Hub : Genes

Smtn

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Smtn 0.12 0.06 3.6e-06 0.05 0.06 0.05 0.06 3.0e-05 1.3e-06 1.9e-05 2.2e-06
2 Adipose gene expression Smtn 0.05 0.03 2.0e-03 0.02 0.02 0.02 0.02 1.2e-03 4.4e-03 1.6e-03 1.9e-03
3 Adipose intron excision ratio chr14_82634918_82635013 0.07 0.04 8.2e-06 0.04 0.04 0.04 0.04 9.7e-06 2.9e-05 5.9e-05 4.5e-05
4 Eye intron excision ratio chr14_82635084_82635686 0.58 0.15 3.5e-04 0.08 0.2 0.14 0.19 2.2e-02 5.2e-04 3.7e-03 7.6e-04
5 Brain gene expression Smtn 0.67 0.06 0.0e+00 0.47 0.45 0.47 0.48 1.0e-48 1.4e-46 2.2e-49 2.4e-50
6 Brain intron excision ratio chr14_82634918_82635013 0.04 0.03 4.2e-03 0.02 0.01 0.01 0.01 4.7e-03 4.2e-02 3.3e-02 4.3e-02
7 Liver intron excision ratio chr14_82634918_82635013 0.06 0.03 4.9e-04 0.04 0.02 0.03 0.03 2.7e-05 9.0e-04 1.2e-04 1.1e-04
8 Liver intron excision ratio chr14_82627382_82627585 0.04 0.02 2.4e-04 0.03 0.02 0.03 0.03 1.2e-04 1.1e-03 7.4e-04 7.8e-04
9 Liver intron excision ratio chr14_82627385_82627585 0.04 0.02 2.7e-04 0.03 0.02 0.02 0.03 1.2e-04 1.2e-03 5.9e-03 7.5e-04
10 Liver gene expression Smtn 0.13 0.06 1.7e-10 0.05 0.09 0.09 0.05 2.1e-06 5.6e-10 1.0e-09 2.2e-06
11 OFC alternative polyA XM_063272944.1 0.13 0.08 8.3e-03 0.05 0.06 0.06 0.07 2.5e-02 1.6e-02 1.4e-02 7.7e-03
12 BLA intron excision ratio chr14_82634918_82635013 0.14 0.09 7.8e-03 0 0.02 -0 0.01 2.0e-01 4.4e-02 3.9e-01 8.7e-02
13 OFC alternative polyA XM_017599120.3 0.15 0.09 3.8e-03 0.06 0.08 0.09 0.1 1.4e-02 5.7e-03 4.7e-03 2.7e-03
14 NAcc gene expression Smtn 0.06 0.03 6.5e-05 0.03 0.02 0.02 0.03 4.5e-05 2.1e-04 1.2e-04 4.3e-05
15 Brain alternative TSS XM_008770259.4 0.03 0.02 9.5e-03 0 0.02 0 0.01 1.1e-01 7.4e-03 2.4e-01 5.9e-02
16 OFC alternative polyA XM_063272944.1 0.14 0.08 5.7e-03 0.05 0.07 0.05 0.09 2.1e-02 9.6e-03 2.3e-02 4.5e-03
17 NAcc intron excision ratio chr14_82634918_82635013 0.04 0.03 7.7e-04 0.02 0.02 0.02 0.02 9.6e-04 3.5e-04 8.6e-04 3.5e-04
18 BLA gene expression Smtn 0.14 0.08 5.8e-03 0.04 0.01 0.05 0.01 3.0e-03 1.4e-01 1.9e-03 7.1e-02
19 LHb gene expression Smtn 0.54 0.14 5.9e-11 0.24 0.35 0.44 0.41 2.5e-06 4.3e-09 7.9e-12 7.1e-11
20 LHb alternative TSS XM_017599120.3 0.12 0.08 1.0e-02 0.04 0.05 0.02 0.04 4.0e-02 2.8e-02 9.0e-02 4.1e-02
21 OFC alternative polyA XM_017599120.3 0.14 0.08 4.8e-03 0.09 0.07 0.06 0.09 4.4e-03 7.7e-03 1.5e-02 3.3e-03
