Sp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Sp2 0.08 0.06 1.3e-03 0.05 0.05 0.02 0.04 9.1e-04 1.6e-03 1.9e-02 2.7e-03
2 Liver mRNA stability Sp2 0.06 0.04 6.0e-11 0.09 0.09 0.1 0.1 4.0e-10 1.9e-10 1.1e-10 1.1e-10
3 pVTA isoform ratio NM_001399622.1 0.07 0.06 8.4e-03 -0 0.01 -0 -0 3.5e-01 6.8e-02 6.4e-01 3.5e-01
4 pVTA alternative TSS XM_039086079.1 0.06 0.05 5.8e-03 0.06 0.04 0.06 0.05 1.2e-03 1.1e-02 1.4e-03 3.7e-03
5 pVTA alternative TSS XM_039086080.1 0.09 0.07 7.2e-04 0.09 0.06 0.05 0.07 1.5e-04 1.4e-03 2.9e-03 4.5e-04
6 Liver gene expression Sp2 0.05 0.03 1.2e-09 0.07 0.08 0.08 0.08 5.7e-08 1.5e-09 1.3e-09 1.6e-09
7 pVTA alternative TSS NM_001399622.1 0.05 0.04 7.0e-03 0 0.01 -0.01 -0 1.9e-01 7.4e-02 7.2e-01 4.8e-01
8 Brain alternative TSS XM_039086080.1 0.02 0.02 6.3e-03 0.01 0.02 0.01 0.02 1.6e-02 5.9e-03 5.1e-02 1.2e-02
9 Brain alternative TSS XM_039086079.1 0.02 0.02 8.8e-03 0.01 0.02 0.01 0.01 1.7e-02 7.0e-03 5.7e-02 2.4e-02
10 Adipose gene expression Sp2 0.02 0.01 2.2e-03 0.02 0.02 0.01 0.01 4.1e-03 2.8e-03 6.9e-03 8.7e-03
11 PL gene expression Sp2 0.1 0.06 9.5e-13 0.1 0.12 0.12 0.11 1.3e-11 8.4e-13 1.0e-12 6.0e-12
12 Adipose alternative TSS XM_039086078.1 0.21 0.11 0.0e+00 0.27 0.28 0.28 0.28 1.6e-29 2.1e-31 6.4e-31 2.7e-31
13 IL gene expression Sp2 0.37 0.23 6.9e-04 0.04 0.06 -0.01 0.03 4.9e-02 1.4e-02 7.2e-01 6.5e-02
14 pVTA gene expression Sp2 0.14 0.09 8.5e-06 0.11 0.1 0.06 0.09 1.3e-05 2.9e-05 9.1e-04 8.1e-05
15 NAcc gene expression Sp2 0.04 0.03 3.9e-06 0.05 0.04 0.05 0.05 1.4e-06 1.6e-05 3.4e-06 2.3e-06
16 Brain gene expression Sp2 0.07 0.05 4.3e-06 0.07 0.06 0.06 0.07 2.2e-07 3.7e-06 3.7e-06 4.3e-07
17 Brain alternative TSS NM_001399622.1 0.03 0.02 5.0e-04 0.04 0.02 0.03 0.02 2.0e-04 2.8e-03 1.6e-03 2.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density1.62.73.3-1.7-1.7-1.81.4-1.4-1.3-1.81.6-1.61.51.81.61.8-1.7-1.7-1.71.7
Area under the delay curve0.40.41.20.30.60.4-1.11.10.80.5-0.70.7-0.6-0.4-0.4-0.20.40.40.60.1
BMI with tail10.433.742.1-6.5-6.3-5.04.3-4.3-5.9-5.65.9-6.16.25.86.15.8-6.1-6.1-6.06.0
BMI without tail1.12.33.4-1.6-1.5-1.20.4-0.4-1.4-1.41.4-1.51.61.71.71.8-1.8-1.8-1.71.7
Body weight0.31.45.2-1.5-0.90.9-2.32.3-0.20.10.1-0.61.00.71.11.1-1.2-1.2-1.20.6
Weight adjusted by age0.80.91.31.11.01.0-0.70.70.71.0-0.90.9-1.0-1.0-1.0-1.11.11.11.1-0.9
Bone surface0.30.51.0-1.0-0.8-0.40.0-0.0-0.3-0.50.5-0.60.60.70.70.8-0.9-0.9-0.90.8
Bone volume1.01.72.5-1.6-1.4-1.10.6-0.6-1.0-1.21.2-1.31.31.41.41.5-1.5-1.5-1.51.5
Breakpoint value in progressive ratio session4.65.15.82.22.22.4-1.91.92.32.4-2.42.4-2.4-2.4-2.4-2.42.32.32.3-1.7
Number of licking bursts0.10.10.20.40.3-0.10.5-0.50.20.0-0.10.2-0.2-0.2-0.3-0.20.30.30.3-0.2
Context. condit. distance diff. score0.20.20.5-0.4-0.4-0.2-0.00.0-0.4-0.30.4-0.40.50.40.50.4-0.7-0.7-0.60.6
Locomotion velocity, session 10.40.40.6-0.7-0.7-0.40.5-0.5-0.7-0.60.7-0.70.80.60.70.6-0.7-0.7-0.80.6
Locomotion distance, session 13.03.95.41.71.82.3-2.02.01.92.2-2.01.9-1.8-2.0-1.8-1.91.91.91.9-2.2
Locomotion velocity, session 21.31.53.41.01.11.4-1.91.91.31.3-1.31.2-1.1-1.1-1.0-0.80.90.90.9-1.1
Locomotion distance, session 23.44.75.91.92.12.3-2.22.22.22.3-2.32.2-2.1-2.2-2.1-2.02.12.12.2-2.4
Locomotion velocity, session 30.10.10.40.00.10.3-0.60.60.30.3-0.30.3-0.2-0.2-0.2-0.10.30.30.2-0.4
Locomotion distance, session 33.64.04.71.82.02.1-2.12.12.22.1-2.12.0-1.9-2.0-1.9-1.81.91.91.8-2.1
Stereotopy head waving bouts, day 34.95.87.4-2.4-2.5-2.72.0-2.0-2.5-2.62.4-2.42.32.62.42.6-2.3-2.3-2.42.5
Stereotopy head waving duration, day 33.23.94.5-2.1-2.1-2.01.4-1.4-2.1-2.12.0-2.02.02.12.12.1-1.9-1.9-2.02.0
Locomotion velocity, session 71.81.92.31.21.31.5-1.51.51.41.4-1.51.4-1.3-1.4-1.3-1.31.31.31.5-1.5
Locomotion distance, session 75.26.77.82.52.72.5-2.62.62.82.6-2.72.7-2.6-2.5-2.5-2.42.42.42.5-2.7
