Hub : Genes

Spata31g1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	Spata31g1	0.08	0.05	6.6e-06	0.06	0.05	0.06	0.05	5.7e-06	1.4e-05	6.7e-06	1.8e-05
2	Adipose	gene expression	Spata31g1	0.28	0.12	0.0e+00	0.22	0.23	0.23	0.23	3.5e-24	3.2e-25	2.0e-25	9.3e-26
3	PL	gene expression	Spata31g1	0.05	0.04	3.4e-04	0.02	0.02	0.02	0.02	5.7e-03	2.6e-03	1.3e-03	4.5e-03
4	NAcc	gene expression	Spata31g1	0.04	0.03	5.4e-05	0	0.02	0.02	0.02	5.7e-02	1.2e-04	3.9e-04	1.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.3	0.6	2.0	1.4	-0.6	0.0	0.1
Area under the delay curve	0.1	0.2	0.5	-0.7	0.3	0.2	-0.2
BMI with tail	0.6	2.2	5.2	2.3	-1.5	0.8	-0.8
BMI without tail	0.7	3.5	7.2	2.7	-2.0	1.3	-1.2
Body weight	2.7	11.7	16.3	4.0	-3.6	3.0	-3.0
Weight adjusted by age	0.1	0.4	0.7	0.5	-0.5	0.7	-0.9
Bone surface	0.4	0.8	1.7	1.3	-0.9	0.6	-0.6
Bone volume	0.2	0.4	1.2	1.1	-0.5	0.2	-0.1
Breakpoint value in progressive ratio session	1.2	2.1	4.0	-0.2	-0.8	2.0	-2.0
Number of licking bursts	1.0	2.9	6.0	2.5	-2.0	1.0	-0.9
Context. condit. distance diff. score	0.2	0.2	0.2	-0.5	0.4	-0.5	0.5
Locomotion velocity, session 1	5.6	6.3	9.5	1.1	-2.3	3.0	-3.1
Locomotion distance, session 1	1.7	2.2	3.2	0.9	-1.3	1.7	-1.8
Locomotion velocity, session 2	0.6	0.7	2.2	1.5	-0.8	0.3	-0.3
Locomotion distance, session 2	2.8	4.0	4.3	2.1	-2.0	1.9	-2.0
Locomotion velocity, session 3	1.1	1.3	2.0	0.4	-1.1	1.4	-1.4
Locomotion distance, session 3	2.8	3.2	3.2	1.8	-1.8	1.8	-1.8
Stereotopy head waving bouts, day 3	0.6	0.7	1.3	-0.1	-0.7	1.1	-1.1
Stereotopy head waving duration, day 3	0.1	0.1	0.2	-0.5	-0.1	0.4	-0.4
Locomotion velocity, session 7	0.0	0.0	0.1	-0.3	0.2	-0.2	0.1
Locomotion distance, session 7	0.4	0.5	0.7	0.7	-0.7	0.8	-0.8
Stereotopy head waving bouts, day 7	1.5	1.8	2.3	1.3	-1.5	1.3	-1.2
Stereotopy head waving duration, day 7	0.7	0.9	1.3	0.9	-1.1	0.9	-0.9
Locomotion velocity, session 8	0.7	0.9	1.3	0.3	-1.0	1.1	-1.1
Locomotion distance, session 8	0.7	1.1	1.5	0.7	-1.0	1.2	-1.2
Degree of sensitization distance	0.9	0.9	1.3	-1.1	1.0	-0.8	0.9
Degree of sensitization stereotypy	0.9	1.0	1.5	1.2	-1.2	0.8	-0.7
Conditioned locomotion	0.4	0.5	0.8	0.0	-0.5	0.9	-0.9
Cocaine response after cond. corrected	0.4	0.6	1.3	-1.1	0.0	0.7	-0.8
Cocaine response after cond. not corrected	0.5	0.7	1.1	-0.9	-0.2	1.0	-1.0
Cocaine response before conditioning	0.4	0.5	1.2	1.1	-0.6	0.4	-0.3
Saline control response	2.1	2.9	3.5	1.3	-1.9	1.8	-1.8
Bone: connectivity density	0.2	0.3	0.6	0.8	-0.1	-0.4	0.5
Bone: cortical apparent density	0.6	0.9	1.7	-0.1	0.7	-1.2	1.3
Bone: cortical area	0.6	1.1	3.6	1.9	-0.8	-0.1	0.0
