Hub : Genes

Spata31f3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative TSS XM_006238096.5 0.02 0.02 1.1e-03 0.01 0 0.01 0.01 1.9e-03 4.7e-02 8.4e-03 9.2e-03
2 NAcc gene expression Spata31f3 0.03 0.02 1.6e-04 0.02 0.01 0.01 0.01 4.2e-04 6.6e-03 3.8e-03 6.8e-03
3 NAcc alternative TSS XM_006238096.5 0.02 0.01 6.7e-03 0.01 0 0 0 1.8e-02 1.7e-01 1.5e-01 1.1e-01
4 PL alternative TSS NM_001024343.2 0.03 0.02 2.0e-03 0.02 0.02 0.02 0.02 4.3e-03 6.4e-03 3.4e-03 3.5e-03
5 PL alternative TSS XM_006238096.5 0.03 0.02 1.7e-03 0.02 0.01 0.01 0.01 4.8e-03 4.2e-02 8.8e-03 7.2e-03
6 PL alternative TSS XM_039110562.2 0.03 0.02 4.7e-04 0.02 0.01 0.02 0.02 2.2e-03 1.2e-02 3.7e-03 2.9e-03
7 PL gene expression Spata31f3 0.06 0.06 4.5e-05 0.04 0.03 0.03 0.04 9.8e-06 6.9e-04 1.8e-04 3.9e-05
8 PL alternative TSS XM_006238096.5 0.02 0.02 3.3e-03 0.02 0.01 0.02 0.02 6.8e-03 1.3e-02 5.5e-03 6.7e-03
9 IC alternative TSS XM_006238096.5 0.11 0.07 7.9e-04 0.05 0.04 0.03 0.04 4.7e-03 6.3e-03 1.4e-02 1.3e-02
10 IC alternative TSS XM_006238096.5 0.1 0.07 2.7e-03 0.04 0.05 0.04 0.04 1.3e-02 3.7e-03 8.5e-03 1.1e-02
11 IC alternative TSS NM_001024343.2 0.1 0.07 2.8e-03 0.04 0.05 0.04 0.04 1.3e-02 3.7e-03 9.3e-03 1.1e-02
12 IC alternative TSS XM_039110562.2 0.1 0.07 1.3e-03 0.04 0.04 0.03 0.03 1.3e-02 1.1e-02 2.8e-02 2.4e-02
13 BLA gene expression Spata31f3 0.07 0.05 4.1e-03 0.03 0.02 0.03 0.02 8.2e-03 2.2e-02 1.4e-02 2.1e-02
14 Brain gene expression Spata31f3 0.04 0.03 6.6e-03 0.03 0.02 0.03 0.02 1.0e-03 4.1e-03 5.0e-04 2.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density1.22.13.2-1.41.4-1.41.5-1.31.31.3-1.5-1.8-1.61.61.71.1-1.0
Area under the delay curve0.50.61.00.7-0.70.7-0.80.6-0.6-0.60.71.01.0-1.0-1.0-0.80.4
BMI with tail1.55.26.3-2.32.3-2.32.4-2.32.32.3-2.4-2.5-2.42.42.52.1-0.3
BMI without tail2.37.18.1-2.82.8-2.82.8-2.72.72.7-2.8-2.8-2.82.82.82.60.0
Body weight3.415.018.7-4.34.3-4.34.0-4.14.14.1-4.0-3.6-3.73.73.63.81.4
Weight adjusted by age0.20.21.5-0.50.5-0.50.4-0.50.50.5-0.3-0.1-0.20.20.10.31.2
Bone surface0.81.51.9-1.41.4-1.41.3-1.21.21.2-1.3-1.3-1.21.21.21.00.1
Bone volume0.71.21.7-1.11.1-1.11.2-1.01.01.0-1.2-1.3-1.21.21.20.8-0.4
Breakpoint value in progressive ratio session1.01.25.10.2-0.20.2-0.6-0.10.10.10.62.01.3-1.3-1.6-0.22.2
Number of licking bursts3.96.47.9-2.42.4-2.42.7-2.52.52.5-2.7-2.6-2.82.82.82.8-0.1
Context. condit. distance diff. score0.10.10.20.4-0.40.4-0.40.4-0.4-0.40.40.30.3-0.3-0.3-0.4-0.4
Locomotion velocity, session 11.41.511.7-1.11.1-1.10.6-1.11.11.1-0.70.5-0.00.0-0.31.13.4
Locomotion distance, session 10.50.73.8-0.80.8-0.80.6-0.90.90.9-0.70.0-0.30.30.10.71.9
Locomotion velocity, session 22.22.53.7-1.61.6-1.61.7-1.51.51.5-1.7-1.9-1.71.71.81.4-0.4
Locomotion distance, session 22.53.44.3-2.12.1-2.11.9-2.02.02.0-2.0-1.5-1.71.71.51.81.5
Locomotion velocity, session 30.20.32.1-0.40.4-0.40.2-0.50.50.5-0.20.40.0-0.0-0.20.61.4
Locomotion distance, session 32.42.63.4-1.81.8-1.81.7-1.81.81.8-1.7-1.2-1.41.41.31.71.2
Stereotopy head waving bouts, day 30.20.21.60.1-0.10.1-0.30.1-0.1-0.10.30.80.4-0.4-0.6-0.01.3
Stereotopy head waving duration, day 30.30.30.80.5-0.50.5-0.60.5-0.5-0.50.70.90.5-0.5-0.6-0.40.5
Locomotion velocity, session 70.10.10.10.3-0.30.3-0.30.3-0.3-0.30.30.30.3-0.3-0.3-0.3-0.0
Locomotion distance, session 70.30.30.5-0.70.7-0.70.6-0.60.60.6-0.6-0.4-0.40.40.40.60.6