Stereotopy head waving bouts, day 70.80.91.4-0.9-1.0-1.11.2-1.2-1.1-1.01.0-0.90.90.90.80.8-0.7-0.7-0.61.0
Stereotopy head waving duration, day 70.40.51.3-0.6-0.7-0.71.1-1.1-0.9-0.70.7-0.70.60.50.50.4-0.3-0.3-0.30.7
Locomotion velocity, session 80.10.10.5-0.3-0.20.7-0.50.5-0.00.3-0.0-0.10.2-0.10.1-0.1-0.3-0.3-0.20.1
Locomotion distance, session 80.91.42.61.01.11.5-1.61.61.11.3-1.21.1-1.0-1.1-1.0-1.00.80.81.0-1.2
Degree of sensitization distance0.00.00.10.00.00.2-0.30.30.10.2-0.20.1-0.1-0.1-0.1-0.10.10.10.2-0.1
Degree of sensitization stereotypy0.10.20.90.2-0.0-0.41.0-1.0-0.2-0.20.2-0.0-0.1-0.1-0.2-0.30.40.40.50.1
Conditioned locomotion0.91.11.7-1.1-1.0-1.00.4-0.4-1.0-1.01.0-1.01.11.21.21.3-1.3-1.3-1.21.1
Cocaine response after cond. corrected5.76.48.9-2.4-2.4-2.51.2-1.2-2.4-2.62.4-2.52.52.82.83.0-2.9-2.9-2.72.7
Cocaine response after cond. not corrected3.33.66.1-1.8-1.8-2.00.6-0.6-1.7-2.01.7-1.81.82.22.22.5-2.2-2.2-2.02.0
Cocaine response before conditioning2.12.53.11.61.61.2-1.21.21.71.5-1.61.7-1.7-1.5-1.6-1.51.81.81.7-1.7
Saline control response0.10.20.50.30.30.10.0-0.00.30.3-0.40.4-0.5-0.4-0.5-0.50.60.60.7-0.5
Bone: connectivity density0.30.40.9-0.5-0.5-0.91.0-1.0-0.3-0.70.6-0.50.40.60.50.6-0.5-0.5-0.50.7
Bone: cortical apparent density4.66.110.33.22.91.6-0.20.22.42.1-2.32.6-2.8-2.6-2.9-2.82.92.92.7-2.5
Bone: cortical area0.00.10.2-0.4-0.3-0.1-0.50.50.1-0.20.0-0.10.10.30.30.4-0.2-0.2-0.30.1
Bone: cortical porosity0.50.60.9-0.8-0.7-1.00.5-0.5-0.7-0.90.8-0.80.80.90.80.9-0.7-0.7-0.60.6
Bone: cortical porosity0.40.40.8-0.7-0.6-0.90.2-0.2-0.6-0.80.6-0.60.70.80.80.9-0.6-0.6-0.50.4
Bone: cortical thickness0.20.30.50.60.60.3-0.70.70.70.4-0.60.7-0.7-0.4-0.5-0.30.60.60.6-0.7
Bone: cortical thickness0.91.11.81.11.10.5-1.31.31.30.8-1.21.2-1.2-0.7-0.9-0.51.01.01.0-1.1
Bone: cortical tissue density4.96.410.93.33.01.6-0.20.22.52.2-2.32.6-2.8-2.6-2.9-2.92.92.92.8-2.5
Condit. Reinf. active minus inactive responses0.10.10.10.30.30.00.2-0.20.30.1-0.20.3-0.3-0.2-0.3-0.30.30.30.2-0.1
Condit. Reinf. active-inactive response ratio0.30.40.7-0.5-0.6-0.80.8-0.8-0.6-0.70.6-0.50.50.60.50.5-0.4-0.4-0.50.7
Condit. Reinf. active responses0.00.00.20.20.2-0.10.5-0.50.2-0.0-0.10.1-0.2-0.1-0.2-0.20.20.20.1-0.1
Condit. Reinf. inactive responses0.20.20.30.60.60.20.2-0.20.60.3-0.40.5-0.5-0.5-0.5-0.50.50.50.3-0.6
Incentive salience index mean0.10.20.30.60.50.00.3-0.30.40.2-0.30.4-0.5-0.3-0.5-0.40.60.60.5-0.4
Condit. Reinf. lever presses0.60.81.51.10.90.40.2-0.20.70.7-0.70.9-0.9-0.9-1.0-1.01.21.21.2-1.1
Condit. Reinf. active minus inactive responses0.20.20.5-0.4-0.4-0.70.7-0.7-0.5-0.60.5-0.50.50.50.40.5-0.4-0.4-0.10.2
Condit. Reinf. active-inactive response ratio0.70.71.7-0.6-0.8-1.01.3-1.3-0.9-0.90.9-0.80.80.70.70.6-0.6-0.6-0.40.5
Condit. Reinf. active responses0.10.10.3-0.1-0.1-0.60.6-0.6-0.2-0.40.2-0.20.10.30.20.2-0.1-0.10.1-0.1
Condit. Reinf. inactive responses0.10.20.30.40.4-0.10.1-0.10.30.1-0.30.4-0.5-0.3-0.4-0.30.60.60.5-0.5
Condit. Reinf. lever presses0.60.81.31.11.10.7-0.30.30.80.8-0.80.9-0.9-0.9-0.9-0.91.01.01.1-1.1
Condit. Reinf. lever reinforcers received0.00.10.20.20.1-0.30.4-0.40.1-0.10.00.1-0.10.0-0.1-0.00.20.20.4-0.4
Conditioned reinforcement - actives1.81.82.8-0.9-1.0-1.71.5-1.5-1.4-1.51.4-1.31.31.41.31.4-1.1-1.1-1.21.2
Conditioned reinforcement - inactives0.40.51.20.30.3-0.00.5-0.50.40.3-0.40.6-0.7-0.6-0.8-0.81.01.01.1-0.9
Conditioned locomotion4.65.57.2-1.9-2.1-2.72.0-2.0-2.5-2.62.5-2.52.52.62.52.6-2.2-2.2-2.32.1
Patch foraging indifference point 0 sec1.01.62.7-1.1-1.2-1.50.5-0.5-1.3-1.41.2-1.21.31.51.41.6-1.2-1.2-1.31.3
Patch foraging indifference point AUC0.10.20.40.40.30.50.2-0.20.30.4-0.30.4-0.4-0.5-0.5-0.70.40.40.5-0.2
Delay disc. indifference point, 0s delay0.91.01.60.80.90.7-0.90.91.00.9-1.01.1-1.1-0.9-1.0-0.91.21.21.3-0.6
