Hub : Genes

Stap1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Eye	gene expression	Stap1	0.35	0.18	9.7e-03	0.18	0.03	0.06	0.18	1.0e-03	1.1e-01	5.2e-02	1.0e-03
2	IL	alternative TSS	XM_017599182.3	0.12	0.08	3.8e-03	0.11	0.13	0.13	0.13	1.2e-03	5.7e-04	4.3e-04	5.3e-04
3	Adipose	gene expression	Stap1	0.13	0.07	1.0e-05	0.02	0.05	0.04	0.05	3.3e-03	3.5e-06	8.0e-06	3.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.6	1.0	1.9	1.4	0.5	-0.8
Area under the delay curve	0.9	1.0	2.1	1.4	-0.3	-0.9
BMI with tail	1.7	5.8	8.2	2.8	2.9	-1.1
BMI without tail	0.8	2.6	5.4	1.4	2.3	-0.6
Body weight	0.2	0.9	1.2	1.1	0.7	-0.9
Weight adjusted by age	1.0	1.5	2.2	1.2	1.5	-0.8
Bone surface	0.4	0.7	1.2	1.1	0.4	-0.8
Bone volume	0.3	0.5	1.2	1.1	-0.4	-0.5
Breakpoint value in progressive ratio session	0.4	0.5	0.9	-0.4	-0.7	0.9
Number of licking bursts	0.3	0.5	0.7	0.8	0.5	-0.7
Context. condit. distance diff. score	1.5	1.8	4.0	-2.0	-0.1	1.2
Locomotion velocity, session 1	0.7	0.8	2.2	0.3	0.4	-1.5
Locomotion distance, session 1	0.0	0.1	0.1	-0.4	-0.1	-0.2
Locomotion velocity, session 2	0.0	0.0	0.0	0.2	0.1	0.2
Locomotion distance, session 2	0.1	0.1	0.2	0.2	-0.1	-0.4
Locomotion velocity, session 3	0.2	0.3	0.5	0.6	-0.7	0.0
Locomotion distance, session 3	0.5	0.5	1.5	1.2	0.3	0.0
Stereotopy head waving bouts, day 3	0.3	0.3	0.5	-0.3	0.6	-0.7
Stereotopy head waving duration, day 3	0.6	0.7	2.2	0.3	-0.1	-1.5
Locomotion velocity, session 7	1.1	1.2	2.2	0.2	-1.5	-1.1
Locomotion distance, session 7	0.6	0.8	1.7	-0.8	-1.3	0.3
Stereotopy head waving bouts, day 7	0.1	0.1	0.4	0.2	0.1	-0.6
Stereotopy head waving duration, day 7	0.4	0.4	0.7	0.7	0.3	-0.8
Locomotion velocity, session 8	0.0	0.0	0.1	0.0	0.1	0.2
Locomotion distance, session 8	0.6	0.9	2.4	-1.6	-0.4	0.2
Degree of sensitization distance	3.1	3.2	6.4	-2.5	-1.5	1.0
Degree of sensitization stereotypy	0.1	0.1	0.2	-0.4	-0.2	0.4
Conditioned locomotion	0.8	0.9	1.8	-0.0	1.0	1.3
Cocaine response after cond. corrected	0.7	0.9	1.8	-0.9	-1.3	-0.2
Cocaine response after cond. not corrected	0.5	0.6	1.1	-0.7	-1.1	-0.6
Cocaine response before conditioning	0.5	0.6	0.9	0.7	0.9	-0.8
Saline control response	0.6	0.8	1.5	-0.8	-0.5	1.2
Bone: connectivity density	0.9	1.4	2.0	1.4	1.2	-1.0
Bone: cortical apparent density	0.5	0.7	2.0	-1.4	-0.2	-0.4
Bone: cortical area	0.5	0.8	1.4	0.8	-0.7	-1.2
Bone: cortical porosity	0.5	0.5	1.4	0.0	1.2	0.3
