Hub : Genes

Spata31f3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS XM_006238096.5 0.02 0.02 1.1e-03 0.01 0 0.01 0.01 1.9e-03 4.7e-02 8.4e-03 8.2e-03
2 NAcc gene expression Spata31f3 0.03 0.02 1.6e-04 0.02 0.01 0.01 0.01 4.2e-04 6.6e-03 3.8e-03 9.0e-03
3 NAcc alternative TSS XM_006238096.5 0.02 0.01 6.7e-03 0.01 0 0 0 1.8e-02 1.7e-01 1.5e-01 9.9e-02
4 PL alternative TSS NM_001024343.2 0.03 0.02 2.0e-03 0.02 0.02 0.02 0.02 4.3e-03 6.4e-03 3.4e-03 3.4e-03
5 PL alternative TSS XM_006238096.5 0.03 0.02 1.7e-03 0.02 0.01 0.01 0.01 4.8e-03 4.2e-02 8.8e-03 7.3e-03
6 PL alternative TSS XM_039110562.2 0.03 0.02 4.7e-04 0.02 0.01 0.02 0.02 2.2e-03 1.2e-02 3.7e-03 2.9e-03
7 PL gene expression Spata31f3 0.06 0.06 4.5e-05 0.04 0.03 0.03 0.04 9.8e-06 6.9e-04 1.8e-04 3.8e-05
8 PL alternative TSS XM_006238096.5 0.02 0.02 3.3e-03 0.02 0.01 0.02 0.02 6.8e-03 1.3e-02 5.6e-03 6.7e-03
9 IC alternative TSS XM_006238096.5 0.11 0.07 7.9e-04 0.05 0.04 0.03 0.04 4.7e-03 6.3e-03 1.4e-02 1.2e-02
10 IC alternative TSS XM_006238096.5 0.1 0.07 2.7e-03 0.04 0.05 0.04 0.04 1.3e-02 3.7e-03 8.5e-03 1.1e-02
11 IC alternative TSS NM_001024343.2 0.1 0.07 2.8e-03 0.04 0.05 0.04 0.04 1.3e-02 3.7e-03 9.3e-03 1.1e-02
12 IC alternative TSS XM_039110562.2 0.1 0.07 1.3e-03 0.04 0.04 0.03 0.03 1.3e-02 1.1e-02 2.8e-02 2.5e-02
13 BLA gene expression Spata31f3 0.07 0.05 4.1e-03 0.03 0.02 0.03 0.02 8.2e-03 2.2e-02 1.4e-02 2.2e-02
14 Brain gene expression Spata31f3 0.04 0.03 6.6e-03 0.03 0.02 0.03 0.03 1.0e-03 4.1e-03 5.0e-04 2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density1.12.13.21.4-1.41.4-1.51.3-1.3-1.31.51.8-1.61.61.7-1.11.0
Area under the delay curve0.40.61.0-0.70.7-0.70.8-0.60.60.6-0.7-1.01.0-1.0-1.00.8-0.4
BMI with tail1.55.26.32.3-2.32.3-2.42.3-2.3-2.32.42.5-2.42.42.5-2.10.3
BMI without tail1.37.18.12.8-2.82.8-2.82.7-2.7-2.72.82.8-2.82.82.8-2.6-0.0
Body weight3.415.018.74.3-4.34.3-4.04.1-4.1-4.14.03.6-3.73.73.6-3.8-1.4
Weight adjusted by age0.10.21.50.5-0.50.5-0.40.5-0.5-0.50.30.1-0.20.20.1-0.3-1.2
Bone surface0.81.51.91.4-1.41.4-1.31.2-1.2-1.21.31.3-1.21.21.2-1.0-0.1
Bone volume0.61.21.71.1-1.11.1-1.21.0-1.0-1.01.21.3-1.21.21.2-0.80.4
Breakpoint value in progressive ratio session0.61.25.1-0.20.2-0.20.60.1-0.1-0.1-0.6-2.01.3-1.3-1.60.2-2.2
Number of licking bursts2.16.47.92.4-2.42.4-2.72.5-2.5-2.52.72.6-2.82.82.8-2.80.1
Context. condit. distance diff. score0.10.10.2-0.40.4-0.40.4-0.40.40.4-0.4-0.30.3-0.3-0.30.40.4
Locomotion velocity, session 11.41.511.71.1-1.11.1-0.61.1-1.1-1.10.7-0.5-0.00.0-0.3-1.1-3.4
Locomotion distance, session 10.50.73.80.8-0.80.8-0.60.9-0.9-0.90.7-0.0-0.30.30.1-0.7-1.9
Locomotion velocity, session 22.12.53.71.6-1.61.6-1.71.5-1.5-1.51.71.9-1.71.71.8-1.40.4
Locomotion distance, session 22.43.44.32.1-2.12.1-1.92.0-2.0-2.02.01.5-1.71.71.5-1.8-1.5
Locomotion velocity, session 30.20.32.10.4-0.40.4-0.20.5-0.5-0.50.2-0.40.0-0.0-0.2-0.6-1.4
Locomotion distance, session 32.32.63.41.8-1.81.8-1.71.8-1.8-1.81.71.2-1.41.41.3-1.7-1.2
Stereotopy head waving bouts, day 30.20.21.6-0.10.1-0.10.3-0.10.10.1-0.3-0.80.4-0.4-0.60.0-1.3
Stereotopy head waving duration, day 30.30.30.8-0.50.5-0.50.6-0.50.50.5-0.7-0.90.5-0.5-0.60.4-0.5
Locomotion velocity, session 70.10.10.1-0.30.3-0.30.3-0.30.30.3-0.3-0.30.3-0.3-0.30.30.0
Locomotion distance, session 70.30.30.50.7-0.70.7-0.60.6-0.6-0.60.60.4-0.40.40.4-0.6-0.6
