Hub : Genes

Spats2l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS XM_006244992.4 0.04 0.03 3.0e-04 0.04 0.03 0.03 0.03 2.1e-04 6.3e-04 1.1e-03 1.3e-03
2 Brain alternative TSS XM_006244992.4 0.03 0.02 1.6e-03 0.02 0.02 0.01 0.02 2.8e-03 4.7e-03 1.4e-02 1.1e-02
3 Brain isoform ratio XM_006244992.4 0.03 0.02 2.2e-03 0.03 0.02 0.02 0.02 1.1e-03 3.6e-03 7.0e-03 7.2e-03
4 PL isoform ratio XM_006244992.4 0.02 0.02 5.7e-03 0.01 0.02 0.02 0.02 8.0e-03 3.6e-03 4.0e-03 6.2e-03
5 Liver gene expression Spats2l 0.07 0.04 1.4e-07 0.06 0.06 0.05 0.05 8.0e-07 5.0e-07 1.2e-06 1.8e-06
6 PL gene expression Spats2l 0.04 0.03 2.7e-03 0 0.02 0.01 0.01 1.1e-01 5.8e-03 2.1e-02 1.6e-02
7 Brain isoform ratio XM_063267199.1 0.03 0.02 6.7e-03 0.02 0.01 0 0.01 5.4e-03 7.4e-02 1.0e-01 7.0e-02
8 pVTA alternative TSS XM_006244992.4 0.05 0.03 1.9e-03 0.05 0.03 0.03 0.03 1.3e-04 1.3e-03 2.3e-03 8.4e-04
9 pVTA intron excision ratio chr9_66814304_66839657 0.07 0.04 1.8e-04 0.05 0.04 0.03 0.04 1.1e-04 2.5e-04 1.7e-03 5.4e-04
10 Liver mRNA stability Spats2l 0.03 0.02 1.7e-03 0.02 0.02 0.02 0.02 3.7e-03 1.3e-03 2.9e-03 4.4e-03
11 PL alternative TSS XM_063267197.1 0.04 0.03 3.1e-03 0.01 0.01 0.02 0.01 1.4e-02 1.2e-02 3.9e-03 8.9e-03
12 pVTA alternative TSS XM_063267197.1 0.09 0.05 4.0e-05 0.07 0.07 0.07 0.07 2.8e-06 3.9e-06 2.5e-06 3.7e-06
13 pVTA intron excision ratio chr9_66814640_66839657 0.06 0.04 7.6e-04 0.04 0.04 0.04 0.04 2.2e-04 1.7e-04 3.6e-04 3.8e-04
14 pVTA alternative TSS XM_063267197.1 0.07 0.04 8.6e-04 0.05 0.05 0.04 0.04 8.8e-05 1.2e-04 5.6e-04 1.7e-04
15 pVTA isoform ratio XM_017596460.3 0.05 0.04 8.1e-03 0.03 0.01 0 0.01 3.7e-03 2.9e-02 1.8e-01 3.7e-02
16 pVTA isoform ratio XM_063267197.1 0.08 0.05 2.5e-04 0.05 0.05 0.05 0.05 5.5e-05 1.1e-04 9.5e-05 1.2e-04
17 Brain alternative TSS XM_063267197.1 0.04 0.03 6.6e-03 0.02 0.02 0.02 0.02 3.7e-03 1.1e-02 3.8e-03 7.6e-03
18 BLA gene expression Spats2l 0.17 0.08 4.7e-07 0.14 0.11 0.13 0.13 7.6e-08 1.3e-06 2.4e-07 2.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density1.01.84.4-1.6-1.6-1.6-1.00.9-0.5-2.1-0.2-0.20.9-0.0-1.5-1.5-1.61.6-1.6-1.6-1.7
Area under the delay curve0.20.30.6-0.1-0.1-0.1-0.40.40.6-0.3-0.7-0.70.60.80.50.60.5-0.50.50.50.6
BMI with tail2.68.826.05.15.15.14.4-4.23.11.63.43.4-1.9-0.60.70.90.8-0.80.81.01.0
BMI without tail0.51.66.01.91.91.91.3-1.22.5-0.61.01.00.40.80.71.00.7-0.71.01.21.0
Body weight0.10.41.4-0.9-0.9-0.9-0.90.90.4-1.2-0.5-0.51.00.6-0.30.1-0.30.30.10.50.4
Weight adjusted by age0.91.32.6-1.1-1.1-1.1-0.40.2-0.9-1.30.80.8-0.0-1.0-1.6-1.6-1.61.6-1.5-1.2-1.0
Bone surface1.73.18.3-2.9-2.9-2.9-2.52.4-0.9-2.1-1.8-1.81.70.8-0.7-0.7-0.80.8-0.9-0.8-0.9
Bone volume1.22.14.9-2.2-2.2-2.2-1.91.7-0.8-2.0-1.2-1.21.30.4-1.0-1.0-1.11.1-1.1-1.1-1.2
Breakpoint value in progressive ratio session0.20.31.0-0.7-0.7-0.7-0.40.3-0.9-0.1-0.0-0.0-0.2-0.4-0.4-0.6-0.40.4-0.4-1.0-0.6
Number of licking bursts0.30.51.0-0.2-0.2-0.20.1-0.2-1.00.20.50.5-0.6-0.9-0.9-0.9-0.90.9-0.8-0.8-0.9
Context. condit. distance diff. score0.10.10.30.50.50.50.6-0.50.20.30.20.2-0.4-0.2-0.0-0.1-0.00.00.1-0.0-0.1
Locomotion velocity, session 10.70.71.41.21.21.20.7-0.61.10.40.40.4-0.00.40.81.00.8-0.81.01.01.0
Locomotion distance, session 10.50.61.41.01.01.01.1-1.10.9-0.41.21.2-0.3-0.4-0.4-0.3-0.50.5-0.2-0.3-0.3
Locomotion velocity, session 20.40.41.50.60.60.60.2-0.11.2-0.6-0.0-0.00.60.80.70.70.7-0.70.70.70.7
Locomotion distance, session 21.31.96.91.01.01.00.10.02.6-1.4-0.2-0.21.51.81.61.61.5-1.51.51.51.5
Locomotion velocity, session 30.30.31.50.60.60.60.2-0.11.2-0.70.00.00.60.70.50.50.5-0.50.50.60.6
Locomotion distance, session 30.10.20.4-0.4-0.4-0.4-0.50.50.2-0.6-0.5-0.50.60.40.10.20.1-0.10.20.20.2
Stereotopy head waving bouts, day 30.50.61.60.80.80.81.2-1.2-0.41.30.80.8-1.3-1.0-0.3-0.3-0.20.2-0.2-0.2-0.2
Stereotopy head waving duration, day 30.60.72.01.11.11.11.4-1.40.50.51.11.1-0.8-0.7-0.4-0.4-0.30.3-0.3-0.3-0.3
