.7-0.40.5-0.4-0.0-0.90.5
Intermittent access day 1 total infusions0.30.40.80.60.5-0.6-0.5-0.6-0.50.60.80.7-0.70.6-0.60.5-0.5-0.4-0.8-0.5-0.80.70.30.9
Intermittent access day 15 total infusions0.30.31.00.91.0-0.5-0.5-0.6-0.50.50.60.6-0.40.6-0.50.6-0.5-0.6-0.4-0.6-0.40.50.40.5
Intermittent access terminal intake (last 3 days)0.20.30.70.50.5-0.5-0.4-0.5-0.30.40.70.4-0.50.4-0.40.3-0.2-0.2-0.7-0.4-0.80.80.10.8
Intermittent access total infusions0.50.61.11.00.9-0.8-0.7-0.8-0.70.70.90.8-0.70.8-0.80.7-0.7-0.7-0.8-0.7-0.80.90.60.8
Intermittent access day 1 locomotion0.00.00.10.10.0-0.1-0.1-0.10.10.10.00.0-0.00.1-0.20.1-0.1-0.10.0-0.10.0-0.20.1-0.1
Intermittent access day 15 total locomotion0.20.30.7-0.1-0.10.40.40.40.8-0.5-0.5-0.60.6-0.40.5-0.30.40.50.60.40.5-0.9-0.7-0.5
Intermittent access total locomotion0.20.20.6-0.3-0.20.50.50.50.8-0.5-0.5-0.50.5-0.50.5-0.50.50.50.40.50.4-0.6-0.5-0.4
Intermittent access standard deviation0.10.10.20.30.50.10.20.10.2-0.1-0.2-0.20.3-0.10.30.00.10.10.30.10.3-0.3-0.3-0.5
Left kidney weight0.10.20.7-0.8-0.6-0.2-0.0-0.20.2-0.10.4-0.1-0.5-0.00.0-0.20.40.3-0.80.2-0.90.1-0.50.7
Right kidney weight0.30.92.3-1.5-1.20.80.90.81.2-0.9-0.7-1.00.7-0.90.9-0.91.11.10.41.00.4-1.0-1.5-0.6
Cocaine induced anxiety1.92.23.1-1.5-1.61.61.61.61.6-1.6-1.3-1.51.3-1.61.6-1.81.81.71.11.71.1-0.8-1.6-0.9
Post-drug Anxiety0.70.81.7-1.1-1.20.91.10.80.9-1.0-0.5-0.80.5-1.01.0-1.21.31.20.11.20.10.1-1.00.0
Baseline Anxiety0.00.00.10.10.0-0.2-0.1-0.2-0.20.20.00.1-0.10.2-0.20.2-0.3-0.3-0.0-0.2-0.0-0.20.3-0.0
Tail length4.814.521.3-3.8-3.93.93.73.94.1-3.6-4.1-4.04.0-3.63.4-3.43.33.34.13.54.2-4.6-3.2-4.0
Length with tail1.97.09.0-3.0-3.02.72.72.73.0-2.6-2.7-2.72.6-2.62.4-2.52.52.42.52.62.6-3.0-2.1-2.5
Length without tail0.10.10.50.00.1-0.3-0.2-0.3-0.20.10.50.3-0.50.1-0.1-0.00.1-0.0-0.70.0-0.70.70.10.6
Times rat made contact with spout1.31.52.01.21.3-1.2-1.3-1.2-1.41.31.11.3-1.11.3-1.31.3-1.3-1.3-0.9-1.3-0.91.01.40.9
Lifetime Intake1.21.32.21.21.2-1.1-1.0-1.2-1.01.01.41.1-1.21.1-1.10.9-0.9-0.9-1.4-1.0-1.41.50.81.3
Liver weight, left1.82.94.21.82.0-1.7-1.8-1.7-2.01.81.71.8-1.61.8-1.71.9-1.8-1.7-1.5-1.8-1.51.51.51.2
Liver weight, right0.81.41.90.80.9-1.3-1.3-1.3-0.91.31.31.1-1.41.3-1.21.2-1.1-1.2-1.3-1.2-1.30.91.01.0
Locomotor activity4.36.810.6-3.3-3.22.82.82.72.8-2.6-2.7-2.62.3-2.52.3-2.52.62.62.12.72.2-2.5-2.6-1.9
Locomotor testing distance1.62.64.3-2.1-1.91.71.71.71.6-1.6-1.6-1.61.5-1.61.5-1.51.61.71.31.71.3-1.5-1.7-1.1
Locomotor testing rearing0.00.00.1-0.2-0.20.1-0.00.10.00.1-0.2-0.00.00.0-0.20.2-0.2-0.10.3-0.00.2-0.40.2-0.2
