Hub : Genes

Spdya

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA XM_039111749.2 0.02 0.02 3.7e-03 0.02 0.02 0.02 0.02 3.2e-03 2.0e-03 3.3e-03 5.1e-03
2 PL alternative polyA XM_006239768.5 0.02 0.02 2.4e-03 0.02 0.02 0.02 0.02 1.9e-03 1.1e-03 2.2e-03 3.2e-03
3 Brain alternative TSS XM_063261529.1 0.03 0.03 3.9e-03 0.02 0.02 0.02 0.02 5.6e-03 7.2e-03 1.1e-02 8.2e-03
4 IC alternative polyA XM_039111749.2 0.08 0.08 6.1e-03 0.03 0.04 0.01 0.04 3.0e-02 1.0e-02 1.8e-01 1.2e-02
5 IC alternative polyA XM_006239768.5 0.09 0.09 4.6e-03 0.03 0.04 0.01 0.04 2.3e-02 6.4e-03 1.5e-01 7.5e-03
6 PL isoform ratio XM_063261529.1 0.02 0.02 6.8e-03 0.01 0.01 0.01 0.01 2.7e-02 1.6e-02 2.3e-02 4.0e-02
7 Brain mRNA stability Spdya 0.03 0.03 2.6e-03 0.02 0.02 0.01 0.01 9.5e-03 1.1e-02 1.4e-02 2.9e-02
8 Brain isoform ratio XM_063261529.1 0.05 0.04 9.8e-05 0.04 0.04 0.04 0.04 2.0e-04 8.8e-05 2.2e-04 2.3e-04
9 BLA alternative TSS XM_063261529.1 0.13 0.1 3.7e-06 0.07 0.08 0.08 0.07 9.3e-05 3.4e-05 5.4e-05 9.5e-05
10 BLA intron excision ratio chr6_29668501_29670804 0.09 0.11 5.1e-03 0.02 0.01 0.02 0.01 2.4e-02 1.5e-01 4.6e-02 6.4e-02
11 NAcc alternative TSS XM_063261529.1 0.05 0.1 3.7e-03 0.02 0.01 0.01 0.02 7.4e-04 3.1e-03 2.3e-03 1.5e-03
12 NAcc alternative polyA XM_006239768.5 0.03 0.02 4.0e-04 0.02 0.02 0.01 0.02 1.9e-04 2.4e-04 6.9e-03 1.4e-04
13 Brain intron excision ratio chr6_29668501_29670804 0.03 0.03 2.6e-03 0.03 0.02 0.02 0.02 2.0e-03 3.0e-03 3.5e-03 3.9e-03
14 NAcc alternative polyA XM_039111749.2 0.03 0.03 2.3e-04 0.02 0.02 0.01 0.03 1.5e-04 1.4e-04 1.6e-02 8.4e-05
15 BLA intron excision ratio chr6_29668501_29674891 0.08 0.09 4.3e-03 0.03 0.04 0.02 0.04 7.5e-03 5.8e-03 3.3e-02 5.6e-03
16 NAcc alternative TSS XM_039111751.2 0.07 0.09 3.4e-04 0.02 0.02 0.02 0.02 1.7e-04 3.5e-04 1.6e-04 3.0e-04
17 NAcc isoform ratio XM_063261529.1 0.18 0.13 2.2e-04 0.02 0.02 0.03 0.02 2.8e-04 2.1e-04 1.0e-04 1.9e-04
18 Adipose gene expression Spdya 0.07 0.24 1.0e-03 0.02 0.02 0.03 0.02 1.9e-03 1.4e-03 4.1e-04 1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density4.78.010.3-2.92.9-2.6-3.03.0-2.93.2-2.9-2.9-2.8-2.83.0-3.0-3.03.02.5-1.1-2.6
Area under the delay curve1.31.52.9-1.41.4-1.4-1.41.4-1.41.7-1.4-1.4-0.4-0.41.0-1.6-1.11.21.2-0.4-1.2
BMI with tail0.10.40.80.7-0.70.70.7-0.70.7-0.90.60.60.70.7-0.40.60.3-0.3-0.70.30.2
BMI without tail0.41.32.81.2-1.21.11.2-1.21.2-0.91.11.11.31.3-0.90.70.8-0.8-1.61.70.6
Body weight1.56.57.62.7-2.72.62.7-2.72.7-2.52.72.72.82.8-2.52.52.5-2.5-2.11.82.3
Weight adjusted by age0.10.10.10.3-0.30.20.3-0.30.3-0.20.30.30.30.3-0.30.20.3-0.3-0.20.20.3
Bone surface2.03.64.8-1.91.9-1.9-1.91.9-1.92.1-1.9-1.8-2.1-2.11.8-1.8-1.81.72.2-1.8-1.3
Bone volume2.34.15.7-2.12.1-1.9-2.12.1-2.12.4-2.0-2.0-2.2-2.22.1-2.1-2.02.02.1-1.2-1.6
Breakpoint value in progressive ratio session0.50.61.0-0.80.8-0.6-0.90.9-0.81.0-0.8-0.8-0.6-0.60.8-1.0-0.80.90.60.1-0.8
Number of licking bursts0.20.30.8-0.50.5-0.5-0.50.5-0.50.9-0.5-0.5-0.5-0.50.4-0.8-0.40.40.30.5-0.7
Context. condit. distance diff. score0.10.10.50.2-0.20.10.2-0.20.2-0.30.20.30.10.1-0.10.50.2-0.30.4-0.70.6
Locomotion velocity, session 10.10.10.70.3-0.30.20.3-0.30.3-0.10.30.30.40.4-0.20.50.1-0.1-0.6-0.00.8
Locomotion distance, session 11.92.43.1-1.61.6-1.6-1.61.6-1.61.5-1.6-1.6-1.5-1.51.7-1.2-1.81.71.5-1.7-0.8
Locomotion velocity, session 20.20.20.50.4-0.40.30.5-0.50.5-0.20.50.50.30.3-0.50.50.5-0.5-0.1-0.00.7
Locomotion distance, session 20.00.00.20.0-0.0-0.00.0-0.00.00.10.00.00.20.20.1-0.0-0.10.1-0.20.40.0
Locomotion velocity, session 30.40.40.6-0.70.7-0.5-0.70.7-0.70.7-0.6-0.7-0.7-0.70.7-0.7-0.70.60.7-0.3-0.7
Locomotion distance, session 30.80.91.5-1.01.0-1.0-1.01.0-1.01.2-1.0-1.0-0.8-0.81.0-1.1-1.01.00.6-0.1-0.9
Stereotopy head waving bouts, day 31.11.32.3-1.21.2-1.0-1.11.1-1.11.1-1.1-1.1-1.4-1.41.1-1.1-1.00.91.5-1.1-0.9
Stereotopy head waving duration, day 30.00.00.1-0.10.10.1-0.10.1-0.10.0-0.1-0.1-0.3-0.30.1-0.1-0.1-0.00.4-0.2-0.2