Locomotion velocity, session 70.40.51.21.11.11.11.1-1.00.70.60.60.6-0.6-0.30.20.30.3-0.30.50.40.4
Locomotion distance, session 70.60.71.50.70.70.70.10.01.10.1-0.4-0.40.50.81.11.21.1-1.11.11.21.2
Stereotopy head waving bouts, day 70.70.81.5-1.2-1.2-1.2-0.80.7-0.8-1.2-0.1-0.10.4-0.1-1.0-1.0-1.01.0-1.0-1.0-1.0
Stereotopy head waving duration, day 70.40.52.0-0.3-0.3-0.3-0.10.00.2-1.40.60.60.4-0.0-0.8-0.9-0.90.9-0.9-0.9-0.9
Locomotion velocity, session 80.10.10.9-0.0-0.0-0.0-0.00.00.7-1.0-0.1-0.10.50.3-0.1-0.1-0.10.1-0.0-0.0-0.1
Locomotion distance, session 80.10.21.10.40.40.40.3-0.21.0-0.5-0.0-0.00.40.50.40.40.4-0.40.50.40.4
Degree of sensitization distance0.30.30.80.90.90.90.7-0.70.40.50.50.5-0.4-0.10.30.30.3-0.30.20.20.2
Degree of sensitization stereotypy1.21.35.4-1.5-1.5-1.5-1.51.40.2-2.3-0.8-0.81.61.0-0.4-0.4-0.50.5-0.5-0.5-0.5
Conditioned locomotion1.31.52.5-1.1-1.1-1.1-1.51.60.7-1.0-1.6-1.61.61.61.11.11.0-1.01.01.00.9
Cocaine response after cond. corrected1.21.53.1-1.7-1.7-1.7-1.81.80.1-1.2-1.7-1.71.61.20.30.30.3-0.30.30.20.2
Cocaine response after cond. not corrected1.61.94.2-2.0-2.0-2.0-1.61.4-0.9-1.6-0.9-0.91.00.1-1.1-1.2-1.21.2-1.3-1.3-1.3
Cocaine response before conditioning3.74.48.2-0.0-0.0-0.00.9-1.2-2.0-0.22.02.0-1.6-2.4-2.8-2.9-2.82.8-2.9-2.8-2.8
Saline control response0.20.30.7-0.1-0.1-0.10.1-0.1-0.3-0.40.50.5-0.1-0.5-0.8-0.8-0.80.8-0.9-0.8-0.8
Bone: connectivity density0.81.24.9-1.3-1.3-1.3-0.90.80.2-2.2-0.3-0.31.10.4-1.0-1.1-1.11.1-1.2-1.1-1.2
Bone: cortical apparent density2.63.511.62.82.82.82.3-2.1-0.13.41.41.4-2.2-1.11.11.01.2-1.21.21.21.2
Bone: cortical area0.91.43.4-1.2-1.2-1.2-1.41.4-0.91.0-1.8-1.80.40.71.11.11.1-1.11.11.11.1
Bone: cortical porosity1.82.05.6-2.4-2.4-2.4-1.91.7-1.8-0.4-1.3-1.30.5-0.2-0.9-0.7-0.90.9-0.8-0.8-0.8
Bone: cortical porosity2.62.87.6-2.8-2.8-2.8-2.11.9-2.1-0.8-1.3-1.30.6-0.3-1.3-1.1-1.31.3-1.2-1.2-1.2
Bone: cortical thickness0.91.55.00.80.80.80.3-0.2-0.22.2-0.6-0.6-0.70.11.51.51.6-1.61.61.61.6
Bone: cortical thickness0.91.12.51.31.31.31.5-1.5-0.41.51.31.3-1.6-1.1-0.2-0.3-0.10.1-0.3-0.3-0.3
Bone: cortical tissue density2.73.610.82.92.92.92.3-2.20.13.31.41.4-2.1-1.01.11.11.3-1.31.31.31.2
Condit. Reinf. active minus inactive responses1.61.74.4-1.2-1.2-1.2-0.1-0.1-2.10.50.40.4-1.1-1.5-1.7-1.6-1.71.7-1.7-1.5-1.5
Condit. Reinf. active-inactive response ratio0.60.71.4-0.6-0.6-0.60.1-0.2-1.20.40.30.3-0.8-1.0-1.1-1.0-1.11.1-1.1-0.9-0.9
Condit. Reinf. active responses1.31.63.5-1.9-1.9-1.9-1.00.8-1.9-0.2-0.4-0.4-0.3-0.8-1.3-1.3-1.31.3-1.3-1.2-1.2
Condit. Reinf. inactive responses0.40.41.0-1.0-1.0-1.0-1.01.0-0.3-0.3-0.9-0.90.60.50.20.20.2-0.20.30.20.2
Incentive salience index mean2.12.66.9-1.8-1.8-1.8-0.60.3-2.60.30.10.1-1.1-1.6-2.0-2.0-1.91.9-2.0-1.9-1.9
Condit. Reinf. lever presses0.91.33.8-1.7-1.7-1.7-0.90.7-2.00.2-0.6-0.6-0.5-0.7-1.1-1.1-1.01.0-1.2-1.2-1.2
Condit. Reinf. active minus inactive responses2.02.64.5-1.9-1.9-1.9-1.10.9-2.0-0.80.00.0-0.1-1.1-2.1-1.9-2.12.1-1.9-1.8-1.9
Condit. Reinf. active-inactive response ratio3.03.57.1-1.2-1.2-1.2-0.1-0.2-2.70.31.01.0-1.4-2.3-2.6-2.4-2.52.5-2.4-2.2-2.3
Condit. Reinf. active responses1.21.73.4-1.7-1.7-1.7-1.10.9-1.8-0.6-0.1-0.1-0.0-0.8-1.6-1.4-1.71.7-1.5-1.4-1.4
Condit. Reinf. inactive responses0.20.20.5-0.3-0.3-0.3-0.70.70.1-0.4-0.5-0.50.70.60.40.40.4-0.40.30.30.3
Condit. Reinf. lever presses2.12.96.10.40.40.41.3-1.4-2.21.51.81.8-2.3-2.5-2.0-1.9-1.91.9-1.8-1.8-1.8
Condit. Reinf. lever reinforcers received1.42.04.0-1.6-1.6-1.6-1.00.8-2.0-0.50.00.0-0.2-1.0-1.8-1.6-1.81.8-1.7-1.6-1.6
Conditioned reinforcement - actives0.10.10.70.50.50.50.4-0.4-0.20.80.10.1-0.5-0.20.10.10.2-0.20.00.3-0.0
Conditioned reinforcement - inactives0.40.63.2-0.6-0.6-0.6-0.70.7-1.31.8-0.7-0.7-0.40.30.50.70.5-0.50.60.90.5
Conditioned locomotion0.60.81.61.21.21.20.3-0.21.3-0.2-0.1-0.10.51.11.11.11.1-1.11.10.90.7
Patch foraging indifference point 0 sec0.20.41.20.60.60.60.8-0.8-0.41.10.80.8-1.0-1.0-0.5-0.3-0.40.4-0.1-0.3-0.0
