Hub : Genes

Snu13

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Snu13 0.04 0.03 3.2e-04 0.03 0.03 0.01 0.02 8.2e-04 1.7e-03 1.5e-02 5.1e-03
2 PL mRNA stability Snu13 0.02 0.02 5.1e-03 0.02 0.02 0 0.01 7.0e-03 5.2e-03 3.1e-01 8.3e-03
3 Brain gene expression Snu13 0.09 0.04 1.2e-09 0.1 0.09 0.1 0.1 1.7e-09 6.2e-09 3.1e-09 3.5e-09
4 Adipose mRNA stability Snu13 0.08 0.04 2.5e-10 0.07 0.06 0.06 0.07 3.2e-08 9.5e-08 1.1e-07 7.3e-08
5 NAcc mRNA stability Snu13 0.03 0.02 3.8e-05 0.04 0.03 0.04 0.04 6.0e-07 1.2e-05 4.6e-06 9.5e-07
6 NAcc gene expression Snu13 0.03 0.02 7.2e-05 0.03 0.02 0.03 0.02 3.4e-05 1.7e-04 6.8e-05 2.1e-04
7 Liver mRNA stability Snu13 0.04 0.03 4.1e-04 0.01 0.02 0.01 0.01 3.0e-02 4.4e-03 3.5e-02 2.2e-02
8 pVTA gene expression Snu13 0.09 0.06 5.2e-05 0.07 0.04 0.04 0.06 5.4e-06 1.7e-04 1.4e-04 2.2e-05
9 Adipose gene expression Snu13 0.25 0.14 2.8e-14 0.11 0.12 0.12 0.11 1.8e-12 7.9e-13 1.9e-13 1.8e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.30.51.11.00.8-0.60.80.6-0.71.00.2-0.3
Area under the delay curve0.20.31.00.80.5-0.50.10.2-0.30.10.4-1.0
BMI with tail0.82.64.3-1.7-2.01.7-2.1-1.71.6-1.31.20.9
BMI without tail0.10.20.9-0.8-0.40.2-0.40.2-0.10.0-0.30.9
Body weight1.14.77.3-2.5-2.42.1-2.4-2.72.6-2.00.80.9
Weight adjusted by age0.20.31.6-0.2-0.10.40.1-0.20.3-0.5-1.30.0
Bone surface0.20.41.50.30.6-0.40.70.7-0.70.4-1.20.0
Bone volume0.00.10.20.40.3-0.10.30.3-0.30.3-0.4-0.0
Breakpoint value in progressive ratio session0.10.10.3-0.50.1-0.10.2-0.0-0.00.40.60.5
Number of licking bursts0.40.60.90.50.9-0.81.00.9-1.00.6-0.4-0.6
Context. condit. distance diff. score6.37.610.2-2.9-3.23.2-3.1-2.92.9-3.10.51.7
Locomotion velocity, session 10.40.42.7-0.6-0.00.10.20.2-0.2-0.6-1.60.5
Locomotion distance, session 12.22.84.01.52.0-1.92.01.9-1.91.0-1.6-0.8
Locomotion velocity, session 20.30.30.4-0.5-0.50.6-0.6-0.40.4-0.5-0.60.6
Locomotion distance, session 22.53.54.81.92.2-1.92.02.1-2.12.00.1-1.5
Locomotion velocity, session 30.30.41.4-0.3-0.40.3-0.4-0.40.4-0.9-1.20.6
Locomotion distance, session 31.11.22.21.31.2-1.31.21.1-1.00.2-1.5-0.6
Stereotopy head waving bouts, day 30.70.81.2-1.0-1.01.0-1.1-1.00.9-0.80.10.7
Stereotopy head waving duration, day 33.33.95.7-2.4-2.32.4-2.3-2.01.9-1.8-0.01.6
Locomotion velocity, session 70.10.10.40.3-0.3-0.1-0.3-0.50.5-0.7-0.10.1
Locomotion distance, session 70.60.82.31.50.4-0.80.2-0.00.20.11.2-1.5
Stereotopy head waving bouts, day 73.13.55.6-1.9-1.81.8-1.5-1.61.5-2.1-2.12.4
Stereotopy head waving duration, day 72.83.37.2-1.8-1.81.7-1.5-1.61.5-1.8-1.82.7
Locomotion velocity, session 82.42.96.4-2.5-1.82.3-1.9-1.41.4-1.70.11.0
Locomotion distance, session 80.81.11.9-1.1-1.21.4-1.3-0.80.8-1.30.11.0