Stereotopy head waving bouts, day 71.11.31.8-1.21.2-1.21.2-1.31.31.3-1.1-0.8-1.11.11.01.30.6
Stereotopy head waving duration, day 70.60.71.0-0.80.8-0.80.8-0.90.90.9-0.8-0.6-0.90.90.81.00.3
Locomotion velocity, session 80.20.22.0-0.40.4-0.40.1-0.30.30.3-0.10.20.1-0.1-0.20.41.4
Locomotion distance, session 80.30.41.6-0.70.7-0.70.5-0.70.70.7-0.6-0.2-0.30.30.20.61.2
Degree of sensitization distance1.11.11.41.1-1.11.1-1.11.2-1.2-1.21.11.01.0-1.0-1.0-1.1-0.5
Degree of sensitization stereotypy1.31.41.6-1.21.2-1.21.3-1.31.31.3-1.2-1.1-1.31.31.21.30.0
Conditioned locomotion0.10.21.6-0.00.0-0.0-0.1-0.20.20.20.00.50.2-0.2-0.30.21.2
Cocaine response after cond. corrected1.62.03.61.2-1.21.2-1.41.1-1.1-1.11.41.91.6-1.6-1.8-0.91.6
Cocaine response after cond. not corrected1.41.63.71.0-1.01.0-1.20.9-0.9-0.91.21.81.4-1.5-1.6-0.81.9
Cocaine response before conditioning0.81.01.2-1.01.0-1.01.1-1.01.01.0-1.1-1.0-1.11.11.10.9-0.1
Saline control response1.11.42.0-1.31.3-1.31.1-1.31.31.3-1.2-0.6-1.01.00.81.41.4
Bone: connectivity density0.50.81.6-0.80.8-0.80.9-0.70.70.7-0.9-1.3-1.01.01.10.5-1.1
Bone: cortical apparent density0.20.21.90.3-0.30.30.00.2-0.2-0.2-0.0-0.5-0.30.30.5-0.1-1.4
Bone: cortical area2.94.46.7-2.02.0-2.02.2-2.02.02.0-2.2-2.6-2.42.42.51.7-1.1
Bone: cortical porosity0.30.30.40.5-0.50.5-0.60.6-0.6-0.60.60.40.5-0.5-0.5-0.5-0.5
Bone: cortical porosity0.00.00.00.0-0.00.0-0.10.1-0.1-0.10.10.10.1-0.1-0.10.0-0.0
Bone: cortical thickness1.01.73.4-1.01.0-1.01.3-1.01.01.0-1.2-1.8-1.61.61.70.8-1.8
Bone: cortical thickness0.20.31.80.5-0.50.5-0.30.5-0.5-0.50.30.00.2-0.2-0.0-0.7-1.3
Bone: cortical tissue density0.10.21.60.3-0.30.3-0.10.2-0.2-0.20.1-0.4-0.20.20.3-0.1-1.3
Condit. Reinf. active minus inactive responses0.40.50.7-0.60.6-0.60.8-0.80.80.8-0.8-0.7-0.80.80.80.70.0
Condit. Reinf. active-inactive response ratio0.70.71.01.0-1.01.0-0.80.9-0.9-0.90.90.80.8-0.8-0.7-0.9-0.4
Condit. Reinf. active responses2.73.44.2-1.71.7-1.72.0-1.91.91.9-2.0-2.0-2.02.02.11.70.0
Condit. Reinf. inactive responses3.54.26.0-2.12.1-2.12.2-2.02.02.0-2.2-2.4-2.32.32.31.8-0.4
Incentive salience index mean4.45.46.2-2.32.3-2.32.5-2.52.52.5-2.5-2.2-2.42.42.42.30.7
Condit. Reinf. lever presses10.715.017.2-4.14.1-4.14.1-4.14.14.1-4.1-3.5-3.83.83.74.01.8
Condit. Reinf. active minus inactive responses0.81.01.5-1.11.1-1.11.0-0.90.90.9-1.0-1.2-1.01.01.10.9-0.4
Condit. Reinf. active-inactive response ratio0.10.10.5-0.40.4-0.40.3-0.20.20.2-0.3-0.7-0.30.30.40.1-0.6
Condit. Reinf. active responses2.63.64.3-2.12.1-2.12.0-1.91.91.9-2.0-2.0-1.91.91.91.7-0.1
Condit. Reinf. inactive responses3.14.05.3-2.02.0-2.02.1-2.02.02.0-2.1-2.1-2.32.32.31.9-0.6
Condit. Reinf. lever presses2.83.95.9-1.91.9-1.92.1-1.71.71.7-2.0-2.4-2.32.32.41.6-1.4
Condit. Reinf. lever reinforcers received2.94.15.0-2.22.2-2.22.1-2.02.02.0-2.1-2.2-2.12.12.11.9-0.1
Conditioned reinforcement - actives0.00.10.6-0.10.1-0.1-0.20.2-0.2-0.2-0.00.2-0.10.10.00.7-0.4
Conditioned reinforcement - inactives0.20.30.80.5-0.50.5-0.70.7-0.7-0.70.60.90.4-0.4-0.50.00.1
Conditioned locomotion0.00.00.3-0.20.2-0.20.0-0.10.10.1-0.20.4-0.00.0-0.10.50.2
Patch foraging indifference point 0 sec0.50.97.8-0.90.9-0.90.4-0.70.70.7-0.40.50.0-0.0-0.30.72.8
Patch foraging indifference point AUC7.711.214.1-3.83.8-3.83.5-3.53.53.5-3.5-3.4-3.23.23.13.31.0
Delay disc. indifference point, 0s delay1.01.01.81.0-1.01.0-1.10.9-0.9-0.91.11.31.2-1.2-1.3-0.80.5