Locomotion in novel chamber0.30.40.80.60.7-0.7-0.7-0.7-0.90.60.70.6-0.60.6-0.40.6-0.6-0.6-0.6-0.8-0.70.70.40.6
Locomotion in novel chamber post-restriction3.44.14.9-1.8-1.82.22.02.21.8-2.1-2.0-2.12.2-2.12.2-2.12.01.92.12.02.0-1.9-1.9-2.0
Fecal boli incidents, locomotor time 10.80.91.71.10.9-1.0-1.1-0.9-0.81.10.80.9-0.81.0-1.01.1-1.2-1.2-0.4-1.2-0.50.51.30.4
Change in fecal boli incidents, locomotor task0.80.81.6-1.0-0.90.91.00.80.8-1.0-0.6-0.80.6-0.91.0-1.11.21.20.31.30.4-0.2-1.2-0.2
Time >=10cm from walls, locomotor time 10.50.51.30.50.6-0.6-0.5-0.6-0.50.50.80.6-0.90.5-0.40.3-0.3-0.3-1.1-0.3-1.11.10.31.1
Bouts of movement, locomotor time 10.40.50.8-0.8-0.70.60.60.80.6-0.7-0.7-0.70.8-0.70.7-0.60.60.60.70.70.7-0.9-0.7-0.6
Total resting periods, locomotor time 11.21.31.7-1.2-1.31.11.11.21.2-1.1-1.2-1.21.2-1.21.1-1.11.01.11.11.11.1-1.3-1.1-1.0
Rest time, locomotor task time 10.60.60.9-0.8-1.00.80.80.90.9-0.8-0.7-0.80.7-0.90.8-0.90.80.80.60.90.6-0.6-0.8-0.6
Distance moved, locomotor task time 10.50.61.60.60.5-0.7-0.5-0.8-0.80.60.90.7-0.90.7-0.50.4-0.3-0.4-1.1-0.5-1.11.30.31.3
Vertical activity count, locomotor time 11.41.52.01.31.4-1.2-1.2-1.3-1.31.21.21.3-1.21.3-1.21.3-1.2-1.2-1.2-1.2-1.11.21.01.2
Time >=10cm from walls, locomotor time 21.41.52.01.31.4-1.3-1.3-1.2-1.11.31.21.2-1.11.3-1.21.3-1.3-1.3-1.0-1.4-1.00.81.21.0
Bouts of movement, locomotor time 20.50.61.1-1.0-0.90.70.80.91.0-0.8-0.5-0.80.4-0.80.8-0.90.90.90.21.00.2-0.3-1.00.1
Total resting periods, locomotor time 20.50.61.1-1.0-1.00.70.80.81.0-0.8-0.4-0.70.4-0.80.8-0.91.00.90.11.00.1-0.2-1.00.2
Rest time, locomotor task time 20.20.20.6-0.7-0.80.40.40.40.3-0.4-0.2-0.40.1-0.40.4-0.50.60.5-0.00.6-0.10.0-0.4-0.0
Distance moved, locomotor task time 20.10.20.50.70.6-0.3-0.4-0.4-0.30.40.20.4-0.20.5-0.50.5-0.6-0.50.0-0.60.1-0.10.50.1
Vertical activity count, locomotor time 21.81.92.81.71.5-1.4-1.5-1.4-1.11.51.21.4-1.21.6-1.61.7-1.7-1.7-0.9-1.6-0.80.71.60.9
Light reinforcement 13.76.67.3-2.5-2.52.72.72.72.7-2.7-2.6-2.62.6-2.62.6-2.62.62.62.42.62.3-2.4-2.6-2.3
Light reinforcement 20.91.21.7-1.0-0.91.21.21.21.0-1.2-1.2-1.11.2-1.11.1-1.11.11.21.11.11.2-0.8-1.3-0.8
Bone: marrow area0.41.02.30.90.8-1.2-1.0-1.1-1.00.91.30.8-1.20.9-0.70.7-0.6-0.6-1.5-0.8-1.51.00.40.8
Bone: maximum diameter0.50.92.4-1.1-1.30.80.90.80.9-1.0-0.5-0.90.5-0.91.1-1.21.31.3-0.11.10.0-0.2-1.5-0.2
Bone: maximum force2.54.47.21.81.7-2.1-2.0-2.1-2.32.02.42.1-2.52.0-1.91.7-1.6-1.6-2.7-1.7-2.62.61.52.4
Bone: maximum moment2.44.27.11.71.7-2.1-1.9-2.1-2.21.92.32.1-2.41.9-1.81.7-1.6-1.6-2.7-1.7-2.52.61.52.4
