Hub : Genes

Sp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative TSS NM_001399622.1 0.02 0.02 2.4e-03 0.03 0.01 0.01 0.02 8.5e-04 1.2e-02 1.8e-02 3.2e-03
2 PL alternative TSS XM_039086079.1 0.03 0.02 2.3e-03 0.03 0.02 0.02 0.02 6.7e-04 4.9e-03 4.2e-03 2.2e-03
3 Adipose alternative TSS XM_063269117.1 0.03 0.03 7.3e-03 0.01 0.01 0.01 0.01 1.3e-02 1.9e-02 3.1e-02 3.2e-02
4 Adipose gene expression Sp2 0.02 0.01 4.9e-03 0.02 0.02 0.01 0.01 3.5e-03 4.6e-03 5.0e-02 1.0e-02
5 pVTA alternative TSS XM_039086080.1 0.04 0.03 5.2e-04 0.04 0.03 0.03 0.04 3.0e-04 8.5e-04 1.4e-03 5.2e-04
6 Liver mRNA stability Sp2 0.06 0.04 9.1e-10 0.07 0.08 0.07 0.09 1.8e-08 3.4e-09 9.6e-09 8.9e-10
7 Adipose alternative TSS XM_063269117.1 0.04 0.06 5.7e-03 0.01 0.01 0.01 0.01 9.5e-03 3.1e-02 1.7e-02 2.5e-02
8 pVTA gene expression Sp2 0.06 0.04 1.9e-04 0.03 0.03 0.01 0.03 1.9e-03 1.4e-03 2.7e-02 2.7e-03
9 Liver gene expression Sp2 0.05 0.03 2.4e-08 0.06 0.07 0.07 0.07 8.8e-07 3.5e-08 2.6e-08 2.7e-08
10 BLA gene expression Sp2 0.07 0.06 2.4e-03 0.04 0.04 0.02 0.03 2.9e-03 2.6e-03 4.1e-02 7.3e-03
11 NAcc alternative TSS NM_001399622.1 0.02 0.01 1.8e-03 0.02 0.01 0.01 0.01 7.3e-04 2.5e-03 5.1e-03 3.7e-03
12 IC alternative TSS XM_039086079.1 0.06 0.05 6.6e-03 0.06 0.03 0 0.04 2.5e-03 1.6e-02 2.0e-01 7.0e-03
13 NAcc alternative TSS XM_039086079.1 0.02 0.02 7.4e-04 0.01 0.02 0.02 0.02 4.3e-03 6.5e-04 4.3e-04 1.6e-03
14 IL gene expression Sp2 0.37 0.22 3.4e-04 0.05 0.1 0.05 0.08 3.0e-02 1.9e-03 2.3e-02 5.6e-03
15 NAcc alternative TSS XM_063269117.1 0.03 0.02 4.8e-05 0.03 0.03 0.03 0.03 5.0e-05 2.2e-05 4.6e-05 1.9e-05
16 Brain alternative TSS XM_039086080.1 0.02 0.02 7.5e-03 0.01 0.02 0.01 0.01 4.8e-02 9.1e-03 3.7e-02 4.4e-02
17 Brain gene expression Sp2 0.07 0.06 5.3e-06 0.06 0.06 0.06 0.07 1.6e-06 2.4e-06 1.8e-06 6.7e-07
18 PL gene expression Sp2 0.08 0.05 3.6e-10 0.09 0.09 0.08 0.08 1.0e-09 3.0e-10 3.1e-09 2.8e-09
19 Brain alternative TSS XM_039086079.1 0.02 0.02 3.2e-03 0.03 0.03 0.03 0.03 1.1e-03 1.1e-03 1.5e-03 1.6e-03
20 Adipose alternative TSS XM_039086078.2 0.08 0.09 4.4e-03 0.01 0.01 0.02 0.01 3.5e-02 2.1e-02 2.5e-03 1.2e-02
21 IC gene expression Sp2 0.1 0.07 1.9e-04 0.02 0.04 0.04 0.01 4.2e-02 1.1e-02 6.9e-03 1.5e-01
22 NAcc gene expression Sp2 0.03 0.02 9.5e-06 0.04 0.04 0.04 0.04 2.3e-06 2.9e-06 2.4e-07 1.8e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.93.35.8-2.1-2.12.01.91.92.01.81.41.71.5-1.6-1.6-2.11.91.61.81.82.0-1.82.4-0.01.3
Area under the delay curve0.70.86.10.80.8-0.6-0.5-0.5-0.7-0.8-0.8-0.8-0.90.70.60.1-0.4-1.0-0.8-0.8-0.50.51.02.5-1.3
BMI with tail12.543.154.2-7.3-7.37.37.37.37.37.37.47.27.3-6.9-7.0-5.16.95.76.56.96.5-6.63.8-4.12.9
BMI without tail0.62.04.5-1.7-1.71.71.71.71.61.82.11.81.8-1.4-1.5-0.41.60.41.01.41.1-1.20.30.0-0.0
Body weight1.04.416.7-2.2-2.22.22.32.32.22.34.12.33.1-2.1-2.20.62.8-0.90.82.21.4-2.00.10.60.5
Weight adjusted by age0.50.81.31.21.2-1.1-1.1-1.1-1.1-0.8-0.7-0.8-0.80.80.80.8-0.9-0.9-0.9-0.9-1.01.1-0.80.3-0.3
Bone surface0.50.91.5-1.2-1.21.21.11.11.21.01.10.81.0-0.8-0.8-0.61.10.60.91.10.9-1.00.4-0.60.7
Bone volume1.62.94.0-2.0-2.02.01.91.92.01.71.81.71.7-1.6-1.6-1.41.91.21.61.81.8-1.81.4-0.81.3
Breakpoint value in progressive ratio session3.03.67.51.61.6-1.6-1.6-1.6-1.7-1.6-1.5-1.8-1.72.12.12.4-2.0-2.1-2.1-1.8-2.12.1-2.00.7-2.7
Number of licking bursts0.10.10.30.20.2-0.2-0.2-0.2-0.2-0.3-0.6-0.3-0.40.30.3-0.2-0.40.1-0.1-0.6-0.20.40.10.10.0
Context. condit. distance diff. score0.30.32.5-0.5-0.50.50.50.50.50.40.60.40.6-0.5-0.5-0.10.50.40.50.60.4-0.5-0.3-1.60.6
Locomotion velocity, session 10.40.52.0-0.5-0.50.50.50.50.50.61.00.71.0-0.7-0.60.00.80.40.60.80.6-0.6-0.3-0.71.4
Locomotion distance, session 12.43.05.81.81.8-1.8-1.8-1.8-1.8-1.8-1.0-1.7-1.31.61.72.4-1.5-2.4-2.1-1.8-1.91.5-1.91.0-1.1
Locomotion velocity, session 20.91.02.21.11.1-1.1-1.1-1.1-1.1-1.0-0.6-1.0-0.81.01.11.4-0.8-1.5-1.2-0.9-1.00.9-0.81.0-0.0
Locomotion distance, session 23.14.37.42.22.2-2.2-2.2-2.2-2.2-2.1-1.5-2.0-1.92.02.12.3-1.8-2.7-2.4-2.1-2.22.0-1.32.1-1.1
Locomotion velocity, session 30.00.00.3-0.0-0.00.00.00.00.0-0.00.1-0.0-0.00.0-0.00.20.0-0.5-0.3-0.2-0.20.10.10.0-0.6
Locomotion distance, session 32.83.05.31.91.9-1.9-1.9-1.9-1.9-1.9-1.3-1.8-1.61.71.81.9-1.5-2.3-2.0-1.7-1.81.7-1.31.2-0.4
Stereotopy head waving bouts, day 34.55.27.7-2.4-2.42.42.42.42.42.41.82.41.9-2.3-2.3-2.82.32.32.42.42.5-2.22.7-0.51.5
Stereotopy head waving duration, day 33.44.04.9-2.2-2.22.22.22.22.22.21.82.21.9-2.1-2.1-2.12.01.92.12.12.1-2.01.8-0.71.1