Delay disc. indifference point, 16s delay0.91.02.50.8-0.80.8-1.00.5-0.5-0.50.91.61.3-1.3-1.4-0.81.2
Delay disc. indifference point, 2s delay0.10.10.5-0.00.0-0.00.1-0.00.00.0-0.2-0.4-0.30.30.4-0.0-0.7
Delay disc. indifference point, 24s delay0.10.10.40.4-0.40.4-0.30.1-0.1-0.10.30.30.4-0.4-0.4-0.6-0.0
Delay disc. indifference point, 4s delay0.10.10.20.3-0.30.3-0.30.3-0.3-0.30.30.40.4-0.4-0.4-0.4-0.1
Delay disc. indifference point, 8s delay0.00.00.0-0.10.1-0.10.1-0.00.00.0-0.1-0.1-0.00.00.00.1-0.0
Indifference point function ln k2.34.05.12.3-2.32.3-2.12.0-2.0-2.02.12.22.0-2.0-1.9-1.9-0.3
Indifference point function log k2.34.05.12.3-2.32.3-2.12.0-2.0-2.02.12.22.0-2.0-1.9-1.9-0.3
Patch foraging total patch changes 0 sec0.71.37.0-1.21.2-1.20.8-1.11.11.1-0.80.1-0.40.40.21.12.6
Patch foraging total patch changes 12 sec2.02.53.0-1.71.7-1.71.7-1.71.71.7-1.7-1.6-1.51.51.51.70.6
Patch foraging total patch changes 18 sec0.81.21.8-1.31.3-1.31.1-1.11.11.1-1.1-1.0-0.80.80.71.01.0
Patch foraging total patch changes 24 sec1.83.14.5-2.12.1-2.11.8-1.81.81.8-1.8-1.6-1.51.51.41.71.3
Patch foraging total patch changes 6 sec2.64.05.3-2.32.3-2.32.0-2.22.22.2-2.0-1.3-1.51.51.42.12.3
Patch foraging time to switch 0 sec2.04.16.02.4-2.42.4-2.12.1-2.1-2.12.11.81.8-1.8-1.7-1.8-1.5
Patch foraging water rate 0 sec1.32.73.7-1.91.9-1.91.6-1.71.71.7-1.6-1.1-1.31.31.21.61.8
Patch foraging water rate 12 sec0.00.00.3-0.30.3-0.30.1-0.20.20.2-0.10.1-0.00.0-0.0-0.10.6
Patch foraging water rate 18 sec0.30.51.2-0.50.5-0.50.6-0.50.50.5-0.6-0.8-0.80.80.90.4-1.1
Patch foraging water rate 24 sec0.10.21.70.3-0.30.3-0.20.4-0.4-0.40.2-0.3-0.10.10.2-0.5-1.3
Patch foraging water rate 6 sec0.81.11.6-1.01.0-1.01.0-1.01.01.0-1.1-0.9-1.31.31.21.20.0
Seeking ratio, delayed vs. immediate footshock3.44.15.3-1.81.8-1.82.2-2.32.32.3-2.2-1.8-2.22.22.22.20.3
Distance traveled before self-admin4.86.39.6-2.42.4-2.42.6-3.13.13.1-2.7-1.6-2.42.42.32.51.3
Distance traveled after self-admin1.82.23.8-1.11.1-1.11.5-1.51.51.5-1.7-1.4-1.91.92.01.5-0.7
Extensor digitorum longus weight5.321.023.6-4.84.8-4.84.8-4.94.94.9-4.8-4.4-4.74.74.64.61.0
Bone: elastic displacement6.17.09.02.8-2.82.8-2.72.9-2.9-2.92.82.22.6-2.6-2.5-3.0-1.2
Bone: elastic work2.63.47.92.0-2.02.0-1.72.0-2.0-2.01.80.71.3-1.3-1.0-2.1-2.8
Bone: endosteal estimation1.32.93.6-1.91.9-1.91.7-1.91.91.9-1.7-1.4-1.51.51.41.71.3
Bone: endosteal perimeter1.32.83.6-1.91.9-1.91.7-1.91.91.9-1.8-1.2-1.51.51.31.61.4
Epididymis fat weight0.41.21.9-1.11.1-1.11.2-1.11.11.1-1.1-1.4-1.21.21.20.9-0.1
Delta time in closed arm before/after self-admin0.50.51.2-0.40.4-0.40.8-0.60.60.6-0.7-1.1-0.80.80.9-0.0-0.8
Delta time in open arm before/after self-admin0.30.30.90.4-0.40.4-0.70.5-0.5-0.50.60.90.6-0.6-0.70.10.5
Diff in mean of infusions in LGA sessions0.10.11.00.4-0.40.4-0.20.3-0.3-0.30.3-0.00.0-0.00.0-0.1-1.0
Delay discount exponential model param0.40.50.9-0.60.6-0.60.7-0.50.50.5-0.6-0.9-0.90.90.90.7-0.4
Extinction: sum of active levers before priming3.13.45.92.1-2.12.1-1.91.5-1.5-1.51.82.42.0-2.0-2.0-1.70.0
Active lever presses in extinction session 60.30.30.60.5-0.50.5-0.40.2-0.2-0.20.50.70.8-0.8-0.8-0.7-0.1
Bone: final force2.13.44.2-1.91.9-1.91.9-1.81.81.8-1.9-2.0-2.02.02.01.7-0.3
Bone: final moment1.72.73.8-1.71.7-1.71.7-1.61.61.6-1.7-2.0-1.81.81.81.5-0.5
Food consumed during 24 hour testing period0.91.31.7-1.21.2-1.21.2-1.21.21.2-1.2-1.0-1.11.11.01.30.9
