Hub : Genes

Snf8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA isoform ratio NM_001007804.2 0.2 0.13 7.1e-09 0.13 0.14 0.13 0.14 1.8e-07 4.9e-08 2.4e-07 5.9e-08
2 Liver gene expression Snf8 0.04 0.03 2.4e-05 0.05 0.04 0.05 0.05 4.6e-06 2.6e-05 6.7e-06 4.0e-06
3 PL isoform ratio XM_039085602.1 0.06 0.05 1.6e-07 0.06 0.06 0.06 0.06 1.6e-07 1.9e-07 4.3e-07 4.6e-07
4 Liver isoform ratio XM_039085602.1 0.13 0.07 0.0e+00 0.17 0.15 0.17 0.01 6.3e-19 2.5e-16 3.9e-18 6.3e-02
5 BLA mRNA stability Snf8 0.09 0.09 1.4e-03 0.04 0.04 0.02 0.04 2.3e-03 2.6e-03 3.1e-02 3.5e-03
6 pVTA intron excision ratio chr10_80984820_80990408 0.08 0.06 7.1e-04 0.03 0 -0 -0 1.6e-02 2.8e-01 6.2e-01 5.2e-01
7 PL mRNA stability Snf8 0.02 0.02 5.8e-03 0.02 0.02 0.02 0.02 1.4e-03 3.9e-03 1.8e-03 3.4e-03
8 NAcc isoform ratio XM_039085602.1 0.06 0.03 5.7e-11 0.09 0.09 0.08 0.08 1.3e-10 1.4e-10 2.2e-09 1.4e-09
9 Adipose gene expression Snf8 0.03 0.03 1.2e-03 0.02 0.01 0.02 0.02 2.9e-03 1.0e-02 2.6e-03 2.8e-03
10 Adipose intron excision ratio chr10_80984820_80990408 0.02 0.01 4.0e-03 0.01 0.01 0 0 6.6e-02 2.6e-02 2.4e-01 9.7e-02
11 Brain isoform ratio NM_001007804.2 0.05 0.03 1.3e-06 0.05 0.06 0.05 0.05 3.4e-05 4.0e-06 3.5e-05 3.2e-05
12 NAcc isoform ratio NM_001007804.2 0.03 0.02 5.5e-04 0.02 0.03 0.02 0.02 3.2e-03 4.3e-04 2.4e-03 3.5e-03
13 PL intron excision ratio chr10_80984820_80990408 0.11 0.06 2.2e-08 0.06 0.07 0.05 0.06 5.0e-07 7.5e-08 1.6e-06 1.8e-07
14 Brain intron excision ratio chr10_80984820_80990408 0.1 0.06 2.8e-10 0.1 0.1 0.1 0.1 1.0e-09 6.3e-10 1.1e-09 2.0e-09
15 Liver isoform ratio NM_001007804.2 0.13 0.07 0.0e+00 0.16 0.16 0.16 0.16 1.3e-17 1.4e-17 1.1e-17 1.5e-17
16 PL isoform ratio NM_001007804.2 0.07 0.05 8.1e-07 0.05 0.05 0.05 0.05 3.6e-06 1.2e-06 5.2e-06 7.3e-06
17 pVTA isoform ratio NM_001007804.2 0.09 0.09 3.2e-03 0.04 0.01 0 0.01 6.1e-03 1.1e-01 2.4e-01 9.7e-02
18 Liver intron excision ratio chr10_80984820_80990408 0.15 0.08 1.3e-11 0.11 0.11 0.1 0.12 1.7e-12 1.4e-12 1.4e-11 5.3e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density1.21.93.01.41.51.21.51.2-1.51.31.5-0.71.31.41.41.71.3-1.71.5-0.61.7
Area under the delay curve0.10.10.2-0.2-0.0-0.2-0.0-0.0-0.1-0.1-0.3-0.3-0.1-0.2-0.2-0.5-0.10.1-0.2-0.4-0.4
BMI with tail16.252.675.78.17.67.17.67.1-7.87.18.3-5.77.47.47.58.77.0-7.77.0-3.36.5
BMI without tail0.91.84.41.61.31.01.21.2-1.31.01.8-0.31.31.31.42.11.1-1.61.20.11.6
Body weight0.93.75.42.02.21.72.11.7-2.31.72.0-1.82.02.01.91.91.9-2.12.0-1.61.5
Weight adjusted by age0.20.21.3-0.3-0.1-0.2-0.1-0.20.1-0.2-0.5-0.5-0.3-0.4-0.5-0.7-0.40.7-0.5-0.0-1.2
Bone surface0.40.71.00.70.90.60.90.6-1.00.60.9-0.50.80.80.80.80.8-1.01.0-0.91.0
Bone volume1.01.72.61.21.31.01.31.0-1.41.11.4-0.81.31.31.31.31.4-1.51.6-1.31.6
Breakpoint value in progressive ratio session3.23.54.4-1.7-1.9-2.0-1.9-2.01.9-1.5-2.01.8-1.8-1.8-1.8-1.9-1.82.1-2.01.6-2.1
Number of licking bursts0.81.01.9-1.0-1.0-1.1-1.0-1.01.0-1.2-0.91.2-1.1-1.0-1.0-0.3-1.10.8-0.91.4-0.4
Context. condit. distance diff. score0.91.11.61.21.21.11.21.2-1.31.00.9-1.31.01.01.01.01.0-0.90.9-0.50.4
Locomotion velocity, session 10.10.10.6-0.1-0.2-0.1-0.2-0.10.1-0.10.00.8-0.2-0.1-0.00.4-0.1-0.20.00.80.6
Locomotion distance, session 14.55.76.7-2.6-2.6-2.6-2.6-2.62.5-2.5-2.42.6-2.5-2.4-2.4-2.2-2.42.2-2.31.9-1.7
Locomotion velocity, session 21.11.32.6-1.4-1.3-1.2-1.3-1.21.2-1.1-1.20.7-1.1-1.1-1.1-1.6-1.01.2-1.0-0.1-0.9
Locomotion distance, session 26.18.510.2-3.0-3.1-3.1-3.1-3.23.0-2.9-3.03.2-3.0-3.0-2.9-2.5-2.92.8-2.92.7-2.0
Locomotion velocity, session 30.40.52.10.60.60.70.60.7-0.70.70.4-1.00.80.70.6-0.10.7-0.40.6-1.40.0
Locomotion distance, session 31.61.73.3-1.2-1.2-1.2-1.2-1.21.1-1.1-1.60.6-1.2-1.3-1.4-1.6-1.31.5-1.50.7-1.8
Stereotopy head waving bouts, day 34.04.85.62.32.02.12.12.2-2.32.22.2-1.32.32.32.42.22.3-2.32.3-1.82.4
Stereotopy head waving duration, day 33.23.84.31.91.91.91.92.0-2.11.92.1-1.42.02.02.01.82.1-2.12.1-1.82.1