Bone: cortical porosity	0.3	0.3	0.4	-0.6	0.5	-0.5	0.5
Bone: cortical porosity	0.0	0.0	0.0	-0.1	-0.1	0.1	-0.1
Bone: cortical thickness	0.4	0.7	1.1	0.9	0.2	-1.0	1.0
Bone: cortical thickness	0.9	1.0	1.5	-0.5	1.1	-1.1	1.2
Bone: cortical tissue density	0.5	0.9	1.5	-0.2	0.7	-1.2	1.2
Condit. Reinf. active minus inactive responses	0.1	0.2	0.4	0.7	-0.4	0.2	-0.1
Condit. Reinf. active-inactive response ratio	0.7	0.7	0.8	-0.9	0.8	-0.8	0.8
Condit. Reinf. active responses	1.1	1.4	3.2	1.8	-1.2	0.6	-0.6
Condit. Reinf. inactive responses	1.1	1.4	4.2	2.0	-1.1	0.4	-0.5
Incentive salience index mean	2.7	3.5	5.7	2.4	-2.1	1.4	-1.4
Condit. Reinf. lever presses	8.3	12.4	16.5	4.1	-3.9	3.0	-3.0
Condit. Reinf. active minus inactive responses	0.2	0.3	0.9	1.0	-0.6	0.2	-0.1
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	0.2	0.1	-0.4	0.3
Condit. Reinf. active responses	1.2	1.7	3.8	1.9	-1.3	0.9	-0.8
Condit. Reinf. inactive responses	1.0	1.5	4.0	2.0	-1.2	0.6	-0.4
Condit. Reinf. lever presses	0.7	1.0	3.4	1.8	-0.7	-0.0	0.2
Condit. Reinf. lever reinforcers received	1.4	2.0	4.3	2.1	-1.4	0.9	-0.8
Conditioned reinforcement - actives	0.1	0.3	0.5	-0.1	-0.7	0.6	-0.4
Conditioned reinforcement - inactives	0.1	0.2	0.3	-0.5	-0.5	0.3	-0.3
Conditioned locomotion	0.4	0.5	1.0	0.2	-0.6	1.0	-0.9
Patch foraging indifference point 0 sec	1.3	3.7	5.8	0.8	-1.7	2.3	-2.4
Patch foraging indifference point AUC	3.3	7.9	13.3	3.6	-2.8	2.3	-2.3
Delay disc. indifference point, 0s delay	0.3	0.3	1.0	-1.0	0.3	0.1	-0.1
Delay disc. indifference point, 16s delay	0.3	0.4	0.7	-0.8	-0.1	0.7	-0.7
Delay disc. indifference point, 2s delay	0.1	0.1	0.2	0.0	0.0	-0.4	0.4
Delay disc. indifference point, 24s delay	0.1	0.1	0.2	-0.4	0.5	-0.3	0.3
Delay disc. indifference point, 4s delay	0.0	0.0	0.1	-0.3	0.3	0.0	0.0
Delay disc. indifference point, 8s delay	0.0	0.0	0.0	0.1	0.1	0.1	-0.1
Indifference point function ln k	0.8	2.4	4.9	-2.2	1.5	-1.1	1.2
Indifference point function log k	0.8	2.4	4.9	-2.2	1.5	-1.1	1.2
Patch foraging total patch changes 0 sec	1.5	4.3	6.1	1.2	-1.9	2.4	-2.5
Patch foraging total patch changes 12 sec	1.3	1.7	2.8	1.7	-1.3	1.0	-1.1
Patch foraging total patch changes 18 sec	0.5	1.2	1.4	1.2	-1.1	1.0	-1.1
Patch foraging total patch changes 24 sec	1.0	3.3	4.0	2.0	-1.9	1.6	-1.7
Patch foraging total patch changes 6 sec	3.6	6.1	6.6	2.3	-2.5	2.5	-2.6
Patch foraging time to switch 0 sec	1.1	4.4	6.0	-2.5	2.0	-1.9	2.0
Patch foraging water rate 0 sec	0.9	3.6	3.7	1.9	-1.9	1.8	-1.9
Patch foraging water rate 12 sec	0.1	0.2	0.3	0.3	-0.4	0.5	-0.6
Patch foraging water rate 18 sec	0.1	0.2	0.4	0.6	-0.2	-0.2	0.4