Glucose2.64.15.2-2.32.3-2.32.2-2.12.12.1-2.1-2.1-2.02.01.92.00.7
Heart weight0.81.21.7-1.21.2-1.21.2-1.31.31.3-1.2-1.2-1.01.01.00.70.1
Delay discount hyperbolic model param0.30.30.6-0.40.4-0.40.5-0.40.40.4-0.5-0.7-0.70.70.80.5-0.4
Intermittent access intake day 1-15 change0.50.91.5-0.70.7-0.71.0-1.01.01.0-1.0-1.1-1.21.21.20.9-0.1
Intermittent access intake escalation0.40.81.5-0.60.6-0.60.9-0.90.90.9-0.9-1.0-1.21.21.20.7-0.4
Intermittent access intake escalation 21.11.32.7-0.60.6-0.61.1-0.90.90.9-1.1-1.4-1.61.61.71.2-1.1
Intermitt. access day 1 inactive lever presses0.51.92.7-1.41.4-1.41.5-1.61.61.6-1.5-1.1-1.31.31.21.20.9
Intermitt. access day 15 inactive lever presses0.10.10.3-0.10.1-0.10.2-0.50.50.5-0.30.1-0.40.40.40.40.3
Intermitt. access escalation Index0.50.71.2-0.90.9-0.90.9-1.11.11.1-0.8-0.5-0.70.70.70.80.2
Intermittent access day 1 total infusions1.52.44.71.3-1.31.3-1.71.5-1.5-1.51.62.21.9-1.9-2.0-1.00.3
Intermittent access day 15 total infusions0.00.00.30.1-0.10.1-0.10.1-0.1-0.1-0.00.1-0.10.10.10.2-0.5
Intermittent access terminal intake (last 3 days)0.10.10.9-0.00.0-0.00.0-0.10.10.1-0.20.2-0.30.30.30.9-0.2
Intermittent access total infusions0.00.10.5-0.00.0-0.0-0.20.2-0.2-0.20.00.40.0-0.0-0.10.70.1
Intermittent access day 1 locomotion1.62.03.31.1-1.11.1-1.51.4-1.4-1.41.51.81.8-1.8-1.8-1.10.3
Intermittent access day 15 total locomotion0.91.72.41.0-1.01.0-1.41.4-1.4-1.41.41.51.5-1.5-1.5-1.20.2
Intermittent access total locomotion1.92.33.21.4-1.41.4-1.71.8-1.8-1.81.61.51.5-1.5-1.4-1.3-0.7
Intermittent access standard deviation0.20.40.8-0.40.4-0.40.5-0.70.70.7-0.7-0.3-0.70.70.60.90.4
Left kidney weight0.73.24.6-2.12.1-2.11.8-2.02.02.0-1.7-1.2-1.41.41.21.62.1
Right kidney weight0.42.03.0-1.71.7-1.71.5-1.51.51.5-1.3-1.5-1.21.21.11.00.8
Cocaine induced anxiety0.10.10.20.4-0.40.4-0.40.5-0.5-0.50.30.30.1-0.1-0.10.20.3
Post-drug Anxiety0.70.81.8-1.01.0-1.00.8-0.70.70.7-0.9-0.6-0.80.80.81.30.9
Baseline Anxiety0.70.81.1-0.90.9-0.91.1-1.01.01.0-1.0-1.0-0.90.90.90.8-0.2
Tail length2.18.310.0-3.23.2-3.23.1-3.03.03.0-3.0-2.9-2.82.82.82.80.7
Length with tail1.87.710.3-3.23.2-3.22.8-3.13.13.1-2.8-2.1-2.32.32.12.72.1
Length without tail0.10.42.6-0.50.5-0.50.3-0.80.80.8-0.40.40.0-0.0-0.20.51.6
Times rat made contact with spout0.40.40.7-0.50.5-0.50.7-0.60.60.6-0.7-0.7-0.80.80.90.8-0.5
Lifetime Intake0.10.10.7-0.10.1-0.1-0.20.1-0.1-0.10.00.70.1-0.1-0.30.80.5
Liver weight, left0.00.00.4-0.00.0-0.0-0.0-0.00.00.00.10.20.2-0.2-0.3-0.20.6
Liver weight, right0.71.31.71.3-1.31.3-1.31.3-1.3-1.31.21.01.0-1.0-0.9-0.9-0.8
Locomotor activity0.00.00.1-0.00.0-0.00.1-0.10.10.1-0.10.0-0.10.10.10.0-0.3
Locomotor testing distance0.10.20.70.3-0.30.3-0.40.3-0.3-0.30.40.90.5-0.5-0.6-0.30.7
Locomotor testing rearing0.61.11.9-1.11.1-1.11.0-1.01.01.0-1.1-0.7-1.21.21.11.40.5
Locomotion in novel chamber0.30.40.70.7-0.70.7-0.70.9-0.9-0.90.70.10.5-0.5-0.4-0.6-0.6
Locomotion in novel chamber post-restriction0.91.53.7-1.11.1-1.11.2-0.70.70.7-1.2-1.9-1.51.51.70.9-1.2
Fecal boli incidents, locomotor time 10.91.31.91.3-1.31.3-1.11.2-1.2-1.21.20.81.2-1.2-1.1-1.4-0.3
Change in fecal boli incidents, locomotor task0.80.81.1-1.11.1-1.10.9-1.01.01.0-0.9-0.4-0.70.70.60.90.9
Time >=10cm from walls, locomotor time 10.20.20.5-0.50.5-0.50.3-0.60.60.6-0.30.20.0-0.0-0.10.60.7
Bouts of movement, locomotor time 11.92.22.81.7-1.71.7-1.61.6-1.6-1.61.51.41.4-1.4-1.3-1.6-0.4
