Hub : Genes

Srsf5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb alternative TSS XM_039111859.2 0.22 0.14 9.4e-03 0.02 0.06 0 0.05 1.0e-01 1.8e-02 3.1e-01 2.5e-02
2 Adipose mRNA stability Srsf5 0.03 0.02 5.1e-03 0 0 0 -0 3.4e-01 2.4e-01 1.6e-01 4.4e-01
3 IL isoform ratio XR_010052053.1 0.74 0.12 3.5e-04 0.08 0.18 0.22 0.23 7.1e-03 4.7e-05 5.6e-06 3.8e-06
4 Liver intron excision ratio chr6_106338816_106340047 0.07 0.04 2.4e-05 0.05 0.04 0.03 0.04 3.7e-06 2.6e-05 9.9e-05 2.0e-05
5 Liver alternative TSS NM_001195505.1 0.04 0.02 1.4e-03 0.01 0.01 0.01 0 4.2e-02 8.4e-03 1.8e-02 8.6e-02
6 Liver alternative polyA XM_039111859.2 0.03 0.02 5.8e-03 0.01 0.01 0 0.01 8.2e-03 4.4e-02 2.6e-01 3.6e-02
7 Liver alternative polyA XM_063261591.1 0.03 0.02 2.9e-03 0.01 0.01 0 0.01 6.9e-03 2.0e-02 1.3e-01 2.1e-02
8 Liver alternative TSS XM_039111860.2 0.04 0.02 3.6e-03 0 0.01 0.01 0 7.2e-02 1.7e-02 5.2e-02 1.0e-01
9 Liver isoform ratio NM_001195506.1 0.06 0.04 1.1e-04 0.03 0.02 0.02 0.02 1.7e-04 2.4e-03 3.5e-03 3.5e-03
10 Liver gene expression Srsf5 0.04 0.02 4.3e-04 0.02 0.02 0.02 0.02 1.6e-03 3.3e-03 3.4e-03 5.1e-03
11 NAcc gene expression Srsf5 0.05 0.04 9.4e-03 0 0 -0 -0 1.2e-01 9.2e-02 5.2e-01 5.0e-01
12 Liver isoform ratio NM_001195505.1 0.13 0.07 2.2e-04 0.05 0.03 0.03 0.03 5.1e-06 6.2e-04 6.2e-04 1.6e-04
13 Liver intron excision ratio chr6_106338816_106339079 0.05 0.03 4.6e-04 0.01 0.03 0.03 0.02 2.4e-02 4.2e-04 1.9e-04 3.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.61.03.71.0-1.9-1.2-1.40.3-0.30.3-0.5-0.41.0-1.70.80.2
Area under the delay curve0.20.30.80.7-0.6-0.4-0.60.3-0.20.2-0.4-0.50.1-0.50.90.9
BMI with tail1.34.59.4-1.8-1.33.1-2.82.8-1.51.5-2.7-1.62.3-0.42.80.3
BMI without tail1.15.610.91.9-3.3-1.1-3.22.1-2.42.4-2.4-2.51.9-1.62.92.2
Body weight1.46.118.63.3-4.3-1.8-2.81.6-2.02.0-1.9-2.33.2-0.82.21.9
Weight adjusted by age0.61.76.11.4-2.5-0.1-1.90.70.0-0.0-0.7-0.20.9-2.31.70.5
Bone surface0.61.26.81.0-1.9-0.8-1.3-0.30.4-0.40.20.40.3-2.60.7-0.8
Bone volume0.71.35.91.6-1.8-1.9-0.8-0.70.3-0.30.40.20.1-2.40.3-0.4
Breakpoint value in progressive ratio session0.51.03.70.1-1.90.4-1.80.50.3-0.3-0.50.71.4-1.60.5-0.0
Number of licking bursts0.31.03.6-1.71.71.90.50.5-0.20.2-0.3-0.1-1.30.50.70.2
Context. condit. distance diff. score0.50.61.91.3-0.8-1.4-0.40.2-0.70.7-0.3-0.90.60.80.00.8
Locomotion velocity, session 10.50.51.2-0.70.30.50.2-0.51.1-1.10.61.0-0.1-0.1-1.0-0.9
Locomotion distance, session 10.50.62.1-1.50.61.1-0.81.2-0.30.3-1.1-0.3-0.00.30.50.4
Locomotion velocity, session 20.10.20.6-0.50.4-0.30.8-0.20.4-0.40.0-0.00.20.7-0.30.5
Locomotion distance, session 20.50.74.0-2.01.31.1-0.20.9-0.00.0-0.8-0.0-0.40.6-0.10.2
Locomotion velocity, session 32.02.36.91.21.3-2.62.3-1.90.9-0.91.60.6-1.50.6-1.80.2
Locomotion distance, session 30.70.82.50.70.5-1.21.1-1.20.7-0.71.10.5-1.6-1.0-0.6-0.1
Stereotopy head waving bouts, day 30.40.52.01.4-0.8-1.00.5-0.70.2-0.20.5-0.1-0.3-1.00.50.2
Stereotopy head waving duration, day 30.50.71.71.1-0.3-1.31.1-1.30.6-0.61.00.3-0.4-0.6-0.5-0.2
Locomotion velocity, session 71.92.05.0-0.51.7-0.32.2-1.71.4-1.41.71.0-1.80.1-1.7-1.0
Locomotion distance, session 70.40.51.1-0.80.90.60.20.8-0.90.9-0.7-1.1-0.30.70.30.7
