Hub : Genes

Snx20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Snx20 0.16 0.08 0.0e+00 0.16 0.05 0.17 -0 6.0e-18 2.7e-06 4.5e-19 5.0e-01
2 Liver gene expression Snx20 0.07 0.04 2.8e-09 0.07 0.03 0.07 0.04 3.4e-08 2.4e-04 4.5e-08 4.0e-05
3 Brain mRNA stability Snx20 0.11 0.06 1.1e-15 0.16 0.17 0.17 0.17 4.1e-15 1.3e-15 9.7e-16 1.3e-15
4 NAcc mRNA stability Snx20 0.03 0.02 2.2e-03 0 0.01 0.01 0.01 1.9e-01 1.8e-02 1.7e-02 1.5e-02
5 LHb gene expression Snx20 0.3 0.14 6.9e-06 0.18 0.09 0.11 -0.01 5.0e-05 3.1e-03 1.6e-03 6.2e-01
6 BLA gene expression Snx20 0.05 0.03 4.6e-03 0.04 0.03 0.01 0.04 2.6e-03 7.3e-03 8.8e-02 5.8e-03
7 BLA mRNA stability Snx20 0.08 0.05 6.5e-05 0.07 0.07 0.06 0.07 1.8e-04 2.0e-04 2.7e-04 1.8e-04
8 Brain gene expression Snx20 0.17 0.08 0.0e+00 0.22 0.23 0.23 0.23 8.9e-20 7.4e-21 8.6e-21 7.0e-21
9 NAcc gene expression Snx20 0.06 0.04 4.1e-07 0.05 0.04 0.04 0.04 2.8e-06 8.1e-06 2.1e-05 7.5e-06
10 Adipose gene expression Snx20 0.06 0.05 2.8e-06 0.05 -0 0.05 -0 1.2e-06 8.4e-01 3.0e-06 4.5e-01
11 PL mRNA stability Snx20 0.02 0.01 7.9e-03 0.02 0.02 0.02 0.02 2.6e-03 4.7e-03 5.6e-03 3.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.42.44.7-1.8-2.2-1.81.5-1.6-1.6-1.21.3-1.3-1.1-1.2
Area under the delay curve0.50.51.20.71.10.7-1.10.70.70.6-0.70.60.60.6
BMI with tail1.85.97.22.42.52.7-1.92.52.42.4-2.52.52.42.4
BMI without tail0.10.20.50.00.30.30.20.50.30.6-0.50.70.60.6
Body weight0.72.85.31.52.32.0-0.81.71.71.6-1.71.61.61.6
Weight adjusted by age3.74.25.71.92.32.4-0.92.02.12.1-2.22.12.12.1
Bone surface0.40.71.4-1.1-1.1-0.91.2-0.9-0.8-0.50.6-0.6-0.4-0.4
Bone volume1.52.64.0-2.0-1.7-1.72.0-1.7-1.6-1.31.4-1.4-1.2-1.3
Breakpoint value in progressive ratio session0.50.50.8-0.6-0.8-0.80.2-0.8-0.7-0.60.8-0.9-0.8-0.6
Number of licking bursts0.40.50.7-0.6-0.5-0.70.4-0.7-0.7-0.80.8-0.9-0.8-0.8
Context. condit. distance diff. score4.45.311.22.91.62.0-3.32.32.32.1-1.92.22.12.1
Locomotion velocity, session 10.20.20.5-0.5-0.2-0.70.6-0.4-0.5-0.20.5-0.2-0.3-0.3
Locomotion distance, session 10.10.10.40.3-0.6-0.2-0.6-0.1-0.10.00.10.10.10.1
Locomotion velocity, session 20.00.10.20.2-0.2-0.3-0.40.30.10.2-0.10.10.20.2
Locomotion distance, session 20.20.20.80.70.30.3-0.90.40.30.5-0.40.40.50.5
Locomotion velocity, session 32.22.53.01.61.71.7-1.11.61.71.5-1.71.61.61.6
Locomotion distance, session 30.40.51.20.81.10.8-0.70.60.70.5-0.60.60.60.6
Stereotopy head waving bouts, day 31.11.41.71.11.11.0-0.91.21.21.3-1.21.21.31.3
Stereotopy head waving duration, day 31.72.02.61.41.01.2-1.21.41.41.6-1.51.51.61.6
Locomotion velocity, session 71.31.43.71.50.10.8-1.91.11.11.1-1.01.21.11.1
Locomotion distance, session 70.30.31.00.0-1.0-0.6-0.7-0.4-0.4-0.50.5-0.5-0.5-0.5
Stereotopy head waving bouts, day 71.21.31.91.01.41.2-0.61.21.11.3-1.11.21.21.2
Stereotopy head waving duration, day 70.10.10.5-0.10.60.30.7-0.0-0.10.3-0.10.10.30.3
Locomotion velocity, session 81.41.65.01.80.10.8-2.21.11.11.2-0.91.11.21.2