Mean time between licks in bursts0.60.81.5-0.5-0.40.90.90.90.6-0.9-1.0-0.91.2-0.90.9-0.70.80.81.10.71.1-1.1-1.0-1.2
Mean num. licks in bursts0.91.12.1-1.4-1.21.01.11.01.1-1.1-1.1-1.11.0-1.11.0-1.11.11.10.91.20.9-0.8-1.1-0.7
Cd content in liver0.50.51.30.81.0-0.7-0.6-0.6-1.10.60.80.7-0.60.6-0.50.5-0.6-0.8-0.7-0.6-0.70.70.80.7
Co content in liver0.91.11.7-1.0-1.21.01.01.11.3-1.0-1.2-1.01.3-1.00.9-0.80.80.81.30.81.3-1.3-0.7-1.1
Cu content in liver1.01.24.40.70.6-1.1-0.8-1.0-1.10.81.31.1-1.20.9-0.70.7-0.5-0.5-1.6-0.7-1.61.80.42.1
Fe content in liver0.70.81.11.01.1-0.9-1.0-0.9-1.00.90.90.9-0.80.9-0.91.0-1.0-1.1-0.6-1.0-0.70.81.10.6
K content in liver0.70.71.3-1.1-1.10.80.90.90.6-0.9-0.7-0.90.6-1.01.1-1.11.01.00.31.00.4-0.4-0.9-0.5
Mg content in liver0.60.61.2-0.9-0.90.70.80.80.5-0.9-0.5-0.80.5-0.91.1-1.11.00.90.10.90.2-0.3-0.8-0.4
Mn content in liver1.01.12.6-1.2-1.10.91.11.00.7-1.2-0.4-1.00.4-1.21.5-1.51.61.5-0.11.4-0.10.0-1.40.1
Na content in liver0.10.10.5-0.2-0.2-0.0-0.1-0.0-0.20.10.20.2-0.3-0.0-0.0-0.10.1-0.1-0.30.1-0.40.70.30.3
Rb content in liver0.50.72.00.50.6-0.8-0.6-0.7-0.80.51.00.7-1.00.6-0.30.4-0.2-0.3-1.3-0.4-1.31.40.11.4
Se content in liver0.10.10.3-0.5-0.40.20.30.20.2-0.3-0.3-0.20.2-0.30.2-0.30.30.20.10.30.2-0.1-0.00.2
Sr content in liver0.10.10.60.00.20.2-0.00.10.20.0-0.3-0.20.40.0-0.10.2-0.2-0.00.8-0.20.5-0.8-0.2-0.8
Zn content in liver1.41.64.1-1.0-1.11.21.01.31.2-0.9-1.6-1.11.6-1.00.8-0.70.50.61.90.71.9-1.8-0.5-2.0
Bone: minimum diameter0.20.31.30.1-0.0-0.5-0.3-0.5-0.40.30.80.4-0.70.4-0.20.2-0.0-0.0-1.1-0.2-1.11.1-0.20.9
Time in familiar zone, hab. session 14.94.66.4-1.8-1.82.32.22.31.6-2.1-2.4-2.12.4-2.22.1-2.01.91.92.52.02.5-2.3-1.8-2.3
Time in novel zone, hab. session 13.02.95.51.31.2-1.8-1.6-1.8-1.41.62.01.7-2.11.6-1.51.4-1.2-1.3-2.3-1.4-2.32.21.22.2
Total zone transitions, hab. session 10.71.01.7-1.3-1.11.11.21.10.9-1.1-0.8-1.00.7-1.11.1-1.31.31.20.41.20.4-0.4-1.00.1
Total locomotion distance, hab. session 12.43.45.4-2.2-2.01.92.11.91.9-2.0-1.4-1.91.4-2.02.1-2.22.32.10.92.20.8-1.0-2.0-0.5
Locomotion velocity, hab. session 12.43.45.0-2.2-2.02.02.11.92.0-2.0-1.5-1.91.5-2.02.0-2.12.22.11.12.11.0-1.2-1.9-0.7
Time in familiar zone, hab. session 24.34.46.7-1.9-1.82.12.02.11.9-2.0-2.4-2.02.5-2.02.0-1.81.71.82.61.82.6-2.3-1.9-2.4
Time in novel zone, hab. session 24.84.77.51.91.8-2.2-2.0-2.2-2.02.02.52.2-2.62.1-2.01.8-1.7-1.8-2.7-1.9-2.72.71.92.7
Total zone transitions, hab. session 20.30.42.6-0.2-0.1-0.3-0.1-0.3-0.20.20.70.4-0.80.3-0.3-0.00.10.0-1.2-0.0-1.21.1-0.01.6
