Hub : Genes

Snx20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Snx20 0.07 0.04 5.6e-09 0.07 0.03 0.06 0.02 5.3e-08 3.1e-04 1.0e-07 1.5e-03
2 pVTA gene expression Snx20 0.06 0.04 1.8e-05 0.04 0.03 0.03 0.04 1.5e-04 2.3e-03 1.9e-03 3.3e-04
3 Adipose mRNA stability Snx20 0.16 0.08 0.0e+00 0.16 0.05 0.18 -0 5.5e-18 2.1e-06 3.9e-19 5.6e-01
4 Brain mRNA stability Snx20 0.11 0.06 1.3e-15 0.16 0.17 0.17 0.17 8.3e-15 6.3e-16 2.3e-15 1.2e-15
5 LHb gene expression Snx20 0.3 0.14 8.2e-06 0.17 0.09 0.1 0.16 6.6e-05 4.8e-03 2.4e-03 1.5e-04
6 BLA mRNA stability Snx20 0.08 0.05 2.3e-04 0.06 0.07 0.04 0.06 4.6e-04 2.0e-04 3.0e-03 4.1e-04
7 PL mRNA stability Snx20 0.02 0.02 5.0e-03 0.02 0.01 0.01 0.01 5.9e-03 1.4e-02 1.5e-02 3.3e-02
8 Brain gene expression Snx20 0.17 0.08 0.0e+00 0.24 0.24 0.24 0.24 4.5e-22 5.3e-22 6.0e-22 5.8e-22
9 NAcc gene expression Snx20 0.06 0.04 4.9e-09 0.05 0.05 0.04 0.05 1.8e-08 3.3e-08 2.6e-06 2.0e-08
10 BLA gene expression Snx20 0.04 0.03 7.5e-03 0.03 0.02 0.01 0.02 1.2e-02 2.0e-02 5.5e-02 4.7e-02
11 Adipose gene expression Snx20 0.06 0.05 2.3e-06 0.06 -0 0.05 -0 7.9e-07 8.3e-01 3.7e-06 4.0e-01
12 NAcc mRNA stability Snx20 0.04 0.02 4.6e-06 0.03 0.03 0.02 0.03 2.7e-05 2.0e-05 2.6e-04 1.0e-04
13 IC gene expression Snx20 0.06 0.05 9.3e-03 0.03 0.02 0.01 0.02 2.4e-02 3.8e-02 9.7e-02 5.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.52.76.6-2.6-2.1-1.82.0-1.51.6-1.8-1.4-1.4-1.3-1.41.0-1.1
Area under the delay curve0.30.50.70.90.70.8-0.80.7-0.70.80.70.60.60.7-0.50.5
BMI with tail2.37.910.63.13.32.4-3.02.8-2.82.82.92.72.82.8-1.92.8
BMI without tail0.21.11.71.11.30.7-1.00.7-0.91.01.31.11.21.3-0.50.9
Body weight0.42.04.62.21.91.0-1.71.4-1.21.41.31.21.31.3-0.31.3
Weight adjusted by age1.44.05.72.02.11.7-2.22.3-2.11.91.91.91.91.8-1.52.4
Bone surface0.51.12.3-1.5-1.1-1.31.2-1.11.1-1.1-0.7-0.8-0.7-0.70.9-0.7
Bone volume1.73.45.2-2.3-1.9-2.22.0-1.81.9-1.9-1.7-1.7-1.6-1.71.7-1.2
Breakpoint value in progressive ratio session0.40.71.9-1.0-1.1-0.41.0-0.70.7-0.7-0.8-0.8-0.5-0.80.0-1.4
Number of licking bursts0.20.61.1-0.7-0.8-0.60.8-0.70.8-0.8-0.8-0.8-0.8-0.80.6-1.0
Context. condit. distance diff. score3.54.37.51.91.72.7-1.92.0-2.22.32.02.02.02.0-2.70.6
Locomotion velocity, session 10.30.31.20.10.2-0.50.5-1.10.7-0.4-0.2-0.3-0.2-0.21.0-0.6
Locomotion distance, session 10.00.00.4-0.10.10.30.2-0.00.1-0.10.00.10.00.0-0.2-0.6
Locomotion velocity, session 20.00.00.20.00.00.20.1-0.3-0.00.20.20.20.20.2-0.3-0.4
Locomotion distance, session 20.20.20.60.30.40.8-0.30.5-0.40.30.50.50.50.5-0.7-0.1
Locomotion velocity, session 32.42.83.91.92.01.6-1.81.6-1.71.71.61.71.61.6-1.21.6
Locomotion distance, session 30.40.41.01.00.90.8-0.80.7-0.60.60.50.60.50.5-0.30.4
Stereotopy head waving bouts, day 31.11.31.91.11.41.1-1.10.8-1.11.11.31.21.31.3-1.00.8
Stereotopy head waving duration, day 31.41.72.31.21.41.4-1.21.0-1.31.31.51.41.51.5-1.20.9
Locomotion velocity, session 71.11.23.50.40.61.6-0.81.3-1.21.11.11.21.11.1-1.90.2
Locomotion distance, session 70.50.62.0-1.3-1.40.10.8-0.20.3-0.5-0.7-0.7-0.7-0.7-0.7-1.0
Stereotopy head waving bouts, day 71.61.84.51.92.10.9-1.51.0-1.11.21.41.41.41.4-0.31.2
Stereotopy head waving duration, day 70.20.31.30.91.1-0.2-0.4-0.10.10.10.40.30.40.40.90.3
