Hub : Genes

Smtn

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Smtn 0.12 0.06 3.6e-06 0.05 0.06 0.05 0.06 3.0e-05 1.3e-06 1.9e-05 2.1e-06
2 Adipose gene expression Smtn 0.05 0.03 2.0e-03 0.02 0.02 0.02 0.02 1.2e-03 4.4e-03 1.6e-03 1.9e-03
3 Adipose intron excision ratio chr14_82634918_82635013 0.07 0.04 8.2e-06 0.04 0.04 0.04 0.04 9.7e-06 2.9e-05 5.7e-05 4.3e-05
4 Eye intron excision ratio chr14_82635084_82635686 0.58 0.15 3.5e-04 0.08 0.2 0.14 0.19 2.2e-02 5.2e-04 3.7e-03 7.4e-04
5 Brain gene expression Smtn 0.67 0.06 0.0e+00 0.47 0.45 0.47 0.48 1.0e-48 1.4e-46 2.2e-49 2.7e-50
6 Brain intron excision ratio chr14_82634918_82635013 0.04 0.03 4.2e-03 0.02 0.01 0.01 0.01 4.7e-03 4.2e-02 3.3e-02 3.8e-02
7 Liver intron excision ratio chr14_82634918_82635013 0.06 0.03 4.9e-04 0.04 0.02 0.03 0.03 2.7e-05 9.0e-04 1.2e-04 1.1e-04
8 Liver intron excision ratio chr14_82627382_82627585 0.04 0.02 2.4e-04 0.03 0.02 0.03 0.03 1.2e-04 1.1e-03 7.4e-04 7.6e-04
9 Liver intron excision ratio chr14_82627385_82627585 0.04 0.02 2.7e-04 0.03 0.02 0.02 0.03 1.2e-04 1.2e-03 5.9e-03 7.2e-04
10 Liver gene expression Smtn 0.13 0.06 1.7e-10 0.05 0.09 0.09 0.05 2.1e-06 5.6e-10 1.0e-09 2.3e-06
11 OFC alternative polyA XM_063272944.1 0.13 0.08 8.3e-03 0.05 0.06 0.06 0.07 2.5e-02 1.6e-02 1.4e-02 8.0e-03
12 BLA intron excision ratio chr14_82634918_82635013 0.14 0.09 7.8e-03 0 0.02 -0 0.01 2.0e-01 4.4e-02 3.8e-01 9.2e-02
13 OFC alternative polyA XM_017599120.3 0.15 0.09 3.8e-03 0.06 0.08 0.07 0.1 1.4e-02 5.7e-03 7.8e-03 2.7e-03
14 NAcc gene expression Smtn 0.06 0.03 6.5e-05 0.03 0.02 0.02 0.03 4.5e-05 2.1e-04 1.2e-04 4.4e-05
15 Brain alternative TSS XM_008770259.4 0.03 0.02 9.5e-03 0 0.02 0 0.01 1.1e-01 7.4e-03 2.4e-01 5.9e-02
16 OFC alternative polyA XM_063272944.1 0.14 0.08 5.7e-03 0.05 0.07 0.05 0.09 2.1e-02 9.6e-03 2.2e-02 4.7e-03
17 NAcc intron excision ratio chr14_82634918_82635013 0.04 0.03 7.7e-04 0.02 0.02 0.02 0.02 9.6e-04 3.5e-04 8.6e-04 3.5e-04
18 LHb gene expression Smtn 0.54 0.14 5.9e-11 0.24 0.35 0.44 0.41 2.5e-06 4.3e-09 8.1e-12 6.0e-11
19 BLA gene expression Smtn 0.14 0.08 5.8e-03 0.04 0.01 0.05 0.01 3.0e-03 1.4e-01 1.9e-03 7.5e-02
20 LHb alternative TSS XM_017599120.3 0.12 0.08 1.0e-02 0.04 0.05 0.02 0.04 4.0e-02 2.8e-02 9.0e-02 4.2e-02
21 OFC alternative polyA XM_017599120.3 0.14 0.08 4.8e-03 0.09 0.07 0.06 0.09 4.4e-03 7.7e-03 1.4e-02 3.6e-03
22 Liver isoform ratio XM_006251196.5 0.03 0.02 3.3e-04 0.03 0.02 0.02 0.02 1.3e-04 1.1e-03 5.9e-03 1.1e-03
23 pVTA gene expression Smtn 0.07 0.05 5.9e-03 0.04 0.04 0.02 0.03 4.9e-04 6.0e-04 8.5e-03 1.9e-03
24 pVTA intron excision ratio chr14_82634918_82635013 0.22 0.1 5.8e-06 0.08 0.07 0.07 0.07 3.9e-07 2.0e-06 2.8e-06 3.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.40.72.2-1.51.21.1-0.01.01.01.0-0.80.8-1.1-0.80.60.60.4-1.0-0.50.7-1.30.2-0.60.30.3-0.4-0.2
Area under the delay curve3.94.513.13.1-3.6-3.6-0.7-2.9-3.5-3.50.0-0.0-0.2-0.9-1.11.1-1.6-0.7-1.0-3.3-0.8-2.1-1.21.2-2.02.1-2.3
BMI with tail0.51.95.42.3-2.0-2.00.5-1.5-2.1-2.10.8-0.81.6-0.30.40.6-0.01.0-0.5-1.71.1-0.2-0.11.0-2.32.2-0.2
BMI without tail0.41.36.21.5-0.7-0.7-0.3-0.3-0.6-0.61.5-1.52.50.60.4-0.40.72.10.4-0.12.1-0.31.1-0.0-1.31.21.3
Body weight1.56.421.84.7-3.4-3.5-2.2-3.2-3.8-3.82.8-2.83.11.2-1.3-0.8-1.42.30.9-2.72.1-2.41.2-0.2-2.01.8-0.6
Weight adjusted by age1.01.54.72.2-1.7-1.7-1.1-1.1-1.2-1.21.8-1.81.51.1-0.7-0.9-0.71.20.9-0.51.1-1.40.8-0.6-0.50.60.0
Bone surface0.10.10.70.1-0.1-0.2-0.1-0.0-0.2-0.2-0.10.1-0.3-0.50.10.50.0-0.4-0.3-0.1-0.7-0.8-0.40.3-0.30.4-0.4
Bone volume0.10.10.7-0.40.40.3-0.30.30.20.2-0.20.2-0.4-0.50.20.40.1-0.5-0.20.2-0.8-0.5-0.30.10.00.0-0.3
Breakpoint value in progressive ratio session0.30.31.10.4-0.5-0.6-0.2-0.7-0.9-0.90.1-0.1-0.4-0.5-0.10.6-0.5-0.5-0.4-0.8-0.8-0.8-0.40.5-0.80.0-1.0
Number of licking bursts0.61.14.90.8-0.3-0.2-2.2-0.2-0.2-0.21.5-1.51.31.3-0.9-1.2-0.41.31.30.21.1-1.01.3-1.10.6-0.60.4
Context. condit. distance diff. score0.91.12.8-1.61.51.21.41.71.41.4-0.40.4-0.1-0.51.50.51.5-0.1-0.41.30.01.4-0.30.4-0.30.40.9
Locomotion velocity, session 10.30.31.8-0.3-0.1-0.11.30.00.30.3-0.50.5-1.3-0.1-0.30.0-0.5-0.9-0.00.2-0.9-0.4-0.5-0.10.6-0.5-0.4
Locomotion distance, session 10.50.61.4-1.20.70.61.11.21.11.1-0.80.8-0.6-0.70.90.71.0-0.5-0.61.0-0.60.6-0.60.5-0.10.20.4
Locomotion velocity, session 21.41.68.8-1.40.90.60.9-0.10.70.7-1.21.2-3.0-0.2-1.1-0.1-1.3-2.20.10.2-2.1-0.2-0.8-0.61.9-1.8-1.3
Locomotion distance, session 21.92.68.5-2.21.61.42.91.51.41.4-2.02.0-1.9-1.71.71.51.4-1.7-1.50.9-1.61.9-1.61.3-0.40.4-0.1
Locomotion velocity, session 30.50.51.5-0.80.50.41.20.90.50.5-0.80.8-0.5-0.91.10.90.9-0.5-0.80.5-0.50.9-0.80.8-0.60.70.1
Locomotion distance, session 30.30.30.90.8-0.9-0.80.8-0.6-0.7-0.7-0.20.2-0.5-0.3-0.30.4-0.5-0.5-0.4-0.7-0.4-0.4-0.50.4-0.50.6-0.7