Patch foraging indifference point AUC0.30.51.9-0.8-0.8-0.8-0.40.2-1.40.30.00.0-0.5-0.6-0.8-0.7-0.80.8-0.7-0.7-0.8
Delay disc. indifference point, 0s delay1.01.12.91.71.71.71.4-1.31.60.01.11.1-0.20.20.50.50.5-0.50.50.40.6
Delay disc. indifference point, 16s delay0.40.41.1-1.1-1.1-1.1-0.70.6-0.4-0.5-0.6-0.60.30.0-0.5-0.5-0.50.5-0.5-0.5-0.4
Delay disc. indifference point, 2s delay0.50.51.91.11.11.11.0-0.91.4-0.50.80.80.10.30.30.20.2-0.20.20.00.3
Delay disc. indifference point, 24s delay0.10.10.2-0.1-0.1-0.1-0.20.3-0.00.2-0.4-0.40.10.30.20.30.2-0.20.20.20.4
Delay disc. indifference point, 4s delay0.30.41.01.01.01.00.6-0.51.0-0.10.30.30.10.60.50.50.5-0.50.50.40.3
Delay disc. indifference point, 8s delay1.21.53.3-1.4-1.4-1.4-1.71.70.3-0.7-1.8-1.81.51.20.70.90.7-0.70.60.80.8
Indifference point function ln k0.10.20.90.40.40.40.10.00.9-0.2-0.1-0.10.50.50.70.50.7-0.70.60.30.5
Indifference point function log k0.10.20.90.40.40.40.10.00.9-0.2-0.1-0.10.50.50.70.50.7-0.70.60.30.5
Patch foraging total patch changes 0 sec0.61.12.30.80.80.81.2-1.3-0.71.31.31.3-1.5-1.5-0.9-0.8-0.80.8-0.6-0.7-0.5
Patch foraging total patch changes 12 sec0.50.71.80.20.20.20.6-0.7-1.21.30.80.8-1.3-1.2-0.9-0.7-0.90.9-0.7-0.4-0.4
Patch foraging total patch changes 18 sec1.31.94.91.51.51.51.9-1.9-0.82.21.71.7-2.2-1.6-0.6-0.5-0.60.6-0.4-0.5-0.3
Patch foraging total patch changes 24 sec0.40.72.2-0.4-0.4-0.40.2-0.3-1.50.60.60.6-1.0-1.0-1.0-1.1-0.90.9-0.9-1.1-1.0
Patch foraging total patch changes 6 sec0.71.02.10.20.20.20.8-0.9-0.5-0.21.21.2-0.9-1.3-1.5-1.4-1.41.4-1.2-1.1-1.0
Patch foraging time to switch 0 sec0.10.20.50.60.60.60.6-0.50.7-0.40.40.40.00.00.00.0-0.00.0-0.10.10.1
Patch foraging water rate 0 sec0.10.20.6-0.8-0.8-0.8-0.70.7-0.40.1-0.7-0.70.30.10.10.10.1-0.10.2-0.00.0
Patch foraging water rate 12 sec0.20.41.7-0.0-0.0-0.00.1-0.20.5-1.30.50.50.4-0.0-0.5-0.7-0.60.6-0.6-1.0-0.9
Patch foraging water rate 18 sec0.50.72.2-0.2-0.2-0.20.2-0.4-1.00.10.50.5-0.6-1.1-1.0-1.2-0.90.9-1.2-1.4-1.5
Patch foraging water rate 24 sec0.20.21.9-0.0-0.0-0.0-0.40.40.8-1.4-0.2-0.21.00.50.1-0.00.1-0.1-0.0-0.2-0.2
Patch foraging water rate 6 sec0.10.10.50.20.20.20.00.00.7-0.4-0.2-0.20.40.20.40.20.3-0.30.3-0.00.2
Seeking ratio, delayed vs. immediate footshock0.81.04.7-1.4-1.4-1.4-1.11.10.6-2.2-0.5-0.51.40.4-0.5-0.4-0.60.6-0.7-0.00.1
Distance traveled before self-admin0.81.02.6-1.6-1.6-1.6-1.51.4-0.7-1.3-0.3-0.30.90.3-0.8-0.6-0.90.9-0.6-0.4-0.3
Distance traveled after self-admin0.30.40.8-0.8-0.8-0.8-0.90.90.2-0.6-0.5-0.50.80.4-0.20.4-0.30.30.20.80.7
Extensor digitorum longus weight1.03.88.22.92.92.91.6-1.32.60.60.90.90.11.02.02.02.0-2.02.12.22.2
Bone: elastic displacement1.31.52.40.70.70.71.3-1.4-0.50.21.51.5-1.3-1.4-1.3-1.4-1.31.3-1.4-1.4-1.4
Bone: elastic work0.10.20.3-0.1-0.1-0.10.1-0.2-0.50.10.20.2-0.3-0.5-0.5-0.6-0.50.5-0.6-0.6-0.5
Bone: endosteal estimation1.32.87.2-2.7-2.7-2.7-2.01.8-2.1-0.9-1.2-1.20.5-0.4-1.4-1.3-1.51.5-1.4-1.4-1.4
Bone: endosteal perimeter1.22.67.4-2.7-2.7-2.7-2.22.0-1.2-1.5-1.5-1.51.20.4-1.0-0.9-1.01.0-0.9-0.9-1.0
Epididymis fat weight0.82.75.0-1.0-1.0-1.0-1.81.91.4-1.3-1.7-1.72.22.21.51.81.4-1.41.51.91.9
Delta time in closed arm before/after self-admin0.00.00.2-0.2-0.2-0.2-0.20.1-0.40.0-0.0-0.0-0.1-0.1-0.1-0.1-0.20.2-0.2-0.3-0.1
Delta time in open arm before/after self-admin2.32.26.3-2.5-2.5-2.5-1.91.7-2.1-0.8-0.6-0.60.5-0.3-1.2-1.2-1.21.2-0.9-1.0-0.9
Diff in mean of infusions in LGA sessions1.72.14.7-0.4-0.4-0.40.4-0.6-1.1-0.91.31.3-0.7-1.6-1.9-2.2-1.81.8-2.0-2.1-2.1
Delay discount exponential model param0.20.20.50.30.30.30.4-0.5-0.50.40.70.7-0.6-0.7-0.4-0.4-0.30.3-0.3-0.3-0.4
Extinction: sum of active levers before priming0.10.10.3-0.3-0.3-0.3-0.20.1-0.4-0.40.00.00.0-0.4-0.2-0.5-0.10.1-0.4-0.5-0.5
Active lever presses in extinction session 60.40.40.8-0.6-0.6-0.6-0.80.9-0.10.0-0.8-0.80.60.40.50.60.5-0.50.60.50.6
Bone: final force0.71.22.9-1.6-1.6-1.6-1.61.6-1.10.1-1.7-1.70.60.50.30.40.3-0.30.30.30.3