Total resting periods, locomotor time 12.62.93.71.9-1.91.9-1.81.9-1.9-1.91.81.41.5-1.5-1.4-1.9-0.9
Rest time, locomotor task time 11.82.25.11.7-1.71.7-1.31.7-1.7-1.71.30.20.9-0.9-0.6-1.9-2.3
Distance moved, locomotor task time 11.92.84.2-1.91.9-1.91.6-2.02.02.0-1.6-0.6-1.21.21.02.01.9
Vertical activity count, locomotor time 10.71.64.5-1.31.3-1.31.0-1.41.41.4-1.00.1-0.70.70.51.72.1
Time >=10cm from walls, locomotor time 20.10.10.5-0.30.3-0.30.3-0.40.40.4-0.3-0.1-0.20.20.10.40.7
Bouts of movement, locomotor time 20.30.50.9-0.70.7-0.70.6-0.60.60.6-0.7-0.7-0.80.80.80.90.2
Total resting periods, locomotor time 20.10.10.2-0.30.3-0.30.2-0.10.10.1-0.3-0.3-0.50.50.50.5-0.0
Rest time, locomotor task time 21.01.32.01.1-1.11.1-1.21.4-1.4-1.41.10.70.9-0.9-0.8-1.4-1.0
Distance moved, locomotor task time 20.50.61.0-0.50.5-0.50.8-0.80.80.8-0.8-0.9-1.01.01.00.8-0.3
Vertical activity count, locomotor time 20.50.71.1-0.80.8-0.80.8-1.01.01.0-0.8-0.5-0.80.80.71.00.8
Light reinforcement 11.12.79.0-1.71.7-1.71.3-1.91.91.9-1.4-0.0-0.90.90.62.03.0
Light reinforcement 20.81.28.2-1.01.0-1.00.5-1.11.11.1-0.60.70.0-0.0-0.31.22.9
Bone: marrow area1.43.03.7-1.91.9-1.91.8-1.91.91.9-1.8-1.5-1.61.61.51.71.0
Bone: maximum diameter2.74.96.1-2.22.2-2.22.4-2.22.22.2-2.4-2.5-2.42.42.42.0-0.3
Bone: maximum force3.86.88.1-2.72.7-2.72.8-2.62.62.6-2.7-2.8-2.82.82.82.5-0.3
Bone: maximum moment3.15.47.1-2.42.4-2.42.5-2.32.32.3-2.4-2.7-2.52.52.62.1-0.5
Mean time between licks in bursts0.20.40.60.7-0.70.7-0.70.7-0.7-0.70.70.60.7-0.7-0.7-0.8-0.2
Mean num. licks in bursts2.03.24.01.8-1.81.8-1.91.8-1.8-1.81.91.71.9-1.9-1.8-2.0-0.5
Cd content in liver1.11.31.6-1.31.3-1.31.2-1.21.21.2-1.2-1.0-1.21.21.11.10.1
Co content in liver0.40.51.10.5-0.50.5-0.60.5-0.5-0.50.60.90.8-0.8-0.9-0.51.1
Cu content in liver1.72.12.61.6-1.61.6-1.51.5-1.5-1.51.51.21.4-1.4-1.3-1.6-0.6
Fe content in liver0.70.81.60.7-0.70.7-0.90.7-0.7-0.70.91.31.1-1.1-1.2-0.61.1
K content in liver0.30.30.70.3-0.30.3-0.50.3-0.3-0.30.40.70.6-0.6-0.7-0.40.9
Mg content in liver1.01.01.41.0-1.01.0-1.11.0-1.0-1.01.11.01.2-1.2-1.2-1.10.2
Mn content in liver1.11.32.2-1.01.0-1.01.2-1.01.01.0-1.1-1.5-1.41.41.40.8-0.9
Na content in liver1.31.41.91.3-1.31.3-1.21.2-1.2-1.21.21.11.1-1.1-1.1-1.4-0.4
Rb content in liver5.05.86.72.5-2.52.5-2.62.5-2.5-2.52.62.62.6-2.6-2.6-2.20.3
Se content in liver2.32.73.8-1.51.5-1.51.7-1.61.61.6-1.7-1.9-1.91.92.01.7-0.6
Sr content in liver0.30.30.4-0.70.7-0.70.6-0.60.60.6-0.6-0.4-0.50.50.40.0-0.3
Zn content in liver0.10.10.2-0.20.2-0.20.3-0.20.20.2-0.3-0.4-0.20.20.3-0.1-0.4
Bone: minimum diameter0.00.10.50.1-0.10.1-0.10.2-0.2-0.20.2-0.20.1-0.1-0.0-0.4-0.7
Time in familiar zone, hab. session 11.11.06.81.0-1.01.0-0.61.0-1.0-1.00.6-0.20.2-0.20.1-1.0-2.6
Time in novel zone, hab. session 11.61.65.10.7-0.70.7-1.20.8-0.8-0.81.11.81.6-1.6-1.7-0.82.3
Total zone transitions, hab. session 10.00.00.0-0.10.1-0.10.1-0.10.10.1-0.1-0.1-0.00.00.0-0.2-0.0
Total locomotion distance, hab. session 10.40.61.9-0.50.5-0.50.7-0.40.40.4-0.7-1.1-0.80.81.00.1-1.4
Locomotion velocity, hab. session 11.52.13.6-1.41.4-1.41.5-1.31.31.3-1.6-1.9-1.71.71.81.0-1.0
Time in familiar zone, hab. session 21.01.03.21.2-1.21.2-0.91.1-1.1-1.10.90.30.6-0.6-0.4-1.1-1.8
Time in novel zone, hab. session 21.21.22.70.7-0.70.7-1.10.8-0.8-0.81.11.61.3-1.3-1.5-0.71.7