Patch foraging water rate 24 sec	0.7	1.0	1.5	-0.3	0.8	-1.2	1.2
Patch foraging water rate 6 sec	0.6	0.9	1.6	1.1	-1.3	0.8	-0.6
Seeking ratio, delayed vs. immediate footshock	1.5	2.2	4.1	2.0	-1.7	1.0	-0.9
Distance traveled before self-admin	2.6	5.6	7.2	2.4	-2.7	2.2	-2.1
Distance traveled after self-admin	0.4	0.6	1.4	1.1	-1.2	0.2	-0.1
Extensor digitorum longus weight	3.4	13.7	22.7	4.8	-4.0	2.8	-2.8
Bone: elastic displacement	5.8	7.4	9.5	-2.8	3.1	-2.5	2.4
Bone: elastic work	6.1	8.0	10.1	-2.0	2.9	-3.2	3.1
Bone: endosteal estimation	1.3	3.2	3.5	1.8	-1.9	1.7	-1.8
Bone: endosteal perimeter	1.5	3.7	4.1	1.8	-1.9	1.9	-2.0
Epididymis fat weight	0.1	0.4	1.2	1.1	-0.5	0.2	-0.2
Delta time in closed arm before/after self-admin	0.4	0.3	0.6	0.4	0.3	-0.8	0.7
Delta time in open arm before/after self-admin	0.2	0.2	0.3	-0.4	-0.2	0.6	-0.5
Diff in mean of infusions in LGA sessions	0.3	0.5	0.6	-0.4	0.7	-0.7	0.8
Delay discount exponential model param	0.1	0.1	0.3	0.6	-0.3	-0.2	0.2
Extinction: sum of active levers before priming	0.8	1.3	3.6	-1.9	1.1	-0.4	0.5
Active lever presses in extinction session 6	0.1	0.1	0.3	-0.5	0.4	-0.2	0.1
Bone: final force	0.8	1.4	3.1	1.8	-1.2	0.7	-0.7
Bone: final moment	0.5	0.9	2.3	1.5	-0.9	0.3	-0.3
Food consumed during 24 hour testing period	0.7	1.4	1.6	1.2	-1.3	1.1	-1.1
Glucose	1.8	2.9	5.1	2.3	-1.7	1.4	-1.4
Heart weight	0.4	0.6	1.6	1.3	-0.6	0.4	-0.5
Delay discount hyperbolic model param	0.1	0.1	0.2	0.4	-0.2	-0.3	0.3
Intermittent access intake day 1-15 change	0.0	0.2	0.4	0.6	-0.5	0.1	-0.0
Intermittent access intake escalation	0.0	0.1	0.3	0.5	-0.3	-0.1	0.2
Intermittent access intake escalation 2	0.2	0.3	0.4	0.6	-0.4	-0.5	0.7
Intermitt. access day 1 inactive lever presses	0.1	1.4	2.1	1.4	-1.2	1.0	-1.1
Intermitt. access day 15 inactive lever presses	0.0	0.2	0.3	0.1	-0.5	0.5	-0.4
Intermitt. access escalation Index	0.2	0.7	0.9	0.9	-0.7	0.9	-0.8
Intermittent access day 1 total infusions	0.2	0.6	1.9	-1.4	0.2	0.6	-0.4
Intermittent access day 15 total infusions	0.0	0.0	0.0	-0.2	-0.2	0.2	-0.0
Intermittent access terminal intake (last 3 days)	0.2	0.3	0.7	-0.0	-0.8	0.6	-0.4
Intermittent access total infusions	0.4	0.5	0.7	-0.0	-0.8	0.9	-0.7
Intermittent access day 1 locomotion	0.3	0.5	1.4	-1.2	0.6	0.3	-0.3
Intermittent access day 15 total locomotion	0.1	0.4	1.3	-1.1	0.6	0.0	-0.1
Intermittent access total locomotion	0.9	1.0	2.4	-1.5	1.0	-0.6	0.7
Intermittent access standard deviation	0.1	0.4	0.7	0.4	-0.8	0.7	-0.6
Left kidney weight	0.5	4.4	4.8	2.0	-2.2	2.0	-2.2
Right kidney weight	0.2	1.5	3.1	1.8	-1.0	0.8	-1.1
Cocaine induced anxiety	0.0	0.1	0.2	-0.4	-0.3	-0.1	0.2
