Spats2l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS XM_006244992.4 0.04 0.03 3.0e-04 0.04 0.03 0.03 0.03 2.1e-04 6.3e-04 1.1e-03 1.3e-03
2 Brain alternative TSS XM_006244992.4 0.03 0.02 1.6e-03 0.02 0.02 0.01 0.01 2.8e-03 4.7e-03 1.4e-02 1.2e-02
3 Brain isoform ratio XM_006244992.4 0.03 0.02 2.2e-03 0.03 0.02 0.02 0.02 1.1e-03 3.6e-03 7.1e-03 7.1e-03
4 PL isoform ratio XM_006244992.4 0.02 0.02 5.7e-03 0.01 0.02 0.02 0.02 8.0e-03 3.6e-03 4.0e-03 5.9e-03
5 Liver gene expression Spats2l 0.07 0.04 1.4e-07 0.06 0.06 0.05 0.05 8.0e-07 5.0e-07 1.2e-06 1.7e-06
6 PL gene expression Spats2l 0.04 0.03 2.7e-03 0 0.02 0.01 0.01 1.1e-01 5.8e-03 2.0e-02 1.6e-02
7 Brain isoform ratio XM_063267199.1 0.03 0.02 6.7e-03 0.02 0.01 0 0.01 5.4e-03 7.4e-02 1.0e-01 7.5e-02
8 pVTA alternative TSS XM_006244992.4 0.05 0.03 1.9e-03 0.05 0.03 0.03 0.03 1.3e-04 1.3e-03 2.3e-03 8.5e-04
9 pVTA intron excision ratio chr9_66814304_66839657 0.07 0.04 1.8e-04 0.05 0.04 0.03 0.04 1.1e-04 2.5e-04 1.7e-03 5.7e-04
10 Liver mRNA stability Spats2l 0.03 0.02 1.7e-03 0.02 0.02 0.02 0.02 3.7e-03 1.3e-03 2.5e-03 4.2e-03
11 PL alternative TSS XM_063267197.1 0.04 0.03 3.1e-03 0.01 0.01 0.02 0.01 1.4e-02 1.2e-02 3.8e-03 9.0e-03
12 pVTA alternative TSS XM_063267197.1 0.09 0.05 4.0e-05 0.07 0.07 0.07 0.07 2.8e-06 3.9e-06 2.5e-06 3.6e-06
13 pVTA intron excision ratio chr9_66814640_66839657 0.06 0.04 7.6e-04 0.04 0.04 0.04 0.04 2.2e-04 1.7e-04 3.6e-04 4.0e-04
14 pVTA alternative TSS XM_063267197.1 0.07 0.04 8.6e-04 0.05 0.05 0.04 0.04 8.8e-05 1.2e-04 5.6e-04 1.6e-04
15 pVTA isoform ratio XM_017596460.3 0.05 0.04 8.1e-03 0.03 0.01 0 0.01 3.7e-03 2.9e-02 1.7e-01 3.8e-02
16 pVTA isoform ratio XM_063267197.1 0.08 0.05 2.5e-04 0.05 0.05 0.05 0.05 5.5e-05 1.1e-04 9.5e-05 1.3e-04
17 Brain alternative TSS XM_063267197.1 0.04 0.03 6.6e-03 0.02 0.02 0.02 0.02 3.7e-03 1.1e-02 3.8e-03 8.1e-03
18 BLA gene expression Spats2l 0.17 0.08 4.7e-07 0.14 0.11 0.13 0.13 7.6e-08 1.3e-06 2.4e-07 2.4e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density1.01.84.41.61.61.6-1.00.9-0.52.10.20.20.90.01.5-1.51.6-1.61.61.61.7
Area under the delay curve0.20.30.60.10.10.1-0.40.40.60.30.70.70.6-0.8-0.50.6-0.50.5-0.5-0.5-0.6
BMI with tail2.58.826.0-5.1-5.1-5.14.4-4.23.1-1.6-3.4-3.4-1.90.6-0.70.9-0.80.8-0.8-1.0-1.0
BMI without tail0.31.66.0-1.9-1.9-1.91.3-1.22.50.6-1.0-1.00.4-0.8-0.71.0-0.70.7-1.0-1.2-1.0
Body weight0.10.41.40.90.90.9-0.90.90.41.20.50.51.0-0.60.30.10.3-0.3-0.1-0.5-0.4
Weight adjusted by age0.41.32.61.11.11.1-0.40.2-0.91.3-0.8-0.8-0.01.01.6-1.61.6-1.61.51.21.0
Bone surface1.63.18.32.92.92.9-2.52.4-0.92.11.81.81.7-0.80.7-0.70.8-0.80.90.80.9
Bone volume1.12.14.92.22.22.2-1.91.7-0.82.01.21.21.3-0.41.0-1.01.1-1.11.11.11.2
Breakpoint value in progressive ratio session0.20.31.00.70.70.7-0.40.3-0.90.10.00.0-0.20.40.4-0.60.4-0.40.41.00.6
Number of licking bursts0.10.51.00.20.20.20.1-0.2-1.0-0.2-0.5-0.5-0.60.90.9-0.90.9-0.90.80.80.9
Context. condit. distance diff. score0.10.10.3-0.5-0.5-0.50.6-0.50.2-0.3-0.2-0.2-0.40.20.0-0.10.0-0.0-0.10.00.1
Locomotion velocity, session 10.60.71.4-1.2-1.2-1.20.7-0.61.1-0.4-0.4-0.4-0.0-0.4-0.81.0-0.80.8-1.0-1.0-1.0
Locomotion distance, session 10.50.61.4-1.0-1.0-1.01.1-1.10.90.4-1.2-1.2-0.30.40.4-0.30.5-0.50.20.30.3
Locomotion velocity, session 20.30.41.5-0.6-0.6-0.60.2-0.11.20.60.00.00.6-0.8-0.70.7-0.70.7-0.7-0.7-0.7
Locomotion distance, session 21.31.96.9-1.0-1.0-1.00.10.02.61.40.20.21.5-1.8-1.61.6-1.51.5-1.5-1.5-1.5
Locomotion velocity, session 30.30.31.5-0.6-0.6-0.60.2-0.11.20.7-0.0-0.00.6-0.7-0.50.5-0.50.5-0.5-0.6-0.6
Locomotion distance, session 30.10.20.40.40.40.4-0.50.50.20.60.50.50.6-0.4-0.10.2-0.10.1-0.2-0.2-0.2
Stereotopy head waving bouts, day 30.50.61.6-0.8-0.8-0.81.2-1.2-0.4-1.3-0.8-0.8-1.31.00.3-0.30.2-0.20.20.20.2
Stereotopy head waving duration, day 30.60.72.0-1.1-1.1-1.11.4-1.40.5-0.5-1.1-1.1-0.80.70.4-0.40.3-0.30.30.30.3
