Hub : Genes

Snx20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Snx20 0.07 0.04 5.6e-09 0.07 0.03 0.06 0.02 5.3e-08 3.1e-04 1.0e-07 1.4e-03
2 pVTA gene expression Snx20 0.06 0.04 1.8e-05 0.04 0.03 0.03 0.04 1.5e-04 2.3e-03 1.9e-03 3.2e-04
3 Adipose mRNA stability Snx20 0.16 0.08 0.0e+00 0.16 0.05 0.18 -0 5.5e-18 2.1e-06 3.9e-19 5.5e-01
4 Brain mRNA stability Snx20 0.11 0.06 1.3e-15 0.16 0.17 0.17 0.17 8.3e-15 6.3e-16 2.3e-15 1.2e-15
5 LHb gene expression Snx20 0.3 0.14 8.2e-06 0.17 0.09 0.1 0.16 6.6e-05 4.8e-03 2.4e-03 1.6e-04
6 BLA mRNA stability Snx20 0.08 0.05 2.3e-04 0.06 0.07 0.04 0.06 4.6e-04 2.0e-04 3.0e-03 4.4e-04
7 PL mRNA stability Snx20 0.02 0.02 5.0e-03 0.02 0.01 0.01 0.01 5.9e-03 1.4e-02 1.5e-02 3.3e-02
8 Brain gene expression Snx20 0.17 0.08 0.0e+00 0.24 0.24 0.24 0.24 4.5e-22 5.3e-22 5.8e-22 5.5e-22
9 NAcc gene expression Snx20 0.06 0.04 4.9e-09 0.05 0.05 0.04 0.05 1.8e-08 3.3e-08 2.6e-06 1.9e-08
10 BLA gene expression Snx20 0.04 0.03 7.5e-03 0.03 0.02 0.01 0.02 1.2e-02 2.0e-02 5.5e-02 4.5e-02
11 Adipose gene expression Snx20 0.06 0.05 2.3e-06 0.06 -0 0.05 -0 7.9e-07 8.3e-01 3.7e-06 4.2e-01
12 NAcc mRNA stability Snx20 0.04 0.02 4.6e-06 0.03 0.03 0.02 0.03 2.7e-05 2.0e-05 2.6e-04 1.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.72.96.62.62.11.82.01.51.61.81.41.41.31.41.0
Area under the delay curve0.40.50.7-0.9-0.7-0.8-0.8-0.7-0.7-0.8-0.7-0.6-0.6-0.7-0.5
BMI with tail2.37.910.6-3.1-3.3-2.4-3.0-2.8-2.8-2.8-2.9-2.7-2.8-2.8-1.9
BMI without tail0.41.11.7-1.1-1.3-0.7-1.0-0.7-0.9-1.0-1.3-1.1-1.2-1.3-0.5
Body weight0.52.04.6-2.2-1.9-1.0-1.7-1.4-1.2-1.4-1.3-1.2-1.3-1.3-0.3
Weight adjusted by age2.53.85.4-2.0-2.1-1.7-2.2-2.3-2.1-1.9-1.9-1.9-1.9-1.8-1.5
Bone surface0.61.12.31.51.11.31.21.11.11.10.70.80.70.70.9
Bone volume2.03.65.22.31.92.22.01.81.91.91.71.71.61.71.7
Breakpoint value in progressive ratio session0.50.61.11.01.10.41.00.70.70.70.80.80.50.80.0
Number of licking bursts0.30.50.70.70.80.60.80.70.80.80.80.80.80.80.6
Context. condit. distance diff. score3.84.67.5-1.9-1.7-2.7-1.9-2.0-2.2-2.3-2.0-2.0-2.0-2.0-2.7
Locomotion velocity, session 10.30.31.2-0.1-0.20.50.51.10.70.40.20.30.20.21.0
Locomotion distance, session 10.00.00.10.1-0.1-0.30.20.00.10.1-0.0-0.1-0.0-0.0-0.2
Locomotion velocity, session 20.00.00.1-0.0-0.0-0.20.10.3-0.0-0.2-0.2-0.2-0.2-0.2-0.3
Locomotion distance, session 20.20.20.6-0.3-0.4-0.8-0.3-0.5-0.4-0.3-0.5-0.5-0.5-0.5-0.7
Locomotion velocity, session 32.42.83.9-1.9-2.0-1.6-1.8-1.6-1.7-1.7-1.6-1.7-1.6-1.6-1.2
Locomotion distance, session 30.40.51.0-1.0-0.9-0.8-0.8-0.7-0.6-0.6-0.5-0.6-0.5-0.5-0.3
Stereotopy head waving bouts, day 31.11.31.9-1.1-1.4-1.1-1.1-0.8-1.1-1.1-1.3-1.2-1.3-1.3-1.0
Stereotopy head waving duration, day 31.51.82.3-1.2-1.4-1.4-1.2-1.0-1.3-1.3-1.5-1.4-1.5-1.5-1.2
Locomotion velocity, session 71.21.33.5-0.4-0.6-1.6-0.8-1.3-1.2-1.1-1.1-1.2-1.1-1.1-1.9
Locomotion distance, session 70.50.62.01.31.4-0.10.80.20.30.50.70.70.70.7-0.7
Stereotopy head waving bouts, day 71.71.94.5-1.9-2.1-0.9-1.5-1.0-1.1-1.2-1.4-1.4-1.4-1.4-0.3
Stereotopy head waving duration, day 70.20.31.3-0.9-1.10.2-0.40.10.1-0.1-0.4-0.3-0.4-0.40.9
