Snu13

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Snu13 0.05 0.04 8.7e-03 0.01 0.01 0 0.01 6.0e-02 1.2e-01 2.6e-01 1.3e-01
2 NAcc mRNA stability Snu13 0.05 0.04 2.1e-04 0.02 0.03 0.04 0.03 8.2e-04 1.1e-04 4.6e-05 2.3e-04
3 NAcc gene expression Snu13 0.07 0.06 2.1e-05 0.05 0.05 0.05 0.05 9.4e-07 3.3e-06 4.1e-06 1.5e-06
4 PL mRNA stability Snu13 0.02 0.01 6.3e-03 0.02 0.02 0.02 0.01 2.5e-03 4.0e-03 4.6e-03 7.5e-03
5 Adipose mRNA stability Snu13 0.08 0.04 4.6e-10 0.07 0.06 0.07 0.06 3.8e-08 1.3e-07 7.9e-08 1.4e-07
6 Brain mRNA stability Snu13 0.03 0.02 4.6e-04 0.03 0.03 0.03 0.02 1.1e-03 1.2e-03 1.0e-03 3.9e-03
7 Liver mRNA stability Snu13 0.04 0.03 6.4e-04 0 0.02 0.01 0.01 9.2e-02 6.1e-03 6.9e-02 5.7e-02
8 Adipose gene expression Snu13 0.38 0.24 3.1e-15 0.12 0.12 0.14 0.12 2.6e-13 1.9e-13 8.2e-15 3.8e-13
9 pVTA gene expression Snu13 0.1 0.06 1.3e-03 0.02 0.03 0.02 0.03 6.3e-02 2.5e-02 3.1e-02 2.7e-02
10 Brain gene expression Snu13 0.08 0.04 1.7e-10 0.08 0.11 0.12 0.12 8.4e-08 1.0e-10 7.0e-11 5.5e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.30.80.6-0.60.6-0.2-0.9-0.50.90.2-0.4-0.4
Area under the delay curve0.40.41.30.9-0.60.3-0.8-0.2-0.80.11.2-0.1-0.2
BMI with tail1.55.08.0-1.92.2-2.02.82.52.5-1.6-0.62.62.7
BMI without tail0.10.21.4-0.30.10.21.20.10.30.1-0.70.20.6
Body weight1.56.510.5-2.63.0-3.03.22.62.9-2.4-1.32.21.5
Weight adjusted by age0.30.41.2-0.50.2-0.3-0.2-0.20.1-0.5-0.9-0.9-1.1
Bone surface0.20.41.0-0.6-0.50.5-0.6-0.7-0.10.2-0.6-1.0-0.9
Bone volume0.10.10.3-0.4-0.10.2-0.1-0.3-0.00.1-0.5-0.5-0.4
Breakpoint value in progressive ratio session0.20.20.50.1-0.30.5-0.1-0.40.20.70.60.30.6
Number of licking bursts0.40.51.10.6-1.00.9-1.1-0.8-0.40.40.5-0.8-0.4
Context. condit. distance diff. score5.66.79.8-2.73.1-2.92.93.02.4-3.1-2.21.81.0
Locomotion velocity, session 10.40.50.9-0.9-0.20.0-0.9-0.1-0.0-0.7-0.9-1.0-0.9
Locomotion distance, session 12.43.16.81.6-1.91.8-2.6-1.9-1.71.00.3-2.1-1.6
Locomotion velocity, session 20.30.30.8-0.90.6-0.40.40.60.7-0.6-0.70.00.5
Locomotion distance, session 22.23.15.31.7-2.22.0-2.3-1.9-1.52.11.7-1.0-0.2
Locomotion velocity, session 30.40.41.6-0.70.6-0.50.00.30.1-1.0-1.3-0.5-0.5
Locomotion distance, session 31.51.63.11.5-1.00.9-1.8-1.4-1.40.1-0.0-1.7-1.5
Stereotopy head waving bouts, day 31.01.13.0-1.71.2-1.21.11.01.1-0.8-0.90.60.3
Stereotopy head waving duration, day 33.54.29.2-3.02.2-2.12.22.22.2-1.9-2.01.10.6
Locomotion velocity, session 70.20.20.60.20.8-0.70.30.30.2-0.8-0.2-0.00.1
Locomotion distance, session 70.40.52.01.30.1-0.2-0.3-0.2-0.40.21.40.40.6
Stereotopy head waving bouts, day 73.33.79.1-2.91.9-1.81.51.61.6-2.1-3.00.0-0.8
Stereotopy head waving duration, day 72.42.97.5-2.21.8-1.61.71.41.3-1.8-2.7-0.0-0.9
Locomotion velocity, session 82.22.65.9-2.41.5-1.41.12.02.1-1.6-1.31.21.0