22 Liver isoform ratio XM_006251196.5 0.03 0.02 3.3e-04 0.03 0.02 0.02 0.02 1.3e-04 1.1e-03 6.0e-03 1.2e-03
23 pVTA gene expression Smtn 0.07 0.05 5.9e-03 0.04 0.04 0.02 0.03 4.9e-04 6.0e-04 8.5e-03 1.9e-03
24 pVTA intron excision ratio chr14_82634918_82635013 0.22 0.1 5.8e-06 0.08 0.07 0.07 0.07 3.9e-07 2.0e-06 2.8e-06 2.8e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.40.72.2-1.5-1.2-1.1-0.01.0-1.0-1.00.8-0.8-1.1-0.80.60.60.4-1.0-0.50.7-0.21.3-0.60.3-0.30.40.2
Area under the delay curve3.04.513.13.13.63.6-0.7-2.93.53.5-0.00.0-0.2-0.9-1.11.1-1.6-0.7-1.0-3.32.10.9-1.21.22.0-2.12.3
BMI with tail0.51.95.42.32.02.00.5-1.52.12.1-0.80.81.6-0.30.40.6-0.01.0-0.5-1.70.2-1.0-0.11.02.3-2.20.2
BMI without tail0.21.36.21.50.70.7-0.3-0.30.60.6-1.51.52.50.60.4-0.40.72.10.4-0.10.3-2.11.1-0.01.3-1.2-1.3
Body weight1.56.421.84.73.43.5-2.2-3.23.83.8-2.82.83.11.2-1.3-0.8-1.42.30.9-2.72.4-2.11.2-0.32.0-1.80.6
Weight adjusted by age0.51.54.72.21.71.7-1.1-1.11.21.2-1.81.81.51.0-0.7-0.9-0.71.20.9-0.61.4-1.10.8-0.60.5-0.6-0.0
Bone surface0.10.10.70.10.10.2-0.1-0.00.20.20.1-0.1-0.3-0.50.10.50.0-0.4-0.3-0.10.80.7-0.40.30.3-0.40.4
Bone volume0.10.10.7-0.4-0.4-0.3-0.30.3-0.2-0.20.2-0.2-0.4-0.50.20.40.1-0.5-0.20.20.50.9-0.30.1-0.0-0.00.3
Breakpoint value in progressive ratio session0.20.31.10.40.50.6-0.2-0.70.90.9-0.10.1-0.4-0.5-0.10.6-0.5-0.5-0.4-0.80.80.8-0.40.50.8-0.01.0
Number of licking bursts0.31.14.90.80.30.2-2.2-0.20.20.2-1.51.51.31.3-0.9-1.2-0.41.31.30.11.0-1.11.3-1.2-0.60.6-0.4
Context. condit. distance diff. score0.91.12.8-1.6-1.5-1.21.41.7-1.4-1.40.4-0.4-0.1-0.51.50.51.5-0.1-0.41.3-1.4-0.0-0.30.40.3-0.4-0.9
Locomotion velocity, session 10.30.31.8-0.30.10.11.30.0-0.3-0.30.5-0.5-1.3-0.1-0.30.0-0.5-0.9-0.00.20.30.8-0.5-0.1-0.60.50.4
Locomotion distance, session 10.50.61.4-1.2-0.7-0.61.11.2-1.1-1.10.8-0.8-0.6-0.70.90.71.0-0.5-0.61.0-0.60.6-0.60.50.1-0.2-0.4
Locomotion velocity, session 21.31.68.8-1.4-0.9-0.60.9-0.1-0.7-0.71.2-1.2-3.0-0.2-1.1-0.1-1.3-2.20.10.20.22.1-0.8-0.5-1.91.81.3
Locomotion distance, session 21.82.68.5-2.2-1.6-1.42.91.5-1.4-1.42.0-2.0-1.9-1.71.71.51.4-1.7-1.50.9-1.91.6-1.61.30.4-0.40.1
Locomotion velocity, session 30.50.51.5-0.8-0.5-0.41.20.9-0.5-0.50.8-0.8-0.5-0.91.10.90.9-0.5-0.80.5-0.90.5-0.80.80.6-0.7-0.1