Locomotion velocity, session 81.11.33.5-0.6-0.6-1.8-0.7-0.9-1.1-1.1-1.1-1.2-1.1-1.1-1.9
Locomotion distance, session 81.72.45.2-1.2-1.2-2.3-1.1-1.4-1.5-1.5-1.4-1.5-1.4-1.4-2.3
Degree of sensitization distance0.50.62.01.41.40.20.90.40.40.50.50.60.50.5-0.7
Degree of sensitization stereotypy1.41.53.6-1.7-1.9-0.8-1.3-1.0-0.9-1.1-1.3-1.3-1.3-1.3-0.1
Conditioned locomotion0.20.30.50.50.70.60.40.50.40.40.50.60.50.50.4
Cocaine response after cond. corrected1.21.42.8-0.8-0.6-1.5-1.0-1.4-1.3-1.3-1.1-1.1-1.1-1.1-1.7
Cocaine response after cond. not corrected0.81.01.6-0.9-0.7-1.2-0.9-1.3-1.0-1.0-1.0-0.9-0.9-1.0-1.1
Cocaine response before conditioning1.31.64.10.60.31.61.01.21.41.41.21.21.21.22.0
Saline control response1.52.15.72.41.90.72.01.61.41.51.01.10.91.00.1
Bone: connectivity density1.52.47.22.72.31.51.91.21.31.51.11.21.11.10.4
Bone: cortical apparent density0.10.20.80.30.2-0.5-0.1-0.4-0.4-0.3-0.3-0.3-0.3-0.3-0.9
Bone: cortical area0.20.30.40.40.40.60.50.60.60.50.50.50.50.50.6
Bone: cortical porosity0.10.20.6-0.8-0.7-0.1-0.4-0.6-0.10.0-0.1-0.0-0.1-0.10.5
Bone: cortical porosity0.10.10.5-0.4-0.50.2-0.1-0.30.30.40.10.30.10.10.7
Bone: cortical thickness0.10.10.30.30.20.50.20.30.30.40.30.30.30.30.4
Bone: cortical thickness0.30.30.80.2-0.2-0.6-0.1-0.5-0.4-0.3-0.8-0.7-0.7-0.8-0.9
Bone: cortical tissue density0.20.21.10.20.2-0.6-0.2-0.5-0.5-0.4-0.4-0.4-0.4-0.4-1.0
Condit. Reinf. active minus inactive responses0.91.01.4-0.9-1.1-1.2-0.8-1.0-0.9-0.8-1.1-1.1-1.1-1.1-1.0
Condit. Reinf. active-inactive response ratio1.51.62.2-1.3-1.3-1.5-1.1-1.2-1.1-1.2-1.3-1.4-1.3-1.3-1.3
Condit. Reinf. active responses0.00.00.1-0.1-0.30.00.10.00.20.2-0.2-0.2-0.2-0.20.2
Condit. Reinf. inactive responses3.23.95.01.91.82.21.92.02.02.11.91.91.91.92.1
Incentive salience index mean0.10.10.30.30.20.20.50.40.50.50.30.30.30.30.4
Condit. Reinf. lever presses1.42.02.41.11.21.41.51.51.51.41.41.41.41.41.5
Condit. Reinf. active minus inactive responses0.10.10.3-0.5-0.3-0.3-0.4-0.4-0.3-0.3-0.2-0.1-0.2-0.2-0.2
Condit. Reinf. active-inactive response ratio0.10.10.3-0.6-0.40.2-0.5-0.3-0.2-0.2-0.2-0.1-0.2-0.20.4
Condit. Reinf. active responses0.10.20.3-0.6-0.6-0.5-0.4-0.1-0.3-0.3-0.4-0.4-0.4-0.4-0.2
Condit. Reinf. inactive responses0.60.71.4-0.7-1.0-1.2-0.6-0.5-0.7-0.8-0.9-0.9-0.9-0.9-1.0
Condit. Reinf. lever presses0.70.91.2-1.1-0.9-1.0-1.0-0.9-1.0-1.0-1.0-0.9-0.9-1.0-0.9
Condit. Reinf. lever reinforcers received0.40.61.1-1.0-1.0-0.8-0.8-0.5-0.7-0.7-0.8-0.7-0.7-0.8-0.4
Conditioned reinforcement - actives0.00.00.10.20.2-0.00.20.20.20.10.20.10.30.30.0
Conditioned reinforcement - inactives0.30.40.8-0.7-0.9-0.7-0.6-0.4-0.5-0.6-0.7-0.7-0.7-0.6-0.5
Conditioned locomotion0.00.00.10.30.30.00.30.20.20.20.20.00.20.1-0.1
Patch foraging indifference point 0 sec1.12.03.1-1.3-1.5-1.8-1.2-1.2-1.3-1.3-1.4-1.6-1.5-1.4-1.5
Patch foraging indifference point AUC1.62.32.71.61.61.41.41.41.41.51.61.61.71.61.2
Delay disc. indifference point, 0s delay1.21.32.00.70.71.11.01.31.31.11.11.31.21.11.4
Delay disc. indifference point, 16s delay0.91.01.3-1.1-0.9-0.9-1.1-1.1-1.1-1.1-0.9-0.9-0.9-0.9-0.8