Locomotion distance, session 80.60.91.7-1.21.0-0.80.91.30.8-1.3-1.10.60.3
Degree of sensitization distance3.13.16.1-1.11.7-1.72.21.91.7-0.60.72.52.3
Degree of sensitization stereotypy2.22.46.9-2.11.5-1.41.11.11.2-1.9-2.6-0.3-1.1
Conditioned locomotion0.60.61.6-0.40.8-0.80.71.00.3-1.3-1.20.1-0.5
Cocaine response after cond. corrected0.10.10.4-0.00.3-0.30.20.10.3-0.3-0.6-0.20.1
Cocaine response after cond. not corrected0.10.10.6-0.20.2-0.00.20.20.1-0.2-0.8-0.3-0.0
Cocaine response before conditioning0.10.10.50.1-0.50.7-0.20.0-0.50.40.2-0.2-0.2
Saline control response0.40.51.6-0.7-0.30.4-0.10.5-0.4-0.6-1.2-0.8-1.3
Bone: connectivity density0.10.10.40.2-0.20.30.0-0.7-0.10.60.2-0.2-0.4
Bone: cortical apparent density0.60.81.50.9-1.21.0-1.2-1.0-1.00.80.8-0.6-0.5
Bone: cortical area1.52.23.7-1.91.5-1.51.61.61.7-1.4-1.11.21.0
Bone: cortical porosity0.50.51.2-0.90.7-0.71.10.80.5-0.5-0.90.50.0
Bone: cortical porosity1.31.42.7-1.51.3-1.21.61.21.3-0.9-1.20.80.3
Bone: cortical thickness0.50.72.5-0.30.4-0.60.70.60.90.00.91.41.6
Bone: cortical thickness0.60.72.7-0.20.4-0.60.40.71.0-0.20.91.31.6
Bone: cortical tissue density0.60.81.40.8-1.10.9-1.2-1.0-1.00.80.8-0.5-0.4
Condit. Reinf. active minus inactive responses0.20.31.00.3-0.50.4-0.5-0.3-0.30.61.00.20.7
Condit. Reinf. active-inactive response ratio0.20.20.7-0.80.5-0.50.30.50.4-0.5-0.20.40.4
Condit. Reinf. active responses1.41.73.01.3-1.51.5-1.3-1.1-1.31.51.7-0.40.2
Condit. Reinf. inactive responses2.73.24.92.2-2.12.2-1.7-1.6-2.02.01.8-1.0-0.6
Incentive salience index mean0.60.72.50.8-0.90.8-0.8-0.6-0.71.01.60.10.8
Condit. Reinf. lever presses0.81.02.31.1-1.31.2-0.9-0.7-1.11.11.5-0.20.4
Condit. Reinf. active minus inactive responses0.20.30.7-0.5-0.20.0-0.50.10.40.30.70.60.8
Condit. Reinf. active-inactive response ratio0.40.41.1-0.70.2-0.30.10.10.90.40.91.01.1
Condit. Reinf. active responses0.40.61.9-1.40.4-0.60.00.91.0-0.7-0.10.70.8
Condit. Reinf. inactive responses0.70.82.1-1.20.7-0.80.41.40.8-1.5-0.60.50.5
Condit. Reinf. lever presses0.20.30.9-0.2-0.60.7-0.6-0.4-0.20.90.8-0.1-0.1
Condit. Reinf. lever reinforcers received0.20.31.2-1.10.2-0.3-0.10.60.7-0.30.10.70.6
Conditioned reinforcement - actives0.30.31.3-0.40.3-0.4-0.40.60.6-1.1-0.50.20.2
Conditioned reinforcement - inactives0.40.51.8-0.0-0.90.7-0.60.1-0.20.51.40.60.8
Conditioned locomotion1.82.14.2-1.41.5-1.31.11.62.0-1.5-0.41.61.6
Patch foraging indifference point 0 sec0.40.61.90.2-1.01.1-0.3-0.7-0.21.40.9-0.1-0.3
Patch foraging indifference point AUC0.20.21.20.0-0.50.2-1.1-0.4-0.10.00.3-0.4-0.0
Delay disc. indifference point, 0s delay0.80.91.8-0.50.9-1.01.21.30.8-0.7-0.11.21.0
Delay disc. indifference point, 16s delay1.51.52.41.5-1.31.0-1.5-1.3-1.31.11.2-1.0-1.1
Delay disc. indifference point, 2s delay0.20.20.40.40.1-0.40.30.6-0.0-0.50.70.60.6
Delay disc. indifference point, 24s delay0.40.41.30.4-0.1-0.3-1.1-0.7-0.2-0.5-0.1-0.9-0.8