Stereotopy head waving bouts, day 71.11.31.81.2-1.21.2-1.21.3-1.3-1.31.10.8-1.11.11.0-1.3-0.6
Stereotopy head waving duration, day 70.50.71.00.8-0.80.8-0.80.9-0.9-0.90.80.6-0.90.90.8-1.0-0.3
Locomotion velocity, session 80.20.22.00.4-0.40.4-0.10.3-0.3-0.30.1-0.20.1-0.1-0.2-0.4-1.4
Locomotion distance, session 80.30.41.60.7-0.70.7-0.50.7-0.7-0.70.60.2-0.30.30.2-0.6-1.2
Degree of sensitization distance1.01.11.4-1.11.1-1.11.1-1.21.21.2-1.1-1.01.0-1.0-1.01.10.5
Degree of sensitization stereotypy1.31.41.61.2-1.21.2-1.31.3-1.3-1.31.21.1-1.31.31.2-1.3-0.0
Conditioned locomotion0.10.21.60.0-0.00.00.10.2-0.2-0.2-0.0-0.50.2-0.2-0.3-0.2-1.2
Cocaine response after cond. corrected1.32.03.6-1.21.2-1.21.4-1.11.11.1-1.4-1.91.6-1.6-1.80.9-1.6
Cocaine response after cond. not corrected1.11.63.7-1.01.0-1.01.2-0.90.90.9-1.2-1.81.4-1.5-1.60.8-1.9
Cocaine response before conditioning0.81.01.21.0-1.01.0-1.11.0-1.0-1.01.11.0-1.11.11.1-0.90.1
Saline control response1.01.42.01.3-1.31.3-1.11.3-1.3-1.31.20.6-1.01.00.8-1.4-1.4
Bone: connectivity density0.50.81.60.8-0.80.8-0.90.7-0.7-0.70.91.3-1.01.01.1-0.51.1
Bone: cortical apparent density0.10.21.9-0.30.3-0.3-0.0-0.20.20.20.00.5-0.30.30.50.11.4
Bone: cortical area2.74.46.72.0-2.02.0-2.22.0-2.0-2.02.22.6-2.42.42.5-1.71.1
Bone: cortical porosity0.30.30.4-0.50.5-0.50.6-0.60.60.6-0.6-0.40.5-0.5-0.50.50.5
Bone: cortical porosity0.00.00.0-0.00.0-0.00.1-0.10.10.1-0.1-0.10.1-0.1-0.1-0.00.0
Bone: cortical thickness1.01.73.41.0-1.01.0-1.31.0-1.0-1.01.21.8-1.61.61.7-0.81.8
Bone: cortical thickness0.20.31.8-0.50.5-0.50.3-0.50.50.5-0.3-0.00.2-0.2-0.00.71.3
Bone: cortical tissue density0.10.21.6-0.30.3-0.30.1-0.20.20.2-0.10.4-0.20.20.30.11.3
Condit. Reinf. active minus inactive responses0.40.50.70.6-0.60.6-0.80.8-0.8-0.80.80.7-0.80.80.8-0.7-0.0
Condit. Reinf. active-inactive response ratio0.70.71.0-1.01.0-1.00.8-0.90.90.9-0.9-0.80.8-0.8-0.70.90.4
Condit. Reinf. active responses2.63.44.21.7-1.71.7-2.01.9-1.9-1.92.02.0-2.02.02.1-1.7-0.0
Condit. Reinf. inactive responses3.34.26.02.1-2.12.1-2.22.0-2.0-2.02.22.4-2.32.32.3-1.80.4
Incentive salience index mean4.25.46.22.3-2.32.3-2.52.5-2.5-2.52.52.2-2.42.42.4-2.3-0.7
Condit. Reinf. lever presses10.015.017.24.1-4.14.1-4.14.1-4.1-4.14.13.5-3.83.83.7-4.0-1.8
Condit. Reinf. active minus inactive responses0.61.01.51.1-1.11.1-1.00.9-0.9-0.91.01.2-1.01.01.1-0.90.4
Condit. Reinf. active-inactive response ratio0.10.10.50.4-0.40.4-0.30.2-0.2-0.20.30.7-0.30.30.4-0.10.6
Condit. Reinf. active responses2.53.64.32.1-2.12.1-2.01.9-1.9-1.92.02.0-1.91.91.9-1.70.1
Condit. Reinf. inactive responses2.74.05.32.0-2.02.0-2.12.0-2.0-2.02.12.1-2.32.32.3-1.90.6
Condit. Reinf. lever presses2.73.95.91.9-1.91.9-2.11.7-1.7-1.72.02.4-2.32.32.4-1.61.4
Condit. Reinf. lever reinforcers received2.94.15.02.2-2.22.2-2.12.0-2.0-2.02.12.2-2.12.12.1-1.90.1
Conditioned reinforcement - actives0.00.10.60.1-0.10.10.2-0.20.20.20.0-0.2-0.10.10.0-0.70.4
Conditioned reinforcement - inactives0.10.30.8-0.50.5-0.50.7-0.70.70.7-0.6-0.90.4-0.4-0.5-0.0-0.1
Conditioned locomotion0.00.00.30.2-0.20.2-0.00.1-0.1-0.10.2-0.4-0.00.0-0.1-0.5-0.2
Patch foraging indifference point 0 sec0.30.97.80.9-0.90.9-0.40.7-0.7-0.70.4-0.50.0-0.0-0.3-0.7-2.8
Patch foraging indifference point AUC4.711.214.13.8-3.83.8-3.53.5-3.5-3.53.53.4-3.23.23.1-3.3-1.0
Delay disc. indifference point, 0s delay0.91.01.8-1.01.0-1.01.1-0.90.90.9-1.1-1.31.2-1.2-1.30.8-0.5