Delay disc. indifference point, 2s delay0.60.71.0-0.9-0.8-0.5-0.9-0.7-0.8-0.9-1.0-0.8-0.8-1.0-0.4
Delay disc. indifference point, 24s delay0.00.00.1-0.3-0.2-0.1-0.1-0.0-0.1-0.10.00.10.10.00.1
Delay disc. indifference point, 4s delay0.10.10.50.00.1-0.6-0.1-0.2-0.3-0.3-0.3-0.2-0.1-0.3-0.7
Delay disc. indifference point, 8s delay1.11.32.3-1.5-1.3-1.3-1.2-1.1-1.1-1.2-1.1-1.0-1.0-1.1-0.8
Indifference point function ln k1.72.93.9-1.5-1.6-1.6-1.5-1.6-1.6-1.6-2.0-1.9-2.0-2.0-1.5
Indifference point function log k1.72.93.9-1.5-1.6-1.6-1.5-1.6-1.6-1.6-2.0-1.9-2.0-2.0-1.5
Patch foraging total patch changes 0 sec1.42.73.9-1.5-1.8-2.0-1.4-1.4-1.5-1.5-1.7-1.8-1.7-1.7-1.6
Patch foraging total patch changes 12 sec0.60.71.41.20.90.21.11.10.91.00.80.70.80.80.1
Patch foraging total patch changes 18 sec1.42.24.22.01.61.01.71.61.41.61.51.31.41.50.6
Patch foraging total patch changes 24 sec0.30.40.70.80.40.10.80.90.70.70.80.70.70.80.2
Patch foraging total patch changes 6 sec0.00.10.10.3-0.0-0.10.30.20.20.40.30.10.20.3-0.0
Patch foraging time to switch 0 sec0.00.00.1-0.1-0.30.0-0.0-0.10.10.10.30.00.20.30.1
Patch foraging water rate 0 sec0.00.10.20.30.40.40.30.50.30.30.10.30.20.10.4
Patch foraging water rate 12 sec0.30.71.00.61.01.00.81.00.70.60.80.80.80.80.7
Patch foraging water rate 18 sec2.03.05.91.01.22.31.52.11.81.61.61.71.61.62.4
Patch foraging water rate 24 sec0.00.00.10.20.10.30.20.30.20.10.10.00.10.10.3
Patch foraging water rate 6 sec3.04.36.22.42.32.02.32.52.12.01.82.01.91.81.5
Seeking ratio, delayed vs. immediate footshock5.36.57.0-2.5-2.5-2.6-2.5-2.5-2.5-2.5-2.6-2.6-2.6-2.6-2.4
Distance traveled before self-admin2.53.34.2-2.0-2.0-1.4-2.0-1.8-1.8-1.8-2.0-1.8-2.0-2.0-1.1
Distance traveled after self-admin0.10.20.5-0.6-0.50.5-0.5-0.2-0.1-0.2-0.3-0.1-0.2-0.30.7
Extensor digitorum longus weight0.20.61.90.30.41.40.30.60.60.70.90.70.70.91.2
Bone: elastic displacement0.10.10.70.50.80.10.2-0.00.10.30.30.50.30.3-0.1
Bone: elastic work0.00.10.30.20.60.30.10.00.20.20.20.30.10.20.2
Bone: endosteal estimation0.00.10.2-0.3-0.1-0.4-0.2-0.2-0.2-0.4-0.2-0.2-0.2-0.2-0.3
Bone: endosteal perimeter0.20.51.0-0.6-0.3-1.0-0.5-0.6-0.7-0.9-0.6-0.7-0.7-0.6-1.0
Epididymis fat weight0.31.11.9-1.4-1.3-1.1-1.0-0.9-0.8-1.0-1.1-1.0-1.0-1.1-0.5
Delta time in closed arm before/after self-admin0.60.50.7-0.6-0.7-0.7-0.7-0.6-0.7-0.7-0.8-0.8-0.8-0.8-0.7
Delta time in open arm before/after self-admin1.01.01.21.11.10.91.00.90.90.91.11.01.11.10.6
Diff in mean of infusions in LGA sessions0.20.21.40.60.6-0.60.3-0.2-0.2-0.10.10.0-0.20.1-1.2
Delay discount exponential model param0.40.50.60.80.60.80.70.70.70.80.70.50.60.70.6
Extinction: sum of active levers before priming4.14.55.0-2.1-2.0-2.1-2.1-2.2-2.2-2.2-2.1-2.1-2.1-2.1-2.0
Active lever presses in extinction session 60.00.00.10.1-0.00.1-0.1-0.1-0.1-0.1-0.3-0.3-0.4-0.3-0.0
Bone: final force1.32.04.70.90.71.81.31.41.61.61.21.41.21.22.2
Bone: final moment0.81.23.40.60.41.40.91.11.31.30.91.10.90.91.8
Food consumed during 24 hour testing period5.37.39.33.02.82.43.03.02.92.92.52.52.52.52.2
Glucose0.10.20.60.2-0.00.40.40.50.60.40.30.30.30.30.8
Heart weight1.52.33.7-1.2-0.9-1.8-1.3-1.5-1.6-1.7-1.5-1.4-1.5-1.5-1.9