Locomotion velocity, session 70.70.71.4-0.90.9-1.2-0.80.8-0.80.8-0.9-0.8-0.8-0.80.9-0.8-0.90.90.8-0.7-0.8
Locomotion distance, session 70.00.00.10.2-0.20.10.2-0.20.2-0.10.30.20.20.2-0.20.30.2-0.20.1-0.20.3
Stereotopy head waving bouts, day 70.10.10.2-0.20.2-0.3-0.20.2-0.20.3-0.2-0.3-0.1-0.10.2-0.3-0.20.1-0.30.2-0.4
Stereotopy head waving duration, day 70.40.50.9-0.70.7-0.7-0.70.7-0.70.9-0.8-0.8-0.6-0.60.8-0.9-0.80.70.00.1-0.9
Locomotion velocity, session 80.00.00.40.1-0.10.30.1-0.10.10.20.10.1-0.1-0.1-0.1-0.00.1-0.2-0.10.60.2
Locomotion distance, session 80.20.31.6-0.50.5-0.7-0.40.4-0.40.2-0.4-0.4-0.6-0.60.5-0.1-0.50.40.9-1.3-0.0
Degree of sensitization distance1.21.21.81.1-1.10.91.1-1.11.1-1.41.21.21.11.1-1.21.31.2-1.1-0.70.11.1
Degree of sensitization stereotypy0.10.10.70.2-0.10.10.1-0.10.1-0.10.10.10.30.3-0.10.00.0-0.1-0.80.5-0.1
Conditioned locomotion2.83.25.4-1.81.8-1.8-1.81.8-1.81.3-1.8-1.7-2.1-2.11.6-1.4-1.51.52.3-2.3-1.5
Cocaine response after cond. corrected1.72.14.6-1.51.5-1.4-1.51.5-1.52.2-1.5-1.6-1.3-1.31.5-1.6-1.51.51.0-0.5-0.9
Cocaine response after cond. not corrected2.93.44.4-1.91.9-1.8-1.91.9-1.92.1-1.9-1.9-2.0-2.01.9-1.7-1.91.91.6-1.8-1.2
Cocaine response before conditioning0.91.13.0-1.01.0-1.2-0.90.9-0.90.3-1.0-0.9-1.1-1.11.1-0.6-1.11.11.1-1.7-1.0
Saline control response0.70.92.0-0.90.9-0.9-0.90.9-0.91.4-1.0-1.0-0.7-0.71.2-1.1-1.21.30.20.4-0.6
Bone: connectivity density4.46.99.1-2.72.7-2.4-2.82.8-2.73.0-2.7-2.7-2.6-2.62.8-2.8-2.82.82.4-1.2-2.2
Bone: cortical apparent density0.81.12.3-1.11.1-0.9-1.11.1-1.11.5-1.1-1.1-0.9-0.91.0-1.3-1.01.01.00.2-1.1
Bone: cortical area0.81.22.3-1.11.1-1.3-1.11.1-1.10.9-1.1-1.1-1.2-1.21.1-0.8-1.11.11.1-1.5-0.7
Bone: cortical porosity0.91.02.0-1.01.0-1.1-1.01.0-1.00.8-1.0-1.0-1.0-1.01.0-1.2-1.01.00.7-0.2-1.4
Bone: cortical porosity1.01.12.1-1.11.1-1.2-1.11.1-1.11.0-1.1-1.1-1.0-1.01.1-1.3-1.11.10.70.0-1.5
Bone: cortical thickness0.10.10.5-0.20.2-0.4-0.30.3-0.2-0.0-0.3-0.3-0.2-0.20.40.0-0.40.40.1-0.70.0
Bone: cortical thickness1.61.83.5-1.41.4-1.6-1.31.3-1.31.0-1.4-1.3-1.3-1.31.4-1.0-1.41.41.5-1.9-1.0
Bone: cortical tissue density0.60.81.9-0.90.9-0.8-0.90.9-0.91.4-0.9-0.9-0.8-0.80.9-1.2-0.90.90.80.3-0.9
Condit. Reinf. active minus inactive responses0.30.30.50.6-0.60.40.6-0.60.6-0.20.60.60.60.6-0.60.50.6-0.4-0.60.50.7
Condit. Reinf. active-inactive response ratio0.20.30.60.5-0.50.30.6-0.60.5-0.10.50.50.60.6-0.50.30.5-0.3-0.60.80.4
Condit. Reinf. active responses0.40.51.1-0.70.7-0.8-0.70.7-0.71.1-0.7-0.7-0.7-0.70.8-0.8-0.90.90.6-0.4-0.4
Condit. Reinf. inactive responses1.61.92.6-1.51.5-1.2-1.51.5-1.51.5-1.4-1.4-1.3-1.31.6-1.2-1.61.41.4-1.2-0.9
Incentive salience index mean0.20.20.8-0.40.4-0.6-0.40.4-0.40.9-0.4-0.4-0.4-0.40.4-0.6-0.30.50.20.1-0.2
Condit. Reinf. lever presses1.11.62.9-1.31.3-1.4-1.31.3-1.31.7-1.3-1.3-1.2-1.21.2-1.5-1.21.30.9-0.3-1.1
Condit. Reinf. active minus inactive responses3.14.05.3-2.12.1-1.9-2.02.0-2.01.5-2.0-2.0-2.2-2.21.9-2.0-1.91.82.1-1.6-2.3
Condit. Reinf. active-inactive response ratio0.60.71.2-0.90.9-0.8-0.90.9-0.90.5-0.8-0.8-1.0-1.00.7-0.8-0.60.61.1-1.0-1.1
Condit. Reinf. active responses2.63.65.2-2.02.0-1.9-1.91.9-1.91.3-1.9-1.9-2.1-2.11.8-1.9-1.71.72.1-1.7-2.3
Condit. Reinf. inactive responses1.72.12.6-1.51.5-1.6-1.41.4-1.51.1-1.5-1.5-1.6-1.61.4-1.5-1.41.41.5-1.3-1.6
Condit. Reinf. lever presses1.72.43.5-1.61.6-1.6-1.61.6-1.61.2-1.5-1.5-1.6-1.61.4-1.6-1.31.31.9-1.3-1.8
Condit. Reinf. lever reinforcers received2.23.14.6-1.81.8-1.8-1.81.8-1.81.3-1.8-1.8-1.9-1.91.7-1.8-1.61.61.9-1.4-2.1
Conditioned reinforcement - actives0.20.30.8-0.40.4-0.6-0.30.3-0.40.7-0.4-0.4-0.8-0.80.5-0.5-0.40.40.9-0.6-0.2
Conditioned reinforcement - inactives1.72.53.6-1.61.6-1.6-1.71.7-1.61.8-1.6-1.6-1.3-1.31.6-1.9-1.71.71.2-0.1-1.7
Conditioned locomotion0.50.71.90.8-0.80.60.9-0.90.8-0.20.80.80.90.9-0.90.40.9-0.9-0.61.40.7
Patch foraging indifference point 0 sec0.30.51.90.7-0.70.60.7-0.70.7-0.40.70.70.90.9-0.60.30.6-0.6-0.91.40.4