Total locomotion distance, hab. session 20.60.81.5-1.2-1.20.91.00.91.2-1.0-0.7-0.80.5-0.90.9-1.11.11.00.31.00.3-0.3-0.90.1
Locomotion velocity, hab. session 20.81.01.9-1.4-1.31.01.21.01.3-1.1-0.7-0.90.6-1.11.0-1.21.31.20.31.20.3-0.3-1.00.1
Novel to familiar place preference ratio2.22.34.91.11.1-1.3-1.1-1.3-1.31.31.91.5-1.91.4-1.31.1-1.0-1.1-2.1-1.1-2.22.11.22.1
Novelty place preference1.41.53.50.80.9-1.0-0.8-1.0-1.11.01.51.2-1.51.1-1.00.8-0.7-0.8-1.7-0.9-1.91.80.91.8
Time in novel zone, NPP test2.02.14.41.11.1-1.2-1.1-1.3-1.31.31.81.4-1.81.3-1.21.1-1.0-1.1-2.0-1.1-2.12.01.12.0
Total zone transitions, NPP test0.20.21.10.10.3-0.3-0.2-0.3-0.40.30.50.5-0.70.3-0.40.1-0.1-0.3-0.8-0.2-0.70.80.51.0
Total locomotion distance, NPP test0.10.10.5-0.4-0.30.10.30.10.3-0.20.1-0.0-0.2-0.20.2-0.40.40.2-0.50.3-0.50.5-0.00.7
Locomotion velocity, NPP test0.20.20.5-0.7-0.60.40.60.40.6-0.5-0.2-0.40.1-0.50.5-0.70.70.5-0.10.6-0.10.1-0.30.3
Intraocular pressure0.30.41.5-0.1-0.40.60.40.60.5-0.4-0.7-0.40.9-0.50.3-0.20.10.11.20.31.1-0.80.0-0.9
Delta distance traveled before/after self-admin0.00.00.20.00.0-0.2-0.2-0.20.00.10.20.1-0.20.2-0.20.1-0.1-0.1-0.3-0.4-0.20.20.00.5
Delta ambulatory time before/after self-admin0.00.10.4-0.10.0-0.1-0.1-0.1-0.00.00.20.1-0.30.1-0.1-0.00.10.1-0.4-0.2-0.40.4-0.10.6
Parametrial fat weight0.00.10.30.10.10.10.00.2-0.2-0.1-0.3-0.10.3-0.20.3-0.10.10.10.30.10.5-0.1-0.2-0.4
Pavlov. Cond. lever latency0.20.30.60.60.7-0.4-0.6-0.4-0.80.60.10.3-0.20.5-0.50.7-0.8-0.70.1-0.70.2-0.30.7-0.3
Pavlov. Cond. magazine entry latency1.51.92.7-1.2-1.31.41.41.41.5-1.4-1.4-1.31.6-1.41.4-1.31.31.31.51.31.4-1.3-1.4-1.6
Pavlov. Cond. change in total contacts0.20.20.50.40.4-0.4-0.2-0.4-0.30.30.70.5-0.40.4-0.30.4-0.3-0.3-0.6-0.4-0.70.70.10.4
Pavlov. Cond. index score0.60.81.3-1.0-1.10.91.00.91.1-1.0-0.6-0.80.8-0.90.9-1.01.11.00.51.00.4-0.3-1.0-0.5
Pavlov. Cond. latency score0.81.01.7-1.2-1.31.01.11.01.3-1.1-0.6-0.90.7-1.01.0-1.11.21.20.41.20.4-0.3-1.2-0.4
Pavlov. Cond. lever contacts0.20.30.6-0.7-0.80.40.60.40.7-0.50.1-0.30.0-0.50.4-0.70.80.6-0.30.7-0.40.4-0.50.5
Pavlov. Cond. magazine entry number0.60.71.10.80.9-0.8-0.9-0.8-1.00.90.70.8-0.90.8-0.80.8-0.8-0.8-0.8-0.8-0.70.70.81.0
Pavlov. Cond. intertrial magazine entries0.10.10.60.20.20.10.10.1-0.10.0-0.3-0.10.30.0-0.10.2-0.2-0.10.4-0.20.4-0.80.1-0.4
Pavlov. Cond. lever-magazine prob. diff.0.81.01.4-1.1-1.21.01.11.01.2-1.1-0.7-0.90.9-1.01.0-1.11.21.10.61.10.5-0.4-1.2-0.6
Pavlov. Cond. response bias0.81.01.3-1.1-1.11.01.11.01.0-1.1-0.9-0.91.0-1.01.0-1.01.01.00.91.00.8-0.7-0.9-1.0