Bone: final moment0.30.51.2-1.1-1.1-1.1-1.01.0-1.00.3-1.0-1.00.20.0-0.00.10.0-0.00.10.00.1
Food consumed during 24 hour testing period0.81.13.01.71.71.71.6-1.50.51.01.31.3-1.0-0.70.10.10.2-0.20.20.20.2
Glucose0.60.92.91.71.71.71.3-1.31.20.11.11.1-0.4-0.10.30.30.3-0.30.20.40.4
Heart weight1.01.53.4-1.9-1.9-1.9-1.21.1-0.8-1.7-0.6-0.60.8-0.1-1.0-1.2-1.11.1-1.3-1.1-1.3
Delay discount hyperbolic model param0.30.30.80.10.10.10.4-0.5-0.70.50.70.7-0.7-0.9-0.6-0.6-0.50.5-0.5-0.4-0.5
Intermittent access intake day 1-15 change0.81.63.11.21.21.21.6-1.6-0.40.61.81.8-1.4-1.5-1.0-1.2-1.01.0-1.1-1.1-1.0
Intermittent access intake escalation1.12.24.41.51.51.51.9-2.0-0.50.82.12.1-1.7-1.8-1.2-1.3-1.11.1-1.2-1.2-1.2
Intermittent access intake escalation 21.11.32.40.30.30.30.7-0.9-0.8-0.21.51.5-0.9-1.4-1.4-1.5-1.41.4-1.3-1.4-1.4
Intermitt. access day 1 inactive lever presses0.93.58.93.03.03.02.8-2.70.32.71.81.8-2.3-1.2-0.10.20.1-0.10.10.00.1
Intermitt. access day 15 inactive lever presses0.51.02.11.21.21.21.3-1.3-0.50.81.41.4-1.3-0.9-0.7-0.7-0.70.7-0.6-0.9-0.8
Intermitt. access escalation Index1.01.44.20.40.40.4-0.20.41.01.2-1.3-1.30.41.01.11.81.1-1.11.42.12.0
Intermittent access day 1 total infusions0.30.41.4-0.1-0.1-0.10.3-0.4-0.81.20.60.6-0.9-0.7-0.9-0.3-0.90.9-0.40.2-0.0
Intermittent access day 15 total infusions1.32.04.21.41.41.41.8-1.9-0.81.91.81.8-2.1-1.7-1.1-0.9-1.11.1-1.0-0.5-0.7
Intermittent access terminal intake (last 3 days)2.12.75.01.61.61.62.1-2.1-0.91.72.12.1-2.2-2.0-1.4-1.2-1.41.4-1.3-1.0-1.2
Intermittent access total infusions1.11.32.71.01.01.01.3-1.4-0.71.51.51.5-1.6-1.3-1.2-0.7-1.21.2-0.8-0.4-0.5
Intermittent access day 1 locomotion0.40.53.00.50.50.50.7-0.7-0.81.70.60.6-1.2-0.6-0.4-0.1-0.40.4-0.00.20.1
Intermittent access day 15 total locomotion0.40.71.40.70.70.70.9-1.0-0.71.01.21.2-1.1-0.8-0.9-0.7-0.90.9-0.5-0.5-0.6
Intermittent access total locomotion0.40.41.11.11.11.11.0-0.90.00.90.80.8-0.8-0.2-0.20.0-0.20.20.1-0.1-0.0
Intermittent access standard deviation1.32.85.40.80.80.81.7-1.9-1.11.32.22.2-2.1-2.3-1.9-1.7-1.91.9-1.8-1.2-1.3
Left kidney weight0.10.30.90.10.10.10.3-0.30.6-1.00.90.90.2-0.2-0.8-0.5-0.90.9-0.80.1-0.2
Right kidney weight0.20.95.2-0.4-0.4-0.4-0.60.71.9-2.3-0.4-0.41.71.30.10.40.0-0.00.20.80.7
Cocaine induced anxiety0.71.02.00.20.20.2-0.60.71.1-0.4-0.9-0.91.01.41.31.31.2-1.21.21.21.2
Post-drug Anxiety0.40.51.60.00.00.0-0.40.41.3-1.1-0.4-0.41.11.00.60.70.6-0.60.50.70.6
Baseline Anxiety0.70.81.7-0.7-0.7-0.70.0-0.2-0.2-1.00.80.8-0.0-0.9-1.3-1.1-1.31.3-1.2-0.8-0.8
Tail length3.312.932.5-5.7-5.7-5.7-5.65.4-1.5-3.3-4.4-4.43.72.4-0.10.3-0.30.30.20.70.4
Length with tail2.912.536.9-6.1-6.1-6.1-5.35.0-2.7-3.0-3.7-3.72.91.1-1.3-0.9-1.41.4-1.0-0.6-0.7
Length without tail1.13.510.1-3.2-3.2-3.2-2.32.2-2.0-1.4-1.3-1.30.9-0.2-1.4-1.4-1.51.5-1.3-1.3-1.2
Times rat made contact with spout1.01.13.21.81.81.81.2-1.11.10.60.90.9-0.4-0.00.80.80.8-0.80.80.80.8
Lifetime Intake1.01.32.41.31.31.31.5-1.5-0.21.41.51.5-1.5-1.1-0.9-0.4-0.90.9-0.6-0.2-0.3
Liver weight, left1.01.73.4-1.7-1.7-1.7-1.81.80.3-1.3-1.8-1.81.71.20.60.60.5-0.50.30.60.6
Liver weight, right1.32.24.6-1.1-1.1-1.1-0.30.1-1.2-1.30.90.9-0.2-1.1-2.1-2.1-2.12.1-2.1-2.0-2.1
Locomotor activity0.20.30.70.80.80.80.5-0.40.80.30.20.2-0.00.30.40.60.5-0.50.80.70.8
Locomotor testing distance0.61.02.41.41.41.41.5-1.50.50.51.61.6-0.9-0.6-0.5-0.3-0.50.50.0-0.30.0
Locomotor testing rearing0.10.10.40.50.50.50.2-0.10.40.00.20.20.20.40.20.40.2-0.20.60.20.4
Locomotion in novel chamber5.77.315.11.61.61.63.0-3.2-1.00.83.93.9-2.9-3.4-2.9-2.9-2.82.8-2.9-2.4-2.4
Locomotion in novel chamber post-restriction1.21.93.6-0.2-0.2-0.20.6-0.8-1.61.01.61.6-1.5-1.9-1.9-1.6-1.81.8-1.5-1.5-1.4
Fecal boli incidents, locomotor time 10.30.40.8-0.8-0.8-0.8-0.40.4-0.8-0.5-0.2-0.2-0.1-0.2-0.8-0.9-0.90.9-0.5-0.8-0.8
Change in fecal boli incidents, locomotor task0.30.30.80.60.60.60.3-0.20.60.6-0.2-0.20.00.30.70.70.7-0.70.50.50.9