Bone: cortical porosity	1.0	1.0	2.9	0.4	1.7	-0.1
Bone: cortical thickness	0.4	0.7	1.1	1.1	1.0	-0.3
Bone: cortical thickness	0.0	0.0	0.1	-0.3	-0.1	0.0
Bone: cortical tissue density	0.5	0.7	1.9	-1.4	-0.2	-0.4
Condit. Reinf. active minus inactive responses	1.1	1.3	1.7	-1.3	1.0	1.1
Condit. Reinf. active-inactive response ratio	1.6	1.7	4.6	-0.5	2.1	0.5
Condit. Reinf. active responses	1.1	1.4	3.0	-1.7	-0.0	1.1
Condit. Reinf. inactive responses	1.3	1.6	2.8	-1.3	-1.7	0.5
Incentive salience index mean	1.4	1.7	2.8	-1.5	0.3	1.7
Condit. Reinf. lever presses	0.7	1.0	2.7	-0.6	0.1	1.7
Condit. Reinf. active minus inactive responses	0.0	0.1	0.1	-0.3	-0.1	0.3
Condit. Reinf. active-inactive response ratio	0.3	0.4	0.7	-0.8	-0.4	-0.6
Condit. Reinf. active responses	0.1	0.2	0.4	-0.1	-0.0	0.7
Condit. Reinf. inactive responses	0.4	0.5	0.9	0.7	0.0	0.9
Condit. Reinf. lever presses	0.6	0.8	1.9	1.4	-0.7	0.2
Condit. Reinf. lever reinforcers received	0.2	0.3	0.9	-0.1	-0.1	1.0
Conditioned reinforcement - actives	0.0	0.1	0.2	0.5	0.1	-0.0
Conditioned reinforcement - inactives	1.0	1.4	1.8	-1.0	-1.2	1.3
Conditioned locomotion	0.4	0.6	1.1	0.8	0.0	-1.0
Patch foraging indifference point 0 sec	0.2	0.4	0.6	-0.7	-0.8	-0.1
Patch foraging indifference point AUC	2.6	3.8	5.6	-1.9	-2.4	1.5
Delay disc. indifference point, 0s delay	0.7	0.7	1.2	1.1	0.1	-1.0
Delay disc. indifference point, 16s delay	1.1	1.3	2.1	1.4	0.7	-1.1
Delay disc. indifference point, 2s delay	1.7	1.9	5.6	-0.1	-2.4	-0.1
Delay disc. indifference point, 24s delay	0.0	0.0	0.0	-0.2	0.2	-0.1
Delay disc. indifference point, 4s delay	1.0	1.0	1.6	0.8	-0.9	-1.2
Delay disc. indifference point, 8s delay	2.0	2.4	4.4	2.1	1.0	-1.3
Indifference point function ln k	1.1	2.0	2.7	1.6	1.5	-1.0
Indifference point function log k	1.1	2.0	2.7	1.6	1.5	-1.0
Patch foraging total patch changes 0 sec	0.3	0.5	0.9	-0.9	-0.8	-0.0
Patch foraging total patch changes 12 sec	0.2	0.3	0.5	-0.5	-0.7	0.5
Patch foraging total patch changes 18 sec	1.3	1.9	4.0	-2.0	-0.9	1.0
Patch foraging total patch changes 24 sec	1.0	1.7	2.9	-1.7	-1.2	0.9
Patch foraging total patch changes 6 sec	1.0	1.5	4.0	-0.6	-2.0	-0.0
Patch foraging time to switch 0 sec	1.8	3.6	5.9	2.1	2.4	-0.8
Patch foraging water rate 0 sec	0.9	1.9	3.0	-1.6	-1.7	0.1
Patch foraging water rate 12 sec	0.3	0.7	1.1	-1.1	-0.5	0.8
Patch foraging water rate 18 sec	0.2	0.4	0.9	-0.3	-1.0	-0.1
Patch foraging water rate 24 sec	0.6	0.8	1.1	-0.8	-1.0	0.8