Stereotopy head waving bouts, day 71.01.15.32.3-1.5-2.3-0.3-0.5-0.10.10.20.00.5-1.0-0.00.6
Stereotopy head waving duration, day 71.31.67.32.6-1.9-2.7-0.4-0.5-0.40.40.1-0.31.0-0.9-0.10.8
Locomotion velocity, session 80.20.21.0-0.60.20.1-0.30.4-0.00.0-0.4-0.10.81.0-0.7-0.0
Locomotion distance, session 80.40.61.3-0.20.2-0.4-0.61.1-1.01.0-1.1-1.10.21.00.30.8
Degree of sensitization distance0.91.02.1-0.6-0.00.8-0.81.3-1.11.1-1.2-1.21.11.40.50.7
Degree of sensitization stereotypy0.91.04.72.2-1.4-2.1-0.4-0.3-0.30.30.10.00.8-0.5-0.20.6
Conditioned locomotion2.52.94.9-0.52.0-0.62.2-2.02.0-2.02.01.9-1.90.4-1.9-1.1
Cocaine response after cond. corrected2.23.35.8-1.22.40.12.1-1.92.2-2.22.02.0-2.4-0.3-1.6-1.5
Cocaine response after cond. not corrected1.82.64.5-1.42.10.11.9-1.61.8-1.81.71.8-2.1-0.4-1.6-1.3
Cocaine response before conditioning0.40.51.1-0.3-1.00.2-0.80.7-0.90.9-0.7-0.70.8-0.70.30.3
Saline control response0.10.10.4-0.40.2-0.2-0.10.4-0.40.4-0.5-0.50.30.20.10.7
Bone: connectivity density0.71.12.70.5-1.6-0.0-1.61.0-0.70.7-1.1-0.80.9-1.31.50.3
Bone: cortical apparent density0.20.31.20.5-0.2-1.10.20.0-0.00.0-0.2-0.60.20.60.20.9
Bone: cortical area0.50.82.31.4-0.1-1.51.1-1.30.6-0.61.20.5-0.6-0.6-0.6-0.2
Bone: cortical porosity0.80.92.20.9-1.10.6-1.11.0-1.01.0-1.0-1.01.50.30.80.6
Bone: cortical porosity0.60.71.31.1-1.10.3-1.00.7-0.80.8-0.7-0.91.10.10.70.4
Bone: cortical thickness0.30.51.20.40.8-0.70.70.2-0.80.8-0.2-1.0-0.11.10.10.8
Bone: cortical thickness1.21.57.4-1.82.71.31.00.40.2-0.2-0.10.4-0.82.1-0.9-0.1
Bone: cortical tissue density0.10.21.00.4-0.2-1.00.20.00.0-0.0-0.2-0.50.20.60.20.8
Condit. Reinf. active minus inactive responses1.31.53.01.7-1.4-1.3-1.71.1-0.80.8-1.1-0.81.60.90.41.4
Condit. Reinf. active-inactive response ratio1.11.13.41.8-1.3-1.8-1.30.6-0.60.6-0.7-0.71.10.50.21.0
Condit. Reinf. active responses1.51.93.51.3-1.1-0.4-1.91.6-1.31.3-1.6-1.21.91.70.61.3
Condit. Reinf. inactive responses1.82.34.7-0.9-0.22.2-1.62.1-1.61.6-1.9-1.31.61.61.20.6
Incentive salience index mean0.70.92.21.2-1.2-0.7-1.50.9-0.60.6-0.9-0.51.50.90.00.6
Condit. Reinf. lever presses0.20.30.9-0.1-0.70.6-1.00.5-0.20.2-0.4-0.10.90.4-0.4-0.7
Condit. Reinf. active minus inactive responses2.23.47.5-0.5-0.71.4-2.32.7-1.81.8-2.6-2.02.11.41.71.4
Condit. Reinf. active-inactive response ratio1.42.23.80.4-1.00.3-1.71.9-1.71.7-1.9-1.91.60.71.71.4
Condit. Reinf. active responses0.91.23.1-0.0-0.80.5-1.51.6-1.01.0-1.5-1.21.80.80.70.8
Condit. Reinf. inactive responses0.40.62.1-0.60.40.30.9-0.60.8-0.80.70.80.10.4-1.4-1.1
Condit. Reinf. lever presses0.20.31.40.4-1.20.1-0.8-0.00.2-0.2-0.00.40.9-0.90.0-0.3
Condit. Reinf. lever reinforcers received1.11.64.6-0.1-1.00.7-1.81.8-1.01.0-1.7-1.12.10.90.80.9
Conditioned reinforcement - actives0.10.52.0-0.50.30.4-0.10.8-0.40.4-0.8-0.61.21.4-0.21.1
Conditioned reinforcement - inactives0.30.92.1-1.41.41.30.30.21.3-1.30.11.00.21.1-0.8-0.4
Conditioned locomotion0.40.62.2-1.31.20.60.80.40.2-0.2-0.3-0.10.41.5-0.60.7
Patch foraging indifference point 0 sec0.30.82.50.9-1.60.0-0.80.5-0.50.5-0.6-1.01.1-1.01.30.9
Patch foraging indifference point AUC0.20.51.30.7-0.1-1.20.8-1.00.7-0.70.90.70.00.2-1.10.1
Delay disc. indifference point, 0s delay2.12.34.4-0.4-1.01.2-1.92.1-1.61.6-2.1-1.71.60.42.01.0