Delay disc. indifference point, 16s delay0.71.02.5-0.80.8-0.81.0-0.50.50.5-0.9-1.61.3-1.3-1.40.8-1.2
Delay disc. indifference point, 2s delay0.10.10.50.0-0.00.0-0.10.0-0.0-0.00.20.4-0.30.30.40.00.7
Delay disc. indifference point, 24s delay0.10.10.4-0.40.4-0.40.3-0.10.10.1-0.3-0.30.4-0.4-0.40.60.0
Delay disc. indifference point, 4s delay0.10.10.2-0.30.3-0.30.3-0.30.30.3-0.3-0.40.4-0.4-0.40.40.1
Delay disc. indifference point, 8s delay0.00.00.00.1-0.10.1-0.10.0-0.0-0.00.10.1-0.00.00.0-0.10.0
Indifference point function ln k1.34.05.1-2.32.3-2.32.1-2.02.02.0-2.1-2.22.0-2.0-1.91.90.3
Indifference point function log k1.34.05.1-2.32.3-2.32.1-2.02.02.0-2.1-2.22.0-2.0-1.91.90.3
Patch foraging total patch changes 0 sec0.41.37.01.2-1.21.2-0.81.1-1.1-1.10.8-0.1-0.40.40.2-1.1-2.6
Patch foraging total patch changes 12 sec1.92.53.01.7-1.71.7-1.71.7-1.7-1.71.71.6-1.51.51.5-1.7-0.6
Patch foraging total patch changes 18 sec0.51.21.81.3-1.31.3-1.11.1-1.1-1.11.11.0-0.80.80.7-1.0-1.0
Patch foraging total patch changes 24 sec0.93.14.52.1-2.12.1-1.81.8-1.8-1.81.81.6-1.51.51.4-1.7-1.3
Patch foraging total patch changes 6 sec2.44.05.32.3-2.32.3-2.02.2-2.2-2.22.01.3-1.51.51.4-2.1-2.3
Patch foraging time to switch 0 sec1.14.16.0-2.42.4-2.42.1-2.12.12.1-2.1-1.81.8-1.8-1.71.81.5
Patch foraging water rate 0 sec0.72.73.71.9-1.91.9-1.61.7-1.7-1.71.61.1-1.31.31.2-1.6-1.8
Patch foraging water rate 12 sec0.00.00.30.3-0.30.3-0.10.2-0.2-0.20.1-0.1-0.00.0-0.00.1-0.6
Patch foraging water rate 18 sec0.20.51.20.5-0.50.5-0.60.5-0.5-0.50.60.8-0.80.80.9-0.41.1
Patch foraging water rate 24 sec0.10.21.7-0.30.3-0.30.2-0.40.40.4-0.20.3-0.10.10.20.51.3
Patch foraging water rate 6 sec0.81.11.61.0-1.01.0-1.01.0-1.0-1.01.10.9-1.31.31.2-1.2-0.0
Seeking ratio, delayed vs. immediate footshock2.94.15.31.8-1.81.8-2.22.3-2.3-2.32.21.8-2.22.22.2-2.2-0.3
Distance traveled before self-admin2.96.39.62.4-2.42.4-2.63.1-3.1-3.12.71.6-2.42.42.3-2.5-1.3
Distance traveled after self-admin1.32.23.81.1-1.11.1-1.51.5-1.5-1.51.71.4-1.91.92.0-1.50.7
Extensor digitorum longus weight5.321.023.64.8-4.84.8-4.84.9-4.9-4.94.84.4-4.74.74.6-4.6-1.0
Bone: elastic displacement5.67.09.0-2.82.8-2.82.7-2.92.92.9-2.8-2.22.6-2.6-2.53.01.2
Bone: elastic work2.63.47.9-2.02.0-2.01.7-2.02.02.0-1.8-0.71.3-1.3-1.02.12.8
Bone: endosteal estimation1.22.93.61.9-1.91.9-1.71.9-1.9-1.91.71.4-1.51.51.4-1.7-1.3
Bone: endosteal perimeter1.12.83.61.9-1.91.9-1.71.9-1.9-1.91.81.2-1.51.51.3-1.6-1.4
Epididymis fat weight0.21.21.91.1-1.11.1-1.21.1-1.1-1.11.11.4-1.21.21.2-0.90.1
Delta time in closed arm before/after self-admin0.50.51.20.4-0.40.4-0.80.6-0.6-0.60.71.1-0.80.80.90.00.8
Delta time in open arm before/after self-admin0.30.30.9-0.40.4-0.40.7-0.50.50.5-0.6-0.90.6-0.6-0.7-0.1-0.5
Diff in mean of infusions in LGA sessions0.10.11.0-0.40.4-0.40.2-0.30.30.3-0.30.00.0-0.00.00.11.0
Delay discount exponential model param0.30.50.90.6-0.60.6-0.70.5-0.5-0.50.60.9-0.90.90.9-0.70.4
Extinction: sum of active levers before priming2.23.45.9-2.12.1-2.11.9-1.51.51.5-1.8-2.42.0-2.0-2.01.7-0.0
Active lever presses in extinction session 60.30.30.6-0.50.5-0.50.4-0.20.20.2-0.5-0.70.8-0.8-0.80.70.1
Bone: final force2.13.44.21.9-1.91.9-1.91.8-1.8-1.81.92.0-2.02.02.0-1.70.3
Bone: final moment1.72.73.81.7-1.71.7-1.71.6-1.6-1.61.72.0-1.81.81.8-1.50.5
Food consumed during 24 hour testing period0.61.31.71.2-1.21.2-1.21.2-1.2-1.21.21.0-1.11.11.0-1.3-0.9