Delay disc. indifference point, 16s delay0.30.30.8-0.7-0.4-0.4-0.40.4-0.2-0.50.3-0.40.40.70.70.9-0.7-0.7-0.70.4
Delay disc. indifference point, 2s delay0.40.41.20.20.50.2-1.11.10.60.4-0.70.7-0.6-0.3-0.4-0.10.80.80.8-0.4
Delay disc. indifference point, 24s delay0.40.40.90.60.80.7-0.80.81.00.7-0.70.7-0.6-0.5-0.5-0.40.30.30.3-0.0
Delay disc. indifference point, 4s delay4.14.47.51.62.12.0-2.72.72.42.1-2.42.3-2.2-1.9-1.9-1.51.91.92.1-1.1
Delay disc. indifference point, 8s delay0.10.10.20.30.40.1-0.40.40.50.2-0.30.3-0.3-0.1-0.20.00.10.10.20.5
Indifference point function ln k0.10.10.50.20.2-0.1-0.70.70.2-0.1-0.0-0.10.10.20.30.4-0.3-0.3-0.3-0.1
Indifference point function log k0.10.10.50.20.2-0.1-0.70.70.2-0.1-0.0-0.10.10.20.30.4-0.3-0.3-0.3-0.1
Patch foraging total patch changes 0 sec0.91.52.6-1.2-1.2-1.30.2-0.2-1.2-1.31.1-1.21.21.51.41.6-1.2-1.2-1.31.3
Patch foraging total patch changes 12 sec0.40.61.5-0.4-0.5-1.20.9-0.9-0.6-1.00.8-0.70.60.90.70.9-0.6-0.6-0.60.8
Patch foraging total patch changes 18 sec1.62.02.4-1.4-1.5-1.51.6-1.6-1.5-1.51.5-1.51.51.41.41.3-1.2-1.2-1.11.2
Patch foraging total patch changes 24 sec1.72.02.9-1.6-1.6-1.61.1-1.1-1.6-1.51.4-1.41.41.51.41.5-1.2-1.2-1.31.7
Patch foraging total patch changes 6 sec1.11.62.2-1.0-1.0-1.51.4-1.4-1.2-1.41.3-1.31.31.41.31.3-1.2-1.2-1.11.1
Patch foraging time to switch 0 sec0.10.20.6-0.3-0.4-0.50.8-0.8-0.4-0.50.5-0.40.40.40.40.3-0.3-0.3-0.40.4
Patch foraging water rate 0 sec0.40.71.3-1.1-0.9-0.4-0.50.5-0.7-0.60.6-0.70.80.91.01.1-1.0-1.0-0.90.9
Patch foraging water rate 12 sec0.30.41.60.30.50.8-1.21.20.80.7-0.70.6-0.5-0.5-0.4-0.20.40.40.4-0.6
Patch foraging water rate 18 sec0.70.91.60.70.70.7-1.31.30.90.8-1.11.0-1.0-0.8-0.8-0.61.01.01.1-0.9
Patch foraging water rate 24 sec0.50.61.2-0.9-0.8-0.90.1-0.1-0.7-0.90.7-0.80.81.01.01.1-0.9-0.9-0.70.7
Patch foraging water rate 6 sec0.00.10.3-0.1-0.0-0.0-0.10.10.10.1-0.20.2-0.3-0.2-0.2-0.20.30.30.5-0.3
Seeking ratio, delayed vs. immediate footshock0.30.40.8-0.5-0.5-0.50.7-0.7-0.4-0.60.7-0.60.60.60.60.5-0.8-0.8-0.90.0
Distance traveled before self-admin0.50.51.10.70.70.7-0.50.50.70.8-0.80.8-0.8-0.7-0.8-0.70.80.81.0-0.4
Distance traveled after self-admin1.01.11.9-0.9-0.9-0.70.3-0.3-1.0-0.91.0-1.11.21.11.31.3-1.3-1.3-1.21.4
Extensor digitorum longus weight0.10.52.2-0.5-0.11.5-1.41.40.30.7-0.2-0.10.4-0.30.2-0.1-0.6-0.6-0.3-0.2
Bone: elastic displacement0.10.20.3-0.3-0.4-0.50.2-0.2-0.5-0.50.4-0.40.50.50.50.5-0.4-0.4-0.30.3
Bone: elastic work0.10.10.40.00.10.1-0.60.60.10.0-0.1-0.00.10.20.20.4-0.2-0.2-0.1-0.2
Bone: endosteal estimation0.30.61.1-1.0-0.70.1-0.90.9-0.3-0.30.4-0.60.70.60.80.8-1.0-1.0-1.00.8
Bone: endosteal perimeter0.30.71.6-1.3-1.1-0.2-0.30.3-0.6-0.50.6-0.80.90.70.90.9-1.1-1.1-1.11.0
Epididymis fat weight0.10.10.8-0.20.10.4-0.90.90.30.2-0.20.1-0.0-0.00.10.10.00.0-0.0-0.4
Delta time in closed arm before/after self-admin0.10.10.50.30.50.7-0.30.30.50.5-0.30.2-0.1-0.4-0.2-0.30.10.1-0.10.5
Delta time in open arm before/after self-admin0.20.20.50.40.30.20.3-0.30.10.3-0.30.4-0.4-0.5-0.5-0.60.40.40.7-0.5
Diff in mean of infusions in LGA sessions0.50.51.10.60.60.60.1-0.10.80.7-0.60.7-0.8-0.9-0.9-1.01.01.00.8-0.1
Delay discount exponential model param0.50.61.9-0.4-0.8-0.61.4-1.4-1.0-0.70.9-0.80.70.50.50.2-0.5-0.5-0.6-0.1
Extinction: sum of active levers before priming1.11.11.71.31.31.2-1.31.31.11.1-1.11.0-1.0-1.0-0.9-0.90.80.80.9-0.7
Active lever presses in extinction session 60.20.20.6-0.4-0.4-0.40.6-0.6-0.3-0.40.4-0.40.40.40.40.4-0.5-0.5-0.40.8
Bone: final force0.20.40.9-0.7-0.6-0.80.0-0.0-0.3-0.70.5-0.50.50.80.70.9-0.6-0.6-0.60.4
Bone: final moment0.30.41.0-0.8-0.7-0.8-0.10.1-0.4-0.70.5-0.60.60.90.81.0-0.7-0.7-0.60.5