Delay discount hyperbolic model param0.40.50.60.70.60.80.70.60.70.80.70.60.60.70.6
Intermittent access intake day 1-15 change3.06.17.42.42.12.52.62.72.72.62.52.32.52.42.2
Intermittent access intake escalation2.24.65.72.11.82.22.32.42.32.22.21.92.12.12.0
Intermittent access intake escalation 22.63.04.11.71.51.62.02.01.91.91.81.61.81.71.3
Intermitt. access day 1 inactive lever presses0.00.10.2-0.1-0.4-0.4-0.1-0.2-0.2-0.2-0.3-0.2-0.3-0.3-0.4
Intermitt. access day 15 inactive lever presses0.61.22.1-0.9-1.0-1.3-0.9-1.0-1.1-1.0-1.1-1.1-1.1-1.0-1.5
Intermitt. access escalation Index0.20.30.5-0.6-0.5-0.5-0.5-0.5-0.6-0.6-0.6-0.6-0.7-0.6-0.7
Intermittent access day 1 total infusions1.11.82.6-1.5-1.3-1.3-1.6-1.6-1.5-1.6-1.1-1.3-1.1-0.9-1.1
Intermittent access day 15 total infusions0.00.00.1-0.0-0.10.2-0.1-0.0-0.0-0.10.2-0.10.10.30.1
Intermittent access terminal intake (last 3 days)0.10.10.2-0.3-0.2-0.3-0.3-0.3-0.3-0.3-0.1-0.4-0.1-0.0-0.4
Intermittent access total infusions0.00.00.1-0.1-0.0-0.0-0.2-0.1-0.1-0.10.2-0.00.10.30.0
Intermittent access day 1 locomotion0.00.00.1-0.20.00.1-0.4-0.3-0.2-0.30.1-0.00.00.10.2
Intermittent access day 15 total locomotion0.00.10.2-0.4-0.40.2-0.4-0.2-0.2-0.20.0-0.30.00.10.5
Intermittent access total locomotion0.10.10.3-0.4-0.20.2-0.3-0.1-0.0-0.10.1-0.10.10.10.6
Intermittent access standard deviation0.71.51.91.21.11.01.31.31.31.31.41.11.41.31.0
Left kidney weight1.15.06.11.92.02.42.02.22.32.32.32.32.32.32.5
Right kidney weight0.20.92.30.30.31.00.70.91.11.11.01.01.01.01.5
Cocaine induced anxiety0.91.32.5-0.9-1.0-1.6-0.8-1.0-1.0-1.0-1.2-1.3-1.2-1.2-1.5
Post-drug Anxiety0.70.81.5-0.7-0.7-1.1-0.6-0.8-0.8-0.8-0.8-0.9-0.8-0.8-1.2
Baseline Anxiety0.50.61.30.60.71.10.50.60.60.60.90.80.90.90.9
Tail length0.93.54.41.91.92.02.02.12.01.91.71.71.71.71.8
Length with tail0.20.92.10.30.61.10.70.81.10.91.01.11.01.01.5
Length without tail0.10.41.4-1.2-1.0-0.4-0.8-0.7-0.4-0.4-0.4-0.3-0.4-0.40.2
Times rat made contact with spout0.10.10.30.30.10.40.20.50.30.30.00.00.00.00.5
Lifetime Intake0.00.00.2-0.00.1-0.10.00.00.1-0.00.30.00.20.50.0
Liver weight, left0.00.00.1-0.1-0.20.10.30.20.40.30.10.20.10.10.4
Liver weight, right0.10.21.0-0.6-0.60.3-0.10.20.30.30.10.20.10.21.0
Locomotor activity0.30.50.9-0.9-0.9-0.4-0.8-0.7-0.6-0.7-0.7-0.6-0.6-0.7-0.2
Locomotor testing distance0.30.50.6-0.7-0.7-0.6-0.7-0.8-0.7-0.7-0.7-0.7-0.5-0.7-0.6
Locomotor testing rearing0.20.40.70.60.40.20.80.70.70.70.60.60.60.60.1
Locomotion in novel chamber0.50.61.5-1.2-1.2-0.8-0.9-0.6-0.6-0.6-0.7-0.7-0.6-0.7-0.2
Locomotion in novel chamber post-restriction0.60.91.40.60.81.20.80.90.90.81.11.01.11.01.2
Fecal boli incidents, locomotor time 10.91.32.11.11.40.91.20.91.01.11.31.31.31.30.6
Change in fecal boli incidents, locomotor task0.10.10.30.2-0.2-0.50.0-0.0-0.2-0.1-0.5-0.5-0.5-0.4-0.5
Time >=10cm from walls, locomotor time 10.20.21.1-0.1-0.10.70.10.30.40.40.60.40.50.51.0
Bouts of movement, locomotor time 10.80.92.31.51.30.71.11.00.80.90.70.80.70.70.2
Total resting periods, locomotor time 10.50.51.71.31.20.50.80.60.50.60.50.50.50.5-0.2
Rest time, locomotor task time 10.50.71.51.21.10.90.90.90.70.80.80.60.60.80.3