Locomotion velocity, session 71.51.72.51.31.3-1.3-1.2-1.2-1.3-1.2-1.1-1.3-1.21.31.31.4-1.3-1.3-1.4-1.4-1.41.4-1.6-0.4-1.4
Locomotion distance, session 74.76.07.22.62.6-2.6-2.6-2.6-2.6-2.5-2.4-2.6-2.62.62.62.2-2.5-2.6-2.7-2.5-2.52.6-1.71.2-1.6
Stereotopy head waving bouts, day 70.40.40.9-0.6-0.60.60.60.60.60.70.40.70.5-0.6-0.7-0.80.61.00.80.80.8-0.70.6-0.40.5
Stereotopy head waving duration, day 70.30.30.7-0.5-0.50.50.50.50.50.50.50.60.6-0.6-0.6-0.50.50.80.70.70.6-0.70.2-0.60.4
Locomotion velocity, session 80.20.31.6-0.0-0.0-0.0-0.0-0.00.10.10.90.00.7-0.2-0.01.20.2-0.4-0.10.2-0.2-0.3-1.3-1.00.1
Locomotion distance, session 80.81.12.71.11.1-1.1-1.1-1.1-1.1-1.1-0.4-1.0-0.70.91.01.6-0.8-1.6-1.3-1.0-1.10.8-1.4-0.1-0.5
Degree of sensitization distance0.10.11.20.00.0-0.00.00.0-0.10.1-0.2-0.1-0.20.20.20.3-0.3-0.0-0.2-0.3-0.30.3-0.4-0.0-1.1
Degree of sensitization stereotypy0.10.10.30.30.3-0.2-0.3-0.3-0.2-0.2-0.5-0.1-0.40.20.2-0.2-0.30.40.1-0.1-0.10.20.0-0.1-0.0
Conditioned locomotion1.01.12.0-1.1-1.11.11.11.11.11.21.01.11.0-1.1-1.1-1.11.20.71.01.01.2-1.21.4-0.10.7
Cocaine response after cond. corrected5.06.08.0-2.4-2.42.52.42.42.42.42.32.52.3-2.5-2.5-2.82.82.02.42.72.8-2.62.8-0.92.2
Cocaine response after cond. not corrected2.83.37.6-1.8-1.81.81.81.81.81.61.61.71.5-1.8-1.8-2.22.21.21.72.12.1-1.92.8-0.02.0
Cocaine response before conditioning2.32.73.91.71.7-1.7-1.7-1.7-1.7-1.8-1.9-1.9-2.01.81.81.3-1.6-1.8-1.8-1.7-1.61.7-0.51.6-0.6
Saline control response0.50.71.30.60.6-0.6-0.6-0.6-0.7-0.9-1.0-1.0-1.01.11.10.7-0.9-0.9-1.0-1.1-0.90.9-0.4-0.1-1.0
Bone: connectivity density0.30.41.8-0.7-0.70.70.60.60.70.50.00.40.2-0.3-0.3-1.10.50.70.70.70.8-0.51.30.30.5
Bone: cortical apparent density6.48.814.23.43.4-3.4-3.4-3.4-3.4-3.3-3.8-3.2-3.53.23.21.9-3.3-1.8-2.6-2.8-2.83.1-2.00.7-1.4
Bone: cortical area0.20.21.6-0.4-0.40.40.40.40.40.40.30.20.2-0.1-0.1-0.20.5-0.20.10.30.4-0.41.31.10.7
Bone: cortical porosity0.50.52.2-0.5-0.50.50.50.50.50.70.30.60.4-0.7-0.8-1.20.60.90.80.50.8-0.71.5-0.50.4
Bone: cortical porosity0.60.73.3-0.6-0.60.60.70.70.70.80.40.70.5-0.8-0.9-1.30.80.80.80.70.9-0.81.8-0.10.5
Bone: cortical thickness0.50.83.00.70.7-0.8-0.7-0.7-0.7-0.8-1.0-0.9-1.11.01.00.4-0.6-1.1-0.9-0.9-0.60.71.01.70.0
Bone: cortical thickness0.91.13.50.90.9-0.9-0.9-0.9-0.9-1.0-1.3-1.1-1.41.11.1-0.1-0.7-1.2-1.0-0.9-0.60.81.61.9-0.1
Bone: cortical tissue density6.99.414.93.53.5-3.5-3.5-3.5-3.5-3.4-3.9-3.3-3.63.43.42.0-3.4-1.9-2.7-2.9-2.93.2-2.10.8-1.4
Condit. Reinf. active minus inactive responses0.10.20.50.30.3-0.3-0.4-0.4-0.3-0.5-0.7-0.5-0.50.60.50.2-0.5-0.0-0.2-0.2-0.30.4-0.40.30.2
Condit. Reinf. active-inactive response ratio0.30.30.7-0.6-0.60.60.60.60.60.40.10.50.3-0.4-0.5-0.80.30.80.60.50.6-0.30.50.00.5
Condit. Reinf. active responses0.10.10.40.20.2-0.2-0.3-0.3-0.3-0.4-0.7-0.5-0.50.40.4-0.0-0.50.2-0.0-0.1-0.20.2-0.30.00.3
Condit. Reinf. inactive responses0.30.30.70.80.8-0.8-0.8-0.8-0.7-0.8-0.8-0.7-0.60.60.70.2-0.6-0.1-0.3-0.3-0.40.3-0.20.10.2
Incentive salience index mean0.30.31.10.50.5-0.5-0.5-0.5-0.5-0.7-1.1-0.7-0.90.70.60.0-0.8-0.1-0.4-0.6-0.50.6-0.20.3-0.0
Condit. Reinf. lever presses0.70.92.41.01.0-1.0-0.9-0.9-1.0-1.0-1.5-1.0-1.31.00.90.2-1.3-0.2-0.7-1.2-0.91.1-0.5-0.2-0.8
Condit. Reinf. active minus inactive responses0.10.10.9-0.2-0.20.30.20.20.20.30.10.40.1-0.4-0.4-0.90.40.20.20.20.4-0.20.90.00.3
Condit. Reinf. active-inactive response ratio0.40.52.3-0.7-0.70.70.70.70.60.70.40.70.5-0.8-0.8-1.00.60.90.70.50.7-0.50.3-1.5-0.1
Condit. Reinf. active responses0.10.10.70.20.2-0.2-0.2-0.2-0.2-0.1-0.3-0.0-0.3-0.0-0.0-0.70.0-0.0-0.0-0.10.10.10.80.30.5
Condit. Reinf. inactive responses0.50.61.50.80.8-0.8-0.8-0.8-0.8-0.8-1.1-0.8-1.00.70.7-0.2-0.7-0.5-0.6-0.7-0.50.70.61.20.6
Condit. Reinf. lever presses0.70.91.61.31.3-1.3-1.2-1.2-1.2-1.1-1.0-0.9-1.00.80.80.5-0.9-0.7-0.9-1.1-0.91.0-0.50.2-0.0
Condit. Reinf. lever reinforcers received0.10.20.40.50.5-0.5-0.5-0.5-0.5-0.4-0.6-0.4-0.60.30.3-0.4-0.3-0.3-0.3-0.4-0.20.50.70.60.2
Conditioned reinforcement - actives0.50.92.9-0.5-0.50.50.70.70.61.10.61.10.7-1.0-1.0-1.41.00.80.90.81.1-0.81.7-0.61.2
Conditioned reinforcement - inactives0.10.20.8-0.1-0.10.10.20.20.00.1-0.6-0.0-0.60.50.40.2-0.6-0.2-0.4-0.7-0.40.6-0.1-0.9-0.8
Conditioned locomotion4.05.29.7-1.7-1.71.71.91.91.82.51.92.62.1-2.6-2.4-3.02.42.22.42.12.5-2.33.1-2.02.6
Patch foraging indifference point 0 sec0.91.75.7-1.4-1.41.31.21.21.31.30.91.31.0-1.2-1.3-1.81.41.01.21.21.5-1.22.40.40.8