Patch foraging indifference point AUC0.91.32.8-1.11.1-1.1-1.21.3-1.21.6-1.1-1.2-0.7-0.71.0-1.7-1.01.00.11.1-1.5
Delay disc. indifference point, 0s delay0.60.61.50.8-0.80.70.8-0.80.8-0.90.70.71.21.2-0.80.80.7-0.7-0.80.40.5
Delay disc. indifference point, 16s delay1.11.22.4-1.21.2-1.1-1.21.2-1.21.6-1.2-1.2-0.8-0.81.1-1.4-1.11.10.9-0.3-1.0
Delay disc. indifference point, 2s delay0.10.10.40.1-0.10.00.1-0.10.10.10.10.00.60.6-0.3-0.00.2-0.2-0.30.40.0
Delay disc. indifference point, 24s delay4.65.16.6-2.42.4-2.4-2.32.3-2.32.4-2.3-2.3-1.9-1.92.3-2.3-2.32.32.6-1.8-2.0
Delay disc. indifference point, 4s delay0.10.20.4-0.30.3-0.4-0.30.3-0.30.6-0.3-0.30.40.40.1-0.6-0.10.20.30.6-0.5
Delay disc. indifference point, 8s delay0.91.12.1-1.21.2-1.3-1.21.2-1.21.4-1.2-1.2-0.4-0.40.9-1.3-0.91.00.9-0.5-0.9
Indifference point function ln k0.10.22.40.0-0.00.20.1-0.10.1-0.70.00.1-0.3-0.30.20.6-0.10.10.5-1.50.4
Indifference point function log k0.10.22.40.0-0.00.20.1-0.10.1-0.70.00.1-0.3-0.30.20.6-0.10.10.5-1.50.4
Patch foraging total patch changes 0 sec0.20.41.40.7-0.70.60.7-0.70.7-0.40.60.60.90.9-0.60.30.5-0.6-0.71.20.3
Patch foraging total patch changes 12 sec0.91.22.41.1-1.10.91.0-1.01.1-0.91.11.01.31.3-1.20.81.2-1.2-1.21.60.7
Patch foraging total patch changes 18 sec0.40.66.20.4-0.40.20.3-0.30.30.30.30.30.60.6-0.4-0.40.4-0.4-1.22.5-0.4
Patch foraging total patch changes 24 sec1.42.44.41.6-1.61.31.5-1.51.6-1.31.61.61.81.8-1.81.11.8-1.8-1.32.10.8
Patch foraging total patch changes 6 sec0.20.32.40.3-0.30.00.2-0.20.30.00.30.20.80.8-0.2-0.20.2-0.2-0.91.6-0.2
Patch foraging time to switch 0 sec0.10.20.5-0.40.4-0.5-0.40.4-0.40.2-0.4-0.4-0.4-0.40.4-0.4-0.40.50.3-0.3-0.7
Patch foraging water rate 0 sec0.10.10.20.4-0.40.50.4-0.40.4-0.00.40.40.30.3-0.30.20.3-0.4-0.20.50.5
Patch foraging water rate 12 sec1.02.14.31.6-1.61.51.7-1.71.6-2.11.61.70.90.9-1.41.71.4-1.5-0.5-0.21.1
Patch foraging water rate 18 sec0.50.82.50.7-0.70.50.9-0.90.8-1.40.80.80.30.3-0.61.30.7-0.80.4-1.61.0
Patch foraging water rate 24 sec1.92.73.71.7-1.71.81.7-1.71.7-1.91.71.71.61.6-1.51.61.4-1.5-1.81.21.2
Patch foraging water rate 6 sec1.21.72.41.4-1.41.41.5-1.51.5-1.51.41.51.01.0-1.31.31.3-1.3-0.80.60.9
Seeking ratio, delayed vs. immediate footshock0.40.51.10.7-0.71.00.7-0.60.7-0.70.70.70.70.7-0.71.00.7-0.7-0.60.11.1
Distance traveled before self-admin0.10.11.1-0.10.1-0.1-0.00.0-0.0-0.1-0.00.0-0.5-0.50.10.2-0.00.11.0-1.10.2
Distance traveled after self-admin1.31.62.31.3-1.31.41.3-1.31.3-0.71.31.21.31.3-1.40.91.4-1.4-1.21.51.2
Extensor digitorum longus weight4.818.821.1-4.54.5-4.5-4.54.5-4.54.4-4.5-4.5-4.3-4.34.6-4.6-4.64.63.6-2.3-4.4
Bone: elastic displacement0.81.02.5-1.01.0-1.2-1.01.0-1.00.6-1.0-1.0-1.0-1.01.1-0.6-1.11.10.8-1.6-0.4
Bone: elastic work1.11.53.2-1.21.2-1.4-1.21.2-1.20.8-1.2-1.2-1.2-1.21.3-0.8-1.31.31.2-1.8-0.7
Bone: endosteal estimation0.51.04.1-0.90.9-0.9-0.90.9-0.90.8-0.8-0.8-1.3-1.30.7-0.5-0.60.61.6-2.0-0.3
Bone: endosteal perimeter0.20.41.1-0.60.6-0.6-0.60.6-0.60.6-0.5-0.5-0.8-0.80.4-0.4-0.30.30.9-1.1-0.2
Epididymis fat weight15.252.157.07.5-7.57.57.5-7.57.5-7.27.47.57.47.4-7.37.47.3-7.4-6.84.96.7
Delta time in closed arm before/after self-admin0.00.00.2-0.00.0-0.1-0.10.1-0.00.2-0.0-0.00.00.00.00.1-0.0-0.00.1-0.40.3
Delta time in open arm before/after self-admin0.70.72.4-0.70.7-0.5-0.80.8-0.81.0-0.8-0.9-0.4-0.40.8-1.2-0.80.9-0.71.5-1.1
Diff in mean of infusions in LGA sessions0.20.22.60.1-0.10.30.0-0.00.00.50.0-0.00.20.2-0.1-0.50.1-0.1-0.61.6-0.3
Delay discount exponential model param2.12.34.01.7-1.71.71.7-1.71.7-2.01.71.70.70.7-1.31.91.4-1.4-1.50.61.5
Extinction: sum of active levers before priming0.91.01.3-1.01.0-1.1-1.01.0-1.01.1-1.1-1.0-1.2-1.21.0-1.1-0.90.90.9-0.5-0.9
Active lever presses in extinction session 60.00.00.00.0-0.00.2-0.10.1-0.0-0.20.00.00.20.2-0.00.20.0-0.00.0-0.20.2
Bone: final force0.10.20.4-0.40.4-0.6-0.50.5-0.40.6-0.4-0.4-0.4-0.40.5-0.5-0.50.50.5-0.3-0.3
Bone: final moment0.20.30.4-0.50.5-0.6-0.50.5-0.50.6-0.5-0.5-0.6-0.60.6-0.4-0.60.60.6-0.5-0.2