Glucose2.64.15.22.3-2.32.3-2.22.1-2.1-2.12.12.1-2.02.01.9-2.0-0.7
Heart weight0.81.21.71.2-1.21.2-1.21.3-1.3-1.31.21.2-1.01.01.0-0.7-0.1
Delay discount hyperbolic model param0.20.30.60.4-0.40.4-0.50.4-0.4-0.40.50.7-0.70.70.8-0.50.4
Intermittent access intake day 1-15 change0.20.91.50.7-0.70.7-1.01.0-1.0-1.01.01.1-1.21.21.2-0.90.1
Intermittent access intake escalation0.10.81.50.6-0.60.6-0.90.9-0.9-0.90.91.0-1.21.21.2-0.70.4
Intermittent access intake escalation 20.81.32.70.6-0.60.6-1.10.9-0.9-0.91.11.4-1.61.61.7-1.21.1
Intermitt. access day 1 inactive lever presses0.11.92.71.4-1.41.4-1.51.6-1.6-1.61.51.1-1.31.31.2-1.2-0.9
Intermitt. access day 15 inactive lever presses0.00.10.30.1-0.10.1-0.20.5-0.5-0.50.3-0.1-0.40.40.4-0.4-0.3
Intermitt. access escalation Index0.20.71.20.9-0.90.9-0.91.1-1.1-1.10.80.5-0.70.70.7-0.8-0.2
Intermittent access day 1 total infusions0.82.44.7-1.31.3-1.31.7-1.51.51.5-1.6-2.21.9-1.9-2.01.0-0.3
Intermittent access day 15 total infusions0.00.00.3-0.10.1-0.10.1-0.10.10.10.0-0.1-0.10.10.1-0.20.5
Intermittent access terminal intake (last 3 days)0.10.10.90.0-0.00.0-0.00.1-0.1-0.10.2-0.2-0.30.30.3-0.90.2
Intermittent access total infusions0.00.10.50.0-0.00.00.2-0.20.20.2-0.0-0.40.0-0.0-0.1-0.7-0.1
Intermittent access day 1 locomotion1.12.03.3-1.11.1-1.11.5-1.41.41.4-1.5-1.81.8-1.8-1.81.1-0.3
Intermittent access day 15 total locomotion0.41.72.4-1.01.0-1.01.4-1.41.41.4-1.4-1.51.5-1.5-1.51.2-0.2
Intermittent access total locomotion1.92.33.2-1.41.4-1.41.7-1.81.81.8-1.6-1.51.5-1.5-1.41.30.7
Intermittent access standard deviation0.10.40.80.4-0.40.4-0.50.7-0.7-0.70.70.3-0.70.70.6-0.9-0.4
Left kidney weight0.43.24.62.1-2.12.1-1.82.0-2.0-2.01.71.2-1.41.41.2-1.6-2.1
Right kidney weight0.32.03.01.7-1.71.7-1.51.5-1.5-1.51.31.5-1.21.21.1-1.0-0.8
Cocaine induced anxiety0.00.10.2-0.40.4-0.40.4-0.50.50.5-0.3-0.30.1-0.1-0.1-0.2-0.3
Post-drug Anxiety0.70.81.81.0-1.01.0-0.80.7-0.7-0.70.90.6-0.80.80.8-1.3-0.9
Baseline Anxiety0.50.81.10.9-0.90.9-1.11.0-1.0-1.01.01.0-0.90.90.9-0.80.2
Tail length1.58.310.03.2-3.23.2-3.13.0-3.0-3.03.02.9-2.82.82.8-2.8-0.7
Length with tail1.77.710.33.2-3.23.2-2.83.1-3.1-3.12.82.1-2.32.32.1-2.7-2.1
Length without tail0.10.42.60.5-0.50.5-0.30.8-0.8-0.80.4-0.40.0-0.0-0.2-0.5-1.6
Times rat made contact with spout0.40.40.70.5-0.50.5-0.70.6-0.6-0.60.70.7-0.80.80.9-0.80.5
Lifetime Intake0.10.10.70.1-0.10.10.2-0.10.10.1-0.0-0.70.1-0.1-0.3-0.8-0.5
Liver weight, left0.00.00.40.0-0.00.00.00.0-0.0-0.0-0.1-0.20.2-0.2-0.30.2-0.6
Liver weight, right0.71.31.7-1.31.3-1.31.3-1.31.31.3-1.2-1.01.0-1.0-0.90.90.8
Locomotor activity0.00.00.10.0-0.00.0-0.10.1-0.1-0.10.1-0.0-0.10.10.1-0.00.3
Locomotor testing distance0.10.20.7-0.30.3-0.30.4-0.30.30.3-0.4-0.90.5-0.5-0.60.3-0.7
Locomotor testing rearing0.31.11.91.1-1.11.1-1.01.0-1.0-1.01.10.7-1.21.21.1-1.4-0.5
Locomotion in novel chamber0.30.40.7-0.70.7-0.70.7-0.90.90.9-0.7-0.10.5-0.5-0.40.60.6
Locomotion in novel chamber post-restriction0.51.53.71.1-1.11.1-1.20.7-0.7-0.71.21.9-1.51.51.7-0.91.2
Fecal boli incidents, locomotor time 10.51.31.9-1.31.3-1.31.1-1.21.21.2-1.2-0.81.2-1.2-1.11.40.3
Change in fecal boli incidents, locomotor task0.80.81.11.1-1.11.1-0.91.0-1.0-1.00.90.4-0.70.70.6-0.9-0.9
Time >=10cm from walls, locomotor time 10.20.20.50.5-0.50.5-0.30.6-0.6-0.60.3-0.20.0-0.0-0.1-0.6-0.7
Bouts of movement, locomotor time 11.72.22.8-1.71.7-1.71.6-1.61.61.6-1.5-1.41.4-1.4-1.31.60.4