Delay disc. indifference point, 4s delay0.30.41.6-0.2-0.50.2-0.20.4-0.10.31.30.70.9
Delay disc. indifference point, 8s delay1.01.02.21.5-1.00.8-1.2-0.7-1.30.61.3-0.5-0.6
Indifference point function ln k0.91.22.4-1.21.4-1.11.61.21.0-0.9-0.90.90.4
Indifference point function log k0.91.22.4-1.21.4-1.11.61.21.0-0.9-0.90.90.4
Patch foraging total patch changes 0 sec0.50.72.20.4-1.21.2-0.5-0.9-0.41.51.0-0.2-0.4
Patch foraging total patch changes 12 sec0.10.10.3-0.3-0.30.20.00.00.40.40.60.30.4
Patch foraging total patch changes 18 sec0.20.30.8-0.1-0.70.5-0.5-0.20.10.80.90.30.4
Patch foraging total patch changes 24 sec0.20.30.70.3-0.80.7-0.6-0.6-0.40.60.5-0.4-0.2
Patch foraging total patch changes 6 sec0.30.51.2-0.4-1.11.0-0.7-0.40.30.90.9-0.10.5
Patch foraging time to switch 0 sec0.10.20.70.50.2-0.10.8-0.1-0.50.3-0.1-0.2-0.5
Patch foraging water rate 0 sec0.20.30.6-0.5-0.70.6-0.6-0.40.30.80.10.00.5
Patch foraging water rate 12 sec0.30.51.10.0-0.81.0-0.8-1.0-0.60.7-0.3-0.7-0.3
Patch foraging water rate 18 sec1.01.43.00.4-1.31.4-1.4-1.7-0.61.50.1-1.3-0.7
Patch foraging water rate 24 sec0.20.31.4-1.20.00.10.2-0.20.60.4-0.40.30.8
Patch foraging water rate 6 sec1.01.52.70.3-1.41.5-1.6-1.2-1.10.7-0.3-1.6-1.4
Seeking ratio, delayed vs. immediate footshock2.93.35.22.2-1.91.7-1.8-2.1-2.02.31.7-1.1-0.9
Distance traveled before self-admin0.60.61.80.6-0.60.30.30.2-0.50.51.31.21.3
Distance traveled after self-admin0.30.30.9-0.8-0.30.30.10.30.80.30.30.81.0
Extensor digitorum longus weight0.10.51.20.4-1.01.1-0.6-0.6-0.60.9-0.0-0.8-0.7
Bone: elastic displacement0.30.31.4-0.70.2-0.10.0-0.00.6-0.5-1.2-0.7-0.5
Bone: elastic work2.33.05.7-2.31.9-1.62.11.62.4-1.3-1.41.21.1
Bone: endosteal estimation1.22.68.1-2.61.4-1.11.11.31.3-1.7-2.8-0.4-0.7
Bone: endosteal perimeter2.04.210.5-2.72.2-1.91.91.91.6-2.5-3.2-0.0-0.6
Epididymis fat weight2.96.811.3-2.23.4-3.42.92.91.9-3.3-2.31.61.1
Delta time in closed arm before/after self-admin1.31.32.7-0.90.9-1.10.51.61.2-1.2-0.21.41.4
Delta time in open arm before/after self-admin0.50.51.20.8-0.30.9-0.2-0.8-0.70.3-0.6-0.9-1.1
Diff in mean of infusions in LGA sessions0.30.30.70.8-0.4-0.1-0.8-0.5-0.30.60.7-0.20.1
Delay discount exponential model param0.40.41.3-0.90.7-0.40.90.20.9-0.1-1.10.20.3
Extinction: sum of active levers before priming0.10.10.20.1-0.10.3-0.3-0.00.30.10.40.20.4
Active lever presses in extinction session 60.20.20.7-0.50.3-0.00.20.40.5-0.1-0.30.50.8
Bone: final force1.62.74.5-1.71.8-2.01.71.52.1-0.90.22.01.6
Bone: final moment1.82.95.1-2.01.8-2.01.71.62.3-1.0-0.02.01.7
Food consumed during 24 hour testing period1.72.03.4-1.31.6-1.61.71.41.8-1.0-0.01.51.4
Glucose0.30.51.20.6-0.80.9-0.1-0.6-0.81.10.7-0.20.0
Heart weight2.33.25.8-2.11.5-1.52.02.12.1-1.0-0.22.42.0
Delay discount hyperbolic model param0.30.31.1-0.70.5-0.30.6-0.00.70.0-1.1-0.00.0