Locomotion velocity, session 71.11.21.7-1.2-1.1-1.3-1.1-1.21.1-1.3-1.10.7-1.0-1.0-1.1-1.3-1.01.1-0.90.3-1.2
Locomotion distance, session 76.07.69.9-3.0-2.8-3.1-2.8-3.12.6-3.1-2.72.3-2.8-2.8-2.9-2.7-2.82.6-2.62.0-2.5
Stereotopy head waving bouts, day 70.40.40.80.70.50.70.50.7-0.60.80.5-0.00.70.70.80.70.7-0.70.7-0.40.9
Stereotopy head waving duration, day 70.20.30.50.60.40.70.30.6-0.40.70.4-0.10.60.60.60.40.7-0.50.6-0.60.6
Locomotion velocity, session 80.50.61.11.00.80.90.91.0-0.61.10.5-0.80.90.90.90.80.9-0.40.7-0.50.3
Locomotion distance, session 80.60.81.4-0.8-0.8-0.9-0.8-0.80.8-0.8-1.10.8-0.9-1.0-0.9-0.8-1.01.0-1.01.2-1.0
Degree of sensitization distance0.10.10.4-0.5-0.3-0.6-0.3-0.60.3-0.6-0.10.2-0.4-0.3-0.3-0.2-0.30.1-0.10.2-0.0
Degree of sensitization stereotypy0.20.30.9-0.4-0.6-0.4-0.6-0.50.5-0.4-0.50.9-0.5-0.4-0.4-0.2-0.50.5-0.50.9-0.1
Conditioned locomotion1.92.34.71.41.71.71.71.7-1.51.51.5-2.21.41.41.41.31.4-1.41.4-1.01.1
Cocaine response after cond. corrected5.76.48.62.82.52.62.62.6-2.52.62.9-1.92.52.52.62.92.4-2.72.4-1.22.5
Cocaine response after cond. not corrected3.23.64.92.12.02.02.02.0-1.92.02.2-1.51.91.91.92.21.8-2.01.7-0.91.8
Cocaine response before conditioning2.63.24.1-1.9-1.8-1.9-1.8-1.81.9-1.8-2.01.5-1.8-1.8-1.9-2.0-1.81.8-1.81.0-1.6
Saline control response0.20.21.40.30.40.40.40.4-0.40.30.6-0.80.1-0.00.00.6-0.2-0.2-0.01.2-0.3
Bone: connectivity density0.20.30.70.70.70.50.80.5-0.80.50.5-0.40.50.50.60.70.5-0.70.5-0.30.5
Bone: cortical apparent density5.06.710.4-2.6-2.8-2.5-2.7-2.52.7-2.6-2.71.7-2.5-2.5-2.6-2.9-2.52.9-2.51.2-3.2
Bone: cortical area0.40.61.10.60.90.60.80.6-0.90.71.0-1.10.70.70.60.50.7-0.80.7-0.70.4
Bone: cortical porosity0.30.40.60.60.60.50.70.5-0.60.50.8-0.50.60.60.60.60.5-0.80.6-0.50.7
Bone: cortical porosity0.20.20.40.40.40.30.50.3-0.50.40.6-0.30.40.40.40.50.4-0.70.5-0.40.6
Bone: cortical thickness0.20.31.70.40.60.40.50.4-0.50.50.6-1.30.50.40.3-0.10.4-0.10.3-0.9-0.5
Bone: cortical thickness0.60.61.4-0.7-0.6-0.7-0.6-0.70.6-0.7-1.10.3-0.8-0.8-0.9-1.2-0.80.9-1.10.3-1.1
Bone: cortical tissue density5.67.311.0-2.7-2.9-2.7-2.8-2.72.8-2.7-2.91.9-2.6-2.7-2.8-3.0-2.63.1-2.61.3-3.3
Condit. Reinf. active minus inactive responses0.91.01.8-1.0-1.1-1.2-1.1-1.21.1-1.4-0.61.3-1.0-1.0-1.0-0.6-1.00.8-0.90.8-0.4
Condit. Reinf. active-inactive response ratio0.00.10.30.20.2-0.00.2-0.0-0.1-0.00.50.10.10.10.20.40.1-0.30.10.20.5
Condit. Reinf. active responses1.11.32.8-1.2-1.4-1.3-1.4-1.31.2-1.4-0.91.7-1.2-1.1-1.0-0.7-1.10.9-1.01.0-0.2
Condit. Reinf. inactive responses1.11.32.3-1.2-1.4-0.9-1.4-0.91.1-1.1-1.31.5-1.2-1.1-1.1-0.8-1.11.0-1.01.2-0.6
Incentive salience index mean1.82.23.3-1.5-1.6-1.6-1.6-1.61.6-1.7-1.21.8-1.5-1.5-1.4-1.0-1.51.2-1.41.5-0.6
Condit. Reinf. lever presses2.53.34.8-1.8-1.9-1.8-1.9-1.81.9-1.8-1.82.1-1.9-1.9-1.8-1.3-1.91.6-1.82.2-1.2
Condit. Reinf. active minus inactive responses0.20.31.5-0.4-0.5-0.4-0.5-0.40.3-0.5-0.21.1-0.5-0.4-0.30.3-0.5-0.1-0.31.20.4
Condit. Reinf. active-inactive response ratio0.40.53.3-0.2-0.4-0.5-0.4-0.40.3-0.6-0.11.3-0.5-0.5-0.30.7-0.6-0.1-0.41.80.6
Condit. Reinf. active responses0.10.10.5-0.4-0.4-0.4-0.4-0.30.2-0.5-0.30.7-0.4-0.4-0.3-0.1-0.4-0.0-0.30.70.1
Condit. Reinf. inactive responses0.00.10.3-0.10.10.1-0.00.1-0.00.0-0.2-0.40.10.0-0.1-0.50.00.10.0-0.5-0.4
Condit. Reinf. lever presses0.50.61.8-0.9-0.6-0.5-0.7-0.50.7-0.6-1.10.2-0.7-0.8-0.9-1.4-0.70.9-0.8-0.1-1.1
Condit. Reinf. lever reinforcers received0.10.20.5-0.4-0.4-0.4-0.4-0.40.3-0.5-0.40.6-0.4-0.4-0.4-0.2-0.50.1-0.40.7-0.1
Conditioned reinforcement - actives0.30.32.1-0.3-0.5-0.5-0.5-0.50.2-0.60.01.5-0.4-0.2-0.20.4-0.3-0.3-0.00.70.9
Conditioned reinforcement - inactives0.10.10.2-0.30.0-0.30.0-0.3-0.1-0.40.3-0.0-0.3-0.3-0.3-0.1-0.4-0.1-0.20.5-0.4
Conditioned locomotion0.40.53.50.40.20.50.20.5-0.40.40.40.80.40.50.61.10.4-1.10.70.61.9
Patch foraging indifference point 0 sec1.32.13.31.41.71.71.71.8-1.61.60.9-1.81.41.41.41.01.4-1.21.2-1.41.2