Delay disc. indifference point, 16s delay0.71.02.41.30.1-1.50.7-1.21.1-1.11.20.9-1.0-0.4-0.7-0.1
Delay disc. indifference point, 2s delay2.02.24.30.7-1.50.3-2.11.7-1.31.3-1.8-1.71.80.31.61.5
Delay disc. indifference point, 24s delay0.10.10.70.8-0.2-0.3-0.3-0.10.2-0.20.1-0.1-0.3-0.30.50.5
Delay disc. indifference point, 4s delay0.20.21.60.1-0.20.4-0.20.3-0.30.3-0.3-0.5-0.6-0.31.30.7
Delay disc. indifference point, 8s delay0.81.33.11.1-1.5-1.0-1.40.9-0.80.8-1.1-0.90.6-1.01.41.8
Indifference point function ln k0.51.62.70.7-1.10.6-1.61.6-1.41.4-1.5-1.51.1-0.21.60.9
Indifference point function log k0.51.62.70.7-1.10.6-1.61.6-1.41.4-1.5-1.51.1-0.21.60.9
Patch foraging total patch changes 0 sec0.51.33.71.0-1.90.1-1.20.8-0.80.8-0.9-1.31.5-1.01.61.0
Patch foraging total patch changes 12 sec0.60.82.91.7-1.5-1.2-0.1-0.50.1-0.10.2-0.20.5-1.00.81.2
Patch foraging total patch changes 18 sec0.20.41.40.9-1.2-0.60.1-0.50.4-0.40.40.00.3-1.10.70.2
Patch foraging total patch changes 24 sec0.41.47.12.5-1.2-2.70.4-0.6-0.60.60.3-0.60.4-0.10.11.4
Patch foraging total patch changes 6 sec0.10.21.01.0-0.4-0.80.4-0.6-0.20.20.4-0.30.0-0.50.10.4
Patch foraging time to switch 0 sec0.72.55.7-0.41.7-0.92.1-2.01.7-1.71.91.4-2.4-0.4-1.4-1.0
Patch foraging water rate 0 sec1.14.27.51.7-2.30.1-2.72.3-2.32.3-2.3-2.02.40.31.92.0
Patch foraging water rate 12 sec0.41.64.60.4-0.70.3-1.11.5-1.61.6-1.5-1.22.11.40.60.8
Patch foraging water rate 18 sec2.96.513.01.7-1.7-1.0-2.32.7-3.63.6-2.9-3.22.51.12.22.8
Patch foraging water rate 24 sec4.05.79.91.0-2.00.2-2.83.0-2.62.6-3.1-2.43.11.22.42.4
Patch foraging water rate 6 sec2.13.15.72.0-2.4-1.1-2.21.5-2.02.0-1.7-1.72.0-0.21.31.6
Seeking ratio, delayed vs. immediate footshock0.40.61.60.31.2-1.01.3-0.7-0.40.40.70.0-0.90.6-0.8-0.5
Distance traveled before self-admin0.20.51.5-0.3-0.11.0-0.40.7-0.90.9-0.7-0.8-0.5-0.61.20.5
Distance traveled after self-admin0.61.13.51.0-1.3-0.1-0.80.7-1.21.2-0.9-1.30.2-1.21.90.7
Extensor digitorum longus weight0.10.41.61.3-0.9-0.8-0.30.0-0.70.7-0.1-0.80.40.20.5-0.6
Bone: elastic displacement0.30.41.8-0.91.30.20.70.10.1-0.1-0.00.0-0.31.3-0.70.3
Bone: elastic work0.91.23.80.10.8-0.30.41.0-1.31.3-1.0-1.40.61.90.51.7
Bone: endosteal estimation1.43.46.71.3-1.1-1.50.9-2.42.2-2.22.22.6-0.5-2.3-1.6-1.7
Bone: endosteal perimeter1.22.95.11.6-1.0-2.00.7-2.31.9-1.92.12.0-0.8-2.1-1.6-1.0
Epididymis fat weight0.10.51.8-1.2-0.01.3-0.30.7-0.40.4-0.6-0.40.70.6-0.5-0.6
Delta time in closed arm before/after self-admin0.90.82.4-0.51.1-0.20.8-0.50.9-0.90.61.2-0.11.3-1.6-0.5
Delta time in open arm before/after self-admin1.21.42.51.6-1.4-0.7-1.20.9-1.41.4-1.0-1.51.40.80.80.1
Diff in mean of infusions in LGA sessions0.40.72.2-0.7-0.91.1-1.50.70.2-0.2-0.60.11.0-1.30.7-0.1
Delay discount exponential model param0.20.31.0-0.70.60.50.5-0.20.1-0.10.30.5-0.00.4-0.8-1.0
Extinction: sum of active levers before priming0.81.25.71.9-1.3-2.40.1-0.60.4-0.40.30.20.40.2-1.01.6
Active lever presses in extinction session 61.01.02.70.1-1.1-0.70.1-1.01.7-1.70.91.1-0.1-1.6-0.4-0.5
Bone: final force0.91.42.71.5-0.6-1.0-0.60.9-1.71.7-1.0-1.61.21.10.71.3
Bone: final moment1.11.83.21.6-0.8-0.9-0.81.1-1.81.8-1.3-1.81.51.01.01.5
Food consumed during 24 hour testing period0.71.43.11.5-1.5-0.6-0.90.7-1.61.6-0.8-1.40.1-0.21.80.9