Locomotion velocity, session 81.01.23.50.60.61.8-0.70.9-1.11.11.11.21.11.1-1.9-0.3
Locomotion distance, session 81.52.25.21.21.22.3-1.11.4-1.51.51.41.51.41.4-2.3-0.2
Degree of sensitization distance0.50.62.0-1.4-1.4-0.20.9-0.40.4-0.5-0.5-0.6-0.5-0.5-0.7-0.8
Degree of sensitization stereotypy1.41.53.61.71.90.8-1.31.0-0.91.11.31.31.31.3-0.11.2
Conditioned locomotion0.20.20.5-0.5-0.7-0.60.4-0.50.4-0.4-0.5-0.6-0.5-0.50.4-0.1
Cocaine response after cond. corrected0.91.42.80.80.61.5-1.01.4-1.31.31.11.11.11.1-1.70.7
Cocaine response after cond. not corrected0.60.91.60.90.71.2-0.91.3-1.01.01.00.90.91.0-1.10.7
Cocaine response before conditioning1.31.54.1-0.6-0.3-1.61.0-1.21.4-1.4-1.2-1.2-1.2-1.22.0-0.8
Saline control response1.82.46.9-2.4-1.9-0.72.0-1.61.4-1.5-1.0-1.1-0.9-1.00.1-2.6
Bone: connectivity density1.52.37.2-2.7-2.3-1.51.9-1.21.3-1.5-1.1-1.2-1.1-1.10.4-1.1
Bone: cortical apparent density0.10.20.8-0.3-0.20.5-0.10.4-0.40.30.30.30.30.3-0.90.3
Bone: cortical area0.20.30.4-0.4-0.4-0.60.5-0.60.6-0.5-0.5-0.5-0.5-0.50.6-0.6
Bone: cortical porosity0.10.20.60.80.70.1-0.40.6-0.1-0.00.10.00.10.10.50.2
Bone: cortical porosity0.10.10.50.40.5-0.2-0.10.30.3-0.4-0.1-0.3-0.1-0.10.7-0.1
Bone: cortical thickness0.10.10.3-0.3-0.2-0.50.2-0.30.3-0.4-0.3-0.3-0.3-0.30.40.1
Bone: cortical thickness0.30.30.8-0.20.20.6-0.10.5-0.40.30.80.70.70.8-0.9-0.2
Bone: cortical tissue density0.10.21.1-0.2-0.20.6-0.20.5-0.50.40.40.40.40.4-1.00.3
Condit. Reinf. active minus inactive responses0.80.91.40.91.11.2-0.81.0-0.90.81.11.11.11.1-1.00.4
Condit. Reinf. active-inactive response ratio1.41.52.21.31.31.5-1.11.2-1.11.21.31.41.31.3-1.30.3
Condit. Reinf. active responses0.00.00.10.10.3-0.00.1-0.00.2-0.20.20.20.20.20.2-0.1
Condit. Reinf. inactive responses2.83.75.0-1.9-1.8-2.21.9-2.02.0-2.1-1.9-1.9-1.9-1.92.1-1.1
Incentive salience index mean0.10.20.7-0.3-0.2-0.20.5-0.40.5-0.5-0.3-0.3-0.3-0.30.4-0.8
Condit. Reinf. lever presses1.32.02.4-1.1-1.2-1.41.5-1.51.5-1.4-1.4-1.4-1.4-1.41.5-1.5
Condit. Reinf. active minus inactive responses0.10.10.30.50.30.3-0.40.4-0.30.30.20.10.20.2-0.20.5
Condit. Reinf. active-inactive response ratio0.10.21.80.60.4-0.2-0.50.3-0.20.20.20.10.20.20.41.3
Condit. Reinf. active responses0.10.20.30.60.60.5-0.40.1-0.30.30.40.40.40.4-0.20.1
Condit. Reinf. inactive responses0.50.71.40.71.01.2-0.60.5-0.70.80.90.90.90.9-1.0-0.4
Condit. Reinf. lever presses0.60.91.21.10.91.0-1.00.9-1.01.01.00.90.91.0-0.90.5
Condit. Reinf. lever reinforcers received0.40.51.11.01.00.8-0.80.5-0.70.70.80.70.70.8-0.40.5
Conditioned reinforcement - actives0.00.10.3-0.2-0.20.00.2-0.20.2-0.1-0.2-0.1-0.3-0.30.0-0.6
Conditioned reinforcement - inactives0.10.40.80.70.90.7-0.60.4-0.50.60.70.70.70.6-0.5-0.2
Conditioned locomotion0.00.00.2-0.3-0.3-0.00.3-0.20.2-0.2-0.2-0.0-0.2-0.1-0.1-0.4
Patch foraging indifference point 0 sec0.71.93.11.31.51.8-1.21.2-1.31.31.41.61.51.4-1.50.3
Patch foraging indifference point AUC0.92.22.7-1.6-1.6-1.41.4-1.41.4-1.5-1.6-1.6-1.7-1.61.2-1.0
Delay disc. indifference point, 0s delay1.11.32.0-0.7-0.7-1.11.0-1.31.3-1.1-1.1-1.3-1.2-1.11.4-1.0
Delay disc. indifference point, 16s delay0.71.01.31.10.90.9-1.11.1-1.11.10.90.90.90.9-0.81.0
