Hub : Genes

St13

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio NM_031122.2 0.06 0.04 4.0e-06 0.03 0.03 0.04 0.03 1.2e-04 1.3e-04 8.8e-05 1.5e-04
2 Liver isoform ratio NM_031122.2 0.05 0.04 6.3e-05 0.01 0.01 0.01 0.01 2.5e-02 2.6e-02 3.5e-02 5.3e-02
3 Liver isoform ratio XM_063264299.1 0.07 0.05 8.8e-07 0.03 0.03 0.02 0.02 3.3e-04 5.4e-04 1.1e-03 1.6e-03
4 Liver alternative polyA XM_063264299.1 0.08 0.07 8.5e-06 0.04 0.02 0.04 0.02 2.4e-05 1.1e-03 2.9e-05 1.9e-03
5 OFC gene expression St13 0.15 0.09 8.3e-03 0.02 0.03 0 0.01 1.1e-01 6.8e-02 3.0e-01 1.5e-01
6 Liver alternative polyA NM_031122.2 0.05 0.04 4.3e-04 0 0.01 0 0 7.4e-02 3.5e-02 1.0e-01 1.1e-01
7 Adipose alternative polyA NM_031122.2 0.06 0.04 6.5e-07 0.04 0.03 0.03 0.04 3.4e-05 1.5e-04 1.0e-04 7.1e-05
8 Adipose alternative polyA XM_063264299.1 0.07 0.04 2.7e-07 0.04 0.04 0.04 0.04 2.1e-05 6.0e-05 5.1e-05 2.7e-05
9 Brain isoform ratio NM_031122.2 0.02 0.02 4.6e-03 0.01 0.02 0.01 0.01 7.5e-02 8.1e-03 1.5e-02 1.6e-02
10 Adipose isoform ratio XM_063264299.1 0.05 0.03 9.8e-06 0.03 0.03 0.02 0.02 5.0e-04 4.9e-04 5.4e-03 8.6e-04
11 NAcc isoform ratio NM_031122.2 0.03 0.02 1.9e-04 0.03 0.01 0.01 0.02 3.3e-05 1.3e-02 7.4e-03 1.2e-03
12 pVTA alternative polyA NM_031122.2 0.03 0.02 9.0e-03 0.02 0.02 0 0.02 5.6e-03 1.1e-02 1.1e-01 1.3e-02
13 NAcc isoform ratio XM_063264299.1 0.03 0.02 7.2e-05 0.03 0.01 0.01 0.02 1.6e-05 7.8e-03 1.6e-02 8.1e-04
14 Brain alternative polyA XM_063264299.1 0.03 0.02 1.4e-03 0.02 0.02 0.02 0.02 2.3e-03 6.3e-03 4.2e-03 5.8e-03
15 Brain alternative polyA NM_031122.2 0.03 0.02 9.1e-04 0.03 0.02 0.03 0.03 1.6e-03 3.0e-03 1.6e-03 1.7e-03
16 Brain isoform ratio XM_063264299.1 0.02 0.02 6.7e-03 0.02 0.02 0.01 0.01 7.1e-03 1.1e-02 2.9e-02 1.4e-02
17 NAcc alternative polyA NM_031122.2 0.04 0.02 4.7e-06 0.02 0.02 0.02 0.03 1.1e-04 2.6e-04 3.9e-04 2.4e-05
18 NAcc alternative polyA XM_063264299.1 0.04 0.02 1.2e-05 0.02 0.02 0.02 0.03 4.7e-04 2.7e-04 4.9e-04 8.2e-05
19 IC gene expression St13 0.08 0.05 3.1e-03 0.02 0.04 0.04 0.03 5.5e-02 8.2e-03 8.5e-03 2.5e-02
20 pVTA isoform ratio XM_063264299.1 0.05 0.03 1.4e-03 0.04 0.03 0.05 0.05 1.8e-04 2.5e-03 1.4e-04 7.0e-05
21 pVTA mRNA stability St13 0.08 0.04 3.4e-05 0.06 0.06 0.05 0.06 3.1e-05 8.9e-06 5.7e-05 1.5e-05
22 pVTA isoform ratio NM_031122.2 0.04 0.03 2.0e-03 0.05 0.03 0.04 0.05 9.5e-05 2.0e-03 4.2e-04 1.2e-04
23 Liver gene expression St13 0.19 0.09 1.6e-10 0.07 0.08 0.07 0.07 1.3e-08 3.9e-09 2.7e-08 1.1e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.20.41.00.50.4-0.4-0.40.20.70.4-0.40.3-0.70.60.6-0.7-0.70.7-0.70.8-0.90.4-0.11.0-0.0-0.8
Area under the delay curve0.30.40.90.80.9-0.9-0.90.20.70.8-0.80.1-0.80.30.3-0.3-0.60.6-0.60.7-0.6-0.50.1-0.4-0.30.9
BMI with tail0.82.95.1-2.1-2.32.32.3-1.9-1.9-1.91.9-1.72.0-1.6-1.71.61.9-1.91.9-1.61.3-1.10.2-0.30.3-0.8
BMI without tail0.10.21.1-0.2-0.30.30.3-0.20.0-0.40.4-0.00.10.20.1-0.1-0.10.1-0.10.1-0.30.3-0.71.00.7-1.1
Body weight1.25.37.0-2.6-2.62.62.6-2.6-2.6-2.42.4-2.62.6-2.6-2.52.62.7-2.72.7-2.22.0-2.11.0-1.3-0.40.0
Weight adjusted by age0.10.20.90.40.6-0.6-0.60.40.10.4-0.40.3-0.0-0.10.20.3-0.30.3-0.30.2-0.20.00.6-0.7-0.81.0
Bone surface0.40.71.81.01.0-1.0-1.00.41.01.3-1.30.4-1.00.60.4-0.7-0.70.7-0.71.3-1.3-0.00.60.3-0.80.3
Bone volume0.10.10.50.40.3-0.3-0.3-0.00.40.6-0.60.0-0.40.20.1-0.3-0.30.3-0.30.6-0.7-0.00.20.4-0.3-0.3
Breakpoint value in progressive ratio session0.10.10.4-0.1-0.20.20.2-0.5-0.2-0.40.4-0.30.1-0.00.1-0.00.1-0.10.1-0.1-0.0-0.1-0.10.40.1-0.7
Number of licking bursts0.71.22.11.41.4-1.4-1.41.11.31.3-1.31.0-1.20.91.1-1.0-1.01.0-1.01.2-1.20.40.3-0.1-0.61.0
Context. condit. distance diff. score5.97.111.0-3.1-2.92.92.9-2.0-3.2-2.82.8-2.13.2-2.9-2.92.93.0-3.03.0-3.23.3-1.6-0.0-2.20.80.8
Locomotion velocity, session 10.50.61.90.90.9-0.9-0.90.10.61.2-1.2-0.1-0.60.40.4-0.2-0.30.3-0.30.8-0.7-0.80.7-0.8-0.81.4
Locomotion distance, session 13.34.18.02.72.7-2.7-2.71.72.22.8-2.81.5-2.32.12.0-1.9-1.91.9-1.92.4-2.10.60.40.1-0.91.2
Locomotion velocity, session 20.10.10.4-0.3-0.30.30.3-0.6-0.4-0.30.3-0.60.4-0.3-0.30.40.3-0.30.3-0.30.3-0.60.2-0.2-0.2-0.1
Locomotion distance, session 23.04.27.12.62.5-2.5-2.51.22.52.3-2.31.2-2.52.22.1-2.1-2.02.0-2.02.6-2.70.41.01.1-1.70.2
Locomotion velocity, session 30.10.20.9-0.2-0.10.10.10.4-0.3-0.00.00.30.4-0.4-0.50.40.4-0.40.4-0.40.60.10.1-0.9-0.00.9
Locomotion distance, session 31.51.73.51.61.7-1.7-1.71.91.21.9-1.91.6-1.21.11.0-1.0-0.90.9-0.91.1-0.80.9-0.2-0.70.01.6
Stereotopy head waving bouts, day 30.70.81.9-1.0-1.01.01.0-1.4-0.9-1.11.1-1.30.8-0.9-1.00.90.9-0.90.9-0.80.6-1.10.3-0.3-0.1-0.3