Time >=10cm from walls, locomotor time 10.40.41.1-0.4-0.4-0.4-0.60.7-0.30.5-1.1-1.10.20.50.50.70.5-0.50.80.80.6
Bouts of movement, locomotor time 11.41.55.6-0.7-0.7-0.70.3-0.5-2.42.00.20.2-1.8-1.8-1.3-1.2-1.21.2-1.2-1.0-1.1
Total resting periods, locomotor time 11.41.57.2-0.1-0.1-0.10.9-1.0-2.12.70.50.5-2.2-1.9-1.0-0.9-0.80.8-0.8-0.6-0.7
Rest time, locomotor task time 11.21.58.30.30.30.30.3-0.2-0.52.9-1.0-1.0-1.10.01.21.41.4-1.41.41.91.7
Distance moved, locomotor task time 11.11.66.5-1.4-1.4-1.4-1.91.90.4-2.5-1.0-1.02.11.30.00.1-0.10.10.2-0.3-0.2
Vertical activity count, locomotor time 10.30.63.0-0.6-0.6-0.6-1.11.10.6-1.7-0.5-0.51.51.00.20.30.1-0.10.4-0.10.0
Time >=10cm from walls, locomotor time 20.81.23.00.60.60.6-0.30.41.7-0.9-0.6-0.61.31.51.21.31.1-1.11.51.21.3
Bouts of movement, locomotor time 20.10.10.3-0.2-0.2-0.20.2-0.3-0.0-0.00.20.2-0.2-0.5-0.3-0.4-0.20.2-0.4-0.4-0.4
Total resting periods, locomotor time 20.10.20.8-0.1-0.1-0.10.4-0.5-0.50.60.40.4-0.7-0.9-0.4-0.6-0.40.4-0.5-0.5-0.5
Rest time, locomotor task time 20.81.07.70.40.40.40.5-0.5-1.02.8-0.6-0.6-1.4-0.60.80.70.9-0.90.81.10.8
Distance moved, locomotor task time 20.30.32.0-0.3-0.3-0.3-0.70.70.7-1.4-0.2-0.21.20.5-0.2-0.0-0.30.3-0.1-0.1-0.1
Vertical activity count, locomotor time 20.60.83.91.31.31.30.9-0.72.0-0.90.80.80.60.60.20.40.1-0.10.60.60.4
Light reinforcement 11.84.311.03.33.33.32.1-1.82.80.80.90.9-0.21.01.91.91.9-1.92.01.81.9
Light reinforcement 20.30.40.9-0.2-0.2-0.2-0.60.60.9-0.8-0.9-0.91.00.90.60.70.5-0.50.40.70.6
Bone: marrow area1.32.77.0-2.6-2.6-2.6-1.91.7-2.1-0.8-1.2-1.20.5-0.4-1.4-1.3-1.41.4-1.3-1.4-1.4
Bone: maximum diameter1.22.25.2-2.3-2.3-2.3-2.22.2-1.60.3-2.3-2.30.80.60.40.50.4-0.40.40.40.4
Bone: maximum force0.51.02.8-1.7-1.7-1.7-1.41.3-0.9-0.5-1.2-1.20.60.2-0.3-0.2-0.30.3-0.3-0.3-0.3
Bone: maximum moment0.20.41.0-1.0-1.0-1.0-0.70.6-0.8-0.3-0.4-0.40.1-0.2-0.6-0.5-0.60.6-0.5-0.6-0.5
Mean time between licks in bursts1.33.26.30.90.90.9-0.20.42.10.1-1.1-1.11.21.92.42.42.4-2.42.52.52.5
Mean num. licks in bursts1.01.63.11.51.51.50.8-0.61.80.5-0.0-0.00.30.91.61.51.6-1.61.61.51.5
Cd content in liver0.00.00.10.00.00.0-0.00.00.4-0.2-0.2-0.20.20.20.10.20.1-0.10.10.10.2
Co content in liver0.60.61.40.20.20.20.6-0.7-1.11.00.60.6-1.2-1.2-0.8-0.9-0.80.8-0.7-1.0-0.8
Cu content in liver0.10.20.4-0.5-0.5-0.5-0.60.6-0.2-0.2-0.6-0.60.40.40.20.30.2-0.20.30.20.2
Fe content in liver1.82.24.4-1.0-1.0-1.00.1-0.3-1.3-0.60.80.8-0.6-1.4-2.1-2.1-2.12.1-2.1-2.1-2.1
K content in liver0.80.81.7-0.9-0.9-0.9-1.21.2-0.2-0.1-1.3-1.30.80.80.70.70.7-0.70.70.60.7
Mg content in liver0.10.10.5-0.7-0.7-0.7-0.40.4-0.4-0.1-0.3-0.30.1-0.1-0.2-0.2-0.20.2-0.2-0.3-0.3
Mn content in liver1.41.65.81.51.51.51.8-1.8-0.42.41.11.1-1.9-1.30.20.10.3-0.30.30.30.4
Na content in liver0.80.92.4-1.5-1.5-1.5-1.41.4-0.8-0.4-1.3-1.30.70.50.10.10.0-0.00.1-0.3-0.1
Rb content in liver0.80.92.4-0.9-0.9-0.9-1.11.21.0-1.4-1.2-1.21.51.30.60.60.5-0.50.50.40.5
Se content in liver0.00.00.1-0.3-0.3-0.3-0.30.2-0.2-0.1-0.2-0.20.10.1-0.0-0.0-0.00.00.0-0.0-0.1
Sr content in liver0.70.61.40.40.40.4-0.10.20.21.1-0.7-0.7-0.00.51.11.21.1-1.11.11.11.2
Zn content in liver0.30.40.7-0.1-0.1-0.1-0.30.40.30.3-0.6-0.60.30.60.80.80.8-0.80.90.80.8
Bone: minimum diameter0.51.02.6-1.6-1.6-1.6-1.31.3-1.50.6-1.3-1.30.10.00.10.10.1-0.10.10.10.1
Time in familiar zone, hab. session 11.51.53.3-0.5-0.5-0.50.3-0.5-0.4-1.10.90.9-0.3-1.1-1.7-1.8-1.81.8-1.7-1.8-1.8
Time in novel zone, hab. session 11.11.12.30.20.20.2-0.40.50.20.9-0.9-0.90.20.91.51.51.5-1.51.41.51.5
Total zone transitions, hab. session 10.20.31.2-0.8-0.8-0.8-0.60.5-0.1-1.1-0.0-0.00.60.1-0.5-0.5-0.60.6-0.4-0.6-0.5
Total locomotion distance, hab. session 11.11.52.8-1.2-1.2-1.2-0.40.2-1.7-0.10.40.4-0.6-1.2-1.7-1.6-1.71.7-1.6-1.6-1.6
Locomotion velocity, hab. session 10.71.02.1-1.1-1.1-1.1-0.50.3-1.50.00.20.2-0.4-1.0-1.3-1.2-1.21.2-1.2-1.2-1.2
Time in familiar zone, hab. session 21.41.52.90.70.70.71.2-1.3-1.31.21.51.5-1.7-1.7-1.2-1.2-1.11.1-1.2-1.2-1.2