Pavlov. Cond. lever latency1.72.32.61.61.5-1.6-1.6-1.6-1.51.51.61.6-1.61.5-1.41.5-1.4-1.4-1.5-1.5-1.61.61.21.3
Pavlov. Cond. magazine entry latency2.63.03.3-1.7-1.71.81.81.81.6-1.8-1.8-1.81.8-1.71.8-1.71.71.71.61.71.7-1.7-1.6-1.7
Pavlov. Cond. change in total contacts0.70.91.5-0.9-0.91.01.01.00.7-1.0-1.0-1.01.1-0.91.0-0.80.90.91.00.91.1-1.1-0.9-1.2
Pavlov. Cond. index score2.12.73.0-1.6-1.61.71.71.71.4-1.7-1.7-1.71.7-1.61.7-1.51.51.61.71.51.7-1.7-1.5-1.7
Pavlov. Cond. latency score2.42.93.3-1.7-1.71.81.81.81.5-1.8-1.8-1.81.8-1.71.7-1.71.71.71.71.71.7-1.7-1.6-1.7
Pavlov. Cond. lever contacts1.31.72.4-1.2-1.21.41.31.41.2-1.3-1.5-1.31.5-1.31.2-1.21.21.21.51.21.5-1.5-1.1-1.3
Pavlov. Cond. magazine entry number2.32.83.11.61.7-1.7-1.7-1.7-1.51.71.71.7-1.71.7-1.81.6-1.7-1.7-1.5-1.6-1.61.51.71.6
Pavlov. Cond. intertrial magazine entries0.91.22.10.80.8-1.1-1.2-1.1-0.61.31.01.1-1.11.2-1.41.3-1.3-1.4-0.9-1.2-0.90.71.40.8
Pavlov. Cond. lever-magazine prob. diff.2.22.83.1-1.7-1.71.81.71.81.5-1.7-1.7-1.71.8-1.71.7-1.61.61.71.61.61.7-1.7-1.7-1.6
Pavlov. Cond. response bias2.02.83.6-1.5-1.51.71.71.71.6-1.6-1.8-1.71.8-1.61.6-1.51.51.51.81.51.9-1.9-1.5-1.8
Time in closed arm before self-admin0.10.10.6-0.3-0.4-0.2-0.0-0.10.2-0.00.40.1-0.4-0.0-0.0-0.20.20.2-0.7-0.1-0.70.8-0.20.6
Time in closed arm after self-admin0.40.40.80.70.7-0.7-0.6-0.7-0.50.60.70.6-0.60.6-0.50.5-0.5-0.4-0.7-0.9-0.70.80.30.7
Time in open arm before self-admin0.10.10.40.30.40.30.20.3-0.1-0.3-0.3-0.30.5-0.20.6-0.10.20.30.60.40.6-0.3-0.6-0.5
Time in open arm after self-admin1.21.31.91.41.4-1.1-1.2-1.1-1.31.21.11.2-1.11.2-1.21.2-1.3-1.2-0.9-0.8-0.90.91.30.7
Bone: periosteal estimation0.81.64.50.80.7-1.3-1.0-1.3-1.20.91.71.1-1.61.0-0.80.7-0.5-0.5-2.1-0.8-2.11.80.31.6
Bone: periosteal perimeter0.10.20.8-0.2-0.30.10.30.1-0.1-0.30.4-0.0-0.3-0.20.5-0.40.60.7-0.80.4-0.80.9-0.90.7
Bone: post-yield work0.30.50.70.50.3-0.7-0.7-0.8-0.40.70.70.6-0.80.8-0.80.8-0.7-0.7-0.8-0.6-0.80.40.60.5
Progressive ratio test 1 active lever presses1.61.62.01.31.0-1.3-1.3-1.3-1.11.31.41.2-1.31.3-1.41.3-1.2-1.3-1.3-1.3-1.31.21.31.0
Progressive ratio test 1 breakpoint1.61.72.01.31.0-1.4-1.3-1.4-1.21.31.41.3-1.41.4-1.41.3-1.2-1.3-1.4-1.3-1.41.31.21.0
Progressive ratio test 1 inactive lever presses0.00.00.30.1-0.3-0.2-0.1-0.20.10.00.30.0-0.10.20.00.10.10.2-0.3-0.1-0.40.1-0.60.2
Progressive ratio test 2 active lever presses0.60.60.90.80.6-0.9-0.8-0.9-0.40.81.00.7-0.90.8-0.80.7-0.7-0.6-0.9-0.8-1.00.80.50.8
Progressive ratio test 2 breakpoint0.10.10.60.20.0-0.4-0.2-0.40.10.20.60.2-0.50.3-0.30.2-0.1-0.0-0.7-0.2-0.80.6-0.20.6