Stereotopy head waving bouts, day 30.60.71.9-1.31.21.40.41.21.31.30.1-0.1-0.10.40.5-0.40.60.10.41.30.30.80.3-0.50.7-0.90.8
Stereotopy head waving duration, day 31.21.43.8-1.71.71.91.21.91.91.9-0.20.20.20.11.3-0.11.50.30.01.90.61.10.2-0.00.2-0.41.5
Locomotion velocity, session 70.40.41.60.8-0.4-0.50.2-1.2-0.9-0.90.8-0.8-0.40.6-0.7-0.6-1.0-0.20.7-0.8-0.30.10.2-0.70.5-0.4-0.9
Locomotion distance, session 70.50.72.6-0.70.30.41.60.30.20.2-0.80.8-1.1-0.91.00.90.5-1.1-0.80.0-1.11.1-1.10.8-0.60.7-0.6
Stereotopy head waving bouts, day 70.20.31.20.8-0.5-0.40.2-0.2-0.6-0.60.7-0.70.7-0.00.60.20.40.4-0.1-0.30.4-0.1-0.10.3-1.01.10.0
Stereotopy head waving duration, day 70.30.41.30.8-0.3-0.2-0.00.1-0.4-0.40.9-0.91.10.10.70.00.70.80.1-0.00.8-0.10.20.2-1.01.10.4
Locomotion velocity, session 81.11.34.1-2.02.01.51.41.41.81.8-0.50.5-1.3-0.10.5-0.10.3-0.80.21.5-0.80.6-0.2-0.51.3-1.30.4
Locomotion distance, session 83.14.612.4-3.53.33.02.73.33.23.2-1.21.2-0.7-0.92.60.72.8-0.4-0.72.8-0.32.6-0.50.50.2-0.11.8
Degree of sensitization distance1.71.75.7-2.42.42.30.81.82.02.0-0.40.4-0.40.01.2-0.21.2-0.10.21.8-0.12.00.1-0.30.8-0.81.1
Degree of sensitization stereotypy0.30.41.31.0-0.5-0.5-0.3-0.3-0.7-0.70.8-0.81.00.10.40.00.40.70.0-0.30.6-0.20.10.2-1.01.10.1
Conditioned locomotion1.31.54.0-0.70.30.21.11.00.20.2-1.21.2-0.0-1.82.01.81.7-0.6-1.70.3-0.71.3-1.31.7-1.81.80.0
Cocaine response after cond. corrected0.60.71.30.5-1.1-1.0-0.7-0.7-0.7-0.7-1.11.1-1.0-0.7-0.70.7-0.7-1.1-0.8-0.9-0.9-1.0-0.90.7-0.30.4-1.0
Cocaine response after cond. not corrected0.91.13.21.2-1.8-1.7-1.7-1.3-1.2-1.2-0.60.6-0.5-0.3-1.40.3-1.2-0.7-0.4-1.3-0.6-1.6-0.40.4-0.20.3-1.1
Cocaine response before conditioning0.60.71.50.9-0.8-0.8-1.2-0.8-0.5-0.51.0-1.00.71.0-1.1-1.0-0.70.81.0-0.40.6-0.71.0-0.90.6-0.50.1
Saline control response0.10.12.2-0.30.30.21.50.00.20.2-0.20.2-0.7-0.10.10.10.0-0.4-0.00.1-0.40.3-0.2-0.10.3-0.1-0.1
Bone: connectivity density0.30.51.0-1.00.60.50.30.80.70.7-0.90.9-0.8-0.90.60.80.6-0.9-0.80.5-0.90.2-0.80.6-0.20.2-0.1
Bone: cortical apparent density0.20.31.10.1-0.3-0.30.20.3-0.3-0.30.1-0.10.7-0.60.90.70.80.4-0.5-0.1-0.00.3-0.20.6-1.11.00.2
Bone: cortical area2.53.89.83.1-2.1-2.1-2.4-2.1-2.2-2.22.5-2.52.71.8-1.6-1.5-1.32.41.5-1.42.2-1.71.9-1.1-0.30.30.2
Bone: cortical porosity0.30.30.90.4-0.6-0.6-0.5-0.7-0.6-0.6-0.60.6-0.8-0.2-0.80.2-0.8-0.8-0.2-0.7-0.6-0.7-0.50.20.1-0.2-0.9
Bone: cortical porosity0.00.00.10.2-0.3-0.2-0.3-0.2-0.2-0.2-0.30.3-0.2-0.1-0.20.1-0.2-0.2-0.2-0.20.0-0.3-0.20.2-0.1-0.0-0.3
Bone: cortical thickness1.72.77.72.7-1.9-1.9-2.1-1.6-2.0-2.02.0-2.02.81.2-0.9-0.9-0.62.30.9-1.32.1-0.91.4-0.5-0.90.90.3
Bone: cortical thickness1.11.34.6-0.5-0.1-0.10.61.50.60.6-0.70.71.1-1.21.91.32.20.5-1.30.80.41.0-0.61.4-1.81.81.2
Bone: cortical tissue density0.20.31.20.2-0.3-0.40.20.2-0.3-0.30.0-0.00.7-0.70.90.70.80.3-0.6-0.1-0.10.2-0.30.7-1.11.00.2
Condit. Reinf. active minus inactive responses0.60.62.00.3-0.4-0.41.4-0.6-0.6-0.6-1.11.1-1.2-0.8-0.20.8-0.2-1.1-0.9-0.8-1.0-0.5-1.00.8-0.40.4-0.9
Condit. Reinf. active-inactive response ratio0.91.05.8-0.60.30.42.40.10.20.2-1.51.5-1.7-1.00.11.00.3-1.5-1.0-0.2-1.2-0.1-1.20.9-0.20.0-0.5
Condit. Reinf. active responses0.10.10.90.1-0.00.11.0-0.1-0.2-0.2-0.60.6-0.4-0.4-0.10.40.2-0.4-0.4-0.2-0.3-0.4-0.40.4-0.20.3-0.2
Condit. Reinf. inactive responses0.60.82.50.6-0.20.1-1.6-0.1-0.1-0.11.3-1.31.51.0-0.4-1.0-0.21.41.00.21.1-0.41.2-0.90.4-0.10.6
Incentive salience index mean0.50.61.51.1-1.0-0.90.6-1.2-1.2-1.2-0.30.3-0.6-0.4-0.70.4-0.7-0.5-0.4-1.2-0.6-1.2-0.50.4-0.40.5-1.0
Condit. Reinf. lever presses0.50.62.41.5-1.3-1.0-0.3-1.1-1.2-1.20.7-0.70.70.1-0.60.0-0.40.50.1-0.80.3-1.20.20.1-0.60.8-0.4
Condit. Reinf. active minus inactive responses0.60.81.5-0.20.70.7-0.00.30.70.71.1-1.10.81.2-0.3-1.2-0.01.11.20.91.10.31.2-1.21.0-0.91.1
Condit. Reinf. active-inactive response ratio0.20.20.60.2-0.5-0.20.8-0.3-0.3-0.3-0.50.5-0.4-0.60.20.60.1-0.5-0.6-0.4-0.6-0.1-0.60.6-0.60.6-0.3
Condit. Reinf. active responses0.40.51.3-0.81.20.91.10.40.90.90.3-0.3-0.10.60.1-0.70.00.30.70.80.30.90.6-0.70.9-0.90.7
Condit. Reinf. inactive responses0.60.82.8-1.21.71.31.00.81.21.20.2-0.2-0.00.60.3-0.70.30.30.71.10.41.00.6-0.71.0-1.10.9
Condit. Reinf. lever presses0.10.10.60.10.30.20.8-0.1-0.1-0.10.5-0.50.60.40.3-0.3-0.10.60.30.00.80.40.4-0.2-0.10.10.4
Condit. Reinf. lever reinforcers received0.20.21.6-0.50.80.51.30.20.50.50.1-0.1-0.10.30.3-0.30.10.10.30.40.20.80.2-0.30.4-0.40.5
Conditioned reinforcement - actives0.61.03.11.6-1.6-1.6-0.6-1.5-1.8-1.80.3-0.3-0.0-0.1-0.50.2-1.0-0.3-0.2-1.6-0.4-0.5-0.40.3-0.70.7-1.2
Conditioned reinforcement - inactives1.52.26.22.5-2.4-2.4-0.7-2.4-2.3-2.30.7-0.7-0.00.5-1.6-0.3-2.0-0.10.3-2.0-0.1-1.7-0.1-0.1-0.40.4-1.5
Conditioned locomotion0.91.13.11.6-1.2-1.2-1.7-1.3-1.2-1.21.6-1.60.70.9-0.9-0.9-1.20.71.0-0.90.2-0.90.7-0.90.2-0.2-0.6