Food consumed during 24 hour testing period1.41.72.11.41.41.5-0.90.91.31.4-1.31.3-1.3-1.4-1.3-1.41.21.21.2-1.2
Glucose0.40.61.6-0.9-0.7-0.7-0.40.4-0.5-0.70.5-0.60.71.01.01.2-0.9-0.9-0.70.5
Heart weight0.81.13.4-1.8-1.5-0.4-0.00.0-1.1-0.70.9-1.01.10.91.11.0-1.2-1.2-1.11.1
Delay discount hyperbolic model param0.80.92.4-0.6-1.0-0.81.5-1.5-1.2-0.81.1-1.00.90.60.70.4-0.7-0.7-0.90.2
Intermittent access intake day 1-15 change2.02.03.1-1.8-1.6-1.40.9-0.9-1.6-1.51.4-1.51.51.51.51.6-1.4-1.4-1.31.2
Intermittent access intake escalation2.22.23.4-1.9-1.7-1.51.0-1.0-1.7-1.51.5-1.51.61.61.61.6-1.4-1.4-1.31.3
Intermittent access intake escalation 21.41.42.8-1.7-1.5-1.00.8-0.8-1.3-1.11.2-1.31.31.21.31.2-1.1-1.1-1.11.0
Intermitt. access day 1 inactive lever presses0.30.30.70.10.20.00.5-0.50.60.3-0.40.5-0.6-0.5-0.6-0.60.70.70.8-0.8
Intermitt. access day 15 inactive lever presses1.01.14.9-0.8-0.9-1.32.2-2.2-0.9-1.01.0-0.80.60.70.40.3-0.4-0.4-0.50.8
Intermitt. access escalation Index2.21.93.7-1.0-1.0-1.00.4-0.4-1.2-1.21.3-1.41.51.51.61.6-1.8-1.8-1.71.9
Intermittent access day 1 total infusions0.20.20.90.90.80.2-0.10.10.60.3-0.40.4-0.4-0.3-0.4-0.30.40.40.3-0.2
Intermittent access day 15 total infusions0.30.30.5-0.4-0.4-0.70.5-0.5-0.6-0.60.6-0.60.60.60.60.6-0.5-0.5-0.50.6
Intermittent access terminal intake (last 3 days)0.30.30.7-0.4-0.4-0.70.8-0.8-0.6-0.60.6-0.60.50.50.50.5-0.4-0.4-0.40.6
Intermittent access total infusions0.00.00.10.10.1-0.20.1-0.1-0.1-0.20.1-0.10.10.20.20.2-0.1-0.1-0.10.3
Intermittent access day 1 locomotion0.10.10.40.60.50.10.0-0.00.30.2-0.30.3-0.4-0.3-0.3-0.30.40.40.4-0.3
Intermittent access day 15 total locomotion0.40.50.6-0.7-0.7-0.80.7-0.7-0.7-0.70.7-0.60.60.70.60.7-0.5-0.5-0.60.6
Intermittent access total locomotion0.80.91.3-0.7-0.8-1.10.9-0.9-0.9-1.11.0-1.00.91.11.01.1-0.9-0.9-0.90.9
Intermittent access standard deviation1.71.83.6-1.9-1.8-1.30.9-0.9-1.5-1.31.3-1.31.31.31.31.4-1.2-1.2-1.11.3
Left kidney weight0.61.79.60.10.51.8-3.13.11.11.2-1.20.8-0.6-0.6-0.3-0.00.10.1-0.0-0.6
Right kidney weight0.30.82.9-1.0-0.60.2-1.71.7-0.2-0.20.1-0.40.60.70.91.1-0.9-0.9-1.00.4
Cocaine induced anxiety0.00.00.1-0.3-0.30.3-0.20.2-0.10.10.0-0.10.2-0.10.1-0.1-0.1-0.1-0.00.2
Post-drug Anxiety0.40.51.10.60.50.50.2-0.20.50.6-0.50.6-0.7-0.8-0.8-1.10.90.90.9-0.7
Baseline Anxiety0.30.31.70.0-0.2-0.81.3-1.3-0.3-0.40.4-0.20.00.1-0.1-0.20.30.30.2-0.2
Tail length11.936.151.35.96.36.3-7.27.26.36.2-6.46.2-5.9-5.6-5.5-5.05.45.45.3-5.6
Length with tail9.233.759.65.05.76.7-7.77.76.16.2-6.25.8-5.4-5.4-5.0-4.64.84.84.7-5.6
Length without tail0.81.85.70.51.01.9-2.42.41.51.5-1.31.1-0.9-1.2-0.9-0.90.80.80.7-1.4
Times rat made contact with spout0.00.00.10.40.2-0.20.4-0.40.0-0.1-0.00.1-0.1-0.1-0.2-0.10.10.10.20.0
Lifetime Intake0.00.00.10.30.2-0.10.2-0.20.1-0.00.00.0-0.00.0-0.00.00.10.10.00.2
Liver weight, left0.81.41.91.01.11.2-0.80.81.41.2-1.31.2-1.2-1.2-1.2-1.21.11.11.3-1.2
Liver weight, right1.62.65.01.01.51.7-2.22.22.01.6-1.81.7-1.6-1.4-1.3-1.01.31.31.4-1.6
Locomotor activity0.91.52.8-0.9-1.1-1.41.7-1.7-1.3-1.31.3-1.21.11.11.00.9-0.9-0.9-1.01.3
Locomotor testing distance1.93.26.9-1.2-1.6-2.32.6-2.6-1.9-2.01.9-1.71.61.71.51.4-1.3-1.3-1.31.7
Locomotor testing rearing0.40.62.9-0.3-0.6-1.31.7-1.7-0.8-0.90.7-0.50.30.50.30.2-0.0-0.0-0.10.6
Locomotion in novel chamber0.50.61.01.00.90.4-0.40.41.00.6-0.90.9-1.0-0.7-0.9-0.70.90.90.9-0.5
Locomotion in novel chamber post-restriction2.02.43.5-1.1-1.4-1.81.9-1.9-1.7-1.71.7-1.61.61.51.51.4-1.5-1.5-1.31.3
Fecal boli incidents, locomotor time 12.42.74.4-2.1-1.9-1.41.3-1.3-1.8-1.51.6-1.71.71.61.61.5-1.8-1.8-1.71.3
Change in fecal boli incidents, locomotor task2.32.13.41.81.71.3-1.31.31.61.4-1.51.5-1.5-1.4-1.5-1.41.51.51.5-0.8
Time >=10cm from walls, locomotor time 10.10.10.30.60.3-0.10.5-0.50.10.0-0.10.2-0.3-0.2-0.3-0.30.30.30.20.5