Distance moved, locomotor task time 10.50.71.0-0.8-0.8-1.0-0.8-1.0-0.8-0.8-0.8-0.8-0.7-0.8-0.8
Vertical activity count, locomotor time 10.20.50.80.30.40.60.60.60.80.80.70.80.70.70.9
Time >=10cm from walls, locomotor time 20.20.30.9-0.9-1.0-0.1-0.7-0.3-0.4-0.4-0.6-0.6-0.6-0.60.3
Bouts of movement, locomotor time 20.10.10.30.10.1-0.2-0.1-0.2-0.3-0.3-0.4-0.4-0.4-0.4-0.6
Total resting periods, locomotor time 20.00.10.40.50.4-0.20.10.0-0.2-0.1-0.2-0.1-0.1-0.2-0.6
Rest time, locomotor task time 20.50.62.41.51.50.30.80.30.20.30.40.60.50.5-0.8
Distance moved, locomotor task time 21.82.25.3-2.0-2.3-1.2-1.7-1.3-1.2-1.2-1.4-1.5-1.5-1.4-0.2
Vertical activity count, locomotor time 20.20.31.5-0.5-0.60.30.20.50.60.60.40.30.30.41.2
Light reinforcement 110.726.429.05.15.14.95.35.45.35.35.15.15.15.14.6
Light reinforcement 29.714.917.63.94.23.74.04.03.83.83.93.93.93.93.2
Bone: marrow area0.10.10.2-0.4-0.2-0.5-0.2-0.2-0.3-0.5-0.3-0.3-0.3-0.3-0.4
Bone: maximum diameter0.30.61.0-1.0-0.8-0.8-0.8-0.7-0.7-0.9-0.6-0.7-0.7-0.6-0.6
Bone: maximum force0.20.30.70.60.40.70.60.40.70.70.40.50.30.40.8
Bone: maximum moment0.10.10.30.30.10.40.30.20.40.40.20.30.10.20.6
Mean time between licks in bursts0.10.31.1-1.1-0.8-0.6-0.7-0.7-0.5-0.6-0.2-0.2-0.1-0.2-0.3
Mean num. licks in bursts0.20.30.5-0.3-0.5-0.2-0.5-0.3-0.5-0.5-0.7-0.7-0.7-0.7-0.3
Cd content in liver1.51.63.7-0.7-0.4-1.7-0.9-1.2-1.3-1.3-1.4-1.2-1.2-1.4-1.9
Co content in liver1.31.52.1-1.4-1.1-1.4-1.3-1.4-1.3-1.3-1.1-1.0-1.0-1.1-1.2
Cu content in liver0.00.10.3-0.3-0.40.2-0.10.20.20.30.0-0.10.10.00.6
Fe content in liver2.32.87.11.10.82.51.21.71.71.81.51.41.41.52.7
K content in liver0.60.51.5-1.2-1.1-0.2-1.0-0.9-0.6-0.4-0.6-0.6-0.6-0.60.2
Mg content in liver0.60.71.3-1.1-1.2-0.5-1.0-0.9-0.7-0.5-0.8-0.8-0.8-0.8-0.2
Mn content in liver0.70.82.1-0.3-0.3-1.1-0.7-1.1-1.0-0.8-0.8-0.8-0.8-0.8-1.4
Na content in liver0.20.21.3-0.4-0.30.8-0.10.20.30.30.30.20.30.31.2
Rb content in liver0.60.71.40.80.21.00.80.81.01.20.60.60.60.61.1
Se content in liver2.32.75.91.01.02.21.31.61.71.81.51.61.51.52.4
Sr content in liver0.30.30.8-0.9-0.8-0.5-0.6-0.5-0.5-0.6-0.4-0.4-0.4-0.4-0.2
Zn content in liver2.62.93.9-1.5-1.7-1.7-1.6-1.4-1.6-1.6-2.0-1.9-1.9-2.0-1.4
Bone: minimum diameter1.12.12.31.31.41.51.41.51.41.41.51.51.51.51.4
Time in familiar zone, hab. session 10.90.81.40.50.60.80.81.21.00.81.01.01.01.01.0
Time in novel zone, hab. session 10.50.51.1-0.3-0.3-0.3-0.7-1.0-0.8-0.7-0.7-0.7-0.7-0.7-0.7
Total zone transitions, hab. session 10.20.30.5-0.5-0.6-0.7-0.5-0.6-0.5-0.6-0.4-0.4-0.4-0.4-0.6
Total locomotion distance, hab. session 10.40.61.3-0.4-0.5-0.9-0.6-0.9-0.8-0.8-0.7-0.7-0.7-0.7-1.1
Locomotion velocity, hab. session 10.40.61.2-0.5-0.5-0.9-0.6-0.8-0.8-0.8-0.8-0.8-0.8-0.8-1.1
Time in familiar zone, hab. session 21.31.42.41.31.50.71.41.41.11.01.21.21.21.20.4
Time in novel zone, hab. session 22.82.93.9-1.5-1.8-1.2-1.9-2.0-1.8-1.6-1.7-1.8-1.7-1.7-1.3
Total zone transitions, hab. session 20.00.10.20.1-0.3-0.40.1-0.1-0.00.0-0.2-0.3-0.2-0.2-0.3
Total locomotion distance, hab. session 20.10.10.40.1-0.2-0.4-0.1-0.2-0.3-0.2-0.4-0.4-0.4-0.4-0.6