Patch foraging water rate 6 sec	1.4	2.0	3.7	-1.9	-1.4	0.5
Seeking ratio, delayed vs. immediate footshock	3.4	4.2	8.4	-2.9	-0.4	2.0
Distance traveled before self-admin	1.1	1.5	3.3	1.8	0.9	-0.6
Distance traveled after self-admin	1.8	2.3	3.2	-0.9	-1.8	1.7
Extensor digitorum longus weight	3.7	14.6	37.0	2.5	6.1	0.6
Bone: elastic displacement	1.0	1.2	1.7	-1.3	0.6	1.3
Bone: elastic work	0.2	0.2	0.3	0.4	0.5	-0.4
Bone: endosteal estimation	0.8	1.7	3.9	-0.6	-2.0	-0.8
Bone: endosteal perimeter	1.1	2.4	3.9	1.4	-1.0	-2.0
Epididymis fat weight	0.1	0.3	0.7	0.2	0.1	-0.8
Delta time in closed arm before/after self-admin	0.6	0.6	1.0	0.7	1.0	-0.4
Delta time in open arm before/after self-admin	0.4	0.4	0.6	0.8	-0.4	-0.7
Diff in mean of infusions in LGA sessions	0.4	0.4	1.2	-0.3	0.2	1.1
Delay discount exponential model param	0.7	0.8	1.4	-1.2	0.5	0.8
Extinction: sum of active levers before priming	0.2	0.2	0.4	-0.2	0.6	-0.6
Active lever presses in extinction session 6	0.4	0.4	0.8	0.3	-0.9	-0.5
Bone: final force	0.6	0.9	2.1	1.4	-0.1	-0.9
Bone: final moment	0.6	0.9	1.6	1.3	-0.1	-1.1
Food consumed during 24 hour testing period	0.8	1.1	1.9	1.1	-1.4	0.0
Glucose	1.2	1.9	3.0	-1.7	-1.6	0.2
Heart weight	0.6	1.0	2.4	0.7	1.6	-0.2
Delay discount hyperbolic model param	0.8	0.9	1.4	-1.2	0.8	0.7
Intermittent access intake day 1-15 change	0.4	0.8	1.7	1.3	0.4	0.7
Intermittent access intake escalation	0.5	1.0	1.9	1.4	0.8	0.6
Intermittent access intake escalation 2	0.8	1.0	2.8	1.7	-0.3	-0.1
Intermitt. access day 1 inactive lever presses	0.7	2.6	4.3	-1.0	-1.6	2.1
Intermitt. access day 15 inactive lever presses	0.6	1.3	3.8	-0.4	-1.9	0.0
Intermitt. access escalation Index	0.2	0.3	0.8	-0.2	0.9	-0.1
Intermittent access day 1 total infusions	0.2	0.3	0.7	0.3	-0.5	-0.8
Intermittent access day 15 total infusions	0.2	0.3	0.6	0.7	-0.3	0.3
Intermittent access terminal intake (last 3 days)	0.4	0.5	0.8	0.9	-0.8	0.1
Intermittent access total infusions	0.1	0.2	0.3	0.5	-0.4	-0.4
Intermittent access day 1 locomotion	0.3	0.3	0.8	-0.2	-0.9	-0.4
Intermittent access day 15 total locomotion	0.0	0.0	0.0	0.2	-0.1	-0.1
Intermittent access total locomotion	0.3	0.4	0.8	0.6	-0.1	-0.9
Intermittent access standard deviation	0.4	0.8	1.9	0.6	-1.4	0.3
Left kidney weight	0.1	0.5	0.7	0.8	0.4	-0.8
Right kidney weight	0.4	1.8	3.1	1.5	-0.4	-1.8
Cocaine induced anxiety	1.1	1.6	2.6	1.2	0.8	-1.6