Total zone transitions, hab. session 20.70.92.2-1.01.0-1.00.9-1.11.11.1-0.9-0.5-0.70.70.60.91.5
Total locomotion distance, hab. session 20.81.11.3-1.11.1-1.11.1-1.11.11.1-1.1-1.0-1.11.11.11.00.4
Locomotion velocity, hab. session 21.01.41.7-1.21.2-1.21.3-1.21.21.2-1.3-1.3-1.21.21.21.10.3
Novel to familiar place preference ratio3.33.65.31.7-1.71.7-2.01.7-1.7-1.72.02.32.2-2.2-2.3-1.91.2
Novelty place preference4.54.86.62.1-2.12.1-2.42.1-2.1-2.12.32.62.5-2.5-2.6-2.20.9
Time in novel zone, NPP test5.55.98.12.3-2.32.3-2.62.3-2.3-2.32.62.82.7-2.7-2.8-2.41.0
Total zone transitions, NPP test0.91.22.3-1.21.2-1.21.1-1.31.31.3-1.1-0.6-0.80.80.71.11.5
Total locomotion distance, NPP test2.02.73.5-1.81.8-1.81.7-1.91.91.9-1.8-1.2-1.51.51.31.61.4
Locomotion velocity, NPP test2.53.54.3-2.02.0-2.02.0-2.12.12.1-2.0-1.6-1.71.71.71.81.1
Intraocular pressure2.73.85.1-2.32.3-2.32.0-2.02.02.0-2.0-1.7-1.81.81.72.30.7
Delta distance traveled before/after self-admin0.10.10.40.4-0.40.4-0.30.4-0.4-0.40.20.0-0.00.00.1-0.1-0.7
Delta ambulatory time before/after self-admin0.60.71.11.0-1.01.0-0.91.1-1.1-1.10.80.50.5-0.5-0.5-0.8-0.7
Parametrial fat weight0.10.21.3-0.10.1-0.1-0.1-0.10.10.10.10.40.4-0.4-0.5-0.11.2
Pavlov. Cond. lever latency7.39.110.43.1-3.13.1-3.23.2-3.2-3.23.22.83.1-3.1-3.0-3.2-1.1
Pavlov. Cond. magazine entry latency0.60.70.9-0.90.9-0.90.9-0.90.90.9-0.9-0.9-0.90.90.90.70.2
Pavlov. Cond. change in total contacts3.03.23.8-1.81.8-1.81.9-2.02.02.0-1.9-1.5-1.81.81.71.81.0
Pavlov. Cond. index score3.54.45.0-2.12.1-2.12.2-2.22.22.2-2.2-2.0-2.22.22.22.10.5
Pavlov. Cond. latency score3.24.04.6-2.02.0-2.02.1-2.12.12.1-2.1-1.9-2.12.12.02.10.6
Pavlov. Cond. lever contacts6.78.09.1-2.92.9-2.93.0-3.03.03.0-3.0-2.7-2.92.92.83.00.9
Pavlov. Cond. magazine entry number0.81.01.21.0-1.01.0-1.11.0-1.0-1.01.11.11.1-1.1-1.1-0.80.1
Pavlov. Cond. intertrial magazine entries0.20.20.3-0.40.4-0.40.5-0.50.50.5-0.5-0.5-0.50.50.60.5-0.2
Pavlov. Cond. lever-magazine prob. diff.3.44.24.8-2.02.0-2.02.2-2.12.12.1-2.2-2.1-2.22.22.22.00.2
Pavlov. Cond. response bias4.45.46.2-2.42.4-2.42.5-2.52.52.5-2.5-2.2-2.42.42.32.30.6
Pavlov. Cond. lever latency2.63.65.31.9-1.91.9-2.01.7-1.7-1.71.92.32.2-2.2-2.3-1.51.2
Pavlov. Cond. magazine entry latency0.20.31.00.6-0.60.6-0.50.5-0.5-0.50.50.20.3-0.3-0.2-0.5-1.0
Pavlov. Cond. change in total contacts0.91.44.7-0.80.8-0.81.1-0.70.70.7-1.1-1.7-1.41.41.60.4-2.2
Pavlov. Cond. index score0.40.52.6-0.40.4-0.40.6-0.30.30.3-0.5-1.1-0.80.81.00.1-1.6
Pavlov. Cond. latency score0.50.73.0-0.50.5-0.50.7-0.40.40.4-0.6-1.2-0.90.91.10.3-1.7
Pavlov. Cond. lever contacts1.92.74.2-1.61.6-1.61.7-1.41.41.4-1.7-2.1-1.91.92.01.2-1.2
Pavlov. Cond. magazine entry number0.40.43.50.1-0.10.1-0.40.1-0.1-0.10.30.90.7-0.7-0.8-0.01.9
Pavlov. Cond. intertrial magazine entries0.20.30.4-0.70.7-0.70.6-0.60.60.6-0.6-0.5-0.50.50.50.70.5
Pavlov. Cond. lever-magazine prob. diff.0.40.63.0-0.40.4-0.40.6-0.30.30.3-0.5-1.1-0.80.81.00.1-1.7
Pavlov. Cond. response bias1.01.42.5-1.01.0-1.01.1-0.90.90.9-1.1-1.6-1.41.41.50.6-1.6
Time in closed arm before self-admin0.40.50.90.6-0.60.6-0.81.0-1.0-1.00.80.50.8-0.8-0.8-0.5-0.2
Time in closed arm after self-admin0.20.20.60.6-0.60.6-0.30.4-0.4-0.40.3-0.20.2-0.2-0.0-0.7-0.8
Time in open arm before self-admin1.41.52.3-1.31.3-1.31.3-1.51.51.5-1.3-0.6-0.90.90.81.11.2
Time in open arm after self-admin0.80.91.4-1.21.2-1.20.8-1.01.01.0-0.9-0.3-0.70.70.51.21.0