Locomotion velocity, hab. session 20.00.00.10.30.0-0.10.20.10.00.1-0.1-0.2-0.1-0.1-0.2
Novel to familiar place preference ratio1.21.32.2-0.9-1.0-0.9-1.1-1.5-1.2-1.1-1.2-1.2-1.2-1.2-1.0
Novelty place preference0.90.91.7-0.7-0.8-0.8-0.9-1.3-1.0-0.9-1.0-1.0-1.0-1.0-0.9
Time in novel zone, NPP test0.91.01.7-0.9-0.9-0.6-1.0-1.3-1.0-1.0-1.1-1.0-1.1-1.1-0.6
Total zone transitions, NPP test0.00.00.3-0.3-0.5-0.3-0.1-0.00.00.0-0.1-0.1-0.1-0.10.0
Total locomotion distance, NPP test0.10.20.4-0.4-0.6-0.3-0.4-0.2-0.3-0.3-0.5-0.5-0.5-0.5-0.2
Locomotion velocity, NPP test0.00.00.1-0.0-0.3-0.2-0.00.1-0.00.0-0.2-0.2-0.2-0.2-0.1
Intraocular pressure4.66.68.9-2.2-2.0-2.8-2.4-2.4-2.7-2.8-2.5-2.4-2.6-2.6-3.0
Delta distance traveled before/after self-admin3.13.24.11.51.62.01.61.71.81.81.91.82.01.92.0
Delta ambulatory time before/after self-admin4.25.26.32.02.02.42.12.12.32.32.42.32.52.42.4
Parametrial fat weight0.00.00.2-0.1-0.0-0.50.1-0.00.10.00.20.20.10.1-0.2
Pavlov. Cond. lever latency0.00.00.20.10.3-0.3-0.0-0.0-0.1-0.10.10.20.10.1-0.4
Pavlov. Cond. magazine entry latency0.00.00.0-0.2-0.20.2-0.1-0.2-0.1-0.1-0.0-0.1-0.0-0.00.1
Pavlov. Cond. change in total contacts0.70.81.80.60.41.30.81.01.00.90.70.60.70.71.3
Pavlov. Cond. index score0.10.10.4-0.5-0.6-0.0-0.4-0.5-0.3-0.3-0.3-0.4-0.3-0.30.1
Pavlov. Cond. latency score0.10.10.2-0.3-0.4-0.1-0.2-0.4-0.2-0.2-0.2-0.3-0.2-0.2-0.1
Pavlov. Cond. lever contacts0.10.10.3-0.4-0.60.2-0.2-0.2-0.0-0.1-0.3-0.4-0.3-0.30.3
Pavlov. Cond. magazine entry number0.20.20.80.80.9-0.20.50.30.20.30.20.50.20.2-0.5
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.3-0.3-0.4-0.3-0.2-0.3-0.2-0.4-0.3-0.4-0.4-0.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.6-0.7-0.8-0.1-0.5-0.6-0.4-0.4-0.4-0.5-0.4-0.4-0.0
Pavlov. Cond. response bias0.20.20.7-0.6-0.80.5-0.4-0.1-0.0-0.1-0.2-0.4-0.2-0.20.7
Pavlov. Cond. lever latency0.20.30.50.10.0-0.4-0.4-0.7-0.5-0.4-0.6-0.5-0.7-0.6-0.7
Pavlov. Cond. magazine entry latency0.10.10.1-0.4-0.3-0.00.10.30.20.10.30.20.30.30.3
Pavlov. Cond. change in total contacts0.10.10.5-0.7-0.70.0-0.20.30.10.00.0-0.00.00.00.6
Pavlov. Cond. index score0.10.10.3-0.6-0.60.1-0.10.30.20.10.20.10.20.20.5
Pavlov. Cond. latency score0.10.10.3-0.4-0.40.20.00.40.30.20.30.20.30.30.5
Pavlov. Cond. lever contacts0.40.61.00.10.20.60.61.00.80.70.90.80.90.91.0
Pavlov. Cond. magazine entry number0.00.10.30.60.50.10.2-0.10.00.1-0.10.1-0.0-0.1-0.2
Pavlov. Cond. intertrial magazine entries0.60.91.81.31.20.81.10.90.91.10.70.90.80.70.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.6-0.60.0-0.10.30.20.00.20.00.20.20.5
Pavlov. Cond. response bias0.10.20.6-0.5-0.50.20.10.50.40.20.40.30.40.40.8
Time in closed arm before self-admin3.14.05.31.61.72.21.82.02.12.02.02.22.02.02.3
Time in closed arm after self-admin1.21.31.71.01.11.31.11.21.21.21.01.21.01.01.3
Time in open arm before self-admin1.82.02.6-1.4-1.5-1.6-1.4-1.4-1.4-1.3-1.4-1.4-1.4-1.4-1.3
Time in open arm after self-admin0.91.01.4-1.1-1.2-1.0-1.1-1.0-1.0-1.0-0.9-1.0-0.9-0.9-0.8
Bone: periosteal estimation0.00.10.10.20.40.20.30.30.30.20.40.30.30.40.2
Bone: periosteal perimeter0.20.40.6-0.5-0.3-0.8-0.4-0.5-0.6-0.7-0.6-0.5-0.7-0.6-0.8