Degree of sensitization distance2.32.46.1-0.9-1.61.4-1.8-1.71.7-0.72.50.2
Degree of sensitization stereotypy2.42.64.3-1.7-1.61.5-1.2-1.31.3-1.8-1.92.1
Conditioned locomotion0.60.71.5-0.3-1.01.0-1.0-0.70.7-1.2-0.30.4
Cocaine response after cond. corrected0.10.10.2-0.2-0.30.1-0.0-0.40.4-0.4-0.20.4
Cocaine response after cond. not corrected0.10.10.3-0.3-0.30.2-0.1-0.10.1-0.3-0.30.6
Cocaine response before conditioning0.10.20.60.00.3-0.1-0.10.8-0.80.4-0.10.1
Saline control response0.40.61.7-1.0-0.50.6-0.70.3-0.3-0.6-0.81.3
Bone: connectivity density0.10.20.40.60.4-0.30.50.2-0.20.60.2-0.4
Bone: cortical apparent density1.01.42.01.41.3-1.41.21.3-1.21.0-0.3-1.0
Bone: cortical area1.32.03.5-1.9-1.71.6-1.6-1.51.4-1.30.60.5
Bone: cortical porosity0.30.30.5-0.5-0.70.5-0.7-0.60.7-0.30.20.6
Bone: cortical porosity1.41.52.2-1.4-1.51.4-1.4-1.31.4-1.0-0.01.2
Bone: cortical thickness0.50.83.9-0.7-0.50.5-0.7-0.70.6-0.12.0-1.1
Bone: cortical thickness0.80.93.7-0.8-0.60.9-0.8-0.50.5-0.31.9-1.3
Bone: cortical tissue density0.91.31.81.31.2-1.31.21.2-1.20.9-0.3-1.0
Condit. Reinf. active minus inactive responses0.20.20.50.70.5-0.50.30.5-0.30.50.4-0.6
Condit. Reinf. active-inactive response ratio0.30.30.4-0.4-0.60.5-0.7-0.50.6-0.60.10.6
Condit. Reinf. active responses1.41.72.81.71.3-1.31.11.6-1.51.50.3-0.7
Condit. Reinf. inactive responses2.83.45.62.21.9-1.81.72.4-2.42.00.1-0.9
Incentive salience index mean0.60.71.61.30.8-0.80.50.8-0.80.90.6-1.0
Condit. Reinf. lever presses0.91.33.11.71.2-1.10.81.3-1.21.20.4-0.8
Condit. Reinf. active minus inactive responses0.20.21.0-0.40.10.0-0.1-0.00.00.21.0-0.9
Condit. Reinf. active-inactive response ratio0.30.31.4-0.4-0.0-0.00.0-0.40.40.31.2-0.8
Condit. Reinf. active responses0.40.61.1-1.0-0.71.0-0.9-0.60.6-0.70.6-0.2
Condit. Reinf. inactive responses0.81.02.1-0.9-1.11.4-1.4-0.80.8-1.40.0-0.1
Condit. Reinf. lever presses0.20.30.80.30.7-0.50.60.7-0.70.90.3-0.1
Condit. Reinf. lever reinforcers received0.20.30.5-0.6-0.40.7-0.7-0.40.4-0.30.6-0.3
Conditioned reinforcement - actives0.40.61.4-0.6-0.80.5-0.8-0.70.7-0.90.8-1.2
Conditioned reinforcement - inactives0.40.63.0-0.5-0.10.1-0.40.4-0.40.41.7-1.4
Conditioned locomotion1.31.73.1-1.0-1.51.2-1.6-1.11.2-1.11.8-0.9
Patch foraging indifference point 0 sec0.40.71.70.40.8-0.80.61.1-1.11.30.1-0.3
Patch foraging indifference point AUC0.30.51.40.40.8-0.90.60.6-0.50.1-0.6-1.2
Delay disc. indifference point, 0s delay0.90.91.8-0.8-1.21.1-1.4-0.80.8-0.80.90.9
Delay disc. indifference point, 16s delay0.91.01.91.41.3-1.21.10.6-0.60.9-0.1-1.3
Delay disc. indifference point, 2s delay0.10.20.40.4-0.10.2-0.50.1-0.1-0.40.6-0.6
Delay disc. indifference point, 24s delay0.40.51.10.50.5-0.80.8-0.50.5-0.4-0.8-1.0