Bone: periosteal estimation2.14.55.1-2.22.2-2.22.3-2.22.22.2-2.2-2.2-2.22.22.21.90.2
Bone: periosteal perimeter0.81.31.6-1.31.3-1.31.2-1.31.31.3-1.2-1.0-1.01.01.01.10.9
Bone: post-yield work2.53.74.5-2.12.1-2.12.0-2.12.12.1-2.0-1.6-1.81.81.71.91.3
Progressive ratio test 1 active lever presses0.50.62.60.6-0.60.6-0.90.6-0.6-0.60.71.60.8-0.8-1.00.20.6
Progressive ratio test 1 breakpoint0.40.52.20.5-0.50.5-0.80.4-0.4-0.40.61.50.7-0.7-0.80.30.6
Progressive ratio test 1 inactive lever presses0.71.02.3-1.21.2-1.20.8-1.11.11.1-0.90.0-0.60.60.41.31.5
Progressive ratio test 2 active lever presses0.91.03.30.7-0.70.7-1.20.9-0.9-0.91.01.81.1-1.1-1.20.30.7
Progressive ratio test 2 breakpoint1.01.13.50.8-0.80.8-1.21.0-1.0-1.01.01.91.1-1.1-1.30.20.7
Progressive ratio test 2 inactive lever presses0.10.10.9-0.30.3-0.30.1-0.10.10.1-0.20.1-0.20.20.10.90.3
Incentive Sensitization - Responses0.30.41.10.5-0.50.5-0.80.6-0.6-0.60.51.10.4-0.4-0.50.60.5
Incentive Sensitization - Breakpoint0.30.41.20.5-0.50.5-0.80.7-0.7-0.70.61.10.5-0.5-0.60.50.5
Sum of active levers in priming session hrs 5-63.23.05.61.6-1.61.6-1.71.3-1.3-1.31.72.42.1-2.1-2.2-1.61.2
Progressive ratio0.00.00.4-0.10.1-0.10.0-0.00.00.00.10.10.2-0.2-0.20.00.6
Food seeking constrained by brief footshock7.69.313.1-3.53.5-3.53.0-3.23.23.2-3.1-2.2-2.82.82.63.62.1
Seeking ratio, punishment vs. effort1.92.83.7-1.81.8-1.81.7-1.71.71.7-1.7-1.4-1.81.81.71.90.4
Retroperitoneal fat weight0.41.62.11.4-1.41.4-1.31.4-1.4-1.41.20.81.1-1.1-1.0-1.5-1.1
Reaction time number correct0.10.20.5-0.60.6-0.60.3-0.20.20.2-0.3-0.1-0.10.10.00.40.7
Reaction time mean minus median0.41.07.6-0.10.1-0.10.7-0.50.50.5-0.6-1.4-0.90.91.2-0.0-2.8
Reaction time mean minus median AUC0.61.54.7-0.80.8-0.81.2-0.90.90.9-1.1-1.7-1.31.31.50.5-2.2
Reaction time num false alarms0.10.11.3-0.10.1-0.10.00.2-0.2-0.20.0-0.4-0.30.30.4-0.0-1.1
Reaction time num false alarms AUC0.30.50.6-0.70.7-0.70.7-0.60.60.6-0.6-0.8-0.80.80.80.7-0.5
Reaction time trials correct on left0.10.20.5-0.60.6-0.60.3-0.20.20.2-0.3-0.1-0.10.10.00.40.7
Reaction time trials on left0.10.10.5-0.50.5-0.50.2-0.10.10.1-0.2-0.00.0-0.0-0.10.20.7
Reaction time mean1.21.85.31.7-1.71.7-1.11.3-1.3-1.31.20.40.9-0.9-0.7-1.6-2.3
Reaction time mean AUC1.42.26.31.8-1.81.8-1.21.4-1.4-1.41.30.51.0-1.0-0.7-1.7-2.5
Median of all reaction times2.43.55.02.2-2.22.2-1.81.9-1.9-1.91.91.31.6-1.6-1.5-2.0-1.6
Reaction time omissions1.62.43.21.8-1.81.8-1.51.3-1.3-1.31.61.51.6-1.6-1.6-1.7-0.3
Reaction time false alarm rate0.10.11.10.3-0.30.3-0.10.2-0.2-0.20.2-0.1-0.10.10.2-0.2-1.0
Reaction time premature initiation rate2.53.55.52.3-2.32.3-1.91.8-1.8-1.81.91.61.6-1.6-1.5-1.9-1.4
Reaction time premature initiations1.32.23.21.8-1.81.8-1.51.5-1.5-1.51.51.41.4-1.4-1.3-1.6-0.9
Std. dev. reaction times0.40.77.40.7-0.70.7-0.10.3-0.3-0.30.1-0.6-0.20.20.4-0.7-2.7
Reaction time trials completed0.10.10.5-0.50.5-0.50.2-0.10.10.1-0.2-0.00.0-0.0-0.10.20.7
Reaction time trials AUC0.10.10.4-0.50.5-0.50.2-0.10.10.1-0.2-0.10.0-0.0-0.10.20.6
Run reversals in cocaine runway, females0.20.21.2-0.20.2-0.2-0.00.5-0.5-0.50.2-0.60.0-0.00.0-0.5-1.1
Run reversals in cocaine runway, males0.10.10.20.4-0.40.4-0.40.3-0.3-0.30.40.40.3-0.3-0.3-0.3-0.2
Latency to leave start box in cocaine runway0.70.81.1-0.80.8-0.81.0-1.01.01.0-1.0-0.9-1.11.11.10.7-0.0
Latency to leave start box in cocaine runway, F0.10.10.50.2-0.20.2-0.20.1-0.1-0.10.20.40.3-0.3-0.3-0.30.7