Locomotion velocity, session 70.40.51.2-1.1-1.1-1.11.1-1.00.7-0.6-0.6-0.6-0.60.3-0.20.3-0.30.3-0.5-0.4-0.4
Locomotion distance, session 70.60.71.5-0.7-0.7-0.70.10.01.1-0.10.40.40.5-0.8-1.11.2-1.11.1-1.1-1.2-1.2
Stereotopy head waving bouts, day 70.70.81.51.21.21.2-0.80.7-0.81.20.10.10.40.11.0-1.01.0-1.01.01.01.0
Stereotopy head waving duration, day 70.40.52.00.30.30.3-0.10.00.21.4-0.6-0.60.40.00.8-0.90.9-0.90.90.90.9
Locomotion velocity, session 80.10.10.90.00.00.0-0.00.00.71.00.10.10.5-0.30.1-0.10.1-0.10.00.00.1
Locomotion distance, session 80.10.21.1-0.4-0.4-0.40.3-0.21.00.50.00.00.4-0.5-0.40.4-0.40.4-0.5-0.4-0.4
Degree of sensitization distance0.30.30.8-0.9-0.9-0.90.7-0.70.4-0.5-0.5-0.5-0.40.1-0.30.3-0.30.3-0.2-0.2-0.2
Degree of sensitization stereotypy1.11.35.41.51.51.5-1.51.40.22.30.80.81.6-1.00.4-0.40.5-0.50.50.50.5
Conditioned locomotion1.31.52.51.11.11.1-1.51.60.71.01.61.61.6-1.6-1.11.1-1.01.0-1.0-1.0-0.9
Cocaine response after cond. corrected1.01.53.11.71.71.7-1.81.80.11.21.71.71.6-1.2-0.30.3-0.30.3-0.3-0.2-0.2
Cocaine response after cond. not corrected1.31.94.22.02.02.0-1.61.4-0.91.60.90.91.0-0.11.1-1.21.2-1.21.31.31.3
Cocaine response before conditioning3.64.48.20.00.00.00.9-1.2-2.00.2-2.0-2.0-1.62.42.8-2.92.8-2.82.92.82.8
Saline control response0.20.30.70.10.10.10.1-0.1-0.30.4-0.5-0.5-0.10.50.8-0.80.8-0.80.90.80.8
Bone: connectivity density0.71.24.91.31.31.3-0.90.80.22.20.30.31.1-0.41.0-1.11.1-1.11.21.11.2
Bone: cortical apparent density2.23.511.6-2.8-2.8-2.82.3-2.1-0.1-3.4-1.4-1.4-2.21.1-1.11.0-1.21.2-1.2-1.2-1.2
Bone: cortical area0.91.43.41.21.21.2-1.41.4-0.9-1.01.81.80.4-0.7-1.11.1-1.11.1-1.1-1.1-1.1
Bone: cortical porosity1.82.05.62.42.42.4-1.91.7-1.80.41.31.30.50.20.9-0.70.9-0.90.80.80.8
Bone: cortical porosity2.62.87.62.82.82.8-2.11.9-2.10.81.31.30.60.31.3-1.11.3-1.31.21.21.2
Bone: cortical thickness0.91.55.0-0.8-0.8-0.80.3-0.2-0.2-2.20.60.6-0.7-0.1-1.51.5-1.61.6-1.6-1.6-1.6
Bone: cortical thickness0.91.12.5-1.3-1.3-1.31.5-1.5-0.4-1.5-1.3-1.3-1.61.10.2-0.30.1-0.10.30.30.3
Bone: cortical tissue density2.33.610.8-2.9-2.9-2.92.3-2.20.1-3.3-1.4-1.4-2.11.0-1.11.1-1.31.3-1.3-1.3-1.2
Condit. Reinf. active minus inactive responses1.51.74.41.21.21.2-0.1-0.1-2.1-0.5-0.4-0.4-1.11.51.7-1.61.7-1.71.71.51.5
Condit. Reinf. active-inactive response ratio0.60.71.40.60.60.60.1-0.2-1.2-0.4-0.3-0.3-0.81.01.1-1.01.1-1.11.10.90.9
Condit. Reinf. active responses1.21.63.51.91.91.9-1.00.8-1.90.20.40.4-0.30.81.3-1.31.3-1.31.31.21.2
Condit. Reinf. inactive responses0.30.41.01.01.01.0-1.01.0-0.30.30.90.90.6-0.5-0.20.2-0.20.2-0.3-0.2-0.2
Incentive salience index mean2.02.66.91.81.81.8-0.60.3-2.6-0.3-0.1-0.1-1.11.62.0-2.01.9-1.92.01.91.9
Condit. Reinf. lever presses0.91.33.81.71.71.7-0.90.7-2.0-0.20.60.6-0.50.71.1-1.11.0-1.01.21.21.2
Condit. Reinf. active minus inactive responses1.72.64.51.91.91.9-1.10.9-2.00.8-0.0-0.0-0.11.12.1-1.92.1-2.11.91.81.9
Condit. Reinf. active-inactive response ratio2.23.57.11.21.21.2-0.1-0.2-2.7-0.3-1.0-1.0-1.42.32.6-2.42.5-2.52.42.22.3
Condit. Reinf. active responses1.21.73.41.71.71.7-1.10.9-1.80.60.10.1-0.00.81.6-1.41.7-1.71.51.41.4
Condit. Reinf. inactive responses0.20.20.50.30.30.3-0.70.70.10.40.50.50.7-0.6-0.40.4-0.40.4-0.3-0.3-0.3
Condit. Reinf. lever presses2.02.96.1-0.4-0.4-0.41.3-1.4-2.2-1.5-1.8-1.8-2.32.52.0-1.91.9-1.91.81.81.8
Condit. Reinf. lever reinforcers received1.42.04.01.61.61.6-1.00.8-2.00.5-0.0-0.0-0.21.01.8-1.61.8-1.81.71.61.6
Conditioned reinforcement - actives0.00.10.7-0.5-0.5-0.50.4-0.4-0.2-0.8-0.1-0.1-0.50.2-0.10.1-0.20.2-0.0-0.30.0
Conditioned reinforcement - inactives0.20.63.20.60.60.6-0.70.7-1.3-1.80.70.7-0.4-0.3-0.50.7-0.50.5-0.6-0.9-0.5
Conditioned locomotion0.50.81.6-1.2-1.2-1.20.3-0.21.30.20.10.10.5-1.1-1.11.1-1.11.1-1.1-0.9-0.7
Patch foraging indifference point 0 sec0.20.41.2-0.6-0.6-0.60.8-0.8-0.4-1.1-0.8-0.8-1.01.00.5-0.30.4-0.40.10.30.0
Patch foraging indifference point AUC0.20.51.90.80.80.8-0.40.2-1.4-0.3-0.0-0.0-0.50.60.8-0.70.8-0.80.70.70.8