Stereotopy head waving duration, day 33.13.75.9-2.3-2.42.42.4-2.4-2.0-2.42.4-2.32.0-1.9-2.01.91.9-1.91.9-2.01.7-1.70.7-0.5-0.3-0.7
Locomotion velocity, session 70.20.20.6-0.4-0.30.30.3-0.2-0.5-0.20.2-0.30.5-0.4-0.50.50.5-0.50.5-0.50.6-0.40.3-0.8-0.20.7
Locomotion distance, session 70.10.10.60.20.3-0.3-0.3-0.10.00.3-0.3-0.2-0.10.0-0.10.20.2-0.20.20.10.0-0.50.7-0.6-0.80.7
Stereotopy head waving bouts, day 71.71.93.1-1.6-1.51.51.5-0.9-1.6-1.51.5-1.01.7-1.5-1.51.51.5-1.51.5-1.71.8-0.80.2-1.30.10.6
Stereotopy head waving duration, day 72.02.44.2-1.9-1.91.91.9-1.0-1.9-1.91.9-1.01.9-1.5-1.51.51.5-1.51.5-2.02.1-0.3-0.6-0.61.1-0.4
Locomotion velocity, session 81.21.42.8-1.1-1.01.01.0-1.5-1.2-1.01.0-1.51.2-1.3-1.41.41.4-1.41.4-1.00.9-1.70.7-1.2-0.50.8
Locomotion distance, session 80.50.71.4-0.9-0.90.90.9-0.5-1.1-0.90.9-0.61.1-0.8-0.80.80.9-0.90.9-1.11.2-0.4-0.2-0.70.40.2
Degree of sensitization distance3.23.35.6-2.2-2.32.32.3-2.4-2.0-2.32.3-2.11.8-1.7-1.71.71.7-1.71.7-1.81.6-1.40.3-0.00.1-1.3
Degree of sensitization stereotypy1.21.32.4-1.3-1.21.21.2-0.6-1.4-1.21.2-0.81.4-1.2-1.21.31.3-1.31.3-1.51.5-0.60.2-1.10.10.6
Conditioned locomotion0.50.61.1-0.8-0.80.80.8-0.6-0.9-0.80.8-0.60.9-0.7-0.80.70.8-0.80.8-1.01.0-0.5-0.2-0.60.50.1
Cocaine response after cond. corrected0.10.20.3-0.4-0.40.40.4-0.5-0.5-0.50.5-0.60.4-0.5-0.40.40.4-0.40.4-0.50.5-0.40.1-0.2-0.0-0.2
Cocaine response after cond. not corrected0.10.10.5-0.3-0.40.40.4-0.3-0.3-0.60.6-0.30.2-0.1-0.10.10.1-0.10.1-0.50.40.00.00.30.0-0.7
Cocaine response before conditioning0.30.41.10.40.3-0.3-0.30.70.50.1-0.10.8-0.50.90.7-0.8-0.70.7-0.70.3-0.31.0-0.50.90.4-0.8
Saline control response0.10.21.00.0-0.00.00.00.6-0.10.2-0.20.50.10.20.2-0.3-0.30.3-0.3-0.10.30.7-0.90.11.0-0.2
Bone: connectivity density0.00.10.30.20.2-0.2-0.2-0.10.30.1-0.1-0.0-0.30.20.1-0.2-0.20.2-0.20.4-0.5-0.00.20.4-0.3-0.3
Bone: cortical apparent density1.11.52.81.41.3-1.3-1.31.71.41.5-1.51.6-1.21.21.3-1.2-1.21.2-1.21.3-1.21.2-0.20.2-0.10.7
Bone: cortical area1.11.73.8-1.4-1.51.51.5-1.9-1.3-1.21.2-1.91.3-1.4-1.41.41.3-1.31.3-0.90.7-1.61.0-0.5-0.8-0.3
Bone: cortical porosity0.70.81.8-1.1-1.21.21.2-0.9-1.0-1.31.3-0.80.9-0.6-0.60.70.6-0.60.6-1.11.0-0.1-0.10.50.3-1.3
Bone: cortical porosity1.92.13.6-1.7-1.81.81.8-1.7-1.6-1.91.9-1.61.5-1.3-1.41.41.4-1.41.4-1.61.5-0.90.30.00.1-1.1
Bone: cortical thickness0.30.42.0-0.5-0.60.60.6-1.0-0.4-0.40.4-0.90.4-0.5-0.50.60.5-0.50.5-0.0-0.2-1.01.4-0.2-1.40.1
Bone: cortical thickness0.50.63.7-0.3-0.30.30.3-1.0-0.1-0.30.3-1.00.2-0.4-0.40.50.4-0.40.40.1-0.3-1.31.8-0.5-1.90.7
Bone: cortical tissue density1.01.42.71.31.3-1.3-1.31.61.31.4-1.41.6-1.21.21.3-1.2-1.11.1-1.11.3-1.21.1-0.10.1-0.20.8
Condit. Reinf. active minus inactive responses0.20.30.80.60.6-0.6-0.60.40.70.7-0.70.4-0.70.40.4-0.3-0.40.4-0.40.8-0.90.00.00.1-0.20.4
Condit. Reinf. active-inactive response ratio0.20.20.4-0.4-0.30.30.3-0.1-0.3-0.20.2-0.20.4-0.5-0.50.60.5-0.50.5-0.30.4-0.3-0.4-0.60.50.6
Condit. Reinf. active responses1.62.02.71.51.3-1.3-1.31.31.61.4-1.41.4-1.51.61.6-1.5-1.51.5-1.51.6-1.61.3-1.11.30.8-0.5
Condit. Reinf. inactive responses3.03.75.82.01.8-1.8-1.81.81.91.7-1.72.0-1.92.42.4-2.4-2.22.2-2.21.7-1.72.0-1.62.01.2-1.3
Incentive salience index mean0.60.71.61.00.9-0.9-0.90.61.11.1-1.10.7-1.00.80.8-0.8-0.80.8-0.81.2-1.30.3-0.30.40.10.2
Condit. Reinf. lever presses0.91.32.21.21.1-1.1-1.10.91.31.3-1.31.0-1.21.21.3-1.2-1.31.3-1.31.4-1.50.8-0.81.00.5-0.4
Condit. Reinf. active minus inactive responses0.30.41.50.50.5-0.5-0.5-0.30.50.9-0.9-0.4-0.5-0.1-0.10.0-0.00.0-0.00.8-0.9-1.00.8-0.7-0.91.2
Condit. Reinf. active-inactive response ratio0.40.42.6-0.1-0.00.00.0-0.80.10.1-0.1-0.8-0.1-0.5-0.50.40.4-0.40.40.3-0.5-1.21.5-0.5-1.60.8
Condit. Reinf. active responses0.30.52.2-0.2-0.10.10.1-0.7-0.10.3-0.3-0.80.2-0.7-0.60.60.5-0.50.50.1-0.2-1.41.0-1.2-1.01.5
Condit. Reinf. inactive responses0.40.51.7-0.4-0.40.40.4-0.6-0.5-0.10.1-0.80.6-0.8-0.70.80.8-0.80.8-0.40.5-1.20.6-1.3-0.51.3
Condit. Reinf. lever presses0.40.51.10.80.7-0.7-0.70.40.80.9-0.90.4-0.80.70.7-0.7-0.80.8-0.81.0-1.10.3-0.50.60.4-0.1
Condit. Reinf. lever reinforcers received0.20.31.3-0.0-0.00.00.0-0.60.00.4-0.4-0.7-0.0-0.4-0.40.40.3-0.30.30.3-0.4-1.10.6-0.8-0.61.1
Conditioned reinforcement - actives0.40.72.1-0.7-0.80.80.8-0.8-0.5-0.60.6-0.90.6-0.6-0.50.70.8-0.80.8-0.50.5-1.21.4-1.1-1.51.2
Conditioned reinforcement - inactives0.30.52.10.60.5-0.5-0.5-0.50.61.1-1.1-0.3-0.60.30.2-0.4-0.20.2-0.21.3-1.5-0.70.80.4-1.00.0
Conditioned locomotion1.72.23.7-1.5-1.81.81.8-1.9-1.2-1.41.4-1.81.2-1.3-1.11.21.7-1.71.7-0.90.6-1.71.9-0.6-1.80.0
Patch foraging indifference point 0 sec0.40.82.00.80.6-0.6-0.60.41.00.6-0.60.6-0.91.21.0-1.1-1.01.0-1.01.1-1.30.7-0.21.4-0.0-1.1