Post-drug Anxiety	0.5	0.6	0.9	0.9	-0.2	-0.9
Baseline Anxiety	2.3	2.7	4.3	-1.3	-1.4	2.1
Tail length	0.3	1.3	1.9	-1.4	-1.2	0.8
Length with tail	0.4	1.9	2.8	-1.5	-1.7	0.8
Length without tail	0.3	1.1	1.8	-1.1	-1.3	0.5
Times rat made contact with spout	1.1	1.2	2.4	1.6	-1.0	-0.5
Lifetime Intake	0.3	0.3	0.5	0.7	-0.1	-0.7
Liver weight, left	1.5	2.5	2.9	1.7	-1.3	-1.7
Liver weight, right	0.7	1.3	2.0	0.3	-1.4	-1.3
Locomotor activity	1.4	2.2	3.6	1.7	-0.2	-1.9
Locomotor testing distance	0.4	0.8	1.0	0.8	0.8	-1.0
Locomotor testing rearing	0.2	0.4	0.6	-0.7	0.8	0.3
Locomotion in novel chamber	1.4	1.7	4.3	-2.1	-0.4	0.9
Locomotion in novel chamber post-restriction	0.7	1.1	2.0	-1.4	-1.0	0.4
Fecal boli incidents, locomotor time 1	0.8	1.1	2.5	1.0	1.6	0.0
Change in fecal boli incidents, locomotor task	0.6	0.6	1.6	-1.3	-0.2	0.2
Time >=10cm from walls, locomotor time 1	0.9	1.0	2.1	-1.4	0.9	-0.2
Bouts of movement, locomotor time 1	0.4	0.4	0.6	0.7	0.8	-0.4
Total resting periods, locomotor time 1	0.3	0.3	0.5	0.5	0.5	-0.7
Rest time, locomotor task time 1	0.1	0.2	0.4	-0.2	-0.6	0.3
Distance moved, locomotor task time 1	0.0	0.1	0.1	0.2	0.3	0.2
Vertical activity count, locomotor time 1	0.3	0.6	1.2	0.7	-0.5	-1.1
Time >=10cm from walls, locomotor time 2	0.3	0.5	0.8	-0.7	0.9	0.3
Bouts of movement, locomotor time 2	0.2	0.3	0.6	-0.8	-0.5	0.0
Total resting periods, locomotor time 2	0.1	0.2	0.3	-0.6	-0.5	-0.1
Rest time, locomotor task time 2	0.3	0.4	0.9	-0.9	-0.2	0.5
Distance moved, locomotor task time 2	1.9	2.2	4.4	2.1	1.5	-0.3
Vertical activity count, locomotor time 2	1.0	1.4	2.9	1.7	0.4	-1.1
Light reinforcement 1	0.3	0.6	1.6	1.3	-0.5	-0.2
Light reinforcement 2	1.0	1.5	3.5	1.9	0.4	-0.9
Bone: marrow area	0.7	1.6	3.8	-0.6	-1.9	-0.8
Bone: maximum diameter	0.8	1.6	3.4	0.8	-0.8	-1.8
Bone: maximum force	0.5	0.8	1.4	1.2	-0.3	-1.0
Bone: maximum moment	0.5	0.9	1.7	1.0	-0.4	-1.3
Mean time between licks in bursts	2.2	5.3	9.1	3.0	2.3	-1.3
Mean num. licks in bursts	0.4	0.7	1.9	-0.0	-1.4	0.3
Cd content in liver	1.5	1.7	3.0	1.1	1.7	-0.8
Co content in liver	0.3	0.3	0.6	-0.2	0.5	-0.8
Cu content in liver	0.2	0.2	0.3	-0.4	0.4	0.6
Fe content in liver	0.7	0.9	1.2	0.7	1.1	-0.9
K content in liver	0.7	0.6	1.2	-1.1	-0.2	0.8
Mg content in liver	0.1	0.1	0.1	-0.3	-0.2	0.2
Mn content in liver	2.4	2.6	4.6	-2.2	0.4	1.7
Na content in liver	0.9	1.0	2.2	-1.5	-0.8	0.4
Rb content in liver	1.2	1.4	2.5	-1.6	1.2	-0.5