Patch foraging indifference point 0 sec0.10.20.60.3-0.0-0.3-0.6-0.0-0.1-0.10.7-0.70.80.5-0.1-0.5-0.10.70.50.10.6-0.20.6-0.40.0-0.20.6
Patch foraging indifference point AUC0.20.31.4-0.20.30.31.1-0.30.20.2-0.20.2-1.20.1-0.5-0.1-0.8-0.80.10.0-0.8-0.4-0.2-0.20.6-0.8-0.5
Delay disc. indifference point, 0s delay5.15.514.52.1-3.2-3.10.4-1.7-3.2-3.2-1.31.3-0.3-2.61.02.80.2-1.4-2.7-2.9-1.4-0.5-2.53.0-3.83.6-2.1
Delay disc. indifference point, 16s delay2.93.28.21.9-2.6-2.6-0.5-2.6-2.7-2.7-0.90.9-1.3-1.0-1.41.0-1.9-1.5-1.0-2.9-1.5-1.2-1.31.0-0.80.9-2.8
Delay disc. indifference point, 2s delay2.83.110.02.4-3.2-3.1-0.7-1.8-2.6-2.6-0.70.70.1-1.2-0.51.4-0.6-0.6-1.5-2.3-0.5-1.2-1.31.7-2.32.5-1.3
Delay disc. indifference point, 24s delay3.23.67.71.8-2.7-2.80.2-1.8-2.5-2.5-1.01.0-1.2-1.9-0.01.9-0.6-1.7-1.8-2.6-1.9-1.0-2.01.8-2.12.5-2.6
Delay disc. indifference point, 4s delay2.32.47.72.5-2.8-2.8-0.9-2.3-2.5-2.50.2-0.2-0.0-0.4-1.20.5-1.5-0.4-0.4-2.3-0.5-1.8-0.60.6-1.21.1-1.5
Delay disc. indifference point, 8s delay1.21.44.02.0-1.7-1.7-0.3-1.8-1.8-1.81.3-1.30.50.5-0.9-0.4-1.20.50.6-1.50.3-2.00.3-0.4-0.40.5-0.6
Indifference point function ln k0.10.21.7-0.10.1-0.0-1.3-0.2-0.1-0.10.1-0.10.00.3-0.5-0.4-0.30.00.4-0.1-0.1-0.30.3-0.50.7-0.6-0.2
Indifference point function log k0.10.21.7-0.10.1-0.0-1.3-0.2-0.1-0.10.1-0.10.00.3-0.5-0.4-0.30.00.4-0.1-0.1-0.30.3-0.50.7-0.6-0.2
Patch foraging total patch changes 0 sec0.20.40.80.5-0.1-0.4-0.6-0.2-0.2-0.20.9-0.90.80.8-0.4-0.7-0.30.90.70.10.8-0.40.8-0.60.2-0.40.6
Patch foraging total patch changes 12 sec0.20.20.90.5-0.2-0.1-0.5-0.1-0.3-0.30.7-0.71.00.40.1-0.30.00.80.3-0.00.80.60.5-0.1-0.40.20.4
Patch foraging total patch changes 18 sec0.20.21.40.7-0.3-0.40.3-0.5-0.3-0.30.7-0.70.00.6-0.6-0.5-0.70.20.5-0.10.3-1.20.3-0.50.2-0.30.0
Patch foraging total patch changes 24 sec1.01.75.3-1.31.71.42.32.01.51.5-0.00.00.8-0.42.20.42.00.7-0.41.70.71.7-0.00.5-0.80.61.8
Patch foraging total patch changes 6 sec0.50.82.00.8-0.3-0.5-0.6-0.9-0.5-0.51.4-1.40.31.2-0.9-1.2-1.20.61.3-0.30.5-0.40.9-1.20.8-0.9-0.2
Patch foraging time to switch 0 sec1.02.18.4-0.80.71.10.32.00.80.80.1-0.12.1-0.82.71.02.91.3-0.91.21.51.6-0.11.2-2.12.01.8
Patch foraging water rate 0 sec2.24.611.82.1-0.9-1.4-1.9-2.3-1.0-1.02.2-2.20.52.9-3.4-2.9-3.11.22.8-0.71.2-2.42.2-2.82.6-2.4-0.3
Patch foraging water rate 12 sec0.71.63.81.0-0.2-0.5-0.8-1.0-0.3-0.31.5-1.50.71.9-1.8-1.9-1.41.21.7-0.21.4-1.11.6-1.61.4-1.50.3
Patch foraging water rate 18 sec1.82.85.7-0.21.10.8-2.00.71.11.11.9-1.92.22.2-0.6-2.10.22.42.01.52.40.12.4-1.91.5-1.42.1
Patch foraging water rate 24 sec3.85.413.71.10.30.1-1.8-0.60.40.43.0-3.02.13.7-2.2-3.6-1.52.83.40.82.9-0.93.3-3.32.8-2.31.7
Patch foraging water rate 6 sec3.04.49.81.30.0-0.4-2.0-0.80.10.13.0-3.02.13.1-2.1-3.0-1.42.63.00.52.5-1.43.0-2.82.1-2.01.3
Seeking ratio, delayed vs. immediate footshock0.91.13.8-0.20.10.0-0.3-1.1-0.2-0.20.3-0.3-1.90.4-1.6-0.7-1.8-1.20.8-0.5-1.7-0.50.1-1.21.8-2.0-1.5
Distance traveled before self-admin0.50.72.7-0.80.20.30.70.40.30.3-1.01.0-1.6-1.10.41.0-0.0-1.5-0.90.1-1.60.5-1.10.7-0.30.1-1.1
Distance traveled after self-admin0.70.92.2-0.3-0.5-0.40.70.2-0.2-0.2-1.31.3-1.1-1.20.81.20.2-1.3-1.2-0.3-1.30.5-1.51.1-0.81.1-1.1
Extensor digitorum longus weight1.97.418.74.3-3.3-3.2-3.7-3.3-3.0-3.03.3-3.32.42.5-3.0-2.3-2.92.22.3-2.31.9-3.12.1-1.90.3-0.3-0.7
Bone: elastic displacement0.70.82.1-0.30.91.0-0.90.80.80.80.8-0.81.50.70.3-0.70.71.40.71.01.20.21.1-0.60.4-0.41.4
Bone: elastic work2.12.87.90.60.40.5-2.40.50.50.52.2-2.22.82.0-0.6-1.80.42.71.81.12.6-0.92.4-1.60.8-0.92.0
Bone: endosteal estimation0.40.92.10.30.40.3-0.9-0.10.20.21.4-1.40.81.4-0.7-1.4-0.41.01.40.51.0-0.71.2-1.31.0-1.10.6
Bone: endosteal perimeter0.61.33.01.4-0.8-0.9-1.3-1.4-0.9-0.91.4-1.40.61.4-1.6-1.3-1.40.81.3-0.70.8-1.71.1-1.20.8-0.7-0.3
Epididymis fat weight0.41.54.42.0-1.5-1.3-1.5-1.4-2.1-2.11.3-1.31.60.10.00.1-0.41.00.1-1.60.7-0.40.20.3-1.51.4-0.7
Delta time in closed arm before/after self-admin2.11.97.3-2.01.31.31.41.81.11.1-1.41.4-0.6-1.42.11.31.9-0.9-1.30.8-0.92.7-1.21.2-0.71.00.2
Delta time in open arm before/after self-admin2.12.16.12.5-2.2-2.2-0.7-2.3-2.3-2.31.2-1.20.60.6-1.3-0.5-1.70.50.6-2.00.5-2.00.4-0.4-0.40.3-0.9
Diff in mean of infusions in LGA sessions1.61.94.1-0.7-0.0-0.11.80.5-0.2-0.2-1.81.8-1.3-2.01.32.01.1-1.5-2.0-0.5-1.60.7-1.91.9-1.51.4-1.0
Delay discount exponential model param3.84.212.8-3.13.63.60.72.93.43.4-0.10.10.10.81.1-0.91.60.60.93.10.72.11.0-1.11.9-2.02.1
Extinction: sum of active levers before priming1.61.84.40.8-1.6-1.50.7-1.3-1.6-1.6-0.90.9-1.6-1.4-0.01.3-0.8-1.7-1.1-1.8-2.0-0.4-1.61.0-0.91.3-2.1
Active lever presses in extinction session 61.61.63.30.2-1.0-1.10.1-0.5-1.2-1.2-1.31.3-1.1-1.80.51.8-0.0-1.5-1.7-1.3-1.6-0.4-1.61.7-1.71.1-1.7