Delay disc. indifference point, 2s delay0.70.71.70.90.80.5-0.90.7-0.80.91.00.80.81.0-0.41.3
Delay disc. indifference point, 24s delay0.00.00.10.30.20.1-0.10.0-0.10.1-0.0-0.1-0.1-0.00.1-0.0
Delay disc. indifference point, 4s delay0.10.10.5-0.0-0.10.6-0.10.2-0.30.30.30.20.10.3-0.7-0.2
Delay disc. indifference point, 8s delay0.71.22.31.51.31.3-1.21.1-1.11.21.11.01.01.1-0.80.7
Indifference point function ln k0.92.83.91.51.61.6-1.51.6-1.61.62.01.92.02.0-1.51.2
Indifference point function log k0.92.83.91.51.61.6-1.51.6-1.61.62.01.92.02.0-1.51.2
Patch foraging total patch changes 0 sec0.82.53.91.51.82.0-1.41.4-1.51.51.71.81.71.7-1.60.4
Patch foraging total patch changes 12 sec0.60.92.5-1.2-0.9-0.21.1-1.10.9-1.0-0.8-0.7-0.8-0.80.1-1.6
Patch foraging total patch changes 18 sec1.02.34.2-2.0-1.6-1.01.7-1.61.4-1.6-1.5-1.3-1.4-1.50.6-2.0
Patch foraging total patch changes 24 sec0.20.62.7-0.8-0.4-0.10.8-0.90.7-0.7-0.8-0.7-0.7-0.80.2-1.7
Patch foraging total patch changes 6 sec0.10.10.5-0.30.00.10.3-0.20.2-0.4-0.3-0.1-0.2-0.3-0.0-0.7
Patch foraging time to switch 0 sec0.00.00.10.10.3-0.0-0.00.10.1-0.1-0.3-0.0-0.2-0.30.1-0.3
Patch foraging water rate 0 sec0.00.10.2-0.3-0.4-0.40.3-0.50.3-0.3-0.1-0.3-0.2-0.10.40.1
Patch foraging water rate 12 sec0.20.61.0-0.6-1.0-1.00.8-1.00.7-0.6-0.8-0.8-0.8-0.80.7-0.4
Patch foraging water rate 18 sec1.32.85.9-1.0-1.2-2.31.5-2.11.8-1.6-1.6-1.7-1.6-1.62.4-0.7
Patch foraging water rate 24 sec0.00.00.1-0.2-0.1-0.30.2-0.30.2-0.1-0.1-0.0-0.1-0.10.30.1
Patch foraging water rate 6 sec2.94.36.2-2.4-2.3-2.02.3-2.52.1-2.0-1.8-2.0-1.9-1.81.5-1.9
Seeking ratio, delayed vs. immediate footshock4.46.37.02.52.52.6-2.52.5-2.52.52.62.62.62.6-2.42.1
Distance traveled before self-admin1.53.44.22.02.01.4-2.01.8-1.81.82.01.82.02.0-1.12.0
Distance traveled after self-admin0.20.31.50.60.5-0.5-0.50.2-0.10.20.30.10.20.30.71.2
Extensor digitorum longus weight0.20.61.9-0.3-0.4-1.40.3-0.60.6-0.7-0.9-0.7-0.7-0.91.20.9
Bone: elastic displacement0.10.10.7-0.5-0.8-0.10.20.00.1-0.3-0.3-0.5-0.3-0.3-0.1-0.0
Bone: elastic work0.00.10.3-0.2-0.6-0.30.1-0.00.2-0.2-0.2-0.3-0.1-0.20.20.2
Bone: endosteal estimation0.00.10.20.30.10.4-0.20.2-0.20.40.20.20.20.2-0.3-0.2
Bone: endosteal perimeter0.20.51.00.60.31.0-0.50.6-0.70.90.60.70.70.6-1.0-0.5
Epididymis fat weight0.21.01.91.41.31.1-1.00.9-0.81.01.11.01.01.1-0.50.6
Delta time in closed arm before/after self-admin0.50.50.70.60.70.7-0.70.6-0.70.70.80.80.80.8-0.70.6
Delta time in open arm before/after self-admin0.81.01.2-1.1-1.1-0.91.0-0.90.9-0.9-1.1-1.0-1.1-1.10.6-0.9
Diff in mean of infusions in LGA sessions0.10.31.4-0.6-0.60.60.30.2-0.20.1-0.1-0.00.2-0.1-1.2-0.9
Delay discount exponential model param0.30.40.6-0.8-0.6-0.80.7-0.70.7-0.8-0.7-0.5-0.6-0.70.6-0.5
Extinction: sum of active levers before priming2.94.55.02.12.02.1-2.12.2-2.22.22.12.12.12.1-2.02.0
Active lever presses in extinction session 60.10.10.2-0.10.0-0.1-0.10.1-0.10.10.30.30.40.3-0.00.5
Bone: final force1.21.94.7-0.9-0.7-1.81.3-1.41.6-1.6-1.2-1.4-1.2-1.22.2-0.7
Bone: final moment0.71.23.4-0.6-0.4-1.40.9-1.11.3-1.3-0.9-1.1-0.9-0.91.8-0.5
Food consumed during 24 hour testing period3.77.59.3-3.0-2.8-2.43.0-3.02.9-2.9-2.5-2.5-2.5-2.52.2-3.0
Glucose0.10.20.6-0.20.0-0.40.4-0.50.6-0.4-0.3-0.3-0.3-0.30.8-0.8