Food consumed during 24 hour testing period0.10.20.7-0.40.4-0.6-0.50.5-0.40.2-0.4-0.4-0.2-0.20.3-0.3-0.30.30.5-0.8-0.3
Glucose0.60.92.90.9-0.91.30.9-0.90.9-0.60.90.91.01.0-1.00.61.0-1.0-0.81.70.4
Heart weight2.64.15.32.2-2.21.82.2-2.22.2-2.32.12.21.91.9-2.02.12.0-2.1-1.91.11.7
Delay discount hyperbolic model param1.41.53.01.4-1.41.41.4-1.41.4-1.71.41.40.40.4-1.01.61.1-1.1-1.20.31.3
Intermittent access intake day 1-15 change0.20.41.40.4-0.50.20.6-0.60.5-0.80.50.60.20.2-0.60.90.6-0.60.4-1.20.7
Intermittent access intake escalation0.30.51.20.6-0.60.40.8-0.80.7-0.90.70.70.30.3-0.81.00.8-0.80.3-1.10.9
Intermittent access intake escalation 20.60.61.20.7-0.70.50.8-0.80.8-1.00.70.80.50.5-0.91.11.0-1.00.1-1.00.9
Intermitt. access day 1 inactive lever presses0.10.52.1-0.70.7-0.6-0.70.7-0.71.4-0.7-0.7-0.4-0.40.8-0.9-0.80.80.50.3-0.1
Intermitt. access day 15 inactive lever presses1.32.73.6-1.71.7-1.9-1.81.8-1.81.9-1.8-1.8-1.3-1.31.7-1.9-1.71.81.1-0.6-1.5
Intermitt. access escalation Index0.71.04.30.9-0.91.10.7-0.70.8-0.50.80.81.21.2-0.70.50.6-0.6-1.92.10.5
Intermittent access day 1 total infusions2.13.56.2-1.91.9-1.7-2.02.0-2.02.5-1.9-2.0-1.4-1.41.9-2.4-1.92.01.00.5-2.0
Intermittent access day 15 total infusions0.50.81.6-0.90.9-1.0-0.90.9-0.91.3-0.9-0.9-0.9-0.90.8-0.9-0.80.81.0-0.6-0.5
Intermittent access terminal intake (last 3 days)1.11.43.0-1.21.2-1.2-1.21.2-1.21.7-1.3-1.3-1.1-1.11.1-1.5-1.11.11.0-0.2-1.1
Intermittent access total infusions1.21.43.1-1.21.2-1.1-1.21.2-1.21.8-1.2-1.2-1.1-1.11.1-1.4-1.11.11.1-0.2-1.0
Intermittent access day 1 locomotion1.51.93.2-1.51.5-1.3-1.61.6-1.51.8-1.5-1.5-0.8-0.81.4-1.7-1.51.60.80.2-1.4
Intermittent access day 15 total locomotion0.00.00.2-0.10.1-0.1-0.00.0-0.00.4-0.0-0.00.10.1-0.0-0.30.0-0.00.50.5-0.0
Intermittent access total locomotion0.10.10.8-0.20.2-0.1-0.20.2-0.20.7-0.2-0.20.10.10.1-0.5-0.10.20.10.9-0.3
Intermittent access standard deviation0.20.51.4-0.70.7-0.8-0.70.7-0.70.7-0.7-0.7-0.4-0.40.6-0.4-0.60.70.9-1.2-0.1
Left kidney weight0.00.00.2-0.10.1-0.30.0-0.1-0.00.4-0.1-0.1-0.4-0.40.1-0.3-0.0-0.10.3-0.2-0.1
Right kidney weight0.00.20.40.5-0.50.30.6-0.60.6-0.50.50.60.40.4-0.40.20.4-0.5-0.10.30.2
Cocaine induced anxiety0.10.10.7-0.30.3-0.1-0.30.3-0.30.5-0.3-0.3-0.1-0.10.3-0.5-0.30.4-0.00.8-0.4
Post-drug Anxiety1.41.53.71.2-1.21.31.1-1.11.2-0.91.21.21.41.4-1.31.01.2-1.2-1.11.90.9
Baseline Anxiety2.12.42.91.6-1.61.41.6-1.61.6-1.31.61.61.61.6-1.71.51.7-1.7-1.51.21.6
Tail length0.62.33.01.6-1.61.41.7-1.71.6-1.21.61.61.31.3-1.71.41.7-1.7-1.21.11.6
Length with tail1.87.99.92.9-2.92.73.0-3.03.0-2.63.03.02.72.7-3.02.93.0-3.1-2.01.53.0
Length without tail0.72.33.51.5-1.51.51.5-1.51.5-1.71.61.61.51.5-1.71.91.7-1.7-0.5-0.11.8
Times rat made contact with spout2.52.85.2-1.71.7-1.7-1.81.8-1.72.3-1.7-1.7-1.7-1.71.6-1.7-1.61.61.7-1.1-0.8
Lifetime Intake0.91.12.7-1.11.1-1.0-1.11.1-1.11.6-1.1-1.1-0.9-0.90.9-1.3-0.91.00.80.1-0.8
Liver weight, left3.76.27.42.6-2.62.72.5-2.52.6-2.12.62.52.62.6-2.42.32.3-2.4-2.62.32.4
Liver weight, right9.216.119.74.2-4.24.44.1-4.14.1-3.64.14.14.14.1-4.03.64.0-3.9-3.93.93.5
Locomotor activity0.00.10.2-0.20.2-0.3-0.30.3-0.20.4-0.2-0.3-0.0-0.00.3-0.3-0.30.30.20.1-0.2
Locomotor testing distance0.81.42.5-1.21.2-1.3-1.21.2-1.21.6-1.2-1.2-0.9-0.91.2-1.5-1.31.30.8-0.1-1.1
Locomotor testing rearing0.40.81.7-0.90.9-0.9-1.01.0-1.01.3-0.9-1.0-0.3-0.30.9-1.2-0.90.90.40.4-0.9
Locomotion in novel chamber0.70.91.31.0-1.00.90.9-0.91.0-1.11.01.00.80.8-0.91.00.9-0.9-1.00.80.8
Locomotion in novel chamber post-restriction2.03.34.01.9-1.92.01.9-1.91.8-1.41.81.82.02.0-1.81.71.8-1.9-1.61.71.8
Fecal boli incidents, locomotor time 10.50.71.4-0.90.9-0.8-0.90.9-0.90.8-0.9-0.9-1.2-1.20.7-0.8-0.70.60.7-0.4-0.6
Change in fecal boli incidents, locomotor task3.63.64.52.0-2.02.12.0-2.02.0-1.62.02.01.71.7-1.81.71.8-1.8-2.02.01.6
Time >=10cm from walls, locomotor time 10.20.20.5-0.30.3-0.2-0.30.3-0.30.5-0.3-0.3-0.7-0.70.4-0.1-0.30.30.4-0.60.3