Locomotion distance, session 30.30.30.90.80.90.80.8-0.60.70.70.2-0.2-0.5-0.3-0.30.4-0.5-0.5-0.4-0.70.40.4-0.50.40.5-0.60.7
Stereotopy head waving bouts, day 30.60.71.9-1.3-1.2-1.40.41.2-1.3-1.3-0.10.1-0.10.40.5-0.40.60.10.41.3-0.8-0.30.3-0.5-0.70.9-0.8
Stereotopy head waving duration, day 31.11.43.8-1.7-1.7-1.91.21.9-1.9-1.90.2-0.20.20.11.3-0.11.50.30.01.9-1.1-0.60.2-0.0-0.20.4-1.5
Locomotion velocity, session 70.40.41.60.80.40.50.2-1.20.90.9-0.80.8-0.40.6-0.7-0.6-1.0-0.20.7-0.8-0.10.30.2-0.7-0.50.40.9
Locomotion distance, session 70.50.72.6-0.7-0.3-0.41.60.3-0.2-0.20.8-0.8-1.1-0.91.00.90.5-1.1-0.80.0-1.11.1-1.10.80.6-0.70.6
Stereotopy head waving bouts, day 70.20.31.20.80.50.40.2-0.20.60.6-0.70.70.7-0.10.60.20.40.4-0.1-0.30.1-0.4-0.10.31.0-1.1-0.0
Stereotopy head waving duration, day 70.30.41.30.80.30.2-0.00.10.40.4-0.90.91.10.10.70.00.70.80.1-0.00.1-0.80.20.21.0-1.1-0.4
Locomotion velocity, session 81.11.34.1-2.0-2.0-1.51.41.4-1.8-1.80.5-0.5-1.3-0.10.5-0.10.3-0.80.21.5-0.60.8-0.2-0.5-1.31.3-0.4
Locomotion distance, session 83.14.612.4-3.5-3.3-3.02.73.3-3.2-3.21.2-1.2-0.7-0.92.60.72.8-0.4-0.72.8-2.60.2-0.50.5-0.20.1-1.8
Degree of sensitization distance1.61.75.7-2.4-2.4-2.30.81.8-2.0-2.00.4-0.4-0.40.01.2-0.21.2-0.10.21.8-2.00.10.1-0.3-0.80.8-1.1
Degree of sensitization stereotypy0.30.41.31.00.50.5-0.3-0.30.70.7-0.80.81.00.10.40.00.40.70.0-0.30.2-0.60.10.21.0-1.1-0.1
Conditioned locomotion1.31.54.0-0.7-0.3-0.21.11.0-0.2-0.21.2-1.2-0.0-1.82.01.81.7-0.6-1.70.3-1.30.7-1.31.71.8-1.8-0.0
Cocaine response after cond. corrected0.50.71.30.51.11.0-0.7-0.70.70.71.1-1.1-1.0-0.7-0.70.7-0.7-1.1-0.8-0.91.00.9-0.90.70.3-0.41.0
Cocaine response after cond. not corrected0.81.13.21.21.81.7-1.7-1.31.21.20.6-0.6-0.5-0.2-1.40.3-1.2-0.7-0.4-1.31.60.6-0.40.40.2-0.31.1
Cocaine response before conditioning0.60.71.50.90.80.8-1.2-0.80.50.5-1.01.00.71.0-1.1-1.0-0.70.81.0-0.40.7-0.61.0-0.9-0.60.5-0.1
Saline control response0.10.12.2-0.3-0.3-0.21.50.0-0.2-0.20.2-0.2-0.7-0.10.10.10.0-0.4-0.00.1-0.30.4-0.2-0.1-0.30.10.1
Bone: connectivity density0.30.51.0-1.0-0.6-0.50.30.8-0.7-0.70.9-0.9-0.8-0.90.60.80.6-0.9-0.80.5-0.20.9-0.80.60.2-0.20.1
Bone: cortical apparent density0.20.31.10.10.30.30.20.30.30.3-0.10.10.7-0.60.90.70.80.4-0.5-0.1-0.30.0-0.20.61.1-1.0-0.2
Bone: cortical area2.33.89.83.12.12.1-2.4-2.12.22.2-2.52.52.71.8-1.6-1.5-1.32.41.5-1.41.7-2.21.9-1.10.3-0.3-0.2