Bone: final force1.11.76.31.1-0.2-0.2-1.00.0-0.2-0.22.1-2.12.51.6-0.0-1.40.52.31.40.42.4-0.41.7-1.0-0.10.21.4
Bone: final moment1.21.95.61.1-0.1-0.2-1.5-0.2-0.2-0.22.2-2.22.41.8-0.4-1.60.12.31.60.32.3-0.41.8-1.30.3-0.21.3
Food consumed during 24 hour testing period1.11.54.40.70.0-0.0-0.5-1.1-0.2-0.21.3-1.3-0.11.8-1.9-1.9-1.70.61.8-0.10.7-1.01.4-1.81.9-2.1-0.1
Glucose6.29.728.84.0-3.8-3.7-0.3-4.9-3.5-3.51.0-1.0-2.81.3-4.8-1.4-5.4-1.81.5-3.8-1.9-5.2-0.2-1.61.8-2.1-4.0
Heart weight0.40.61.61.3-1.0-1.0-0.7-1.2-0.9-0.91.1-1.10.30.7-0.8-0.6-0.90.40.7-0.70.2-1.00.5-0.60.2-0.3-0.4
Delay discount hyperbolic model param3.84.313.2-3.13.63.60.82.83.43.4-0.10.10.00.81.1-1.01.50.60.93.10.62.21.0-1.21.9-2.12.0
Intermittent access intake day 1-15 change0.40.82.10.6-1.1-1.10.2-1.1-1.3-1.3-1.11.1-1.0-0.4-0.80.5-1.0-1.0-0.6-1.5-0.7-0.2-0.80.6-0.20.2-1.2
Intermittent access intake escalation0.51.12.80.9-1.4-1.4-0.2-1.4-1.5-1.5-0.90.9-1.1-0.3-1.10.3-1.4-1.1-0.5-1.7-0.8-0.5-0.70.5-0.10.1-1.4
Intermittent access intake escalation 20.20.31.00.4-0.4-0.4-0.8-0.6-0.5-0.5-0.10.10.00.6-1.0-0.5-0.80.10.4-0.60.4-0.40.4-0.40.6-0.6-0.1
Intermitt. access day 1 inactive lever presses0.10.51.31.0-1.1-1.0-0.3-1.1-1.0-1.0-0.20.2-0.4-0.0-0.80.0-1.0-0.4-0.1-1.0-0.4-0.5-0.30.1-0.10.1-0.8
Intermitt. access day 15 inactive lever presses0.91.95.32.2-1.8-1.8-0.1-2.3-1.6-1.60.8-0.80.11.2-2.2-1.1-2.10.41.0-1.40.6-2.30.7-0.90.7-0.7-0.7
Intermitt. access escalation Index0.30.51.9-0.80.70.71.40.80.60.6-1.11.1-0.2-0.60.60.61.0-0.2-0.80.40.30.2-0.40.7-0.40.40.7
Intermittent access day 1 total infusions0.61.02.61.1-1.5-1.5-0.2-1.0-1.4-1.4-0.20.2-0.1-1.00.31.1-0.3-0.5-1.0-1.2-0.8-0.4-1.01.1-1.61.6-1.0
Intermittent access day 15 total infusions1.31.95.11.9-2.3-2.2-0.7-2.0-2.2-2.2-0.20.2-0.6-0.3-1.00.4-1.6-0.8-0.5-2.1-0.8-0.9-0.80.6-0.80.8-1.8
Intermittent access terminal intake (last 3 days)0.81.12.81.5-1.7-1.6-0.9-1.7-1.7-1.70.0-0.0-0.40.1-1.1-0.0-1.5-0.4-0.0-1.6-0.4-0.8-0.30.1-0.20.2-1.3
Intermittent access total infusions1.11.33.31.5-1.8-1.8-1.0-1.8-1.8-1.80.0-0.0-0.6-0.0-1.20.1-1.6-0.7-0.1-1.8-0.8-1.0-0.50.1-0.20.2-1.6
Intermittent access day 1 locomotion0.10.20.9-0.50.30.30.40.20.40.4-0.10.1-0.5-0.40.60.40.2-0.5-0.20.3-0.90.8-0.50.2-0.20.2-0.3
Intermittent access day 15 total locomotion0.91.75.22.3-2.1-2.1-1.2-2.0-2.2-2.20.8-0.80.80.2-0.8-0.0-1.10.50.1-1.80.3-0.90.10.2-1.01.0-0.9
Intermittent access total locomotion1.01.33.71.6-1.6-1.6-0.9-1.9-1.7-1.70.4-0.4-0.50.3-1.3-0.3-1.8-0.50.3-1.6-0.7-1.0-0.2-0.30.1-0.1-1.5
Intermittent access standard deviation0.00.10.20.5-0.3-0.3-0.1-0.3-0.3-0.30.3-0.30.30.3-0.2-0.3-0.30.30.2-0.20.4-0.00.2-0.1-0.00.0-0.0
Left kidney weight1.04.615.71.9-0.2-0.1-3.0-0.5-0.7-0.73.5-3.54.02.6-0.4-2.3-0.13.62.40.33.3-0.22.8-1.90.1-0.31.8
Right kidney weight0.62.814.21.5-0.5-0.4-2.6-0.1-0.8-0.82.6-2.63.81.20.7-0.90.73.01.00.12.60.61.8-0.5-1.31.01.4
Cocaine induced anxiety1.21.75.21.5-1.6-1.6-0.9-2.2-1.6-1.6-0.20.2-0.80.5-2.3-0.5-2.2-0.50.4-1.9-0.3-1.60.1-0.40.8-0.8-1.4
Post-drug Anxiety1.61.74.31.5-1.9-1.9-0.1-1.7-2.0-2.0-0.80.8-0.8-0.8-0.90.8-1.2-1.0-0.9-2.1-0.9-1.0-1.00.9-0.80.8-1.7
Baseline Anxiety1.51.75.3-0.3-0.3-0.31.20.8-0.4-0.4-0.80.8-0.1-1.92.21.91.6-0.8-1.7-0.1-1.11.1-1.61.8-2.32.3-0.5
Tail length1.14.313.02.4-1.1-1.2-3.6-1.7-1.1-1.12.8-2.81.92.4-2.6-2.3-2.02.02.4-0.61.8-2.72.3-2.21.3-1.40.2
Length with tail1.66.919.33.3-1.8-1.8-4.4-2.3-1.9-1.93.8-3.82.93.0-2.8-2.8-2.22.92.9-1.02.5-3.02.9-2.61.0-1.20.3
Length without tail0.61.95.82.1-1.6-1.6-2.4-1.6-1.8-1.81.8-1.81.51.1-1.1-0.9-1.31.21.0-1.20.8-1.21.0-0.7-0.30.2-0.4
Times rat made contact with spout0.60.72.9-0.30.50.20.9-0.60.10.10.4-0.4-1.50.6-1.1-0.8-1.3-0.80.9-0.0-0.9-0.50.2-1.11.6-1.7-0.8
Lifetime Intake1.11.33.31.5-1.7-1.7-1.2-1.8-1.6-1.60.2-0.2-0.70.1-1.3-0.1-1.8-0.70.1-1.7-0.9-1.2-0.3-0.10.0-0.0-1.6
Liver weight, left0.20.30.90.00.30.4-0.60.20.10.10.9-0.90.90.50.4-0.50.10.80.50.40.70.50.6-0.4-0.00.00.5
Liver weight, right0.81.55.4-0.00.90.8-0.20.80.50.51.8-1.82.31.01.1-0.91.12.11.01.11.91.11.4-0.7-0.20.31.6
Locomotor activity1.21.84.50.8-0.3-0.3-0.8-1.1-0.1-0.11.6-1.6-0.41.8-2.0-1.9-2.00.32.0-0.00.1-1.61.2-2.12.1-1.9-0.3
Locomotor testing distance0.71.32.71.5-1.0-1.1-1.5-1.3-1.1-1.11.7-1.70.81.3-1.2-1.2-1.30.91.3-0.80.7-1.11.0-1.10.5-0.4-0.3
Locomotor testing rearing1.22.35.12.1-1.7-1.4-1.7-2.1-1.6-1.61.7-1.70.11.5-2.3-1.5-2.20.41.6-1.30.2-1.80.9-1.51.1-0.7-1.0
Locomotion in novel chamber0.30.41.6-0.60.50.50.40.60.20.2-0.60.6-0.1-0.61.00.60.9-0.3-0.70.1-0.11.3-0.60.7-0.70.6-0.0
Locomotion in novel chamber post-restriction1.01.77.1-1.51.11.12.71.20.90.9-1.51.5-1.5-1.31.51.31.2-1.4-1.30.5-1.21.5-1.41.1-0.60.5-0.1
Fecal boli incidents, locomotor time 10.20.31.3-0.50.50.50.20.00.60.60.2-0.2-0.80.5-0.2-0.5-0.6-0.40.50.3-0.30.50.1-0.60.9-1.1-0.4