Bouts of movement, locomotor time 13.54.05.3-2.12.1-2.1-2.02.0-2.01.7-2.0-2.0-1.8-1.82.0-1.8-2.02.02.3-2.2-1.8
Total resting periods, locomotor time 13.53.95.3-2.02.0-2.2-1.91.9-2.01.6-2.0-2.0-1.9-1.91.9-1.8-1.91.92.3-2.2-1.9
Rest time, locomotor task time 10.10.20.40.3-0.30.20.4-0.40.3-0.30.40.40.00.0-0.50.50.6-0.60.0-0.30.6
Distance moved, locomotor task time 10.60.92.50.9-0.90.90.8-0.80.8-0.70.80.81.41.4-0.70.60.6-0.6-1.31.60.4
Vertical activity count, locomotor time 10.20.40.60.6-0.60.60.6-0.60.6-0.70.60.60.80.8-0.60.70.6-0.5-0.4-0.10.8
Time >=10cm from walls, locomotor time 20.00.00.2-0.10.10.1-0.20.2-0.10.3-0.1-0.1-0.4-0.40.20.1-0.10.10.2-0.20.4
Bouts of movement, locomotor time 20.10.21.90.2-0.20.20.2-0.20.2-0.40.20.3-0.1-0.1-0.30.60.3-0.40.7-1.40.7
Total resting periods, locomotor time 20.10.22.1-0.00.0-0.00.0-0.10.0-0.10.00.1-0.4-0.4-0.10.40.2-0.20.8-1.40.5
Rest time, locomotor task time 21.51.93.0-1.41.4-1.5-1.41.4-1.41.5-1.4-1.4-1.7-1.71.2-1.3-1.11.11.5-1.0-1.0
Distance moved, locomotor task time 21.31.63.31.2-1.21.31.2-1.21.2-1.31.11.11.81.8-1.11.11.0-0.9-1.61.20.8
Vertical activity count, locomotor time 21.11.62.71.2-1.21.21.3-1.31.3-1.61.31.31.31.3-1.21.61.1-1.1-0.9-0.41.5
Light reinforcement 13.17.69.8-2.92.9-2.9-3.03.0-2.92.8-2.9-3.0-2.3-2.33.0-3.0-3.13.12.0-1.0-2.8
Light reinforcement 22.43.74.5-2.12.1-2.1-2.12.1-2.11.9-2.0-2.1-1.6-1.62.0-1.9-2.02.01.9-1.4-1.6
Bone: marrow area0.51.14.3-1.00.9-1.0-0.90.9-0.90.8-0.9-0.8-1.3-1.30.7-0.5-0.60.61.6-2.1-0.3
Bone: maximum diameter1.32.33.0-1.61.6-1.7-1.51.5-1.51.4-1.5-1.5-1.7-1.71.5-1.4-1.41.41.6-1.7-1.1
Bone: maximum force0.20.30.4-0.50.5-0.6-0.50.5-0.50.5-0.5-0.5-0.6-0.60.6-0.4-0.60.60.5-0.5-0.3
Bone: maximum moment0.20.40.6-0.60.6-0.7-0.60.6-0.60.5-0.6-0.6-0.7-0.70.7-0.4-0.70.70.7-0.8-0.3
Mean time between licks in bursts1.53.64.92.0-2.02.02.0-2.02.0-2.22.02.01.81.8-2.11.92.1-2.1-1.51.11.3
Mean num. licks in bursts0.10.21.0-0.30.3-0.4-0.30.3-0.30.4-0.4-0.4-0.4-0.40.4-0.0-0.40.40.5-1.00.4
Cd content in liver0.10.10.5-0.30.3-0.4-0.30.3-0.30.3-0.3-0.3-0.2-0.20.3-0.5-0.40.40.20.4-0.7
Co content in liver7.48.610.2-3.03.1-3.1-3.13.1-3.12.9-3.1-3.1-2.7-2.73.1-3.1-3.23.22.4-1.5-2.9
Cu content in liver0.30.31.3-0.50.5-0.4-0.50.5-0.51.1-0.5-0.5-0.7-0.70.6-0.6-0.60.60.20.10.1
Fe content in liver0.40.52.0-0.70.7-0.7-0.70.7-0.71.4-0.7-0.7-0.7-0.70.6-0.7-0.60.60.7-0.50.1
K content in liver0.40.43.2-0.30.3-0.2-0.20.2-0.30.1-0.2-0.2-0.7-0.70.00.30.1-0.11.1-1.80.7
Mg content in liver0.40.41.1-0.60.6-0.5-0.50.5-0.60.9-0.5-0.5-0.9-0.90.4-0.3-0.40.31.0-1.10.5
Mn content in liver0.00.00.4-0.10.10.0-0.10.1-0.1-0.2-0.1-0.1-0.2-0.20.10.2-0.10.10.3-0.60.2
Na content in liver0.30.31.9-0.40.4-0.4-0.30.3-0.30.5-0.3-0.3-0.8-0.80.2-0.0-0.10.01.0-1.40.5
Rb content in liver0.00.10.2-0.20.2-0.2-0.20.2-0.20.3-0.2-0.2-0.3-0.30.1-0.1-0.10.10.2-0.40.2
Se content in liver0.40.41.20.6-0.60.70.6-0.60.6-0.00.60.60.80.8-0.60.40.6-0.6-0.71.10.7
Sr content in liver0.30.20.70.4-0.40.40.4-0.40.4-0.60.40.5-0.1-0.1-0.50.70.5-0.60.2-0.80.6
Zn content in liver0.50.62.30.8-0.80.80.8-0.80.80.10.70.70.50.5-0.60.40.6-0.6-1.21.50.9
Bone: minimum diameter0.00.10.40.2-0.20.10.2-0.20.2-0.00.20.20.00.0-0.30.40.3-0.3-0.2-0.50.7
Time in familiar zone, hab. session 10.70.71.90.8-0.81.00.8-0.80.8-0.60.80.80.90.9-0.80.60.8-0.7-0.91.40.6
Time in novel zone, hab. session 10.60.60.80.8-0.80.80.8-0.80.8-0.90.80.80.80.8-0.60.80.5-0.4-0.90.70.6
Total zone transitions, hab. session 10.10.20.4-0.40.4-0.5-0.40.4-0.40.0-0.4-0.4-0.5-0.50.6-0.3-0.60.60.3-0.5-0.4
Total locomotion distance, hab. session 10.10.11.3-0.30.3-0.3-0.20.2-0.2-0.2-0.2-0.2-0.3-0.30.30.1-0.30.30.5-1.2-0.1
Locomotion velocity, hab. session 10.91.33.6-1.11.1-1.2-1.11.1-1.10.6-1.1-1.1-1.2-1.21.1-0.7-1.11.11.3-1.9-0.8
Time in familiar zone, hab. session 20.10.10.70.1-0.1-0.10.1-0.10.10.20.10.10.40.40.0-0.2-0.10.1-0.40.8-0.0
Time in novel zone, hab. session 20.30.30.60.5-0.50.80.5-0.50.5-0.70.60.60.40.4-0.60.80.6-0.6-0.2-0.10.7