Patch foraging indifference point AUC0.10.10.2-0.3-0.0-0.0-0.0-0.10.2-0.4-0.4-0.0-0.2-0.2-0.3-0.4-0.20.3-0.30.1-0.3
Delay disc. indifference point, 0s delay0.20.21.5-0.10.30.10.20.2-0.20.2-0.3-1.2-0.1-0.1-0.2-0.5-0.10.2-0.1-0.5-0.8
Delay disc. indifference point, 16s delay0.91.01.31.11.01.01.01.1-1.11.00.9-1.01.11.01.00.61.0-0.90.8-1.00.6
Delay disc. indifference point, 2s delay0.10.10.3-0.5-0.0-0.3-0.0-0.00.0-0.2-0.4-0.4-0.3-0.3-0.3-0.5-0.20.2-0.1-0.3-0.4
Delay disc. indifference point, 24s delay0.80.81.3-0.9-0.9-1.1-0.8-1.10.8-0.9-0.80.9-0.9-0.9-0.9-0.9-0.90.8-0.90.5-0.7
Delay disc. indifference point, 4s delay1.31.33.4-1.3-0.9-1.2-0.9-1.00.8-0.9-1.5-0.0-1.1-1.1-1.3-1.8-1.01.3-1.1-0.4-1.8
Delay disc. indifference point, 8s delay0.10.10.2-0.3-0.3-0.4-0.2-0.20.1-0.4-0.40.1-0.3-0.3-0.3-0.5-0.30.3-0.4-0.2-0.3
Indifference point function ln k0.00.00.1-0.1-0.3-0.2-0.3-0.30.20.0-0.20.2-0.2-0.2-0.2-0.2-0.20.2-0.30.2-0.2
Indifference point function log k0.00.00.1-0.1-0.3-0.2-0.3-0.30.20.0-0.20.2-0.2-0.2-0.2-0.2-0.20.2-0.30.2-0.2
Patch foraging total patch changes 0 sec1.52.44.01.51.81.81.81.9-1.71.71.1-2.01.51.51.51.01.5-1.31.4-1.51.2
Patch foraging total patch changes 12 sec0.10.10.30.10.50.50.50.5-0.50.0-0.0-0.50.10.20.20.20.1-0.30.30.00.4
Patch foraging total patch changes 18 sec2.33.04.21.72.01.92.02.1-1.81.81.4-2.01.71.71.61.31.7-1.71.6-1.61.5
Patch foraging total patch changes 24 sec1.21.42.81.21.41.41.41.4-1.21.10.8-0.91.11.21.21.11.2-1.31.1-0.71.7
Patch foraging total patch changes 6 sec1.01.52.41.21.51.41.51.5-1.40.90.9-1.41.21.21.21.01.1-1.11.1-1.01.0
Patch foraging time to switch 0 sec0.10.10.3-0.3-0.3-0.3-0.3-0.20.3-0.4-0.40.4-0.4-0.3-0.20.0-0.30.1-0.20.50.3
Patch foraging water rate 0 sec1.62.63.31.81.71.61.71.7-1.81.61.8-1.41.71.71.71.41.6-1.51.5-1.41.1
Patch foraging water rate 12 sec0.40.71.20.90.90.80.90.8-1.01.00.9-1.10.90.80.70.30.8-0.50.6-1.0-0.4
Patch foraging water rate 18 sec0.00.10.50.10.1-0.00.10.0-0.2-0.10.3-0.40.0-0.0-0.1-0.1-0.10.3-0.10.2-0.7
Patch foraging water rate 24 sec1.31.82.61.51.51.31.51.4-1.51.51.6-1.41.41.41.41.31.3-1.21.3-0.90.9
Patch foraging water rate 6 sec0.10.10.50.50.20.20.20.2-0.40.40.00.40.20.10.20.50.1-0.2-0.20.70.0
Seeking ratio, delayed vs. immediate footshock1.71.93.81.31.41.71.41.6-1.41.41.6-1.91.41.31.31.01.3-1.31.4-1.30.6
Distance traveled before self-admin2.62.77.0-1.6-1.4-1.8-1.4-1.81.3-1.8-1.62.2-1.8-1.7-1.6-0.8-1.81.1-1.62.7-0.7
Distance traveled after self-admin0.20.20.90.60.50.20.50.3-0.50.3-0.00.40.30.30.40.90.2-0.70.10.40.9
Extensor digitorum longus weight0.83.15.51.91.81.91.71.8-1.91.71.8-2.31.91.81.71.21.8-1.41.6-2.10.5
Bone: elastic displacement0.00.00.10.20.20.10.20.1-0.20.1-0.00.00.10.10.10.40.1-0.10.10.30.3
Bone: elastic work0.00.00.00.00.20.20.20.2-0.20.10.0-0.1-0.0-0.0-0.00.1-0.1-0.00.00.1-0.0
Bone: endosteal estimation0.10.11.00.10.30.10.30.2-0.30.10.30.40.10.20.20.40.2-0.70.40.01.0
Bone: endosteal perimeter0.20.41.60.40.70.40.60.5-0.60.50.7-0.10.50.60.60.70.6-0.90.7-0.21.3
Epididymis fat weight0.10.20.50.40.50.00.50.1-0.70.20.7-0.20.40.40.30.60.2-0.60.40.10.1
Delta time in closed arm before/after self-admin0.20.21.50.20.30.20.30.2-0.20.30.4-1.00.40.30.2-0.10.3-0.10.4-1.2-0.4
Delta time in open arm before/after self-admin0.00.00.1-0.10.10.00.10.1-0.1-0.0-0.1-0.3-0.1-0.1-0.1-0.2-0.10.3-0.10.2-0.2
Diff in mean of infusions in LGA sessions1.61.83.9-1.2-1.3-1.7-1.3-1.71.4-1.1-1.02.0-1.3-1.3-1.2-0.7-1.31.0-1.21.7-0.5
Delay discount exponential model param0.10.10.40.30.20.40.10.2-0.00.20.40.10.30.30.30.60.3-0.30.40.30.5
Extinction: sum of active levers before priming1.11.11.8-1.3-0.8-1.1-0.8-1.20.8-1.3-0.90.2-1.1-1.1-1.2-1.4-1.01.0-0.90.2-1.3
Active lever presses in extinction session 60.00.00.10.30.10.10.10.1-0.10.2-0.10.20.20.20.20.20.2-0.2-0.0-0.30.4
Bone: final force0.10.20.60.30.50.20.50.2-0.50.30.8-0.00.30.30.40.70.3-0.70.50.20.8
Bone: final moment0.20.30.80.50.60.40.60.4-0.70.50.9-0.20.50.50.50.80.4-0.80.60.10.9