Patch foraging indifference point AUC0.30.41.60.60.6-0.6-0.6-0.6-0.6-0.7-0.5-0.5-0.40.40.40.7-0.7-0.1-0.4-0.6-0.60.5-1.3-1.0-0.6
Delay disc. indifference point, 0s delay1.92.17.01.11.1-1.1-1.1-1.1-1.1-1.4-1.7-1.4-1.61.51.40.5-1.4-1.1-1.3-1.6-1.21.40.52.6-2.6
Delay disc. indifference point, 16s delay0.50.61.8-0.5-0.50.60.80.80.50.60.70.60.6-0.6-0.6-0.80.90.10.50.70.8-1.01.31.21.1
Delay disc. indifference point, 2s delay0.70.76.20.30.3-0.4-0.3-0.3-0.4-0.5-0.8-0.5-0.90.40.2-0.6-0.4-0.6-0.7-0.9-0.30.61.82.5-1.1
Delay disc. indifference point, 24s delay0.40.42.90.60.6-0.6-0.5-0.5-0.6-0.6-0.2-0.6-0.40.60.60.8-0.3-0.9-0.6-0.3-0.40.2-0.21.70.0
Delay disc. indifference point, 4s delay4.44.611.32.02.0-1.9-1.8-1.8-2.0-2.1-1.9-2.1-2.32.22.11.4-1.8-2.6-2.4-2.3-2.02.00.13.4-3.2
Delay disc. indifference point, 8s delay0.20.32.20.50.5-0.3-0.3-0.3-0.4-0.4-0.4-0.3-0.40.30.2-0.3-0.1-0.2-0.2-0.2-0.00.00.81.5-1.0
Indifference point function ln k0.10.33.00.00.0-0.1-0.0-0.00.00.00.2-0.10.1-0.2-0.1-0.30.4-0.30.10.30.3-0.10.91.71.1
Indifference point function log k0.10.33.00.00.0-0.1-0.0-0.00.00.00.2-0.10.1-0.2-0.1-0.30.4-0.30.10.30.3-0.10.91.71.1
Patch foraging total patch changes 0 sec0.81.65.1-1.3-1.31.31.21.21.31.31.01.21.0-1.1-1.2-1.61.40.81.11.21.4-1.22.20.50.7
Patch foraging total patch changes 12 sec0.20.31.6-0.1-0.10.10.00.00.20.1-0.30.2-0.0-0.3-0.4-1.20.30.80.60.50.7-0.51.2-0.70.8
Patch foraging total patch changes 18 sec1.01.53.4-1.3-1.31.31.11.11.31.11.11.21.2-1.3-1.4-1.41.11.51.41.01.2-1.20.8-1.90.2
Patch foraging total patch changes 24 sec0.91.52.3-1.4-1.41.41.31.31.41.40.81.51.0-1.1-1.3-1.51.11.31.20.91.3-1.11.5-0.8-0.7
Patch foraging total patch changes 6 sec0.60.91.7-0.8-0.80.70.60.60.80.60.70.80.8-1.0-1.1-1.30.91.11.11.11.1-1.01.0-1.21.2
Patch foraging time to switch 0 sec0.10.20.7-0.3-0.30.30.20.20.30.30.20.30.3-0.2-0.2-0.50.30.60.50.40.4-0.40.1-0.80.7
Patch foraging water rate 0 sec0.51.12.3-1.1-1.11.11.31.31.11.21.21.21.1-1.1-1.1-0.81.20.30.80.91.0-1.01.50.7-0.2
Patch foraging water rate 12 sec0.10.31.40.50.5-0.5-0.2-0.2-0.5-0.4-0.1-0.5-0.40.30.30.7-0.2-1.2-0.8-0.5-0.50.60.10.6-0.8
Patch foraging water rate 18 sec0.50.84.00.50.5-0.5-0.3-0.3-0.5-0.4-0.9-0.7-1.10.90.80.3-0.7-1.3-1.1-1.1-0.71.20.61.1-2.0
Patch foraging water rate 24 sec0.50.72.9-0.8-0.80.81.01.00.81.00.70.80.7-0.9-0.8-1.00.90.40.70.70.9-0.71.70.3-0.4
Patch foraging water rate 6 sec0.20.31.90.10.1-0.00.20.2-0.1-0.1-0.6-0.2-0.50.30.3-0.1-0.4-0.2-0.3-0.7-0.30.50.91.4-1.2
Seeking ratio, delayed vs. immediate footshock0.50.66.2-0.7-0.70.70.70.70.70.40.70.40.7-0.2-0.40.10.50.60.71.00.5-0.6-0.1-1.02.5
Distance traveled before self-admin0.20.22.60.20.2-0.2-0.2-0.2-0.2-0.3-0.1-0.3-0.20.20.20.2-0.1-0.4-0.3-0.3-0.20.20.11.0-1.6
Distance traveled after self-admin0.60.71.7-0.6-0.60.60.70.70.70.41.30.71.2-1.1-1.3-0.61.20.50.81.10.9-1.00.50.7-0.0
Extensor digitorum longus weight0.31.16.9-0.4-0.40.40.40.40.40.52.20.61.6-0.7-0.62.00.8-1.1-0.30.3-0.2-0.5-2.6-1.20.0
Bone: elastic displacement0.30.40.9-0.6-0.60.60.60.60.60.80.50.70.6-0.6-0.6-0.70.60.60.60.60.6-0.50.3-0.90.4
Bone: elastic work0.10.10.9-0.1-0.10.10.10.10.10.10.30.10.2-0.2-0.1-0.10.4-0.30.00.20.2-0.20.30.10.9
Bone: endosteal estimation0.51.02.5-1.1-1.11.11.01.01.11.11.61.01.4-1.0-0.9-0.11.20.40.81.20.9-1.1-0.1-0.80.7
Bone: endosteal perimeter0.81.72.9-1.6-1.61.61.41.41.61.61.71.41.6-1.4-1.3-0.41.31.01.21.31.1-1.30.1-0.70.4
Epididymis fat weight0.20.73.5-0.6-0.60.70.60.60.70.61.10.71.0-0.9-1.1-0.61.10.20.71.10.9-0.70.50.31.9
Delta time in closed arm before/after self-admin0.20.21.00.10.1-0.1-0.2-0.2-0.1-0.20.6-0.30.4-0.0-0.10.80.1-0.4-0.20.2-0.20.0-1.00.2-0.7
Delta time in open arm before/after self-admin1.71.72.61.31.3-1.3-1.4-1.4-1.3-1.5-1.5-1.3-1.41.41.21.1-1.5-0.8-1.2-1.5-1.41.3-1.2-0.8-1.6
Diff in mean of infusions in LGA sessions0.91.09.00.30.3-0.3-0.3-0.3-0.4-0.8-1.0-0.9-0.91.11.20.9-1.1-0.5-0.7-0.7-1.01.3-1.1-0.4-3.0
Delay discount exponential model param0.91.06.1-0.9-0.90.80.70.70.90.90.80.91.0-0.8-0.7-0.30.51.21.00.90.6-0.6-0.8-2.51.5
Extinction: sum of active levers before priming0.60.61.60.90.9-0.9-0.9-0.9-0.9-0.6-0.3-0.7-0.50.80.71.3-0.5-1.1-0.9-0.6-0.70.6-0.80.3-0.8
Active lever presses in extinction session 60.20.20.6-0.4-0.40.40.60.60.40.60.40.30.5-0.3-0.4-0.10.30.40.40.40.4-0.4-0.3-0.80.4
Bone: final force0.40.62.8-0.6-0.60.60.60.60.60.50.40.50.4-0.5-0.5-1.00.90.30.60.70.9-0.81.70.51.2