Patch foraging indifference point AUC0.91.33.51.41.6-1.6-1.60.71.11.5-1.50.5-1.10.50.6-0.5-0.60.6-0.61.2-1.1-0.51.0-1.0-1.21.9
Delay disc. indifference point, 0s delay1.01.11.9-1.2-1.41.41.4-1.4-1.3-1.01.0-1.21.1-0.8-0.80.80.8-0.80.8-1.00.9-0.6-0.70.41.0-1.3
Delay disc. indifference point, 16s delay1.01.12.31.31.5-1.5-1.50.91.31.4-1.40.7-1.40.70.8-0.6-0.90.9-0.91.2-1.20.20.50.0-0.80.7
Delay disc. indifference point, 2s delay0.10.10.50.20.2-0.2-0.2-0.30.10.2-0.2-0.4-0.20.10.0-0.10.0-0.00.00.1-0.1-0.7-0.2-0.40.20.6
Delay disc. indifference point, 24s delay1.01.25.20.91.3-1.3-1.30.10.71.2-1.2-0.2-0.8-0.3-0.20.5-0.20.2-0.20.8-0.7-1.21.7-1.5-1.92.3
Delay disc. indifference point, 4s delay0.20.20.50.60.5-0.5-0.5-0.10.60.4-0.4-0.1-0.60.40.4-0.4-0.40.4-0.40.6-0.7-0.5-0.1-0.1-0.00.5
Delay disc. indifference point, 8s delay0.70.81.41.11.2-1.2-1.20.71.01.0-1.00.6-1.10.90.7-0.8-1.11.1-1.10.9-0.80.0-0.3-0.10.10.7
Indifference point function ln k0.91.63.1-1.7-1.81.81.8-0.8-1.4-1.61.6-0.61.5-1.1-1.21.01.2-1.21.2-1.51.4-0.0-0.3-0.00.7-0.7
Indifference point function log k0.91.63.1-1.7-1.81.81.8-0.8-1.4-1.61.6-0.61.5-1.1-1.21.01.2-1.21.2-1.51.4-0.0-0.3-0.00.7-0.7
Patch foraging total patch changes 0 sec0.51.02.30.90.7-0.7-0.70.51.10.7-0.70.7-1.11.31.2-1.2-1.21.2-1.21.2-1.30.9-0.41.50.1-1.2
Patch foraging total patch changes 12 sec0.10.10.30.50.5-0.5-0.5-0.10.40.5-0.5-0.1-0.40.40.3-0.2-0.20.2-0.20.5-0.6-0.20.40.0-0.60.1
Patch foraging total patch changes 18 sec0.30.41.20.80.7-0.7-0.7-0.30.70.7-0.7-0.2-0.80.70.7-0.5-0.60.6-0.61.0-1.1-0.40.50.6-0.7-0.4
Patch foraging total patch changes 24 sec0.30.50.91.01.0-1.0-1.00.50.80.9-0.90.5-0.90.80.8-0.7-0.80.8-0.80.8-0.80.2-0.10.3-0.10.1
Patch foraging total patch changes 6 sec0.81.23.51.31.2-1.2-1.2-0.11.31.2-1.20.0-1.31.11.0-1.0-1.01.0-1.01.7-1.9-0.31.00.7-1.4-0.2
Patch foraging time to switch 0 sec0.30.64.1-0.5-0.70.70.7-0.4-0.5-0.60.6-0.20.30.10.1-0.1-0.00.0-0.0-0.50.50.6-1.31.31.5-2.0
Patch foraging water rate 0 sec0.20.31.00.60.5-0.5-0.50.20.70.5-0.50.2-0.60.50.5-0.5-0.50.5-0.50.8-1.00.00.70.3-1.00.1
Patch foraging water rate 12 sec0.40.81.10.80.7-0.7-0.71.00.91.0-1.01.1-0.81.00.8-0.9-0.90.9-0.90.9-0.91.0-0.90.80.7-0.3
Patch foraging water rate 18 sec1.11.63.31.51.4-1.4-1.40.91.41.7-1.71.0-1.41.21.2-1.1-1.41.4-1.41.8-1.80.70.10.9-0.5-0.2
Patch foraging water rate 24 sec0.00.10.2-0.3-0.40.40.4-0.3-0.2-0.10.1-0.20.3-0.2-0.20.20.1-0.10.10.1-0.2-0.10.10.2-0.1-0.3
Patch foraging water rate 6 sec1.11.63.21.31.4-1.4-1.41.81.51.5-1.51.8-1.31.21.2-1.3-1.11.1-1.11.3-1.31.4-0.70.50.50.5
Seeking ratio, delayed vs. immediate footshock2.42.95.11.71.6-1.6-1.61.41.82.2-2.21.6-1.71.61.7-1.8-1.91.9-1.92.2-2.21.4-1.11.40.8-0.6
Distance traveled before self-admin0.20.20.80.50.6-0.6-0.60.00.30.1-0.10.2-0.30.50.6-0.6-0.40.4-0.40.3-0.40.3-0.60.90.5-0.9
Distance traveled after self-admin0.40.62.10.60.4-0.4-0.4-0.50.80.4-0.4-0.3-0.80.70.7-0.7-0.60.6-0.61.0-1.3-0.51.10.9-1.5-0.5
Extensor digitorum longus weight0.31.04.20.50.3-0.3-0.30.80.60.7-0.70.9-0.61.01.0-1.0-0.90.9-0.90.8-0.71.3-2.01.42.0-1.4
Bone: elastic displacement0.00.00.1-0.0-0.10.10.1-0.0-0.10.2-0.2-0.10.1-0.1-0.10.30.2-0.20.20.00.0-0.2-0.1-0.30.20.3
Bone: elastic work2.12.85.0-1.9-2.02.02.0-2.2-1.8-1.71.7-2.21.8-1.7-1.81.81.7-1.71.7-1.51.4-1.71.0-0.4-0.7-0.6
Bone: endosteal estimation0.40.91.8-1.0-1.11.11.1-1.3-1.2-0.80.8-1.31.0-0.9-1.10.90.9-0.90.9-1.01.0-0.9-0.2-0.00.4-0.9
Bone: endosteal perimeter1.22.53.7-1.9-1.91.91.9-1.8-1.8-1.51.5-1.81.7-1.7-1.81.71.7-1.71.7-1.61.6-1.3-0.2-0.60.7-0.5
Epididymis fat weight2.79.213.1-3.6-3.53.53.5-2.9-3.6-3.53.5-3.03.5-3.2-3.13.33.1-3.13.1-3.63.5-2.2-0.3-1.71.2-0.2
Delta time in closed arm before/after self-admin0.60.53.4-0.10.2-0.2-0.2-0.5-0.3-0.60.6-0.60.3-0.6-0.40.80.4-0.40.4-0.50.4-0.91.7-0.9-1.80.9
Delta time in open arm before/after self-admin0.50.52.60.2-0.20.20.20.60.40.8-0.80.5-0.50.70.8-0.8-0.70.7-0.70.5-0.30.6-1.60.51.6-0.4
Diff in mean of infusions in LGA sessions0.40.52.00.00.5-0.5-0.5-0.7-0.2-0.20.2-0.80.2-0.8-0.70.70.6-0.60.6-0.1-0.1-1.11.4-0.9-1.41.0
Delay discount exponential model param0.50.51.1-0.9-1.01.01.0-0.3-0.8-0.90.9-0.20.9-0.4-0.40.40.7-0.70.7-0.80.70.4-0.10.40.3-1.0
Extinction: sum of active levers before priming1.11.22.4-1.1-1.01.01.0-1.5-1.1-1.21.2-1.51.0-1.1-1.01.11.1-1.11.1-1.11.0-1.41.0-0.7-0.8-0.0
Active lever presses in extinction session 60.20.20.5-0.6-0.60.60.6-0.7-0.6-0.50.5-0.60.5-0.5-0.20.40.3-0.30.3-0.40.4-0.3-0.40.10.5-0.6
Bone: final force1.42.25.2-1.4-1.41.41.4-2.3-1.4-1.21.2-2.21.3-1.7-1.71.61.5-1.51.5-0.90.7-2.11.6-0.7-1.5-0.1