Change in fecal boli incidents, locomotor task0.30.30.9-0.70.80.81.00.50.90.9-0.60.6-0.7-0.0-0.1-0.10.2-0.40.00.7-0.4-0.5-0.0-0.20.8-0.50.4
Time >=10cm from walls, locomotor time 11.41.55.2-0.60.40.41.11.0-0.2-0.2-0.80.80.6-1.42.31.62.1-0.0-1.50.10.21.5-1.11.7-2.21.90.2
Bouts of movement, locomotor time 10.60.71.6-0.0-0.4-0.41.10.3-0.3-0.3-1.01.0-0.5-1.20.81.20.7-0.7-1.2-0.3-0.6-1.2-1.11.2-1.20.9-0.1
Total resting periods, locomotor time 10.70.81.80.2-0.5-0.61.30.2-0.3-0.3-1.01.0-0.5-1.20.71.20.7-0.8-1.2-0.4-0.6-1.1-1.21.3-1.21.1-0.2
Rest time, locomotor task time 10.20.30.70.30.10.10.40.10.50.50.8-0.80.20.7-0.2-0.7-0.30.40.70.60.4-0.90.5-0.70.6-0.50.4
Distance moved, locomotor task time 10.10.10.9-0.30.30.4-0.70.1-0.0-0.00.1-0.10.60.10.1-0.10.40.50.1-0.00.40.90.4-0.10.1-0.10.3
Vertical activity count, locomotor time 10.20.61.6-1.30.70.80.30.60.50.5-1.21.2-1.1-0.80.40.70.4-1.0-0.70.1-1.11.1-0.70.50.2-0.2-0.4
Time >=10cm from walls, locomotor time 20.10.20.9-0.60.30.40.70.40.20.2-0.00.0-0.2-0.50.90.40.5-0.2-0.30.3-0.50.7-0.40.3-0.40.3-0.2
Bouts of movement, locomotor time 20.20.31.00.9-0.9-1.00.2-0.7-1.0-1.00.3-0.30.3-0.00.00.1-0.40.1-0.1-0.70.2-0.4-0.20.3-0.80.5-0.3
Total resting periods, locomotor time 20.20.41.31.0-1.0-1.10.6-0.8-1.1-1.10.3-0.30.2-0.10.10.2-0.40.0-0.2-0.80.1-0.5-0.30.4-0.90.7-0.4
Rest time, locomotor task time 20.20.30.8-0.20.70.60.60.60.70.70.7-0.70.40.50.3-0.50.30.50.60.90.3-0.00.5-0.60.5-0.20.6
Distance moved, locomotor task time 20.20.21.0-0.60.30.5-0.20.50.30.3-0.40.40.3-0.30.50.40.80.1-0.40.30.21.0-0.10.4-0.30.00.4
Vertical activity count, locomotor time 20.50.71.9-0.7-0.2-0.10.10.1-0.1-0.1-1.31.3-1.3-1.10.31.00.0-1.4-1.0-0.5-1.30.3-1.10.9-0.40.1-1.0
Light reinforcement 10.61.64.61.5-0.6-0.7-1.4-0.3-0.7-0.72.0-2.02.21.6-0.5-1.5-0.22.01.5-0.11.9-0.41.5-1.20.20.10.9
Light reinforcement 21.52.26.70.70.30.2-1.30.40.30.32.4-2.42.62.0-0.0-1.80.22.51.81.02.40.22.0-1.60.6-0.21.7
Bone: marrow area0.30.61.50.20.40.3-0.7-0.10.20.21.2-1.20.61.2-0.5-1.2-0.30.81.20.40.9-0.61.0-1.10.9-0.90.5
Bone: maximum diameter3.05.513.03.6-2.5-2.5-2.5-2.9-2.5-2.52.9-2.92.02.5-2.8-2.3-2.62.12.3-1.81.9-2.72.2-2.00.8-0.7-0.4
Bone: maximum force1.12.06.50.90.10.1-1.30.10.00.02.2-2.22.51.8-0.2-1.60.32.41.60.62.4-0.41.9-1.30.3-0.21.5
Bone: maximum moment1.32.35.70.90.10.1-1.9-0.10.00.02.3-2.32.42.1-0.7-1.9-0.12.41.90.52.4-0.42.2-1.70.8-0.61.4
Mean time between licks in bursts0.40.93.8-0.70.80.80.10.31.11.10.2-0.2-1.10.8-1.2-1.0-0.6-0.51.00.7-0.5-0.90.5-1.32.0-1.80.1
Mean num. licks in bursts0.71.27.3-1.00.70.42.7-0.10.40.4-1.31.3-2.2-0.90.20.7-0.5-1.7-0.7-0.1-1.60.6-1.10.40.4-0.6-0.8
Cd content in liver0.10.11.30.3-0.3-0.2-0.2-0.10.10.10.1-0.1-0.20.3-0.7-0.3-0.2-0.00.3-0.00.0-1.10.2-0.30.5-0.40.1
Co content in liver0.50.61.71.1-1.2-1.3-0.5-1.3-1.3-1.30.1-0.1-0.10.1-0.7-0.0-0.9-0.2-0.0-1.20.1-0.5-0.10.1-0.30.4-0.9
Cu content in liver0.80.92.0-0.2-0.5-0.50.6-0.1-0.4-0.4-1.31.3-1.2-1.40.41.30.1-1.4-1.3-0.7-1.3-0.0-1.41.2-0.90.8-1.1
Fe content in liver2.22.67.1-1.40.50.52.70.60.30.3-2.52.5-2.2-2.01.51.90.8-2.3-2.0-0.2-1.71.4-2.31.9-1.00.8-1.0
K content in liver2.32.24.91.4-2.1-2.2-1.0-1.4-2.0-2.0-1.01.0-0.7-1.4-0.21.5-1.0-1.3-1.4-2.0-1.3-0.6-1.51.5-1.71.8-1.9
Mg content in liver1.61.74.92.1-2.2-2.2-1.4-1.8-2.1-2.10.2-0.20.3-0.3-0.80.4-1.3-0.1-0.4-1.9-0.3-0.7-0.40.6-1.11.2-1.4
Mn content in liver0.20.20.90.1-0.4-0.2-0.4-0.6-0.5-0.5-0.30.3-0.8-0.3-0.50.2-0.8-0.7-0.1-0.7-0.9-0.3-0.30.00.3-0.2-0.9
Na content in liver4.24.510.52.0-2.8-2.80.4-2.6-2.8-2.8-1.31.3-2.2-1.6-1.11.6-1.8-2.4-1.5-3.1-2.3-1.3-2.11.5-1.31.5-3.2
Rb content in liver0.20.30.90.8-0.9-0.9-0.3-0.6-0.8-0.8-0.10.10.1-0.2-0.00.3-0.3-0.1-0.3-0.70.10.0-0.30.4-0.70.9-0.4
Se content in liver1.21.53.81.5-2.0-1.8-1.8-1.7-1.7-1.7-0.20.2-0.5-0.3-1.30.3-1.6-0.7-0.2-1.7-0.9-1.7-0.40.2-0.20.1-1.6
Sr content in liver2.11.83.82.0-1.2-1.2-1.3-1.6-1.2-1.21.7-1.70.91.4-1.8-1.4-1.51.01.4-1.00.9-1.81.3-1.30.8-0.8-0.4
Zn content in liver1.01.13.10.70.00.0-1.8-0.6-0.1-0.11.3-1.31.11.4-1.2-1.4-0.71.21.40.00.9-0.71.5-1.41.1-1.10.6
Bone: minimum diameter0.61.12.50.40.40.3-1.1-0.10.10.11.6-1.61.41.5-0.6-1.4-0.21.51.40.41.4-0.41.5-1.30.8-0.80.9
Time in familiar zone, hab. session 11.11.12.8-1.51.71.71.11.61.61.6-0.50.50.2-0.11.30.21.50.2-0.21.40.61.1-0.00.20.0-0.01.3
Time in novel zone, hab. session 11.11.13.31.2-1.2-1.2-1.8-1.4-1.1-1.10.9-0.90.30.8-1.5-0.8-1.60.40.9-0.9-0.1-1.10.7-0.90.7-0.7-0.7
Total zone transitions, hab. session 10.20.32.2-0.70.90.71.50.60.80.8-0.20.2-0.6-0.10.50.10.4-0.3-0.00.7-0.50.6-0.2-0.10.3-0.20.3
Total locomotion distance, hab. session 10.30.41.8-0.30.10.00.8-0.20.10.1-0.70.7-1.4-0.5-0.30.4-0.4-1.1-0.4-0.2-1.3-0.0-0.70.20.3-0.2-0.7
Locomotion velocity, hab. session 10.20.31.4-0.20.10.11.2-0.00.10.1-0.70.7-1.2-0.6-0.00.5-0.1-1.0-0.5-0.1-1.10.0-0.80.40.00.1-0.5