Total zone transitions, hab. session 20.20.31.8-0.50.5-0.6-0.40.4-0.40.2-0.5-0.4-0.7-0.70.50.0-0.50.40.7-1.30.2
Total locomotion distance, hab. session 20.30.42.9-0.50.5-0.6-0.40.4-0.40.2-0.4-0.4-0.7-0.70.30.0-0.30.20.8-1.70.2
Locomotion velocity, hab. session 20.50.63.1-0.70.7-0.8-0.70.7-0.70.5-0.7-0.7-1.0-1.00.6-0.3-0.50.51.0-1.8-0.1
Novel to familiar place preference ratio0.40.41.70.6-0.60.50.7-0.70.6-1.30.60.60.10.1-0.60.80.6-0.6-0.5-0.30.1
Novelty place preference0.70.82.50.9-0.90.81.0-1.00.9-1.60.90.90.40.4-0.91.10.9-0.9-0.7-0.10.4
Time in novel zone, NPP test1.01.02.71.1-1.10.91.1-1.11.1-1.71.11.10.60.6-1.01.21.1-1.0-0.90.10.5
Total zone transitions, NPP test1.31.93.1-1.51.5-1.5-1.51.5-1.51.3-1.5-1.5-1.2-1.21.4-1.0-1.41.41.4-1.8-0.5
Total locomotion distance, NPP test1.62.27.4-1.51.5-1.6-1.51.5-1.51.1-1.5-1.4-1.4-1.41.4-0.7-1.41.31.8-2.7-0.3
Locomotion velocity, NPP test3.04.38.9-2.22.1-2.2-2.12.1-2.11.8-2.1-2.1-2.0-2.02.0-1.4-2.02.02.2-3.0-1.0
Intraocular pressure3.04.46.12.2-2.22.02.3-2.32.2-1.92.12.22.12.1-2.22.22.1-2.1-1.71.02.5
Delta distance traveled before/after self-admin2.52.64.81.6-1.61.61.5-1.51.5-1.11.51.51.81.8-1.61.21.6-1.6-2.12.21.3
Delta ambulatory time before/after self-admin0.50.62.50.6-0.60.70.5-0.50.5-0.20.60.51.21.2-0.70.30.6-0.6-1.21.60.4
Parametrial fat weight9.722.730.44.8-4.84.84.7-4.74.7-4.44.74.75.55.5-4.74.24.6-4.5-5.35.03.7
Pavlov. Cond. lever latency1.62.03.61.5-1.51.61.5-1.51.5-1.91.41.51.51.5-1.31.41.3-1.3-1.40.90.9
Pavlov. Cond. magazine entry latency0.00.10.1-0.20.2-0.4-0.20.2-0.20.4-0.2-0.2-0.3-0.30.1-0.2-0.10.10.4-0.30.1
Pavlov. Cond. change in total contacts0.10.10.4-0.20.2-0.3-0.20.2-0.10.6-0.1-0.1-0.1-0.10.00.0-0.0-0.00.4-0.60.7
Pavlov. Cond. index score0.60.71.3-0.90.9-1.1-0.90.9-0.91.1-0.8-0.8-0.9-0.90.7-0.8-0.70.71.0-0.8-0.3
Pavlov. Cond. latency score0.50.71.3-0.90.8-1.0-0.80.8-0.81.1-0.8-0.8-0.9-0.90.7-0.7-0.60.61.0-0.9-0.2
Pavlov. Cond. lever contacts1.01.22.4-1.21.2-1.3-1.11.1-1.11.5-1.1-1.1-1.2-1.21.0-1.0-0.90.91.3-0.9-0.5
Pavlov. Cond. magazine entry number0.30.30.70.6-0.60.60.6-0.60.6-0.60.50.50.60.6-0.40.40.4-0.4-0.80.80.3
Pavlov. Cond. intertrial magazine entries1.51.92.9-1.41.4-1.2-1.41.4-1.41.7-1.4-1.4-1.2-1.21.4-1.6-1.51.51.1-0.3-1.3
Pavlov. Cond. lever-magazine prob. diff.1.31.62.4-1.31.3-1.5-1.31.3-1.31.5-1.3-1.3-1.3-1.31.1-1.2-1.11.11.4-1.0-0.8
Pavlov. Cond. response bias1.01.22.0-1.21.2-1.3-1.11.1-1.11.2-1.1-1.1-1.2-1.21.0-1.0-0.90.91.4-1.2-0.7
Pavlov. Cond. lever latency1.21.72.61.3-1.31.31.3-1.31.3-1.01.31.31.31.3-1.21.41.2-1.2-1.50.81.6
Pavlov. Cond. magazine entry latency0.10.10.1-0.30.3-0.2-0.30.3-0.30.1-0.3-0.3-0.3-0.30.3-0.3-0.30.30.2-0.1-0.4
Pavlov. Cond. change in total contacts0.50.81.5-0.90.9-0.9-0.80.8-0.90.7-0.8-0.8-1.1-1.10.7-0.8-0.70.61.2-1.1-0.8
Pavlov. Cond. index score0.70.91.7-1.01.0-0.9-0.90.9-0.90.6-0.9-0.9-1.2-1.20.9-0.9-0.80.81.3-1.0-1.1
Pavlov. Cond. latency score0.60.81.5-0.90.9-0.8-0.90.9-0.90.7-0.9-0.9-1.1-1.10.8-0.8-0.80.81.2-0.9-1.0
Pavlov. Cond. lever contacts0.91.22.3-1.11.1-1.1-1.11.1-1.10.7-1.1-1.0-1.1-1.11.0-1.2-0.90.91.4-0.7-1.5
Pavlov. Cond. magazine entry number0.10.10.20.3-0.30.30.3-0.30.3-0.10.30.30.30.3-0.30.30.3-0.3-0.40.20.5
Pavlov. Cond. intertrial magazine entries2.43.54.92.0-2.01.82.0-2.01.9-1.91.91.92.02.0-1.91.61.8-1.8-2.22.01.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-0.70.7-0.6-0.70.7-0.70.4-0.6-0.6-0.9-0.90.6-0.6-0.50.51.0-0.9-0.8
Pavlov. Cond. response bias1.52.03.0-1.51.5-1.4-1.41.4-1.41.0-1.4-1.4-1.5-1.51.3-1.4-1.31.21.6-1.2-1.7
Time in closed arm before self-admin1.11.41.91.2-1.21.21.2-1.21.2-1.31.11.21.41.4-1.21.21.1-1.1-1.40.80.9
Time in closed arm after self-admin1.81.92.71.4-1.41.41.4-1.41.4-1.21.31.31.61.6-1.51.31.4-1.5-1.41.01.3
Time in open arm before self-admin0.30.31.6-0.50.5-0.5-0.50.5-0.50.5-0.5-0.4-0.7-0.70.4-0.3-0.30.31.3-1.0-0.1
Time in open arm after self-admin2.02.23.2-1.61.6-1.4-1.61.6-1.61.8-1.6-1.6-1.4-1.41.5-1.8-1.51.60.90.1-1.5