Latency to leave start box in cocaine runway, M2.82.63.2-1.51.5-1.51.7-1.71.71.7-1.7-1.4-1.81.81.81.70.1
Std. dev. time between licks in bursts0.30.50.60.7-0.70.7-0.70.8-0.8-0.80.70.50.7-0.7-0.6-0.7-0.4
Total sessions with >9 infusions0.20.20.9-0.20.2-0.2-0.1-0.30.30.3-0.20.90.0-0.0-0.21.00.7
Short access day 1 total inactive lever presses0.91.22.8-1.11.1-1.10.9-1.31.31.3-1.1-0.0-0.80.80.61.41.7
Short access day 10 total inactive lever presses0.41.11.6-0.80.8-0.81.1-1.11.11.1-1.2-1.0-1.21.21.20.90.4
Short access day 1 total infusions0.30.41.5-0.30.3-0.30.1-0.60.60.6-0.40.9-0.10.1-0.11.21.2
Short access day 10 total infusions0.20.21.1-0.10.1-0.1-0.3-0.10.10.10.11.00.5-0.5-0.70.31.0
Short access total infusions0.30.42.10.2-0.20.2-0.60.2-0.2-0.20.31.50.5-0.5-0.70.61.0
Short access day 1 locomotion1.11.43.71.1-1.11.1-1.20.8-0.8-0.81.11.91.4-1.4-1.5-0.90.4
Short access day 10 total locomotion0.81.41.91.2-1.21.2-1.21.4-1.4-1.41.20.91.1-1.1-1.0-1.2-1.2
Short access total locomotion0.40.41.30.5-0.50.5-0.70.4-0.4-0.40.61.20.9-0.9-1.0-0.60.0
One hour access (0.3 mA shock)0.10.10.4-0.60.6-0.60.1-0.10.10.1-0.10.10.1-0.1-0.20.60.6
Compulsive drug intake0.20.21.0-0.50.5-0.50.4-0.00.00.0-0.3-1.0-0.40.40.50.1-0.5
One hour access (shock baseline)0.20.31.9-0.30.3-0.3-0.2-0.20.20.20.10.90.3-0.3-0.50.61.4
Social response proportion2.12.33.41.8-1.81.8-1.51.6-1.6-1.61.51.21.5-1.5-1.4-1.6-0.6
Social responses0.70.91.1-1.01.0-1.01.0-0.90.90.9-1.0-1.0-1.01.01.01.00.3
Social time0.00.10.50.2-0.20.2-0.10.0-0.0-0.00.10.20.2-0.2-0.2-0.00.7
Soleus weight0.30.87.4-0.60.6-0.60.2-0.80.80.8-0.30.80.4-0.4-0.60.52.7
Bone: stiffness5.18.29.4-2.92.9-2.93.0-2.92.92.9-3.0-3.1-3.13.13.12.8-0.2
Tibialis anterior weight9.030.335.3-5.95.9-5.95.8-5.95.95.9-5.8-4.9-5.45.45.25.62.0
Time to tail flick, vehicle, before self-admin0.80.81.60.7-0.70.7-0.81.1-1.1-1.11.00.40.9-0.9-0.9-1.3-0.4
Time to tail flick, vehicle, after self-admin0.00.00.30.1-0.10.10.1-0.00.00.0-0.1-0.2-0.20.20.20.1-0.5
Time to tail flick, test, before self-admin0.30.40.6-0.80.8-0.80.6-0.30.30.3-0.6-0.8-0.60.60.60.70.0
Time to tail flick, test, after self-admin1.81.84.2-1.41.4-1.41.5-0.90.90.9-1.4-2.0-1.41.51.60.9-1.2
Delta time to tail flick, vehicle, before/after SA0.30.30.7-0.20.2-0.20.5-0.60.60.6-0.6-0.4-0.70.70.60.80.1
Delta time to tail flick, test, before/after SA0.10.10.70.2-0.20.2-0.00.2-0.2-0.20.1-0.3-0.00.00.2-0.4-0.8
Tibia length0.10.42.5-0.70.7-0.70.3-0.50.50.5-0.30.1-0.10.1-0.10.61.6
Ambulatory time before self-admin3.24.77.5-2.12.1-2.12.2-2.72.72.7-2.4-1.3-2.02.01.92.31.4
Ambulatory time after self-admin0.80.91.4-0.70.7-0.71.0-1.21.21.2-1.1-0.7-1.11.11.10.90.4
Bone: tissue strength0.20.20.2-0.40.4-0.40.5-0.40.40.4-0.4-0.5-0.50.50.50.40.0
Total heroin consumption1.01.24.10.9-0.90.9-1.10.6-0.6-0.61.02.01.3-1.3-1.5-0.60.7
Bone: trabecular number1.01.62.6-1.21.2-1.21.3-1.11.11.1-1.3-1.6-1.41.41.50.9-0.9
Bone: trabecular spacing0.00.00.20.2-0.20.20.00.0-0.0-0.0-0.0-0.1-0.20.20.20.1-0.5
Bone: trabecular thickness0.20.30.60.5-0.50.5-0.50.6-0.6-0.60.50.20.4-0.4-0.3-0.8-0.8
Bone: trabecular tissue density3.65.36.2-2.42.4-2.42.4-2.42.42.4-2.4-2.2-2.42.42.42.50.3
Water consumed over 24 hours0.81.11.7-1.01.0-1.01.1-1.01.01.0-1.1-1.1-1.21.21.21.30.0
Number of responses in last shaping day0.70.75.7-0.10.1-0.1-0.2-0.50.50.50.01.50.6-0.6-0.80.62.4