Locomotion distance, session 81.82.78.12.30.81.2-2.81.41.51.4-1.21.51.41.4
Degree of sensitization distance0.30.31.5-0.3-1.2-0.8-0.4-0.4-0.4-0.40.5-0.5-0.4-0.4
Degree of sensitization stereotypy1.21.32.10.91.41.3-0.31.11.01.3-1.11.21.21.2
Conditioned locomotion0.20.20.3-0.6-0.3-0.30.5-0.6-0.5-0.50.4-0.5-0.5-0.5
Cocaine response after cond. corrected1.31.53.01.50.61.1-1.71.11.31.1-1.11.11.11.1
Cocaine response after cond. not corrected0.91.01.61.20.61.1-1.31.01.11.0-1.00.91.01.0
Cocaine response before conditioning1.11.32.5-1.4-0.6-0.91.6-1.1-1.2-1.11.1-1.1-1.1-1.1
Saline control response1.11.53.0-0.8-1.6-1.70.1-1.5-1.4-0.91.4-1.0-0.9-0.9
Bone: connectivity density1.42.26.6-1.6-2.6-1.81.1-1.5-1.4-1.11.3-1.2-1.1-1.1
Bone: cortical apparent density0.10.20.70.5-0.40.1-0.80.30.30.4-0.30.40.40.4
Bone: cortical area0.00.10.1-0.3-0.2-0.20.3-0.2-0.3-0.20.2-0.2-0.2-0.2
Bone: cortical porosity0.00.00.10.10.20.3-0.1-0.0-0.1-0.00.10.0-0.00.0
Bone: cortical porosity0.00.00.1-0.10.20.20.3-0.3-0.3-0.10.2-0.2-0.1-0.1
Bone: cortical thickness0.00.00.1-0.2-0.20.00.2-0.1-0.1-0.00.0-0.0-0.00.0
Bone: cortical thickness0.40.41.40.4-1.20.2-0.60.50.30.7-0.40.80.70.8
Bone: cortical tissue density0.20.20.80.5-0.40.1-0.90.40.30.4-0.30.50.40.4
Condit. Reinf. active minus inactive responses1.01.11.71.21.00.9-1.31.00.81.1-0.91.01.01.0
Condit. Reinf. active-inactive response ratio1.71.93.41.71.31.2-1.81.41.21.3-1.11.41.31.3
Condit. Reinf. active responses0.00.00.1-0.00.1-0.10.2-0.0-0.20.20.0-0.00.20.2
Condit. Reinf. inactive responses3.74.46.6-2.4-2.2-2.02.6-2.1-2.1-1.91.8-2.1-1.8-1.8
Incentive salience index mean0.10.10.3-0.2-0.1-0.5-0.0-0.4-0.6-0.30.5-0.4-0.3-0.3
Condit. Reinf. lever presses1.52.02.5-1.4-1.1-1.51.2-1.4-1.4-1.51.5-1.6-1.5-1.5
Condit. Reinf. active minus inactive responses0.10.10.30.30.60.40.10.20.20.1-0.20.00.10.1
Condit. Reinf. active-inactive response ratio0.10.11.0-0.30.30.41.00.10.00.1-0.20.00.10.1
Condit. Reinf. active responses0.10.10.20.50.50.3-0.10.40.20.4-0.30.30.40.4
Condit. Reinf. inactive responses0.70.81.81.20.80.5-1.40.80.80.8-0.70.90.80.8
Condit. Reinf. lever presses0.70.91.51.01.20.9-0.60.91.00.9-0.90.90.90.9
Condit. Reinf. lever reinforcers received0.30.40.70.70.80.7-0.20.70.60.6-0.60.60.60.6
Conditioned reinforcement - actives1.01.01.31.21.01.0-1.11.01.11.1-1.00.90.90.9
Conditioned reinforcement - inactives1.92.23.61.91.11.2-1.61.51.31.6-1.31.51.51.6
Conditioned locomotion0.10.10.40.40.20.2-0.70.30.30.5-0.30.30.40.4
Patch foraging indifference point 0 sec1.42.23.91.71.61.1-2.01.51.31.5-1.11.51.41.5
Patch foraging indifference point AUC2.02.32.6-1.4-1.5-1.51.2-1.6-1.6-1.61.6-1.6-1.6-1.6
Delay disc. indifference point, 0s delay1.11.21.5-1.1-0.9-1.10.8-1.2-1.2-1.21.2-1.2-1.1-1.2
Delay disc. indifference point, 16s delay0.90.92.00.81.41.0-0.91.00.90.8-1.00.80.80.8
Delay disc. indifference point, 2s delay0.80.91.10.61.00.9-0.90.90.90.9-1.00.91.10.9