Post-drug Anxiety	1.1	1.2	2.0	1.0	-1.4	1.0	-0.9
Baseline Anxiety	0.2	0.4	1.0	1.0	-0.6	0.3	-0.3
Tail length	1.0	5.2	8.6	2.9	-2.4	1.8	-1.8
Length with tail	1.9	8.6	9.0	2.9	-3.0	2.9	-2.9
Length without tail	0.3	1.8	2.7	0.4	-1.2	1.6	-1.6
Times rat made contact with spout	0.1	0.1	0.3	0.5	-0.4	-0.2	0.2
Lifetime Intake	0.9	1.2	1.9	-0.0	-1.2	1.4	-1.2
Liver weight, left	0.0	0.1	0.2	0.1	-0.1	0.3	-0.4
Liver weight, right	0.6	1.1	1.9	-1.4	0.9	-0.9	1.0
Locomotor activity	0.0	0.0	0.0	0.1	-0.1	0.1	-0.0
Locomotor testing distance	0.1	0.3	0.5	-0.2	-0.3	0.7	-0.7
Locomotor testing rearing	0.4	1.6	2.2	1.2	-1.5	1.2	-1.1
Locomotion in novel chamber	0.6	0.8	1.1	-0.8	0.9	-1.0	1.0
Locomotion in novel chamber post-restriction	0.2	0.5	1.1	1.0	-0.1	-0.7	0.7
Fecal boli incidents, locomotor time 1	0.6	1.6	2.2	-1.2	1.5	-1.2	1.0
Change in fecal boli incidents, locomotor task	1.4	1.4	1.6	1.2	-1.1	1.2	-1.2
Time >=10cm from walls, locomotor time 1	0.6	0.8	1.2	0.4	-0.8	1.1	-1.1
Bouts of movement, locomotor time 1	1.3	1.7	2.7	-1.6	1.4	-1.0	1.1
Total resting periods, locomotor time 1	2.6	3.0	3.7	-1.9	1.8	-1.5	1.6
Rest time, locomotor task time 1	3.6	5.8	7.2	-1.8	2.4	-2.7	2.6
Distance moved, locomotor task time 1	2.0	5.6	6.5	1.9	-2.4	2.6	-2.5
Vertical activity count, locomotor time 1	0.8	5.8	7.5	1.6	-2.5	2.7	-2.6
Time >=10cm from walls, locomotor time 2	0.1	0.2	0.3	0.4	-0.5	0.5	-0.5
Bouts of movement, locomotor time 2	0.1	0.4	0.6	0.8	-0.8	0.6	-0.5
Total resting periods, locomotor time 2	0.0	0.1	0.2	0.4	-0.4	0.2	-0.2
Rest time, locomotor task time 2	0.9	1.5	1.8	-1.2	1.3	-1.2	1.2
Distance moved, locomotor task time 2	0.1	0.1	0.4	0.6	-0.4	0.0	0.0
Vertical activity count, locomotor time 2	0.5	1.1	1.5	1.0	-1.2	1.0	-1.0
Light reinforcement 1	1.9	8.7	11.9	1.8	-2.9	3.4	-3.3
Light reinforcement 2	2.8	6.3	9.5	0.9	-2.3	3.1	-3.1
Bone: marrow area	1.2	2.9	3.3	1.8	-1.8	1.5	-1.7
Bone: maximum diameter	0.9	1.8	4.5	2.1	-1.4	0.7	-0.7
Bone: maximum force	1.4	2.8	6.3	2.5	-1.8	0.9	-0.9
Bone: maximum moment	1.0	1.9	4.9	2.2	-1.4	0.6	-0.6
Mean time between licks in bursts	0.1	0.4	0.6	-0.7	0.8	-0.6	0.5
Mean num. licks in bursts	0.8	2.0	3.2	-1.8	1.6	-1.1	1.1
Cd content in liver	0.9	1.0	1.4	1.2	-0.9	0.9	-0.9
Co content in liver	0.2	0.2	0.3	-0.5	0.1	0.5	-0.5
Cu content in liver	1.6	1.9	2.5	-1.6	1.6	-1.2	1.2
Fe content in liver	0.2	0.3	0.5	-0.7	-0.1	0.5	-0.5
K content in liver	0.1	0.1	0.3	-0.3	-0.0	0.4	-0.5
Mg content in liver	0.4	0.4	1.0	-1.0	0.7	-0.3	0.2
Mn content in liver	0.2	0.3	0.9	1.0	-0.3	-0.2	0.1
Na content in liver	1.0	1.1	1.6	-1.3	1.2	-0.9	0.8
Rb content in liver	2.3	2.7	6.1	-2.5	1.6	-1.0	1.0