Delay disc. indifference point, 4s delay0.20.21.1-0.20.10.3-0.40.3-0.40.11.0-0.7
Delay disc. indifference point, 8s delay0.70.82.21.51.0-1.10.60.7-0.80.60.3-1.0
Indifference point function ln k0.51.01.8-0.9-1.21.3-1.0-1.01.0-0.70.20.9
Indifference point function log k0.51.01.8-0.9-1.21.3-1.0-1.01.0-0.70.20.9
Patch foraging total patch changes 0 sec0.40.82.00.50.9-0.90.81.2-1.21.4-0.0-0.3
Patch foraging total patch changes 12 sec0.00.00.2-0.20.2-0.2-0.00.2-0.20.2-0.1-0.5
Patch foraging total patch changes 18 sec0.10.20.5-0.10.4-0.20.10.6-0.50.60.2-0.7
Patch foraging total patch changes 24 sec0.20.40.70.10.7-0.80.50.6-0.70.5-0.8-0.3
Patch foraging total patch changes 6 sec0.30.41.0-0.30.6-0.30.41.0-1.00.8-0.1-0.7
Patch foraging time to switch 0 sec0.10.21.00.80.0-0.30.10.1-0.10.3-0.41.0
Patch foraging water rate 0 sec0.10.31.1-1.00.30.20.20.5-0.50.60.4-0.2
Patch foraging water rate 12 sec0.30.71.10.10.7-0.71.10.9-0.90.8-0.80.9
Patch foraging water rate 18 sec0.91.33.20.21.4-1.01.81.1-1.11.5-0.90.3
Patch foraging water rate 24 sec0.20.21.3-1.1-0.20.50.1-0.20.20.30.10.6
Patch foraging water rate 6 sec0.91.22.30.51.1-0.91.31.3-1.30.8-1.50.9
Seeking ratio, delayed vs. immediate footshock3.03.76.32.52.3-2.42.11.7-1.82.3-0.3-0.4
Distance traveled before self-admin0.40.61.40.80.5-0.40.30.6-0.61.01.2-1.0
Distance traveled after self-admin0.30.41.4-0.30.2-0.50.10.7-0.70.70.4-1.2
Extensor digitorum longus weight0.10.60.9-0.20.6-0.90.61.0-1.00.8-0.50.8
Bone: elastic displacement0.50.51.6-1.2-0.30.4-0.0-0.30.3-0.5-1.01.3
Bone: elastic work2.43.16.3-2.5-2.02.1-1.7-1.81.8-1.40.31.4
Bone: endosteal estimation1.02.35.4-1.7-1.41.5-1.1-0.90.9-1.3-1.92.3
Bone: endosteal perimeter1.73.65.6-1.8-2.11.8-1.7-1.71.7-2.2-1.72.4
Epididymis fat weight2.06.911.5-1.9-3.02.7-3.1-3.43.3-2.61.70.7
Delta time in closed arm before/after self-admin0.60.51.50.0-0.40.6-0.8-0.80.8-0.50.8-1.2
Delta time in open arm before/after self-admin0.50.51.60.10.20.10.60.9-0.8-0.1-1.31.0
Diff in mean of infusions in LGA sessions0.30.31.1-0.5-0.20.4-0.3-0.70.7-0.30.2-1.0
Delay discount exponential model param0.30.31.1-0.8-0.50.5-0.2-0.30.4-0.1-0.31.0
Extinction: sum of active levers before priming0.91.01.6-1.3-1.01.2-1.0-1.21.1-0.80.80.3
Active lever presses in extinction session 60.40.41.0-0.9-0.50.8-0.5-0.50.4-0.30.31.0
Bone: final force1.21.92.8-1.4-1.41.6-1.5-1.71.6-1.01.2-0.3
Bone: final moment1.32.13.0-1.7-1.61.7-1.6-1.71.7-1.11.2-0.1
Food consumed during 24 hour testing period1.31.82.4-1.4-1.41.5-1.5-1.61.5-1.11.2-0.6
Glucose0.10.20.40.50.2-0.1-0.20.3-0.40.60.6-0.2
Heart weight6.610.217.3-4.2-4.04.1-3.9-2.72.7-3.01.30.9
Delay discount hyperbolic model param0.20.21.0-0.7-0.40.30.0-0.30.40.0-0.51.0