Se content in liver	1.6	1.8	5.3	0.5	-0.1	2.3
Sr content in liver	0.3	0.3	0.5	-0.4	0.7	0.4
Zn content in liver	0.3	0.4	0.9	0.2	0.4	0.9
Bone: minimum diameter	2.1	3.8	8.2	-0.4	-2.9	-1.7
Time in familiar zone, hab. session 1	0.5	0.5	1.2	-0.4	0.0	1.1
Time in novel zone, hab. session 1	0.6	0.6	1.7	0.1	0.2	-1.3
Total zone transitions, hab. session 1	0.2	0.3	0.6	-0.5	-0.3	0.8
Total locomotion distance, hab. session 1	0.4	0.6	1.2	-0.2	-1.1	0.7
Locomotion velocity, hab. session 1	0.5	0.7	1.1	-0.3	-1.0	0.9
Time in familiar zone, hab. session 2	0.5	0.5	1.1	1.0	0.7	-0.0
Time in novel zone, hab. session 2	0.5	0.5	0.9	-1.0	-0.3	-0.6
Total zone transitions, hab. session 2	0.2	0.2	0.5	0.7	0.2	-0.5
Total locomotion distance, hab. session 2	0.1	0.2	0.3	0.3	-0.6	-0.3
Locomotion velocity, hab. session 2	0.1	0.2	0.3	0.4	-0.6	-0.2
Novel to familiar place preference ratio	0.1	0.1	0.3	-0.1	-0.5	0.1
Novelty place preference	0.0	0.0	0.1	0.0	-0.4	-0.0
Time in novel zone, NPP test	0.1	0.1	0.3	-0.2	-0.5	0.0
Total zone transitions, NPP test	0.2	0.3	0.6	-0.4	-0.1	-0.8
Total locomotion distance, NPP test	0.1	0.2	0.3	-0.4	-0.0	-0.5
Locomotion velocity, NPP test	0.1	0.1	0.2	-0.3	0.2	-0.4
Intraocular pressure	4.2	6.1	9.2	3.0	0.2	-3.0
Delta distance traveled before/after self-admin	3.7	3.9	5.0	-2.2	-2.1	1.6
Delta ambulatory time before/after self-admin	1.8	2.2	4.0	-2.0	-1.4	0.9
Parametrial fat weight	1.0	2.3	4.1	0.3	-2.0	-1.6
Pavlov. Cond. lever latency	1.3	1.7	3.0	1.3	0.6	-1.7
Pavlov. Cond. magazine entry latency	1.7	2.1	5.6	-0.9	0.2	2.4
Pavlov. Cond. change in total contacts	2.9	3.0	5.9	-1.8	0.2	2.4
Pavlov. Cond. index score	2.3	2.9	6.3	-1.5	-0.1	2.5
Pavlov. Cond. latency score	2.1	2.6	5.7	-1.4	-0.3	2.4
Pavlov. Cond. lever contacts	1.3	1.5	3.1	-1.1	-0.6	1.8
Pavlov. Cond. magazine entry number	2.2	2.8	5.3	1.8	-0.1	-2.3
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.8	-0.9	-0.1	-0.0
Pavlov. Cond. lever-magazine prob. diff.	2.4	3.0	6.4	-1.5	-0.3	2.5
Pavlov. Cond. response bias	1.6	2.0	4.2	-1.3	-0.2	2.0
Pavlov. Cond. lever latency	1.3	1.8	4.9	-2.2	-0.6	0.3
Pavlov. Cond. magazine entry latency	1.0	1.2	1.9	1.4	1.1	-0.8
Pavlov. Cond. change in total contacts	0.7	1.2	2.6	1.6	1.0	-0.1
Pavlov. Cond. index score	1.3	1.8	4.3	2.1	1.0	-0.3
Pavlov. Cond. latency score	1.3	1.8	3.8	2.0	1.2	-0.2
Pavlov. Cond. lever contacts	1.5	2.0	5.8	2.4	0.2	-0.5
Pavlov. Cond. magazine entry number	1.7	2.1	2.8	-1.7	-1.5	1.0