Heart weight1.32.23.71.20.91.8-1.31.5-1.61.71.51.41.51.5-1.90.6
Delay discount hyperbolic model param0.30.40.6-0.7-0.6-0.80.7-0.60.7-0.8-0.7-0.6-0.6-0.70.6-0.4
Intermittent access intake day 1-15 change1.16.27.7-2.4-2.1-2.52.6-2.72.7-2.6-2.5-2.3-2.5-2.42.2-2.8
Intermittent access intake escalation0.94.75.8-2.1-1.8-2.22.3-2.42.3-2.2-2.2-1.9-2.1-2.12.0-2.4
Intermittent access intake escalation 21.93.25.6-1.7-1.5-1.62.0-2.01.9-1.9-1.8-1.6-1.8-1.71.3-2.4
Intermitt. access day 1 inactive lever presses0.00.10.20.10.40.4-0.10.2-0.20.20.30.20.30.3-0.4-0.3
Intermitt. access day 15 inactive lever presses0.21.12.10.91.01.3-0.91.0-1.11.01.11.11.11.0-1.50.4
Intermitt. access escalation Index0.10.30.50.60.50.5-0.50.5-0.60.60.60.60.70.6-0.70.5
Intermittent access day 1 total infusions0.61.82.61.51.31.3-1.61.6-1.51.61.11.31.10.9-1.11.5
Intermittent access day 15 total infusions0.00.00.10.00.1-0.2-0.10.0-0.00.1-0.20.1-0.1-0.30.10.1
Intermittent access terminal intake (last 3 days)0.00.10.20.30.20.3-0.30.3-0.30.30.10.40.10.0-0.40.0
Intermittent access total infusions0.00.00.10.10.00.0-0.20.1-0.10.1-0.20.0-0.1-0.30.00.0
Intermittent access day 1 locomotion0.00.10.50.2-0.0-0.1-0.40.3-0.20.3-0.10.0-0.0-0.10.20.7
Intermittent access day 15 total locomotion0.00.10.50.40.4-0.2-0.40.2-0.20.2-0.00.3-0.0-0.10.50.7
Intermittent access total locomotion0.10.10.30.40.2-0.2-0.30.1-0.00.1-0.10.1-0.1-0.10.60.5
Intermittent access standard deviation0.31.62.3-1.2-1.1-1.01.3-1.31.3-1.3-1.4-1.1-1.4-1.31.0-1.5
Left kidney weight0.64.76.1-1.9-2.0-2.42.0-2.22.3-2.3-2.3-2.3-2.3-2.32.5-1.4
Right kidney weight0.10.92.3-0.3-0.3-1.00.7-0.91.1-1.1-1.0-1.0-1.0-1.01.5-0.8
Cocaine induced anxiety0.51.22.50.91.01.6-0.81.0-1.01.01.21.31.21.2-1.5-0.0
Post-drug Anxiety0.60.71.50.70.71.1-0.60.8-0.80.80.80.90.80.8-1.20.2
Baseline Anxiety0.30.61.3-0.6-0.7-1.10.5-0.60.6-0.6-0.9-0.8-0.9-0.90.90.1
Tail length0.63.54.4-1.9-1.9-2.02.0-2.12.0-1.9-1.7-1.7-1.7-1.71.8-1.8
Length with tail0.20.92.1-0.3-0.6-1.10.7-0.81.1-0.9-1.0-1.1-1.0-1.01.5-0.8
Length without tail0.10.41.41.21.00.4-0.80.7-0.40.40.40.30.40.40.20.5
Times rat made contact with spout0.10.10.3-0.3-0.1-0.40.2-0.50.3-0.3-0.0-0.0-0.0-0.00.50.1
Lifetime Intake0.00.00.20.0-0.10.10.0-0.00.10.0-0.3-0.0-0.2-0.50.0-0.3
Liver weight, left0.10.10.60.10.2-0.10.3-0.20.4-0.3-0.1-0.2-0.1-0.10.4-0.8
Liver weight, right0.10.21.00.60.6-0.3-0.1-0.20.3-0.3-0.1-0.2-0.1-0.21.00.2
Locomotor activity0.30.50.90.90.90.4-0.80.7-0.60.70.70.60.60.7-0.20.7
Locomotor testing distance0.20.40.60.70.70.6-0.70.8-0.70.70.70.70.50.7-0.60.4
Locomotor testing rearing0.10.52.5-0.6-0.4-0.20.8-0.70.7-0.7-0.6-0.6-0.6-0.60.1-1.6
Locomotion in novel chamber0.40.61.51.21.20.8-0.90.6-0.60.60.70.70.60.7-0.20.4
Locomotion in novel chamber post-restriction0.30.91.4-0.6-0.8-1.20.8-0.90.9-0.8-1.1-1.0-1.1-1.01.2-0.6
Fecal boli incidents, locomotor time 10.51.42.4-1.1-1.4-0.91.2-0.91.0-1.1-1.3-1.3-1.3-1.30.6-1.6
Change in fecal boli incidents, locomotor task0.10.10.3-0.20.20.50.00.0-0.20.10.50.50.50.4-0.5-0.2
Time >=10cm from walls, locomotor time 10.20.21.10.10.1-0.70.1-0.30.4-0.4-0.6-0.4-0.5-0.51.00.1
Bouts of movement, locomotor time 10.70.92.3-1.5-1.3-0.71.1-1.00.8-0.9-0.7-0.8-0.7-0.70.2-1.0