Delay disc. indifference point, 24s delay0.00.00.30.20.60.1-0.20.20.10.0-0.10.10.00.0
Delay disc. indifference point, 4s delay0.30.32.60.5-0.00.0-1.60.20.20.1-0.20.10.20.1
Delay disc. indifference point, 8s delay1.31.43.01.31.71.2-1.21.11.11.0-1.01.01.01.0
Indifference point function ln k2.23.14.11.71.11.6-1.41.81.72.0-1.81.92.02.0
Indifference point function log k2.23.14.11.71.11.6-1.41.81.72.0-1.81.92.02.0
Patch foraging total patch changes 0 sec1.72.84.51.91.71.2-2.11.71.51.7-1.31.71.61.7
Patch foraging total patch changes 12 sec0.40.61.1-0.2-0.9-1.0-0.5-0.8-1.0-0.71.0-0.6-0.7-0.6
Patch foraging total patch changes 18 sec1.82.33.4-1.2-1.9-1.90.6-1.6-1.7-1.41.7-1.4-1.5-1.4
Patch foraging total patch changes 24 sec0.30.40.8-0.0-0.5-0.7-0.5-0.6-0.6-0.70.9-0.6-0.7-0.7
Patch foraging total patch changes 6 sec0.00.10.2-0.00.1-0.4-0.2-0.2-0.4-0.20.5-0.2-0.3-0.2
Patch foraging time to switch 0 sec0.00.10.30.20.60.1-0.3-0.00.0-0.20.1-0.1-0.2-0.1
Patch foraging water rate 0 sec0.10.20.8-0.6-0.7-0.40.9-0.5-0.5-0.20.3-0.3-0.2-0.3
Patch foraging water rate 12 sec0.40.61.0-1.0-0.8-0.91.0-0.6-0.7-0.70.6-0.7-0.7-0.7
Patch foraging water rate 18 sec2.12.86.8-2.2-1.0-1.52.6-1.6-1.6-1.51.3-1.6-1.5-1.5
Patch foraging water rate 24 sec0.10.10.4-0.4-0.2-0.20.6-0.2-0.3-0.00.10.0-0.1-0.1
Patch foraging water rate 6 sec3.04.45.7-2.3-2.4-2.41.9-2.1-2.1-2.02.0-2.0-2.0-2.1
Seeking ratio, delayed vs. immediate footshock5.15.96.72.62.22.4-2.22.62.42.5-2.42.52.42.5
Distance traveled before self-admin1.01.12.00.71.41.20.11.01.01.0-1.11.01.11.0
Distance traveled after self-admin0.40.53.5-0.90.0-0.11.9-0.4-0.3-0.40.2-0.3-0.3-0.4
Extensor digitorum longus weight0.20.73.2-1.3-0.2-0.21.8-0.7-0.6-0.70.4-0.8-0.8-0.7
Bone: elastic displacement0.00.00.20.10.00.1-0.5-0.1-0.1-0.20.1-0.3-0.2-0.2
Bone: elastic work0.00.00.0-0.10.10.10.0-0.1-0.1-0.10.0-0.20.0-0.1
Bone: endosteal estimation0.10.20.40.60.60.4-0.60.50.50.4-0.40.40.40.4
Bone: endosteal perimeter0.40.81.91.10.90.6-1.41.00.90.8-0.70.80.80.8
Epididymis fat weight0.10.30.60.60.80.4-0.80.50.50.3-0.40.40.40.4
Delta time in closed arm before/after self-admin1.51.51.81.11.21.2-0.61.31.21.3-1.31.31.31.3
Delta time in open arm before/after self-admin2.62.53.2-1.4-1.8-1.70.4-1.5-1.6-1.71.7-1.6-1.7-1.7
Diff in mean of infusions in LGA sessions0.10.10.70.4-0.4-0.1-0.80.00.10.00.1-0.2-0.20.0
Delay discount exponential model param0.60.61.6-0.7-1.0-0.61.3-0.7-0.7-0.60.7-0.6-0.7-0.6
Extinction: sum of active levers before priming3.43.44.61.91.71.8-2.11.81.91.7-1.91.71.81.7
Active lever presses in extinction session 60.00.00.1-0.3-0.4-0.2-0.0-0.2-0.20.10.1-0.10.00.1
Bone: final force1.22.04.5-1.7-0.7-1.12.1-1.5-1.6-1.21.3-1.3-1.2-1.1
Bone: final moment0.71.13.1-1.3-0.3-0.81.8-1.2-1.2-0.81.0-1.0-0.9-0.8
Food consumed during 24 hour testing period6.07.29.4-2.6-2.7-3.12.0-2.8-2.9-2.62.9-2.6-2.6-2.6
Glucose0.10.20.4-0.4-0.7-0.30.6-0.4-0.5-0.30.4-0.3-0.3-0.3
Heart weight2.84.05.61.92.42.0-1.52.12.02.0-2.02.02.02.0