Delay disc. indifference point, 0s delay0.91.12.9-1.7-1.7-1.71.4-1.31.6-0.0-1.1-1.1-0.2-0.2-0.50.5-0.50.5-0.5-0.4-0.6
Delay disc. indifference point, 16s delay0.30.41.11.11.11.1-0.70.6-0.40.50.60.60.3-0.00.5-0.50.5-0.50.50.50.4
Delay disc. indifference point, 2s delay0.50.51.9-1.1-1.1-1.11.0-0.91.40.5-0.8-0.80.1-0.3-0.30.2-0.20.2-0.2-0.0-0.3
Delay disc. indifference point, 24s delay0.00.10.20.10.10.1-0.20.3-0.0-0.20.40.40.1-0.3-0.20.3-0.20.2-0.2-0.2-0.4
Delay disc. indifference point, 4s delay0.30.41.0-1.0-1.0-1.00.6-0.51.00.1-0.3-0.30.1-0.6-0.50.5-0.50.5-0.5-0.4-0.3
Delay disc. indifference point, 8s delay0.91.53.31.41.41.4-1.71.70.30.71.81.81.5-1.2-0.70.9-0.70.7-0.6-0.8-0.8
Indifference point function ln k0.10.20.9-0.4-0.4-0.40.10.00.90.20.10.10.5-0.5-0.70.5-0.70.7-0.6-0.3-0.5
Indifference point function log k0.10.20.9-0.4-0.4-0.40.10.00.90.20.10.10.5-0.5-0.70.5-0.70.7-0.6-0.3-0.5
Patch foraging total patch changes 0 sec0.41.12.3-0.8-0.8-0.81.2-1.3-0.7-1.3-1.3-1.3-1.51.50.9-0.80.8-0.80.60.70.5
Patch foraging total patch changes 12 sec0.50.71.8-0.2-0.2-0.20.6-0.7-1.2-1.3-0.8-0.8-1.31.20.9-0.70.9-0.90.70.40.4
Patch foraging total patch changes 18 sec0.81.94.9-1.5-1.5-1.51.9-1.9-0.8-2.2-1.7-1.7-2.21.60.6-0.50.6-0.60.40.50.3
Patch foraging total patch changes 24 sec0.20.72.20.40.40.40.2-0.3-1.5-0.6-0.6-0.6-1.01.01.0-1.10.9-0.90.91.11.0
Patch foraging total patch changes 6 sec0.61.02.1-0.2-0.2-0.20.8-0.9-0.50.2-1.2-1.2-0.91.31.5-1.41.4-1.41.21.11.0
Patch foraging time to switch 0 sec0.00.20.5-0.6-0.6-0.60.6-0.50.70.4-0.4-0.40.0-0.0-0.00.00.0-0.00.1-0.1-0.1
Patch foraging water rate 0 sec0.10.20.60.80.80.8-0.70.7-0.4-0.10.70.70.3-0.1-0.10.1-0.10.1-0.20.0-0.0
Patch foraging water rate 12 sec0.10.41.70.00.00.00.1-0.20.51.3-0.5-0.50.40.00.5-0.70.6-0.60.61.00.9
Patch foraging water rate 18 sec0.30.72.20.20.20.20.2-0.4-1.0-0.1-0.5-0.5-0.61.11.0-1.20.9-0.91.21.41.5
Patch foraging water rate 24 sec0.20.21.90.00.00.0-0.40.40.81.40.20.21.0-0.5-0.1-0.0-0.10.10.00.20.2
Patch foraging water rate 6 sec0.10.10.5-0.2-0.2-0.20.00.00.70.40.20.20.4-0.2-0.40.2-0.30.3-0.30.0-0.2
Seeking ratio, delayed vs. immediate footshock0.71.04.71.41.41.4-1.11.10.62.20.50.51.4-0.40.5-0.40.6-0.60.70.0-0.1
Distance traveled before self-admin0.51.02.61.61.61.6-1.51.4-0.71.30.30.30.9-0.30.8-0.60.9-0.90.60.40.3
Distance traveled after self-admin0.20.40.80.80.80.8-0.90.90.20.60.50.50.8-0.40.20.40.3-0.3-0.2-0.8-0.7
Extensor digitorum longus weight1.03.88.2-2.9-2.9-2.91.6-1.32.6-0.6-0.9-0.90.1-1.0-2.02.0-2.02.0-2.1-2.2-2.2
Bone: elastic displacement1.21.52.4-0.7-0.7-0.71.3-1.4-0.5-0.2-1.5-1.5-1.31.41.3-1.41.3-1.31.41.41.4
Bone: elastic work0.10.20.30.10.10.10.1-0.2-0.5-0.1-0.2-0.2-0.30.50.5-0.60.5-0.50.60.60.5
Bone: endosteal estimation1.22.87.22.72.72.7-2.01.8-2.10.91.21.20.50.41.4-1.31.5-1.51.41.41.4
Bone: endosteal perimeter1.12.67.42.72.72.7-2.22.0-1.21.51.51.51.2-0.41.0-0.91.0-1.00.90.91.0
Epididymis fat weight0.52.75.01.01.01.0-1.81.91.41.31.71.72.2-2.2-1.51.8-1.41.4-1.5-1.9-1.9
Delta time in closed arm before/after self-admin0.00.00.20.20.20.2-0.20.1-0.4-0.00.00.0-0.10.10.1-0.10.2-0.20.20.30.1
Delta time in open arm before/after self-admin1.92.26.32.52.52.5-1.91.7-2.10.80.60.60.50.31.2-1.21.2-1.20.91.00.9
Diff in mean of infusions in LGA sessions1.22.14.70.40.40.40.4-0.6-1.10.9-1.3-1.3-0.71.61.9-2.21.8-1.82.02.12.1
Delay discount exponential model param0.10.20.5-0.3-0.3-0.30.4-0.5-0.5-0.4-0.7-0.7-0.60.70.4-0.40.3-0.30.30.30.4
Extinction: sum of active levers before priming0.10.10.30.30.30.3-0.20.1-0.40.4-0.0-0.00.00.40.2-0.50.1-0.10.40.50.5
Active lever presses in extinction session 60.40.40.80.60.60.6-0.80.9-0.1-0.00.80.80.6-0.4-0.50.6-0.50.5-0.6-0.5-0.6
Bone: final force0.71.22.91.61.61.6-1.61.6-1.1-0.11.71.70.6-0.5-0.30.4-0.30.3-0.3-0.3-0.3
Bone: final moment0.30.51.21.11.11.1-1.01.0-1.0-0.31.01.00.2-0.00.00.1-0.00.0-0.1-0.0-0.1