Se content in liver	0.8	1.0	2.4	1.5	-1.1	0.4	-0.3
Sr content in liver	0.2	0.2	0.4	0.6	0.0	0.3	-0.5
Zn content in liver	0.1	0.1	0.1	0.2	0.3	-0.3	0.2
Bone: minimum diameter	0.1	0.3	0.4	-0.3	0.6	-0.7	0.6
Time in familiar zone, hab. session 1	3.4	3.8	5.6	-0.9	1.8	-2.3	2.4
Time in novel zone, hab. session 1	0.9	1.0	1.8	-0.9	-0.3	1.2	-1.3
Total zone transitions, hab. session 1	0.0	0.0	0.0	0.1	0.2	-0.1	0.0
Total locomotion distance, hab. session 1	0.4	0.5	0.9	0.5	0.5	-0.9	0.9
Locomotion velocity, hab. session 1	0.4	0.5	1.8	1.3	-0.3	-0.2	0.2
Time in familiar zone, hab. session 2	2.4	2.7	3.4	-1.1	1.7	-1.8	1.8
Time in novel zone, hab. session 2	0.5	0.6	0.9	-0.8	-0.3	0.9	-0.9
Total zone transitions, hab. session 2	1.2	1.6	1.9	1.0	-1.3	1.3	-1.4
Total locomotion distance, hab. session 2	0.5	0.6	1.1	1.1	-0.8	0.5	-0.6
Locomotion velocity, hab. session 2	0.6	0.7	1.5	1.2	-0.9	0.5	-0.6
Novel to familiar place preference ratio	0.8	1.1	3.3	-1.8	0.9	0.1	-0.1
Novelty place preference	1.3	1.6	4.8	-2.2	1.3	-0.3	0.2
Time in novel zone, NPP test	1.6	2.0	5.8	-2.4	1.4	-0.3	0.2
Total zone transitions, NPP test	1.5	2.2	2.7	1.3	-1.4	1.6	-1.6
Total locomotion distance, NPP test	2.3	3.3	3.3	1.8	-1.8	1.8	-1.8
Locomotion velocity, NPP test	2.4	3.4	4.2	2.0	-1.9	1.7	-1.7
Intraocular pressure	2.3	3.8	4.3	2.1	-2.1	1.9	-1.8
Delta distance traveled before/after self-admin	0.3	0.3	0.5	-0.5	0.2	-0.6	0.7
Delta ambulatory time before/after self-admin	0.6	1.0	1.2	-1.1	0.8	-1.1	1.1
Parametrial fat weight	0.1	0.3	0.6	0.1	-0.1	0.7	-0.8
Pavlov. Cond. lever latency	5.5	6.9	9.6	-3.1	2.9	-2.2	2.1
Pavlov. Cond. magazine entry latency	0.2	0.3	0.7	0.8	-0.5	0.4	-0.4
Pavlov. Cond. change in total contacts	2.4	2.6	3.2	1.8	-1.8	1.4	-1.4
Pavlov. Cond. index score	2.0	2.5	4.4	2.1	-1.8	1.2	-1.2
Pavlov. Cond. latency score	1.9	2.4	4.0	2.0	-1.7	1.2	-1.2
Pavlov. Cond. lever contacts	4.6	5.6	8.2	2.9	-2.7	1.9	-1.8
Pavlov. Cond. magazine entry number	0.2	0.3	0.9	-1.0	0.5	-0.2	0.2
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	0.4	-0.3	0.2	-0.1
Pavlov. Cond. lever-magazine prob. diff.	1.6	2.0	4.1	2.0	-1.6	0.9	-0.9
Pavlov. Cond. response bias	2.7	3.3	5.6	2.4	-1.9	1.4	-1.4
Pavlov. Cond. lever latency	0.7	0.9	3.2	-1.8	0.7	0.0	-0.1
Pavlov. Cond. magazine entry latency	0.4	0.5	0.7	-0.6	0.7	-0.8	0.9
Pavlov. Cond. change in total contacts	0.4	1.0	1.6	0.8	0.5	-1.2	1.3
Pavlov. Cond. index score	0.4	0.6	1.0	0.4	0.5	-0.9	1.0
Pavlov. Cond. latency score	0.4	0.6	1.1	0.5	0.4	-1.0	1.1
Pavlov. Cond. lever contacts	0.4	0.7	2.4	1.5	-0.5	-0.1	0.2
Pavlov. Cond. magazine entry number	0.7	0.9	1.6	-0.1	-0.7	1.2	-1.3