Intermittent access intake day 1-15 change0.40.40.90.6-0.70.7-0.8-0.4-0.40.60.9-0.3-0.4
Intermittent access intake escalation0.50.51.10.7-0.80.7-0.9-0.5-0.60.71.1-0.4-0.5
Intermittent access intake escalation 20.30.20.50.4-0.50.5-0.7-0.2-0.30.40.6-0.4-0.7
Intermitt. access day 1 inactive lever presses0.80.83.1-1.00.2-0.30.90.70.80.30.71.31.8
Intermitt. access day 15 inactive lever presses1.31.46.1-1.1-0.0-0.20.51.10.7-0.00.81.92.5
Intermitt. access escalation Index0.10.10.20.0-0.20.10.00.00.20.40.50.40.2
Intermittent access day 1 total infusions0.80.91.7-1.00.7-0.90.81.01.0-0.9-0.21.21.3
Intermittent access day 15 total infusions0.20.21.00.0-0.30.2-0.40.10.10.21.00.50.5
Intermittent access terminal intake (last 3 days)0.10.10.20.00.1-0.2-0.30.30.2-0.40.40.30.0
Intermittent access total infusions0.30.30.6-0.30.5-0.60.30.50.7-0.40.40.80.6
Intermittent access day 1 locomotion0.40.41.2-0.50.4-0.30.60.80.8-0.40.01.01.1
Intermittent access day 15 total locomotion0.10.10.3-0.20.4-0.40.20.30.6-0.3-0.00.40.3
Intermittent access total locomotion0.50.61.2-0.60.7-0.80.60.60.9-0.40.21.11.1
Intermittent access standard deviation0.70.71.8-0.60.6-0.60.90.91.0-0.30.61.31.0
Left kidney weight11.632.649.1-7.06.3-6.45.66.26.4-5.7-3.44.93.9
Right kidney weight12.234.248.0-6.96.3-6.45.76.56.6-5.9-3.15.44.6
Cocaine induced anxiety1.21.42.6-0.71.5-1.61.50.61.3-0.1-0.11.61.4
Post-drug Anxiety0.50.51.4-0.60.7-0.80.90.21.20.2-0.60.80.7
Baseline Anxiety1.31.42.51.0-1.41.6-1.2-1.0-1.00.60.2-1.5-1.5
Tail length0.20.61.40.4-0.60.6-0.3-0.9-0.90.5-0.2-1.1-1.2
Length with tail0.41.32.6-1.61.4-1.61.10.81.2-1.2-1.00.2-0.5
Length without tail1.12.55.5-1.92.0-2.31.11.51.9-1.6-0.41.30.6
Times rat made contact with spout0.70.81.6-0.70.7-0.80.41.01.3-0.80.41.01.2
Lifetime Intake0.91.02.5-0.70.8-1.00.81.01.1-0.60.61.61.4
Liver weight, left0.81.22.6-1.21.2-1.21.11.00.4-1.6-1.6-0.0-0.6
Liver weight, right2.13.57.2-1.52.4-2.32.12.01.3-2.7-2.00.5-0.5
Locomotor activity2.03.25.8-2.42.0-1.72.01.72.1-1.7-2.10.90.6
Locomotor testing distance0.00.00.1-0.1-0.10.1-0.1-0.2-0.00.1-0.3-0.2-0.4
Locomotor testing rearing1.21.82.9-1.41.5-1.41.41.61.3-1.7-1.11.00.5
Locomotion in novel chamber1.62.04.70.5-1.52.2-1.1-0.8-1.0-0.1-1.4-1.8-2.1
Locomotion in novel chamber post-restriction0.91.12.11.5-1.10.9-1.1-1.0-1.20.80.4-1.1-1.1
Fecal boli incidents, locomotor time 10.20.20.40.6-0.50.3-0.4-0.6-0.20.60.2-0.5-0.1
Change in fecal boli incidents, locomotor task0.50.51.6-0.80.7-0.70.10.30.3-1.3-1.1-0.2-0.8
Time >=10cm from walls, locomotor time 10.10.10.30.10.4-0.60.40.10.2-0.1-0.10.20.0
Bouts of movement, locomotor time 10.40.41.80.21.1-1.30.40.20.5-0.60.10.40.4
Total resting periods, locomotor time 10.30.41.10.60.9-1.00.40.00.3-0.10.70.50.5
Rest time, locomotor task time 10.70.82.00.30.7-0.71.00.70.6-0.11.01.41.4