Glucose2.64.26.7-1.32.40.52.4-2.02.6-2.62.22.4-1.90.3-2.2-1.9
Heart weight0.71.13.51.1-1.6-1.2-0.80.3-0.70.7-0.6-0.81.0-1.91.11.1
Delay discount hyperbolic model param0.30.31.2-0.60.60.40.7-0.40.1-0.10.50.5-0.20.3-0.9-1.1
Intermittent access intake day 1-15 change0.31.75.0-2.22.01.20.80.11.2-1.20.11.30.31.8-1.6-0.0
Intermittent access intake escalation0.31.65.4-2.31.91.40.70.11.2-1.20.21.20.21.6-1.4-0.1
Intermittent access intake escalation 20.91.63.4-1.21.80.11.3-0.71.5-1.50.91.6-0.21.7-1.70.4
Intermitt. access day 1 inactive lever presses0.00.10.6-0.0-0.10.0-0.30.10.3-0.3-0.10.20.2-0.1-0.20.8
Intermitt. access day 15 inactive lever presses0.10.41.3-0.80.70.3-0.20.70.2-0.2-0.60.11.11.1-0.30.3
Intermitt. access escalation Index0.10.30.60.8-0.3-0.40.10.2-0.70.7-0.4-0.70.70.60.60.1
Intermittent access day 1 total infusions0.10.32.00.1-0.20.30.4-0.40.2-0.20.40.1-1.0-1.40.4-0.4
Intermittent access day 15 total infusions0.20.42.0-1.41.01.20.60.10.6-0.6-0.00.4-0.20.3-0.10.2
Intermittent access terminal intake (last 3 days)0.10.20.6-0.70.70.80.60.00.5-0.50.00.2-0.10.20.20.5
Intermittent access total infusions0.20.21.0-0.70.21.00.20.3-0.00.0-0.3-0.4-0.2-0.50.80.3
Intermittent access day 1 locomotion0.10.31.2-0.4-0.50.8-0.40.4-0.00.0-0.3-0.1-0.3-1.10.70.2
Intermittent access day 15 total locomotion0.10.51.0-0.90.01.0-0.30.9-0.70.7-1.0-0.20.1-0.70.80.7
Intermittent access total locomotion0.40.51.3-0.6-0.01.1-0.20.9-0.70.7-0.9-0.6-0.0-0.41.10.8
Intermittent access standard deviation0.10.61.7-0.81.0-0.00.9-0.60.9-0.90.70.7-0.20.6-1.30.1
Left kidney weight0.21.43.61.50.3-1.61.9-1.70.7-0.71.50.8-0.80.3-1.2-0.6
Right kidney weight0.53.37.82.10.4-2.82.4-2.71.2-1.22.51.1-2.1-0.6-1.7-0.4
Cocaine induced anxiety0.51.45.7-2.42.41.11.00.30.5-0.5-0.10.30.11.6-1.0-0.4
Post-drug Anxiety0.60.62.8-1.11.70.20.70.5-0.40.4-0.5-0.7-0.21.30.00.9
Baseline Anxiety0.71.12.71.7-1.3-1.1-0.4-0.0-1.01.0-0.3-1.2-0.4-1.11.31.6
Tail length1.26.630.25.5-3.1-5.5-0.2-0.9-1.41.40.2-1.70.4-1.00.62.5
Length with tail1.46.030.55.5-3.4-5.3-0.1-1.3-0.70.70.7-0.71.3-0.4-0.71.5
Length without tail0.31.34.92.2-1.7-1.50.4-1.40.7-0.71.20.70.6-0.7-0.7-1.0
Times rat made contact with spout0.50.52.21.5-1.4-0.2-1.20.3-0.00.0-0.2-0.20.1-0.40.80.4
Lifetime Intake0.10.10.5-0.60.00.70.30.10.0-0.0-0.2-0.5-0.1-0.50.50.2
Liver weight, left0.71.24.42.0-2.1-2.1-0.9-0.1-0.20.2-0.1-0.10.9-1.1-0.10.4
Liver weight, right0.20.41.80.50.40.21.1-0.80.1-0.10.90.3-1.3-0.0-0.0-0.7
Locomotor activity1.11.83.91.5-1.6-0.6-1.51.3-1.31.3-1.4-1.52.00.70.71.1
Locomotor testing distance0.61.42.90.6-0.7-0.4-1.21.4-1.41.4-1.5-1.61.71.10.71.1
Locomotor testing rearing0.20.72.50.9-1.1-0.8-1.10.7-0.70.7-0.8-0.81.60.10.30.5
Locomotion in novel chamber0.50.61.7-0.8-0.31.30.1-0.70.6-0.60.70.8-0.6-1.3-0.1-1.2
Locomotion in novel chamber post-restriction0.10.20.70.10.5-0.90.7-0.2-0.20.20.1-0.40.10.8-0.40.4
Fecal boli incidents, locomotor time 10.10.41.8-0.40.7-0.60.5-0.20.1-0.10.20.0-0.51.2-1.40.3
Change in fecal boli incidents, locomotor task1.82.03.9-1.11.10.41.2-1.31.9-1.91.52.0-1.8-1.2-0.7-1.0
Time >=10cm from walls, locomotor time 11.01.33.2-0.30.5-1.71.3-1.21.5-1.51.11.1-0.3-0.1-1.8-0.1
Bouts of movement, locomotor time 11.92.55.11.10.1-1.81.8-2.32.1-2.12.11.6-1.5-0.9-0.8-0.1