Pavlov. Cond. intertrial magazine entries	0.2	0.4	0.4	0.6	-0.6	0.6	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.7	1.2	0.4	0.6	-1.0	1.1
Pavlov. Cond. response bias	0.3	0.4	0.9	0.9	0.1	-0.6	0.7
Time in closed arm before self-admin	0.2	0.3	0.5	-0.7	0.6	-0.4	0.5
Time in closed arm after self-admin	1.0	1.1	1.7	-0.7	0.9	-1.3	1.3
Time in open arm before self-admin	1.6	1.9	2.2	1.4	-1.3	1.4	-1.5
Time in open arm after self-admin	1.9	2.1	2.6	1.2	-1.4	1.6	-1.6
Bone: periosteal estimation	0.9	2.2	4.3	2.1	-1.5	1.0	-1.1
Bone: periosteal perimeter	0.6	1.2	1.4	1.2	-1.1	1.0	-1.1
Bone: post-yield work	2.2	3.9	4.2	2.1	-2.0	1.9	-1.9
Progressive ratio test 1 active lever presses	0.6	1.1	1.8	-0.7	-1.0	1.4	-1.0
Progressive ratio test 1 breakpoint	0.6	1.1	1.8	-0.6	-1.0	1.3	-1.0
Progressive ratio test 1 inactive lever presses	1.4	3.7	4.8	1.1	-2.1	2.2	-2.1
Progressive ratio test 2 active lever presses	0.8	1.1	1.8	-0.8	-1.0	1.3	-1.1
Progressive ratio test 2 breakpoint	0.9	1.2	1.8	-0.8	-0.9	1.4	-1.1
Progressive ratio test 2 inactive lever presses	0.2	0.5	0.8	0.2	-0.8	0.9	-0.7
Incentive Sensitization - Responses	0.2	0.6	1.0	-0.5	-1.0	0.9	-0.7
Incentive Sensitization - Breakpoint	0.2	0.5	0.8	-0.6	-0.9	0.8	-0.6
Sum of active levers in priming session hrs 5-6	0.8	0.7	2.4	-1.5	0.7	0.2	-0.3
Progressive ratio	0.0	0.0	0.1	0.2	-0.1	0.2	-0.3
Food seeking constrained by brief footshock	9.8	12.3	15.6	3.5	-3.9	3.3	-3.2
Seeking ratio, punishment vs. effort	1.2	2.6	3.8	1.7	-1.9	1.4	-1.3
Retroperitoneal fat weight	0.5	2.3	2.8	-1.4	1.7	-1.5	1.5
Reaction time number correct	0.1	0.5	0.7	0.6	-0.6	0.8	-0.8
Reaction time mean minus median	0.4	2.4	3.9	0.3	1.3	-2.0	1.9
Reaction time mean minus median AUC	0.1	1.0	1.5	0.9	0.5	-1.2	1.2
Reaction time num false alarms	0.1	0.2	0.4	-0.1	0.3	-0.6	0.6
Reaction time num false alarms AUC	0.1	0.2	0.4	0.6	-0.5	0.3	-0.2
Reaction time trials correct on left	0.1	0.5	0.7	0.6	-0.6	0.8	-0.8
Reaction time trials on left	0.1	0.4	0.6	0.5	-0.5	0.7	-0.8
Reaction time mean	2.5	5.4	6.8	-1.6	2.4	-2.6	2.6
Reaction time mean AUC	2.5	6.1	7.7	-1.7	2.5	-2.8	2.8
Median of all reaction times	3.4	5.4	5.9	-2.2	2.4	-2.3	2.3
Reaction time omissions	1.4	2.2	3.2	-1.8	1.7	-1.2	1.1
Reaction time false alarm rate	0.2	0.3	0.5	-0.4	0.4	-0.6	0.7
Reaction time premature initiation rate	2.8	4.4	5.0	-2.2	2.2	-1.9	2.0
Reaction time premature initiations	0.8	2.3	3.0	-1.7	1.7	-1.3	1.3
Std. dev. reaction times	1.1	3.7	5.5	-0.6	1.9	-2.3	2.3
Reaction time trials completed	0.1	0.4	0.6	0.5	-0.5	0.7	-0.8
Reaction time trials AUC	0.1	0.4	0.5	0.5	-0.4	0.7	-0.7