Bone: final moment0.40.73.8-0.7-0.70.70.70.70.70.60.50.60.4-0.6-0.5-1.01.00.20.60.70.9-0.81.90.91.3
Food consumed during 24 hour testing period1.21.62.81.41.4-1.4-1.4-1.4-1.4-1.3-0.9-1.3-1.01.31.31.7-1.2-1.4-1.3-1.2-1.41.2-1.60.5-0.6
Glucose1.52.36.7-1.4-1.41.41.41.41.41.41.61.41.2-1.5-1.5-1.51.90.20.91.31.5-1.42.62.31.3
Heart weight1.52.34.3-1.8-1.81.81.71.71.71.62.11.71.9-1.5-1.7-0.31.50.91.21.31.2-1.5-0.4-1.7-0.3
Delay discount hyperbolic model param0.91.06.6-0.9-0.90.80.70.70.90.90.80.91.0-0.8-0.7-0.30.51.21.00.90.6-0.6-0.9-2.61.5
Intermittent access intake day 1-15 change0.51.11.7-0.9-0.90.91.21.20.91.11.11.11.2-1.3-1.2-0.91.01.21.10.81.0-1.10.2-1.00.7
Intermittent access intake escalation0.40.81.4-0.8-0.80.81.11.10.91.00.91.01.0-1.1-1.1-0.80.81.21.00.60.8-0.90.0-1.20.6
Intermittent access intake escalation 22.02.33.6-1.6-1.61.61.81.81.61.61.71.61.8-1.7-1.6-0.91.41.51.51.31.4-1.5-0.0-1.90.9
Intermitt. access day 1 inactive lever presses0.10.31.0-0.0-0.00.0-0.3-0.3-0.1-0.5-1.0-0.7-0.90.60.60.1-0.8-0.2-0.6-0.9-0.70.9-0.4-0.3-0.7
Intermitt. access day 15 inactive lever presses0.91.96.0-1.8-1.81.81.81.81.71.50.71.30.9-1.0-1.0-1.30.81.61.20.91.1-1.00.6-2.40.1
Intermitt. access escalation Index0.30.41.50.00.0-0.00.10.10.10.31.20.51.0-0.7-0.6-0.21.1-0.10.51.20.7-1.00.5-0.70.7
Intermittent access day 1 total infusions0.10.21.20.50.5-0.4-0.7-0.7-0.4-0.4-0.3-0.3-0.30.40.50.3-0.2-0.4-0.3-0.3-0.30.10.21.10.1
Intermittent access day 15 total infusions0.00.00.1-0.1-0.10.10.10.10.10.20.20.20.2-0.2-0.1-0.00.20.20.20.00.1-0.3-0.2-0.4-0.1
Intermittent access terminal intake (last 3 days)0.20.30.6-0.5-0.50.50.60.60.50.60.40.60.6-0.6-0.4-0.40.50.80.70.50.6-0.6-0.1-0.80.1
Intermittent access total infusions0.00.00.10.10.1-0.00.00.0-0.00.20.20.10.1-0.10.10.10.1-0.20.00.00.0-0.1-0.10.0-0.3
Intermittent access day 1 locomotion0.10.10.40.20.2-0.2-0.4-0.4-0.20.0-0.4-0.1-0.40.20.4-0.1-0.2-0.4-0.3-0.3-0.20.30.60.0-0.4
Intermittent access day 15 total locomotion0.20.30.9-0.3-0.30.30.30.30.40.70.30.60.4-0.7-0.5-0.80.60.70.60.50.7-0.70.9-0.11.0
Intermittent access total locomotion0.60.72.1-0.6-0.60.60.60.60.61.00.51.00.6-0.9-0.7-1.30.90.90.90.71.0-0.91.4-0.30.9
Intermittent access standard deviation1.32.74.9-2.1-2.12.12.22.22.01.91.41.71.5-1.5-1.4-1.31.51.41.51.21.5-1.51.1-1.3-0.2
Left kidney weight0.10.76.1-0.4-0.40.40.20.20.40.21.30.20.6-0.0-0.21.10.8-1.8-0.60.3-0.0-0.30.12.50.5
Right kidney weight0.41.83.5-1.6-1.61.61.41.41.51.31.91.41.4-1.2-1.4-0.71.7-0.30.61.31.2-1.21.51.50.8
Cocaine induced anxiety0.30.51.8-0.6-0.60.60.40.40.60.51.00.50.8-0.3-0.20.70.4-0.00.20.30.1-0.5-1.2-1.4-1.3
Post-drug Anxiety0.20.22.0-0.0-0.00.0-0.1-0.10.0-0.1-0.1-0.00.00.30.40.6-0.40.2-0.0-0.2-0.30.1-1.1-1.0-1.4
Baseline Anxiety0.60.72.40.80.8-0.8-0.7-0.7-0.8-0.8-1.5-0.8-1.30.90.8-0.1-1.1-0.0-0.5-0.9-0.71.00.41.2-0.4
Tail length12.046.871.17.47.4-7.3-7.3-7.3-7.3-7.1-5.5-7.0-6.56.96.87.4-6.1-8.4-7.8-6.7-7.16.8-5.06.5-3.2
Length with tail4.821.046.24.84.8-4.8-4.7-4.7-4.7-4.7-2.5-4.6-3.64.44.36.0-3.6-6.8-5.6-4.4-4.94.2-4.04.5-2.2
Length without tail0.20.63.2-0.5-0.50.50.40.40.60.41.80.41.3-0.8-0.70.81.1-1.0-0.00.60.3-0.9-0.4-0.20.6
Times rat made contact with spout0.10.10.40.20.2-0.2-0.1-0.1-0.3-0.2-0.4-0.2-0.30.30.3-0.2-0.2-0.1-0.1-0.2-0.10.20.20.70.4
Lifetime Intake0.00.00.1-0.0-0.00.00.00.00.00.20.10.10.10.00.10.10.1-0.1-0.00.00.0-0.0-0.0-0.4-0.2
Liver weight, left0.10.10.80.10.1-0.1-0.1-0.1-0.2-0.2-0.1-0.2-0.10.20.20.6-0.3-0.4-0.4-0.2-0.40.3-0.90.4-0.1
Liver weight, right0.20.43.60.40.4-0.4-0.4-0.4-0.4-0.4-0.1-0.5-0.30.40.30.30.1-0.9-0.50.1-0.10.10.31.91.1
Locomotor activity0.50.81.4-0.9-0.90.91.11.10.91.00.61.00.8-0.7-0.6-1.00.81.21.11.11.0-1.00.7-0.50.3
Locomotor testing distance1.22.24.4-1.5-1.51.51.61.61.51.50.71.51.0-1.2-1.2-2.11.22.11.81.61.7-1.41.8-0.50.3
Locomotor testing rearing0.10.21.0-0.3-0.30.20.40.40.30.3-0.80.1-0.50.30.2-0.9-0.30.80.40.10.20.11.00.4-0.8
Locomotion in novel chamber0.81.12.80.90.9-1.0-1.1-1.1-0.9-1.2-1.2-1.2-1.20.81.00.1-0.8-1.0-0.9-0.8-0.71.10.61.7-1.7
Locomotion in novel chamber post-restriction0.91.43.2-1.1-1.11.11.11.11.11.00.91.11.1-1.5-1.2-1.61.01.71.41.01.2-1.00.7-1.8-0.1
Fecal boli incidents, locomotor time 12.63.85.3-2.1-2.12.32.32.32.12.12.02.12.1-2.0-2.1-1.41.91.91.91.91.8-2.00.8-2.01.3
Change in fecal boli incidents, locomotor task2.72.73.71.81.8-1.9-1.9-1.9-1.8-1.7-1.8-1.7-1.81.71.61.1-1.6-1.4-1.6-1.6-1.51.6-0.61.7-1.3
Time >=10cm from walls, locomotor time 10.40.41.00.90.9-0.9-0.8-0.8-0.8-0.7-1.0-0.7-0.80.80.70.3-0.7-0.1-0.4-0.4-0.50.6-0.40.10.2