Food consumed during 24 hour testing period1.92.33.0-1.6-1.6-1.6-1.6-1.61.6-1.6-1.71.3-1.5-1.5-1.6-1.5-1.51.7-1.51.0-1.4
Glucose1.01.53.11.11.21.11.21.2-1.21.11.2-1.31.31.31.20.91.3-1.11.4-1.70.9
Heart weight1.41.93.41.21.41.01.30.9-1.50.81.8-0.71.31.41.41.61.4-1.71.7-1.11.9
Delay discount hyperbolic model param0.20.20.60.40.20.50.20.2-0.10.30.50.20.40.40.50.80.4-0.40.40.40.7
Intermittent access intake day 1-15 change1.11.12.71.01.11.01.11.0-1.10.90.7-0.40.91.01.11.31.0-1.21.0-0.41.7
Intermittent access intake escalation0.70.62.90.70.80.70.80.7-0.80.60.30.10.60.70.81.00.8-1.00.7-0.41.7
Intermittent access intake escalation 20.90.92.60.91.01.01.01.0-0.90.90.4-0.30.70.80.91.30.8-1.00.7-0.21.6
Intermitt. access day 1 inactive lever presses0.10.10.60.2-0.0-0.1-0.0-0.1-0.0-0.00.40.2-0.0-0.00.00.5-0.1-0.2-0.10.8-0.1
Intermitt. access day 15 inactive lever presses1.61.72.61.31.41.41.41.4-1.41.31.4-1.61.31.31.30.91.3-1.31.2-1.50.8
Intermitt. access escalation Index0.20.21.6-0.3-0.4-0.3-0.4-0.30.3-0.2-0.41.3-0.3-0.2-0.10.1-0.20.0-0.10.61.0
Intermittent access day 1 total infusions0.80.91.5-1.1-1.2-1.2-1.2-1.21.1-1.2-0.40.9-0.9-0.9-1.0-0.9-0.90.8-0.60.2-0.9
Intermittent access day 15 total infusions0.30.41.3-0.7-0.6-0.7-0.6-0.70.7-0.9-0.51.1-0.7-0.6-0.5-0.2-0.60.2-0.30.50.3
Intermittent access terminal intake (last 3 days)0.10.10.5-0.4-0.3-0.4-0.3-0.40.3-0.6-0.10.7-0.4-0.3-0.30.1-0.3-0.0-0.10.30.3
Intermittent access total infusions0.10.20.5-0.6-0.4-0.6-0.4-0.60.3-0.7-0.00.5-0.4-0.4-0.4-0.3-0.40.1-0.10.2-0.2
Intermittent access day 1 locomotion2.02.13.2-1.6-1.8-1.7-1.8-1.71.6-1.7-1.31.8-1.4-1.4-1.4-1.2-1.31.2-1.00.7-0.6
Intermittent access day 15 total locomotion0.40.41.4-0.8-0.6-0.9-0.6-0.90.5-0.9-0.61.2-0.6-0.5-0.5-0.2-0.50.1-0.20.30.6
Intermittent access total locomotion0.60.72.5-1.0-0.9-1.0-0.9-1.00.7-1.1-0.61.6-0.8-0.7-0.6-0.3-0.60.1-0.30.50.7
Intermittent access standard deviation1.11.13.40.91.10.91.10.9-1.10.90.8-0.40.91.01.01.21.0-1.41.1-0.71.9
Left kidney weight0.00.11.2-0.10.1-0.00.0-0.1-0.2-0.10.0-0.20.10.10.1-0.40.2-0.10.3-1.10.0
Right kidney weight0.61.64.01.01.21.41.21.3-1.31.31.0-1.31.31.31.20.51.4-1.11.5-2.01.0
Cocaine induced anxiety0.10.11.60.10.10.10.10.1-0.30.10.10.4-0.1-0.00.00.5-0.1-0.30.01.30.3
Post-drug Anxiety1.01.13.8-1.0-0.9-1.1-0.9-1.10.9-1.1-0.71.2-1.1-1.1-1.0-0.3-1.20.8-0.92.0-0.6
Baseline Anxiety0.00.00.20.00.2-0.10.2-0.10.0-0.10.2-0.30.10.10.1-0.00.10.10.1-0.50.0
Tail length15.446.761.7-7.6-7.1-7.1-7.2-7.07.2-7.1-7.55.8-7.0-6.9-7.1-7.9-6.77.0-6.53.3-5.9
Length with tail7.527.346.9-6.0-5.3-5.4-5.3-5.55.2-5.4-6.03.6-5.2-5.2-5.4-6.9-4.95.5-4.80.9-5.0
Length without tail0.10.21.7-0.20.2-0.00.3-0.2-0.40.0-0.2-0.80.10.1-0.0-0.70.20.10.3-1.3-0.6
Times rat made contact with spout0.60.71.0-0.9-1.0-0.9-1.0-1.01.0-0.9-0.61.0-0.8-0.8-0.8-0.6-0.80.7-0.60.5-0.4
Lifetime Intake0.20.30.5-0.6-0.6-0.6-0.6-0.60.5-0.7-0.50.6-0.5-0.5-0.5-0.5-0.50.4-0.40.3-0.4
Liver weight, left0.91.41.9-1.3-1.2-1.4-1.3-1.41.2-1.3-1.11.2-1.2-1.2-1.2-1.3-1.11.1-1.10.7-1.0
Liver weight, right0.50.82.0-1.1-0.7-1.2-0.7-1.20.6-1.1-0.80.2-0.8-0.8-0.9-1.4-0.80.8-0.6-0.8-1.1
Locomotor activity0.20.31.40.70.50.30.50.3-0.60.30.40.50.40.40.51.20.3-0.70.21.00.9
Locomotor testing distance0.50.82.71.01.00.71.00.8-1.00.60.40.10.60.60.71.60.5-1.00.41.41.2
Locomotor testing rearing0.20.31.90.50.50.30.60.3-0.60.1-0.10.10.10.10.20.9-0.0-0.4-0.11.40.4
Locomotion in novel chamber0.20.21.0-0.3-0.1-0.5-0.1-0.40.1-0.5-0.30.0-0.5-0.5-0.50.1-0.60.3-0.41.0-0.9
Locomotion in novel chamber post-restriction1.51.82.91.11.71.11.71.1-1.61.11.7-1.71.11.11.11.61.1-1.51.4-0.51.2
Fecal boli incidents, locomotor time 12.93.24.22.01.81.61.61.6-1.61.71.7-1.02.02.02.12.02.0-1.81.9-1.62.0
Change in fecal boli incidents, locomotor task1.91.83.0-1.5-1.4-1.5-1.2-1.41.1-1.5-1.00.8-1.4-1.5-1.5-1.4-1.51.4-1.30.9-1.7
Time >=10cm from walls, locomotor time 10.20.21.3-0.1-0.0-0.1-0.10.00.0-0.30.10.0-0.4-0.4-0.40.1-0.50.2-0.51.2-0.6