Time in novel zone, hab. session 21.01.02.10.30.30.3-0.30.51.5-0.5-0.7-0.71.11.31.31.31.3-1.31.31.31.3
Total zone transitions, hab. session 20.40.51.91.11.11.10.7-0.61.4-0.70.60.60.40.50.50.40.4-0.40.50.40.4
Total locomotion distance, hab. session 20.30.31.30.90.90.90.6-0.61.2-0.60.70.70.30.30.20.20.2-0.20.30.20.2
Locomotion velocity, hab. session 20.20.31.20.90.90.90.5-0.51.1-0.50.50.50.30.30.30.40.3-0.30.40.30.3
Novel to familiar place preference ratio0.20.21.00.50.50.50.2-0.11.0-0.70.20.20.50.60.40.40.4-0.40.40.40.3
Novelty place preference0.10.20.70.50.50.50.2-0.20.9-0.60.30.30.40.40.30.20.2-0.20.20.20.2
Time in novel zone, NPP test0.20.20.80.60.60.60.4-0.30.9-0.70.50.50.30.30.10.10.0-0.00.00.00.0
Total zone transitions, NPP test0.10.10.2-0.0-0.0-0.00.1-0.1-0.0-0.40.40.4-0.0-0.2-0.4-0.4-0.40.4-0.3-0.4-0.4
Total locomotion distance, NPP test1.11.52.70.40.40.41.1-1.3-0.70.21.61.6-1.2-1.6-1.5-1.4-1.51.5-1.3-1.4-1.4
Locomotion velocity, NPP test1.01.32.50.60.60.61.2-1.3-0.70.61.61.6-1.3-1.6-1.3-1.2-1.21.2-1.1-1.1-1.1
Intraocular pressure2.02.86.72.62.62.62.6-2.50.51.92.02.0-1.9-1.3-0.3-0.1-0.20.20.10.00.1
Delta distance traveled before/after self-admin0.40.41.10.90.90.90.6-0.50.80.7-0.0-0.0-0.20.10.40.80.4-0.40.71.10.9
Delta ambulatory time before/after self-admin0.91.12.70.90.90.90.3-0.10.91.2-0.7-0.70.00.71.21.51.2-1.21.51.61.5
Parametrial fat weight1.02.45.61.11.11.10.20.11.60.7-0.7-0.70.61.42.02.22.0-2.02.22.42.3
Pavlov. Cond. lever latency1.01.22.51.21.21.20.6-0.41.50.4-0.1-0.10.20.81.41.41.4-1.41.61.51.5
Pavlov. Cond. magazine entry latency1.92.55.2-1.1-1.1-1.1-0.1-0.1-2.30.20.70.7-1.1-1.8-2.1-2.1-2.12.1-2.2-2.0-2.0
Pavlov. Cond. change in total contacts1.92.04.2-1.0-1.0-1.0-0.1-0.2-1.7-0.20.70.7-0.9-1.4-1.9-1.9-1.91.9-2.0-1.9-1.9
Pavlov. Cond. index score2.12.66.1-1.3-1.3-1.3-0.40.1-2.50.20.40.4-1.0-1.7-2.1-2.1-2.02.0-2.3-2.1-2.1
Pavlov. Cond. latency score2.22.85.9-1.5-1.5-1.5-0.50.2-2.4-0.10.40.4-0.8-1.6-2.2-2.2-2.22.2-2.4-2.2-2.2
Pavlov. Cond. lever contacts1.21.53.3-0.9-0.9-0.9-0.1-0.0-1.7-0.00.40.4-0.7-1.2-1.6-1.7-1.51.5-1.8-1.7-1.7
Pavlov. Cond. magazine entry number1.51.94.01.21.21.20.3-0.11.90.1-0.4-0.40.71.41.91.81.8-1.82.01.81.8
Pavlov. Cond. intertrial magazine entries0.40.51.0-0.9-0.9-0.9-0.80.90.4-1.0-0.8-0.80.90.90.30.30.3-0.30.30.40.3
Pavlov. Cond. lever-magazine prob. diff.2.12.56.1-1.2-1.2-1.2-0.1-0.1-2.50.50.60.6-1.2-1.8-2.0-2.1-2.02.0-2.2-2.1-2.0
Pavlov. Cond. response bias1.62.05.2-1.3-1.3-1.3-0.50.2-2.30.30.10.1-0.9-1.4-1.8-1.8-1.71.7-2.0-1.7-1.7
Pavlov. Cond. lever latency1.82.45.8-0.5-0.5-0.5-1.21.42.1-1.9-1.5-1.52.32.41.61.51.5-1.51.41.41.4
Pavlov. Cond. magazine entry latency0.60.82.20.40.40.40.8-0.9-1.21.50.90.9-1.5-1.4-0.7-0.6-0.70.7-0.5-0.5-0.5
Pavlov. Cond. change in total contacts0.91.57.7-1.1-1.1-1.1-0.40.2-2.81.7-0.1-0.1-1.4-1.6-1.2-1.0-1.11.1-1.0-0.9-0.9
Pavlov. Cond. index score1.11.55.3-0.1-0.1-0.10.6-0.7-2.32.00.80.8-2.0-2.0-1.2-1.1-1.11.1-1.0-1.0-0.9
Pavlov. Cond. latency score1.11.55.1-0.0-0.0-0.00.6-0.8-2.32.00.80.8-2.0-2.0-1.2-1.1-1.11.1-1.0-0.9-0.9
Pavlov. Cond. lever contacts2.23.17.30.20.20.21.1-1.3-2.62.01.61.6-2.4-2.7-2.0-1.9-1.91.9-1.8-1.8-1.7
Pavlov. Cond. magazine entry number0.50.62.40.00.00.0-0.40.51.5-1.5-0.4-0.41.31.20.70.50.6-0.60.40.30.4
Pavlov. Cond. intertrial magazine entries0.30.42.20.00.00.00.1-0.20.7-1.50.70.70.50.1-0.6-0.6-0.70.7-0.7-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.1.01.35.2-0.1-0.1-0.10.5-0.6-2.32.00.70.7-1.9-1.8-1.1-1.0-1.01.0-0.9-0.8-0.8
Pavlov. Cond. response bias1.52.14.80.10.10.10.9-1.0-2.21.61.31.3-2.0-2.2-1.6-1.5-1.61.6-1.4-1.4-1.4
Time in closed arm before self-admin0.70.92.8-1.7-1.7-1.7-1.11.0-1.1-0.4-0.6-0.60.2-0.2-0.7-0.6-0.80.8-0.8-0.3-0.7
Time in closed arm after self-admin0.50.61.1-1.1-1.1-1.1-0.80.7-0.6-0.9-0.1-0.10.4-0.0-0.8-0.7-0.90.9-0.9-0.4-0.9
Time in open arm before self-admin3.03.38.22.92.92.91.9-1.71.81.70.50.5-0.70.31.61.71.7-1.71.81.61.7