Food consumed during 24 hour testing period0.61.13.0-1.7-1.7-1.71.6-1.50.5-1.0-1.3-1.3-1.00.7-0.10.1-0.20.2-0.2-0.2-0.2
Glucose0.60.92.9-1.7-1.7-1.71.3-1.31.2-0.1-1.1-1.1-0.40.1-0.30.3-0.30.3-0.2-0.4-0.4
Heart weight0.91.53.41.91.91.9-1.21.1-0.81.70.60.60.80.11.0-1.21.1-1.11.31.11.3
Delay discount hyperbolic model param0.20.30.8-0.1-0.1-0.10.4-0.5-0.7-0.5-0.7-0.7-0.70.90.6-0.60.5-0.50.50.40.5
Intermittent access intake day 1-15 change0.31.63.1-1.2-1.2-1.21.6-1.6-0.4-0.6-1.8-1.8-1.41.51.0-1.21.0-1.01.11.11.0
Intermittent access intake escalation0.42.24.4-1.5-1.5-1.51.9-2.0-0.5-0.8-2.1-2.1-1.71.81.2-1.31.1-1.11.21.21.2
Intermittent access intake escalation 20.71.32.4-0.3-0.3-0.30.7-0.9-0.80.2-1.5-1.5-0.91.41.4-1.51.4-1.41.31.41.4
Intermitt. access day 1 inactive lever presses0.33.58.9-3.0-3.0-3.02.8-2.70.3-2.7-1.8-1.8-2.31.20.10.2-0.10.1-0.1-0.0-0.1
Intermitt. access day 15 inactive lever presses0.21.02.1-1.2-1.2-1.21.3-1.3-0.5-0.8-1.4-1.4-1.30.90.7-0.70.7-0.70.60.90.8
Intermitt. access escalation Index0.41.44.2-0.4-0.4-0.4-0.20.41.0-1.21.31.30.4-1.0-1.11.8-1.11.1-1.4-2.1-2.0
Intermittent access day 1 total infusions0.10.41.40.10.10.10.3-0.4-0.8-1.2-0.6-0.6-0.90.70.9-0.30.9-0.90.4-0.20.0
Intermittent access day 15 total infusions0.82.04.2-1.4-1.4-1.41.8-1.9-0.8-1.9-1.8-1.8-2.11.71.1-0.91.1-1.11.00.50.7
Intermittent access terminal intake (last 3 days)1.52.75.0-1.6-1.6-1.62.1-2.1-0.9-1.7-2.1-2.1-2.22.01.4-1.21.4-1.41.31.01.2
Intermittent access total infusions1.11.32.7-1.0-1.0-1.01.3-1.4-0.7-1.5-1.5-1.5-1.61.31.2-0.71.2-1.20.80.40.5
Intermittent access day 1 locomotion0.30.53.0-0.5-0.5-0.50.7-0.7-0.8-1.7-0.6-0.6-1.20.60.4-0.10.4-0.40.0-0.2-0.1
Intermittent access day 15 total locomotion0.20.71.4-0.7-0.7-0.70.9-1.0-0.7-1.0-1.2-1.2-1.10.80.9-0.70.9-0.90.50.50.6
Intermittent access total locomotion0.40.41.1-1.1-1.1-1.11.0-0.90.0-0.9-0.8-0.8-0.80.20.20.00.2-0.2-0.10.10.0
Intermittent access standard deviation0.52.85.4-0.8-0.8-0.81.7-1.9-1.1-1.3-2.2-2.2-2.12.31.9-1.71.9-1.91.81.21.3
Left kidney weight0.00.30.9-0.1-0.1-0.10.3-0.30.61.0-0.9-0.90.20.20.8-0.50.9-0.90.8-0.10.2
Right kidney weight0.10.95.20.40.40.4-0.60.71.92.30.40.41.7-1.3-0.10.4-0.00.0-0.2-0.8-0.7
Cocaine induced anxiety0.41.02.0-0.2-0.2-0.2-0.60.71.10.40.90.91.0-1.4-1.31.3-1.21.2-1.2-1.2-1.2
Post-drug Anxiety0.40.51.6-0.0-0.0-0.0-0.40.41.31.10.40.41.1-1.0-0.60.7-0.60.6-0.5-0.7-0.6
Baseline Anxiety0.50.81.70.70.70.70.0-0.2-0.21.0-0.8-0.8-0.00.91.3-1.11.3-1.31.20.80.8
Tail length2.412.932.55.75.75.7-5.65.4-1.53.34.44.43.7-2.40.10.30.3-0.3-0.2-0.7-0.4
Length with tail2.812.536.96.16.16.1-5.35.0-2.73.03.73.72.9-1.11.3-0.91.4-1.41.00.60.7
Length without tail0.73.510.13.23.23.2-2.32.2-2.01.41.31.30.90.21.4-1.41.5-1.51.31.31.2
Times rat made contact with spout1.01.13.2-1.8-1.8-1.81.2-1.11.1-0.6-0.9-0.9-0.40.0-0.80.8-0.80.8-0.8-0.8-0.8
Lifetime Intake1.01.32.4-1.3-1.3-1.31.5-1.5-0.2-1.4-1.5-1.5-1.51.10.9-0.40.9-0.90.60.20.3
Liver weight, left1.01.73.41.71.71.7-1.81.80.31.31.81.81.7-1.2-0.60.6-0.50.5-0.3-0.6-0.6
Liver weight, right1.32.24.61.11.11.1-0.30.1-1.21.3-0.9-0.9-0.21.12.1-2.12.1-2.12.12.02.1
Locomotor activity0.20.30.7-0.8-0.8-0.80.5-0.40.8-0.3-0.2-0.2-0.0-0.3-0.40.6-0.50.5-0.8-0.7-0.8
Locomotor testing distance0.41.02.4-1.4-1.4-1.41.5-1.50.5-0.5-1.6-1.6-0.90.60.5-0.30.5-0.5-0.00.3-0.0
Locomotor testing rearing0.00.10.4-0.5-0.5-0.50.2-0.10.4-0.0-0.2-0.20.2-0.4-0.20.4-0.20.2-0.6-0.2-0.4
Locomotion in novel chamber5.47.315.1-1.6-1.6-1.63.0-3.2-1.0-0.8-3.9-3.9-2.93.42.9-2.92.8-2.82.92.42.4
Locomotion in novel chamber post-restriction0.61.93.60.20.20.20.6-0.8-1.6-1.0-1.6-1.6-1.51.91.9-1.61.8-1.81.51.51.4
Fecal boli incidents, locomotor time 10.20.40.80.80.80.8-0.40.4-0.80.50.20.2-0.10.20.8-0.90.9-0.90.50.80.8
Change in fecal boli incidents, locomotor task0.30.30.8-0.6-0.6-0.60.3-0.20.6-0.60.20.20.0-0.3-0.70.7-0.70.7-0.5-0.5-0.9
Time >=10cm from walls, locomotor time 10.30.41.10.40.40.4-0.60.7-0.3-0.51.11.10.2-0.5-0.50.7-0.50.5-0.8-0.8-0.6