Bouts of movement, locomotor time 10.00.10.3-0.2-0.00.1-0.30.30.0-0.10.0-0.10.10.20.20.2-0.4-0.4-0.50.0
Total resting periods, locomotor time 10.10.10.4-0.4-0.10.1-0.40.4-0.0-0.10.1-0.20.20.30.30.4-0.5-0.5-0.6-0.0
Rest time, locomotor task time 10.20.20.5-0.7-0.3-0.30.2-0.2-0.3-0.40.3-0.40.40.50.50.6-0.6-0.6-0.50.6
Distance moved, locomotor task time 10.91.01.71.31.00.8-1.01.01.00.9-1.01.0-1.1-0.9-1.0-0.91.01.01.0-0.4
Vertical activity count, locomotor time 10.20.21.01.00.60.4-0.40.40.30.4-0.40.4-0.4-0.4-0.4-0.40.30.30.5-0.4
Time >=10cm from walls, locomotor time 20.40.40.90.90.70.2-0.20.20.60.4-0.60.7-0.7-0.5-0.7-0.50.90.90.7-0.9
Bouts of movement, locomotor time 20.10.10.2-0.4-0.4-0.50.3-0.3-0.4-0.40.4-0.40.30.40.30.3-0.4-0.4-0.50.3
Total resting periods, locomotor time 20.20.20.2-0.4-0.4-0.50.4-0.4-0.4-0.40.4-0.40.40.40.40.3-0.4-0.4-0.50.4
Rest time, locomotor task time 20.91.02.11.11.11.10.1-0.10.91.1-0.91.0-1.1-1.3-1.3-1.51.01.01.0-0.2
Distance moved, locomotor task time 20.40.52.60.50.50.6-1.61.60.60.5-0.60.5-0.4-0.2-0.20.10.30.30.4-0.4
Vertical activity count, locomotor time 20.20.31.50.10.10.1-1.21.20.1-0.1-0.1-0.10.20.40.40.7-0.3-0.3-0.2-0.1
Light reinforcement 10.81.43.4-0.7-1.0-1.71.8-1.8-1.3-1.41.3-1.11.01.10.90.9-0.7-0.7-0.81.0
Light reinforcement 20.10.10.3-0.1-0.1-0.60.5-0.5-0.4-0.50.4-0.30.30.40.30.4-0.3-0.3-0.30.5
Bone: marrow area0.20.40.8-0.9-0.60.2-0.90.9-0.2-0.20.3-0.40.60.50.70.7-0.9-0.9-0.90.7
Bone: maximum diameter0.40.71.4-1.2-1.0-0.70.1-0.1-0.6-0.80.8-0.80.90.90.91.0-1.0-1.0-1.00.9
Bone: maximum force0.50.81.7-1.1-0.9-0.7-0.40.4-0.5-0.80.7-0.80.91.11.11.3-1.2-1.2-1.10.7
Bone: maximum moment0.50.91.9-1.1-0.9-0.6-0.60.6-0.5-0.80.7-0.80.91.11.21.4-1.2-1.2-1.20.7
Mean time between licks in bursts0.00.10.2-0.2-0.30.00.1-0.1-0.3-0.10.2-0.30.30.20.20.1-0.4-0.4-0.10.2
Mean num. licks in bursts0.00.10.20.20.10.2-0.40.40.10.2-0.20.2-0.2-0.2-0.2-0.20.20.20.2-0.2
Cd content in liver0.50.60.80.80.70.6-0.50.50.70.7-0.70.8-0.9-0.8-0.9-0.90.80.80.8-0.7
Co content in liver0.00.00.1-0.2-0.10.4-0.30.30.00.2-0.1-0.00.0-0.10.0-0.1-0.2-0.2-0.20.2
Cu content in liver1.72.13.21.41.51.6-0.50.51.61.6-1.41.4-1.5-1.7-1.6-1.81.51.51.4-1.4
Fe content in liver1.92.23.41.11.41.8-1.81.81.71.6-1.61.5-1.4-1.5-1.4-1.31.31.31.2-1.5
K content in liver0.10.10.3-0.6-0.5-0.30.0-0.0-0.3-0.30.3-0.30.30.40.40.5-0.3-0.3-0.40.4
Mg content in liver0.60.60.80.60.70.6-0.30.30.80.7-0.70.8-0.9-0.8-0.9-0.90.90.90.9-0.8
Mn content in liver1.82.03.21.71.51.0-0.00.01.21.3-1.21.4-1.5-1.6-1.7-1.81.71.71.7-1.3
Na content in liver1.11.21.9-1.1-1.2-1.11.4-1.4-1.2-1.11.1-1.11.01.00.90.8-0.8-0.8-0.81.1
Rb content in liver0.20.21.2-0.00.1-0.41.1-1.10.1-0.10.10.1-0.1-0.1-0.3-0.30.40.40.4-0.6
Se content in liver0.20.20.5-0.7-0.7-0.70.4-0.4-0.5-0.60.4-0.40.30.50.40.6-0.3-0.3-0.40.5
Sr content in liver2.01.92.51.61.41.4-1.61.61.21.4-1.41.4-1.3-1.3-1.3-1.21.31.31.3-1.1
Zn content in liver0.10.20.5-0.2-0.4-0.70.7-0.7-0.5-0.50.4-0.30.20.30.20.20.00.00.00.1
Bone: minimum diameter0.10.21.6-0.4-0.20.4-1.31.30.10.1-0.20.00.10.10.30.4-0.4-0.4-0.30.1
Time in familiar zone, hab. session 10.40.30.60.80.60.10.7-0.70.40.3-0.30.5-0.6-0.6-0.7-0.80.60.60.7-0.4
Time in novel zone, hab. session 12.92.83.6-1.8-1.8-1.71.0-1.0-1.8-1.81.7-1.71.71.81.81.9-1.7-1.7-1.71.6
Total zone transitions, hab. session 16.69.310.53.03.13.2-2.32.33.13.2-3.13.1-3.0-3.2-3.1-3.23.13.13.1-3.2
Total locomotion distance, hab. session 12.43.44.31.91.91.7-1.21.21.91.8-1.81.9-1.9-1.9-2.0-2.02.02.02.0-2.1
Locomotion velocity, hab. session 13.65.16.12.22.32.3-1.81.82.42.3-2.32.3-2.3-2.3-2.3-2.32.32.32.3-2.5
Time in familiar zone, hab. session 20.60.61.7-0.6-0.7-1.01.3-1.3-0.8-0.80.8-0.70.60.60.50.5-0.4-0.4-0.50.6
Time in novel zone, hab. session 20.10.10.50.20.30.3-0.70.70.40.3-0.30.3-0.3-0.1-0.10.00.10.10.1-0.2