Time in familiar zone, hab. session 22.82.96.9-2.61.92.01.72.62.12.1-1.81.8-0.4-1.52.31.42.3-0.6-1.51.9-0.32.0-0.91.3-0.70.61.2
Time in novel zone, hab. session 24.04.07.72.6-1.5-1.7-2.1-2.3-1.7-1.72.8-2.81.62.5-2.4-2.4-2.21.82.4-1.31.7-1.82.1-2.11.2-1.1-0.2
Total zone transitions, hab. session 20.10.20.70.6-0.2-0.20.4-0.4-0.1-0.10.6-0.60.10.5-0.6-0.5-0.40.30.50.00.2-0.80.4-0.50.4-0.10.1
Total locomotion distance, hab. session 20.40.51.60.9-0.4-0.3-0.1-0.8-0.3-0.30.7-0.70.00.9-1.3-0.9-0.90.40.9-0.30.4-1.30.7-0.90.8-0.6-0.1
Locomotion velocity, hab. session 20.30.52.01.0-0.7-0.6-0.1-0.9-0.5-0.50.5-0.5-0.20.6-1.3-0.6-1.00.10.6-0.60.1-1.40.4-0.60.5-0.3-0.4
Novel to familiar place preference ratio1.71.83.81.4-1.7-1.80.9-1.8-1.9-1.9-0.80.8-1.4-0.9-0.90.9-1.2-1.4-0.9-2.0-1.5-1.1-1.20.8-0.70.7-1.9
Novelty place preference1.41.53.51.5-1.7-1.80.6-1.9-1.8-1.8-0.50.5-1.2-0.6-1.10.5-1.4-1.1-0.5-1.8-1.3-1.3-0.80.5-0.40.4-1.7
Time in novel zone, NPP test1.21.33.21.4-1.6-1.70.5-1.8-1.7-1.7-0.20.2-1.0-0.3-1.20.3-1.4-0.9-0.3-1.7-1.0-1.3-0.60.2-0.20.2-1.5
Total zone transitions, NPP test0.10.20.8-0.1-0.0-0.20.40.2-0.0-0.0-0.40.4-0.0-0.50.50.60.4-0.2-0.5-0.0-0.30.9-0.40.6-0.60.9-0.1
Total locomotion distance, NPP test0.40.61.00.0-0.4-0.50.6-0.4-0.6-0.6-1.01.0-0.8-0.90.20.9-0.1-0.9-1.0-0.8-0.90.8-1.00.9-0.70.9-0.9
Locomotion velocity, NPP test0.81.11.90.1-0.6-0.70.7-0.5-0.7-0.7-1.41.4-1.1-1.40.31.4-0.2-1.3-1.4-1.0-1.30.7-1.41.3-1.01.2-1.2
Intraocular pressure0.20.31.40.50.40.31.2-0.2-0.1-0.10.8-0.80.60.6-0.1-0.60.10.70.60.20.8-0.80.6-0.50.1-0.30.6
Delta distance traveled before/after self-admin0.30.31.80.4-0.6-0.60.3-0.0-0.6-0.6-0.40.40.4-0.60.80.60.6-0.1-0.6-0.50.0-0.1-0.60.7-0.91.3-0.2
Delta ambulatory time before/after self-admin0.30.41.1-0.4-0.1-0.10.50.40.00.0-0.90.9-0.3-0.70.90.70.7-0.6-0.7-0.1-0.60.7-0.90.7-0.41.0-0.3
Parametrial fat weight0.81.96.41.5-1.6-1.62.5-1.9-1.6-1.6-0.70.7-1.7-0.7-0.80.7-1.1-1.5-0.7-1.9-1.2-1.4-1.20.7-0.50.7-1.7
Pavlov. Cond. lever latency0.20.20.9-0.2-0.3-0.2-0.4-0.10.10.1-0.60.6-0.90.1-0.6-0.1-0.6-0.80.0-0.1-0.6-0.3-0.3-0.10.6-0.7-0.5
Pavlov. Cond. magazine entry latency0.40.61.6-1.21.11.31.11.01.21.2-0.30.3-0.2-0.20.60.10.80.0-0.01.0-0.30.40.2-0.20.6-0.50.8
Pavlov. Cond. change in total contacts0.50.61.10.9-0.9-0.80.7-1.0-1.0-1.0-0.20.2-0.6-0.7-0.30.7-0.6-0.6-0.6-1.1-0.9-0.8-0.60.5-0.60.6-1.0
Pavlov. Cond. index score0.40.51.6-0.90.90.91.30.80.70.7-0.40.4-0.1-0.81.10.71.0-0.1-0.60.6-0.40.7-0.30.5-0.40.50.5
Pavlov. Cond. latency score0.30.41.2-0.80.91.01.10.80.70.7-0.20.20.3-0.61.10.51.10.2-0.40.7-0.00.7-0.10.4-0.40.50.7
Pavlov. Cond. lever contacts0.20.20.8-0.20.60.50.70.40.20.20.3-0.30.7-0.30.90.30.80.5-0.20.40.30.60.10.3-0.60.80.6
Pavlov. Cond. magazine entry number0.40.63.21.0-0.7-0.9-1.8-0.6-0.7-0.70.8-0.81.00.8-0.6-0.7-0.60.70.6-0.41.0-0.60.6-0.4-0.10.0-0.0
Pavlov. Cond. intertrial magazine entries0.30.41.90.9-0.8-0.9-1.4-0.8-1.1-1.10.5-0.50.60.2-0.3-0.1-0.50.30.1-0.80.20.20.10.0-0.50.5-0.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-0.90.91.01.10.80.70.7-0.30.30.1-0.71.10.61.10.1-0.50.7-0.30.8-0.20.4-0.40.50.6
Pavlov. Cond. response bias0.10.20.7-0.30.20.30.80.0-0.0-0.0-0.40.4-0.5-0.70.40.60.2-0.5-0.5-0.1-0.80.3-0.50.4-0.30.4-0.3
Pavlov. Cond. lever latency0.40.54.81.1-1.2-0.9-2.2-0.4-0.6-0.60.4-0.40.70.1-0.6-0.0-0.10.40.0-0.50.2-0.90.10.1-0.40.5-0.2
Pavlov. Cond. magazine entry latency0.10.10.50.5-0.3-0.40.3-0.1-0.2-0.20.6-0.60.70.30.2-0.20.10.60.20.00.60.20.3-0.1-0.30.40.2
Pavlov. Cond. change in total contacts0.10.22.3-0.40.60.31.50.20.20.2-0.00.00.00.10.6-0.00.20.1-0.00.20.30.9-0.00.1-0.10.10.3
Pavlov. Cond. index score0.10.22.0-0.50.60.41.40.30.30.3-0.00.00.00.10.5-0.10.20.20.00.40.30.60.1-0.00.1-0.00.4
Pavlov. Cond. latency score0.20.21.9-0.60.70.41.40.40.40.4-0.00.00.00.10.6-0.10.30.20.00.50.30.70.1-0.10.1-0.00.5
Pavlov. Cond. lever contacts0.50.75.5-1.31.20.92.30.50.60.6-0.80.8-1.0-0.50.80.40.2-0.7-0.40.4-0.51.1-0.50.30.2-0.20.0
Pavlov. Cond. magazine entry number0.40.51.3-0.3-0.1-0.1-0.0-0.2-0.3-0.3-1.11.1-1.1-0.9-0.00.9-0.1-1.2-0.9-0.6-1.1-0.0-1.00.8-0.30.3-0.8
Pavlov. Cond. intertrial magazine entries0.20.30.9-0.10.00.1-0.1-0.6-0.4-0.4-0.50.5-1.0-0.4-0.40.3-0.6-0.9-0.3-0.7-0.8-0.1-0.50.20.1-0.3-0.9
Pavlov. Cond. lever-magazine prob. diff.0.20.21.9-0.60.80.61.40.50.50.50.1-0.10.10.10.7-0.10.30.30.10.50.30.80.2-0.10.1-0.00.5
Pavlov. Cond. response bias0.20.32.9-0.70.80.61.70.30.30.3-0.20.2-0.4-0.20.70.20.1-0.2-0.20.3-0.10.9-0.20.10.0-0.10.1
Time in closed arm before self-admin1.31.63.9-0.51.11.1-1.40.71.21.21.0-1.01.61.5-0.3-1.50.41.71.41.32.00.11.6-1.31.3-1.11.9
Time in closed arm after self-admin1.11.24.1-1.61.71.7-0.31.51.51.5-0.30.30.70.21.0-0.21.40.60.11.30.92.00.5-0.20.5-0.21.3
Time in open arm before self-admin0.00.00.20.0-0.0-0.0-0.10.30.10.10.3-0.3-0.0-0.20.00.20.20.0-0.10.2-0.4-0.20.00.1-0.40.2-0.0