Bouts of movement, locomotor time 10.20.31.00.40.30.40.50.3-0.70.50.1-0.50.60.60.50.10.6-0.50.6-1.00.2
Total resting periods, locomotor time 10.60.61.50.70.60.70.80.6-0.90.80.5-0.80.90.90.80.40.9-0.70.9-1.20.4
Rest time, locomotor task time 10.10.10.40.30.30.40.50.3-0.20.40.0-0.30.40.40.40.20.5-0.30.5-0.60.5
Distance moved, locomotor task time 12.32.54.7-1.5-1.5-1.8-1.8-1.61.5-1.7-1.11.8-1.7-1.6-1.6-1.1-1.71.4-1.62.2-1.1
Vertical activity count, locomotor time 10.60.62.1-0.6-0.6-0.9-0.8-0.60.6-0.9-0.30.7-0.8-0.8-0.8-0.3-0.90.7-0.91.5-0.8
Time >=10cm from walls, locomotor time 20.40.40.7-0.5-0.5-0.7-0.5-0.50.6-0.7-0.40.2-0.7-0.7-0.7-0.5-0.80.7-0.80.7-0.8
Bouts of movement, locomotor time 20.10.10.20.10.40.30.40.3-0.3-0.10.2-0.20.10.10.20.40.1-0.40.30.30.4
Total resting periods, locomotor time 20.10.10.30.20.50.40.40.4-0.4-0.10.2-0.30.10.20.20.60.1-0.40.40.50.4
Rest time, locomotor task time 20.50.51.3-0.7-0.8-0.5-0.9-0.70.9-0.3-0.90.3-0.6-0.7-0.7-0.9-0.61.0-0.70.3-1.1
Distance moved, locomotor task time 20.20.20.6-0.5-0.4-0.6-0.5-0.40.4-0.8-0.40.3-0.4-0.4-0.4-0.6-0.40.4-0.4-0.2-0.4
Vertical activity count, locomotor time 20.10.10.7-0.3-0.1-0.6-0.2-0.20.1-0.8-0.20.2-0.3-0.3-0.3-0.2-0.30.1-0.2-0.0-0.1
Light reinforcement 10.10.20.80.30.20.20.20.2-0.10.1-0.10.60.10.10.20.80.1-0.40.00.90.8
Light reinforcement 20.40.51.3-0.7-0.7-0.7-0.7-0.70.8-0.6-1.01.1-0.8-0.7-0.6-0.2-0.70.5-0.71.10.1
Bone: marrow area0.00.10.7-0.00.20.00.20.1-0.20.00.20.50.00.10.10.20.1-0.50.30.10.8
Bone: maximum diameter0.30.51.40.60.80.50.80.6-0.80.60.9-0.30.60.60.70.80.7-1.00.7-0.21.2
Bone: maximum force0.61.01.80.91.10.91.20.9-1.21.01.3-0.81.01.01.01.00.9-1.21.1-0.71.1
Bone: maximum moment0.71.21.81.01.21.01.31.0-1.31.11.3-0.91.11.11.11.01.1-1.31.2-0.81.2
Mean time between licks in bursts0.91.33.30.91.11.11.11.1-1.11.11.3-1.81.21.11.00.61.1-1.01.2-1.50.3
Mean num. licks in bursts0.10.11.10.10.20.30.20.1-0.20.40.3-0.60.30.30.2-0.40.3-0.00.3-1.0-0.2
Cd content in liver0.40.44.0-0.2-0.2-0.3-0.2-0.30.2-0.4-0.00.3-0.6-0.6-0.50.3-0.80.4-0.72.0-0.8
Co content in liver0.10.10.40.20.00.1-0.10.1-0.10.00.40.30.00.00.10.6-0.0-0.20.00.70.2
Cu content in liver9.010.919.8-3.5-3.6-3.7-3.5-3.83.4-3.8-3.04.5-3.4-3.3-3.2-2.3-3.32.7-2.83.3-1.3
Fe content in liver1.82.22.8-1.7-1.6-1.5-1.6-1.61.3-1.7-1.21.4-1.6-1.6-1.6-1.3-1.61.3-1.31.4-1.1
K content in liver0.60.61.5-1.1-0.8-1.0-0.8-1.10.8-1.2-0.41.1-0.7-0.6-0.6-0.5-0.40.2-0.0-0.30.7
Mg content in liver2.22.34.5-2.0-1.6-2.0-1.6-1.91.5-2.1-1.31.4-1.6-1.5-1.6-1.3-1.41.1-1.00.6-0.6
Mn content in liver3.64.15.1-2.2-2.0-2.0-2.0-2.12.2-1.9-2.31.7-2.1-2.1-2.1-2.2-2.02.1-2.11.4-1.7
Na content in liver0.50.51.7-0.9-0.7-0.9-0.7-0.90.8-1.0-0.61.3-0.6-0.4-0.4-0.2-0.30.00.0-0.01.1
Rb content in liver0.30.42.7-0.3-1.0-0.5-1.0-0.50.3-0.4-0.31.6-0.4-0.4-0.30.2-0.40.1-0.41.10.0
Se content in liver0.20.20.50.30.60.30.60.3-0.60.30.6-0.50.30.40.40.70.4-0.60.50.10.7
Sr content in liver0.90.92.8-1.0-0.4-0.7-0.4-0.70.8-0.8-0.9-0.6-0.8-0.9-1.0-1.7-0.81.2-0.8-0.5-1.5
Zn content in liver0.10.20.6-0.4-0.2-0.5-0.1-0.50.0-0.70.00.4-0.4-0.4-0.30.4-0.4-0.1-0.10.80.2
Bone: minimum diameter0.00.10.5-0.10.0-0.00.00.0-0.10.00.5-0.20.20.20.1-0.10.2-0.40.4-0.70.4
Time in familiar zone, hab. session 10.20.21.2-0.2-0.1-0.2-0.1-0.20.1-0.4-0.3-0.1-0.5-0.5-0.5-0.1-0.60.4-0.51.1-0.7
Time in novel zone, hab. session 12.42.34.01.51.31.41.31.4-1.31.51.3-0.81.71.71.71.21.8-1.51.7-2.01.8
Total zone transitions, hab. session 16.69.310.3-3.0-3.1-3.2-3.1-3.23.0-3.1-2.92.6-3.1-3.1-3.1-2.8-3.23.1-3.22.7-3.1
Total locomotion distance, hab. session 13.95.56.9-2.4-2.3-2.6-2.3-2.62.3-2.6-2.32.4-2.5-2.4-2.4-1.9-2.42.2-2.42.3-1.9
Locomotion velocity, hab. session 14.96.98.4-2.7-2.6-2.9-2.6-2.82.6-2.8-2.42.5-2.8-2.8-2.7-2.2-2.82.5-2.62.5-2.2
Time in familiar zone, hab. session 21.21.21.81.41.11.31.11.2-1.11.31.1-0.91.21.11.21.21.1-1.00.9-0.40.7
Time in novel zone, hab. session 20.20.20.3-0.5-0.3-0.5-0.3-0.50.3-0.5-0.30.2-0.5-0.4-0.5-0.4-0.40.3-0.30.2-0.3