Bone: post-yield work0.30.50.9-0.1-0.3-0.8-0.3-0.5-0.6-0.7-0.9-0.8-0.9-0.9-0.9
Progressive ratio test 1 active lever presses0.10.10.4-0.1-0.10.3-0.2-0.00.1-0.10.30.10.20.40.6
Progressive ratio test 1 breakpoint0.10.10.4-0.2-0.10.3-0.2-0.00.1-0.10.20.10.20.30.7
Progressive ratio test 1 inactive lever presses0.10.10.2-0.4-0.5-0.2-0.4-0.3-0.2-0.3-0.2-0.3-0.2-0.00.1
Progressive ratio test 2 active lever presses0.00.00.1-0.1-0.00.1-0.2-0.2-0.0-0.10.20.00.20.30.2
Progressive ratio test 2 breakpoint0.00.00.1-0.1-0.1-0.0-0.3-0.3-0.2-0.20.1-0.10.10.20.1
Progressive ratio test 2 inactive lever presses0.91.52.0-1.1-1.2-1.4-1.2-1.2-1.2-1.3-1.2-1.3-1.2-1.0-1.3
Incentive Sensitization - Responses0.00.00.10.20.1-0.20.0-0.1-0.10.00.1-0.00.10.2-0.3
Incentive Sensitization - Breakpoint0.00.00.10.30.2-0.20.1-0.10.00.10.20.00.10.2-0.3
Sum of active levers in priming session hrs 5-60.30.30.7-0.0-0.2-0.6-0.3-0.4-0.5-0.4-0.7-0.6-0.8-0.7-0.8
Progressive ratio0.30.41.31.01.10.40.70.70.40.40.50.50.40.5-0.1
Food seeking constrained by brief footshock1.82.23.41.81.71.31.81.81.61.61.21.41.21.21.0
Seeking ratio, punishment vs. effort0.71.02.10.50.31.00.91.01.21.20.90.90.90.91.5
Retroperitoneal fat weight0.21.12.6-0.8-0.7-1.6-0.7-1.1-0.9-0.9-0.9-0.8-0.9-0.9-1.5
Reaction time number correct0.71.31.9-1.0-1.2-1.0-1.1-1.0-1.1-1.0-1.3-1.3-1.4-1.2-0.9
Reaction time mean minus median0.71.73.7-1.5-1.9-0.8-1.5-1.1-1.1-1.1-1.5-1.4-1.2-1.5-0.3
Reaction time mean minus median AUC0.61.42.7-1.4-1.6-0.8-1.4-1.1-1.2-1.1-1.3-1.2-1.1-1.3-0.5
Reaction time num false alarms5.27.39.3-2.9-3.0-3.0-2.6-2.6-2.6-2.6-2.6-2.6-2.7-2.6-2.4
Reaction time num false alarms AUC4.26.68.3-2.7-2.9-2.9-2.5-2.4-2.5-2.5-2.5-2.6-2.7-2.5-2.3
Reaction time trials correct on left0.71.31.9-1.0-1.2-1.0-1.1-1.0-1.1-1.0-1.3-1.3-1.4-1.2-0.9
Reaction time trials on left0.81.52.1-1.1-1.3-1.1-1.2-1.1-1.2-1.1-1.3-1.3-1.5-1.3-0.9
Reaction time mean1.93.04.7-2.1-2.2-1.4-2.1-1.7-1.7-1.7-1.7-1.6-1.6-1.7-0.8
Reaction time mean AUC1.93.14.8-2.1-2.2-1.4-2.1-1.7-1.8-1.8-1.7-1.7-1.6-1.7-0.9
Median of all reaction times1.72.43.7-1.9-1.8-1.3-1.9-1.6-1.6-1.6-1.4-1.4-1.4-1.4-0.8
Reaction time omissions2.23.25.3-2.3-2.2-1.8-2.1-1.9-1.8-1.9-1.5-1.6-1.6-1.5-1.1
Reaction time false alarm rate1.82.43.5-1.8-1.7-1.9-1.5-1.5-1.5-1.6-1.4-1.4-1.4-1.4-1.5
Reaction time premature initiation rate3.54.86.42.42.41.52.52.32.32.22.32.32.32.31.3
Reaction time premature initiations1.01.82.71.61.50.81.61.41.41.41.31.41.31.30.6
Std. dev. reaction times1.01.93.9-1.7-2.0-1.0-1.6-1.2-1.3-1.3-1.5-1.4-1.3-1.5-0.4
Reaction time trials completed0.81.52.1-1.1-1.3-1.1-1.2-1.1-1.2-1.1-1.3-1.3-1.5-1.3-0.9
Reaction time trials AUC0.81.62.2-1.1-1.4-1.2-1.2-1.1-1.2-1.1-1.4-1.4-1.5-1.4-1.0
Run reversals in cocaine runway, females0.40.40.9-0.9-0.9-0.3-0.7-0.6-0.5-0.6-0.6-0.7-0.6-0.7-0.2
Run reversals in cocaine runway, males0.10.10.4-0.2-0.2-0.0-0.4-0.6-0.4-0.2-0.4-0.3-0.3-0.5-0.2
Latency to leave start box in cocaine runway0.30.40.7-0.3-0.3-0.7-0.5-0.5-0.6-0.6-0.7-0.7-0.6-0.5-0.9
Latency to leave start box in cocaine runway, F0.70.81.0-0.6-0.7-0.6-0.9-0.9-1.0-0.9-0.9-1.0-0.9-0.9-0.9