Total zone transitions, hab. session 21.62.12.71.51.51.5-0.80.81.41.5-1.41.4-1.4-1.6-1.5-1.61.51.51.5-1.5
Total locomotion distance, hab. session 20.00.00.10.00.10.1-0.00.00.10.1-0.10.1-0.1-0.1-0.1-0.10.10.10.2-0.3
Locomotion velocity, hab. session 20.10.10.20.10.20.3-0.40.40.30.3-0.30.2-0.2-0.2-0.2-0.20.20.20.2-0.4
Novel to familiar place preference ratio1.31.43.11.01.11.5-1.81.81.31.3-1.31.1-1.1-1.1-1.0-0.90.70.70.7-0.8
Novelty place preference1.41.53.21.11.21.5-1.81.81.41.3-1.31.2-1.2-1.1-1.0-0.90.70.70.7-0.9
Time in novel zone, NPP test1.01.12.11.01.11.2-1.51.51.21.1-1.11.1-1.0-1.0-0.9-0.80.60.60.7-0.7
Total zone transitions, NPP test3.44.96.82.22.22.1-1.51.52.12.2-2.22.2-2.2-2.3-2.3-2.32.52.52.5-2.6
Total locomotion distance, NPP test0.81.12.20.91.00.8-0.50.51.01.0-1.01.0-1.0-1.1-1.1-1.11.31.31.3-1.5
Locomotion velocity, NPP test1.52.13.41.21.31.4-1.21.21.41.5-1.41.4-1.4-1.4-1.4-1.41.61.61.6-1.8
Intraocular pressure1.31.82.81.41.61.7-1.51.51.61.5-1.51.4-1.3-1.4-1.3-1.20.90.91.0-1.0
Delta distance traveled before/after self-admin2.32.53.5-1.3-1.4-1.31.0-1.0-1.5-1.51.7-1.81.81.61.81.7-1.9-1.9-1.91.5
Delta ambulatory time before/after self-admin2.52.73.7-1.5-1.5-1.40.9-0.9-1.7-1.71.7-1.81.91.81.91.9-1.9-1.9-1.91.4
Parametrial fat weight0.10.20.4-0.2-0.2-0.60.2-0.2-0.1-0.50.3-0.30.30.50.40.6-0.4-0.4-0.50.5
Pavlov. Cond. lever latency1.01.33.0-1.3-1.1-0.4-0.10.1-0.9-0.80.9-1.11.21.11.31.2-1.6-1.6-1.71.3
Pavlov. Cond. magazine entry latency0.20.31.50.1-0.1-1.20.9-0.9-0.3-0.80.4-0.20.10.50.20.4-0.0-0.0-0.00.3
Pavlov. Cond. change in total contacts1.21.32.41.61.30.30.3-0.31.10.8-1.01.2-1.3-1.1-1.3-1.21.51.51.4-1.1
Pavlov. Cond. index score0.30.40.90.80.5-0.60.8-0.80.2-0.1-0.20.4-0.6-0.3-0.6-0.40.80.80.9-0.5
Pavlov. Cond. latency score0.30.41.10.90.6-0.30.6-0.60.30.1-0.40.6-0.7-0.4-0.7-0.60.90.91.1-0.7
Pavlov. Cond. lever contacts1.31.63.01.51.30.50.1-0.11.00.9-1.01.2-1.3-1.2-1.4-1.41.61.61.7-1.4
Pavlov. Cond. magazine entry number0.30.41.8-0.5-0.11.1-1.31.30.10.6-0.30.00.2-0.20.20.1-0.4-0.4-0.50.0
Pavlov. Cond. intertrial magazine entries0.70.81.40.70.91.2-0.80.81.11.1-1.00.9-0.9-1.0-0.9-0.90.70.70.6-0.9
Pavlov. Cond. lever-magazine prob. diff.0.30.30.80.80.5-0.70.8-0.80.2-0.2-0.10.4-0.5-0.2-0.5-0.30.80.80.9-0.4
Pavlov. Cond. response bias0.30.40.90.80.5-0.71.0-1.00.2-0.1-0.10.4-0.5-0.2-0.5-0.40.80.80.9-0.5
Pavlov. Cond. lever latency0.60.81.00.90.91.0-1.01.01.01.0-0.90.9-0.9-0.9-0.9-0.90.80.80.6-0.7
Pavlov. Cond. magazine entry latency0.60.71.20.90.90.8-1.11.10.70.8-0.90.8-0.8-0.7-0.7-0.60.70.70.9-0.8
Pavlov. Cond. change in total contacts0.30.40.6-0.4-0.5-0.80.7-0.7-0.7-0.70.6-0.60.60.70.60.6-0.5-0.5-0.30.4
Pavlov. Cond. index score0.20.30.5-0.4-0.5-0.60.2-0.2-0.6-0.60.5-0.50.60.60.60.7-0.6-0.6-0.30.4
Pavlov. Cond. latency score0.10.10.3-0.2-0.2-0.3-0.20.2-0.3-0.30.2-0.30.30.40.40.5-0.3-0.3-0.10.2
Pavlov. Cond. lever contacts0.60.81.2-0.8-0.9-1.11.0-1.0-1.0-1.00.9-0.90.80.90.90.9-0.7-0.7-0.50.7
Pavlov. Cond. magazine entry number0.00.00.2-0.2-0.20.00.4-0.40.00.00.1-0.0-0.0-0.1-0.1-0.30.10.1-0.10.1
Pavlov. Cond. intertrial magazine entries1.82.33.51.31.51.7-0.80.81.71.7-1.51.5-1.5-1.8-1.7-1.91.51.51.5-1.7
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.5-0.5-0.60.2-0.2-0.7-0.60.5-0.60.60.70.70.8-0.6-0.6-0.30.4
Pavlov. Cond. response bias0.50.71.1-0.7-0.8-1.00.8-0.8-0.9-1.00.8-0.80.80.90.91.0-0.7-0.7-0.50.6
Time in closed arm before self-admin0.91.01.9-1.4-1.3-1.30.9-0.9-1.3-1.11.0-1.01.01.01.01.0-0.7-0.7-0.60.3
Time in closed arm after self-admin0.30.30.8-0.9-0.7-0.30.1-0.1-0.6-0.40.5-0.60.60.50.60.5-0.5-0.5-0.60.5
Time in open arm before self-admin0.20.20.90.90.80.7-0.10.10.60.5-0.30.2-0.2-0.4-0.3-0.40.20.2-0.10.0
Time in open arm after self-admin0.30.41.11.00.80.50.5-0.50.50.5-0.40.5-0.5-0.7-0.7-0.90.60.60.6-0.6