Intermittent access intake day 1-15 change0.20.30.70.90.6-0.80.40.5-0.40.80.1-0.4
Intermittent access intake escalation0.20.51.10.90.7-1.00.60.7-0.60.8-0.1-0.2
Intermittent access intake escalation 20.50.61.41.00.8-1.20.70.6-0.60.9-0.2-0.0
Intermitt. access day 1 inactive lever presses0.31.15.2-1.0-0.71.1-1.1-0.50.50.22.3-0.6
Intermitt. access day 15 inactive lever presses0.51.05.8-0.5-0.20.6-0.70.4-0.40.62.4-0.9
Intermitt. access escalation Index0.10.20.40.40.5-0.40.40.6-0.60.5-0.0-0.2
Intermittent access day 1 total infusions0.60.91.8-0.6-0.91.0-1.0-0.70.7-0.71.3-1.3
Intermittent access day 15 total infusions0.10.20.70.60.2-0.40.00.5-0.50.10.4-0.8
Intermittent access terminal intake (last 3 days)0.10.20.70.70.0-0.5-0.10.0-0.0-0.10.2-0.9
Intermittent access total infusions0.30.31.10.2-0.40.2-0.5-0.40.4-0.40.8-1.0
Intermittent access day 1 locomotion0.30.41.9-0.0-0.30.7-0.50.2-0.20.21.4-0.8
Intermittent access day 15 total locomotion0.10.10.30.1-0.30.3-0.4-0.40.4-0.10.5-0.4
Intermittent access total locomotion0.30.31.00.1-0.40.3-0.5-0.50.5-0.11.0-0.8
Intermittent access standard deviation0.30.62.60.0-0.80.3-0.9-0.80.9-0.01.6-0.6
Left kidney weight9.845.668.9-8.3-7.98.1-7.9-6.96.9-6.82.71.8
Right kidney weight11.050.270.2-8.3-8.18.4-8.2-7.67.6-6.73.91.5
Cocaine induced anxiety0.91.23.9-1.0-0.60.2-0.4-2.01.9-0.41.2-0.4
Post-drug Anxiety0.20.20.4-0.10.2-0.70.6-0.60.50.2-0.0-0.1
Baseline Anxiety1.82.04.61.41.3-1.21.22.1-2.10.7-1.5-0.1
Tail length0.41.53.90.41.2-1.21.41.3-1.20.9-2.00.7
Length with tail0.21.02.2-1.5-0.90.9-0.7-1.21.2-1.0-0.70.6
Length without tail1.75.49.6-2.3-2.62.5-2.5-3.12.9-2.11.20.4
Times rat made contact with spout0.70.81.0-0.9-0.81.0-1.0-0.80.8-0.90.9-0.9
Lifetime Intake0.81.02.9-0.3-0.80.7-1.0-0.80.8-0.61.7-1.4
Liver weight, left1.01.74.2-0.9-1.41.1-1.2-1.21.2-2.1-1.01.3
Liver weight, right2.13.66.3-1.5-2.21.7-2.0-2.02.1-2.5-0.81.9
Locomotor activity1.93.04.3-2.1-2.01.6-1.7-1.81.9-1.7-0.11.8
Locomotor testing distance0.10.10.50.50.3-0.70.30.2-0.10.3-0.10.3
Locomotor testing rearing0.91.93.2-1.1-1.71.4-1.8-1.41.5-1.70.50.5
Locomotion in novel chamber0.81.03.30.20.0-0.30.31.8-1.8-0.3-1.30.7
Locomotion in novel chamber post-restriction0.71.13.01.71.1-1.21.10.9-0.90.8-0.7-0.4
Fecal boli incidents, locomotor time 10.10.10.30.30.6-0.30.40.2-0.40.5-0.30.1
Change in fecal boli incidents, locomotor task0.70.61.9-0.7-0.80.6-0.4-0.91.0-1.4-0.70.3
Time >=10cm from walls, locomotor time 10.10.10.4-0.0-0.30.2-0.2-0.70.5-0.20.0-0.1
Bouts of movement, locomotor time 10.60.62.20.2-0.30.1-0.3-1.51.4-0.60.9-0.1
Total resting periods, locomotor time 10.50.61.80.5-0.1-0.1-0.1-1.21.1-0.21.3-0.6