Bone: final moment1.52.45.7-1.5-1.51.51.5-2.4-1.4-1.21.2-2.31.4-1.7-1.81.71.6-1.61.6-0.90.6-2.21.7-0.8-1.50.0
Food consumed during 24 hour testing period1.52.13.9-1.4-1.41.41.4-2.0-1.4-1.31.3-1.91.3-1.5-1.51.51.5-1.51.5-1.10.9-1.81.8-0.9-1.70.1
Glucose0.30.42.5-0.0-0.20.20.2-0.2-0.00.0-0.00.1-0.00.40.5-0.4-0.40.4-0.40.3-0.40.6-1.51.21.6-1.6
Heart weight4.87.511.5-3.2-3.43.43.4-3.4-2.9-3.03.0-3.22.9-2.8-2.82.72.9-2.92.9-2.52.2-2.61.6-0.8-1.1-0.6
Delay discount hyperbolic model param0.40.41.0-0.8-0.90.90.9-0.3-0.7-0.80.8-0.10.8-0.4-0.40.40.6-0.60.6-0.70.60.50.00.40.1-1.0
Intermittent access intake day 1-15 change0.10.30.90.30.3-0.3-0.30.70.50.0-0.00.8-0.40.50.7-0.4-0.40.4-0.40.2-0.31.0-0.60.80.6-0.5
Intermittent access intake escalation0.20.41.10.60.6-0.6-0.61.00.70.3-0.31.0-0.70.70.9-0.6-0.60.6-0.60.4-0.41.0-0.70.70.7-0.3
Intermittent access intake escalation 20.40.51.60.40.4-0.4-0.40.80.50.2-0.20.9-0.50.60.8-0.6-0.70.7-0.70.3-0.21.2-1.21.01.3-0.9
Intermitt. access day 1 inactive lever presses0.20.61.5-0.9-1.21.21.2-1.2-0.6-0.80.8-1.00.6-0.5-0.70.50.6-0.60.6-0.2-0.0-0.70.60.5-0.6-0.9
Intermitt. access day 15 inactive lever presses0.10.21.20.40.2-0.2-0.2-0.30.50.5-0.5-0.1-0.40.50.1-0.40.1-0.10.10.9-1.1-0.20.50.7-0.6-0.3
Intermitt. access escalation Index0.50.71.41.01.2-1.2-1.20.70.90.8-0.80.8-0.70.50.7-0.6-0.90.9-0.91.0-1.10.50.20.3-0.40.3
Intermittent access day 1 total infusions0.40.62.3-0.4-0.20.20.2-1.3-0.6-0.50.5-1.30.6-0.8-0.70.70.8-0.80.8-0.40.3-1.51.3-0.6-1.30.4
Intermittent access day 15 total infusions0.10.10.40.50.6-0.6-0.60.30.50.2-0.20.3-0.50.40.6-0.5-0.30.3-0.30.3-0.30.1-0.30.20.20.1
Intermittent access terminal intake (last 3 days)0.00.00.10.10.3-0.3-0.30.10.0-0.10.10.0-0.1-0.00.1-0.00.1-0.10.1-0.20.2-0.0-0.2-0.00.2-0.0
Intermittent access total infusions0.20.20.9-0.2-0.10.10.1-0.9-0.4-0.40.4-0.90.3-0.5-0.40.40.5-0.50.5-0.30.2-1.00.5-0.2-0.4-0.0
Intermittent access day 1 locomotion0.20.20.9-0.3-0.50.50.5-1.0-0.3-0.30.3-0.80.2-0.00.0-0.20.3-0.30.30.0-0.2-0.60.70.6-0.8-0.9
Intermittent access day 15 total locomotion0.20.41.1-0.6-0.70.70.7-1.1-0.6-0.60.6-1.00.5-0.4-0.50.40.8-0.80.8-0.40.3-0.80.50.1-0.5-0.6
Intermittent access total locomotion0.50.61.8-0.7-0.80.80.8-1.3-0.8-0.80.8-1.30.6-0.6-0.60.50.9-0.90.9-0.60.5-1.00.70.1-0.7-0.7
Intermittent access standard deviation0.71.43.4-1.4-1.41.41.4-1.4-1.3-1.81.8-1.21.1-1.0-0.80.90.8-0.80.8-1.41.2-0.40.20.80.0-1.8
Left kidney weight8.539.551.9-7.0-6.86.86.8-6.8-6.7-6.36.3-6.96.8-6.9-7.16.97.2-7.27.2-6.15.8-6.23.8-4.6-2.51.6
Right kidney weight10.548.061.1-7.8-7.77.77.7-7.6-7.5-7.17.1-7.67.5-7.6-7.77.67.8-7.87.8-6.86.3-6.74.2-4.6-2.71.2
Cocaine induced anxiety1.62.23.7-1.5-1.21.21.2-1.9-1.7-1.31.3-1.91.6-1.9-1.81.91.7-1.71.7-1.31.2-1.61.2-1.2-1.00.2
Post-drug Anxiety0.10.10.4-0.20.0-0.0-0.0-0.2-0.3-0.30.3-0.20.4-0.5-0.60.50.4-0.40.4-0.30.3-0.30.5-0.6-0.50.5
Baseline Anxiety2.73.25.21.91.8-1.8-1.82.32.11.8-1.82.2-2.02.11.9-2.1-1.91.9-1.91.6-1.41.6-1.40.71.10.5
Tail length0.41.52.41.31.4-1.4-1.41.51.30.8-0.81.5-1.31.31.4-1.2-1.51.5-1.50.8-0.81.4-0.81.00.5-0.4
Length with tail0.20.91.5-0.9-0.70.70.7-0.8-1.0-0.80.8-0.91.0-1.2-1.11.21.1-1.11.1-1.01.0-0.90.8-1.0-0.60.7
Length without tail2.27.29.7-2.9-2.82.82.8-3.0-2.9-2.52.5-3.02.8-3.1-2.92.93.1-3.13.1-2.62.4-2.72.1-1.9-1.50.4
Times rat made contact with spout0.60.72.6-0.3-0.20.20.2-0.7-0.3-0.10.1-0.80.4-0.8-0.70.80.9-0.90.9-0.20.1-1.31.6-1.2-1.61.4
Lifetime Intake0.70.82.7-0.5-0.40.40.4-1.6-0.7-0.60.6-1.50.6-0.9-0.80.81.0-1.01.0-0.40.2-1.71.3-0.5-1.20.2
Liver weight, left0.81.23.1-1.1-0.90.90.9-0.3-1.3-0.70.7-0.51.4-1.2-1.11.21.1-1.11.1-1.51.8-0.5-0.8-1.71.31.2
Liver weight, right2.13.67.6-2.3-2.12.12.1-0.7-2.4-1.91.9-0.92.5-2.0-2.02.11.8-1.81.8-2.52.8-0.3-1.3-1.62.00.5
Locomotor activity2.03.14.4-2.0-2.02.02.0-1.6-1.8-2.02.0-1.71.9-1.8-2.11.92.0-2.02.0-2.01.9-1.30.8-1.0-0.30.1
Locomotor testing distance0.00.00.10.10.1-0.1-0.10.30.3-0.10.10.3-0.20.20.1-0.1-0.20.2-0.2-0.0-0.00.3-0.00.20.0-0.0
Locomotor testing rearing1.01.92.9-1.6-1.51.51.5-1.3-1.6-1.71.7-1.31.6-1.4-1.61.51.4-1.41.4-1.71.7-1.00.5-1.0-0.20.2
Locomotion in novel chamber1.11.43.60.80.1-0.1-0.11.91.21.0-1.01.9-1.01.81.6-1.8-1.21.2-1.20.9-0.71.8-1.11.01.0-0.1
Locomotion in novel chamber post-restriction0.40.61.40.80.8-0.8-0.81.20.80.7-0.71.2-0.80.91.0-0.9-0.80.8-0.80.6-0.41.2-0.40.60.2-0.3
Fecal boli incidents, locomotor time 10.10.20.40.60.5-0.5-0.5-0.20.50.5-0.5-0.2-0.60.30.5-0.4-0.30.3-0.30.6-0.6-0.30.30.3-0.4-0.1
Change in fecal boli incidents, locomotor task1.00.96.3-0.5-0.10.10.1-0.0-0.3-0.30.3-0.30.5-1.1-1.31.01.0-1.01.0-0.60.6-1.10.9-2.1-0.82.5