Bouts of movement, locomotor time 11.21.55.60.70.70.70.3-0.5-2.4-2.0-0.2-0.2-1.81.81.3-1.21.2-1.21.21.01.1
Total resting periods, locomotor time 11.31.57.20.10.10.10.9-1.0-2.1-2.7-0.5-0.5-2.21.91.0-0.90.8-0.80.80.60.7
Rest time, locomotor task time 11.01.58.3-0.3-0.3-0.30.3-0.2-0.5-2.91.01.0-1.1-0.0-1.21.4-1.41.4-1.4-1.9-1.7
Distance moved, locomotor task time 10.61.66.51.41.41.4-1.91.90.42.51.01.02.1-1.3-0.00.10.1-0.1-0.20.30.2
Vertical activity count, locomotor time 10.10.63.00.60.60.6-1.11.10.61.70.50.51.5-1.0-0.20.3-0.10.1-0.40.1-0.0
Time >=10cm from walls, locomotor time 20.41.23.0-0.6-0.6-0.6-0.30.41.70.90.60.61.3-1.5-1.21.3-1.11.1-1.5-1.2-1.3
Bouts of movement, locomotor time 20.00.10.30.20.20.20.2-0.3-0.00.0-0.2-0.2-0.20.50.3-0.40.2-0.20.40.40.4
Total resting periods, locomotor time 20.10.20.80.10.10.10.4-0.5-0.5-0.6-0.4-0.4-0.70.90.4-0.60.4-0.40.50.50.5
Rest time, locomotor task time 20.61.07.7-0.4-0.4-0.40.5-0.5-1.0-2.80.60.6-1.40.6-0.80.7-0.90.9-0.8-1.1-0.8
Distance moved, locomotor task time 20.20.32.00.30.30.3-0.70.70.71.40.20.21.2-0.50.2-0.00.3-0.30.10.10.1
Vertical activity count, locomotor time 20.30.83.9-1.3-1.3-1.30.9-0.72.00.9-0.8-0.80.6-0.6-0.20.4-0.10.1-0.6-0.6-0.4
Light reinforcement 11.04.311.0-3.3-3.3-3.32.1-1.82.8-0.8-0.9-0.9-0.2-1.0-1.91.9-1.91.9-2.0-1.8-1.9
Light reinforcement 20.20.40.90.20.20.2-0.60.60.90.80.90.91.0-0.9-0.60.7-0.50.5-0.4-0.7-0.6
Bone: marrow area1.12.77.02.62.62.6-1.91.7-2.10.81.21.20.50.41.4-1.31.4-1.41.31.41.4
Bone: maximum diameter1.12.25.22.32.32.3-2.22.2-1.6-0.32.32.30.8-0.6-0.40.5-0.40.4-0.4-0.4-0.4
Bone: maximum force0.51.02.81.71.71.7-1.41.3-0.90.51.21.20.6-0.20.3-0.20.3-0.30.30.30.3
Bone: maximum moment0.20.41.01.01.01.0-0.70.6-0.80.30.40.40.10.20.6-0.50.6-0.60.50.60.5
Mean time between licks in bursts0.53.26.3-0.9-0.9-0.9-0.20.42.1-0.11.11.11.2-1.9-2.42.4-2.42.4-2.5-2.5-2.5
Mean num. licks in bursts0.61.63.1-1.5-1.5-1.50.8-0.61.8-0.50.00.00.3-0.9-1.61.5-1.61.6-1.6-1.5-1.5
Cd content in liver0.00.00.1-0.0-0.0-0.0-0.00.00.40.20.20.20.2-0.2-0.10.2-0.10.1-0.1-0.1-0.2
Co content in liver0.50.61.4-0.2-0.2-0.20.6-0.7-1.1-1.0-0.6-0.6-1.21.20.8-0.90.8-0.80.71.00.8
Cu content in liver0.10.20.40.50.50.5-0.60.6-0.20.20.60.60.4-0.4-0.20.3-0.20.2-0.3-0.2-0.2
Fe content in liver1.72.24.41.01.01.00.1-0.3-1.30.6-0.8-0.8-0.61.42.1-2.12.1-2.12.12.12.1
K content in liver0.80.81.70.90.90.9-1.21.2-0.20.11.31.30.8-0.8-0.70.7-0.70.7-0.7-0.6-0.7
Mg content in liver0.10.10.50.70.70.7-0.40.4-0.40.10.30.30.10.10.2-0.20.2-0.20.20.30.3
Mn content in liver1.41.65.8-1.5-1.5-1.51.8-1.8-0.4-2.4-1.1-1.1-1.91.3-0.20.1-0.30.3-0.3-0.3-0.4
Na content in liver0.80.92.41.51.51.5-1.41.4-0.80.41.31.30.7-0.5-0.10.1-0.00.0-0.10.30.1
Rb content in liver0.80.92.40.90.90.9-1.11.21.01.41.21.21.5-1.3-0.60.6-0.50.5-0.5-0.4-0.5
Se content in liver0.00.00.10.30.30.3-0.30.2-0.20.10.20.20.1-0.10.0-0.00.0-0.0-0.00.00.1
Sr content in liver0.70.61.4-0.4-0.4-0.4-0.10.20.2-1.10.70.7-0.0-0.5-1.11.2-1.11.1-1.1-1.1-1.2
Zn content in liver0.30.40.70.10.10.1-0.30.40.3-0.30.60.60.3-0.6-0.80.8-0.80.8-0.9-0.8-0.8
Bone: minimum diameter0.51.02.61.61.61.6-1.31.3-1.5-0.61.31.30.1-0.0-0.10.1-0.10.1-0.1-0.1-0.1
Time in familiar zone, hab. session 11.41.53.30.50.50.50.3-0.5-0.41.1-0.9-0.9-0.31.11.7-1.81.8-1.81.71.81.8
Time in novel zone, hab. session 11.01.12.3-0.2-0.2-0.2-0.40.50.2-0.90.90.90.2-0.9-1.51.5-1.51.5-1.4-1.5-1.5
Total zone transitions, hab. session 10.20.31.20.80.80.8-0.60.5-0.11.10.00.00.6-0.10.5-0.50.6-0.60.40.60.5
Total locomotion distance, hab. session 11.11.52.81.21.21.2-0.40.2-1.70.1-0.4-0.4-0.61.21.7-1.61.7-1.71.61.61.6
Locomotion velocity, hab. session 10.71.02.11.11.11.1-0.50.3-1.5-0.0-0.2-0.2-0.41.01.3-1.21.2-1.21.21.21.2
Time in familiar zone, hab. session 21.31.52.9-0.7-0.7-0.71.2-1.3-1.3-1.2-1.5-1.5-1.71.71.2-1.21.1-1.11.21.21.2
Time in novel zone, hab. session 20.91.02.1-0.3-0.3-0.3-0.30.51.50.50.70.71.1-1.3-1.31.3-1.31.3-1.3-1.3-1.3