Rest time, locomotor task time 10.91.14.70.2-0.60.5-0.9-1.11.1-0.42.2-1.1
Distance moved, locomotor task time 10.40.61.0-1.0-0.81.0-0.8-0.30.3-0.8-0.80.6
Vertical activity count, locomotor time 10.10.10.6-0.5-0.1-0.0-0.00.3-0.10.1-0.80.5
Time >=10cm from walls, locomotor time 20.10.20.50.70.4-0.50.50.3-0.30.3-0.7-0.2
Bouts of movement, locomotor time 20.20.41.70.2-0.40.2-0.4-0.50.3-0.21.3-1.0
Total resting periods, locomotor time 20.30.41.90.2-0.30.1-0.3-0.50.3-0.11.4-1.2
Rest time, locomotor task time 20.10.20.60.30.4-0.40.20.0-0.10.20.8-0.6
Distance moved, locomotor task time 20.60.71.4-0.8-1.11.0-1.2-0.50.5-1.1-0.20.3
Vertical activity count, locomotor time 20.20.20.4-0.5-0.60.4-0.6-0.00.2-0.5-0.70.0
Light reinforcement 10.10.31.3-0.6-0.40.2-0.30.2-0.2-0.6-1.20.8
Light reinforcement 20.50.71.3-0.2-1.10.4-1.1-1.11.1-1.00.40.2
Bone: marrow area1.12.55.6-1.8-1.41.6-1.2-0.90.9-1.4-1.92.4
Bone: maximum diameter3.46.39.7-3.1-3.02.9-2.8-2.62.6-2.50.21.4
Bone: maximum force1.93.34.7-2.1-2.02.2-2.1-2.12.0-1.51.4-0.3
Bone: maximum moment2.23.95.9-2.4-2.22.3-2.2-2.22.1-1.61.4-0.2
Mean time between licks in bursts0.20.60.90.90.8-0.90.81.0-0.90.8-0.20.1
Mean num. licks in bursts1.42.23.1-1.4-1.71.7-1.7-1.71.8-1.50.80.1
Cd content in liver1.31.42.7-1.6-1.21.3-1.1-1.21.2-1.70.4-0.4
Co content in liver0.30.31.3-0.7-0.00.1-0.1-0.00.00.11.1-1.1
Cu content in liver5.86.99.72.72.9-2.73.03.1-3.12.9-1.4-0.6
Fe content in liver0.80.92.4-1.5-1.11.1-1.0-0.50.5-0.4-0.41.3
K content in liver1.00.91.41.01.2-0.61.11.1-1.21.1-0.3-0.6
Mg content in liver1.21.21.81.41.2-0.71.01.1-1.11.30.4-1.3
Mn content in liver0.10.10.5-0.2-0.10.7-0.30.1-0.2-0.5-0.50.1
Na content in liver2.02.23.01.71.6-1.41.71.7-1.71.7-0.7-0.1
Rb content in liver0.30.41.1-1.0-0.30.5-0.4-0.30.2-0.20.7-1.1
Se content in liver0.50.61.10.80.8-0.81.00.7-0.80.5-1.00.2
Sr content in liver2.11.82.51.31.5-1.61.41.5-1.51.40.2-1.0
Zn content in liver0.10.10.50.10.20.10.30.2-0.3-0.1-0.7-0.3
Bone: minimum diameter0.50.81.2-1.1-1.10.9-0.9-0.80.7-1.0-0.71.0
Time in familiar zone, hab. session 10.20.20.50.1-0.10.0-0.1-0.40.5-0.7-0.4-0.7
Time in novel zone, hab. session 11.11.14.0-1.7-1.01.2-0.8-0.30.3-0.3-0.12.0
Total zone transitions, hab. session 12.94.06.11.92.4-2.22.42.5-2.41.4-1.6-0.5
Total locomotion distance, hab. session 11.72.45.51.21.5-1.41.61.9-1.80.6-2.30.5
Locomotion velocity, hab. session 12.02.84.71.61.8-1.61.82.2-2.00.9-2.00.0
Time in familiar zone, hab. session 20.30.31.00.3-0.2-0.30.10.1-0.2-0.6-1.00.9
Time in novel zone, hab. session 20.30.31.3-1.1-0.10.6-0.3-0.20.20.30.7-0.2
Total zone transitions, hab. session 20.91.12.70.81.2-0.70.91.6-1.60.8-0.3-1.0
Total locomotion distance, hab. session 20.81.12.50.91.0-0.70.91.6-1.50.9-0.3-1.0