Total resting periods, locomotor time 12.12.45.11.20.2-2.12.0-2.31.9-1.92.01.4-1.5-0.8-0.9-0.0
Rest time, locomotor task time 11.11.84.1-0.11.1-1.02.0-1.81.4-1.41.71.2-2.0-0.2-1.1-0.2
Distance moved, locomotor task time 10.41.23.60.7-0.70.3-1.11.2-1.41.4-1.1-1.21.91.30.50.2
Vertical activity count, locomotor time 10.10.71.6-0.6-0.01.2-0.71.1-0.80.8-0.9-0.61.30.90.5-0.1
Time >=10cm from walls, locomotor time 20.30.82.60.00.2-0.6-0.31.1-1.21.2-1.0-1.01.01.6-0.20.4
Bouts of movement, locomotor time 20.20.74.8-0.1-0.90.4-1.0-0.10.7-0.70.10.8-0.5-2.21.00.3
Total resting periods, locomotor time 20.20.95.8-0.2-0.60.3-0.7-0.41.0-1.00.41.0-0.8-2.40.80.1
Rest time, locomotor task time 22.23.78.1-1.82.30.21.4-1.52.6-2.61.72.8-1.51.0-2.8-0.8
Distance moved, locomotor task time 22.12.77.01.8-1.2-0.6-0.51.2-2.52.5-1.4-2.61.80.91.60.9
Vertical activity count, locomotor time 20.40.93.00.2-0.30.70.30.6-1.71.7-0.8-1.70.80.21.0-0.4
Light reinforcement 12.210.016.43.8-3.0-2.5-2.72.6-4.04.0-3.0-4.13.31.42.53.3
Light reinforcement 21.63.68.01.3-1.1-0.3-1.32.1-2.62.6-2.2-2.81.91.01.71.9
Bone: marrow area1.53.67.01.4-1.1-1.70.9-2.42.3-2.32.32.6-0.5-2.3-1.6-1.7
Bone: maximum diameter1.93.97.41.3-0.5-1.91.3-2.72.4-2.42.62.4-1.2-1.9-2.1-1.5
Bone: maximum force0.20.52.71.30.0-1.70.3-0.3-0.50.50.1-0.5-0.2-0.20.20.8
Bone: maximum moment0.30.52.61.3-0.2-1.60.1-0.0-0.60.6-0.2-0.70.1-0.20.51.0
Mean time between licks in bursts0.42.57.7-1.82.80.21.8-1.11.5-1.51.41.7-1.90.8-1.7-0.8
Mean num. licks in bursts0.61.56.32.5-2.4-1.8-1.4-0.20.1-0.1-0.0-0.21.2-0.90.1-0.1
Cd content in liver0.20.31.11.1-0.1-0.60.4-0.30.3-0.30.30.30.10.40.21.0
Co content in liver1.41.65.82.4-1.3-2.20.3-1.40.8-0.81.20.6-0.6-1.70.10.2
Cu content in liver0.70.81.9-0.6-0.50.8-1.31.4-0.70.7-1.3-0.81.2-0.00.80.7
Fe content in liver1.01.23.80.10.3-0.90.6-1.41.2-1.21.31.0-1.3-1.9-0.5-1.0
K content in liver0.50.51.90.2-1.40.4-1.10.5-0.50.5-0.6-0.40.7-1.00.60.1
Mg content in liver0.80.93.31.0-1.8-0.2-1.40.4-0.40.4-0.5-0.50.3-1.41.30.2
Mn content in liver0.60.71.61.3-1.2-0.6-0.70.5-0.60.6-0.6-0.80.3-0.41.21.2
Na content in liver0.60.62.30.7-1.5-0.5-1.10.30.3-0.3-0.5-0.10.8-1.50.50.5
Rb content in liver1.01.15.32.3-1.5-1.6-0.50.2-0.80.8-0.4-0.90.90.40.60.8
Se content in liver0.20.21.2-0.1-0.2-0.2-1.10.8-0.30.3-0.7-0.20.00.30.00.2
Sr content in liver0.80.72.80.30.9-1.51.1-0.70.3-0.30.60.5-0.40.8-1.7-0.1
Zn content in liver0.20.21.7-0.5-0.20.4-1.30.60.3-0.3-0.50.30.40.0-0.20.2
Bone: minimum diameter1.83.46.91.7-0.5-2.01.4-2.62.1-2.12.52.2-1.1-1.9-1.5-1.4
Time in familiar zone, hab. session 10.50.52.50.60.2-1.60.3-0.80.6-0.60.80.3-1.0-0.5-0.80.1
Time in novel zone, hab. session 10.20.21.3-0.30.20.80.40.10.0-0.0-0.00.00.71.2-0.4-0.4
Total zone transitions, hab. session 10.60.83.0-1.70.81.3-0.20.21.1-1.10.10.8-0.8-0.7-0.1-1.1
Total locomotion distance, hab. session 11.31.88.3-2.92.02.30.30.30.8-0.80.00.8-1.30.4-0.3-1.3
Locomotion velocity, hab. session 11.01.46.5-2.61.62.4-0.10.60.5-0.5-0.30.5-1.00.30.1-1.1
Time in familiar zone, hab. session 20.30.41.40.6-1.1-0.3-1.20.3-0.30.3-0.3-0.5-0.0-1.00.60.1
Time in novel zone, hab. session 20.30.42.6-0.30.70.10.40.4-0.50.5-0.4-0.30.61.6-0.10.5
Total zone transitions, hab. session 20.91.12.7-1.0-0.71.0-1.61.6-0.90.9-1.6-0.90.9-0.31.00.3