Total resting periods, locomotor time 10.40.51.7-1.3-1.2-0.50.8-0.60.5-0.6-0.5-0.5-0.5-0.5-0.2-0.8
Rest time, locomotor task time 10.40.61.5-1.2-1.1-0.90.9-0.90.7-0.8-0.8-0.6-0.6-0.80.3-0.4
Distance moved, locomotor task time 10.20.71.00.80.81.0-0.81.0-0.80.80.80.80.70.8-0.80.7
Vertical activity count, locomotor time 10.10.50.8-0.3-0.4-0.60.6-0.60.8-0.8-0.7-0.8-0.7-0.70.9-0.7
Time >=10cm from walls, locomotor time 20.20.41.50.91.00.1-0.70.3-0.40.40.60.60.60.60.31.2
Bouts of movement, locomotor time 20.00.10.3-0.1-0.10.2-0.10.2-0.30.30.40.40.40.4-0.60.3
Total resting periods, locomotor time 20.00.10.4-0.5-0.40.20.1-0.0-0.20.10.20.10.10.2-0.6-0.1
Rest time, locomotor task time 20.40.62.4-1.5-1.5-0.30.8-0.30.2-0.3-0.4-0.6-0.5-0.5-0.8-0.7
Distance moved, locomotor task time 21.72.25.32.02.31.2-1.71.3-1.21.21.41.51.51.4-0.21.7
Vertical activity count, locomotor time 20.10.31.50.50.6-0.30.2-0.50.6-0.6-0.4-0.3-0.3-0.41.2-0.5
Light reinforcement 15.826.329.0-5.1-5.1-4.95.3-5.45.3-5.3-5.1-5.1-5.1-5.14.6-5.1
Light reinforcement 26.514.717.6-3.9-4.2-3.74.0-4.03.8-3.8-3.9-3.9-3.9-3.93.2-3.5
Bone: marrow area0.00.10.20.40.20.5-0.20.2-0.30.50.30.30.30.3-0.4-0.2
Bone: maximum diameter0.30.51.01.00.80.8-0.80.7-0.70.90.60.70.70.6-0.60.1
Bone: maximum force0.20.30.7-0.6-0.4-0.70.6-0.40.7-0.7-0.4-0.5-0.3-0.40.8-0.3
Bone: maximum moment0.00.10.3-0.3-0.1-0.40.3-0.20.4-0.4-0.2-0.3-0.1-0.20.6-0.2
Mean time between licks in bursts0.10.31.11.10.80.6-0.70.7-0.50.60.20.20.10.2-0.3-0.1
Mean num. licks in bursts0.10.31.10.30.50.2-0.50.3-0.50.50.70.70.70.7-0.31.1
Cd content in liver1.41.53.70.70.41.7-0.91.2-1.31.31.41.21.21.4-1.90.5
Co content in liver1.21.42.11.41.11.4-1.31.4-1.31.31.11.01.01.1-1.20.8
Cu content in liver0.10.10.30.30.4-0.2-0.1-0.20.2-0.3-0.00.1-0.1-0.00.60.3
Fe content in liver2.12.67.1-1.1-0.8-2.51.2-1.71.7-1.8-1.5-1.4-1.4-1.52.70.0
K content in liver0.70.72.11.21.10.2-1.00.9-0.60.40.60.60.60.60.21.5
Mg content in liver0.60.71.31.11.20.5-1.00.9-0.70.50.80.80.80.8-0.21.1
Mn content in liver0.70.82.10.30.31.1-0.71.1-1.00.80.80.80.80.8-1.40.7
Na content in liver0.20.21.30.40.3-0.8-0.1-0.20.3-0.3-0.3-0.2-0.3-0.31.20.6
Rb content in liver0.60.61.4-0.8-0.2-1.00.8-0.81.0-1.2-0.6-0.6-0.6-0.61.1-0.6
Se content in liver2.12.55.9-1.0-1.0-2.21.3-1.61.7-1.8-1.5-1.6-1.5-1.52.4-0.3
Sr content in liver0.30.30.80.90.80.5-0.60.5-0.50.60.40.40.40.4-0.20.4
Zn content in liver2.52.93.91.51.71.7-1.61.4-1.61.62.01.91.92.0-1.41.6
Bone: minimum diameter1.12.02.3-1.3-1.4-1.51.4-1.51.4-1.4-1.5-1.5-1.5-1.51.4-1.1
Time in familiar zone, hab. session 10.70.81.4-0.5-0.6-0.80.8-1.21.0-0.8-1.0-1.0-1.0-1.01.0-0.9
Time in novel zone, hab. session 10.50.61.70.30.30.3-0.71.0-0.80.70.70.70.70.7-0.71.3
Total zone transitions, hab. session 10.20.30.50.50.60.7-0.50.6-0.50.60.40.40.40.4-0.60.1
Total locomotion distance, hab. session 10.40.61.30.40.50.9-0.60.9-0.80.80.70.70.70.7-1.10.5
Locomotion velocity, hab. session 10.40.61.20.50.50.9-0.60.8-0.80.80.80.80.80.8-1.10.4
Time in familiar zone, hab. session 21.31.52.8-1.3-1.5-0.71.4-1.41.1-1.0-1.2-1.2-1.2-1.20.4-1.7
Time in novel zone, hab. session 22.83.05.31.51.81.2-1.92.0-1.81.61.71.81.71.7-1.32.3
Total zone transitions, hab. session 20.10.10.3-0.10.30.40.10.1-0.0-0.00.20.30.20.2-0.3-0.6