Bone: periosteal estimation0.30.61.2-1.1-0.9-0.4-0.50.5-0.4-0.60.5-0.70.80.80.91.0-1.0-1.0-1.00.8
Bone: periosteal perimeter0.20.41.1-1.0-0.8-0.1-0.50.5-0.4-0.40.4-0.50.60.60.70.7-0.8-0.8-0.80.7
Bone: post-yield work0.10.20.6-0.4-0.20.1-0.50.50.0-0.10.2-0.30.30.30.40.5-0.7-0.7-0.70.4
Progressive ratio test 1 active lever presses0.10.10.80.90.7-0.1-0.40.40.30.0-0.20.2-0.20.0-0.00.20.10.1-0.00.0
Progressive ratio test 1 breakpoint0.20.21.21.10.90.2-0.60.60.50.3-0.40.5-0.4-0.2-0.3-0.10.40.40.3-0.3
Progressive ratio test 1 inactive lever presses0.10.10.40.0-0.1-0.60.6-0.6-0.2-0.50.3-0.30.20.40.30.4-0.2-0.2-0.20.2
Progressive ratio test 2 active lever presses0.10.10.20.50.4-0.30.4-0.40.0-0.10.00.0-0.10.0-0.1-0.00.20.20.1-0.0
Progressive ratio test 2 breakpoint0.00.00.20.40.3-0.40.4-0.4-0.0-0.20.1-0.10.00.10.00.10.10.1-0.00.1
Progressive ratio test 2 inactive lever presses0.10.10.30.10.10.10.5-0.50.20.2-0.10.2-0.3-0.4-0.4-0.50.50.50.5-0.2
Incentive Sensitization - Responses0.10.10.3-0.3-0.3-0.50.6-0.6-0.3-0.40.3-0.30.20.30.20.2-0.1-0.1-0.10.2
Incentive Sensitization - Breakpoint0.20.20.5-0.6-0.5-0.70.6-0.6-0.5-0.60.5-0.40.40.50.40.5-0.3-0.3-0.30.4
Sum of active levers in priming session hrs 5-63.02.94.41.91.81.5-1.11.11.61.6-1.71.8-1.9-1.8-1.8-1.82.12.11.8-1.2
Progressive ratio0.40.41.0-0.2-0.00.5-0.40.40.30.6-0.60.6-0.7-0.7-0.7-0.71.01.00.9-0.8
Food seeking constrained by brief footshock0.70.91.3-1.1-1.0-1.00.5-0.5-0.8-1.00.9-0.90.91.01.01.0-1.1-1.1-1.10.8
Seeking ratio, punishment vs. effort0.60.71.70.1-0.0-0.70.3-0.3-0.3-0.80.7-0.70.70.90.81.0-1.3-1.3-1.21.1
Retroperitoneal fat weight0.30.92.2-1.4-0.9-0.4-1.11.1-0.3-0.70.5-0.70.91.11.21.5-1.1-1.1-1.10.5
Reaction time number correct0.20.30.80.10.20.7-0.40.40.40.6-0.50.5-0.5-0.6-0.6-0.70.60.60.9-0.8
Reaction time mean minus median0.20.31.51.20.90.20.6-0.60.60.3-0.20.3-0.4-0.5-0.5-0.70.50.50.3-0.5
Reaction time mean minus median AUC0.40.51.81.41.00.01.0-1.00.50.3-0.20.4-0.5-0.5-0.7-0.80.60.60.5-0.6
Reaction time num false alarms0.10.20.50.60.40.1-0.20.20.10.2-0.30.4-0.4-0.4-0.4-0.40.60.60.7-0.6
Reaction time num false alarms AUC0.20.30.70.70.50.2-0.40.40.30.4-0.50.5-0.6-0.5-0.6-0.50.70.70.9-0.6
Reaction time trials correct on left0.20.30.80.10.20.7-0.40.40.40.6-0.50.5-0.5-0.6-0.6-0.70.60.60.9-0.8
Reaction time trials on left0.20.30.80.10.20.7-0.40.40.40.6-0.50.5-0.5-0.6-0.6-0.70.60.60.9-0.8
Reaction time mean0.30.41.70.50.1-0.61.3-1.3-0.3-0.50.6-0.50.40.30.30.1-0.5-0.5-0.70.5
Reaction time mean AUC0.30.41.60.60.3-0.51.3-1.3-0.2-0.40.6-0.40.40.30.20.1-0.5-0.5-0.70.5
Median of all reaction times0.60.82.4-0.0-0.4-1.01.6-1.6-0.8-0.91.0-0.90.80.70.60.5-0.8-0.8-1.01.0
Reaction time omissions0.10.10.30.60.4-0.40.4-0.40.1-0.30.2-0.20.10.30.20.3-0.3-0.3-0.30.1
Reaction time false alarm rate0.00.00.20.50.2-0.3-0.10.1-0.1-0.1-0.00.1-0.10.0-0.00.00.20.20.1-0.0
Reaction time premature initiation rate0.30.30.91.00.90.4-0.40.40.70.5-0.60.6-0.6-0.4-0.5-0.40.60.60.5-0.5
Reaction time premature initiations0.60.91.21.11.10.9-0.70.70.90.9-1.01.0-0.9-0.9-0.9-0.81.01.01.1-1.1
Std. dev. reaction times0.10.21.11.10.70.00.5-0.50.40.1-0.10.2-0.2-0.2-0.3-0.30.20.20.0-0.3
Reaction time trials completed0.20.30.80.10.20.7-0.40.40.40.6-0.50.5-0.5-0.6-0.6-0.70.60.60.9-0.8
Reaction time trials AUC0.20.30.90.10.30.6-0.30.30.40.6-0.50.5-0.5-0.7-0.6-0.70.60.60.9-0.9
Run reversals in cocaine runway, females0.50.52.00.60.70.9-1.41.40.60.7-0.60.5-0.4-0.4-0.3-0.20.20.20.20.0
Run reversals in cocaine runway, males1.61.55.3-0.8-1.0-1.42.3-2.3-1.3-1.21.3-1.21.10.90.80.5-0.7-0.7-0.60.8
Latency to leave start box in cocaine runway1.71.93.9-2.0-1.8-0.90.7-0.7-1.4-1.21.4-1.51.61.31.51.3-1.4-1.4-1.61.0
Latency to leave start box in cocaine runway, F2.93.25.6-2.4-2.1-1.30.9-0.9-1.8-1.61.8-1.92.01.82.01.9-2.0-2.0-1.91.4