Locomotion velocity, hab. session 21.41.93.91.31.4-1.11.32.0-1.91.3-0.4-1.2
Novel to familiar place preference ratio3.33.66.9-2.6-1.82.1-1.3-1.91.8-1.7-0.62.5
Novelty place preference4.34.68.4-2.9-2.12.3-1.6-2.22.2-2.0-0.62.6
Time in novel zone, NPP test5.35.610.4-3.2-2.32.6-1.8-2.42.4-2.3-0.62.7
Total zone transitions, NPP test2.63.76.51.52.2-1.82.22.5-2.41.3-1.7-1.1
Total locomotion distance, NPP test1.41.93.31.11.6-1.21.51.8-1.71.1-0.9-1.2
Locomotion velocity, NPP test2.33.24.91.82.0-1.81.92.2-2.11.4-1.1-1.4
Intraocular pressure0.30.40.9-0.4-0.60.5-0.5-0.80.8-1.00.2-0.1
Delta distance traveled before/after self-admin0.70.82.5-1.6-1.00.7-0.8-0.50.5-1.1-0.7-0.1
Delta ambulatory time before/after self-admin0.91.13.8-1.9-1.11.0-0.9-0.60.6-1.3-0.80.1
Parametrial fat weight0.10.20.70.8-0.1-0.2-0.1-0.20.2-0.5-0.70.2
Pavlov. Cond. lever latency0.60.71.8-1.3-0.90.9-0.6-0.80.8-1.0-0.40.6
Pavlov. Cond. magazine entry latency0.91.12.51.41.0-1.00.70.6-0.60.91.1-1.6
Pavlov. Cond. change in total contacts1.41.53.31.31.2-1.00.71.2-1.11.21.0-1.8
Pavlov. Cond. index score0.70.92.31.30.8-0.80.30.4-0.40.81.2-1.5
Pavlov. Cond. latency score0.50.71.51.10.7-0.70.30.4-0.40.81.1-1.2
Pavlov. Cond. lever contacts1.72.14.52.11.6-1.61.21.4-1.41.60.6-1.0
Pavlov. Cond. magazine entry number1.21.54.6-1.6-1.11.1-0.6-0.60.6-0.9-1.32.1
Pavlov. Cond. intertrial magazine entries0.81.01.70.61.2-1.11.31.1-1.11.3-0.3-0.1
Pavlov. Cond. lever-magazine prob. diff.0.91.12.91.51.0-1.00.50.5-0.50.91.1-1.7
Pavlov. Cond. response bias1.51.84.12.01.3-1.30.80.8-0.81.21.1-2.0
Pavlov. Cond. lever latency0.70.92.8-0.5-1.00.7-0.9-1.21.1-1.7-0.2-0.3
Pavlov. Cond. magazine entry latency3.34.08.41.92.3-2.12.41.8-1.82.90.8-1.2
Pavlov. Cond. change in total contacts0.50.83.00.20.8-0.30.70.5-0.51.71.3-0.9
Pavlov. Cond. index score1.72.35.71.31.7-1.41.71.5-1.42.40.7-0.7
Pavlov. Cond. latency score2.23.06.91.52.0-1.71.91.7-1.72.60.8-0.9
Pavlov. Cond. lever contacts0.91.23.30.71.2-0.81.11.3-1.31.8-0.00.3
Pavlov. Cond. magazine entry number1.92.45.4-1.5-1.81.6-1.9-1.31.2-2.3-0.60.9
Pavlov. Cond. intertrial magazine entries2.43.66.2-1.9-2.02.2-2.5-1.71.7-1.91.8-1.3
Pavlov. Cond. lever-magazine prob. diff.1.92.56.21.41.8-1.61.81.5-1.52.50.6-0.6
Pavlov. Cond. response bias1.01.33.80.91.3-1.01.31.2-1.22.00.3-0.2
Time in closed arm before self-admin4.96.29.22.42.6-3.02.62.8-2.82.8-1.80.1
Time in closed arm after self-admin0.30.31.50.80.1-0.4-0.2-0.10.1-0.1-0.3-1.2
Time in open arm before self-admin0.10.10.20.20.00.10.1-0.50.4-0.3-0.10.0
Time in open arm after self-admin0.50.51.80.10.30.10.70.6-0.5-0.0-1.31.3
Bone: periosteal estimation1.42.94.8-2.2-1.91.9-1.6-1.51.4-1.6-1.01.9