Time >=10cm from walls, locomotor time 10.30.40.9-0.6-0.60.60.6-0.9-0.7-0.60.6-0.90.6-0.7-0.60.50.5-0.50.5-0.50.5-0.70.3-0.2-0.2-0.3
Bouts of movement, locomotor time 10.91.01.9-0.9-0.70.70.7-1.0-1.3-0.70.7-1.11.1-1.2-1.01.41.0-1.01.0-1.21.3-1.10.4-1.3-0.10.7
Total resting periods, locomotor time 10.60.61.2-0.7-0.50.50.5-1.0-1.0-0.50.5-1.00.8-0.9-0.81.10.9-0.90.9-0.80.8-1.00.6-0.9-0.40.4
Rest time, locomotor task time 10.91.12.0-1.1-1.11.11.1-1.3-0.9-0.90.9-1.20.9-1.0-1.41.11.2-1.21.2-0.80.7-1.21.1-0.6-1.00.2
Distance moved, locomotor task time 10.20.30.8-0.5-0.60.60.60.0-0.6-0.80.80.00.6-0.1-0.20.30.0-0.00.0-0.90.90.3-0.6-0.10.7-0.2
Vertical activity count, locomotor time 10.00.10.50.1-0.00.00.00.10.0-0.20.20.2-0.00.30.4-0.1-0.40.4-0.4-0.00.00.4-0.70.50.7-0.6
Time >=10cm from walls, locomotor time 20.10.10.50.30.3-0.3-0.3-0.00.40.4-0.40.1-0.30.20.3-0.3-0.50.5-0.50.6-0.70.10.30.4-0.4-0.3
Bouts of movement, locomotor time 20.20.30.6-0.4-0.70.70.7-0.5-0.6-0.00.0-0.50.7-0.3-0.30.30.7-0.70.7-0.10.1-0.40.7-0.4-0.60.2
Total resting periods, locomotor time 20.20.31.0-0.3-0.50.50.5-0.6-0.4-0.00.0-0.60.5-0.3-0.30.30.7-0.70.7-0.0-0.0-0.61.0-0.4-1.00.3
Rest time, locomotor task time 20.10.10.60.30.4-0.4-0.40.10.40.2-0.2-0.0-0.40.0-0.0-0.10.2-0.20.20.3-0.3-0.40.6-0.4-0.60.8
Distance moved, locomotor task time 20.40.40.9-0.8-0.90.90.9-0.3-0.8-1.01.0-0.30.9-0.4-0.50.50.3-0.30.3-0.91.00.1-0.4-0.00.5-0.4
Vertical activity count, locomotor time 20.10.20.5-0.4-0.60.60.6-0.4-0.4-0.70.7-0.40.40.00.00.20.2-0.20.2-0.60.6-0.10.10.2-0.0-0.6
Light reinforcement 10.00.00.10.20.1-0.1-0.10.00.30.2-0.20.0-0.20.20.3-0.2-0.40.4-0.40.3-0.3-0.10.00.1-0.20.1
Light reinforcement 20.61.01.9-1.3-1.11.11.1-0.5-1.2-1.31.3-0.51.2-1.1-1.01.10.9-0.90.9-1.41.4-0.2-0.1-0.60.4-0.1
Bone: marrow area0.41.02.0-1.1-1.11.11.1-1.4-1.2-0.90.9-1.41.0-1.0-1.10.90.9-0.90.9-1.01.0-1.0-0.1-0.10.4-0.9
Bone: maximum diameter2.95.59.7-2.6-2.72.72.7-3.1-2.4-2.32.3-3.02.4-2.5-2.62.62.5-2.52.5-2.01.8-2.71.3-1.1-0.8-0.1
Bone: maximum force2.13.78.1-1.8-1.81.81.8-2.8-1.8-1.71.7-2.81.6-2.0-2.12.01.9-1.91.9-1.31.0-2.62.3-0.9-2.2-0.0
Bone: maximum moment2.34.08.8-1.9-1.91.91.9-3.0-1.8-1.71.7-2.91.7-2.1-2.22.12.0-2.02.0-1.31.0-2.82.4-1.0-2.10.0
Mean time between licks in bursts0.30.71.30.70.6-0.6-0.60.90.70.5-0.51.0-0.71.00.9-0.9-0.90.9-0.90.6-0.61.1-1.01.00.9-0.8
Mean num. licks in bursts1.52.33.2-1.7-1.61.61.6-1.5-1.7-1.41.4-1.61.7-1.7-1.81.81.8-1.81.8-1.51.5-1.40.8-1.2-0.40.4
Cd content in liver1.11.24.8-0.6-0.40.40.4-0.7-0.6-0.30.3-0.90.8-1.2-1.21.21.1-1.11.1-0.50.5-1.61.6-2.0-1.52.2
Co content in liver0.50.54.60.40.4-0.4-0.4-0.40.40.5-0.5-0.4-0.40.0-0.10.00.1-0.10.10.8-1.0-0.81.9-0.2-2.10.7
Cu content in liver6.37.49.83.02.8-2.8-2.82.43.02.9-2.92.5-3.03.03.0-3.1-3.13.1-3.13.1-3.12.3-1.12.50.5-1.2
Fe content in liver0.80.92.3-1.1-1.21.21.2-1.5-0.9-1.31.3-1.30.8-0.6-0.70.50.8-0.80.8-0.80.6-0.70.10.70.0-1.5
K content in liver1.41.31.81.31.3-1.3-1.31.31.31.2-1.21.3-1.31.21.3-1.2-1.21.2-1.21.2-1.21.0-0.30.7-0.00.0
Mg content in liver1.11.22.11.21.2-1.2-1.20.81.31.2-1.20.9-1.21.11.1-1.1-1.21.2-1.21.4-1.40.8-0.01.0-0.3-0.3
Mn content in liver0.10.10.70.30.4-0.4-0.40.60.20.3-0.30.4-0.10.10.1-0.2-0.10.1-0.10.10.10.2-0.4-0.60.40.8
Na content in liver2.02.13.21.51.3-1.3-1.31.31.51.2-1.21.4-1.51.71.8-1.7-1.71.7-1.71.4-1.41.5-1.21.70.9-1.2
Rb content in liver0.40.53.80.20.2-0.2-0.2-0.70.10.4-0.4-0.7-0.1-0.2-0.20.20.3-0.30.30.5-0.6-1.11.8-0.5-2.00.7
Se content in liver0.40.51.20.70.7-0.7-0.71.10.70.5-0.51.1-0.60.80.8-0.8-0.70.7-0.70.4-0.31.0-1.10.31.00.1
Sr content in liver2.42.03.11.51.5-1.5-1.51.71.51.2-1.21.8-1.41.61.6-1.5-1.71.7-1.71.3-1.21.6-1.11.00.8-0.3
Zn content in liver0.20.30.80.60.6-0.6-0.60.40.40.9-0.90.3-0.40.20.2-0.3-0.30.3-0.30.7-0.7-0.00.2-0.3-0.40.7
Bone: minimum diameter0.40.71.4-0.9-1.01.01.0-1.2-0.9-0.80.8-1.20.8-0.7-0.80.70.8-0.80.8-0.80.8-0.90.4-0.1-0.3-0.6
Time in familiar zone, hab. session 10.30.31.70.20.3-0.3-0.3-0.40.10.5-0.5-0.5-0.1-0.4-0.30.50.3-0.30.30.3-0.3-1.10.8-1.0-0.81.3
Time in novel zone, hab. session 11.01.02.8-1.1-1.31.31.3-0.4-1.0-1.51.5-0.31.0-0.3-0.30.30.5-0.50.5-1.21.20.6-0.80.91.1-1.7
Total zone transitions, hab. session 14.56.311.43.13.1-3.1-3.13.02.83.4-3.42.7-2.72.52.5-2.4-2.22.2-2.22.8-2.41.7-0.70.20.21.6
Total locomotion distance, hab. session 12.43.46.42.22.2-2.2-2.22.52.02.3-2.32.3-1.92.01.9-1.8-1.71.7-1.71.7-1.31.6-0.80.20.41.0
Locomotion velocity, hab. session 12.84.06.42.42.4-2.4-2.42.52.22.5-2.52.3-2.22.12.1-2.0-1.91.9-1.92.0-1.71.6-0.60.50.20.8
Time in familiar zone, hab. session 20.30.32.7-0.1-0.10.10.10.6-0.20.2-0.20.50.30.10.2-0.2-0.00.0-0.0-0.30.50.7-1.4-0.11.7-0.0