Bouts of movement, locomotor time 10.10.12.0-0.1-0.10.10.10.10.10.20.30.20.2-0.1-0.10.10.3-0.20.10.50.2-0.30.00.21.4
Total resting periods, locomotor time 10.30.33.3-0.4-0.40.30.40.40.40.40.60.40.5-0.3-0.4-0.10.5-0.10.20.70.4-0.50.20.11.8
Rest time, locomotor task time 10.40.50.9-0.8-0.80.80.90.90.80.70.70.70.6-0.8-0.8-0.80.80.30.60.70.7-0.70.6-0.20.2
Distance moved, locomotor task time 10.91.42.11.41.4-1.4-1.4-1.4-1.3-1.1-1.1-1.1-1.21.31.31.0-1.0-1.1-1.1-1.0-1.01.0-0.51.2-1.3
Vertical activity count, locomotor time 10.20.61.41.21.2-1.1-1.1-1.1-1.1-0.6-0.5-0.6-0.50.50.60.6-0.6-0.5-0.5-0.5-0.60.4-0.50.10.8
Time >=10cm from walls, locomotor time 20.60.91.61.21.2-1.1-1.1-1.1-1.1-1.0-1.3-1.0-1.20.90.80.2-0.9-0.7-0.8-0.7-0.71.10.31.10.6
Bouts of movement, locomotor time 20.10.10.3-0.4-0.40.40.30.30.30.20.10.20.2-0.3-0.2-0.50.20.30.30.40.3-0.40.30.10.5
Total resting periods, locomotor time 20.10.10.2-0.4-0.40.40.30.30.40.20.10.20.2-0.3-0.2-0.50.20.40.40.40.3-0.40.2-0.20.3
Rest time, locomotor task time 21.21.65.11.01.0-1.1-1.0-1.0-1.0-1.3-1.1-1.2-1.01.41.21.4-1.4-0.6-1.0-1.1-1.31.1-2.3-0.5-2.1
Distance moved, locomotor task time 20.20.32.00.60.6-0.6-0.6-0.6-0.6-0.20.1-0.2-0.20.10.20.20.1-1.0-0.5-0.3-0.20.30.61.40.2
Vertical activity count, locomotor time 20.30.42.70.50.5-0.3-0.3-0.3-0.30.20.60.30.3-0.6-0.4-0.40.6-0.7-0.10.10.3-0.31.21.21.6
Light reinforcement 10.30.62.4-0.7-0.70.60.50.50.70.70.10.80.4-0.7-0.6-1.60.51.31.00.80.9-0.51.4-0.20.5
Light reinforcement 20.00.10.4-0.1-0.10.10.10.10.10.2-0.00.20.1-0.2-0.2-0.70.20.30.30.30.3-0.10.7-0.3-0.1
Bone: marrow area0.40.82.0-0.9-0.90.90.80.80.91.01.40.91.3-0.9-0.8-0.01.10.30.71.00.7-1.0-0.2-0.80.6
Bone: maximum diameter0.81.51.9-1.4-1.41.41.31.31.41.31.21.21.2-1.1-1.1-1.01.31.01.21.31.2-1.31.3-0.11.2
Bone: maximum force0.61.02.6-1.0-1.01.00.90.91.00.81.10.81.0-0.9-0.8-0.81.30.20.81.01.1-1.21.40.61.6
Bone: maximum moment0.71.23.2-1.0-1.01.10.90.91.10.91.30.91.1-1.0-0.9-0.91.50.10.81.21.2-1.31.80.91.8
Mean time between licks in bursts0.10.10.6-0.2-0.20.20.30.30.20.30.60.30.6-0.3-0.30.30.30.10.20.40.1-0.4-0.8-0.50.6
Mean num. licks in bursts0.00.10.50.30.3-0.2-0.2-0.2-0.3-0.2-0.1-0.1-0.20.20.20.2-0.1-0.4-0.30.1-0.20.2-0.10.7-0.1
Cd content in liver0.20.22.30.10.1-0.10.10.1-0.20.00.1-0.00.1-0.00.00.4-0.20.20.0-0.0-0.20.2-1.4-1.5-0.2
Co content in liver0.10.20.90.10.1-0.1-0.1-0.1-0.10.10.40.00.20.00.00.80.0-0.5-0.3-0.1-0.30.1-1.0-0.8-0.7
Cu content in liver2.73.27.01.81.8-1.8-1.7-1.7-1.8-2.0-1.7-2.0-1.51.92.02.0-2.0-1.1-1.5-1.5-1.81.6-2.7-1.5-1.5
Fe content in liver0.60.72.00.70.7-0.7-0.6-0.6-0.7-0.7-0.3-0.9-0.50.80.91.4-0.7-1.2-1.0-0.6-1.00.8-1.20.6-0.9
K content in liver0.10.10.4-0.5-0.50.50.40.40.40.30.20.30.0-0.1-0.2-0.10.2-0.2-0.1-0.10.1-0.10.60.5-0.6
Mg content in liver2.22.23.21.41.4-1.4-1.4-1.4-1.5-1.5-1.5-1.6-1.61.61.61.4-1.5-1.6-1.7-1.8-1.61.6-0.90.9-1.4
Mn content in liver3.74.15.82.02.0-2.0-2.1-2.1-2.0-2.2-2.4-2.2-2.22.22.21.7-2.4-1.4-2.0-2.4-2.22.2-1.80.5-1.6
Na content in liver1.71.82.6-1.5-1.51.51.61.61.51.41.11.31.2-1.4-1.3-1.51.21.51.41.21.3-1.31.1-1.30.3
Rb content in liver0.60.72.50.90.9-0.9-0.9-0.9-0.9-0.8-1.2-0.8-0.90.80.7-0.0-0.90.1-0.4-0.7-0.50.7-0.6-1.6-0.5
Se content in liver0.50.61.9-0.8-0.80.80.90.90.80.70.10.60.3-0.6-0.6-1.30.61.00.90.70.9-0.71.40.50.6
Sr content in liver1.81.52.91.31.3-1.3-1.3-1.3-1.3-1.3-0.8-1.2-1.11.21.21.5-1.0-1.7-1.5-1.4-1.31.2-1.21.0-0.6
Zn content in liver0.30.31.9-0.6-0.60.60.70.70.50.6-0.00.50.0-0.4-0.5-1.10.30.50.40.00.5-0.31.40.6-0.5
Bone: minimum diameter0.10.21.3-0.4-0.40.40.30.30.40.40.80.40.6-0.3-0.20.30.6-0.50.10.50.3-0.50.51.10.3
Time in familiar zone, hab. session 10.80.82.00.80.8-0.8-0.8-0.8-0.8-1.0-1.3-1.0-1.01.01.10.6-1.20.1-0.5-0.7-0.80.8-1.4-1.0-0.4
Time in novel zone, hab. session 13.23.25.8-1.9-1.91.91.91.91.91.91.61.81.6-1.9-1.8-2.11.91.41.71.81.9-1.92.4-0.20.9
Total zone transitions, hab. session 16.49.012.33.13.1-3.1-3.1-3.1-3.1-3.0-2.5-3.0-2.83.13.13.5-3.0-3.2-3.2-3.1-3.32.9-3.21.2-2.6
Total locomotion distance, hab. session 12.53.54.72.02.0-2.0-2.0-2.0-2.0-2.2-2.0-2.1-2.02.02.11.7-2.0-1.8-2.0-2.0-2.01.9-1.50.5-1.1
Locomotion velocity, hab. session 13.34.75.82.32.3-2.3-2.3-2.3-2.3-2.3-2.0-2.2-2.22.32.22.2-2.2-2.3-2.4-2.3-2.32.2-1.81.1-1.3
Time in familiar zone, hab. session 20.40.42.5-0.6-0.60.60.60.60.50.5-0.00.50.3-0.5-0.5-0.90.11.20.80.30.5-0.30.0-1.6-0.0