Bone: periosteal perimeter3.45.88.1-2.5-2.82.5-2.5-2.52.5-2.7-0.72.2
Bone: post-yield work0.30.51.4-0.6-0.50.7-0.6-0.60.6-0.40.8-1.2
Progressive ratio test 1 active lever presses0.60.72.9-0.1-0.30.3-0.6-0.70.6-0.21.5-1.7
Progressive ratio test 1 breakpoint0.50.62.90.1-0.10.1-0.5-0.60.6-0.21.3-1.7
Progressive ratio test 1 inactive lever presses1.21.89.0-0.5-0.60.7-1.2-0.20.20.23.0-2.1
Progressive ratio test 2 active lever presses0.60.73.7-0.1-0.10.0-0.4-0.40.3-0.11.4-1.9
Progressive ratio test 2 breakpoint0.50.63.5-0.0-0.0-0.0-0.3-0.30.3-0.11.3-1.9
Progressive ratio test 2 inactive lever presses0.50.92.40.80.8-0.60.40.8-0.81.01.2-1.6
Incentive Sensitization - Responses0.20.31.8-0.00.3-0.20.10.3-0.30.20.5-1.3
Incentive Sensitization - Breakpoint0.20.31.9-0.10.1-0.1-0.00.1-0.10.10.7-1.4
Sum of active levers in priming session hrs 5-60.10.10.5-0.4-0.10.7-0.1-0.30.2-0.0-0.10.6
Progressive ratio0.10.20.5-0.20.4-0.30.30.1-0.20.70.50.5
Food seeking constrained by brief footshock1.31.52.4-1.4-1.40.6-1.4-1.51.5-1.40.9-0.3
Seeking ratio, punishment vs. effort0.50.81.3-0.4-1.00.6-1.0-0.91.1-1.10.4-1.0
Retroperitoneal fat weight3.715.625.7-3.7-4.44.1-4.4-5.05.1-4.01.71.1
Reaction time number correct0.81.62.81.71.3-1.61.51.0-1.00.5-1.60.7
Reaction time mean minus median0.20.41.6-0.8-0.70.8-0.40.00.1-0.5-0.41.3
Reaction time mean minus median AUC0.40.91.6-1.0-1.21.3-0.9-0.80.8-1.00.11.1
Reaction time num false alarms0.30.41.6-0.3-0.2-0.1-0.10.4-0.4-0.3-1.31.3
Reaction time num false alarms AUC0.30.51.9-0.3-0.0-0.20.10.5-0.6-0.3-1.41.2
Reaction time trials correct on left0.81.62.81.71.3-1.61.51.0-1.00.5-1.60.7
Reaction time trials on left0.91.72.91.71.3-1.61.51.1-1.00.5-1.70.7
Reaction time mean0.10.20.6-0.10.3-0.10.60.5-0.40.6-0.10.7
Reaction time mean AUC0.10.10.40.00.3-0.20.50.4-0.40.5-0.10.6
Median of all reaction times0.30.40.90.30.6-0.50.90.6-0.60.9-0.10.5
Reaction time omissions0.20.20.60.10.3-0.10.40.7-0.7-0.1-0.80.5
Reaction time false alarm rate0.20.31.1-1.0-0.70.5-0.7-0.00.0-0.4-0.10.6
Reaction time premature initiation rate0.30.31.3-0.00.5-0.70.50.4-0.31.10.5-0.5
Reaction time premature initiations0.30.61.40.70.9-1.20.90.5-0.51.1-0.1-0.3
Std. dev. reaction times0.30.61.3-1.1-0.90.9-0.6-0.20.2-0.7-0.21.1
Reaction time trials completed0.91.72.91.71.3-1.61.51.1-1.00.5-1.70.7
Reaction time trials AUC0.71.42.61.51.1-1.41.40.8-0.80.5-1.60.8
Run reversals in cocaine runway, females0.60.62.01.20.5-0.80.60.6-0.60.1-1.40.1
Run reversals in cocaine runway, males0.80.82.4-1.1-0.91.0-0.6-0.70.8-1.5-0.30.3
Latency to leave start box in cocaine runway0.20.20.6-0.2-0.30.1-0.4-0.80.8-0.20.40.1
Latency to leave start box in cocaine runway, F0.10.10.20.40.4-0.50.30.1-0.10.4-0.40.4