Bone: periosteal estimation1.02.05.7-1.41.4-1.5-1.41.4-1.31.2-1.3-1.3-1.7-1.71.3-0.9-1.21.21.8-2.4-0.6
Bone: periosteal perimeter0.50.82.4-0.90.9-1.0-0.90.9-0.90.7-0.8-0.8-1.0-1.00.8-0.5-0.70.71.0-1.5-0.4
Bone: post-yield work0.71.01.4-1.01.0-0.9-1.01.0-1.01.0-1.0-1.0-1.2-1.21.0-0.9-1.01.01.2-0.9-0.8
Progressive ratio test 1 active lever presses0.81.02.0-1.01.0-0.9-1.01.0-1.01.4-1.0-1.0-1.1-1.11.0-1.1-1.01.01.0-0.1-0.7
Progressive ratio test 1 breakpoint0.91.12.1-1.01.0-1.0-1.11.1-1.01.4-1.0-1.0-1.1-1.11.0-1.2-1.01.11.1-0.2-0.8
Progressive ratio test 1 inactive lever presses1.01.42.7-1.21.2-1.2-1.31.3-1.21.6-1.2-1.2-1.0-1.01.2-1.5-1.31.30.40.6-1.2
Progressive ratio test 2 active lever presses0.10.10.6-0.00.00.10.1-0.20.00.60.00.1-0.1-0.1-0.1-0.10.1-0.00.8-0.00.3
Progressive ratio test 2 breakpoint0.10.10.50.1-0.10.10.2-0.20.10.40.10.1-0.0-0.0-0.1-0.00.2-0.10.7-0.10.4
Progressive ratio test 2 inactive lever presses0.10.20.5-0.40.4-0.5-0.30.3-0.30.7-0.3-0.3-0.2-0.20.3-0.5-0.30.40.60.2-0.2
Incentive Sensitization - Responses0.10.10.6-0.00.00.00.2-0.20.00.2-0.00.1-0.1-0.1-0.10.10.1-0.10.7-0.80.4
Incentive Sensitization - Breakpoint0.10.10.40.2-0.20.10.3-0.40.20.10.10.20.10.1-0.30.30.3-0.20.5-0.60.5
Sum of active levers in priming session hrs 5-61.31.21.8-1.11.1-1.2-1.01.0-1.01.0-1.1-1.0-1.3-1.31.1-1.0-1.00.91.3-1.0-0.9
Progressive ratio0.91.51.81.2-1.21.31.2-1.21.2-1.41.31.21.21.2-1.31.31.3-1.2-1.00.71.2
Food seeking constrained by brief footshock1.72.13.0-1.41.4-1.6-1.41.4-1.41.7-1.4-1.5-1.5-1.51.5-1.6-1.51.51.1-0.4-1.3
Seeking ratio, punishment vs. effort1.31.92.7-1.41.4-1.6-1.41.4-1.41.6-1.4-1.4-1.4-1.41.5-1.5-1.51.41.2-0.7-1.3
Retroperitoneal fat weight20.687.9100.99.6-9.69.89.5-9.59.6-8.99.69.510.010.0-9.59.29.3-9.2-9.37.78.5
Reaction time number correct0.51.02.5-1.01.0-1.0-0.90.9-0.90.9-1.0-0.9-1.2-1.21.0-0.7-1.00.91.2-1.6-0.4
Reaction time mean minus median0.00.10.2-0.10.1-0.3-0.20.2-0.20.4-0.2-0.2-0.3-0.30.4-0.3-0.40.5-0.20.2-0.2
Reaction time mean minus median AUC0.00.00.10.0-0.0-0.10.0-0.00.00.0-0.0-0.00.00.00.1-0.0-0.10.2-0.30.2-0.1
Reaction time num false alarms0.30.40.7-0.60.6-0.6-0.60.6-0.60.7-0.6-0.6-0.5-0.50.5-0.8-0.50.50.2-0.0-0.8
Reaction time num false alarms AUC0.40.61.0-0.80.8-0.9-0.80.8-0.80.9-0.9-0.9-0.8-0.80.8-1.0-0.70.80.4-0.3-1.0
Reaction time trials correct on left0.51.02.5-1.01.0-1.0-0.90.9-0.90.9-1.0-0.9-1.2-1.21.0-0.7-1.00.91.2-1.6-0.4
Reaction time trials on left0.61.12.5-1.01.0-1.0-0.90.9-1.01.0-1.0-1.0-1.3-1.31.1-0.7-1.01.01.3-1.6-0.4
Reaction time mean0.71.25.31.1-1.11.01.0-1.01.0-0.20.90.91.01.0-0.80.40.8-0.7-1.82.30.7
Reaction time mean AUC0.61.05.10.9-0.90.80.9-0.90.9-0.10.80.80.90.9-0.70.30.6-0.5-1.82.30.5
Median of all reaction times1.11.57.01.2-1.21.11.1-1.11.1-0.21.01.01.21.2-1.00.40.9-0.8-2.02.70.7
Reaction time omissions0.10.10.2-0.30.3-0.1-0.30.4-0.30.3-0.3-0.40.10.10.3-0.3-0.40.4-0.10.2-0.4
Reaction time false alarm rate0.10.10.3-0.20.2-0.2-0.20.2-0.20.3-0.2-0.30.00.00.1-0.4-0.10.1-0.30.5-0.6
Reaction time premature initiation rate0.10.10.40.4-0.40.50.3-0.30.4-0.50.40.40.30.3-0.30.20.3-0.3-0.30.7-0.1
Reaction time premature initiations0.00.10.2-0.20.2-0.1-0.20.2-0.2-0.1-0.1-0.1-0.4-0.40.3-0.2-0.30.20.5-0.4-0.3
Std. dev. reaction times0.20.31.20.6-0.60.50.6-0.60.6-0.20.50.50.50.5-0.40.30.4-0.3-1.11.00.4
Reaction time trials completed0.61.12.5-1.01.0-1.0-0.90.9-1.01.0-1.0-1.0-1.3-1.31.1-0.7-1.01.01.3-1.6-0.4
Reaction time trials AUC0.71.42.7-1.11.1-1.2-1.01.0-1.11.2-1.1-1.1-1.4-1.41.2-0.9-1.21.11.4-1.6-0.6
Run reversals in cocaine runway, females0.10.10.4-0.10.1-0.1-0.00.0-0.1-0.4-0.0-0.0-0.5-0.5-0.10.00.2-0.10.4-0.6-0.3
Run reversals in cocaine runway, males0.50.51.3-0.70.7-0.8-0.70.7-0.70.4-0.7-0.7-0.9-0.90.6-0.6-0.50.50.6-1.1-0.7
Latency to leave start box in cocaine runway0.30.30.5-0.60.6-0.4-0.60.6-0.60.6-0.6-0.6-0.6-0.60.7-0.6-0.70.60.5-0.1-0.6
Latency to leave start box in cocaine runway, F0.30.30.4-0.60.6-0.4-0.60.6-0.60.5-0.6-0.6-0.6-0.60.7-0.5-0.70.60.6-0.4-0.4