Total zone transitions, hab. session 24.45.77.8-2.4-2.5-2.5-2.5-2.52.5-2.3-2.12.8-2.5-2.4-2.4-1.9-2.42.1-2.32.7-1.6
Total locomotion distance, hab. session 21.01.33.5-1.2-1.2-1.3-1.2-1.31.2-1.2-0.91.9-1.2-1.1-1.0-0.6-1.10.7-0.91.4-0.1
Locomotion velocity, hab. session 21.21.63.8-1.4-1.3-1.4-1.3-1.41.3-1.4-1.12.0-1.3-1.2-1.2-0.8-1.20.9-1.01.3-0.2
Novel to familiar place preference ratio0.30.31.0-0.4-0.3-0.6-0.3-0.50.4-0.7-0.40.1-0.6-0.6-0.6-0.4-0.70.6-0.70.6-1.0
Novelty place preference0.30.31.3-0.3-0.2-0.5-0.2-0.40.3-0.6-0.4-0.1-0.5-0.6-0.6-0.4-0.70.6-0.70.5-1.1
Time in novel zone, NPP test0.20.21.0-0.1-0.1-0.4-0.1-0.30.1-0.5-0.2-0.1-0.4-0.4-0.4-0.2-0.50.4-0.60.5-1.0
Total zone transitions, NPP test5.88.29.9-3.0-2.9-2.8-2.9-2.92.9-2.7-3.12.9-3.0-3.0-2.9-2.5-3.02.8-3.03.1-2.2
Total locomotion distance, NPP test1.92.64.0-1.7-1.5-1.7-1.5-1.71.5-1.7-1.71.7-1.8-1.7-1.7-1.2-1.71.4-1.62.0-1.0
Locomotion velocity, NPP test2.43.44.3-2.1-1.7-2.0-1.7-1.91.8-1.9-1.91.8-2.0-2.0-1.9-1.6-1.91.7-1.81.8-1.2
Intraocular pressure1.31.92.4-1.4-1.5-1.4-1.3-1.41.0-1.2-1.41.0-1.4-1.5-1.5-1.5-1.51.3-1.51.2-1.4
Delta distance traveled before/after self-admin2.73.03.71.91.71.91.71.9-1.71.81.5-1.81.81.81.81.51.7-1.61.5-1.91.3
Delta ambulatory time before/after self-admin2.93.24.02.01.71.91.71.9-1.71.81.8-1.61.91.91.91.81.8-1.71.7-2.01.5
Parametrial fat weight0.20.31.1-0.5-0.5-0.6-0.4-0.50.4-0.8-0.21.1-0.6-0.6-0.5-0.1-0.60.2-0.51.00.1
Pavlov. Cond. lever latency1.62.04.91.11.31.31.31.4-1.41.31.3-1.31.41.51.40.81.6-1.31.6-2.21.3
Pavlov. Cond. magazine entry latency0.30.31.6-0.2-0.5-0.5-0.5-0.50.6-0.5-0.41.0-0.5-0.5-0.40.0-0.60.3-0.71.3-0.2
Pavlov. Cond. change in total contacts3.84.16.9-1.8-2.0-2.0-2.0-2.12.0-2.0-1.92.3-2.1-2.1-2.0-1.4-2.21.9-2.12.6-1.6
Pavlov. Cond. index score1.11.44.4-0.8-1.1-1.1-1.1-1.11.2-1.1-1.01.5-1.2-1.2-1.1-0.4-1.30.9-1.42.1-0.9
Pavlov. Cond. latency score1.11.44.1-0.9-1.1-1.1-1.1-1.11.2-1.1-1.01.5-1.2-1.2-1.1-0.5-1.31.0-1.42.0-0.9
Pavlov. Cond. lever contacts2.63.16.4-1.6-1.7-1.6-1.7-1.61.7-1.6-1.81.7-1.8-1.9-1.8-1.1-1.91.7-2.02.5-1.6
Pavlov. Cond. magazine entry number0.70.82.60.70.81.00.81.0-0.80.90.7-1.30.90.90.80.31.0-0.61.1-1.60.5
Pavlov. Cond. intertrial magazine entries0.81.01.7-1.3-1.2-1.1-1.2-1.21.0-1.3-0.70.9-1.1-1.0-1.1-0.9-1.00.9-0.70.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.01.24.0-0.7-1.0-1.0-1.0-1.01.1-1.0-0.91.4-1.1-1.1-1.0-0.4-1.20.9-1.32.0-0.9
Pavlov. Cond. response bias0.91.13.8-0.7-0.9-1.0-0.9-1.00.9-0.9-1.01.2-1.1-1.1-1.0-0.4-1.20.9-1.32.0-0.9
Pavlov. Cond. lever latency1.62.23.8-1.4-1.5-1.8-1.5-1.71.5-1.7-1.01.7-1.5-1.5-1.4-0.8-1.61.2-1.41.9-0.9
Pavlov. Cond. magazine entry latency0.50.62.0-0.9-0.8-0.5-0.9-0.60.9-0.5-0.90.0-0.6-0.6-0.7-1.4-0.41.0-0.4-1.0-0.9
Pavlov. Cond. change in total contacts0.40.61.90.60.81.00.81.0-0.70.90.1-1.00.70.70.7-0.00.8-0.50.7-1.40.5
Pavlov. Cond. index score0.40.62.40.50.60.90.60.8-0.60.90.3-0.90.70.70.7-0.00.8-0.40.8-1.60.5
Pavlov. Cond. latency score0.20.32.20.20.30.60.30.6-0.30.60.0-0.70.50.50.4-0.30.6-0.10.5-1.50.3
Pavlov. Cond. lever contacts1.11.52.41.21.31.51.31.5-1.21.40.8-1.41.21.21.20.71.3-1.01.2-1.50.8
Pavlov. Cond. magazine entry number0.20.33.00.1-0.0-0.30.0-0.20.1-0.30.20.7-0.3-0.3-0.10.8-0.4-0.2-0.41.70.1
Pavlov. Cond. intertrial magazine entries1.72.23.9-1.3-1.3-1.7-1.3-1.61.2-1.7-1.21.4-1.5-1.6-1.5-0.9-1.61.2-1.62.0-1.4
Pavlov. Cond. lever-magazine prob. diff.0.60.72.70.60.71.00.71.0-0.71.00.4-1.10.80.80.80.00.9-0.50.9-1.60.5
Pavlov. Cond. response bias0.81.12.30.91.01.31.01.2-1.01.20.6-1.11.11.11.00.51.1-0.81.1-1.50.8
Time in closed arm before self-admin2.93.24.21.81.81.61.81.6-1.91.72.1-1.91.91.91.81.71.8-2.01.8-1.71.5
Time in closed arm after self-admin3.33.47.61.71.81.61.81.5-1.81.42.1-2.61.91.91.71.41.8-1.82.0-2.80.9
Time in open arm before self-admin0.50.61.0-0.6-0.7-0.8-0.7-0.80.6-0.7-0.70.5-0.7-0.8-0.8-0.6-0.80.8-0.90.8-1.0