Total locomotion distance, hab. session 20.10.10.4-0.10.20.4-0.10.2-0.30.20.40.40.40.4-0.6-0.0
Locomotion velocity, hab. session 20.00.00.1-0.3-0.00.10.2-0.10.0-0.10.10.20.10.1-0.2-0.2
Novel to familiar place preference ratio1.01.32.20.91.00.9-1.11.5-1.21.11.21.21.21.2-1.01.3
Novelty place preference0.71.01.70.70.80.8-0.91.3-1.00.91.01.01.01.0-0.91.1
Time in novel zone, NPP test0.81.01.70.90.90.6-1.01.3-1.01.01.11.01.11.1-0.61.3
Total zone transitions, NPP test0.00.00.30.30.50.3-0.10.00.0-0.00.10.10.10.10.0-0.3
Total locomotion distance, NPP test0.10.20.40.40.60.3-0.40.2-0.30.30.50.50.50.5-0.20.5
Locomotion velocity, NPP test0.00.00.10.00.30.2-0.0-0.1-0.0-0.00.20.20.20.2-0.10.1
Intraocular pressure3.96.48.92.22.02.8-2.42.4-2.72.82.52.42.62.6-3.02.0
Delta distance traveled before/after self-admin2.83.14.1-1.5-1.6-2.01.6-1.71.8-1.8-1.9-1.8-2.0-1.92.0-1.0
Delta ambulatory time before/after self-admin2.95.06.3-2.0-2.0-2.42.1-2.12.3-2.3-2.4-2.3-2.5-2.42.4-1.6
Parametrial fat weight0.00.10.90.10.00.50.10.00.1-0.0-0.2-0.2-0.1-0.1-0.2-0.9
Pavlov. Cond. lever latency0.00.00.2-0.1-0.30.3-0.00.0-0.10.1-0.1-0.2-0.1-0.1-0.4-0.4
Pavlov. Cond. magazine entry latency0.00.00.20.20.2-0.2-0.10.2-0.10.10.00.10.00.00.10.5
Pavlov. Cond. change in total contacts0.70.71.8-0.6-0.4-1.30.8-1.01.0-0.9-0.7-0.6-0.7-0.71.3-0.3
Pavlov. Cond. index score0.10.20.50.50.60.0-0.40.5-0.30.30.30.40.30.30.10.7
Pavlov. Cond. latency score0.10.10.20.30.40.1-0.20.4-0.20.20.20.30.20.2-0.10.4
Pavlov. Cond. lever contacts0.10.10.30.40.6-0.2-0.20.2-0.00.10.30.40.30.30.30.6
Pavlov. Cond. magazine entry number0.20.30.8-0.8-0.90.20.5-0.30.2-0.3-0.2-0.5-0.2-0.2-0.5-0.9
Pavlov. Cond. intertrial magazine entries0.10.10.20.30.30.4-0.30.2-0.30.20.40.30.40.4-0.30.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.70.80.1-0.50.6-0.40.40.40.50.40.4-0.00.8
Pavlov. Cond. response bias0.20.31.00.60.8-0.5-0.40.1-0.00.10.20.40.20.20.71.0
Pavlov. Cond. lever latency0.20.30.8-0.1-0.00.4-0.40.7-0.50.40.60.50.70.6-0.70.9
Pavlov. Cond. magazine entry latency0.10.10.50.40.30.00.1-0.30.2-0.1-0.3-0.2-0.3-0.30.3-0.7
Pavlov. Cond. change in total contacts0.00.10.50.70.7-0.0-0.2-0.30.1-0.0-0.00.0-0.0-0.00.6-0.2
Pavlov. Cond. index score0.10.10.30.60.6-0.1-0.1-0.30.2-0.1-0.2-0.1-0.2-0.20.5-0.4
Pavlov. Cond. latency score0.10.10.30.40.4-0.20.0-0.40.3-0.2-0.3-0.2-0.3-0.30.5-0.4
Pavlov. Cond. lever contacts0.40.61.3-0.1-0.2-0.60.6-1.00.8-0.7-0.9-0.8-0.9-0.91.0-1.2
Pavlov. Cond. magazine entry number0.00.10.3-0.6-0.5-0.10.20.10.0-0.10.1-0.10.00.1-0.20.3
Pavlov. Cond. intertrial magazine entries0.40.91.8-1.3-1.2-0.81.1-0.90.9-1.1-0.7-0.9-0.8-0.70.5-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.60.6-0.0-0.1-0.30.2-0.0-0.2-0.0-0.2-0.20.5-0.4
Pavlov. Cond. response bias0.20.20.60.50.5-0.20.1-0.50.4-0.2-0.4-0.3-0.4-0.40.8-0.8
Time in closed arm before self-admin2.23.95.3-1.6-1.7-2.21.8-2.02.1-2.0-2.0-2.2-2.0-2.02.3-1.6
Time in closed arm after self-admin1.11.21.7-1.0-1.1-1.31.1-1.21.2-1.2-1.0-1.2-1.0-1.01.3-0.8
Time in open arm before self-admin1.61.92.61.41.51.6-1.41.4-1.41.31.41.41.41.4-1.30.9
Time in open arm after self-admin0.91.01.41.11.21.0-1.11.0-1.01.00.91.00.90.9-0.81.0