Total locomotion distance, hab. session 21.11.43.6-1.90.31.7-1.41.8-0.90.9-1.6-0.60.60.80.90.2
Locomotion velocity, hab. session 20.91.33.3-1.80.31.6-1.11.7-1.01.0-1.6-0.70.60.80.80.3
Novel to familiar place preference ratio1.82.47.3-0.82.1-1.22.7-1.61.1-1.11.51.3-0.71.4-2.3-0.2
Novelty place preference2.32.98.1-0.62.0-1.52.8-2.01.5-1.51.81.6-0.71.2-2.6-0.3
Time in novel zone, NPP test1.92.36.8-0.61.8-1.32.6-1.71.3-1.31.61.4-0.61.1-2.3-0.3
Total zone transitions, NPP test1.11.65.1-1.3-1.11.5-2.31.7-0.60.6-1.6-0.80.9-1.31.50.0
Total locomotion distance, NPP test0.71.02.7-0.8-0.31.2-1.21.3-0.90.9-1.3-1.00.3-0.11.60.3
Locomotion velocity, NPP test0.60.82.3-0.6-0.20.9-1.01.2-0.90.9-1.2-1.10.20.01.50.5
Intraocular pressure0.50.81.7-0.70.80.6-0.51.3-1.01.0-1.2-1.00.41.11.00.8
Delta distance traveled before/after self-admin1.61.74.51.9-2.1-1.3-1.20.6-1.11.1-0.9-1.41.7-0.61.31.0
Delta ambulatory time before/after self-admin0.50.93.01.4-1.4-0.6-1.00.5-0.80.8-0.6-0.81.70.00.70.3
Parametrial fat weight0.40.91.9-0.10.8-0.41.1-1.11.4-1.41.21.0-0.90.2-0.9-0.8
Pavlov. Cond. lever latency1.01.33.00.61.6-1.11.7-1.10.9-0.91.10.9-1.60.9-0.60.6
Pavlov. Cond. magazine entry latency0.30.41.5-0.6-0.90.8-0.70.00.3-0.30.00.30.3-1.2-0.0-0.7
Pavlov. Cond. change in total contacts1.61.74.3-0.9-2.11.5-1.81.1-0.80.8-1.2-0.51.8-1.90.8-0.7
Pavlov. Cond. index score0.50.72.4-0.4-1.60.6-1.30.6-0.50.5-0.7-0.51.2-1.00.3-0.3
Pavlov. Cond. latency score0.40.52.0-0.2-1.40.2-1.00.4-0.60.6-0.5-0.51.1-0.90.1-0.3
Pavlov. Cond. lever contacts0.60.72.1-0.6-1.50.8-1.20.6-0.60.6-0.7-0.51.3-1.20.3-0.6
Pavlov. Cond. magazine entry number1.01.23.21.11.6-1.81.7-0.8-0.00.00.7-0.2-1.41.6-0.50.6
Pavlov. Cond. intertrial magazine entries1.41.72.91.3-0.4-0.6-1.41.5-1.71.7-1.5-1.70.71.31.31.2
Pavlov. Cond. lever-magazine prob. diff.0.70.82.5-0.7-1.61.0-1.30.7-0.50.5-0.7-0.51.2-1.20.4-0.5
Pavlov. Cond. response bias1.11.43.5-0.9-1.91.5-1.91.0-0.40.4-1.0-0.31.6-1.50.7-0.5
Pavlov. Cond. lever latency0.30.41.8-0.61.2-0.40.7-0.40.4-0.40.50.2-1.30.0-0.6-0.3
Pavlov. Cond. magazine entry latency0.91.22.7-0.1-0.91.2-1.21.4-1.11.1-1.4-1.01.20.41.60.8
Pavlov. Cond. change in total contacts0.30.83.40.0-1.30.9-1.00.9-0.60.6-1.0-0.61.80.10.90.4
Pavlov. Cond. index score0.40.72.00.0-1.01.0-1.01.0-0.60.6-1.0-0.41.40.40.90.4
Pavlov. Cond. latency score0.40.71.80.1-0.90.8-1.01.0-0.70.7-1.0-0.51.30.40.90.5
Pavlov. Cond. lever contacts0.20.31.40.6-1.00.1-0.40.2-0.40.4-0.4-0.21.20.00.60.3
Pavlov. Cond. magazine entry number1.41.83.90.40.6-1.21.4-1.81.2-1.21.81.1-2.0-1.3-1.3-1.1
Pavlov. Cond. intertrial magazine entries0.20.51.80.6-0.1-0.10.20.6-1.11.1-0.6-1.30.71.00.40.3
Pavlov. Cond. lever-magazine prob. diff.0.40.71.8-0.2-0.81.1-1.01.0-0.60.6-1.0-0.41.40.40.90.3
Pavlov. Cond. response bias0.30.52.20.1-0.90.7-0.60.6-0.40.4-0.7-0.31.50.30.70.4
Time in closed arm before self-admin0.50.83.5-0.1-0.90.8-0.80.7-0.80.8-0.8-1.20.7-0.91.90.5
Time in closed arm after self-admin0.30.31.0-1.00.50.7-0.10.20.8-0.8-0.10.40.7-0.10.10.4
Time in open arm before self-admin0.60.82.6-0.51.2-0.31.6-0.80.5-0.50.80.7-1.60.2-0.80.3
Time in open arm after self-admin0.80.85.32.3-1.1-1.6-0.0-0.4-0.70.70.2-0.5-0.50.30.2-0.0