Time in open arm after self-admin0.50.51.3-0.6-0.5-0.6-0.5-0.50.5-0.5-0.70.3-0.7-0.8-0.7-0.6-0.80.9-0.91.2-1.0
Bone: periosteal estimation0.30.61.30.60.80.60.80.6-0.90.71.1-0.40.70.70.70.80.7-1.10.9-0.31.1
Bone: periosteal perimeter0.91.52.01.21.41.11.21.1-1.31.21.4-1.41.21.21.21.11.2-1.31.2-1.01.0
Bone: post-yield work0.70.91.40.90.91.00.91.0-1.01.11.0-1.11.01.00.90.61.0-0.91.0-1.20.5
Progressive ratio test 1 active lever presses1.01.01.2-1.0-1.1-1.0-1.1-1.01.0-1.1-0.91.1-1.0-1.0-1.0-0.7-1.01.0-0.91.0-1.0
Progressive ratio test 1 breakpoint1.11.11.4-1.1-1.1-1.1-1.1-1.11.1-1.2-0.91.0-1.1-1.1-1.1-0.9-1.11.1-1.00.9-1.2
Progressive ratio test 1 inactive lever presses0.20.30.60.80.50.60.50.6-0.40.60.7-0.40.50.50.50.70.4-0.40.20.20.0
Progressive ratio test 2 active lever presses1.01.11.9-1.1-1.0-1.3-1.0-1.30.8-1.4-0.61.3-1.1-1.1-1.1-0.5-1.20.5-0.91.3-0.5
Progressive ratio test 2 breakpoint0.50.61.2-0.8-0.7-1.0-0.7-1.00.5-1.1-0.31.0-0.8-0.8-0.8-0.2-0.90.3-0.71.1-0.5
Progressive ratio test 2 inactive lever presses0.00.00.3-0.10.1-0.10.1-0.1-0.1-0.30.50.0-0.1-0.1-0.10.3-0.2-0.30.00.4-0.1
Incentive Sensitization - Responses0.20.20.7-0.3-0.0-0.6-0.0-0.6-0.3-0.70.40.6-0.4-0.3-0.30.4-0.4-0.5-0.10.90.3
Incentive Sensitization - Breakpoint0.20.20.7-0.10.2-0.40.2-0.4-0.5-0.50.50.4-0.2-0.1-0.10.7-0.2-0.70.00.80.5
Sum of active levers in priming session hrs 5-65.55.36.3-2.4-2.4-2.4-2.4-2.52.4-2.3-2.52.3-2.3-2.3-2.3-2.4-2.32.3-2.31.4-1.9
Progressive ratio0.20.30.90.40.50.90.50.9-0.50.40.4-0.50.30.30.30.80.2-0.40.30.90.1
Food seeking constrained by brief footshock0.20.21.30.3-0.10.5-0.10.30.00.40.10.90.10.20.30.60.2-0.40.10.31.1
Seeking ratio, punishment vs. effort0.60.71.7-0.8-1.0-1.1-1.0-1.21.0-0.8-0.81.3-0.7-0.7-0.7-0.9-0.60.7-0.7-0.2-0.1
Retroperitoneal fat weight0.20.71.90.71.00.70.90.7-1.00.60.7-0.30.80.80.81.00.8-1.10.9-0.11.4
Reaction time number correct1.21.75.01.31.41.41.31.4-1.41.61.3-2.21.31.21.10.51.2-1.01.1-1.6-0.1
Reaction time mean minus median2.02.63.5-1.9-1.8-1.6-1.8-1.61.8-1.9-1.71.3-1.7-1.7-1.7-1.9-1.61.7-1.50.7-1.1
Reaction time mean minus median AUC2.83.74.8-2.2-2.1-2.0-2.1-2.12.1-2.2-1.81.8-2.0-2.0-2.0-2.0-1.91.9-1.71.0-1.3
Reaction time num false alarms0.91.22.5-0.9-1.3-1.1-1.3-1.11.2-1.1-1.01.6-1.0-1.0-1.0-0.8-1.01.0-1.11.1-0.7
Reaction time num false alarms AUC0.91.32.3-1.0-1.3-1.1-1.3-1.11.3-1.1-1.21.5-1.1-1.1-1.0-0.9-1.11.1-1.21.1-0.7
Reaction time trials correct on left1.21.75.01.31.41.41.31.4-1.41.61.3-2.21.31.21.10.51.2-1.01.1-1.6-0.1
Reaction time trials on left1.11.64.71.21.31.41.31.3-1.31.51.3-2.21.31.21.00.41.1-0.91.0-1.6-0.1
Reaction time mean1.11.52.6-1.4-1.6-1.5-1.5-1.51.5-1.6-0.91.4-1.2-1.2-1.2-1.2-1.11.1-0.90.2-0.4
Reaction time mean AUC1.41.83.1-1.5-1.7-1.6-1.7-1.61.6-1.8-1.01.5-1.4-1.3-1.3-1.3-1.21.2-1.00.3-0.6
Median of all reaction times0.40.61.3-0.9-1.1-1.0-1.0-1.01.0-1.1-0.41.1-0.7-0.7-0.6-0.6-0.60.4-0.40.00.1
Reaction time omissions1.01.42.1-1.3-1.4-1.1-1.3-1.21.4-1.1-1.21.5-1.3-1.2-1.2-1.1-1.21.1-1.10.9-0.5
Reaction time false alarm rate1.62.25.2-1.4-1.7-1.5-1.6-1.51.6-1.6-1.62.3-1.5-1.4-1.3-0.9-1.41.3-1.41.7-0.5
Reaction time premature initiation rate0.30.41.0-0.6-0.6-0.4-0.5-0.40.6-0.2-0.70.0-0.6-0.7-0.7-0.8-0.70.9-0.80.6-1.0
Reaction time premature initiations0.20.21.3-0.00.10.20.10.2-0.00.6-0.2-1.1-0.0-0.1-0.2-0.7-0.10.5-0.3-0.3-1.2
Std. dev. reaction times1.92.73.7-1.9-1.9-1.8-1.9-1.81.8-1.9-1.51.5-1.7-1.6-1.6-1.8-1.51.6-1.40.4-0.9
Reaction time trials completed1.11.64.71.21.31.41.31.3-1.31.51.3-2.21.31.21.00.41.1-0.91.0-1.6-0.1
Reaction time trials AUC1.11.64.91.21.41.41.31.3-1.31.61.3-2.21.31.21.10.51.1-0.91.0-1.5-0.1
Run reversals in cocaine runway, females0.30.20.7-0.4-0.5-0.6-0.5-0.50.5-0.3-0.60.1-0.3-0.3-0.4-0.9-0.30.5-0.4-0.6-0.7
Run reversals in cocaine runway, males1.41.42.31.21.41.41.41.4-1.41.11.3-1.31.01.01.01.50.9-1.21.10.30.7
Latency to leave start box in cocaine runway5.66.07.72.32.62.42.62.4-2.52.12.4-2.82.42.52.42.12.5-2.42.7-2.82.1