Delay discount hyperbolic model param0.60.61.6-0.8-1.0-0.71.3-0.7-0.7-0.70.7-0.7-0.7-0.7
Intermittent access intake day 1-15 change3.83.75.0-1.7-2.2-2.02.0-1.8-1.9-1.82.0-1.8-1.9-1.9
Intermittent access intake escalation5.75.67.1-2.2-2.7-2.52.4-2.3-2.4-2.22.4-2.2-2.3-2.4
Intermittent access intake escalation 23.13.14.8-1.3-2.2-2.01.6-1.6-1.8-1.71.9-1.6-1.7-1.8
Intermitt. access day 1 inactive lever presses0.30.40.50.70.50.4-0.70.50.40.6-0.60.60.70.7
Intermitt. access day 15 inactive lever presses0.80.91.71.30.30.7-1.20.90.71.1-0.80.91.01.0
Intermitt. access escalation Index0.30.30.4-0.2-0.6-0.6-0.6-0.4-0.5-0.50.5-0.5-0.5-0.5
Intermittent access day 1 total infusions3.13.64.61.91.92.2-1.71.92.01.9-2.01.81.81.8
Intermittent access day 15 total infusions0.00.00.10.0-0.20.00.3-0.00.10.10.0-0.0-0.1-0.1
Intermittent access terminal intake (last 3 days)0.20.20.50.70.20.4-0.40.50.50.6-0.40.40.30.3
Intermittent access total infusions0.20.20.30.60.40.5-0.30.40.50.5-0.40.30.30.3
Intermittent access day 1 locomotion0.70.71.60.51.31.0-0.50.80.91.0-0.90.70.80.9
Intermittent access day 15 total locomotion0.20.20.5-0.00.70.60.30.40.50.6-0.60.40.40.3
Intermittent access total locomotion0.30.30.80.20.90.80.30.50.60.7-0.60.50.50.5
Intermittent access standard deviation0.20.20.4-0.3-0.6-0.50.6-0.4-0.5-0.30.5-0.3-0.5-0.5
Left kidney weight0.20.61.5-0.80.2-0.31.2-0.8-0.7-0.80.6-0.8-0.7-0.8
Right kidney weight0.10.42.40.51.60.80.10.40.40.4-0.50.40.50.4
Cocaine induced anxiety2.02.35.82.20.61.0-2.41.51.21.5-1.11.51.41.4
Post-drug Anxiety0.91.02.21.30.40.7-1.51.00.81.1-0.81.00.90.9
Baseline Anxiety1.11.13.8-1.6-0.2-0.61.9-1.0-0.7-1.00.7-1.0-1.0-1.0
Tail length1.64.96.3-2.5-1.7-2.32.2-2.2-2.3-2.22.3-2.1-2.2-2.2
Length with tail0.10.30.6-0.50.4-0.30.7-0.4-0.4-0.60.5-0.6-0.5-0.6
Length without tail1.53.45.91.92.42.2-1.41.71.91.7-1.81.61.71.7
Times rat made contact with spout0.10.21.0-0.5-0.3-0.31.0-0.2-0.4-0.00.1-0.0-0.0-0.0
Lifetime Intake0.20.20.40.60.40.5-0.60.40.50.6-0.30.30.30.3
Liver weight, left0.10.10.80.6-0.00.1-0.90.10.10.3-0.10.20.30.3
Liver weight, right0.00.00.30.20.30.1-0.50.0-0.10.00.0-0.20.00.0
Locomotor activity0.30.51.20.41.10.9-0.00.60.60.6-0.70.70.70.6
Locomotor testing distance0.20.40.60.50.80.7-0.50.70.60.6-0.60.70.60.6
Locomotor testing rearing0.30.50.8-0.3-0.8-0.9-0.1-0.8-0.8-0.70.9-0.7-0.8-0.7
Locomotion in novel chamber0.50.61.60.81.30.9-0.10.70.60.6-0.70.70.70.6
Locomotion in novel chamber post-restriction0.10.20.4-0.60.0-0.30.3-0.4-0.3-0.50.3-0.6-0.4-0.5
Fecal boli incidents, locomotor time 11.21.31.7-0.8-1.2-1.20.5-1.1-1.0-1.31.3-1.3-1.3-1.3
Change in fecal boli incidents, locomotor task0.10.10.40.3-0.3-0.1-0.6-0.10.00.20.00.10.20.2
Time >=10cm from walls, locomotor time 10.20.20.7-0.60.4-0.10.9-0.4-0.4-0.50.4-0.4-0.4-0.5
Bouts of movement, locomotor time 11.01.01.4-0.9-1.1-1.20.7-1.2-1.1-1.01.0-1.0-1.0-1.0
Total resting periods, locomotor time 10.50.50.9-0.6-0.9-0.90.5-0.8-0.7-0.70.7-0.7-0.8-0.7