Distance moved, locomotor task time 10.40.40.8-0.90.6-0.60.30.90.5-0.9-0.90.1-0.0
Vertical activity count, locomotor time 10.00.00.1-0.4-0.10.1-0.20.1-0.20.1-0.1-0.1-0.3
Time >=10cm from walls, locomotor time 20.10.10.30.5-0.30.3-0.1-0.3-0.20.2-0.0-0.4-0.5
Bouts of movement, locomotor time 20.50.61.5-0.10.5-0.51.00.50.7-0.10.71.21.1
Total resting periods, locomotor time 20.50.51.4-0.10.4-0.50.80.40.7-0.00.91.21.1
Rest time, locomotor task time 20.10.10.40.5-0.30.2-0.3-0.3-0.30.30.60.00.2
Distance moved, locomotor task time 20.60.71.6-0.60.8-0.70.81.30.7-1.2-0.70.50.5
Vertical activity count, locomotor time 20.30.30.7-0.60.5-0.40.60.90.6-0.7-0.70.30.2
Light reinforcement 10.30.63.2-1.0-0.30.4-0.20.40.0-0.7-1.8-0.6-0.8
Light reinforcement 20.60.81.3-0.71.1-1.11.01.10.3-1.1-1.10.70.1
Bone: marrow area1.32.88.4-2.81.4-1.11.11.41.4-1.8-2.9-0.4-0.7
Bone: maximum diameter3.87.113.4-3.72.8-2.72.83.02.9-2.7-2.31.81.2
Bone: maximum force2.84.98.1-2.62.3-2.42.32.32.8-1.6-0.62.32.1
Bone: maximum moment3.25.49.0-2.82.4-2.52.42.43.0-1.7-0.82.42.2
Mean time between licks in bursts0.60.91.81.4-1.00.9-0.9-0.8-1.20.80.7-0.5-0.7
Mean num. licks in bursts1.61.92.8-1.31.7-1.71.41.71.4-1.4-0.51.41.1
Cd content in liver0.70.71.7-0.70.8-0.90.81.11.1-1.3-0.70.40.2
Co content in liver0.30.41.0-0.50.4-0.50.50.81.0-0.4-0.40.80.7
Cu content in liver3.64.45.92.0-2.42.4-2.1-2.4-2.42.31.3-1.7-1.5
Fe content in liver0.20.21.1-1.00.00.10.40.20.00.0-0.9-0.3-0.3
K content in liver0.50.51.4-0.0-0.90.9-0.8-0.8-0.31.20.8-0.10.5
Mg content in liver1.11.13.00.4-1.31.2-0.9-1.0-0.61.71.50.00.4
Mn content in liver0.10.20.8-0.20.3-0.3-0.10.5-0.0-0.9-0.6-0.1-0.2
Na content in liver2.42.63.81.8-1.81.9-1.6-1.9-1.71.90.9-1.3-0.9
Rb content in liver0.10.10.2-0.4-0.20.0-0.20.1-0.10.20.50.20.3
Se content in liver0.70.81.40.8-0.90.9-1.0-1.1-1.20.6-0.0-1.2-0.7
Sr content in liver1.00.92.91.7-0.91.0-1.1-0.9-0.90.60.7-0.7-0.3
Zn content in liver1.21.31.80.8-1.31.3-1.2-1.3-1.11.0-0.1-1.3-1.3
Bone: minimum diameter0.71.33.2-1.81.1-1.01.11.00.9-1.3-1.70.1-0.1
Time in familiar zone, hab. session 10.10.10.5-0.10.0-0.3-0.30.2-0.0-0.7-0.1-0.2-0.0
Time in novel zone, hab. session 10.80.81.9-1.00.9-0.51.30.71.1-0.4-1.40.40.1
Total zone transitions, hab. session 13.54.89.31.9-2.52.3-3.1-2.4-2.41.30.5-2.5-2.0
Total locomotion distance, hab. session 12.12.96.60.7-1.71.7-2.3-1.6-1.80.4-0.9-2.6-2.1
Locomotion velocity, hab. session 12.23.16.00.9-1.92.0-2.4-1.8-2.00.8-0.3-2.4-1.8
Time in familiar zone, hab. session 20.30.41.20.70.0-0.00.00.0-0.7-0.7-0.4-0.8-1.1
Time in novel zone, hab. session 20.40.41.3-1.20.1-0.0-0.00.20.90.4-0.00.70.9
Total zone transitions, hab. session 20.81.13.20.5-1.61.3-1.8-0.8-0.90.80.6-0.8-0.4
Total locomotion distance, hab. session 20.60.81.70.6-1.31.3-1.3-0.9-0.80.90.3-0.8-0.2