Latency to leave start box in cocaine runway, M0.90.91.5-0.8-1.00.7-1.0-1.21.2-0.71.1-0.2
Std. dev. time between licks in bursts1.11.62.90.91.4-1.11.41.6-1.51.7-0.1-0.4
Total sessions with >9 infusions4.65.59.5-2.1-2.42.6-2.7-2.32.3-1.83.1-1.7
Short access day 1 total inactive lever presses1.41.93.9-2.0-1.41.7-1.7-0.50.5-0.51.8-0.9
Short access day 10 total inactive lever presses0.30.81.5-1.2-1.20.6-1.1-0.60.6-1.00.50.8
Short access day 1 total infusions1.62.13.8-1.7-1.71.8-1.9-0.70.8-0.91.9-0.5
Short access day 10 total infusions1.21.53.4-0.4-1.11.0-1.4-1.31.3-0.71.9-1.2
Short access total infusions2.63.38.1-1.5-1.82.0-2.1-1.51.5-1.12.8-1.5
Short access day 1 locomotion0.60.72.3-0.5-0.91.0-1.2-0.40.5-0.21.5-0.6
Short access day 10 total locomotion0.30.62.40.80.10.1-0.10.8-0.80.81.5-0.3
Short access total locomotion1.01.24.9-0.4-1.01.2-1.3-0.60.6-0.32.2-0.9
One hour access (0.3 mA shock)0.40.51.30.90.4-1.00.40.4-0.40.50.5-1.2
Compulsive drug intake0.30.31.3-0.70.6-0.10.50.5-0.50.10.0-1.1
One hour access (shock baseline)0.30.42.11.40.1-0.90.10.0-0.00.40.3-0.6
Social response proportion0.20.20.6-0.8-0.40.6-0.4-0.10.00.50.70.2
Social responses0.10.20.7-0.40.2-0.40.20.5-0.5-0.0-0.80.1
Social time1.52.12.91.71.6-1.51.41.7-1.71.60.1-0.9
Soleus weight0.10.21.0-0.30.50.20.00.5-0.50.30.2-1.0
Bone: stiffness1.01.62.4-1.2-1.51.5-1.5-1.41.3-1.01.10.0
Tibialis anterior weight0.62.03.40.81.7-1.91.81.6-1.61.70.6-0.4
Time to tail flick, vehicle, before self-admin0.30.30.8-0.9-0.20.9-0.30.0-0.1-0.1-0.00.8
Time to tail flick, vehicle, after self-admin1.31.74.20.40.8-1.01.31.2-1.20.5-2.02.0
Time to tail flick, test, before self-admin0.50.61.4-0.2-0.80.4-0.9-1.00.9-1.20.20.0
Time to tail flick, test, after self-admin0.30.30.80.90.4-0.60.20.5-0.70.1-0.4-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.9-0.2-0.1-0.40.20.0-0.00.1-0.21.0
Delta time to tail flick, test, before/after SA2.12.14.11.21.5-1.31.42.0-2.01.6-1.0-0.3
Tibia length0.72.03.1-1.8-1.51.4-1.5-1.71.7-1.50.30.2
Ambulatory time before self-admin0.30.40.90.60.4-0.20.21.0-1.00.70.8-0.7
Ambulatory time after self-admin0.91.12.60.10.9-1.01.01.6-1.61.0-0.8-0.6
Bone: tissue strength0.20.20.6-0.8-0.40.2-0.1-0.50.5-0.4-0.30.4
Total heroin consumption0.30.41.0-1.0-0.40.8-0.5-0.50.5-0.40.8-0.0
Bone: trabecular number0.10.10.91.00.2-0.30.3-0.10.0-0.1-0.4-0.0
Bone: trabecular spacing1.11.52.0-1.3-1.31.3-1.4-1.41.4-1.21.0-0.5
Bone: trabecular thickness0.30.40.80.90.5-0.40.40.6-0.60.9-0.00.5
Bone: trabecular tissue density1.62.45.30.71.8-1.41.61.9-1.92.3-0.20.7
Water consumed over 24 hours0.40.61.5-1.2-0.71.0-0.7-0.70.7-0.70.5-0.3
Number of responses in last shaping day1.31.53.91.10.8-0.50.31.0-1.01.72.0-1.4