Rest time, locomotor task time 10.70.71.4-0.9-1.1-0.91.2-0.6-0.7-0.70.8-0.7-0.8-0.7
Distance moved, locomotor task time 10.91.03.81.00.90.9-1.90.80.80.8-0.90.90.80.8
Vertical activity count, locomotor time 10.30.40.6-0.6-0.3-0.60.2-0.8-0.7-0.70.6-0.7-0.6-0.7
Time >=10cm from walls, locomotor time 20.40.41.30.21.10.60.60.40.50.6-0.60.50.70.6
Bouts of movement, locomotor time 20.10.20.50.20.10.2-0.70.40.30.4-0.40.40.50.4
Total resting periods, locomotor time 20.10.10.50.1-0.3-0.1-0.70.20.10.1-0.20.10.20.1
Rest time, locomotor task time 20.30.41.7-0.3-1.3-0.8-0.1-0.4-0.5-0.50.6-0.5-0.4-0.5
Distance moved, locomotor task time 21.61.94.91.22.21.7-0.91.21.11.3-1.31.31.21.3
Vertical activity count, locomotor time 20.10.10.5-0.10.7-0.00.7-0.5-0.3-0.20.3-0.3-0.3-0.2
Light reinforcement 114.626.729.9-5.1-4.9-5.54.0-5.3-5.5-5.35.4-5.2-5.3-5.2
Light reinforcement 211.114.917.5-4.0-3.7-4.23.0-3.8-3.9-4.04.0-4.0-4.0-3.9
Bone: marrow area0.10.30.50.60.70.4-0.60.60.60.5-0.50.50.50.5
Bone: maximum diameter0.50.91.11.00.91.0-1.01.01.00.9-0.91.00.90.9
Bone: maximum force0.20.31.0-0.8-0.4-0.41.0-0.6-0.7-0.30.4-0.4-0.2-0.3
Bone: maximum moment0.10.10.5-0.4-0.1-0.20.7-0.4-0.4-0.10.2-0.20.0-0.0
Mean time between licks in bursts0.30.51.11.01.00.8-1.10.70.70.3-0.40.30.30.3
Mean num. licks in bursts0.20.30.50.10.00.40.40.40.30.7-0.60.70.70.7
Cd content in liver0.30.31.80.90.20.2-1.30.30.30.4-0.20.50.40.4
Co content in liver0.00.00.30.10.10.50.30.00.00.1-0.20.10.10.1
Cu content in liver0.10.10.40.20.70.3-0.10.30.10.3-0.20.40.20.3
Fe content in liver1.01.24.7-1.6-0.7-0.62.2-0.9-1.0-0.80.6-0.8-0.8-0.8
K content in liver0.20.21.00.11.00.60.40.20.10.2-0.30.20.20.2
Mg content in liver0.90.91.40.81.21.1-0.30.80.71.0-0.91.01.01.0
Mn content in liver0.70.81.10.90.91.1-0.91.00.90.9-1.00.80.90.9
Na content in liver0.20.20.8-0.40.90.10.9-0.1-0.0-0.1-0.1-0.1-0.2-0.1
Rb content in liver0.70.92.8-1.2-0.6-0.71.7-1.0-1.2-0.60.8-0.7-0.6-0.6
Se content in liver2.02.56.2-2.0-1.0-1.42.5-1.4-1.7-1.31.4-1.4-1.3-1.3
Sr content in liver0.00.00.1-0.10.20.00.2-0.2-0.2-0.30.2-0.3-0.3-0.3
Zn content in liver3.33.64.52.11.01.8-2.11.91.82.0-1.82.02.02.0
Bone: minimum diameter0.91.72.1-1.5-0.7-1.31.4-1.4-1.3-1.41.3-1.4-1.4-1.4
Time in familiar zone, hab. session 10.70.71.0-0.70.0-0.80.6-0.8-0.8-1.00.9-0.9-1.0-1.0
Time in novel zone, hab. session 10.40.40.70.3-0.00.80.10.70.70.7-0.80.60.70.7
Total zone transitions, hab. session 10.20.30.40.6-0.10.5-0.60.60.60.4-0.50.50.50.5
Total locomotion distance, hab. session 10.40.60.90.90.20.6-0.90.80.90.8-0.80.90.80.8
Locomotion velocity, hab. session 10.50.61.00.90.20.6-1.00.80.80.8-0.80.90.80.8
Time in familiar zone, hab. session 21.11.21.9-0.7-1.0-1.40.0-1.0-1.1-1.21.3-1.2-1.2-1.2
Time in novel zone, hab. session 22.62.63.51.31.11.9-0.61.61.71.7-1.91.81.81.8
Total zone transitions, hab. session 20.10.10.50.3-0.7-0.1-0.40.00.00.3-0.00.40.30.3