Time in novel zone, hab. session 20.20.22.0-0.00.0-0.0-0.0-0.60.1-0.40.4-0.6-0.1-0.1-0.10.20.0-0.00.00.0-0.2-0.71.20.0-1.4-0.0
Total zone transitions, hab. session 22.22.85.12.12.1-2.1-2.11.02.02.3-2.30.9-1.91.61.6-1.6-1.31.3-1.32.2-2.20.11.20.3-1.80.9
Total locomotion distance, hab. session 21.41.82.91.71.5-1.5-1.50.91.61.5-1.50.9-1.61.61.5-1.5-1.21.2-1.21.6-1.60.51.20.9-1.7-0.0
Locomotion velocity, hab. session 22.22.94.42.12.0-2.0-2.01.22.01.9-1.91.2-2.02.01.9-1.9-1.61.6-1.62.0-2.00.81.11.1-1.7-0.1
Novel to familiar place preference ratio2.22.43.6-1.8-1.71.71.7-1.3-1.7-1.71.7-1.41.8-1.9-1.81.81.7-1.71.7-1.81.7-1.10.5-1.3-0.10.5
Novelty place preference3.13.34.8-2.1-1.91.91.9-1.5-2.0-1.91.9-1.62.1-2.2-2.12.22.0-2.02.0-2.12.1-1.30.5-1.7-0.00.8
Time in novel zone, NPP test3.84.15.9-2.3-2.12.12.1-1.7-2.2-2.12.1-1.82.3-2.4-2.32.42.2-2.22.2-2.32.2-1.60.7-1.8-0.20.9
Total zone transitions, NPP test4.46.410.83.23.2-3.2-3.22.62.93.3-3.32.4-2.82.62.6-2.4-2.22.2-2.22.9-2.71.30.40.3-1.11.6
Total locomotion distance, NPP test2.23.04.62.12.1-2.1-2.11.72.02.0-2.01.6-2.01.91.8-1.7-1.51.5-1.51.9-1.80.91.30.4-1.90.8
Locomotion velocity, NPP test2.84.06.02.42.4-2.4-2.42.12.32.3-2.32.0-2.32.32.2-2.1-1.91.9-1.92.2-2.01.40.90.8-1.50.5
Intraocular pressure0.40.51.5-0.6-0.40.40.4-0.4-0.7-0.90.9-0.60.7-0.7-0.50.80.6-0.60.6-1.11.1-0.80.5-1.2-0.41.0
Delta distance traveled before/after self-admin0.60.64.1-0.2-0.30.30.3-0.8-0.1-0.10.1-0.90.1-0.3-0.30.50.5-0.50.50.1-0.2-1.31.9-0.8-2.01.0
Delta ambulatory time before/after self-admin0.60.85.2-0.1-0.10.10.1-0.9-0.1-0.00.0-1.00.2-0.5-0.50.60.5-0.50.50.2-0.3-1.52.1-0.9-2.31.1
Parametrial fat weight0.10.31.3-0.4-0.20.20.20.4-0.5-0.60.60.30.4-0.3-0.20.20.1-0.10.1-0.91.00.5-1.0-0.31.10.0
Pavlov. Cond. lever latency0.40.50.9-0.7-0.70.70.7-0.7-0.8-0.50.5-0.70.8-0.8-0.80.81.0-1.01.0-0.70.8-0.70.5-0.7-0.30.4
Pavlov. Cond. magazine entry latency0.40.50.90.90.9-0.9-0.90.50.90.8-0.80.5-0.90.70.8-0.6-0.80.8-0.80.9-1.00.20.30.3-0.50.2
Pavlov. Cond. change in total contacts1.41.43.31.51.4-1.4-1.40.51.51.3-1.30.6-1.51.21.2-1.1-1.31.3-1.31.7-1.80.10.50.6-0.90.2
Pavlov. Cond. index score0.20.30.70.60.6-0.6-0.60.20.70.5-0.50.2-0.70.50.5-0.4-0.60.6-0.60.7-0.8-0.00.30.2-0.50.1
Pavlov. Cond. latency score0.20.20.50.50.5-0.5-0.50.30.60.4-0.40.3-0.60.50.5-0.4-0.60.6-0.60.6-0.70.20.10.4-0.2-0.1
Pavlov. Cond. lever contacts1.31.52.41.31.3-1.3-1.31.11.31.1-1.11.2-1.41.41.4-1.4-1.51.5-1.51.3-1.31.1-0.91.10.6-0.6
Pavlov. Cond. magazine entry number0.50.61.0-1.0-1.01.01.0-0.6-1.0-0.80.8-0.51.0-0.7-0.70.60.7-0.70.7-0.91.0-0.1-0.7-0.01.0-0.5
Pavlov. Cond. intertrial magazine entries0.91.12.11.21.1-1.1-1.10.71.31.2-1.20.7-1.31.11.1-1.1-1.21.2-1.21.4-1.50.5-0.30.90.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.80.8-0.8-0.80.40.80.7-0.70.4-0.80.60.6-0.5-0.70.7-0.70.9-0.90.10.20.1-0.40.3
Pavlov. Cond. response bias0.60.81.31.11.1-1.1-1.10.61.10.9-0.90.7-1.10.90.9-0.8-1.01.0-1.01.1-1.10.40.40.4-0.70.1
Pavlov. Cond. lever latency0.81.12.7-0.9-0.70.70.7-0.6-1.1-0.90.9-0.81.1-1.2-1.11.11.1-1.11.1-1.31.5-1.00.9-1.6-0.71.3
Pavlov. Cond. magazine entry latency2.12.65.11.81.7-1.7-1.70.91.91.6-1.61.1-2.01.81.7-1.8-1.71.7-1.72.1-2.30.90.11.8-0.5-1.0
Pavlov. Cond. change in total contacts0.40.63.00.60.4-0.4-0.4-0.60.80.6-0.6-0.3-0.90.50.5-0.5-0.60.6-0.61.4-1.7-0.30.61.3-0.8-1.1
Pavlov. Cond. index score1.41.84.21.41.3-1.3-1.30.81.61.4-1.41.0-1.61.51.4-1.4-1.41.4-1.41.9-2.00.9-0.31.7-0.0-1.0
Pavlov. Cond. latency score1.92.55.51.71.6-1.6-1.61.01.91.7-1.71.2-1.91.71.6-1.7-1.71.7-1.72.2-2.31.0-0.21.7-0.2-0.9
Pavlov. Cond. lever contacts1.11.53.11.10.9-0.9-0.90.81.31.1-1.11.0-1.31.31.3-1.3-1.31.3-1.31.5-1.71.2-0.91.80.7-1.3
Pavlov. Cond. magazine entry number1.21.43.2-1.4-1.31.31.3-0.7-1.5-1.31.3-0.81.5-1.3-1.21.21.2-1.21.2-1.71.8-0.6-0.2-1.20.60.5
Pavlov. Cond. intertrial magazine entries1.62.43.1-1.6-1.51.51.5-1.7-1.5-1.41.4-1.71.6-1.7-1.61.71.7-1.71.7-1.41.3-1.81.7-1.4-1.50.9
Pavlov. Cond. lever-magazine prob. diff.1.52.04.21.41.3-1.3-1.30.81.61.4-1.41.0-1.61.51.5-1.5-1.51.5-1.51.9-2.01.1-0.41.80.1-1.2
Pavlov. Cond. response bias0.91.23.11.10.9-0.9-0.90.41.31.1-1.10.7-1.31.21.2-1.2-1.21.2-1.21.6-1.80.7-0.51.60.3-1.1
Time in closed arm before self-admin4.35.511.52.22.0-2.0-2.01.52.11.5-1.51.9-2.32.62.4-2.8-2.92.9-2.92.0-2.02.4-2.43.41.9-3.0
Time in closed arm after self-admin0.10.10.7-0.00.2-0.2-0.2-0.4-0.2-0.60.6-0.30.0-0.1-0.10.1-0.20.2-0.2-0.40.4-0.10.10.4-0.2-0.8
Time in open arm before self-admin0.20.21.2-0.10.1-0.1-0.10.4-0.2-0.20.20.30.3-0.3-0.20.40.3-0.30.3-0.50.70.10.5-1.0-0.51.1