Total zone transitions, hab. session 20.40.51.9-1.1-1.1-1.10.7-0.61.40.7-0.6-0.60.4-0.5-0.50.4-0.40.4-0.5-0.4-0.4
Total locomotion distance, hab. session 20.30.31.3-0.9-0.9-0.90.6-0.61.20.6-0.7-0.70.3-0.3-0.20.2-0.20.2-0.3-0.2-0.2
Locomotion velocity, hab. session 20.20.31.2-0.9-0.9-0.90.5-0.51.10.5-0.5-0.50.3-0.3-0.30.4-0.30.3-0.4-0.3-0.3
Novel to familiar place preference ratio0.20.21.0-0.5-0.5-0.50.2-0.11.00.7-0.2-0.20.5-0.6-0.40.4-0.40.4-0.4-0.4-0.3
Novelty place preference0.10.20.7-0.5-0.5-0.50.2-0.20.90.6-0.3-0.30.4-0.4-0.30.2-0.20.2-0.2-0.2-0.2
Time in novel zone, NPP test0.20.20.8-0.6-0.6-0.60.4-0.30.90.7-0.5-0.50.3-0.3-0.10.1-0.00.0-0.0-0.0-0.0
Total zone transitions, NPP test0.10.10.20.00.00.00.1-0.1-0.00.4-0.4-0.4-0.00.20.4-0.40.4-0.40.30.40.4
Total locomotion distance, NPP test1.11.52.7-0.4-0.4-0.41.1-1.3-0.7-0.2-1.6-1.6-1.21.61.5-1.41.5-1.51.31.41.4
Locomotion velocity, NPP test0.91.32.5-0.6-0.6-0.61.2-1.3-0.7-0.6-1.6-1.6-1.31.61.3-1.21.2-1.21.11.11.1
Intraocular pressure1.72.86.7-2.6-2.6-2.62.6-2.50.5-1.9-2.0-2.0-1.91.30.3-0.10.2-0.2-0.1-0.0-0.1
Delta distance traveled before/after self-admin0.40.41.1-0.9-0.9-0.90.6-0.50.8-0.70.00.0-0.2-0.1-0.40.8-0.40.4-0.7-1.1-0.9
Delta ambulatory time before/after self-admin0.71.12.7-0.9-0.9-0.90.3-0.10.9-1.20.70.70.0-0.7-1.21.5-1.21.2-1.5-1.6-1.5
Parametrial fat weight1.02.45.6-1.1-1.1-1.10.20.11.6-0.70.70.70.6-1.4-2.02.2-2.02.0-2.2-2.4-2.3
Pavlov. Cond. lever latency1.01.22.5-1.2-1.2-1.20.6-0.41.5-0.40.10.10.2-0.8-1.41.4-1.41.4-1.6-1.5-1.5
Pavlov. Cond. magazine entry latency1.92.55.21.11.11.1-0.1-0.1-2.3-0.2-0.7-0.7-1.11.82.1-2.12.1-2.12.22.02.0
Pavlov. Cond. change in total contacts1.82.04.21.01.01.0-0.1-0.2-1.70.2-0.7-0.7-0.91.41.9-1.91.9-1.92.01.91.9
Pavlov. Cond. index score2.02.66.11.31.31.3-0.40.1-2.5-0.2-0.4-0.4-1.01.72.1-2.12.0-2.02.32.12.1
Pavlov. Cond. latency score2.22.85.91.51.51.5-0.50.2-2.40.1-0.4-0.4-0.81.62.2-2.22.2-2.22.42.22.2
Pavlov. Cond. lever contacts1.21.53.30.90.90.9-0.1-0.0-1.70.0-0.4-0.4-0.71.21.6-1.71.5-1.51.81.71.7
Pavlov. Cond. magazine entry number1.51.94.0-1.2-1.2-1.20.3-0.11.9-0.10.40.40.7-1.4-1.91.8-1.81.8-2.0-1.8-1.8
Pavlov. Cond. intertrial magazine entries0.40.51.00.90.90.9-0.80.90.41.00.80.80.9-0.9-0.30.3-0.30.3-0.3-0.4-0.3
Pavlov. Cond. lever-magazine prob. diff.2.02.56.11.21.21.2-0.1-0.1-2.5-0.5-0.6-0.6-1.21.82.0-2.12.0-2.02.22.12.0
Pavlov. Cond. response bias1.62.05.21.31.31.3-0.50.2-2.3-0.3-0.1-0.1-0.91.41.8-1.81.7-1.72.01.71.7
Pavlov. Cond. lever latency1.72.45.80.50.50.5-1.21.42.11.91.51.52.3-2.4-1.61.5-1.51.5-1.4-1.4-1.4
Pavlov. Cond. magazine entry latency0.50.82.2-0.4-0.4-0.40.8-0.9-1.2-1.5-0.9-0.9-1.51.40.7-0.60.7-0.70.50.50.5
Pavlov. Cond. change in total contacts0.61.57.71.11.11.1-0.40.2-2.8-1.70.10.1-1.41.61.2-1.01.1-1.11.00.90.9
Pavlov. Cond. index score1.01.55.30.10.10.10.6-0.7-2.3-2.0-0.8-0.8-2.02.01.2-1.11.1-1.11.01.00.9
Pavlov. Cond. latency score0.91.55.10.00.00.00.6-0.8-2.3-2.0-0.8-0.8-2.02.01.2-1.11.1-1.11.00.90.9
Pavlov. Cond. lever contacts2.13.17.3-0.2-0.2-0.21.1-1.3-2.6-2.0-1.6-1.6-2.42.72.0-1.91.9-1.91.81.81.7
Pavlov. Cond. magazine entry number0.40.62.4-0.0-0.0-0.0-0.40.51.51.50.40.41.3-1.2-0.70.5-0.60.6-0.4-0.3-0.4
Pavlov. Cond. intertrial magazine entries0.20.42.2-0.0-0.0-0.00.1-0.20.71.5-0.7-0.70.5-0.10.6-0.60.7-0.70.70.70.7
Pavlov. Cond. lever-magazine prob. diff.0.91.35.20.10.10.10.5-0.6-2.3-2.0-0.7-0.7-1.91.81.1-1.01.0-1.00.90.80.8
Pavlov. Cond. response bias1.52.14.8-0.1-0.1-0.10.9-1.0-2.2-1.6-1.3-1.3-2.02.21.6-1.51.6-1.61.41.41.4
Time in closed arm before self-admin0.50.92.81.71.71.7-1.11.0-1.10.40.60.60.20.20.7-0.60.8-0.80.80.30.7
Time in closed arm after self-admin0.50.61.11.11.11.1-0.80.7-0.60.90.10.10.40.00.8-0.70.9-0.90.90.40.9
Time in open arm before self-admin2.73.38.2-2.9-2.9-2.91.9-1.71.8-1.7-0.5-0.5-0.7-0.3-1.61.7-1.71.7-1.8-1.6-1.7
Time in open arm after self-admin0.40.42.00.80.80.8-0.50.4-1.4-0.60.20.2-0.50.80.7-0.60.5-0.50.20.40.3