Bone: periosteal estimation1.22.95.21.6-0.9-1.81.0-2.31.9-1.92.12.1-0.7-2.0-1.3-1.3
Bone: periosteal perimeter1.12.36.62.4-1.7-2.60.2-1.80.9-0.91.50.9-0.3-2.4-0.7-0.3
Bone: post-yield work1.83.18.20.20.8-1.21.3-2.21.8-1.82.21.9-2.9-2.5-0.7-1.6
Progressive ratio test 1 active lever presses0.10.10.7-0.0-0.20.3-0.1-0.10.3-0.30.20.2-0.7-0.90.1-0.4
Progressive ratio test 1 breakpoint0.10.10.70.1-0.20.2-0.1-0.20.2-0.20.20.2-0.6-0.90.1-0.3
Progressive ratio test 1 inactive lever presses0.00.10.4-0.1-0.2-0.20.1-0.10.6-0.60.10.30.3-0.3-0.20.2
Progressive ratio test 2 active lever presses0.91.33.2-0.3-0.61.1-1.11.4-1.11.1-1.4-1.20.7-0.81.81.0
Progressive ratio test 2 breakpoint1.11.53.8-0.3-0.71.2-1.31.5-1.21.2-1.5-1.30.7-0.91.90.9
Progressive ratio test 2 inactive lever presses0.10.20.8-0.90.40.8-0.20.40.6-0.6-0.20.4-0.0-0.40.2-0.0
Incentive Sensitization - Responses1.33.68.1-0.0-0.91.2-1.52.2-2.62.6-2.3-2.41.3-0.42.81.6
Incentive Sensitization - Breakpoint1.84.19.2-0.0-1.01.3-1.72.4-2.72.7-2.5-2.51.5-0.43.01.8
Sum of active levers in priming session hrs 5-61.41.44.00.7-2.0-0.5-1.6-0.01.7-1.70.00.80.8-1.80.00.6
Progressive ratio0.51.43.40.8-0.8-1.1-0.60.8-1.71.7-1.0-1.80.2-0.31.31.6
Food seeking constrained by brief footshock1.11.42.8-0.50.20.7-0.91.4-1.61.6-1.4-1.60.40.41.71.3
Seeking ratio, punishment vs. effort0.10.11.0-0.40.31.0-0.00.10.1-0.10.00.30.10.10.3-0.6
Retroperitoneal fat weight0.41.64.2-2.10.41.6-1.01.6-0.50.5-1.3-0.41.71.9-1.2-0.3
Reaction time number correct0.62.34.9-1.91.31.5-0.61.9-1.81.8-1.7-1.51.12.20.40.1
Reaction time mean minus median0.10.72.1-1.30.30.50.5-0.70.5-0.50.70.7-1.0-1.4-0.2-1.5
Reaction time mean minus median AUC0.10.62.1-1.30.20.70.7-0.60.3-0.30.50.4-0.8-1.50.1-1.3
Reaction time num false alarms1.52.65.3-0.9-0.01.4-1.42.2-1.91.9-2.1-1.91.30.62.31.2
Reaction time num false alarms AUC1.33.06.6-0.9-0.21.4-1.52.3-2.02.0-2.3-2.21.40.52.61.4
Reaction time trials correct on left0.62.34.9-1.91.31.5-0.61.9-1.81.8-1.7-1.51.12.20.40.1
Reaction time trials on left0.72.34.4-2.01.31.6-0.61.9-1.81.8-1.7-1.41.12.10.40.0
Reaction time mean0.40.96.8-0.6-0.60.3-0.2-0.50.7-0.70.50.6-0.8-2.60.7-1.2
Reaction time mean AUC0.51.27.2-0.8-0.50.4-0.0-0.81.0-1.00.70.8-1.0-2.70.4-1.6
Median of all reaction times0.50.86.3-0.3-0.80.2-0.5-0.40.8-0.80.30.5-0.5-2.50.8-1.0
Reaction time omissions1.82.97.8-2.80.52.7-0.7-0.21.6-1.60.61.7-1.2-2.3-0.5-2.7
Reaction time false alarm rate1.01.55.10.2-0.90.6-1.21.3-1.11.1-1.4-1.40.8-0.52.31.4
Reaction time premature initiation rate0.50.82.80.3-1.0-0.4-0.3-0.71.3-1.30.81.70.5-1.0-0.9-0.4
Reaction time premature initiations0.10.31.0-0.7-0.20.3-0.60.30.3-0.3-0.20.81.00.4-0.8-0.4
Std. dev. reaction times0.31.13.6-1.70.21.30.3-0.40.6-0.60.40.7-0.9-1.90.3-1.7
Reaction time trials completed0.72.34.4-2.01.31.6-0.61.9-1.81.8-1.7-1.41.12.10.40.0
Reaction time trials AUC0.72.55.2-2.01.31.7-0.82.0-1.91.9-1.8-1.51.32.30.40.1
Run reversals in cocaine runway, females0.70.84.51.4-0.8-2.10.6-0.40.2-0.20.1-0.20.80.20.01.3
Run reversals in cocaine runway, males0.91.02.2-0.2-1.50.8-1.30.9-1.51.5-0.9-1.10.9-0.50.5-0.2
Latency to leave start box in cocaine runway0.40.62.4-0.8-0.51.4-0.70.20.7-0.7-0.10.5-0.4-1.50.6-0.6
Latency to leave start box in cocaine runway, F0.20.21.30.1-0.40.3-0.5-0.10.3-0.30.1-0.1-0.7-1.10.5-0.5