Pavlov. Cond. intertrial magazine entries	0.7	1.1	2.3	-0.7	-1.5	0.7
Pavlov. Cond. lever-magazine prob. diff.	1.4	1.9	4.6	2.2	1.0	-0.3
Pavlov. Cond. response bias	1.3	1.8	4.7	2.2	0.6	-0.5
Time in closed arm before self-admin	2.6	3.4	5.2	-2.3	-1.0	2.0
Time in closed arm after self-admin	1.6	1.7	4.1	-0.9	0.4	2.0
Time in open arm before self-admin	0.3	0.4	0.7	0.3	0.8	-0.6
Time in open arm after self-admin	1.1	1.2	2.4	0.5	-0.9	-1.5
Bone: periosteal estimation	0.6	1.3	2.2	0.2	-1.5	-1.2
Bone: periosteal perimeter	1.3	2.2	3.9	1.4	-0.9	-2.0
Bone: post-yield work	0.6	0.8	2.2	-0.5	-0.1	-1.5
Progressive ratio test 1 active lever presses	1.0	1.2	2.2	1.5	0.8	-1.0
Progressive ratio test 1 breakpoint	0.9	1.1	2.0	1.4	0.7	-0.9
Progressive ratio test 1 inactive lever presses	1.0	1.5	3.4	-0.5	-1.8	0.9
Progressive ratio test 2 active lever presses	1.6	1.8	4.8	2.2	-0.0	-0.8
Progressive ratio test 2 breakpoint	1.6	1.8	4.7	2.2	0.1	-0.8
Progressive ratio test 2 inactive lever presses	0.4	0.6	1.3	0.1	-1.1	0.8
Incentive Sensitization - Responses	0.8	1.2	3.4	1.8	-0.1	-0.3
Incentive Sensitization - Breakpoint	0.9	1.2	3.5	1.9	-0.0	-0.3
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	0.2	0.0	-0.1
Progressive ratio	0.7	1.2	3.4	1.9	0.2	-0.0
Food seeking constrained by brief footshock	0.1	0.1	0.3	0.0	0.6	-0.1
Seeking ratio, punishment vs. effort	0.7	1.0	2.5	-1.6	-0.3	-0.5
Retroperitoneal fat weight	0.4	1.8	4.3	0.6	-0.9	-2.1
Reaction time number correct	0.6	1.1	3.0	0.7	0.1	-1.7
Reaction time mean minus median	0.2	0.4	0.7	-0.8	0.6	-0.4
Reaction time mean minus median AUC	0.1	0.3	0.4	-0.4	0.4	-0.7
Reaction time num false alarms	0.8	1.1	1.8	-1.3	0.1	1.3
Reaction time num false alarms AUC	0.8	1.3	2.0	-1.4	0.4	1.3
Reaction time trials correct on left	0.6	1.1	3.0	0.7	0.1	-1.7
Reaction time trials on left	0.6	1.2	3.1	0.7	0.1	-1.7
Reaction time mean	0.2	0.2	0.6	0.1	0.8	-0.3
Reaction time mean AUC	0.2	0.3	0.9	-0.0	1.0	-0.1
Median of all reaction times	0.2	0.3	0.7	0.3	0.8	-0.2
Reaction time omissions	0.4	0.6	1.6	0.1	1.3	-0.3
Reaction time false alarm rate	1.4	1.9	3.6	-1.4	0.3	1.9
Reaction time premature initiation rate	1.0	1.4	3.9	0.2	-0.4	2.0
Reaction time premature initiations	0.2	0.4	0.7	0.5	-0.5	0.8
Std. dev. reaction times	0.1	0.2	0.5	-0.4	0.7	-0.4
Reaction time trials completed	0.6	1.2	3.1	0.7	0.1	-1.7
Reaction time trials AUC	0.8	1.5	3.8	0.8	0.1	-2.0