Total resting periods, locomotor time 12.52.93.7-1.91.9-1.91.8-1.91.91.9-1.8-1.41.5-1.5-1.41.90.9
Rest time, locomotor task time 11.42.25.1-1.71.7-1.71.3-1.71.71.7-1.3-0.20.9-0.9-0.61.92.3
Distance moved, locomotor task time 11.02.84.21.9-1.91.9-1.62.0-2.0-2.01.60.6-1.21.21.0-2.0-1.9
Vertical activity count, locomotor time 10.21.64.51.3-1.31.3-1.01.4-1.4-1.41.0-0.1-0.70.70.5-1.7-2.1
Time >=10cm from walls, locomotor time 20.00.10.50.3-0.30.3-0.30.4-0.4-0.40.30.1-0.20.20.1-0.4-0.7
Bouts of movement, locomotor time 20.20.50.90.7-0.70.7-0.60.6-0.6-0.60.70.7-0.80.80.8-0.9-0.2
Total resting periods, locomotor time 20.00.10.20.3-0.30.3-0.20.1-0.1-0.10.30.3-0.50.50.5-0.50.0
Rest time, locomotor task time 20.81.32.0-1.11.1-1.11.2-1.41.41.4-1.1-0.70.9-0.9-0.81.41.0
Distance moved, locomotor task time 20.50.61.00.5-0.50.5-0.80.8-0.8-0.80.80.9-1.01.01.0-0.80.3
Vertical activity count, locomotor time 20.30.71.10.8-0.80.8-0.81.0-1.0-1.00.80.5-0.80.80.7-1.0-0.8
Light reinforcement 10.62.79.01.7-1.71.7-1.31.9-1.9-1.91.40.0-0.90.90.6-2.0-3.0
Light reinforcement 20.51.28.21.0-1.01.0-0.51.1-1.1-1.10.6-0.70.0-0.0-0.3-1.2-2.9
Bone: marrow area1.23.03.71.9-1.91.9-1.81.9-1.9-1.91.81.5-1.61.61.5-1.7-1.0
Bone: maximum diameter2.54.96.12.2-2.22.2-2.42.2-2.2-2.22.42.5-2.42.42.4-2.00.3
Bone: maximum force3.46.88.12.7-2.72.7-2.82.6-2.6-2.62.72.8-2.82.82.8-2.50.3
Bone: maximum moment2.95.47.12.4-2.42.4-2.52.3-2.3-2.32.42.7-2.52.52.6-2.10.5
Mean time between licks in bursts0.10.40.6-0.70.7-0.70.7-0.70.70.7-0.7-0.60.7-0.7-0.70.80.2
Mean num. licks in bursts1.23.24.0-1.81.8-1.81.9-1.81.81.8-1.9-1.71.9-1.9-1.82.00.5
Cd content in liver1.11.31.61.3-1.31.3-1.21.2-1.2-1.21.21.0-1.21.21.1-1.1-0.1
Co content in liver0.40.51.1-0.50.5-0.50.6-0.50.50.5-0.6-0.90.8-0.8-0.90.5-1.1
Cu content in liver1.72.12.6-1.61.6-1.61.5-1.51.51.5-1.5-1.21.4-1.4-1.31.60.6
Fe content in liver0.70.81.6-0.70.7-0.70.9-0.70.70.7-0.9-1.31.1-1.1-1.20.6-1.1
K content in liver0.30.30.7-0.30.3-0.30.5-0.30.30.3-0.4-0.70.6-0.6-0.70.4-0.9
Mg content in liver0.91.01.4-1.01.0-1.01.1-1.01.01.0-1.1-1.01.2-1.2-1.21.1-0.2
Mn content in liver1.11.32.21.0-1.01.0-1.21.0-1.0-1.01.11.5-1.41.41.4-0.80.9
Na content in liver1.31.41.9-1.31.3-1.31.2-1.21.21.2-1.2-1.11.1-1.1-1.11.40.4
Rb content in liver5.05.86.7-2.52.5-2.52.6-2.52.52.5-2.6-2.62.6-2.6-2.62.2-0.3
Se content in liver2.32.73.81.5-1.51.5-1.71.6-1.6-1.61.71.9-1.91.92.0-1.70.6
Sr content in liver0.30.30.40.7-0.70.7-0.60.6-0.6-0.60.60.4-0.50.50.4-0.00.3
Zn content in liver0.10.10.20.2-0.20.2-0.30.2-0.2-0.20.30.4-0.20.20.30.10.4
Bone: minimum diameter0.00.10.5-0.10.1-0.10.1-0.20.20.2-0.20.20.1-0.1-0.00.40.7
Time in familiar zone, hab. session 10.91.06.8-1.01.0-1.00.6-1.01.01.0-0.60.20.2-0.20.11.02.6
Time in novel zone, hab. session 11.51.65.1-0.70.7-0.71.2-0.80.80.8-1.1-1.81.6-1.6-1.70.8-2.3
Total zone transitions, hab. session 10.00.00.00.1-0.10.1-0.10.1-0.1-0.10.10.1-0.00.00.00.20.0
Total locomotion distance, hab. session 10.40.61.90.5-0.50.5-0.70.4-0.4-0.40.71.1-0.80.81.0-0.11.4
Locomotion velocity, hab. session 11.52.13.61.4-1.41.4-1.51.3-1.3-1.31.61.9-1.71.71.8-1.01.0
Time in familiar zone, hab. session 20.91.03.2-1.21.2-1.20.9-1.11.11.1-0.9-0.30.6-0.6-0.41.11.8
Time in novel zone, hab. session 21.11.22.7-0.70.7-0.71.1-0.80.80.8-1.1-1.61.3-1.3-1.50.7-1.7
Total zone transitions, hab. session 20.70.92.21.0-1.01.0-0.91.1-1.1-1.10.90.5-0.70.70.6-0.9-1.5