Time in open arm after self-admin0.20.31.20.1-0.20.20.20.90.30.5-0.50.7-0.30.40.5-0.5-0.30.3-0.30.10.10.7-1.0-0.11.10.4
Bone: periosteal estimation0.92.04.1-1.6-1.71.71.7-2.0-1.6-1.31.3-2.01.4-1.4-1.51.41.4-1.41.4-1.21.1-1.50.5-0.3-0.2-0.8
Bone: periosteal perimeter2.95.07.2-2.6-2.72.72.7-2.6-2.5-2.22.2-2.62.4-2.5-2.52.52.4-2.42.4-2.22.2-2.10.3-1.00.3-0.3
Bone: post-yield work0.50.74.6-0.2-0.10.10.1-1.1-0.1-0.30.3-1.10.1-0.6-0.60.60.6-0.60.60.1-0.3-1.52.0-0.6-2.10.7
Progressive ratio test 1 active lever presses0.30.41.7-0.10.3-0.3-0.3-1.0-0.4-0.40.4-1.10.3-0.7-0.60.60.5-0.50.5-0.30.2-1.31.1-0.6-1.20.5
Progressive ratio test 1 breakpoint0.30.41.50.00.4-0.4-0.4-0.9-0.3-0.30.3-0.90.2-0.6-0.50.60.4-0.40.4-0.20.2-1.21.1-0.7-1.20.6
Progressive ratio test 1 inactive lever presses0.30.41.5-0.4-0.70.70.7-1.2-0.4-0.20.2-1.00.3-0.2-0.30.20.4-0.40.40.1-0.3-0.90.90.6-1.0-0.8
Progressive ratio test 2 active lever presses0.40.42.20.30.5-0.5-0.5-0.7-0.00.1-0.1-0.8-0.0-0.4-0.20.30.4-0.40.40.2-0.2-1.31.4-0.8-1.50.9
Progressive ratio test 2 breakpoint0.40.42.10.30.6-0.6-0.6-0.70.00.1-0.1-0.7-0.1-0.3-0.10.30.4-0.40.40.2-0.2-1.21.3-0.8-1.40.9
Progressive ratio test 2 inactive lever presses0.30.51.01.01.0-1.0-1.00.40.70.7-0.70.4-0.80.90.9-0.8-0.60.6-0.60.7-0.60.30.20.5-0.4-0.2
Incentive Sensitization - Responses0.30.41.10.70.8-0.8-0.80.40.60.8-0.80.3-0.50.30.4-0.3-0.20.2-0.20.7-0.6-0.10.8-0.4-1.00.9
Incentive Sensitization - Breakpoint0.20.31.30.50.6-0.6-0.60.20.40.7-0.70.1-0.30.10.3-0.1-0.00.0-0.00.6-0.5-0.31.0-0.5-1.10.9
Sum of active levers in priming session hrs 5-60.10.10.2-0.2-0.20.20.2-0.2-0.3-0.30.3-0.20.3-0.2-0.10.20.1-0.10.1-0.20.20.0-0.20.10.3-0.4
Progressive ratio0.20.21.90.0-0.10.10.1-0.1-0.00.0-0.00.0-0.10.30.3-0.2-0.20.2-0.20.1-0.10.3-1.20.81.4-1.0
Food seeking constrained by brief footshock1.11.42.6-1.2-1.11.11.1-1.4-1.1-0.70.7-1.41.1-1.6-1.51.51.3-1.31.3-0.80.7-1.61.0-1.2-0.80.9
Seeking ratio, punishment vs. effort0.81.14.5-0.8-0.60.60.6-0.9-0.6-0.60.6-1.00.7-1.2-1.11.11.0-1.01.0-0.60.5-1.32.0-1.1-2.11.1
Retroperitoneal fat weight4.418.926.5-5.1-4.84.84.8-4.2-4.9-4.74.7-4.34.9-5.1-4.85.14.7-4.74.7-4.84.7-3.51.7-3.2-0.60.8
Reaction time number correct0.71.42.91.31.5-1.5-1.51.71.11.4-1.41.6-1.01.00.9-1.0-1.21.2-1.21.0-0.81.2-1.1-0.11.00.8
Reaction time mean minus median0.10.31.9-0.5-0.60.60.6-0.2-0.6-0.50.5-0.20.5-0.1-0.10.10.1-0.10.1-0.60.60.3-1.20.41.4-0.9
Reaction time mean minus median AUC0.51.22.4-1.3-1.41.41.4-0.7-1.4-1.41.4-0.71.3-0.8-0.80.80.9-0.90.9-1.51.6-0.1-1.0-0.11.4-0.8
Reaction time num false alarms0.20.31.10.20.0-0.0-0.00.40.10.1-0.10.5-0.20.50.6-0.4-0.50.5-0.50.10.00.8-1.00.71.0-0.8
Reaction time num false alarms AUC0.30.41.20.40.4-0.4-0.40.80.40.4-0.40.8-0.40.70.8-0.6-0.80.8-0.80.2-0.10.9-1.10.51.1-0.4
Reaction time trials correct on left0.71.42.91.31.5-1.5-1.51.71.11.4-1.41.6-1.01.00.9-1.0-1.21.2-1.21.0-0.81.2-1.1-0.11.00.8
Reaction time trials on left0.81.63.21.41.5-1.5-1.51.81.21.5-1.51.6-1.11.11.0-1.0-1.31.3-1.31.0-0.81.2-1.2-0.11.00.8
Reaction time mean0.20.31.40.1-0.00.00.00.30.1-0.50.50.4-0.10.50.5-0.4-0.60.6-0.6-0.20.20.8-0.91.00.9-1.2
Reaction time mean AUC0.10.20.70.10.0-0.0-0.00.30.1-0.50.50.4-0.10.40.4-0.4-0.50.5-0.5-0.30.30.6-0.70.70.6-0.8
Median of all reaction times0.20.31.10.30.3-0.3-0.30.40.3-0.30.30.6-0.30.60.7-0.6-0.80.8-0.8-0.1-0.00.9-0.61.00.5-1.0
Reaction time omissions0.30.51.00.70.7-0.7-0.70.80.50.7-0.70.8-0.50.80.7-0.7-0.80.8-0.80.4-0.20.6-1.00.20.90.1
Reaction time false alarm rate0.10.20.7-0.4-0.50.50.5-0.1-0.3-0.40.4-0.10.30.10.20.0-0.10.1-0.1-0.30.30.3-0.60.50.6-0.9
Reaction time premature initiation rate0.30.42.10.40.4-0.4-0.4-0.50.6-0.10.1-0.2-0.70.30.4-0.3-0.30.3-0.30.6-0.9-0.21.21.0-1.4-1.0
Reaction time premature initiations0.20.41.00.70.8-0.8-0.80.20.80.3-0.30.3-0.80.40.5-0.5-0.60.6-0.60.7-0.90.10.80.6-1.0-0.3
Std. dev. reaction times0.20.51.5-0.7-0.80.80.8-0.3-0.7-0.90.9-0.30.7-0.2-0.30.20.2-0.20.2-0.90.90.1-1.00.31.2-0.8
Reaction time trials completed0.81.63.21.41.5-1.5-1.51.81.21.5-1.51.6-1.11.11.0-1.0-1.31.3-1.31.0-0.81.2-1.2-0.11.00.8
Reaction time trials AUC0.61.12.31.11.3-1.3-1.31.50.91.2-1.21.4-0.90.80.8-0.8-1.11.1-1.10.8-0.61.0-1.0-0.10.90.7
Run reversals in cocaine runway, females0.60.61.20.91.0-1.0-1.00.90.71.1-1.10.8-0.60.50.9-0.6-0.90.9-0.90.9-0.80.6-0.50.10.30.3
Run reversals in cocaine runway, males0.80.84.1-0.30.1-0.1-0.1-0.6-0.9-0.50.5-0.90.9-0.9-0.90.80.8-0.80.8-1.01.3-1.30.5-2.0-0.31.8
Latency to leave start box in cocaine runway0.50.61.2-1.0-1.01.01.0-0.4-0.9-1.11.1-0.40.8-0.7-0.60.80.5-0.50.5-1.11.1-0.0-0.1-0.20.3-0.3