Time in novel zone, hab. session 20.20.22.50.20.2-0.2-0.2-0.2-0.2-0.10.1-0.2-0.10.20.20.10.2-0.7-0.3-0.0-0.0-0.10.81.60.5
Total zone transitions, hab. session 21.72.22.81.71.7-1.7-1.6-1.6-1.6-1.6-1.3-1.5-1.31.51.61.7-1.5-1.4-1.5-1.4-1.51.4-1.6-0.0-0.6
Total locomotion distance, hab. session 20.00.10.40.30.3-0.3-0.3-0.3-0.3-0.3-0.1-0.2-0.10.10.20.2-0.1-0.1-0.1-0.1-0.10.1-0.3-0.40.7
Locomotion velocity, hab. session 20.10.10.40.40.4-0.4-0.4-0.4-0.3-0.4-0.1-0.3-0.20.20.30.4-0.1-0.4-0.3-0.2-0.20.2-0.3-0.10.7
Novel to familiar place preference ratio0.80.92.80.80.8-0.8-0.8-0.8-0.8-0.8-0.2-0.9-0.50.90.91.5-0.5-1.6-1.1-0.6-0.90.8-0.61.7-0.4
Novelty place preference0.91.03.50.90.9-0.9-1.0-1.0-0.9-1.0-0.4-1.1-0.71.01.01.4-0.6-1.6-1.2-0.7-1.00.8-0.41.9-0.2
Time in novel zone, NPP test0.80.83.30.80.8-0.8-0.9-0.9-0.8-0.9-0.5-1.0-0.70.91.01.1-0.6-1.4-1.0-0.6-0.80.7-0.11.8-0.2
Total zone transitions, NPP test3.55.06.52.52.5-2.5-2.5-2.5-2.5-2.6-2.0-2.3-2.22.22.32.2-2.1-2.5-2.4-2.4-2.32.1-1.61.2-1.2
Total locomotion distance, NPP test0.81.21.81.21.2-1.2-1.2-1.2-1.2-1.3-1.1-1.2-1.21.01.10.8-1.1-1.1-1.2-1.3-1.11.0-0.40.6-0.4
Locomotion velocity, NPP test1.41.92.71.51.5-1.5-1.5-1.5-1.5-1.7-1.2-1.5-1.31.31.41.3-1.3-1.6-1.6-1.6-1.51.3-1.00.7-0.7
Intraocular pressure1.11.53.21.31.3-1.3-1.6-1.6-1.3-1.5-0.6-1.3-0.81.21.21.8-1.0-1.5-1.3-0.8-1.20.9-1.70.60.0
Delta distance traveled before/after self-admin0.50.61.4-0.5-0.50.50.60.60.60.41.10.61.0-1.0-1.2-0.50.90.70.80.90.8-0.9-0.0-0.51.1
Delta ambulatory time before/after self-admin0.60.82.5-0.7-0.70.70.70.70.70.51.10.81.1-1.1-1.2-0.71.10.60.80.90.9-1.00.6-0.41.6
Parametrial fat weight0.20.42.6-0.2-0.20.20.10.10.30.30.30.40.3-0.4-0.4-0.90.70.10.40.70.7-0.61.61.20.9
Pavlov. Cond. lever latency1.31.64.0-1.2-1.21.21.21.21.21.22.01.31.8-1.4-1.3-0.31.70.41.11.71.3-1.50.5-0.31.4
Pavlov. Cond. magazine entry latency0.30.42.4-0.0-0.00.00.10.1-0.00.0-1.00.1-0.60.0-0.0-1.6-0.21.10.50.10.5-0.01.3-0.00.8
Pavlov. Cond. change in total contacts1.92.05.51.41.4-1.4-1.4-1.4-1.5-1.5-2.3-1.5-2.01.71.60.2-1.8-0.4-1.0-1.4-1.21.5-0.20.9-0.5
Pavlov. Cond. index score0.60.73.30.80.8-0.8-0.7-0.7-0.8-0.7-1.8-0.7-1.40.90.8-0.8-1.10.5-0.3-0.9-0.40.90.50.2-0.3
Pavlov. Cond. latency score0.60.83.10.80.8-0.8-0.8-0.8-0.9-0.8-1.8-0.8-1.40.90.8-0.5-1.20.2-0.4-1.0-0.61.00.40.3-0.4
Pavlov. Cond. lever contacts1.92.25.51.51.5-1.5-1.4-1.4-1.5-1.5-2.3-1.5-2.01.61.60.4-2.0-0.4-1.2-1.9-1.51.8-0.80.0-1.4
Pavlov. Cond. magazine entry number0.40.52.9-0.5-0.50.40.40.40.50.41.70.41.2-0.5-0.51.30.8-1.0-0.20.50.0-0.6-0.9-0.2-0.2
Pavlov. Cond. intertrial magazine entries0.60.82.10.80.8-0.8-0.9-0.9-0.7-1.0-0.4-1.0-0.50.91.01.5-0.6-1.3-1.0-0.6-0.90.5-0.90.8-0.3
Pavlov. Cond. lever-magazine prob. diff.0.60.73.40.80.8-0.8-0.7-0.7-0.8-0.7-1.9-0.7-1.40.90.8-0.9-1.10.5-0.2-0.9-0.40.80.80.4-0.2
Pavlov. Cond. response bias0.70.84.00.80.8-0.8-0.8-0.8-0.8-0.9-2.0-0.8-1.50.90.9-0.8-1.30.6-0.3-1.0-0.51.00.40.1-0.4
Pavlov. Cond. lever latency0.50.71.50.70.7-0.7-0.8-0.8-0.8-0.7-0.7-0.9-0.80.90.91.0-0.9-0.8-0.8-0.8-0.90.8-1.20.0-0.9
Pavlov. Cond. magazine entry latency0.20.31.00.50.5-0.5-0.5-0.5-0.5-0.4-0.3-0.4-0.50.50.50.5-0.3-0.9-0.7-0.4-0.50.6-0.11.0-0.2
Pavlov. Cond. change in total contacts0.20.30.8-0.4-0.40.40.40.40.40.30.30.50.4-0.6-0.6-0.90.50.70.60.50.6-0.50.8-0.20.9
Pavlov. Cond. index score0.30.40.9-0.5-0.50.50.50.50.50.50.60.70.5-0.7-0.7-0.80.70.30.50.60.7-0.51.00.30.8
Pavlov. Cond. latency score0.10.20.7-0.3-0.30.30.30.30.30.30.50.50.4-0.5-0.5-0.60.60.00.30.40.5-0.30.90.60.6
Pavlov. Cond. lever contacts0.40.61.3-0.7-0.70.70.70.70.70.70.60.80.6-0.8-0.8-1.10.80.80.80.70.8-0.71.1-0.30.7
Pavlov. Cond. magazine entry number0.10.10.7-0.0-0.00.00.00.0-0.0-0.1-0.2-0.2-0.10.20.20.4-0.40.2-0.0-0.2-0.30.1-0.9-0.8-0.5
Pavlov. Cond. intertrial magazine entries1.82.75.01.71.7-1.7-1.7-1.7-1.7-1.6-1.3-1.8-1.41.71.72.1-1.8-1.6-1.7-1.6-1.91.6-2.20.6-0.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.5-0.50.50.50.50.50.50.70.70.6-0.7-0.7-0.80.80.30.50.60.7-0.61.00.30.8
Pavlov. Cond. response bias0.60.92.3-0.8-0.80.80.90.90.90.80.70.90.7-1.0-1.0-1.31.00.91.00.91.0-0.81.5-0.10.8
Time in closed arm before self-admin1.62.13.7-1.7-1.71.71.61.61.61.60.71.60.9-1.3-1.2-1.91.01.51.41.01.4-1.11.8-1.41.2
Time in closed arm after self-admin1.21.21.9-1.4-1.41.41.31.31.31.11.31.11.2-1.1-1.1-0.71.20.71.01.21.0-1.10.5-0.80.6
Time in open arm before self-admin0.40.41.81.01.0-1.0-0.9-0.9-0.8-0.80.2-0.80.20.10.30.9-0.1-0.4-0.30.1-0.40.0-1.30.00.4