Total locomotion distance, hab. session 20.81.11.31.1-1.11.1-1.11.1-1.1-1.11.11.0-1.11.11.1-1.0-0.4
Locomotion velocity, hab. session 21.01.41.71.2-1.21.2-1.31.2-1.2-1.21.31.3-1.21.21.2-1.1-0.3
Novel to familiar place preference ratio2.73.65.3-1.71.7-1.72.0-1.71.71.7-2.0-2.32.2-2.2-2.31.9-1.2
Novelty place preference3.84.86.6-2.12.1-2.12.4-2.12.12.1-2.3-2.62.5-2.5-2.62.2-0.9
Time in novel zone, NPP test4.85.98.1-2.32.3-2.32.6-2.32.32.3-2.6-2.82.7-2.7-2.82.4-1.0
Total zone transitions, NPP test0.81.22.31.2-1.21.2-1.11.3-1.3-1.31.10.6-0.80.80.7-1.1-1.5
Total locomotion distance, NPP test2.02.73.51.8-1.81.8-1.71.9-1.9-1.91.81.2-1.51.51.3-1.6-1.4
Locomotion velocity, NPP test2.53.54.32.0-2.02.0-2.02.1-2.1-2.12.01.6-1.71.71.7-1.8-1.1
Intraocular pressure2.33.85.12.3-2.32.3-2.02.0-2.0-2.02.01.7-1.81.81.7-2.3-0.7
Delta distance traveled before/after self-admin0.10.10.4-0.40.4-0.40.3-0.40.40.4-0.2-0.0-0.00.00.10.10.7
Delta ambulatory time before/after self-admin0.40.71.1-1.01.0-1.00.9-1.11.11.1-0.8-0.50.5-0.5-0.50.80.7
Parametrial fat weight0.10.21.30.1-0.10.10.10.1-0.1-0.1-0.1-0.40.4-0.4-0.50.1-1.2
Pavlov. Cond. lever latency7.29.110.4-3.13.1-3.13.2-3.23.23.2-3.2-2.83.1-3.1-3.03.21.1
Pavlov. Cond. magazine entry latency0.60.70.90.9-0.90.9-0.90.9-0.9-0.90.90.9-0.90.90.9-0.7-0.2
Pavlov. Cond. change in total contacts2.93.23.81.8-1.81.8-1.92.0-2.0-2.01.91.5-1.81.81.7-1.8-1.0
Pavlov. Cond. index score3.44.45.02.1-2.12.1-2.22.2-2.2-2.22.22.0-2.22.22.2-2.1-0.5
Pavlov. Cond. latency score3.14.04.62.0-2.02.0-2.12.1-2.1-2.12.11.9-2.12.12.0-2.1-0.6
Pavlov. Cond. lever contacts6.68.09.12.9-2.92.9-3.03.0-3.0-3.03.02.7-2.92.92.8-3.0-0.9
Pavlov. Cond. magazine entry number0.81.01.2-1.01.0-1.01.1-1.01.01.0-1.1-1.11.1-1.1-1.10.8-0.1
Pavlov. Cond. intertrial magazine entries0.20.20.30.4-0.40.4-0.50.5-0.5-0.50.50.5-0.50.50.6-0.50.2
Pavlov. Cond. lever-magazine prob. diff.3.44.24.82.0-2.02.0-2.22.1-2.1-2.12.22.1-2.22.22.2-2.0-0.2
Pavlov. Cond. response bias4.35.46.22.4-2.42.4-2.52.5-2.5-2.52.52.2-2.42.42.3-2.3-0.6
Pavlov. Cond. lever latency2.53.65.3-1.91.9-1.92.0-1.71.71.7-1.9-2.32.2-2.2-2.31.5-1.2
Pavlov. Cond. magazine entry latency0.20.31.0-0.60.6-0.60.5-0.50.50.5-0.5-0.20.3-0.3-0.20.51.0
Pavlov. Cond. change in total contacts0.61.44.70.8-0.80.8-1.10.7-0.7-0.71.11.7-1.41.41.6-0.42.2
Pavlov. Cond. index score0.30.52.60.4-0.40.4-0.60.3-0.3-0.30.51.1-0.80.81.0-0.11.6
Pavlov. Cond. latency score0.40.73.00.5-0.50.5-0.70.4-0.4-0.40.61.2-0.90.91.1-0.31.7
Pavlov. Cond. lever contacts1.82.74.21.6-1.61.6-1.71.4-1.4-1.41.72.1-1.91.92.0-1.21.2
Pavlov. Cond. magazine entry number0.30.43.5-0.10.1-0.10.4-0.10.10.1-0.3-0.90.7-0.7-0.80.0-1.9
Pavlov. Cond. intertrial magazine entries0.20.30.40.7-0.70.7-0.60.6-0.6-0.60.60.5-0.50.50.5-0.7-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.63.00.4-0.40.4-0.60.3-0.3-0.30.51.1-0.80.81.0-0.11.7
Pavlov. Cond. response bias1.01.42.51.0-1.01.0-1.10.9-0.9-0.91.11.6-1.41.41.5-0.61.6
Time in closed arm before self-admin0.30.50.9-0.60.6-0.60.8-1.01.01.0-0.8-0.50.8-0.8-0.80.50.2
Time in closed arm after self-admin0.20.20.6-0.60.6-0.60.3-0.40.40.4-0.30.20.2-0.2-0.00.70.8
Time in open arm before self-admin1.21.52.31.3-1.31.3-1.31.5-1.5-1.51.30.6-0.90.90.8-1.1-1.2
Time in open arm after self-admin0.80.91.41.2-1.21.2-0.81.0-1.0-1.00.90.3-0.70.70.5-1.2-1.0