Progressive ratio test 2 inactive lever presses0.30.40.90.70.5-0.6-0.4-0.6-0.40.40.80.6-0.70.5-0.50.4-0.3-0.3-0.9-0.4-0.90.90.10.8
Incentive Sensitization - Responses0.10.10.3-0.3-0.30.20.20.20.5-0.3-0.2-0.30.3-0.30.3-0.30.30.30.20.30.2-0.3-0.5-0.2
Incentive Sensitization - Breakpoint0.20.20.5-0.5-0.40.40.40.40.6-0.4-0.3-0.50.4-0.40.5-0.40.50.50.30.50.2-0.3-0.7-0.2
Sum of active levers in priming session hrs 5-60.30.30.5-0.4-0.30.60.60.60.2-0.5-0.5-0.50.6-0.50.6-0.50.50.40.60.20.7-0.5-0.3-0.6
Progressive ratio1.41.62.01.11.2-1.3-1.3-1.3-1.11.31.21.3-1.21.4-1.41.4-1.3-1.3-1.2-1.4-1.11.21.31.1
Food seeking constrained by brief footshock1.82.22.9-1.4-1.21.71.51.71.2-1.5-1.5-1.41.6-1.61.5-1.51.41.41.71.51.6-1.3-1.3-1.4
Seeking ratio, punishment vs. effort2.63.13.7-1.5-1.61.91.81.91.6-1.8-1.8-1.81.9-1.91.9-1.81.71.71.91.81.7-1.8-1.6-1.8
Retroperitoneal fat weight2.58.210.02.52.5-3.0-3.0-3.0-2.83.02.83.0-3.03.1-3.23.1-3.0-3.0-2.8-2.9-2.72.23.02.5
Reaction time number correct1.31.93.61.91.9-1.3-1.4-1.3-1.81.41.21.4-1.11.3-1.31.4-1.5-1.5-0.7-1.4-0.81.01.50.6
Reaction time mean minus median1.92.64.7-2.0-2.21.51.61.52.1-1.5-1.8-1.61.5-1.41.1-1.41.51.51.31.61.6-1.7-1.4-1.5
Reaction time mean minus median AUC2.43.15.5-2.2-2.31.71.91.72.2-1.8-1.6-1.81.3-1.81.6-2.02.01.90.92.01.1-1.3-1.8-1.2
Reaction time num false alarms0.70.91.40.91.0-0.9-0.9-0.9-0.61.00.90.9-1.01.0-1.11.1-1.0-1.1-0.8-1.0-0.80.61.20.9
Reaction time num false alarms AUC0.81.22.11.01.1-1.0-1.1-1.1-0.71.20.91.1-1.01.2-1.31.3-1.2-1.3-0.8-1.2-0.80.51.50.8
Reaction time trials correct on left1.31.93.61.91.9-1.3-1.4-1.3-1.81.41.21.4-1.11.3-1.31.4-1.5-1.5-0.7-1.4-0.81.01.50.6
Reaction time trials on left1.21.83.41.81.9-1.2-1.4-1.2-1.81.41.21.4-1.11.3-1.21.4-1.5-1.5-0.7-1.4-0.81.11.50.7
Reaction time mean1.62.34.1-2.0-2.01.41.51.41.9-1.6-1.4-1.51.3-1.61.5-1.71.71.51.01.61.0-1.1-1.5-0.9
Reaction time mean AUC0.81.12.4-1.5-1.60.91.00.91.4-1.1-0.9-1.00.8-1.11.0-1.21.21.10.51.20.5-0.6-1.1-0.5
Median of all reaction times0.81.12.1-1.4-1.41.01.11.01.3-1.2-0.9-1.10.9-1.11.1-1.21.31.10.71.20.5-0.6-1.1-0.5
Reaction time omissions0.00.00.1-0.2-0.10.00.00.00.0-0.10.1-0.0-0.0-0.10.2-0.10.20.1-0.20.1-0.30.2-0.30.3
Reaction time false alarm rate0.10.10.3-0.00.0-0.3-0.3-0.30.20.40.30.3-0.40.4-0.50.4-0.3-0.4-0.5-0.3-0.40.20.50.6
Reaction time premature initiation rate1.31.73.7-1.3-1.41.21.01.31.4-1.1-1.6-1.31.5-1.10.9-0.90.80.81.81.01.7-1.9-0.8-1.6
Reaction time premature initiations0.40.51.9-0.2-0.30.50.30.60.4-0.3-0.9-0.50.9-0.40.2-0.1-0.00.01.40.21.3-1.40.0-1.3