Total locomotion distance, hab. session 20.10.20.50.4-0.70.1-0.40.20.30.4-0.30.50.40.4
Locomotion velocity, hab. session 20.00.10.60.0-0.7-0.2-0.1-0.1-0.00.2-0.00.20.20.2
Novel to familiar place preference ratio1.31.32.20.91.51.2-0.61.01.11.2-1.21.21.31.3
Novelty place preference0.91.01.50.81.21.0-0.40.91.01.1-1.01.11.11.1
Time in novel zone, NPP test1.01.01.80.61.41.0-0.10.91.01.1-1.11.11.11.1
Total zone transitions, NPP test0.00.00.10.3-0.40.2-0.3-0.00.00.1-0.00.20.10.1
Total locomotion distance, NPP test0.10.20.30.30.10.5-0.10.30.40.5-0.50.50.60.6
Locomotion velocity, NPP test0.00.00.10.2-0.30.1-0.2-0.00.10.2-0.10.20.20.2
Intraocular pressure5.37.48.72.92.42.5-2.92.82.92.7-2.72.62.72.7
Delta distance traveled before/after self-admin1.41.62.3-1.3-1.1-1.11.5-1.2-1.2-1.31.2-1.2-1.3-1.3
Delta ambulatory time before/after self-admin2.32.53.0-1.6-1.4-1.51.7-1.6-1.6-1.61.6-1.5-1.6-1.6
Parametrial fat weight0.00.10.30.50.20.3-0.60.00.1-0.10.0-0.1-0.10.1
Pavlov. Cond. lever latency0.00.00.20.3-0.0-0.0-0.4-0.10.0-0.10.1-0.1-0.1-0.1
Pavlov. Cond. magazine entry latency0.00.00.1-0.10.00.40.20.20.30.1-0.30.20.10.1
Pavlov. Cond. change in total contacts0.70.82.4-1.2-0.9-0.91.5-0.7-0.8-0.60.6-0.6-0.6-0.6
Pavlov. Cond. index score0.10.10.20.10.40.40.00.40.30.3-0.40.40.30.3
Pavlov. Cond. latency score0.10.10.10.10.10.3-0.20.30.30.3-0.30.30.30.3
Pavlov. Cond. lever contacts0.10.10.2-0.20.40.20.40.30.20.4-0.30.40.30.3
Pavlov. Cond. magazine entry number0.10.10.40.2-0.4-0.4-0.6-0.2-0.2-0.20.3-0.3-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.30.50.50.3-0.40.30.20.4-0.30.20.40.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.40.30.50.6-0.10.60.50.5-0.60.60.50.5
Pavlov. Cond. response bias0.20.30.7-0.20.70.50.90.40.30.5-0.60.60.50.5
Pavlov. Cond. lever latency0.10.20.30.2-0.30.3-0.40.30.30.6-0.40.40.60.6
Pavlov. Cond. magazine entry latency0.00.00.00.2-0.0-0.0-0.1-0.00.0-0.20.1-0.1-0.2-0.2
Pavlov. Cond. change in total contacts0.00.00.3-0.10.20.00.5-0.2-0.2-0.10.1-0.1-0.1-0.1
Pavlov. Cond. index score0.00.00.20.10.50.00.3-0.1-0.0-0.20.1-0.0-0.2-0.2
Pavlov. Cond. latency score0.00.00.1-0.00.2-0.00.4-0.1-0.1-0.30.1-0.2-0.3-0.3
Pavlov. Cond. lever contacts0.50.60.8-0.6-0.1-0.80.8-0.8-0.8-0.90.9-0.8-0.9-0.9
Pavlov. Cond. magazine entry number0.00.00.1-0.3-0.1-0.3-0.0-0.2-0.3-0.10.2-0.2-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.50.71.0-0.8-0.6-1.00.5-0.9-1.0-0.80.9-0.8-0.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.00.00.20.10.40.10.3-0.1-0.0-0.10.1-0.0-0.1-0.1
Pavlov. Cond. response bias0.10.10.2-0.10.5-0.20.5-0.2-0.3-0.40.3-0.2-0.4-0.4
Time in closed arm before self-admin3.53.94.8-2.2-1.6-1.92.0-2.0-2.0-2.02.0-2.0-2.1-2.0
Time in closed arm after self-admin0.70.72.2-1.2-0.6-0.71.5-0.8-0.8-0.60.7-0.7-0.6-0.6
Time in open arm before self-admin3.13.44.12.01.91.9-1.31.91.81.8-1.91.81.91.8
Time in open arm after self-admin0.60.71.01.00.90.8-1.00.90.80.7-0.80.80.80.7
Bone: periosteal estimation0.00.00.00.10.1-0.0-0.10.10.1-0.00.0-0.00.00.0