Bone: periosteal estimation0.00.10.3-0.2-0.4-0.20.3-0.30.3-0.2-0.4-0.3-0.3-0.40.2-0.6
Bone: periosteal perimeter0.20.30.60.50.30.8-0.40.5-0.60.70.60.50.70.6-0.8-0.3
Bone: post-yield work0.30.40.90.10.30.8-0.30.5-0.60.70.90.80.90.9-0.9-0.3
Progressive ratio test 1 active lever presses0.00.10.40.10.1-0.3-0.20.00.10.1-0.3-0.1-0.2-0.40.60.2
Progressive ratio test 1 breakpoint0.00.10.40.20.1-0.3-0.20.00.10.1-0.2-0.1-0.2-0.30.70.3
Progressive ratio test 1 inactive lever presses0.00.10.20.40.50.2-0.40.3-0.20.30.20.30.20.00.10.1
Progressive ratio test 2 active lever presses0.00.00.10.10.0-0.1-0.20.2-0.00.1-0.2-0.0-0.2-0.30.20.2
Progressive ratio test 2 breakpoint0.00.00.10.10.10.0-0.30.3-0.20.2-0.10.1-0.1-0.20.10.3
Progressive ratio test 2 inactive lever presses0.51.42.01.11.21.4-1.21.2-1.21.31.21.31.21.0-1.30.9
Incentive Sensitization - Responses0.00.00.1-0.2-0.10.20.00.1-0.1-0.0-0.10.0-0.1-0.2-0.3-0.2
Incentive Sensitization - Breakpoint0.00.00.1-0.3-0.20.20.10.10.0-0.1-0.2-0.0-0.1-0.2-0.3-0.3
Sum of active levers in priming session hrs 5-60.30.30.70.00.20.6-0.30.4-0.50.40.70.60.80.7-0.80.1
Progressive ratio0.10.41.3-1.0-1.1-0.40.7-0.70.4-0.4-0.5-0.5-0.4-0.5-0.1-0.2
Food seeking constrained by brief footshock1.92.33.4-1.8-1.7-1.31.8-1.81.6-1.6-1.2-1.4-1.2-1.21.0-1.8
Seeking ratio, punishment vs. effort0.51.02.1-0.5-0.3-1.00.9-1.01.2-1.2-0.9-0.9-0.9-0.91.5-1.3
Retroperitoneal fat weight0.21.02.60.80.71.6-0.71.1-0.90.90.90.80.90.9-1.5-0.2
Reaction time number correct0.41.31.91.01.21.0-1.11.0-1.11.01.31.31.41.2-0.91.2
Reaction time mean minus median0.31.83.71.51.90.8-1.51.1-1.11.11.51.41.21.5-0.31.7
Reaction time mean minus median AUC0.21.52.71.41.60.8-1.41.1-1.21.11.31.21.11.3-0.51.6
Reaction time num false alarms4.16.99.32.93.03.0-2.62.6-2.62.62.62.62.72.6-2.41.6
Reaction time num false alarms AUC2.76.38.32.72.92.9-2.52.4-2.52.52.52.62.72.5-2.31.5
Reaction time trials correct on left0.41.31.91.01.21.0-1.11.0-1.11.01.31.31.41.2-0.91.2
Reaction time trials on left0.41.52.11.11.31.1-1.21.1-1.21.11.31.31.51.3-0.91.3
Reaction time mean1.43.25.62.12.21.4-2.11.7-1.71.71.71.61.61.7-0.82.4
Reaction time mean AUC1.43.35.32.12.21.4-2.11.7-1.81.81.71.71.61.7-0.92.3
Median of all reaction times1.62.64.71.91.81.3-1.91.6-1.61.61.41.41.41.4-0.82.2
Reaction time omissions1.93.25.32.32.21.8-2.11.9-1.81.91.51.61.61.5-1.11.7
Reaction time false alarm rate1.62.33.51.81.71.9-1.51.5-1.51.61.41.41.41.4-1.50.6
Reaction time premature initiation rate3.45.29.9-2.4-2.4-1.52.5-2.32.3-2.2-2.3-2.3-2.3-2.31.3-3.1
Reaction time premature initiations0.72.04.6-1.6-1.5-0.81.6-1.41.4-1.4-1.3-1.4-1.3-1.30.6-2.1
Std. dev. reaction times0.62.03.91.72.01.0-1.61.2-1.31.31.51.41.31.5-0.41.7
Reaction time trials completed0.41.52.11.11.31.1-1.21.1-1.21.11.31.31.51.3-0.91.3
Reaction time trials AUC0.51.62.21.11.41.2-1.21.1-1.21.11.41.41.51.4-1.01.4
Run reversals in cocaine runway, females0.40.40.90.90.90.3-0.70.6-0.50.60.60.70.60.7-0.20.8
Run reversals in cocaine runway, males0.10.20.50.20.20.0-0.40.6-0.40.20.40.30.30.5-0.20.7
Latency to leave start box in cocaine runway0.20.30.70.30.30.7-0.50.5-0.60.60.70.70.60.5-0.90.2
Latency to leave start box in cocaine runway, F0.60.81.50.60.70.6-0.90.9-1.00.90.91.00.90.9-0.91.2