Std. dev. reaction times1.21.73.4-1.7-1.81.21.31.21.7-1.3-1.3-1.31.1-1.31.1-1.41.41.20.91.40.9-1.0-1.2-1.0
Reaction time trials completed1.21.83.41.81.9-1.2-1.4-1.2-1.81.41.21.4-1.11.3-1.21.4-1.5-1.5-0.7-1.4-0.81.11.50.7
Reaction time trials AUC1.52.14.12.02.0-1.3-1.5-1.3-1.91.51.21.5-1.11.4-1.41.5-1.7-1.6-0.7-1.5-0.71.11.60.7
Run reversals in cocaine runway, females2.02.02.6-1.3-1.11.61.51.51.2-1.5-1.4-1.31.4-1.51.6-1.61.51.61.31.51.3-0.8-1.6-1.1
Run reversals in cocaine runway, males2.82.73.9-1.7-1.71.71.61.71.6-1.7-1.5-1.71.6-1.71.8-1.81.81.81.31.71.1-1.3-2.0-1.3
Latency to leave start box in cocaine runway0.10.10.6-0.5-0.50.00.3-0.00.2-0.10.1-0.0-0.4-0.1-0.0-0.40.40.4-0.80.3-0.60.4-0.10.7
Latency to leave start box in cocaine runway, F0.20.31.0-0.4-0.50.00.3-0.00.1-0.20.4-0.0-0.5-0.20.2-0.60.60.4-1.00.4-1.00.8-0.30.9
Latency to leave start box in cocaine runway, M0.10.10.40.10.1-0.3-0.2-0.3-0.10.4-0.30.3-0.00.4-0.60.6-0.5-0.40.1-0.40.5-0.30.50.0
Std. dev. time between licks in bursts0.60.72.0-0.7-0.70.91.00.90.7-1.0-0.6-0.90.6-0.91.2-1.01.11.20.31.00.3-0.5-1.4-0.3
Total sessions with >9 infusions0.40.52.30.40.7-0.4-0.2-0.5-0.50.20.90.4-0.70.3-0.1-0.00.10.2-1.3-0.1-1.31.5-0.41.0
Short access day 1 total inactive lever presses0.00.10.20.30.4-0.2-0.1-0.2-0.10.10.20.1-0.10.1-0.00.1-0.00.1-0.3-0.1-0.30.3-0.40.4
Short access day 10 total inactive lever presses0.10.10.50.00.0-0.3-0.4-0.3-0.00.30.00.1-0.00.4-0.30.5-0.4-0.40.1-0.50.1-0.70.10.1
Short access day 1 total infusions0.90.93.10.60.6-0.9-0.6-0.9-0.50.61.30.7-1.20.7-0.60.4-0.2-0.2-1.8-0.6-1.81.7-0.01.4
Short access day 10 total infusions0.91.01.81.11.0-1.0-0.9-1.0-1.00.91.21.0-1.01.0-0.90.9-0.8-0.7-1.2-0.9-1.21.30.61.1
Short access total infusions1.61.84.21.01.0-1.3-1.1-1.3-1.11.11.71.2-1.61.2-1.10.9-0.7-0.8-2.0-1.1-2.02.00.61.7
Short access day 1 locomotion0.10.10.4-0.2-0.40.20.30.20.5-0.3-0.1-0.30.1-0.20.3-0.40.50.5-0.20.3-0.20.1-0.60.0
Short access day 10 total locomotion1.11.32.6-0.7-0.51.00.81.01.2-1.1-1.3-1.21.4-1.01.2-0.80.91.01.50.91.4-1.6-1.2-1.3
Short access total locomotion0.20.20.3-0.4-0.30.30.40.30.5-0.4-0.3-0.50.3-0.40.5-0.40.50.50.20.40.2-0.4-0.6-0.3
One hour access (0.3 mA shock)0.50.61.11.11.0-0.8-0.8-0.8-0.70.70.80.8-0.70.7-0.70.6-0.6-0.7-0.7-0.7-0.80.90.70.8
Compulsive drug intake0.20.20.60.10.2-0.4-0.5-0.4-0.40.40.40.5-0.50.4-0.50.3-0.3-0.4-0.5-0.4-0.50.70.50.7
One hour access (shock baseline)0.30.41.51.21.2-0.5-0.6-0.5-0.70.50.50.5-0.30.6-0.40.6-0.6-0.6-0.2-0.6-0.20.30.50.1