Latency to leave start box in cocaine runway, M0.10.10.90.3-0.30.30.3-0.30.3-0.20.30.30.10.1-0.1-0.00.1-0.2-0.50.9-0.1
Std. dev. time between licks in bursts0.20.33.10.3-0.30.10.3-0.30.20.20.20.20.40.4-0.2-0.50.2-0.2-0.51.8-0.7
Total sessions with >9 infusions0.10.10.4-0.20.2-0.0-0.30.3-0.20.6-0.1-0.2-0.1-0.10.3-0.2-0.30.3-0.30.60.2
Short access day 1 total inactive lever presses4.35.78.3-2.52.5-2.4-2.62.6-2.52.9-2.5-2.5-2.3-2.32.5-2.6-2.52.61.9-0.6-2.0
Short access day 10 total inactive lever presses1.02.53.3-1.71.7-1.6-1.81.8-1.71.7-1.7-1.7-1.2-1.21.6-1.7-1.61.61.4-0.6-1.5
Short access day 1 total infusions0.71.01.9-1.01.0-0.8-1.21.2-1.01.4-1.0-1.0-0.5-0.51.0-1.3-1.01.10.00.9-1.0
Short access day 10 total infusions1.41.83.4-1.41.4-1.2-1.41.4-1.41.8-1.3-1.4-1.5-1.51.3-1.6-1.21.21.0-0.0-1.1
Short access total infusions0.10.10.7-0.30.3-0.2-0.40.4-0.30.8-0.2-0.3-0.0-0.00.2-0.5-0.20.3-0.10.9-0.0
Short access day 1 locomotion1.01.32.3-1.11.1-1.2-1.21.2-1.21.5-1.2-1.2-1.1-1.11.2-1.3-1.21.20.80.0-0.9
Short access day 10 total locomotion1.22.22.8-1.51.5-1.5-1.41.4-1.51.6-1.5-1.5-1.5-1.51.6-1.7-1.61.61.2-0.4-1.5
Short access total locomotion0.00.00.3-0.00.0-0.1-0.10.1-0.00.2-0.0-0.00.20.20.1-0.2-0.10.1-0.10.6-0.0
One hour access (0.3 mA shock)0.20.21.0-0.50.5-0.3-0.50.4-0.50.9-0.4-0.4-0.3-0.30.3-0.6-0.30.41.0-0.1-0.1
Compulsive drug intake0.30.30.80.5-0.50.80.4-0.40.5-0.90.60.60.80.8-0.50.70.5-0.5-0.30.30.5
One hour access (shock baseline)0.71.12.3-1.11.1-1.1-1.00.9-1.01.5-1.1-1.1-1.1-1.10.9-1.3-0.90.91.2-0.3-1.0
Social response proportion0.50.61.70.8-0.80.60.7-0.70.8-0.50.80.80.90.9-0.50.50.4-0.4-1.01.30.5
Social responses0.20.21.40.3-0.3-0.00.3-0.30.30.10.20.20.70.7-0.0-0.1-0.10.1-0.81.20.0
Social time0.81.01.61.1-1.10.81.1-1.11.1-0.71.01.01.21.2-0.90.80.8-0.8-1.31.00.8
Soleus weight5.817.019.4-4.34.3-4.3-4.34.3-4.34.2-4.3-4.3-4.0-4.04.4-4.1-4.44.43.5-2.8-3.6
Bone: stiffness0.00.00.1-0.10.1-0.2-0.10.1-0.10.2-0.1-0.1-0.2-0.20.1-0.1-0.00.00.1-0.0-0.1
Tibialis anterior weight4.515.217.7-4.04.0-4.2-4.14.1-4.13.7-4.1-4.1-3.6-3.64.2-4.1-4.24.22.9-2.2-4.2
Time to tail flick, vehicle, before self-admin0.91.01.81.0-1.00.91.1-1.11.0-0.91.01.00.70.7-1.00.91.1-1.1-1.30.90.6
Time to tail flick, vehicle, after self-admin2.12.83.71.8-1.81.51.9-1.91.8-1.71.71.81.41.4-1.51.81.5-1.5-1.70.81.8
Time to tail flick, test, before self-admin0.10.10.3-0.30.3-0.3-0.30.3-0.30.4-0.3-0.3-0.0-0.00.4-0.2-0.40.50.3-0.20.1
Time to tail flick, test, after self-admin0.20.20.7-0.40.4-0.5-0.30.3-0.30.2-0.3-0.3-0.7-0.70.3-0.3-0.30.20.7-0.9-0.4
Delta time to tail flick, vehicle, before/after SA0.20.21.40.2-0.2-0.00.2-0.20.2-0.40.20.2-0.0-0.00.00.5-0.00.00.6-1.20.6
Delta time to tail flick, test, before/after SA1.61.73.0-1.21.2-1.4-1.11.1-1.20.9-1.2-1.1-1.7-1.71.1-1.0-1.11.01.7-1.7-1.2
Tibia length3.18.510.13.0-3.02.93.0-3.03.0-2.23.03.02.92.9-3.02.83.0-3.0-2.82.33.2
Ambulatory time before self-admin0.10.21.1-0.30.3-0.3-0.20.2-0.20.1-0.2-0.2-0.6-0.60.2-0.1-0.10.21.0-1.0-0.1
Ambulatory time after self-admin0.91.12.21.0-1.01.01.0-1.01.0-0.51.01.01.21.2-1.10.71.1-1.1-1.21.50.8
Bone: tissue strength0.40.40.90.6-0.60.80.6-0.60.6-0.40.60.60.70.7-0.50.50.5-0.5-0.80.90.6
Total heroin consumption3.23.84.6-2.02.0-2.0-2.02.0-2.02.0-2.0-2.0-1.8-1.82.1-2.0-2.12.21.9-1.1-1.7
Bone: trabecular number3.76.28.0-2.52.5-2.3-2.62.6-2.62.8-2.6-2.6-2.4-2.42.7-2.8-2.72.71.9-0.5-2.5
Bone: trabecular spacing1.82.32.81.6-1.61.31.6-1.61.6-1.71.61.61.71.7-1.51.61.4-1.4-1.50.81.5
Bone: trabecular thickness0.60.81.0-0.90.9-0.7-0.90.9-0.91.0-0.9-0.9-0.9-0.90.9-1.0-0.90.90.7-0.2-1.0
Bone: trabecular tissue density0.20.30.7-0.50.5-0.5-0.50.5-0.50.6-0.5-0.5-0.6-0.60.3-0.7-0.30.20.60.0-0.8
Water consumed over 24 hours0.40.61.4-0.80.8-0.7-0.80.8-0.80.9-0.7-0.7-0.7-0.70.6-0.7-0.60.61.2-0.9-0.3
Number of responses in last shaping day0.30.31.40.5-0.50.40.6-0.60.5-0.30.50.60.20.2-0.40.80.4-0.40.2-0.81.2