Bone: periosteal perimeter0.40.71.31.00.80.6-1.20.70.80.8-0.70.70.80.8
Bone: post-yield work0.30.40.80.50.20.0-0.40.60.60.8-0.50.70.90.8
Progressive ratio test 1 active lever presses1.51.52.80.91.71.4-0.41.21.31.4-1.31.21.21.2
Progressive ratio test 1 breakpoint0.91.01.90.71.41.2-0.21.01.01.1-1.10.90.90.9
Progressive ratio test 1 inactive lever presses0.20.20.30.40.60.5-0.20.40.40.5-0.50.40.40.4
Progressive ratio test 2 active lever presses0.30.30.50.50.40.7-0.10.60.60.7-0.60.50.50.5
Progressive ratio test 2 breakpoint0.40.40.70.70.50.8-0.30.70.70.8-0.70.60.60.6
Progressive ratio test 2 inactive lever presses2.83.24.12.01.51.8-1.71.81.82.0-1.81.81.81.8
Incentive Sensitization - Responses0.00.00.40.2-0.6-0.1-0.0-0.1-0.2-0.00.1-0.1-0.1-0.1
Incentive Sensitization - Breakpoint0.10.10.50.1-0.7-0.20.0-0.2-0.2-0.10.2-0.2-0.2-0.2
Sum of active levers in priming session hrs 5-60.10.10.50.1-0.5-0.3-0.7-0.2-0.2-0.00.2-0.1-0.0-0.0
Progressive ratio0.10.21.2-0.2-1.1-0.6-0.1-0.2-0.3-0.10.2-0.1-0.2-0.1
Food seeking constrained by brief footshock1.82.23.8-1.4-1.8-1.90.3-1.6-1.7-1.31.6-1.3-1.3-1.3
Seeking ratio, punishment vs. effort0.60.81.1-1.0-0.3-0.80.8-1.0-1.1-0.91.0-1.0-0.9-0.9
Retroperitoneal fat weight0.51.73.61.81.61.2-1.91.01.11.0-1.01.01.11.0
Reaction time number correct0.91.32.01.00.71.2-1.01.11.01.4-1.21.31.41.3
Reaction time mean minus median1.11.52.80.81.71.3-0.11.31.01.2-1.31.51.31.3
Reaction time mean minus median AUC1.01.32.20.91.51.3-0.31.31.11.1-1.21.31.11.2
Reaction time num false alarms5.27.09.03.02.32.7-2.82.72.72.6-2.62.62.62.6
Reaction time num false alarms AUC4.76.58.22.92.12.6-2.72.52.52.5-2.52.52.62.6
Reaction time trials correct on left0.91.32.01.00.71.2-1.01.11.01.4-1.21.31.41.3
Reaction time trials on left1.11.62.21.10.81.3-1.01.21.11.5-1.31.41.41.4
Reaction time mean1.92.64.61.42.21.9-0.51.71.61.5-1.71.61.51.6
Reaction time mean AUC2.02.74.51.42.11.9-0.61.81.71.5-1.81.71.61.6
Median of all reaction times1.62.23.51.31.91.8-0.61.61.51.3-1.61.41.31.4
Reaction time omissions1.92.54.51.72.11.8-1.11.61.71.4-1.61.51.31.4
Reaction time false alarm rate1.72.33.61.91.41.5-1.81.61.61.3-1.41.41.41.4
Reaction time premature initiation rate3.85.16.6-1.5-2.3-2.51.2-2.5-2.3-2.42.6-2.4-2.4-2.4
Reaction time premature initiations1.31.82.6-0.8-1.6-1.50.5-1.6-1.5-1.31.6-1.4-1.3-1.3
Std. dev. reaction times1.21.73.31.01.81.4-0.21.41.21.3-1.31.51.31.3
Reaction time trials completed1.11.62.21.10.81.3-1.01.21.11.5-1.31.41.41.4
Reaction time trials AUC1.11.62.31.10.91.3-1.01.21.11.5-1.31.41.41.4
Run reversals in cocaine runway, females1.21.21.50.91.21.1-0.61.11.11.1-1.21.21.21.1
Run reversals in cocaine runway, males0.10.10.1-0.1-0.40.3-0.00.10.10.2-0.40.20.40.2
Latency to leave start box in cocaine runway0.20.21.40.40.30.2-1.20.30.40.4-0.30.40.30.4
Latency to leave start box in cocaine runway, F0.50.60.80.30.60.7-0.60.90.80.8-0.90.90.80.8