Bone: periosteal estimation1.02.47.02.72.72.7-2.32.1-2.00.12.02.00.6-0.20.4-0.30.4-0.40.30.30.3
Bone: periosteal perimeter0.71.44.22.12.12.1-1.61.6-1.40.41.41.40.6-0.10.5-0.40.5-0.50.40.40.4
Bone: post-yield work0.30.50.9-0.3-0.3-0.30.7-0.8-0.00.1-0.9-0.9-0.50.80.9-0.80.8-0.80.70.70.8
Progressive ratio test 1 active lever presses1.11.94.4-1.1-1.1-1.11.7-1.7-1.0-2.1-1.7-1.7-2.11.61.2-0.81.2-1.20.90.60.6
Progressive ratio test 1 breakpoint1.01.73.7-0.9-0.9-0.91.5-1.5-1.0-1.8-1.6-1.6-1.91.61.3-0.91.3-1.31.00.70.7
Progressive ratio test 1 inactive lever presses1.33.48.8-3.0-3.0-3.02.7-2.60.9-2.7-1.8-1.8-2.00.7-0.20.7-0.20.2-0.5-0.9-0.7
Progressive ratio test 2 active lever presses0.81.14.4-0.6-0.6-0.61.0-1.1-1.2-2.1-1.0-1.0-1.71.30.9-0.60.9-0.90.70.20.5
Progressive ratio test 2 breakpoint0.91.24.2-0.7-0.7-0.71.1-1.1-1.2-2.0-1.1-1.1-1.81.41.0-0.60.9-0.90.70.20.5
Progressive ratio test 2 inactive lever presses0.41.35.5-1.4-1.4-1.41.4-1.4-0.8-2.4-1.3-1.3-1.81.00.5-0.10.5-0.50.0-0.00.2
Incentive Sensitization - Responses0.10.30.80.60.60.6-0.70.7-0.9-0.90.60.6-0.1-0.0-0.20.3-0.20.2-0.2-0.6-0.2
Incentive Sensitization - Breakpoint0.10.30.80.50.50.5-0.70.7-0.8-0.90.70.7-0.0-0.2-0.30.4-0.30.3-0.4-0.7-0.4
Sum of active levers in priming session hrs 5-61.81.73.31.01.01.0-1.51.60.20.41.81.81.3-1.6-1.51.2-1.41.4-1.6-0.9-1.0
Progressive ratio0.20.72.2-0.5-0.5-0.50.2-0.00.7-1.20.40.4-0.0-0.4-0.91.3-1.01.0-1.0-1.3-1.5
Food seeking constrained by brief footshock0.70.92.10.40.40.40.1-0.3-0.80.2-0.7-0.7-0.41.21.4-1.31.4-1.41.21.21.5
Seeking ratio, punishment vs. effort0.71.74.51.41.41.4-0.90.7-0.82.10.10.10.70.31.3-1.71.3-1.31.31.91.9
Retroperitoneal fat weight0.52.55.4-0.9-0.9-0.9-0.00.32.10.00.80.81.1-1.7-2.02.2-2.02.0-2.2-2.3-2.3
Reaction time number correct0.20.81.6-0.8-0.8-0.81.1-1.10.20.2-1.3-1.3-0.60.90.8-0.80.8-0.80.70.80.9
Reaction time mean minus median0.00.00.00.10.10.1-0.10.1-0.10.0-0.0-0.00.1-0.2-0.0-0.0-0.00.0-0.1-0.10.1
Reaction time mean minus median AUC0.10.61.0-0.2-0.2-0.20.6-0.7-0.9-0.6-0.8-0.8-1.01.00.8-0.90.8-0.80.70.80.9
Reaction time num false alarms1.01.63.4-1.5-1.5-1.50.9-0.71.9-0.60.00.00.2-0.8-1.31.5-1.41.4-1.5-1.8-1.7
Reaction time num false alarms AUC0.81.94.2-1.6-1.6-1.60.9-0.62.0-0.40.10.10.3-0.9-1.41.6-1.51.5-1.6-2.0-1.8
Reaction time trials correct on left0.20.81.6-0.8-0.8-0.81.1-1.10.20.2-1.3-1.3-0.60.90.8-0.80.8-0.80.70.80.9
Reaction time trials on left0.20.71.5-0.8-0.8-0.81.0-1.10.20.3-1.2-1.2-0.60.90.8-0.80.8-0.80.70.80.8
Reaction time mean0.92.04.11.91.91.9-2.02.0-0.7-0.32.02.01.0-1.1-0.91.0-0.90.9-1.0-1.3-1.1
Reaction time mean AUC0.71.73.51.51.51.5-1.71.7-0.6-0.41.91.90.9-1.1-1.01.1-0.90.9-1.1-1.3-1.1
Median of all reaction times2.03.26.82.32.32.3-2.42.5-0.9-0.52.62.61.2-1.3-1.11.3-1.11.1-1.2-1.6-1.4
Reaction time omissions0.10.20.70.30.30.3-0.50.60.50.70.40.40.8-0.8-0.40.4-0.20.2-0.5-0.4-0.4
Reaction time false alarm rate1.31.74.4-0.9-0.9-0.90.10.11.6-0.50.80.80.6-1.3-1.61.8-1.71.7-1.7-2.1-2.0
Reaction time premature initiation rate1.32.14.3-0.4-0.4-0.41.1-1.3-1.5-1.0-1.6-1.6-1.82.11.6-1.71.5-1.51.61.71.6
Reaction time premature initiations0.92.95.3-0.9-0.9-0.91.7-1.8-1.2-0.8-2.1-2.1-1.92.31.8-1.91.7-1.71.81.91.9
Std. dev. reaction times0.10.51.31.11.11.1-1.11.1-0.50.50.70.70.6-0.5-0.0-0.00.0-0.0-0.2-0.2-0.0
Reaction time trials completed0.20.71.5-0.8-0.8-0.81.0-1.10.20.3-1.2-1.2-0.60.90.8-0.80.8-0.80.70.80.8
Reaction time trials AUC0.20.61.2-0.7-0.7-0.70.9-1.00.20.2-1.1-1.1-0.50.80.7-0.70.7-0.70.60.70.7
Run reversals in cocaine runway, females0.00.00.1-0.1-0.1-0.10.1-0.1-0.1-0.10.10.1-0.1-0.1-0.10.1-0.10.1-0.3-0.1-0.0
Run reversals in cocaine runway, males0.70.81.90.50.50.50.4-0.5-1.4-0.8-0.7-0.7-1.21.31.1-1.11.0-1.01.00.80.9
Latency to leave start box in cocaine runway1.62.26.7-2.6-2.6-2.62.1-2.01.4-1.3-1.3-1.3-1.00.2-0.70.7-0.70.7-0.8-0.7-0.6
Latency to leave start box in cocaine runway, F1.51.95.0-2.2-2.2-2.21.3-1.11.4-1.0-0.4-0.4-0.3-0.7-1.41.4-1.41.4-1.6-1.0-0.9