Time in open arm after self-admin2.62.84.42.12.1-2.1-2.0-2.0-2.0-2.0-1.5-1.8-1.51.51.51.6-1.7-1.1-1.5-1.6-1.71.4-2.0-0.2-1.0
Bone: periosteal estimation0.51.11.6-1.2-1.21.21.11.11.21.21.31.01.2-0.9-0.8-0.61.20.40.91.11.0-1.21.00.01.0
Bone: periosteal perimeter0.71.22.1-1.4-1.41.41.31.31.41.31.41.11.3-1.1-1.0-0.51.20.71.01.11.0-1.20.7-0.20.4
Bone: post-yield work0.10.20.5-0.4-0.40.50.30.30.40.10.70.30.6-0.3-0.20.00.6-0.10.30.70.4-0.60.20.40.5
Progressive ratio test 1 active lever presses0.40.51.71.01.0-1.0-0.9-0.9-0.9-0.6-0.5-0.5-0.60.40.50.0-0.2-0.8-0.5-0.3-0.30.40.61.30.9
Progressive ratio test 1 breakpoint0.40.51.50.90.9-0.9-0.9-0.9-0.9-0.5-0.4-0.5-0.50.40.50.0-0.2-0.7-0.5-0.3-0.20.40.61.21.0
Progressive ratio test 1 inactive lever presses0.10.11.0-0.4-0.40.40.40.40.40.40.10.40.1-0.3-0.2-0.40.20.10.10.10.2-0.10.4-1.0-0.1
Progressive ratio test 2 active lever presses0.00.10.20.40.4-0.4-0.2-0.2-0.4-0.1-0.3-0.1-0.20.10.1-0.1-0.1-0.1-0.1-0.2-0.00.10.10.10.3
Progressive ratio test 2 breakpoint0.10.10.20.40.4-0.4-0.3-0.3-0.4-0.2-0.3-0.1-0.30.20.2-0.1-0.1-0.2-0.2-0.2-0.10.20.20.30.3
Progressive ratio test 2 inactive lever presses0.10.11.3-0.3-0.30.30.20.20.20.20.1-0.0-0.00.20.10.4-0.1-0.3-0.2-0.2-0.20.1-0.4-0.5-1.1
Incentive Sensitization - Responses0.10.10.8-0.2-0.20.20.40.40.20.4-0.10.4-0.1-0.1-0.3-0.3-0.10.40.1-0.20.10.10.1-0.5-0.9
Incentive Sensitization - Breakpoint0.10.20.6-0.4-0.40.40.60.60.40.60.10.60.1-0.2-0.4-0.40.10.50.30.00.3-0.10.2-0.5-0.7
Sum of active levers in priming session hrs 5-63.73.54.42.02.0-2.0-1.9-1.9-2.0-1.8-1.9-1.8-1.92.01.91.9-2.0-1.7-1.8-1.9-1.92.1-1.71.3-1.6
Progressive ratio0.50.86.70.00.0-0.0-0.2-0.2-0.2-0.6-0.9-0.5-0.91.00.70.8-1.1-0.5-0.8-1.1-1.01.3-0.9-0.1-2.6
Food seeking constrained by brief footshock0.80.92.1-1.0-1.01.01.01.01.00.80.70.80.8-0.9-0.8-1.11.00.81.01.01.1-0.71.10.61.4
Seeking ratio, punishment vs. effort0.40.66.20.30.3-0.3-0.1-0.1-0.10.20.60.10.6-0.8-0.4-0.60.90.30.71.00.8-0.90.71.02.5
Retroperitoneal fat weight0.52.35.1-1.4-1.41.41.31.31.41.21.41.31.3-1.5-1.6-1.91.90.81.31.71.7-1.42.30.52.2
Reaction time number correct0.20.42.10.10.1-0.2-0.2-0.2-0.2-0.3-0.3-0.5-0.40.50.70.8-0.6-0.7-0.6-1.1-0.70.6-0.8-0.4-1.5
Reaction time mean minus median0.30.72.31.11.1-1.1-1.2-1.2-1.0-1.0-0.6-0.9-0.50.50.50.5-0.6-0.2-0.4-0.1-0.50.3-0.8-0.61.5
Reaction time mean minus median AUC0.30.92.41.31.3-1.3-1.4-1.4-1.2-1.1-1.0-1.0-0.80.70.60.1-0.80.1-0.3-0.4-0.50.4-0.6-0.71.5
Reaction time num false alarms0.20.30.70.50.5-0.5-0.5-0.5-0.5-0.4-0.7-0.4-0.70.40.4-0.0-0.5-0.2-0.4-0.8-0.40.50.40.9-0.8
Reaction time num false alarms AUC0.20.40.80.60.6-0.6-0.6-0.6-0.6-0.6-0.7-0.5-0.70.50.50.1-0.6-0.4-0.5-0.9-0.50.50.40.9-0.9
Reaction time trials correct on left0.20.42.10.10.1-0.2-0.2-0.2-0.2-0.3-0.3-0.5-0.40.50.70.8-0.6-0.7-0.6-1.1-0.70.6-0.8-0.4-1.5
Reaction time trials on left0.20.41.90.20.2-0.2-0.3-0.3-0.3-0.3-0.3-0.5-0.40.50.80.8-0.6-0.7-0.6-1.0-0.70.6-0.8-0.4-1.4
Reaction time mean0.30.55.50.40.4-0.4-0.4-0.4-0.2-0.20.1-0.10.3-0.2-0.2-0.30.20.80.60.90.4-0.6-0.5-1.22.3
Reaction time mean AUC0.30.55.90.50.5-0.5-0.5-0.5-0.4-0.30.1-0.10.3-0.2-0.2-0.20.10.80.50.90.3-0.6-0.6-1.42.4
Median of all reaction times0.50.75.1-0.1-0.10.10.10.10.20.30.40.40.6-0.6-0.6-0.70.51.31.01.20.7-0.9-0.1-1.32.3
Reaction time omissions0.40.63.70.90.9-0.9-1.1-1.1-0.8-0.8-0.5-0.7-0.50.60.60.2-0.2-0.4-0.30.2-0.20.10.30.71.9
Reaction time false alarm rate0.10.11.10.20.2-0.3-0.2-0.2-0.2-0.1-0.4-0.0-0.30.0-0.1-0.5-0.00.20.0-0.10.10.01.01.0-0.1
Reaction time premature initiation rate0.30.40.60.70.7-0.8-0.7-0.7-0.7-0.8-0.6-0.6-0.70.40.40.0-0.4-0.8-0.6-0.4-0.40.50.40.00.6
Reaction time premature initiations0.50.81.51.01.0-1.0-1.0-1.0-1.0-1.1-0.8-1.0-0.90.80.90.7-0.8-1.2-1.1-1.1-0.91.0-0.3-0.0-0.3
Std. dev. reaction times0.30.53.80.90.9-0.9-1.0-1.0-0.8-0.7-0.4-0.6-0.30.30.30.1-0.30.0-0.10.2-0.2-0.1-0.3-0.42.0
Reaction time trials completed0.20.41.90.20.2-0.2-0.3-0.3-0.3-0.3-0.3-0.5-0.40.50.80.8-0.6-0.7-0.6-1.0-0.70.6-0.8-0.4-1.4
Reaction time trials AUC0.20.42.00.20.2-0.2-0.3-0.3-0.3-0.4-0.4-0.5-0.40.60.80.7-0.7-0.6-0.6-1.1-0.70.6-0.8-0.4-1.4
Run reversals in cocaine runway, females0.30.32.50.60.6-0.6-0.4-0.4-0.5-0.20.3-0.10.10.10.20.80.1-0.9-0.4-0.0-0.2-0.1-0.31.6-0.9
Run reversals in cocaine runway, males0.80.83.6-0.7-0.70.70.80.80.70.80.30.90.7-0.8-0.9-1.00.41.71.20.50.8-1.00.0-1.90.3
Latency to leave start box in cocaine runway2.83.14.7-2.2-2.22.22.12.12.11.72.11.72.0-1.8-1.8-0.91.71.31.61.71.5-1.40.1-2.11.3