Latency to leave start box in cocaine runway, M1.31.32.1-0.4-1.0-1.4-0.7-1.3-1.2-1.11.4-1.1-1.2-1.1
Std. dev. time between licks in bursts0.50.61.0-0.5-0.8-0.60.2-0.8-0.8-1.00.8-1.0-1.0-1.0
Total sessions with >9 infusions0.70.81.30.91.10.9-1.00.80.90.9-0.80.80.80.9
Short access day 1 total inactive lever presses0.20.20.4-0.3-0.6-0.50.3-0.6-0.6-0.30.5-0.5-0.5-0.5
Short access day 10 total inactive lever presses0.40.50.8-0.2-0.9-0.8-0.1-0.7-0.8-0.80.8-0.7-0.7-0.7
Short access day 1 total infusions2.12.32.81.51.61.5-1.51.41.51.7-1.41.51.41.5
Short access day 10 total infusions0.10.10.50.50.00.4-0.70.20.30.4-0.30.20.20.2
Short access total infusions0.10.10.20.30.30.3-0.30.20.30.4-0.20.20.20.2
Short access day 1 locomotion2.42.53.21.51.71.5-1.41.51.51.8-1.61.71.61.7
Short access day 10 total locomotion0.30.40.70.60.80.6-0.40.50.70.7-0.60.50.50.5
Short access total locomotion1.11.11.50.91.11.1-0.81.01.11.2-1.11.01.11.1
One hour access (0.3 mA shock)0.10.10.60.8-0.30.0-0.50.20.20.3-0.10.20.10.1
Compulsive drug intake1.01.01.6-0.9-1.3-1.21.0-1.0-1.0-0.91.0-0.9-0.9-0.8
One hour access (shock baseline)1.01.11.91.40.81.0-1.21.01.11.1-1.01.00.90.9
Social response proportion0.00.10.1-0.30.30.20.4-0.1-0.1-0.20.0-0.2-0.2-0.2
Social responses0.20.31.60.80.30.3-1.30.30.40.2-0.30.20.20.2
Social time1.52.02.6-1.5-1.6-1.30.9-1.4-1.3-1.51.3-1.5-1.5-1.5
Soleus weight0.00.10.70.5-0.10.2-0.80.30.4-0.1-0.0-0.1-0.1-0.1
Bone: stiffness0.10.21.3-0.6-0.1-0.21.1-0.3-0.4-0.00.2-0.1-0.0-0.0
Tibialis anterior weight0.62.02.81.11.61.7-0.51.41.31.6-1.51.31.51.5
Time to tail flick, vehicle, before self-admin0.20.21.10.0-0.9-0.5-1.0-0.1-0.0-0.20.2-0.1-0.2-0.2
Time to tail flick, vehicle, after self-admin0.80.81.6-0.5-1.3-1.1-0.0-0.9-0.9-0.91.0-1.0-1.0-0.9
Time to tail flick, test, before self-admin0.60.50.90.80.60.6-1.00.80.70.8-0.60.80.70.8
Time to tail flick, test, after self-admin0.30.30.5-0.7-0.7-0.70.4-0.6-0.6-0.60.5-0.6-0.4-0.6
Delta time to tail flick, vehicle, before/after SA0.40.40.6-0.4-0.5-0.60.5-0.7-0.7-0.70.8-0.7-0.7-0.7
Delta time to tail flick, test, before/after SA0.80.72.3-1.2-0.4-0.51.5-0.8-0.7-0.80.5-0.8-0.6-0.8
Tibia length0.30.84.2-0.02.10.71.10.50.50.6-0.70.50.70.6
Ambulatory time before self-admin1.31.42.60.91.61.4-0.31.21.21.2-1.31.11.21.2
Ambulatory time after self-admin1.11.24.3-1.4-0.7-0.72.1-1.0-1.0-0.90.9-1.0-0.9-0.9
Bone: tissue strength0.50.50.7-0.70.3-0.30.8-0.8-0.7-0.80.6-0.8-0.8-0.7
Total heroin consumption0.00.10.10.30.30.2-0.00.20.20.3-0.10.10.20.3
Bone: trabecular number1.52.45.1-1.8-2.3-1.71.5-1.6-1.6-1.21.3-1.2-1.1-1.1
Bone: trabecular spacing0.91.22.51.31.61.3-1.31.21.00.8-0.90.80.70.8
Bone: trabecular thickness3.03.66.3-2.4-2.1-1.92.5-2.1-1.9-1.51.5-1.5-1.4-1.5
Bone: trabecular tissue density0.50.81.20.61.00.6-0.30.80.61.1-0.81.11.11.1
Water consumed over 24 hours3.44.04.3-2.0-2.0-2.02.1-1.9-2.0-2.02.0-2.1-2.0-2.0
Number of responses in last shaping day5.65.96.92.62.12.3-2.32.42.42.6-2.42.52.52.5