Locomotion velocity, hab. session 21.21.63.10.9-1.71.7-1.7-1.3-1.21.20.5-1.1-0.4
Novel to familiar place preference ratio2.82.96.0-2.41.9-1.71.71.41.9-1.7-2.20.6-0.2
Novelty place preference3.73.86.9-2.62.2-2.02.01.72.1-2.1-2.40.7-0.2
Time in novel zone, NPP test4.54.68.3-2.92.5-2.22.22.02.4-2.3-2.50.8-0.0
Total zone transitions, NPP test2.84.09.21.6-2.52.2-3.0-2.0-2.01.20.4-2.2-1.6
Total locomotion distance, NPP test1.21.63.60.9-1.51.6-1.9-1.5-1.11.00.3-1.4-0.7
Locomotion velocity, NPP test2.02.84.91.6-2.01.9-2.2-1.9-1.71.30.5-1.8-1.1
Intraocular pressure0.30.41.1-0.30.8-0.70.50.50.4-1.0-0.80.20.2
Delta distance traveled before/after self-admin0.91.03.2-1.70.5-0.4-0.10.51.3-0.9-1.8-0.3-0.2
Delta ambulatory time before/after self-admin1.21.34.4-2.10.5-0.4-0.20.61.6-0.9-2.0-0.3-0.1
Parametrial fat weight0.10.30.70.00.6-0.50.70.70.4-0.30.30.80.7
Pavlov. Cond. lever latency1.01.32.8-1.11.3-1.21.01.01.2-1.3-1.70.5-0.2
Pavlov. Cond. magazine entry latency1.01.34.01.6-1.10.9-1.0-0.8-0.91.22.0-0.00.6
Pavlov. Cond. change in total contacts1.51.65.41.3-1.31.2-1.2-0.9-0.71.42.30.11.0
Pavlov. Cond. index score0.81.04.41.0-0.80.6-0.6-0.4-0.51.02.10.41.1
Pavlov. Cond. latency score0.60.83.70.9-0.80.6-0.5-0.3-0.51.01.90.41.0
Pavlov. Cond. lever contacts1.41.74.01.5-1.41.4-1.1-1.0-1.41.52.0-0.30.5
Pavlov. Cond. magazine entry number0.81.14.4-1.50.9-0.60.80.60.7-0.9-2.1-0.1-0.8
Pavlov. Cond. intertrial magazine entries0.81.01.80.6-1.21.2-1.2-1.3-0.71.30.7-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.91.14.41.3-0.90.7-0.8-0.6-0.81.02.10.20.9
Pavlov. Cond. response bias1.21.45.21.6-1.10.9-0.9-0.7-1.01.22.30.10.8
Pavlov. Cond. lever latency0.70.93.2-0.01.1-1.30.81.10.5-1.8-0.90.50.3
Pavlov. Cond. magazine entry latency3.13.59.21.5-1.91.9-1.6-2.4-1.63.02.3-0.6-0.4
Pavlov. Cond. change in total contacts0.71.04.1-0.5-0.60.7-0.4-0.70.32.01.70.70.6
Pavlov. Cond. index score1.82.47.00.9-1.61.7-1.4-1.8-1.12.71.9-0.5-0.3
Pavlov. Cond. latency score2.32.98.21.1-1.81.8-1.5-2.0-1.22.92.2-0.5-0.2
Pavlov. Cond. lever contacts0.60.93.5-0.0-1.01.3-0.6-1.0-0.41.91.0-0.3-0.2
Pavlov. Cond. magazine entry number1.61.95.7-0.91.3-1.21.21.81.0-2.4-1.90.20.1
Pavlov. Cond. intertrial magazine entries2.53.35.8-1.21.6-1.81.62.42.0-1.8-0.22.12.3
Pavlov. Cond. lever-magazine prob. diff.1.92.47.10.9-1.61.7-1.3-1.9-1.22.71.8-0.6-0.5
Pavlov. Cond. response bias0.81.14.20.1-1.01.2-0.7-1.2-0.42.11.3-0.1-0.1
Time in closed arm before self-admin4.45.09.32.1-2.52.6-1.7-2.5-2.53.11.5-1.7-1.8
Time in closed arm after self-admin0.40.41.2-0.40.5-0.50.81.10.6-0.6-0.20.70.5
Time in open arm before self-admin0.10.20.5-0.00.3-0.5-0.1-0.0-0.0-0.7-0.7-0.5-0.2
Time in open arm after self-admin0.60.71.61.1-0.10.6-0.3-1.0-0.80.1-0.6-1.2-1.3
Bone: periosteal estimation1.73.68.4-2.91.9-1.71.81.81.9-2.0-2.60.40.1