Run reversals in cocaine runway, females	1.2	1.2	2.0	1.0	-0.9	-1.4
Run reversals in cocaine runway, males	0.3	0.3	0.9	1.0	0.2	-0.3
Latency to leave start box in cocaine runway	2.4	2.8	5.3	-1.7	-2.3	0.2
Latency to leave start box in cocaine runway, F	5.3	6.1	9.6	-2.9	-3.1	0.4
Latency to leave start box in cocaine runway, M	0.4	0.4	1.1	1.0	-0.0	-0.1
Std. dev. time between licks in bursts	0.9	1.2	2.4	1.0	1.6	0.2
Total sessions with >9 infusions	2.5	3.0	4.0	1.7	1.4	-2.0
Short access day 1 total inactive lever presses	0.6	0.8	1.6	-0.3	-1.3	0.8
Short access day 10 total inactive lever presses	0.4	0.9	1.3	-0.7	-1.1	0.9
Short access day 1 total infusions	0.5	0.6	1.3	0.6	-0.4	-1.2
Short access day 10 total infusions	0.5	0.6	1.1	0.7	0.4	-1.0
Short access total infusions	1.2	1.5	2.8	1.2	0.5	-1.7
Short access day 1 locomotion	1.2	1.5	3.1	0.8	0.7	-1.8
Short access day 10 total locomotion	0.2	0.5	1.3	1.1	0.0	-0.3
Short access total locomotion	1.4	1.6	3.3	1.1	0.6	-1.8
One hour access (0.3 mA shock)	0.2	0.3	0.5	-0.1	-0.7	0.6
Compulsive drug intake	1.3	1.6	2.5	-1.6	-0.9	1.2
One hour access (shock baseline)	0.3	0.5	1.0	1.0	-0.1	-0.7
Social response proportion	1.1	1.2	2.8	-1.0	-1.7	-0.2
Social responses	1.4	1.8	2.4	-1.5	-1.5	0.9
Social time	1.1	1.5	1.7	-1.3	-1.1	1.2
Soleus weight	0.8	2.3	5.3	-1.3	0.2	2.3
Bone: stiffness	0.5	0.8	1.4	1.2	-0.9	-0.6
Tibialis anterior weight	1.7	5.9	12.3	2.2	3.5	0.8
Time to tail flick, vehicle, before self-admin	0.7	0.7	2.1	0.0	-1.5	0.2
Time to tail flick, vehicle, after self-admin	1.2	1.6	2.8	-0.9	-1.1	1.7
Time to tail flick, test, before self-admin	1.2	1.2	3.3	-0.5	0.3	1.8
Time to tail flick, test, after self-admin	0.3	0.3	0.8	0.1	-0.9	-0.4
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.0	-0.2	-0.2	0.2
Delta time to tail flick, test, before/after SA	1.0	1.0	1.7	0.3	-1.1	-1.3
Tibia length	0.4	1.0	1.9	1.4	-0.8	-0.7
Ambulatory time before self-admin	1.0	1.5	3.5	1.9	0.7	-0.6
Ambulatory time after self-admin	0.9	1.1	2.2	-0.1	-1.5	1.0
Bone: tissue strength	0.3	0.3	0.9	-0.1	-0.9	-0.2
Total heroin consumption	0.4	0.5	1.0	-0.6	-1.0	0.3
Bone: trabecular number	0.0	0.1	0.1	0.4	0.2	0.1
Bone: trabecular spacing	0.0	0.0	0.0	-0.2	0.1	-0.1
Bone: trabecular thickness	0.9	1.2	3.2	1.8	-0.3	-0.4
Bone: trabecular tissue density	0.2	0.3	0.5	-0.1	0.7	-0.7
Water consumed over 24 hours	1.3	1.8	2.3	1.5	-1.5	-0.8
Number of responses in last shaping day	0.2	0.2	0.5	0.2	0.7	0.1