Latency to leave start box in cocaine runway, F3.54.06.4-2.3-2.32.32.22.22.31.92.52.02.4-2.2-2.2-1.22.11.41.81.91.8-2.00.7-1.91.3
Latency to leave start box in cocaine runway, M0.50.51.2-1.0-1.01.00.90.90.90.60.60.50.6-0.4-0.40.10.50.40.50.80.4-0.1-0.5-1.10.5
Std. dev. time between licks in bursts1.21.62.0-1.4-1.41.41.31.31.41.31.41.31.4-1.3-1.3-0.91.21.21.31.31.2-1.30.3-1.30.8
Total sessions with >9 infusions0.10.20.4-0.3-0.30.30.40.40.30.50.40.40.3-0.3-0.4-0.40.50.10.20.40.4-0.30.70.10.6
Short access day 1 total inactive lever presses3.54.58.11.71.7-1.7-1.8-1.8-1.8-2.0-2.8-2.1-2.72.72.51.7-2.6-1.6-2.2-2.5-2.32.5-1.50.2-2.8
Short access day 10 total inactive lever presses0.30.76.2-1.1-1.11.11.01.00.90.50.20.40.5-0.4-0.4-0.3-0.01.10.60.20.2-0.2-0.9-2.5-0.4
Short access day 1 total infusions0.10.10.5-0.4-0.40.40.30.30.40.30.20.20.2-0.1-0.3-0.20.20.20.20.20.2-0.10.2-0.7-0.4
Short access day 10 total infusions0.50.61.2-0.9-0.90.90.80.80.91.10.81.10.8-0.8-0.9-0.80.80.70.80.70.8-0.70.70.10.4
Short access total infusions0.20.20.4-0.5-0.50.50.40.40.50.60.60.60.5-0.3-0.4-0.30.50.20.40.50.5-0.40.5-0.60.3
Short access day 1 locomotion1.72.13.1-1.8-1.81.81.81.81.71.81.21.51.2-1.4-1.4-1.61.31.21.21.11.4-1.21.6-1.40.2
Short access day 10 total locomotion1.73.16.8-1.8-1.81.81.81.81.82.31.22.11.3-1.8-1.6-2.41.61.81.81.31.8-1.42.6-0.41.0
Short access total locomotion1.62.03.4-1.6-1.61.61.61.61.61.81.21.71.1-1.3-1.3-1.51.31.21.21.01.3-1.21.7-1.10.7
One hour access (0.3 mA shock)0.40.51.11.01.0-1.0-0.7-0.7-1.0-0.6-0.7-0.5-0.70.70.60.4-0.6-0.4-0.6-0.6-0.60.7-0.4-0.1-0.8
Compulsive drug intake3.94.76.42.52.5-2.5-2.3-2.3-2.5-2.4-2.3-2.1-2.42.42.21.6-2.2-1.9-2.2-1.9-2.12.3-1.31.3-1.6
One hour access (shock baseline)1.32.02.8-1.5-1.51.51.51.51.51.71.51.51.6-1.5-1.5-1.11.51.21.51.31.4-1.51.0-1.10.8
Social response proportion0.80.94.10.90.9-0.9-0.9-0.9-0.9-0.8-0.7-0.9-0.90.90.90.6-0.5-1.5-1.1-0.8-0.70.70.82.0-0.1
Social responses0.10.11.40.10.1-0.1-0.1-0.1-0.1-0.0-0.1-0.1-0.20.20.20.00.1-0.4-0.10.00.00.10.81.2-0.1
Social time0.10.10.5-0.1-0.10.10.10.10.10.20.00.10.20.00.00.1-0.00.60.40.50.1-0.1-0.7-0.6-0.1
Soleus weight1.13.35.1-1.8-1.81.81.81.81.71.81.71.91.7-2.0-1.9-2.22.11.31.71.92.0-1.82.30.32.1
Bone: stiffness0.10.21.2-0.2-0.20.20.10.10.20.10.40.10.3-0.3-0.2-0.40.5-0.10.20.30.4-0.50.90.51.1
Tibialis anterior weight0.31.14.31.11.1-1.1-1.1-1.1-1.1-1.1-0.1-0.8-0.40.60.81.6-0.6-1.5-1.1-0.8-1.10.8-2.1-0.30.1
Time to tail flick, vehicle, before self-admin4.64.87.22.12.1-2.1-2.1-2.1-2.2-2.0-2.5-2.1-2.52.72.62.1-2.5-1.7-2.1-2.3-2.32.4-2.10.4-2.2
Time to tail flick, vehicle, after self-admin0.40.56.0-0.4-0.40.40.40.40.40.20.20.20.4-0.3-0.3-0.20.20.70.50.30.3-0.4-0.9-2.4-0.9
Time to tail flick, test, before self-admin0.20.20.6-0.5-0.50.50.40.40.50.50.40.50.4-0.2-0.10.20.20.30.30.20.2-0.3-0.4-0.3-0.8
Time to tail flick, test, after self-admin0.20.21.6-0.1-0.10.10.10.10.20.30.30.20.4-0.4-0.3-0.30.40.30.40.50.4-0.50.10.61.3
Delta time to tail flick, vehicle, before/after SA3.53.44.3-1.9-1.91.91.91.91.91.71.71.81.8-2.1-2.0-2.01.81.92.01.82.0-2.01.2-1.71.0
Delta time to tail flick, test, before/after SA0.40.41.40.80.8-0.8-0.7-0.7-0.7-0.6-0.7-0.7-0.80.40.4-0.3-0.3-0.6-0.5-0.4-0.30.60.71.20.9
Tibia length0.30.82.5-0.7-0.70.70.70.70.80.91.60.91.2-0.9-0.7-0.01.3-0.40.40.80.8-1.10.90.70.9
Ambulatory time before self-admin0.10.11.40.10.1-0.1-0.0-0.0-0.0-0.10.2-0.10.1-0.1-0.10.10.1-0.2-0.0-0.10.0-0.1-0.00.5-1.2
Ambulatory time after self-admin0.81.03.0-0.7-0.70.70.80.80.70.51.70.81.5-1.4-1.6-0.51.50.30.81.21.0-1.20.50.60.7
Bone: tissue strength0.00.00.2-0.2-0.20.20.10.10.10.10.40.20.3-0.3-0.20.10.20.10.10.30.1-0.1-0.40.20.2
Total heroin consumption1.21.52.11.21.2-1.2-1.2-1.2-1.3-1.2-1.5-1.3-1.31.41.41.1-1.4-0.7-1.0-1.1-1.21.3-1.30.8-1.0
Bone: trabecular number1.22.05.7-1.6-1.61.51.41.41.51.30.61.20.8-1.2-1.1-2.31.31.61.51.41.7-1.32.4-0.00.9
Bone: trabecular spacing0.20.31.70.40.4-0.4-0.3-0.3-0.4-0.2-0.1-0.2-0.10.10.00.5-0.50.0-0.3-0.5-0.50.4-1.1-1.3-1.1
Bone: trabecular thickness2.43.04.2-1.9-1.91.91.81.81.91.72.01.71.8-1.6-1.6-1.42.10.91.51.81.8-1.91.8-0.21.9
Bone: trabecular tissue density0.10.10.30.40.4-0.4-0.3-0.3-0.4-0.4-0.3-0.3-0.30.20.20.2-0.4-0.3-0.4-0.6-0.40.5-0.5-0.20.1
Water consumed over 24 hours0.10.20.40.50.5-0.5-0.4-0.4-0.5-0.5-0.5-0.4-0.40.50.50.4-0.5-0.3-0.4-0.6-0.40.5-0.5-0.1-0.2
Number of responses in last shaping day0.20.21.8-0.5-0.50.50.50.50.50.30.40.30.4-0.3-0.40.00.20.60.30.10.2-0.3-0.6-1.40.1