Bone: periosteal perimeter3.65.99.2-3.02.7-2.52.62.52.3-2.8-2.91.00.4
Bone: post-yield work0.40.51.7-0.80.3-0.30.40.71.1-0.20.30.91.3
Progressive ratio test 1 active lever presses0.70.72.2-0.40.6-0.90.20.80.7-0.40.81.21.5
Progressive ratio test 1 breakpoint0.40.51.3-0.10.6-0.9-0.00.60.5-0.40.70.91.1
Progressive ratio test 1 inactive lever presses1.41.55.3-0.30.2-0.40.70.90.60.32.01.92.3
Progressive ratio test 2 active lever presses0.40.42.00.2-0.3-0.1-0.7-0.0-0.00.21.40.71.0
Progressive ratio test 2 breakpoint0.50.52.0-0.0-0.0-0.4-0.50.20.40.21.41.01.4
Progressive ratio test 2 inactive lever presses1.01.13.90.4-1.10.8-0.9-0.2-0.61.12.00.91.4
Incentive Sensitization - Responses0.60.63.10.3-0.70.4-0.8-0.4-0.30.71.80.30.7
Incentive Sensitization - Breakpoint0.50.52.90.2-0.50.2-0.6-0.20.00.51.70.60.9
Sum of active levers in priming session hrs 5-60.00.00.10.3-0.10.10.1-0.1-0.00.40.3-0.00.2
Progressive ratio0.10.10.5-0.1-0.30.4-0.0-0.3-0.40.70.60.10.2
Food seeking constrained by brief footshock1.61.93.0-1.31.4-1.51.71.41.6-1.5-1.01.31.1
Seeking ratio, punishment vs. effort0.70.81.4-0.60.9-1.00.81.01.2-1.2-0.70.80.7
Retroperitoneal fat weight3.712.221.9-2.84.5-4.73.93.93.5-3.7-1.92.82.2
Reaction time number correct1.31.93.71.3-1.11.0-1.9-1.6-1.40.4-0.5-1.9-1.7
Reaction time mean minus median0.10.20.4-0.20.2-0.00.40.50.4-0.6-0.7-0.0-0.6
Reaction time mean minus median AUC0.50.61.6-0.41.0-0.81.30.90.8-1.0-0.60.6-0.1
Reaction time num false alarms0.30.51.7-0.1-0.20.4-0.1-0.1-0.2-0.4-1.2-0.9-1.3
Reaction time num false alarms AUC0.40.61.8-0.1-0.40.6-0.5-0.3-0.5-0.3-1.3-1.1-1.4
Reaction time trials correct on left1.31.93.71.3-1.11.0-1.9-1.6-1.40.4-0.5-1.9-1.7
Reaction time trials on left1.42.14.01.3-1.11.0-1.9-1.7-1.50.4-0.5-2.0-1.8
Reaction time mean0.10.10.30.4-0.40.4-0.3-0.5-0.30.50.1-0.2-0.5
Reaction time mean AUC0.10.10.20.4-0.40.4-0.3-0.5-0.30.50.2-0.2-0.3
Median of all reaction times0.30.30.80.6-0.60.5-0.5-0.8-0.60.90.4-0.2-0.4
Reaction time omissions0.40.51.00.8-0.70.7-0.9-0.6-0.80.2-0.2-0.9-1.0
Reaction time false alarm rate0.10.20.5-0.50.10.10.60.60.2-0.4-0.70.1-0.2
Reaction time premature initiation rate0.20.31.5-0.6-0.50.4-0.2-0.50.31.20.50.20.4
Reaction time premature initiations0.30.41.3-0.0-0.70.5-0.9-1.0-0.21.10.3-0.5-0.3
Std. dev. reaction times0.20.30.7-0.70.5-0.20.60.70.6-0.7-0.80.3-0.3
Reaction time trials completed1.42.14.01.3-1.11.0-1.9-1.7-1.50.4-0.5-2.0-1.8
Reaction time trials AUC1.11.63.31.1-0.90.8-1.7-1.5-1.30.4-0.6-1.8-1.6
Run reversals in cocaine runway, females1.11.12.30.9-0.90.9-1.1-0.8-1.30.0-0.7-1.5-1.5
Run reversals in cocaine runway, males0.50.51.8-0.90.5-0.6-0.20.30.4-1.4-1.2-0.2-0.1
Latency to leave start box in cocaine runway0.30.30.9-0.10.9-0.80.80.60.6-0.3-0.10.40.3
Latency to leave start box in cocaine runway, F0.20.20.30.5-0.30.4-0.4-0.5-0.50.50.1-0.6-0.5