Latency to leave start box in cocaine runway, M1.31.32.9-1.70.61.70.5-0.41.6-1.60.61.5-0.7-0.8-0.4-0.8
Std. dev. time between licks in bursts0.71.23.6-1.51.90.61.2-0.91.2-1.21.01.2-1.30.2-0.7-0.7
Total sessions with >9 infusions0.10.20.80.3-0.9-0.10.1-0.20.4-0.40.0-0.30.5-0.80.20.5
Short access day 1 total inactive lever presses0.10.20.9-0.4-0.10.2-0.10.60.1-0.1-0.6-0.20.90.20.20.9
Short access day 10 total inactive lever presses0.10.61.2-0.80.40.5-0.71.1-0.30.3-1.0-0.21.10.90.41.0
Short access day 1 total infusions0.10.20.60.6-0.6-0.40.3-0.30.2-0.20.2-0.20.80.1-0.20.1
Short access day 10 total infusions0.50.92.1-0.60.70.71.3-1.11.0-1.01.10.6-0.9-0.9-0.5-1.5
Short access total infusions0.20.20.6-0.3-0.10.10.8-0.60.7-0.70.50.0-0.1-0.7-0.2-0.2
Short access day 1 locomotion0.20.41.3-0.7-0.20.40.1-0.31.1-1.10.30.70.5-0.3-0.7-0.4
Short access day 10 total locomotion0.10.30.9-0.10.2-0.30.9-0.80.3-0.30.70.4-0.5-0.5-0.5-0.4
Short access total locomotion0.10.10.40.0-0.5-0.20.4-0.20.0-0.0-0.0-0.40.5-0.60.10.3
One hour access (0.3 mA shock)0.81.03.80.5-0.9-0.3-0.81.0-0.90.9-1.1-0.72.01.00.11.2
Compulsive drug intake0.81.13.11.7-1.7-1.4-1.20.4-1.01.0-0.6-0.91.0-0.50.70.5
One hour access (shock baseline)0.10.20.6-0.50.60.30.70.2-0.30.3-0.3-0.40.50.8-0.20.6
Social response proportion0.50.61.80.1-0.4-0.20.7-0.91.0-1.00.90.8-0.0-0.6-0.7-1.4
Social responses0.30.41.7-0.1-0.50.3-0.20.3-0.50.5-0.4-0.61.31.1-0.5-0.8
Social time0.91.44.00.31.2-0.61.8-1.51.0-1.01.60.5-2.0-0.0-0.4-1.1
Soleus weight1.44.211.33.4-3.1-1.7-1.60.9-2.42.4-1.2-2.21.5-0.52.31.1
Bone: stiffness0.10.20.80.30.5-0.90.5-0.6-0.10.10.5-0.1-0.6-0.8-0.1-0.0
Tibialis anterior weight2.27.515.23.2-3.9-1.6-2.52.0-3.23.2-2.4-3.23.40.32.62.1
Time to tail flick, vehicle, before self-admin0.30.31.4-1.20.80.90.00.30.5-0.5-0.2-0.2-0.60.50.10.0
Time to tail flick, vehicle, after self-admin0.81.65.5-2.40.92.3-0.71.00.8-0.8-0.70.81.51.4-0.8-0.5
Time to tail flick, test, before self-admin0.70.83.1-1.61.81.20.70.1-0.10.10.1-0.2-0.41.4-0.6-0.6
Time to tail flick, test, after self-admin1.21.23.6-1.51.91.51.2-0.50.5-0.50.70.8-1.01.4-0.5-1.1
Delta time to tail flick, vehicle, before/after SA0.70.72.7-0.90.31.6-0.71.0-0.40.4-0.70.31.31.2-0.3-0.5
Delta time to tail flick, test, before/after SA0.10.20.60.00.30.20.8-0.50.0-0.00.50.5-0.60.20.2-0.5
Tibia length0.41.14.41.10.8-2.11.7-0.9-0.60.60.6-0.7-0.11.1-1.10.8
Ambulatory time before self-admin0.20.61.5-0.1-0.30.5-0.40.8-1.01.0-0.8-0.9-0.5-0.81.21.1
Ambulatory time after self-admin1.42.25.81.2-1.8-0.1-1.31.2-1.91.9-1.4-1.80.9-0.92.41.2
Bone: tissue strength1.51.63.6-0.30.10.6-1.51.9-1.71.7-1.8-1.50.40.71.50.8
Total heroin consumption0.70.84.4-0.1-1.40.2-0.4-0.61.0-1.00.60.70.0-2.10.3-0.8
Bone: trabecular number0.30.52.30.8-1.2-0.7-0.60.0-0.30.3-0.2-0.50.3-1.50.8-0.1
Bone: trabecular spacing1.31.94.61.00.1-1.0-0.31.1-1.81.8-1.2-1.90.42.10.82.1
Bone: trabecular thickness0.60.93.40.1-0.2-0.90.3-1.01.1-1.10.91.1-0.3-1.9-0.9-0.9
Bone: trabecular tissue density0.30.61.10.9-0.7-0.60.3-1.01.0-1.01.00.50.30.2-0.9-0.5
Water consumed over 24 hours1.42.77.11.3-2.10.4-2.72.0-1.51.5-1.9-1.61.70.21.80.9
Number of responses in last shaping day0.10.20.40.4-0.1-0.40.5-0.40.5-0.50.40.20.30.0-0.6-0.4