Latency to leave start box in cocaine runway, M0.40.42.7-0.5-0.50.30.7-0.60.4-0.4-0.3-0.3-0.3-0.4-0.2-1.7
Std. dev. time between licks in bursts0.30.50.9-0.4-0.5-0.70.5-0.40.6-0.7-0.9-0.9-0.9-0.90.6-0.6
Total sessions with >9 infusions0.00.00.00.1-0.0-0.1-0.10.1-0.00.2-0.1-0.0-0.1-0.20.20.1
Short access day 1 total inactive lever presses0.10.10.5-0.10.0-0.50.1-0.20.3-0.2-0.4-0.2-0.4-0.50.7-0.1
Short access day 10 total inactive lever presses0.00.30.7-0.4-0.3-0.40.6-0.60.7-0.6-0.6-0.6-0.6-0.60.5-0.8
Short access day 1 total infusions0.40.71.00.90.90.9-1.00.9-0.91.00.70.90.80.6-0.60.8
Short access day 10 total infusions0.00.10.3-0.3-0.3-0.00.1-0.00.1-0.1-0.3-0.2-0.3-0.5-0.1-0.3
Short access total infusions0.00.00.10.20.20.2-0.20.2-0.20.3-0.00.20.0-0.2-0.1-0.0
Short access day 1 locomotion1.52.53.41.41.61.5-1.61.6-1.61.61.61.81.61.6-1.41.5
Short access day 10 total locomotion0.00.10.10.30.20.3-0.30.3-0.30.40.20.30.20.3-0.20.3
Short access total locomotion0.30.50.70.60.60.8-0.70.7-0.80.80.70.80.70.7-0.70.6
One hour access (0.3 mA shock)0.40.51.90.30.31.1-0.30.5-0.70.60.50.70.50.4-1.4-0.3
Compulsive drug intake0.20.21.4-0.1-0.10.40.10.1-0.40.20.50.30.50.6-1.2-0.3
One hour access (shock baseline)0.10.20.60.30.30.7-0.30.4-0.50.50.30.50.30.1-0.70.1
Social response proportion0.10.10.30.2-0.0-0.4-0.10.10.2-0.2-0.4-0.4-0.4-0.40.50.5
Social responses0.10.10.40.40.20.7-0.20.4-0.30.30.10.10.10.1-0.6-0.5
Social time1.21.92.8-1.5-1.6-1.41.3-1.11.2-1.3-1.7-1.5-1.6-1.71.0-0.7
Soleus weight0.00.10.50.1-0.30.5-0.20.6-0.30.4-0.20.1-0.1-0.2-0.7-0.5
Bone: stiffness0.00.10.50.10.5-0.50.1-0.10.3-0.20.0-0.00.10.00.7-0.0
Tibialis anterior weight0.51.62.41.31.40.9-1.31.1-1.21.21.31.31.41.3-0.71.5
Time to tail flick, vehicle, before self-admin0.10.10.9-0.5-0.60.30.20.1-0.20.20.10.1-0.10.1-0.9-0.2
Time to tail flick, vehicle, after self-admin0.40.72.0-1.3-1.4-0.31.0-0.70.6-0.7-0.7-0.9-0.6-0.7-0.3-1.2
Time to tail flick, test, before self-admin1.01.21.70.90.91.2-1.01.0-1.21.21.11.11.11.1-1.30.9
Time to tail flick, test, after self-admin0.70.71.2-0.9-0.9-1.10.8-1.00.8-0.8-0.6-0.8-0.8-0.60.9-0.3
Delta time to tail flick, vehicle, before/after SA0.30.30.6-0.6-0.6-0.40.6-0.60.5-0.6-0.6-0.6-0.3-0.60.3-0.7
Delta time to tail flick, test, before/after SA1.21.43.9-0.7-0.8-1.70.9-1.21.3-1.2-1.1-1.2-1.3-1.12.0-0.1
Tibia length0.30.82.41.51.5-0.1-0.90.4-0.40.60.70.60.70.70.91.2
Ambulatory time before self-admin1.34.04.72.22.11.6-2.22.0-2.02.02.12.02.12.1-1.42.1
Ambulatory time after self-admin0.20.41.5-0.2-0.2-1.10.3-0.40.6-0.6-0.5-0.6-0.5-0.51.20.4
Bone: tissue strength0.20.20.4-0.1-0.3-0.50.2-0.00.4-0.4-0.6-0.6-0.5-0.60.60.2
Total heroin consumption0.20.20.50.50.50.7-0.40.4-0.50.50.50.40.70.5-0.60.0
Bone: trabecular number1.42.67.3-2.7-2.2-1.81.9-1.31.5-1.8-1.3-1.3-1.3-1.30.8-0.8
Bone: trabecular spacing0.71.02.71.61.21.1-1.31.0-1.01.00.70.70.70.7-0.60.9
Bone: trabecular thickness2.53.55.8-2.4-1.9-2.32.0-1.92.0-2.1-1.6-1.7-1.6-1.61.9-0.8
Bone: trabecular tissue density0.61.02.11.01.40.9-0.90.6-0.80.81.21.21.21.2-0.50.9
Water consumed over 24 hours1.73.33.6-1.8-1.8-1.81.9-1.91.9-1.8-1.9-1.9-1.8-1.91.7-1.7
Number of responses in last shaping day1.72.23.31.31.41.8-1.31.4-1.51.41.61.61.61.6-1.70.9