Latency to leave start box in cocaine runway, M2.32.25.0-1.4-1.4-1.42.1-2.20.4-0.6-2.2-2.2-1.51.61.3-1.11.2-1.21.20.60.7
Std. dev. time between licks in bursts0.40.71.9-1.4-1.4-1.41.0-0.90.8-0.7-0.7-0.7-0.40.1-0.60.7-0.70.7-0.7-0.8-0.8
Total sessions with >9 infusions1.72.14.6-2.0-2.0-2.02.1-2.1-0.1-2.0-1.7-1.7-1.91.20.6-0.20.5-0.50.30.20.3
Short access day 1 total inactive lever presses0.20.40.9-0.8-0.8-0.80.1-0.00.8-0.00.00.00.4-0.7-0.80.8-0.80.8-0.7-0.9-0.6
Short access day 10 total inactive lever presses0.00.30.6-0.7-0.7-0.70.3-0.20.7-0.2-0.2-0.20.1-0.4-0.50.7-0.50.5-0.5-0.8-0.7
Short access day 1 total infusions0.50.92.3-1.5-1.5-1.51.4-1.40.1-1.2-1.1-1.1-1.20.60.2-0.00.2-0.20.00.00.2
Short access day 10 total infusions0.71.12.4-1.3-1.3-1.31.5-1.5-0.1-1.4-1.4-1.4-1.41.00.6-0.30.6-0.60.40.10.3
Short access total infusions0.81.22.8-1.7-1.7-1.71.6-1.60.3-1.5-1.3-1.3-1.30.70.30.10.3-0.30.1-0.2-0.1
Short access day 1 locomotion0.91.55.1-1.3-1.3-1.31.6-1.7-0.9-2.3-1.4-1.4-2.01.30.6-0.40.5-0.50.40.40.5
Short access day 10 total locomotion0.21.02.3-1.3-1.3-1.31.5-1.5-0.3-1.3-1.1-1.1-1.51.00.3-0.50.3-0.30.40.50.5
Short access total locomotion0.91.34.0-2.0-2.0-2.01.7-1.60.6-1.5-0.9-0.9-1.20.3-0.40.5-0.40.4-0.5-0.3-0.2
One hour access (0.3 mA shock)1.01.23.2-0.1-0.1-0.10.9-1.0-1.5-1.8-1.1-1.1-1.71.41.2-0.91.2-1.20.90.80.7
Compulsive drug intake0.10.20.4-0.4-0.4-0.40.6-0.6-0.2-0.7-0.1-0.1-0.60.1-0.50.0-0.60.6-0.10.30.3
One hour access (shock baseline)0.20.61.5-0.2-0.2-0.20.6-0.6-0.6-0.7-0.9-0.9-0.90.91.2-0.71.2-1.20.60.40.4
Social response proportion0.60.82.01.41.41.4-1.31.3-0.01.21.01.01.2-0.60.20.00.3-0.30.0-0.0-0.0
Social responses0.81.12.51.31.31.3-1.61.6-0.20.71.51.51.2-0.9-0.30.5-0.40.4-0.6-0.4-0.5
Social time0.20.30.80.80.80.8-0.70.7-0.5-0.10.90.90.3-0.10.1-0.00.1-0.10.00.20.2
Soleus weight0.10.32.2-0.2-0.2-0.2-0.20.21.21.5-0.1-0.11.0-0.8-0.20.2-0.10.1-0.1-0.2-0.2
Bone: stiffness1.63.07.72.82.82.8-2.62.6-0.81.32.32.31.7-1.1-0.10.20.0-0.0-0.0-0.1-0.0
Tibialis anterior weight0.10.20.4-0.6-0.6-0.60.1-0.00.4-0.1-0.2-0.20.1-0.3-0.50.5-0.50.5-0.6-0.6-0.5
Time to tail flick, vehicle, before self-admin0.10.10.80.20.20.2-0.10.2-0.3-0.90.20.2-0.20.2-0.20.4-0.30.3-0.1-0.6-0.6
Time to tail flick, vehicle, after self-admin0.00.10.3-0.1-0.1-0.1-0.10.10.40.10.20.20.3-0.4-0.50.4-0.40.4-0.1-0.5-0.3
Time to tail flick, test, before self-admin0.50.61.60.00.00.0-0.50.60.4-0.30.70.70.5-0.8-0.91.1-1.01.0-0.9-1.3-1.0
Time to tail flick, test, after self-admin1.81.94.6-0.8-0.8-0.81.5-1.6-0.3-0.0-2.1-2.1-1.31.81.6-1.51.6-1.61.41.21.0
Delta time to tail flick, vehicle, before/after SA0.30.40.7-0.8-0.8-0.80.8-0.80.70.6-0.7-0.7-0.10.10.2-0.40.3-0.30.40.50.6
Delta time to tail flick, test, before/after SA3.03.76.4-0.9-0.9-0.91.9-2.1-0.8-0.3-2.5-2.5-1.92.42.3-2.32.3-2.32.22.21.8
Tibia length1.95.214.63.83.83.8-3.43.3-2.01.22.82.81.6-0.90.5-0.40.5-0.50.60.60.5
Ambulatory time before self-admin0.31.04.41.31.31.3-1.41.40.32.10.40.41.5-0.70.5-0.20.6-0.60.40.00.0
Ambulatory time after self-admin0.40.61.30.40.40.4-0.91.00.70.50.90.91.1-1.1-0.51.0-0.40.4-0.7-1.1-1.2
Bone: tissue strength0.10.10.90.30.30.3-0.30.30.41.00.20.20.6-0.20.3-0.30.4-0.40.30.30.3
Total heroin consumption0.10.10.20.40.40.4-0.40.4-0.1-0.10.50.50.2-0.2-0.30.3-0.30.3-0.4-0.0-0.4
Bone: trabecular number1.12.06.71.81.81.8-1.41.2-0.22.60.50.51.4-0.41.2-1.31.4-1.41.51.41.5
Bone: trabecular spacing0.50.71.7-0.5-0.5-0.50.10.10.2-1.20.50.5-0.2-0.3-1.11.1-1.11.1-1.3-1.2-1.3
Bone: trabecular thickness0.30.41.10.30.30.3-0.1-0.0-0.11.0-0.4-0.40.20.20.9-0.90.9-0.91.01.01.0
Bone: trabecular tissue density0.30.64.4-0.0-0.0-0.0-0.10.2-1.5-2.10.50.5-1.00.7-0.40.5-0.50.5-0.5-0.5-0.5
Water consumed over 24 hours1.22.45.3-2.2-2.2-2.22.3-2.30.3-1.0-2.3-2.3-1.71.40.6-0.60.5-0.50.50.50.5
Number of responses in last shaping day0.50.71.9-0.5-0.5-0.50.9-1.0-0.9-1.4-0.7-0.7-1.41.20.7-0.70.6-0.60.70.50.6