Latency to leave start box in cocaine runway, F8.89.613.92.93.23.13.23.2-3.13.12.9-3.63.13.13.02.53.2-2.93.3-3.72.4
Latency to leave start box in cocaine runway, M0.20.21.20.10.40.00.40.0-0.4-0.30.30.50.10.20.30.70.2-0.60.50.41.1
Std. dev. time between licks in bursts0.70.91.50.90.91.10.90.9-0.91.20.7-0.60.91.01.00.91.0-1.00.9-0.61.2
Total sessions with >9 infusions0.80.82.2-1.1-1.1-0.8-1.1-0.81.1-0.8-1.41.5-0.8-0.7-0.7-0.9-0.60.7-0.50.50.3
Short access day 1 total inactive lever presses0.40.52.4-0.5-0.4-0.3-0.4-0.30.3-0.3-0.7-0.3-0.6-0.7-0.8-1.2-0.70.7-0.90.5-1.6
Short access day 10 total inactive lever presses0.40.41.50.70.80.60.80.6-0.70.61.0-1.20.50.40.40.50.3-0.50.3-0.3-0.5
Short access day 1 total infusions0.10.10.5-0.3-0.30.1-0.30.10.20.0-0.70.1-0.2-0.2-0.2-0.7-0.10.4-0.2-0.1-0.2
Short access day 10 total infusions0.10.10.7-0.4-0.4-0.3-0.4-0.30.3-0.40.00.4-0.1-0.1-0.1-0.1-0.0-0.10.3-0.80.4
Short access total infusions0.00.00.4-0.1-0.20.1-0.20.10.10.0-0.3-0.20.10.10.0-0.30.10.10.2-0.6-0.1
Short access day 1 locomotion0.10.11.0-0.1-0.20.2-0.20.20.10.1-0.30.60.10.20.20.10.3-0.30.4-0.11.0
Short access day 10 total locomotion0.91.14.3-1.1-1.4-1.1-1.4-1.11.2-1.1-0.92.1-0.9-0.8-0.7-0.4-0.70.3-0.50.30.9
Short access total locomotion0.30.31.3-0.5-0.8-0.3-0.8-0.30.6-0.3-0.51.2-0.2-0.1-0.0-0.10.0-0.10.3-0.41.1
One hour access (0.3 mA shock)0.80.92.1-0.8-0.9-1.0-0.9-1.00.8-1.1-0.61.0-1.0-1.0-1.0-0.5-1.10.8-0.91.5-1.1
Compulsive drug intake7.27.39.6-2.6-2.7-2.7-2.7-2.72.6-2.7-2.52.3-2.6-2.7-2.7-2.7-2.72.9-2.92.6-3.1
One hour access (shock baseline)1.31.53.31.11.31.11.31.1-1.21.01.4-0.51.11.11.21.71.1-1.61.3-0.41.8
Social response proportion2.22.43.1-1.5-1.6-1.7-1.6-1.71.8-1.4-1.71.8-1.5-1.5-1.5-1.4-1.51.5-1.61.3-0.8
Social responses0.10.11.20.2-0.00.0-0.0-0.00.30.2-0.50.3-0.1-0.2-0.10.1-0.30.3-0.51.1-0.2
Social time0.20.33.00.50.20.30.20.2-0.00.50.4-0.10.0-0.00.10.8-0.2-0.1-0.41.7-0.3
Soleus weight1.54.34.92.22.02.12.02.0-2.12.12.2-1.72.22.22.22.02.2-2.22.2-2.11.8
Bone: stiffness0.10.10.40.10.40.00.40.0-0.50.10.6-0.10.20.20.20.20.2-0.50.4-0.00.4
Tibialis anterior weight0.10.41.2-0.2-0.5-0.3-0.7-0.30.5-0.3-0.60.7-0.5-0.5-0.5-0.4-0.60.7-0.91.1-1.1
Time to tail flick, vehicle, before self-admin1.41.42.1-1.0-1.3-1.2-1.3-1.21.3-1.1-1.01.2-1.1-1.1-1.1-1.1-1.21.4-1.21.4-1.4
Time to tail flick, vehicle, after self-admin0.80.82.20.71.10.61.10.7-0.90.90.8-1.50.90.80.80.60.8-0.90.9-1.40.5
Time to tail flick, test, before self-admin0.50.51.50.80.60.80.60.8-0.50.50.7-0.70.90.90.80.40.9-0.50.8-1.20.3
Time to tail flick, test, after self-admin0.50.51.50.70.60.70.60.7-0.60.70.7-0.90.80.70.70.20.7-0.40.6-1.2-0.0
Delta time to tail flick, vehicle, before/after SA3.13.04.91.72.01.62.01.7-1.81.91.5-2.21.71.71.71.51.7-1.81.7-1.91.3
Delta time to tail flick, test, before/after SA0.40.40.6-0.6-0.5-0.5-0.5-0.60.5-0.4-0.70.6-0.7-0.7-0.6-0.6-0.70.7-0.70.7-0.5
Tibia length0.61.72.31.21.21.21.31.2-1.31.41.3-1.41.41.41.31.01.4-1.31.5-1.50.8
Ambulatory time before self-admin1.61.74.9-1.3-0.9-1.6-0.9-1.50.9-1.5-1.21.5-1.5-1.4-1.3-0.6-1.50.8-1.32.2-0.5
Ambulatory time after self-admin0.40.41.10.70.80.30.80.4-0.80.40.5-0.10.50.50.61.00.4-1.00.4-0.21.1
Bone: tissue strength1.00.92.20.81.01.01.11.0-1.11.01.0-1.51.00.90.80.50.9-0.81.0-1.10.1
Total heroin consumption0.70.82.3-0.5-0.8-0.7-0.8-0.90.9-0.4-0.90.7-0.8-0.8-0.8-0.8-0.91.1-1.11.1-1.5
Bone: trabecular number0.20.31.40.30.30.10.30.1-0.50.10.40.60.30.40.40.90.3-0.80.50.31.2
Bone: trabecular spacing0.10.10.80.40.10.30.10.3-0.00.50.3-0.00.10.00.10.4-0.10.0-0.20.9-0.2
Bone: trabecular thickness3.34.08.21.82.11.92.01.9-2.11.91.8-2.52.12.11.91.12.1-1.82.2-2.91.4
Bone: trabecular tissue density0.10.10.4-0.3-0.1-0.0-0.1-0.10.10.1-0.3-0.4-0.0-0.1-0.1-0.60.00.3-0.0-0.5-0.4
Water consumed over 24 hours0.10.10.4-0.2-0.2-0.1-0.2-0.10.2-0.1-0.4-0.3-0.2-0.3-0.3-0.4-0.30.5-0.3-0.1-0.7
Number of responses in last shaping day2.02.14.51.51.51.51.51.5-1.71.51.8-2.11.51.41.30.91.4-1.11.3-1.2-0.1