Latency to leave start box in cocaine runway, M2.42.33.7-0.91.9-1.81.91.61.7-1.1-0.11.71.5
Std. dev. time between licks in bursts1.21.42.70.6-1.61.5-1.5-1.2-0.91.61.1-0.5-0.1
Total sessions with >9 infusions1.71.93.2-1.21.3-1.61.01.51.7-1.10.11.81.6
Short access day 1 total inactive lever presses1.31.43.3-1.80.7-0.60.81.41.5-0.7-0.61.51.5
Short access day 10 total inactive lever presses0.50.61.4-1.20.3-0.10.80.60.7-0.7-1.10.50.8
Short access day 1 total infusions1.71.83.8-1.50.8-1.01.11.71.4-1.00.02.01.7
Short access day 10 total infusions1.11.22.3-0.41.3-1.51.10.91.3-0.50.41.41.3
Short access total infusions2.62.96.4-1.21.4-1.71.61.91.9-1.00.52.52.3
Short access day 1 locomotion0.30.31.2-0.00.2-0.40.50.70.3-0.00.41.11.0
Short access day 10 total locomotion0.20.30.60.5-0.30.70.70.2-0.10.30.40.70.8
Short access total locomotion1.51.63.7-0.51.0-1.01.41.41.4-0.70.31.91.9
One hour access (0.3 mA shock)0.40.41.21.1-0.70.7-0.8-0.6-0.40.40.8-0.2-0.4
Compulsive drug intake2.02.14.21.1-1.71.5-2.0-1.7-1.11.10.6-1.5-1.3
One hour access (shock baseline)0.20.20.40.50.6-0.50.50.40.1-0.30.60.50.3
Social response proportion0.30.40.9-0.20.3-0.11.00.50.70.60.40.90.4
Social responses0.10.10.4-0.1-0.40.4-0.3-0.0-0.1-0.0-0.4-0.6-0.6
Social time1.72.23.51.9-1.71.7-1.5-1.4-1.41.61.7-0.9-0.4
Soleus weight0.20.41.40.0-1.00.9-1.2-0.4-0.10.50.7-0.10.4
Bone: stiffness1.72.73.8-1.71.7-1.71.91.82.0-1.0-0.41.91.7
Tibialis anterior weight0.51.93.21.6-1.71.6-1.4-1.5-1.11.81.3-0.5-0.2
Time to tail flick, vehicle, before self-admin0.20.20.6-0.60.0-0.2-0.20.10.2-0.3-0.8-0.6-0.4
Time to tail flick, vehicle, after self-admin1.51.64.40.7-0.81.0-0.9-1.3-1.20.2-1.2-2.1-2.0
Time to tail flick, test, before self-admin0.30.31.30.10.0-0.30.20.2-0.4-0.9-1.2-0.7-0.4
Time to tail flick, test, after self-admin1.11.21.91.2-1.11.2-0.7-1.0-1.30.90.5-1.1-1.4
Delta time to tail flick, vehicle, before/after SA0.10.10.30.3-0.20.40.1-0.6-0.30.60.2-0.1-0.1
Delta time to tail flick, test, before/after SA2.52.33.61.2-1.71.9-1.6-1.4-1.51.71.2-1.1-1.4
Tibia length0.71.94.7-2.21.5-1.71.11.31.7-1.4-0.71.10.4
Ambulatory time before self-admin0.70.72.30.6-0.90.70.10.1-0.80.41.50.91.2
Ambulatory time after self-admin0.40.51.5-0.3-1.21.2-0.8-0.6-0.10.7-0.1-0.3-0.0
Bone: tissue strength0.20.20.7-0.90.3-0.40.30.10.6-0.1-0.30.20.2
Total heroin consumption0.10.10.4-0.4-0.10.0-0.20.00.60.10.20.40.7
Bone: trabecular number0.10.20.60.30.2-0.20.3-0.2-0.2-0.3-0.7-0.4-0.8
Bone: trabecular spacing1.11.52.3-1.01.2-1.31.11.31.5-1.00.31.41.5
Bone: trabecular thickness0.20.20.50.3-0.40.5-0.1-0.4-0.70.6-0.4-0.3-0.4
Bone: trabecular tissue density1.11.54.30.9-1.51.5-1.1-1.4-0.82.10.9-0.6-0.3
Water consumed over 24 hours0.70.82.1-1.20.8-0.90.81.01.4-0.9-0.50.70.6
Number of responses in last shaping day1.21.24.70.9-1.21.0-0.8-0.3-0.71.52.20.50.7