Bone: periosteal estimation1.94.55.12.2-2.22.2-2.32.2-2.2-2.22.22.2-2.22.22.2-1.9-0.2
Bone: periosteal perimeter0.71.31.61.3-1.31.3-1.21.3-1.3-1.31.21.0-1.01.01.0-1.1-0.9
Bone: post-yield work2.23.74.52.1-2.12.1-2.02.1-2.1-2.12.01.6-1.81.81.7-1.9-1.3
Progressive ratio test 1 active lever presses0.30.62.6-0.60.6-0.60.9-0.60.60.6-0.7-1.60.8-0.8-1.0-0.2-0.6
Progressive ratio test 1 breakpoint0.30.52.2-0.50.5-0.50.8-0.40.40.4-0.6-1.50.7-0.7-0.8-0.3-0.6
Progressive ratio test 1 inactive lever presses0.41.02.31.2-1.21.2-0.81.1-1.1-1.10.9-0.0-0.60.60.4-1.3-1.5
Progressive ratio test 2 active lever presses0.71.03.3-0.70.7-0.71.2-0.90.90.9-1.0-1.81.1-1.1-1.2-0.3-0.7
Progressive ratio test 2 breakpoint0.91.13.5-0.80.8-0.81.2-1.01.01.0-1.0-1.91.1-1.1-1.3-0.2-0.7
Progressive ratio test 2 inactive lever presses0.00.10.90.3-0.30.3-0.10.1-0.1-0.10.2-0.1-0.20.20.1-0.9-0.3
Incentive Sensitization - Responses0.10.41.1-0.50.5-0.50.8-0.60.60.6-0.5-1.10.4-0.4-0.5-0.6-0.5
Incentive Sensitization - Breakpoint0.20.41.2-0.50.5-0.50.8-0.70.70.7-0.6-1.10.5-0.5-0.6-0.5-0.5
Sum of active levers in priming session hrs 5-63.23.05.6-1.61.6-1.61.7-1.31.31.3-1.7-2.42.1-2.1-2.21.6-1.2
Progressive ratio0.00.00.40.1-0.10.1-0.00.0-0.0-0.0-0.1-0.10.2-0.2-0.2-0.0-0.6
Food seeking constrained by brief footshock7.49.313.13.5-3.53.5-3.03.2-3.2-3.23.12.2-2.82.82.6-3.6-2.1
Seeking ratio, punishment vs. effort1.22.83.71.8-1.81.8-1.71.7-1.7-1.71.71.4-1.81.81.7-1.9-0.4
Retroperitoneal fat weight0.41.62.1-1.41.4-1.41.3-1.41.41.4-1.2-0.81.1-1.1-1.01.51.1
Reaction time number correct0.00.20.50.6-0.60.6-0.30.2-0.2-0.20.30.1-0.10.10.0-0.4-0.7
Reaction time mean minus median0.21.07.60.1-0.10.1-0.70.5-0.5-0.50.61.4-0.90.91.20.02.8
Reaction time mean minus median AUC0.21.54.70.8-0.80.8-1.20.9-0.9-0.91.11.7-1.31.31.5-0.52.2
Reaction time num false alarms0.10.11.30.1-0.10.1-0.0-0.20.20.2-0.00.4-0.30.30.40.01.1
Reaction time num false alarms AUC0.20.50.60.7-0.70.7-0.70.6-0.6-0.60.60.8-0.80.80.8-0.70.5
Reaction time trials correct on left0.00.20.50.6-0.60.6-0.30.2-0.2-0.20.30.1-0.10.10.0-0.4-0.7
Reaction time trials on left0.00.10.50.5-0.50.5-0.20.1-0.1-0.10.20.00.0-0.0-0.1-0.2-0.7
Reaction time mean0.81.85.3-1.71.7-1.71.1-1.31.31.3-1.2-0.40.9-0.9-0.71.62.3
Reaction time mean AUC0.92.26.3-1.81.8-1.81.2-1.41.41.4-1.3-0.51.0-1.0-0.71.72.5
Median of all reaction times2.23.55.0-2.22.2-2.21.8-1.91.91.9-1.9-1.31.6-1.6-1.52.01.6
Reaction time omissions1.42.43.2-1.81.8-1.81.5-1.31.31.3-1.6-1.51.6-1.6-1.61.70.3
Reaction time false alarm rate0.10.11.1-0.30.3-0.30.1-0.20.20.2-0.20.1-0.10.10.20.21.0
Reaction time premature initiation rate2.23.55.5-2.32.3-2.31.9-1.81.81.8-1.9-1.61.6-1.6-1.51.91.4
Reaction time premature initiations0.72.23.2-1.81.8-1.81.5-1.51.51.5-1.5-1.41.4-1.4-1.31.60.9
Std. dev. reaction times0.20.77.4-0.70.7-0.70.1-0.30.30.3-0.10.6-0.20.20.40.72.7
Reaction time trials completed0.00.10.50.5-0.50.5-0.20.1-0.1-0.10.20.00.0-0.0-0.1-0.2-0.7
Reaction time trials AUC0.00.10.40.5-0.50.5-0.20.1-0.1-0.10.20.10.0-0.0-0.1-0.2-0.6
Run reversals in cocaine runway, females0.20.21.20.2-0.20.20.0-0.50.50.5-0.20.60.0-0.00.00.51.1
Run reversals in cocaine runway, males0.10.10.2-0.40.4-0.40.4-0.30.30.3-0.4-0.40.3-0.3-0.30.30.2
Latency to leave start box in cocaine runway0.60.81.10.8-0.80.8-1.01.0-1.0-1.01.00.9-1.11.11.1-0.70.0
Latency to leave start box in cocaine runway, F0.10.10.5-0.20.2-0.20.2-0.10.10.1-0.2-0.40.3-0.3-0.30.3-0.7