Run reversals in cocaine runway, females	0.4	0.4	0.7	0.4	0.7	-0.8	0.6
Run reversals in cocaine runway, males	0.1	0.1	0.1	-0.3	0.2	-0.2	0.2
Latency to leave start box in cocaine runway	0.2	0.3	0.8	0.9	-0.5	0.2	-0.3
Latency to leave start box in cocaine runway, F	0.0	0.1	0.2	-0.1	0.0	0.3	-0.4
Latency to leave start box in cocaine runway, M	1.7	1.6	2.7	1.6	-1.5	0.9	-0.9
Std. dev. time between licks in bursts	0.2	0.4	0.5	-0.7	0.7	-0.5	0.6
Total sessions with >9 infusions	1.6	2.0	3.2	0.1	-1.6	1.8	-1.5
Short access day 1 total inactive lever presses	1.6	3.2	4.1	1.0	-2.0	2.0	-1.9
Short access day 10 total inactive lever presses	0.1	0.4	1.0	1.0	-0.6	0.3	-0.3
Short access day 1 total infusions	1.4	2.8	4.4	0.3	-1.9	2.1	-1.8
Short access day 10 total infusions	0.9	1.4	2.5	0.0	-1.1	1.6	-1.4
Short access total infusions	1.4	2.0	3.5	-0.3	-1.4	1.9	-1.6
Short access day 1 locomotion	0.3	0.5	1.0	-1.0	0.3	0.7	-0.5
Short access day 10 total locomotion	0.3	1.4	1.7	-1.3	1.3	-1.0	1.1
Short access total locomotion	0.1	0.2	0.4	-0.5	0.0	0.6	-0.5
One hour access (0.3 mA shock)	0.9	1.0	1.4	0.5	-1.0	1.2	-1.2
Compulsive drug intake	0.2	0.2	0.4	0.4	0.4	-0.6	0.5
One hour access (shock baseline)	0.7	1.9	3.0	0.3	-1.3	1.7	-1.6
Social response proportion	2.4	3.1	3.8	-1.7	2.0	-1.7	1.6
Social responses	0.4	0.5	1.0	1.0	-0.7	0.5	-0.5
Social time	0.0	0.0	0.0	-0.2	0.0	0.0	-0.1
Soleus weight	1.1	3.3	5.4	0.6	-1.6	2.2	-2.3
Bone: stiffness	2.0	3.7	7.6	2.8	-2.1	1.2	-1.2
Tibialis anterior weight	6.9	23.9	34.6	5.9	-5.3	4.1	-4.0
Time to tail flick, vehicle, before self-admin	0.9	1.1	2.1	-0.7	1.4	-1.1	0.9
Time to tail flick, vehicle, after self-admin	0.0	0.0	0.1	-0.1	0.0	-0.2	0.3
Time to tail flick, test, before self-admin	0.3	0.3	0.7	0.8	-0.7	0.3	-0.3
Time to tail flick, test, after self-admin	0.6	0.7	2.1	1.5	0.0	-0.5	0.5
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.6	0.2	-0.8	0.4	-0.3
Delta time to tail flick, test, before/after SA	0.5	0.6	0.8	-0.2	0.9	-0.9	0.9
Tibia length	0.6	1.6	2.6	0.6	-1.2	1.5	-1.6
Ambulatory time before self-admin	1.6	4.8	6.0	2.1	-2.4	2.1	-2.1
Ambulatory time after self-admin	0.4	0.6	1.2	0.7	-1.1	0.6	-0.6
Bone: tissue strength	0.0	0.0	0.1	0.4	-0.2	0.1	-0.1
Total heroin consumption	0.5	0.6	0.9	-0.9	-0.1	0.9	-0.8
Bone: trabecular number	0.2	0.4	1.4	1.2	-0.4	-0.1	0.2
Bone: trabecular spacing	0.1	0.1	0.2	-0.1	0.3	-0.4	0.4
Bone: trabecular thickness	0.4	0.5	0.7	-0.6	0.8	-0.8	0.8
Bone: trabecular tissue density	2.1	3.7	5.9	2.4	-2.1	1.5	-1.4
Water consumed over 24 hours	0.3	0.6	1.0	1.0	-1.0	0.4	-0.4
Number of responses in last shaping day	2.5	3.3	6.0	0.0	-1.4	2.4	-2.3