Latency to leave start box in cocaine runway, F0.00.00.1-0.0-0.00.00.00.20.10.0-0.00.2-0.10.10.1-0.1-0.10.1-0.1-0.00.00.4-0.10.20.1-0.3
Latency to leave start box in cocaine runway, M1.61.53.1-1.6-1.61.61.6-0.8-1.4-1.81.8-0.81.3-1.2-1.11.21.0-1.01.0-1.71.7-0.4-0.0-0.60.4-0.2
Std. dev. time between licks in bursts1.41.93.71.61.4-1.4-1.40.81.61.4-1.40.9-1.61.61.6-1.5-1.61.6-1.61.8-1.90.70.11.3-0.6-0.6
Total sessions with >9 infusions3.94.79.5-1.9-1.81.81.8-2.9-1.9-1.91.9-2.82.0-2.3-2.22.32.3-2.32.3-1.41.0-2.93.1-1.5-2.90.8
Short access day 1 total inactive lever presses1.01.36.6-0.6-1.11.11.1-2.0-0.3-0.20.2-1.80.3-0.6-0.60.50.7-0.70.70.4-0.8-1.82.40.3-2.6-0.4
Short access day 10 total inactive lever presses0.40.92.0-1.2-1.41.41.4-0.9-0.9-1.11.1-0.90.9-0.7-0.80.60.9-0.90.9-1.11.1-0.7-0.4-0.30.7-0.2
Short access day 1 total infusions0.70.92.8-0.8-1.01.01.0-1.7-0.7-0.50.5-1.50.8-0.8-0.80.81.0-1.01.0-0.1-0.2-1.51.3-0.1-1.2-0.2
Short access day 10 total infusions1.52.04.0-1.4-1.21.21.2-1.9-1.3-2.02.0-1.81.2-1.4-1.31.31.2-1.21.2-1.41.1-1.61.6-0.4-1.5-0.4
Short access total infusions1.92.46.5-1.2-1.21.21.2-2.5-1.3-1.31.3-2.41.3-1.5-1.41.51.5-1.51.5-0.70.3-2.52.3-0.7-2.30.2
Short access day 1 locomotion0.50.61.2-0.8-0.90.90.9-1.1-0.6-0.80.8-0.90.6-0.6-0.70.50.9-0.90.9-0.30.1-0.50.90.5-0.8-0.9
Short access day 10 total locomotion0.30.64.0-0.4-0.90.90.9-0.3-0.0-0.90.9-0.0-0.00.60.5-0.8-0.20.2-0.2-0.30.10.6-0.51.60.4-2.0
Short access total locomotion1.11.32.5-1.3-1.51.51.5-1.6-1.0-1.61.6-1.31.0-0.7-0.70.61.0-1.01.0-0.90.6-0.81.20.5-1.2-1.2
One hour access (0.3 mA shock)0.10.10.40.1-0.00.00.00.00.1-0.30.30.1-0.20.40.6-0.4-0.30.3-0.3-0.10.10.20.20.6-0.3-0.6
Compulsive drug intake1.01.16.01.00.9-0.9-0.90.71.21.1-1.10.5-0.90.50.7-0.5-0.30.3-0.31.1-1.0-0.61.5-1.3-1.92.4
One hour access (shock baseline)0.30.43.5-0.4-0.40.40.4-0.3-0.5-0.70.7-0.20.30.10.1-0.0-0.10.1-0.1-0.60.50.6-0.81.20.9-1.9
Social response proportion0.60.73.3-0.9-1.21.21.2-0.7-0.5-1.31.3-0.40.5-0.2-0.30.00.3-0.30.3-0.60.40.3-0.11.20.2-1.8
Social responses0.10.10.30.50.4-0.4-0.40.30.50.4-0.40.3-0.50.50.4-0.5-0.40.4-0.40.4-0.40.10.10.1-0.20.2
Social time1.62.23.11.61.5-1.5-1.51.41.71.6-1.61.5-1.71.51.5-1.7-1.81.8-1.81.7-1.71.2-0.51.30.1-0.5
Soleus weight0.30.92.71.11.1-1.1-1.10.41.11.6-1.60.3-1.00.50.6-0.5-0.50.5-0.51.6-1.6-0.40.4-0.3-0.61.2
Bone: stiffness1.32.15.1-1.5-1.61.61.6-2.3-1.4-1.61.6-2.11.3-1.3-1.31.31.3-1.31.3-1.00.8-1.81.5-0.1-1.4-0.8
Tibialis anterior weight0.72.23.51.61.4-1.4-1.41.11.51.8-1.81.2-1.61.71.7-1.6-1.61.6-1.61.9-1.91.1-1.31.31.0-0.7
Time to tail flick, vehicle, before self-admin0.00.00.1-0.0-0.00.00.0-0.3-0.0-0.10.1-0.2-0.10.00.0-0.1-0.00.0-0.0-0.0-0.0-0.10.00.3-0.0-0.4
Time to tail flick, vehicle, after self-admin1.11.53.11.31.3-1.3-1.31.11.01.6-1.61.1-1.11.11.1-1.2-1.11.1-1.11.2-1.01.1-1.80.81.7-0.5
Time to tail flick, test, before self-admin0.60.71.6-0.7-0.60.60.6-0.3-0.9-0.70.7-0.50.9-0.8-0.80.91.0-1.01.0-1.11.3-0.60.0-1.20.20.9
Time to tail flick, test, after self-admin0.40.40.80.70.8-0.8-0.80.70.50.4-0.40.6-0.40.70.8-0.7-0.60.6-0.60.3-0.20.6-0.90.30.8-0.0
Delta time to tail flick, vehicle, before/after SA0.00.00.2-0.0-0.00.00.0-0.2-0.00.3-0.3-0.10.0-0.1-0.1-0.00.0-0.00.00.2-0.2-0.0-0.40.30.5-0.4
Delta time to tail flick, test, before/after SA3.13.24.11.91.8-1.8-1.81.61.91.9-1.91.8-1.82.01.9-2.0-2.02.0-2.02.0-2.01.6-1.31.61.0-0.8
Tibia length0.72.04.7-1.1-0.90.90.9-1.7-1.2-0.90.9-1.81.2-1.7-1.81.71.5-1.51.5-0.90.8-2.21.3-1.8-1.11.5
Ambulatory time before self-admin0.30.50.90.80.9-0.9-0.90.50.60.5-0.50.6-0.60.80.9-1.0-0.70.7-0.70.6-0.60.6-0.90.70.8-0.4
Ambulatory time after self-admin1.61.94.11.71.5-1.5-1.50.71.71.5-1.50.8-1.61.61.5-1.6-1.41.4-1.41.9-2.00.30.51.0-1.00.0
Bone: tissue strength0.20.20.6-0.4-0.30.30.3-0.4-0.4-0.50.5-0.40.4-0.6-0.60.50.5-0.50.5-0.40.4-0.50.8-0.5-0.70.5
Total heroin consumption0.40.42.00.00.2-0.2-0.2-0.8-0.3-0.30.3-0.90.3-0.5-0.50.50.5-0.50.5-0.10.0-1.21.3-0.8-1.40.8
Bone: trabecular number0.00.00.1-0.00.0-0.0-0.00.2-0.10.1-0.10.20.1-0.1-0.10.00.0-0.00.0-0.10.10.2-0.2-0.20.30.2
Bone: trabecular spacing1.41.84.1-1.2-1.21.21.2-1.9-1.2-1.31.3-1.91.1-1.4-1.31.41.5-1.51.5-1.10.9-2.01.3-1.1-1.10.6
Bone: trabecular thickness0.40.51.90.30.2-0.2-0.20.60.20.4-0.40.7-0.30.60.6-0.6-0.70.7-0.70.4-0.41.2-1.31.21.3-1.4
Bone: trabecular tissue density1.92.85.31.51.2-1.2-1.21.31.61.4-1.41.5-1.61.81.8-1.9-1.91.9-1.91.8-1.81.8-1.72.31.4-1.9
Water consumed over 24 hours0.30.41.5-0.3-0.20.20.2-0.8-0.3-0.20.2-0.90.3-0.7-0.60.70.7-0.70.7-0.10.1-1.21.2-0.8-1.20.8
Number of responses in last shaping day0.80.94.50.70.6-0.6-0.6-0.40.70.3-0.3-0.1-0.91.11.0-1.0-0.90.9-0.91.1-1.30.3-0.12.1-0.2-2.1