Time in open arm after self-admin0.40.42.0-0.8-0.8-0.8-0.50.4-1.40.6-0.2-0.2-0.5-0.8-0.7-0.6-0.50.5-0.2-0.4-0.3
Bone: periosteal estimation1.22.47.0-2.7-2.7-2.7-2.32.1-2.0-0.1-2.0-2.00.60.2-0.4-0.3-0.40.4-0.3-0.3-0.3
Bone: periosteal perimeter0.81.44.2-2.1-2.1-2.1-1.61.6-1.4-0.4-1.4-1.40.60.1-0.5-0.4-0.50.5-0.4-0.4-0.4
Bone: post-yield work0.30.50.90.30.30.30.7-0.8-0.0-0.10.90.9-0.5-0.8-0.9-0.8-0.80.8-0.7-0.7-0.8
Progressive ratio test 1 active lever presses1.61.94.41.11.11.11.7-1.7-1.02.11.71.7-2.1-1.6-1.2-0.8-1.21.2-0.9-0.6-0.6
Progressive ratio test 1 breakpoint1.41.73.70.90.90.91.5-1.5-1.01.81.61.6-1.9-1.6-1.3-0.9-1.31.3-1.0-0.7-0.7
Progressive ratio test 1 inactive lever presses2.43.48.83.03.03.02.7-2.60.92.71.81.8-2.0-0.70.20.70.2-0.20.50.90.7
Progressive ratio test 2 active lever presses0.91.14.40.60.60.61.0-1.1-1.22.11.01.0-1.7-1.3-0.9-0.6-0.90.9-0.7-0.2-0.5
Progressive ratio test 2 breakpoint1.01.24.20.70.70.71.1-1.1-1.22.01.11.1-1.8-1.4-1.0-0.6-0.90.9-0.7-0.2-0.5
Progressive ratio test 2 inactive lever presses0.81.35.51.41.41.41.4-1.4-0.82.41.31.3-1.8-1.0-0.5-0.1-0.50.5-0.00.0-0.2
Incentive Sensitization - Responses0.20.30.8-0.6-0.6-0.6-0.70.7-0.90.9-0.6-0.6-0.10.00.20.30.2-0.20.20.60.2
Incentive Sensitization - Breakpoint0.20.30.8-0.5-0.5-0.5-0.70.7-0.80.9-0.7-0.7-0.00.20.30.40.3-0.30.40.70.4
Sum of active levers in priming session hrs 5-61.91.73.3-1.0-1.0-1.0-1.51.60.2-0.4-1.8-1.81.31.61.51.21.4-1.41.60.91.0
Progressive ratio0.40.72.20.50.50.50.2-0.00.71.2-0.4-0.4-0.00.40.91.31.0-1.01.01.31.5
Food seeking constrained by brief footshock0.70.92.1-0.4-0.4-0.40.1-0.3-0.8-0.20.70.7-0.4-1.2-1.4-1.3-1.41.4-1.2-1.2-1.5
Seeking ratio, punishment vs. effort1.11.74.5-1.4-1.4-1.4-0.90.7-0.8-2.1-0.1-0.10.7-0.3-1.3-1.7-1.31.3-1.3-1.9-1.9
Retroperitoneal fat weight0.62.55.40.90.90.9-0.00.32.1-0.0-0.8-0.81.11.72.02.22.0-2.02.22.32.3
Reaction time number correct0.40.81.60.80.80.81.1-1.10.2-0.21.31.3-0.6-0.9-0.8-0.8-0.80.8-0.7-0.8-0.9
Reaction time mean minus median0.00.00.0-0.1-0.1-0.1-0.10.1-0.1-0.00.00.00.10.20.0-0.00.0-0.00.10.1-0.1
Reaction time mean minus median AUC0.20.61.00.20.20.20.6-0.7-0.90.60.80.8-1.0-1.0-0.8-0.9-0.80.8-0.7-0.8-0.9
Reaction time num false alarms1.21.63.41.51.51.50.9-0.71.90.6-0.0-0.00.20.81.31.51.4-1.41.51.81.7
Reaction time num false alarms AUC1.21.94.21.61.61.60.9-0.62.00.4-0.1-0.10.30.91.41.61.5-1.51.62.01.8
Reaction time trials correct on left0.40.81.60.80.80.81.1-1.10.2-0.21.31.3-0.6-0.9-0.8-0.8-0.80.8-0.7-0.8-0.9
Reaction time trials on left0.40.71.50.80.80.81.0-1.10.2-0.31.21.2-0.6-0.9-0.8-0.8-0.80.8-0.7-0.8-0.8
Reaction time mean1.32.04.1-1.9-1.9-1.9-2.02.0-0.70.3-2.0-2.01.01.10.91.00.9-0.91.01.31.1
Reaction time mean AUC1.11.73.5-1.5-1.5-1.5-1.71.7-0.60.4-1.9-1.90.91.11.01.10.9-0.91.11.31.1
Median of all reaction times2.23.26.8-2.3-2.3-2.3-2.42.5-0.90.5-2.6-2.61.21.31.11.31.1-1.11.21.61.4
Reaction time omissions0.20.20.7-0.3-0.3-0.3-0.50.60.5-0.7-0.4-0.40.80.80.40.40.2-0.20.50.40.4
Reaction time false alarm rate1.31.74.40.90.90.90.10.11.60.5-0.8-0.80.61.31.61.81.7-1.71.72.12.0
Reaction time premature initiation rate1.52.14.30.40.40.41.1-1.3-1.51.01.61.6-1.8-2.1-1.6-1.7-1.51.5-1.6-1.7-1.6
Reaction time premature initiations1.62.95.30.90.90.91.7-1.8-1.20.82.12.1-1.9-2.3-1.8-1.9-1.71.7-1.8-1.9-1.9
Std. dev. reaction times0.30.51.3-1.1-1.1-1.1-1.11.1-0.5-0.5-0.7-0.70.60.50.0-0.0-0.00.00.20.20.0
Reaction time trials completed0.40.71.50.80.80.81.0-1.10.2-0.31.21.2-0.6-0.9-0.8-0.8-0.80.8-0.7-0.8-0.8
Reaction time trials AUC0.30.61.20.70.70.70.9-1.00.2-0.21.11.1-0.5-0.8-0.7-0.7-0.70.7-0.6-0.7-0.7
Run reversals in cocaine runway, females0.00.00.10.10.10.10.1-0.1-0.10.1-0.1-0.1-0.10.10.10.10.1-0.10.30.10.0
Run reversals in cocaine runway, males0.80.81.9-0.5-0.5-0.50.4-0.5-1.40.80.70.7-1.2-1.3-1.1-1.1-1.01.0-1.0-0.8-0.9
Latency to leave start box in cocaine runway2.02.26.72.62.62.62.1-2.01.41.31.31.3-1.0-0.20.70.70.7-0.70.80.70.6