Latency to leave start box in cocaine runway, M2.72.63.21.5-1.51.5-1.71.7-1.7-1.71.71.4-1.81.81.8-1.7-0.1
Std. dev. time between licks in bursts0.20.50.6-0.70.7-0.70.7-0.80.80.8-0.7-0.50.7-0.7-0.60.70.4
Total sessions with >9 infusions0.10.20.90.2-0.20.20.10.3-0.3-0.30.2-0.90.0-0.0-0.2-1.0-0.7
Short access day 1 total inactive lever presses0.61.22.81.1-1.11.1-0.91.3-1.3-1.31.10.0-0.80.80.6-1.4-1.7
Short access day 10 total inactive lever presses0.21.11.60.8-0.80.8-1.11.1-1.1-1.11.21.0-1.21.21.2-0.9-0.4
Short access day 1 total infusions0.20.41.50.3-0.30.3-0.10.6-0.6-0.60.4-0.9-0.10.1-0.1-1.2-1.2
Short access day 10 total infusions0.10.21.10.1-0.10.10.30.1-0.1-0.1-0.1-1.00.5-0.5-0.7-0.3-1.0
Short access total infusions0.30.42.1-0.20.2-0.20.6-0.20.20.2-0.3-1.50.5-0.5-0.7-0.6-1.0
Short access day 1 locomotion0.81.43.7-1.11.1-1.11.2-0.80.80.8-1.1-1.91.4-1.4-1.50.9-0.4
Short access day 10 total locomotion0.41.41.9-1.21.2-1.21.2-1.41.41.4-1.2-0.91.1-1.1-1.01.21.2
Short access total locomotion0.30.41.3-0.50.5-0.50.7-0.40.40.4-0.6-1.20.9-0.9-1.00.6-0.0
One hour access (0.3 mA shock)0.10.10.40.6-0.60.6-0.10.1-0.1-0.10.1-0.10.1-0.1-0.2-0.6-0.6
Compulsive drug intake0.10.21.00.5-0.50.5-0.40.0-0.0-0.00.31.0-0.40.40.5-0.10.5
One hour access (shock baseline)0.10.31.90.3-0.30.30.20.2-0.2-0.2-0.1-0.90.3-0.3-0.5-0.6-1.4
Social response proportion1.92.33.4-1.81.8-1.81.5-1.61.61.6-1.5-1.21.5-1.5-1.41.60.6
Social responses0.70.91.11.0-1.01.0-1.00.9-0.9-0.91.01.0-1.01.01.0-1.0-0.3
Social time0.00.10.5-0.20.2-0.20.1-0.00.00.0-0.1-0.20.2-0.2-0.20.0-0.7
Soleus weight0.30.87.40.6-0.60.6-0.20.8-0.8-0.80.3-0.80.4-0.4-0.6-0.5-2.7
Bone: stiffness4.58.29.42.9-2.92.9-3.02.9-2.9-2.93.03.1-3.13.13.1-2.80.2
Tibialis anterior weight8.830.335.35.9-5.95.9-5.85.9-5.9-5.95.84.9-5.45.45.2-5.6-2.0
Time to tail flick, vehicle, before self-admin0.70.81.6-0.70.7-0.70.8-1.11.11.1-1.0-0.40.9-0.9-0.91.30.4
Time to tail flick, vehicle, after self-admin0.00.00.3-0.10.1-0.1-0.10.0-0.0-0.00.10.2-0.20.20.2-0.10.5
Time to tail flick, test, before self-admin0.30.40.60.8-0.80.8-0.60.3-0.3-0.30.60.8-0.60.60.6-0.7-0.0
Time to tail flick, test, after self-admin1.71.84.21.4-1.41.4-1.50.9-0.9-0.91.42.0-1.41.51.6-0.91.2
Delta time to tail flick, vehicle, before/after SA0.30.30.70.2-0.20.2-0.50.6-0.6-0.60.60.4-0.70.70.6-0.8-0.1
Delta time to tail flick, test, before/after SA0.10.10.7-0.20.2-0.20.0-0.20.20.2-0.10.3-0.00.00.20.40.8
Tibia length0.10.42.50.7-0.70.7-0.30.5-0.5-0.50.3-0.1-0.10.1-0.1-0.6-1.6
Ambulatory time before self-admin1.64.77.52.1-2.12.1-2.22.7-2.7-2.72.41.3-2.02.01.9-2.3-1.4
Ambulatory time after self-admin0.60.91.40.7-0.70.7-1.01.2-1.2-1.21.10.7-1.11.11.1-0.9-0.4
Bone: tissue strength0.20.20.20.4-0.40.4-0.50.4-0.4-0.40.40.5-0.50.50.5-0.4-0.0
Total heroin consumption1.01.24.1-0.90.9-0.91.1-0.60.60.6-1.0-2.01.3-1.3-1.50.6-0.7
Bone: trabecular number0.81.62.61.2-1.21.2-1.31.1-1.1-1.11.31.6-1.41.41.5-0.90.9
Bone: trabecular spacing0.00.00.2-0.20.2-0.2-0.0-0.00.00.00.00.1-0.20.20.2-0.10.5
Bone: trabecular thickness0.20.30.6-0.50.5-0.50.5-0.60.60.6-0.5-0.20.4-0.4-0.30.80.8
Bone: trabecular tissue density3.05.36.22.4-2.42.4-2.42.4-2.4-2.42.42.2-2.42.42.4-2.5-0.3
Water consumed over 24 hours0.61.11.71.0-1.01.0-1.11.0-1.0-1.01.11.1-1.21.21.2-1.3-0.0
Number of responses in last shaping day0.60.75.70.1-0.10.10.20.5-0.5-0.5-0.0-1.50.6-0.6-0.8-0.6-2.4