Social response proportion1.21.31.8-1.3-1.31.11.11.21.2-1.2-1.0-1.21.0-1.31.2-1.31.21.21.01.20.9-0.9-1.1-1.0
Social responses10.513.515.7-4.0-3.83.73.73.73.8-3.7-3.7-3.83.5-3.83.7-3.83.73.73.33.83.4-3.4-3.6-3.2
Social time1.01.42.30.91.0-1.3-1.2-1.3-0.91.31.01.2-1.21.4-1.51.4-1.3-1.2-1.1-1.2-1.00.61.21.0
Soleus weight6.218.321.83.73.7-4.5-4.4-4.5-3.64.44.44.4-4.64.4-4.74.2-4.2-4.3-4.3-4.2-4.44.04.34.4
Bone: stiffness4.26.69.72.42.2-2.6-2.5-2.6-2.52.52.92.6-3.02.5-2.52.3-2.2-2.2-3.1-2.4-3.03.02.22.6
Tibialis anterior weight1.24.15.21.61.7-2.1-2.1-2.1-1.92.12.12.0-2.22.1-2.32.1-2.0-2.1-2.1-1.9-2.21.52.11.9
Time to tail flick, vehicle, before self-admin2.02.14.5-1.7-1.81.31.51.31.6-1.6-1.0-1.51.1-1.51.8-1.81.91.90.51.20.5-0.4-2.1-0.5
Time to tail flick, vehicle, after self-admin0.20.21.0-0.4-0.30.40.30.40.2-0.2-0.6-0.40.6-0.30.3-0.10.00.10.80.40.8-1.0-0.1-0.9
Time to tail flick, test, before self-admin1.51.52.9-1.4-1.51.11.21.11.7-1.3-1.0-1.30.9-1.21.2-1.31.41.40.61.60.5-0.8-1.6-0.5
Time to tail flick, test, after self-admin0.20.20.7-0.5-0.40.40.50.40.4-0.5-0.2-0.40.2-0.50.5-0.70.70.7-0.10.5-0.10.1-0.80.1
Delta time to tail flick, vehicle, before/after SA1.31.33.31.31.4-1.0-1.3-1.0-1.31.30.71.1-0.81.2-1.41.5-1.6-1.6-0.2-1.0-0.20.11.80.2
Delta time to tail flick, test, before/after SA0.10.10.30.20.20.20.00.2-0.3-0.0-0.3-0.00.3-0.10.00.0-0.1-0.10.5-0.20.5-0.20.3-0.5
Tibia length1.13.14.7-1.7-1.61.81.71.82.1-1.6-2.0-1.81.8-1.81.6-1.61.51.31.81.62.1-2.2-1.1-1.9
Ambulatory time before self-admin0.20.20.4-0.2-0.30.60.60.60.1-0.6-0.4-0.40.6-0.60.6-0.60.50.50.50.60.5-0.1-0.4-0.5
Ambulatory time after self-admin0.00.00.2-0.00.00.20.20.2-0.0-0.2-0.0-0.10.2-0.20.2-0.30.30.30.1-0.00.20.5-0.20.1
Bone: tissue strength4.44.35.52.12.1-2.2-2.1-2.2-2.42.02.32.1-2.22.0-1.91.9-1.8-1.7-2.3-1.9-2.32.31.62.0
Total heroin consumption2.73.13.7-1.9-1.71.91.81.91.5-1.8-1.8-1.71.8-1.91.8-1.91.81.81.71.81.7-1.5-1.7-1.4
Bone: trabecular number1.01.62.9-1.7-1.61.31.51.31.3-1.4-1.0-1.30.8-1.41.4-1.61.61.50.51.60.5-0.4-1.4-0.2
Bone: trabecular spacing0.81.12.41.51.4-0.9-1.2-0.9-1.01.10.40.9-0.31.1-1.11.4-1.5-1.40.3-1.30.2-0.21.2-0.4
Bone: trabecular thickness0.80.91.8-1.3-1.30.40.80.30.5-0.70.4-0.4-0.5-0.60.6-1.11.31.2-1.30.9-1.31.1-1.21.3
Bone: trabecular tissue density6.69.310.53.12.9-3.2-3.2-3.2-2.93.23.13.2-3.03.2-3.23.1-3.2-3.2-2.8-3.2-2.82.83.12.5
Water consumed over 24 hours0.70.82.60.60.6-0.8-0.7-0.8-0.90.71.10.8-1.10.7-0.60.5-0.4-0.5-1.3-0.6-1.31.50.51.6
Number of responses in last shaping day0.70.81.4-0.8-0.60.80.90.81.0-0.9-0.9-0.90.9-0.80.9-0.80.91.00.70.80.7-0.8-1.2-0.7