Latency to leave start box in cocaine runway, M0.20.20.40.50.5-0.30.70.60.40.40.30.30.30.4-0.2
Std. dev. time between licks in bursts0.40.50.90.40.50.70.50.40.60.70.90.90.90.90.6
Total sessions with >9 infusions0.00.00.0-0.10.00.1-0.1-0.1-0.0-0.20.10.00.10.20.2
Short access day 1 total inactive lever presses0.10.10.50.1-0.00.50.10.20.30.20.40.20.40.50.7
Short access day 10 total inactive lever presses0.10.30.40.40.30.40.60.60.70.60.60.60.60.60.5
Short access day 1 total infusions0.50.71.0-0.9-0.9-0.9-1.0-0.9-0.9-1.0-0.7-0.9-0.8-0.6-0.6
Short access day 10 total infusions0.00.10.30.30.30.00.10.00.10.10.30.20.30.5-0.1
Short access total infusions0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.2-0.30.0-0.2-0.00.2-0.1
Short access day 1 locomotion2.12.53.4-1.4-1.6-1.5-1.6-1.6-1.6-1.6-1.6-1.8-1.6-1.6-1.4
Short access day 10 total locomotion0.00.10.1-0.3-0.2-0.3-0.3-0.3-0.3-0.4-0.2-0.3-0.2-0.3-0.2
Short access total locomotion0.40.50.7-0.6-0.6-0.8-0.7-0.7-0.8-0.8-0.7-0.8-0.7-0.7-0.7
One hour access (0.3 mA shock)0.40.51.9-0.3-0.3-1.1-0.3-0.5-0.7-0.6-0.5-0.7-0.5-0.4-1.4
Compulsive drug intake0.20.21.40.10.1-0.40.1-0.1-0.4-0.2-0.5-0.3-0.5-0.6-1.2
One hour access (shock baseline)0.10.20.6-0.3-0.3-0.7-0.3-0.4-0.5-0.5-0.3-0.5-0.3-0.1-0.7
Social response proportion0.10.10.3-0.20.00.4-0.1-0.10.20.20.40.40.40.40.5
Social responses0.10.10.4-0.4-0.2-0.7-0.2-0.4-0.3-0.3-0.1-0.1-0.1-0.1-0.6
Social time1.52.02.81.51.61.41.31.11.21.31.71.51.61.71.0
Soleus weight0.00.10.5-0.10.3-0.5-0.2-0.6-0.3-0.40.2-0.10.10.2-0.7
Bone: stiffness0.10.10.5-0.1-0.50.50.10.10.30.2-0.00.0-0.1-0.00.7
Tibialis anterior weight0.41.51.9-1.3-1.4-0.9-1.3-1.1-1.2-1.2-1.3-1.3-1.4-1.3-0.7
Time to tail flick, vehicle, before self-admin0.10.10.90.50.6-0.30.2-0.1-0.2-0.2-0.1-0.10.1-0.1-0.9
Time to tail flick, vehicle, after self-admin0.50.72.01.31.40.31.00.70.60.70.70.90.60.7-0.3
Time to tail flick, test, before self-admin1.21.21.7-0.9-0.9-1.2-1.0-1.0-1.2-1.2-1.1-1.1-1.1-1.1-1.3
Time to tail flick, test, after self-admin0.70.71.20.90.91.10.81.00.80.80.60.80.80.60.9
Delta time to tail flick, vehicle, before/after SA0.30.30.40.60.60.40.60.60.50.60.60.60.30.60.3
Delta time to tail flick, test, before/after SA1.51.63.90.70.81.70.91.21.31.21.11.21.31.12.0
Tibia length0.30.72.4-1.5-1.50.1-0.9-0.4-0.4-0.6-0.7-0.6-0.7-0.70.9
Ambulatory time before self-admin2.74.04.7-2.2-2.1-1.6-2.2-2.0-2.0-2.0-2.1-2.0-2.1-2.1-1.4
Ambulatory time after self-admin0.30.41.50.20.21.10.30.40.60.60.50.60.50.51.2
Bone: tissue strength0.20.20.40.10.30.50.20.00.40.40.60.60.50.60.6
Total heroin consumption0.20.30.5-0.5-0.5-0.7-0.4-0.4-0.5-0.5-0.5-0.4-0.7-0.5-0.6
Bone: trabecular number1.72.87.32.72.21.81.91.31.51.81.31.31.31.30.8
Bone: trabecular spacing0.81.02.7-1.6-1.2-1.1-1.3-1.0-1.0-1.0-0.7-0.7-0.7-0.7-0.6
Bone: trabecular thickness3.03.85.82.41.92.32.01.92.02.11.61.71.61.61.9
Bone: trabecular tissue density0.71.02.1-1.0-1.4-0.9-0.9-0.6-0.8-0.8-1.2-1.2-1.2-1.2-0.5
Water consumed over 24 hours2.53.43.61.81.81.81.91.91.91.81.91.91.81.91.7
Number of responses in last shaping day2.12.33.3-1.3-1.4-1.8-1.3-1.4-1.5-1.4-1.6-1.6-1.6-1.6-1.7