Latency to leave start box in cocaine runway, F1.71.95.02.22.22.21.3-1.11.41.00.40.4-0.30.71.41.41.4-1.41.61.00.9
Latency to leave start box in cocaine runway, M2.32.25.01.41.41.42.1-2.20.40.62.22.2-1.5-1.6-1.3-1.1-1.21.2-1.2-0.6-0.7
Std. dev. time between licks in bursts0.60.71.91.41.41.41.0-0.90.80.70.70.7-0.4-0.10.60.70.7-0.70.70.80.8
Total sessions with >9 infusions1.72.14.62.02.02.02.1-2.1-0.12.01.71.7-1.9-1.2-0.6-0.2-0.50.5-0.3-0.2-0.3
Short access day 1 total inactive lever presses0.30.40.90.80.80.80.1-0.00.80.0-0.0-0.00.40.70.80.80.8-0.80.70.90.6
Short access day 10 total inactive lever presses0.10.30.60.70.70.70.3-0.20.70.20.20.20.10.40.50.70.5-0.50.50.80.7
Short access day 1 total infusions0.70.92.31.51.51.51.4-1.40.11.21.11.1-1.2-0.6-0.2-0.0-0.20.2-0.0-0.0-0.2
Short access day 10 total infusions0.91.12.41.31.31.31.5-1.5-0.11.41.41.4-1.4-1.0-0.6-0.3-0.60.6-0.4-0.1-0.3
Short access total infusions0.91.22.81.71.71.71.6-1.60.31.51.31.3-1.3-0.7-0.30.1-0.30.3-0.10.20.1
Short access day 1 locomotion1.21.55.11.31.31.31.6-1.7-0.92.31.41.4-2.0-1.3-0.6-0.4-0.50.5-0.4-0.4-0.5
Short access day 10 total locomotion0.51.02.31.31.31.31.5-1.5-0.31.31.11.1-1.5-1.0-0.3-0.5-0.30.3-0.4-0.5-0.5
Short access total locomotion1.11.34.02.02.02.01.7-1.60.61.50.90.9-1.2-0.30.40.50.4-0.40.50.30.2
One hour access (0.3 mA shock)1.11.23.20.10.10.10.9-1.0-1.51.81.11.1-1.7-1.4-1.2-0.9-1.21.2-0.9-0.8-0.7
Compulsive drug intake0.10.20.40.40.40.40.6-0.6-0.20.70.10.1-0.6-0.10.50.00.6-0.60.1-0.3-0.3
One hour access (shock baseline)0.40.61.50.20.20.20.6-0.6-0.60.70.90.9-0.9-0.9-1.2-0.7-1.21.2-0.6-0.4-0.4
Social response proportion0.70.82.0-1.4-1.4-1.4-1.31.3-0.0-1.2-1.0-1.01.20.6-0.20.0-0.30.3-0.00.00.0
Social responses0.81.12.5-1.3-1.3-1.3-1.61.6-0.2-0.7-1.5-1.51.20.90.30.50.4-0.40.60.40.5
Social time0.20.30.8-0.8-0.8-0.8-0.70.7-0.50.1-0.9-0.90.30.1-0.1-0.0-0.10.1-0.0-0.2-0.2
Soleus weight0.10.32.20.20.20.2-0.20.21.2-1.50.10.11.00.80.20.20.1-0.10.10.20.2
Bone: stiffness1.83.07.7-2.8-2.8-2.8-2.62.6-0.8-1.3-2.3-2.31.71.10.10.2-0.00.00.00.10.0
Tibialis anterior weight0.10.20.40.60.60.60.1-0.00.40.10.20.20.10.30.50.50.5-0.50.60.60.5
Time to tail flick, vehicle, before self-admin0.10.10.8-0.2-0.2-0.2-0.10.2-0.30.9-0.2-0.2-0.2-0.20.20.40.3-0.30.10.60.6
Time to tail flick, vehicle, after self-admin0.10.10.30.10.10.1-0.10.10.4-0.1-0.2-0.20.30.40.50.40.4-0.40.10.50.3
Time to tail flick, test, before self-admin0.50.61.6-0.0-0.0-0.0-0.50.60.40.3-0.7-0.70.50.80.91.11.0-1.00.91.31.0
Time to tail flick, test, after self-admin1.91.94.60.80.80.81.5-1.6-0.30.02.12.1-1.3-1.8-1.6-1.5-1.61.6-1.4-1.2-1.0
Delta time to tail flick, vehicle, before/after SA0.40.40.70.80.80.80.8-0.80.7-0.60.70.7-0.1-0.1-0.2-0.4-0.30.3-0.4-0.5-0.6
Delta time to tail flick, test, before/after SA3.63.76.40.90.90.91.9-2.1-0.80.32.52.5-1.9-2.4-2.3-2.3-2.32.3-2.2-2.2-1.8
Tibia length1.95.214.6-3.8-3.8-3.8-3.43.3-2.0-1.2-2.8-2.81.60.9-0.5-0.4-0.50.5-0.6-0.6-0.5
Ambulatory time before self-admin0.71.04.4-1.3-1.3-1.3-1.41.40.3-2.1-0.4-0.41.50.7-0.5-0.2-0.60.6-0.4-0.0-0.0
Ambulatory time after self-admin0.50.61.3-0.4-0.4-0.4-0.91.00.7-0.5-0.9-0.91.11.10.51.00.4-0.40.71.11.2
Bone: tissue strength0.10.10.9-0.3-0.3-0.3-0.30.30.4-1.0-0.2-0.20.60.2-0.3-0.3-0.40.4-0.3-0.3-0.3
Total heroin consumption0.10.10.2-0.4-0.4-0.4-0.40.4-0.10.1-0.5-0.50.20.20.30.30.3-0.30.40.00.4
Bone: trabecular number1.22.06.7-1.8-1.8-1.8-1.41.2-0.2-2.6-0.5-0.51.40.4-1.2-1.3-1.41.4-1.5-1.4-1.5
Bone: trabecular spacing0.50.71.70.50.50.50.10.10.21.2-0.5-0.5-0.20.31.11.11.1-1.11.31.21.3
Bone: trabecular thickness0.40.41.1-0.3-0.3-0.3-0.1-0.0-0.1-1.00.40.40.2-0.2-0.9-0.9-0.90.9-1.0-1.0-1.0
Bone: trabecular tissue density0.40.64.40.00.00.0-0.10.2-1.52.1-0.5-0.5-1.0-0.70.40.50.5-0.50.50.50.5
Water consumed over 24 hours1.82.45.32.22.22.22.3-2.30.31.02.32.3-1.7-1.4-0.6-0.6-0.50.5-0.5-0.5-0.5
Number of responses in last shaping day0.60.71.90.50.50.50.9-1.0-0.91.40.70.7-1.4-1.2-0.7-0.7-0.60.6-0.7-0.5-0.6