Time in open arm after self-admin0.70.72.61.5-1.3-1.40.3-1.2-1.3-1.31.0-1.00.30.3-0.5-0.3-0.80.30.3-1.00.1-1.60.2-0.2-0.40.4-0.5
Bone: periosteal estimation1.12.35.61.8-0.8-0.9-1.9-1.1-0.9-0.92.4-2.42.11.9-1.2-1.8-0.82.11.8-0.31.9-1.31.9-1.50.5-0.50.6
Bone: periosteal perimeter1.62.77.72.8-2.0-2.0-1.8-2.1-2.1-2.11.9-1.91.71.3-1.7-1.2-1.51.51.2-1.51.4-1.81.2-0.9-0.20.4-0.4
Bone: post-yield work0.10.20.9-0.40.30.3-0.4-0.10.20.20.1-0.1-0.50.5-0.5-0.6-0.6-0.20.50.1-0.30.70.3-0.60.9-0.7-0.2
Progressive ratio test 1 active lever presses1.72.25.31.2-1.9-1.9-0.2-1.9-1.9-1.9-0.80.8-1.7-1.0-0.71.0-1.6-1.8-0.9-2.1-2.1-1.0-1.50.9-0.70.7-2.3
Progressive ratio test 1 breakpoint1.82.25.41.3-2.0-1.9-0.2-1.9-1.9-1.9-0.80.8-1.7-1.1-0.71.0-1.6-1.8-1.0-2.1-2.1-1.0-1.50.9-0.80.8-2.3
Progressive ratio test 1 inactive lever presses1.72.57.02.1-2.5-2.5-0.4-2.6-2.3-2.3-0.30.3-1.1-0.2-1.70.3-2.2-1.1-0.3-2.4-1.0-1.5-0.80.4-0.40.4-2.1
Progressive ratio test 2 active lever presses0.70.82.21.1-1.4-1.4-0.3-1.3-1.4-1.4-0.40.4-0.4-0.4-0.60.4-1.0-0.6-0.5-1.5-0.6-0.9-0.60.5-0.50.5-1.0
Progressive ratio test 2 breakpoint0.60.71.91.1-1.3-1.3-0.3-1.2-1.3-1.3-0.40.4-0.3-0.3-0.50.4-0.8-0.5-0.4-1.4-0.4-0.8-0.50.5-0.50.5-0.9
Progressive ratio test 2 inactive lever presses1.21.96.82.6-2.2-2.2-0.6-2.2-2.2-2.20.9-0.90.90.6-1.2-0.4-1.30.60.3-1.80.8-1.70.3-0.0-0.80.8-0.6
Incentive Sensitization - Responses0.20.20.80.7-0.6-0.5-0.1-0.3-0.6-0.60.1-0.10.90.10.10.00.20.6-0.1-0.50.8-0.40.20.3-0.70.70.4
Incentive Sensitization - Breakpoint0.20.31.20.7-0.4-0.4-0.2-0.2-0.5-0.50.3-0.31.10.30.1-0.10.20.80.0-0.41.1-0.40.40.2-0.60.60.6
Sum of active levers in priming session hrs 5-61.51.42.70.5-1.2-1.2-0.0-0.8-1.3-1.3-1.01.0-0.7-1.60.31.6-0.1-1.1-1.5-1.3-1.60.2-1.31.4-1.41.6-1.3
Progressive ratio0.10.10.50.10.20.0-0.3-0.2-0.3-0.30.7-0.70.40.30.1-0.30.10.40.4-0.10.40.00.3-0.3-0.0-0.2-0.2
Food seeking constrained by brief footshock1.11.33.51.9-1.7-1.7-1.4-1.6-1.8-1.81.1-1.10.80.2-0.6-0.2-0.90.40.4-1.4-0.2-1.40.2-0.3-0.40.8-1.0
Seeking ratio, punishment vs. effort0.30.51.71.2-1.1-1.1-0.8-1.0-0.9-0.90.2-0.20.30.3-1.0-0.3-1.00.20.2-0.80.0-1.30.2-0.20.20.1-0.2
Retroperitoneal fat weight0.20.94.41.5-1.1-1.12.1-0.8-1.3-1.30.1-0.10.2-0.50.40.60.20.0-0.6-1.10.3-1.0-0.70.8-1.51.5-0.4
Reaction time number correct1.83.49.30.01.11.0-1.1-0.30.80.82.2-2.20.72.8-1.8-2.9-1.21.52.90.81.5-0.52.3-3.03.1-2.50.9
Reaction time mean minus median0.10.31.1-0.3-0.1-0.10.1-0.2-0.1-0.1-1.01.0-1.0-0.6-0.30.6-0.6-0.9-0.6-0.3-0.9-0.0-0.60.5-0.1-0.2-0.7
Reaction time mean minus median AUC0.10.20.60.6-0.7-0.8-0.3-0.5-0.6-0.6-0.10.10.2-0.1-0.20.2-0.40.1-0.3-0.50.1-0.1-0.10.3-0.50.5-0.3
Reaction time num false alarms0.81.24.31.1-1.3-1.30.4-0.5-1.3-1.3-0.50.50.7-1.11.01.30.70.0-1.3-1.0-0.10.6-0.91.5-2.12.0-0.3
Reaction time num false alarms AUC0.71.04.51.0-1.0-1.10.2-0.1-1.1-1.1-0.20.21.3-0.91.31.11.10.6-1.1-0.70.50.7-0.51.4-2.11.90.2
Reaction time trials correct on left1.83.49.30.01.11.0-1.1-0.30.80.82.2-2.20.72.8-1.8-2.9-1.21.52.90.81.5-0.52.3-3.03.1-2.50.9
Reaction time trials on left1.73.39.3-0.01.11.0-1.0-0.30.80.82.2-2.20.72.8-1.7-2.9-1.21.42.90.81.4-0.52.3-3.03.0-2.50.9
Reaction time mean0.60.92.8-0.80.00.10.30.50.10.1-1.71.7-0.9-1.40.71.40.4-1.1-1.4-0.2-1.00.6-1.21.3-0.80.7-0.6
Reaction time mean AUC0.50.72.4-0.80.10.20.20.50.20.2-1.61.6-0.7-1.20.71.20.4-1.0-1.3-0.1-0.80.7-1.11.2-0.70.7-0.4
Median of all reaction times0.71.02.9-1.00.20.30.40.70.20.2-1.71.7-0.8-1.51.01.50.8-1.1-1.5-0.1-1.00.7-1.31.4-1.00.9-0.4
Reaction time omissions0.10.20.6-0.40.40.40.80.10.10.1-0.60.6-0.6-0.40.20.40.0-0.5-0.50.0-0.30.6-0.50.4-0.10.2-0.2
Reaction time false alarm rate2.02.711.61.0-1.5-1.50.4-0.1-1.5-1.5-1.11.11.0-2.11.92.31.5-0.1-2.3-1.1-0.20.8-1.52.6-3.42.9-0.3
Reaction time premature initiation rate1.41.95.4-1.61.81.81.42.31.91.9-0.00.00.9-0.32.00.32.20.7-0.32.10.71.50.20.4-0.60.51.9
Reaction time premature initiations1.11.94.3-1.32.01.90.61.71.91.91.0-1.01.01.20.7-1.21.11.31.22.11.30.91.3-1.21.0-0.92.0
Std. dev. reaction times0.20.41.3-0.4-0.1-0.00.40.20.00.0-1.21.2-0.6-0.90.30.90.1-0.7-1.0-0.1-0.50.5-0.71.0-0.70.4-0.3
Reaction time trials completed1.73.39.3-0.01.11.0-1.0-0.30.80.82.2-2.20.72.8-1.7-2.9-1.21.42.90.81.4-0.52.3-3.03.0-2.50.9
Reaction time trials AUC1.73.39.40.01.00.9-1.2-0.40.70.72.1-2.10.62.8-1.9-2.9-1.31.42.80.71.3-0.52.3-3.03.1-2.50.8
Run reversals in cocaine runway, females3.13.16.6-1.20.30.32.11.20.30.3-2.02.0-0.7-2.42.62.52.2-1.3-2.40.1-1.32.1-2.12.4-2.32.3-0.3
Run reversals in cocaine runway, males0.10.10.40.30.00.0-0.4-0.2-0.0-0.00.4-0.40.40.3-0.5-0.4-0.20.50.4-0.10.0-0.60.5-0.50.6-0.40.3
Latency to leave start box in cocaine runway0.30.30.90.4-0.8-0.70.6-0.2-0.5-0.50.2-0.2-0.4-0.60.50.60.2-0.6-0.4-0.3-0.9-0.1-0.70.4-0.70.8-0.6