Latency to leave start box in cocaine runway, M0.50.41.1-1.0-0.9-0.40.5-0.5-0.6-0.60.7-0.70.60.60.60.6-0.7-0.7-1.00.3
Std. dev. time between licks in bursts1.11.31.6-1.2-1.3-1.01.0-1.0-1.2-1.11.2-1.21.21.11.21.0-1.2-1.2-1.11.2
Total sessions with >9 infusions0.50.51.0-0.4-0.4-0.90.5-0.5-0.5-0.80.7-0.70.70.90.81.0-0.8-0.8-0.80.7
Short access day 1 total inactive lever presses2.63.04.91.61.61.1-0.10.11.71.5-1.61.8-2.0-1.8-2.0-2.12.22.22.2-1.8
Short access day 10 total inactive lever presses0.80.91.80.40.60.80.1-0.10.90.9-0.80.9-1.0-1.1-1.2-1.41.11.11.1-1.2
Short access day 1 total infusions0.00.00.30.10.1-0.10.5-0.50.2-0.00.00.0-0.0-0.1-0.1-0.10.20.20.10.1
Short access day 10 total infusions0.30.40.8-0.4-0.6-0.60.4-0.4-0.5-0.60.6-0.60.60.60.60.7-0.6-0.6-0.60.9
Short access total infusions0.00.00.10.1-0.0-0.10.1-0.1-0.0-0.10.1-0.10.10.10.10.2-0.0-0.0-0.10.3
Short access day 1 locomotion0.91.01.5-1.1-1.0-1.21.1-1.1-0.8-1.10.9-0.90.91.11.01.1-0.8-0.8-0.70.9
Short access day 10 total locomotion0.50.61.1-1.0-1.0-1.00.4-0.4-1.0-0.90.7-0.70.70.90.80.9-0.5-0.5-0.50.4
Short access total locomotion0.80.81.4-1.2-1.1-1.00.5-0.5-1.0-1.00.9-0.90.91.01.01.1-0.7-0.7-0.70.6
One hour access (0.3 mA shock)0.40.51.01.00.90.5-0.20.20.60.6-0.70.7-0.8-0.7-0.8-0.80.80.80.8-0.5
Compulsive drug intake6.76.89.93.13.12.4-1.81.82.72.6-2.72.7-2.7-2.6-2.7-2.72.62.62.5-2.3
One hour access (shock baseline)2.52.93.6-1.9-1.9-1.81.4-1.4-1.9-1.81.8-1.81.71.71.71.7-1.6-1.6-1.61.6
Social response proportion0.91.03.10.91.00.9-1.81.81.00.9-1.11.0-1.0-0.7-0.7-0.50.70.70.8-0.8
Social responses0.00.10.40.20.20.0-0.60.6-0.00.1-0.10.1-0.2-0.0-0.00.1-0.1-0.1-0.00.0
Social time0.10.10.50.30.0-0.30.7-0.7-0.4-0.20.3-0.20.10.0-0.0-0.20.00.0-0.20.4
Soleus weight0.92.64.1-1.8-1.7-1.70.6-0.6-1.6-1.81.6-1.61.71.91.82.0-1.6-1.6-1.61.3
Bone: stiffness0.10.10.4-0.4-0.2-0.1-0.60.60.1-0.20.1-0.20.20.30.40.5-0.4-0.4-0.50.1
Tibialis anterior weight0.41.42.51.01.21.6-1.31.31.21.3-1.21.0-0.9-1.2-1.0-1.10.80.81.2-1.4
Time to tail flick, vehicle, before self-admin1.51.52.31.41.31.1-0.50.51.31.2-1.21.3-1.4-1.4-1.4-1.51.31.31.2-0.7
Time to tail flick, vehicle, after self-admin0.10.20.5-0.4-0.4-0.40.7-0.7-0.3-0.40.4-0.40.30.30.30.2-0.3-0.3-0.20.4
Time to tail flick, test, before self-admin0.00.00.1-0.3-0.30.10.1-0.1-0.30.00.1-0.10.1-0.00.0-0.1-0.2-0.2-0.00.3
Time to tail flick, test, after self-admin0.10.10.7-0.00.0-0.1-0.30.3-0.0-0.20.2-0.20.30.40.40.5-0.5-0.5-0.60.8
Delta time to tail flick, vehicle, before/after SA1.31.31.7-1.3-1.2-1.21.1-1.1-1.2-1.21.1-1.21.21.21.21.2-1.1-1.1-0.90.8
Delta time to tail flick, test, before/after SA0.20.20.50.50.60.2-0.70.70.60.2-0.40.4-0.3-0.1-0.20.10.20.20.20.1
Tibia length0.20.61.2-0.8-0.6-0.0-0.90.9-0.3-0.40.4-0.70.80.81.01.1-1.1-1.1-0.90.5
Ambulatory time before self-admin0.30.40.80.50.50.6-0.50.50.50.6-0.60.6-0.5-0.6-0.6-0.50.60.60.9-0.8
Ambulatory time after self-admin1.21.42.3-1.1-1.0-0.6-0.20.2-1.1-0.91.1-1.31.41.31.51.5-1.5-1.5-1.41.1
Bone: tissue strength0.10.10.2-0.2-0.2-0.10.2-0.2-0.2-0.20.3-0.30.30.30.30.2-0.5-0.5-0.50.4
Total heroin consumption1.31.62.41.61.41.0-0.10.11.31.2-1.11.3-1.4-1.4-1.5-1.51.41.41.3-1.4
Bone: trabecular number1.01.63.1-1.2-1.2-1.81.7-1.7-1.0-1.51.3-1.11.01.31.11.2-1.0-1.0-1.01.2
Bone: trabecular spacing0.00.10.10.20.10.20.2-0.2-0.20.2-0.00.1-0.1-0.3-0.2-0.40.30.30.3-0.4
Bone: trabecular thickness1.21.52.5-1.4-1.2-0.9-0.00.0-0.9-1.11.0-1.21.21.41.41.6-1.5-1.5-1.51.4
Bone: trabecular tissue density0.10.20.40.40.30.3-0.20.20.30.3-0.40.4-0.4-0.4-0.4-0.40.50.50.6-0.6
Water consumed over 24 hours0.20.20.40.70.50.30.2-0.20.40.4-0.30.4-0.4-0.5-0.5-0.60.50.50.6-0.4
Number of responses in last shaping day0.10.10.6-0.0-0.1-0.10.8-0.8-0.2-0.10.3-0.20.20.10.1-0.0-0.2-0.2-0.20.2