Latency to leave start box in cocaine runway, F0.50.61.61.2-0.9-0.9-0.3-0.3-0.7-0.71.2-1.21.30.10.2-0.00.41.00.2-0.20.7-0.80.4-0.0-0.90.90.3
Latency to leave start box in cocaine runway, M1.11.04.7-0.4-0.5-0.51.1-0.3-0.2-0.2-1.01.0-2.2-0.80.10.6-0.7-2.0-0.6-0.5-2.10.5-1.50.40.20.1-1.6
Std. dev. time between licks in bursts0.40.61.8-1.21.11.30.61.11.41.4-0.10.1-0.60.00.3-0.10.8-0.30.21.2-0.4-0.50.0-0.40.7-0.70.7
Total sessions with >9 infusions0.00.10.20.1-0.2-0.20.2-0.4-0.2-0.2-0.10.1-0.4-0.0-0.10.0-0.4-0.3-0.0-0.3-0.30.2-0.20.00.1-0.1-0.4
Short access day 1 total inactive lever presses1.72.24.62.2-1.6-1.6-1.5-2.1-1.6-1.61.7-1.70.41.5-2.0-1.4-2.10.61.5-1.30.4-2.01.0-1.40.8-0.8-1.0
Short access day 10 total inactive lever presses0.71.83.81.2-0.4-0.4-1.3-1.1-0.5-0.51.8-1.80.82.0-1.8-1.9-1.41.21.9-0.41.1-1.11.7-1.81.5-1.50.2
Short access day 1 total infusions0.00.00.10.2-0.1-0.2-0.2-0.2-0.2-0.20.3-0.30.10.00.20.0-0.00.00.0-0.1-0.10.3-0.10.0-0.20.2-0.2
Short access day 10 total infusions0.10.10.5-0.30.10.10.40.10.10.1-0.30.3-0.7-0.30.20.3-0.1-0.6-0.2-0.0-0.70.4-0.50.2-0.10.1-0.4
Short access total infusions0.10.20.60.4-0.5-0.5-0.4-0.7-0.5-0.50.2-0.2-0.40.1-0.5-0.2-0.8-0.40.2-0.6-0.5-0.4-0.1-0.20.2-0.2-0.7
Short access day 1 locomotion0.50.61.2-0.61.11.0-0.40.60.80.80.7-0.70.60.80.1-0.90.30.80.90.90.60.60.9-0.90.9-0.90.7
Short access day 10 total locomotion0.71.23.7-1.91.71.71.01.01.71.7-0.70.7-1.4-0.00.4-0.20.3-0.90.21.3-1.01.5-0.2-0.51.3-1.30.2
Short access total locomotion0.91.02.7-1.41.71.60.50.91.51.50.2-0.2-0.50.70.0-0.90.10.00.91.3-0.11.00.6-1.11.6-1.60.7
One hour access (0.3 mA shock)0.80.92.50.9-1.1-1.1-0.4-1.4-1.4-1.4-0.30.3-1.1-0.3-0.80.3-1.3-1.1-0.2-1.6-1.2-0.6-0.70.2-0.10.1-1.6
Compulsive drug intake1.72.05.0-2.11.51.51.51.91.41.4-1.11.1-0.9-1.52.21.41.8-1.1-1.21.1-1.42.1-1.31.1-0.70.70.1
One hour access (shock baseline)1.52.36.12.0-2.2-2.2-1.3-2.5-2.2-2.20.0-0.0-0.90.3-2.0-0.2-2.4-0.90.2-2.2-0.8-1.7-0.4-0.10.2-0.2-1.9
Social response proportion0.50.62.4-0.40.70.7-0.20.10.70.70.1-0.1-0.30.9-1.2-1.0-0.60.20.90.50.5-1.00.8-1.01.5-1.50.5
Social responses0.81.02.80.30.40.4-0.6-0.7-0.1-0.11.0-1.0-0.11.5-1.6-1.5-1.20.41.5-0.10.6-1.21.1-1.51.7-1.50.1
Social time0.50.72.6-1.61.51.60.50.91.11.1-1.21.2-0.8-0.30.10.20.4-0.5-0.30.6-0.10.5-0.20.10.7-0.70.4
Soleus weight2.36.815.62.3-0.7-0.7-4.0-1.4-0.6-0.63.9-3.93.23.6-2.4-3.4-1.73.43.4-0.13.0-1.43.5-3.11.8-1.81.4
Bone: stiffness0.20.31.30.3-0.3-0.30.7-0.0-0.4-0.40.2-0.20.7-0.20.90.40.60.4-0.4-0.20.50.7-0.20.5-1.11.20.1
Tibialis anterior weight1.03.48.62.9-2.3-2.3-2.3-2.3-2.0-2.02.3-2.31.51.7-2.0-1.5-2.01.51.6-1.61.2-1.81.5-1.30.2-0.2-0.5
Time to tail flick, vehicle, before self-admin0.60.61.8-0.40.20.20.40.50.10.1-1.21.20.8-0.71.00.81.20.3-1.0-0.10.91.0-0.41.1-1.01.30.7
Time to tail flick, vehicle, after self-admin1.21.63.3-0.7-0.2-0.21.80.50.10.1-1.61.6-1.6-1.61.11.60.7-1.7-1.6-0.3-1.51.7-1.81.5-1.11.6-1.2
Time to tail flick, test, before self-admin0.30.32.60.00.50.4-0.3-0.30.10.10.3-0.30.10.7-0.6-0.7-0.60.30.6-0.00.6-0.70.6-0.50.6-1.60.2
Time to tail flick, test, after self-admin3.23.37.81.9-1.1-1.1-2.2-2.4-1.4-1.41.9-1.91.02.3-2.8-2.2-2.51.42.1-1.31.3-1.12.0-2.11.7-1.8-0.1
Delta time to tail flick, vehicle, before/after SA0.90.84.2-0.4-0.1-0.21.40.10.10.1-0.30.3-1.9-0.90.40.7-0.2-1.7-0.5-0.1-2.10.7-1.30.4-0.20.4-1.5
Delta time to tail flick, test, before/after SA0.80.82.01.1-1.0-0.9-1.1-1.2-0.7-0.71.1-1.10.31.0-1.4-1.1-1.30.61.1-0.60.3-0.30.9-1.11.0-0.3-0.2
Tibia length0.41.14.3-0.30.70.8-1.01.20.60.60.8-0.82.10.31.2-0.21.51.60.21.01.51.30.80.0-0.70.71.6
Ambulatory time before self-admin0.81.23.4-0.6-0.1-0.00.70.2-0.2-0.2-1.31.3-1.7-1.50.61.40.0-1.8-1.4-0.4-1.90.6-1.51.3-0.90.6-1.5
Ambulatory time after self-admin1.61.84.3-1.0-0.2-0.11.10.50.10.1-1.91.9-1.9-1.81.21.70.5-2.1-1.7-0.3-2.01.2-2.01.5-0.91.2-1.4
Bone: tissue strength2.92.96.0-0.21.51.5-1.50.31.01.02.2-2.21.62.4-0.8-2.4-0.32.02.41.32.10.12.4-2.32.0-1.81.5
Total heroin consumption0.20.20.8-0.40.60.5-0.40.20.30.30.9-0.90.30.40.2-0.4-0.00.40.50.40.1-0.10.4-0.50.2-0.8-0.0
Bone: trabecular number0.20.30.8-0.90.70.6-0.60.80.70.7-0.50.5-0.5-0.60.40.50.4-0.5-0.40.6-0.7-0.1-0.40.30.10.1-0.1
Bone: trabecular spacing0.70.91.71.3-0.6-0.6-0.2-1.0-0.7-0.71.3-1.30.91.3-1.1-1.2-0.81.11.1-0.41.2-1.11.1-1.00.5-0.70.3
Bone: trabecular thickness0.81.03.4-1.81.41.4-0.41.61.31.3-0.80.8-0.3-0.91.30.81.2-0.5-0.71.1-0.81.3-0.50.5-0.10.10.5
Bone: trabecular tissue density0.30.51.3-0.60.20.21.1-0.0-0.2-0.2-0.80.8-0.8-0.90.80.90.4-0.9-0.9-0.5-1.01.0-0.90.8-0.70.4-0.7
Water consumed over 24 hours1.21.76.3-0.91.31.2-0.10.21.11.11.0-1.0-0.51.6-1.2-1.8-0.90.31.81.00.2-0.11.3-2.02.5-2.50.5
Number of responses in last shaping day1.31.43.3-0.2-0.4-0.41.80.1-0.4-0.4-1.31.3-0.8-1.61.41.60.7-1.2-1.6-0.5-1.11.2-1.61.7-1.71.7-0.6