Bone: cortical porosity0.30.30.90.40.60.6-0.5-0.70.60.60.6-0.6-0.8-0.2-0.80.2-0.8-0.8-0.2-0.70.70.6-0.50.2-0.10.20.9
Bone: cortical porosity0.00.00.10.20.30.2-0.3-0.20.20.20.3-0.3-0.2-0.1-0.20.1-0.2-0.2-0.2-0.20.3-0.0-0.20.20.10.00.3
Bone: cortical thickness1.62.77.72.71.91.9-2.1-1.62.02.0-2.02.02.81.2-0.9-0.9-0.62.30.9-1.30.9-2.11.4-0.50.9-0.9-0.3
Bone: cortical thickness1.01.34.6-0.50.10.10.61.5-0.6-0.60.7-0.71.1-1.21.91.32.10.5-1.30.8-1.0-0.5-0.61.41.8-1.8-1.2
Bone: cortical tissue density0.20.31.20.20.30.40.20.20.30.3-0.00.00.7-0.70.90.70.80.3-0.6-0.1-0.20.1-0.30.71.1-1.0-0.2
Condit. Reinf. active minus inactive responses0.60.62.00.30.40.41.4-0.60.60.61.1-1.1-1.2-0.8-0.20.8-0.2-1.1-0.9-0.80.50.9-1.00.80.4-0.40.9
Condit. Reinf. active-inactive response ratio0.91.05.8-0.6-0.3-0.42.40.1-0.2-0.21.5-1.5-1.7-1.00.11.00.3-1.5-1.0-0.20.11.1-1.20.90.2-0.00.5
Condit. Reinf. active responses0.10.10.90.10.0-0.11.0-0.10.20.20.6-0.6-0.4-0.4-0.10.40.2-0.4-0.4-0.20.40.3-0.40.40.2-0.30.2
Condit. Reinf. inactive responses0.60.82.50.60.2-0.1-1.6-0.10.10.1-1.31.31.51.0-0.4-1.0-0.21.41.00.20.4-1.11.2-0.9-0.40.1-0.6
Incentive salience index mean0.50.61.51.11.00.90.6-1.21.21.20.3-0.3-0.6-0.4-0.70.4-0.7-0.5-0.4-1.21.20.6-0.50.40.4-0.51.0
Condit. Reinf. lever presses0.40.62.41.51.31.0-0.3-1.11.21.2-0.70.70.70.1-0.60.0-0.50.50.1-0.91.2-0.30.20.10.6-0.80.4
Condit. Reinf. active minus inactive responses0.50.81.5-0.2-0.7-0.7-0.00.3-0.7-0.7-1.11.10.81.2-0.3-1.2-0.01.11.20.9-0.3-1.11.2-1.2-1.00.9-1.1
Condit. Reinf. active-inactive response ratio0.10.20.60.20.50.20.8-0.30.30.30.5-0.5-0.4-0.60.20.60.1-0.5-0.6-0.40.10.6-0.60.60.6-0.60.3
Condit. Reinf. active responses0.30.51.3-0.8-1.2-0.91.10.4-0.9-0.9-0.30.3-0.10.60.1-0.70.00.30.70.8-0.9-0.30.6-0.7-0.90.9-0.7
Condit. Reinf. inactive responses0.50.82.8-1.2-1.7-1.31.00.8-1.2-1.2-0.20.2-0.00.60.3-0.70.40.30.71.1-1.0-0.50.6-0.7-1.01.1-0.9
Condit. Reinf. lever presses0.10.10.60.1-0.3-0.20.8-0.10.10.1-0.50.50.60.40.3-0.3-0.10.60.30.0-0.4-0.80.4-0.20.1-0.1-0.4
Condit. Reinf. lever reinforcers received0.20.21.6-0.5-0.8-0.51.30.2-0.5-0.5-0.10.1-0.10.30.3-0.30.10.10.30.4-0.8-0.20.2-0.3-0.40.4-0.5
Conditioned reinforcement - actives0.31.03.11.61.61.6-0.6-1.51.81.8-0.30.3-0.0-0.1-0.50.2-1.1-0.3-0.2-1.60.50.4-0.40.30.7-0.71.2
Conditioned reinforcement - inactives0.82.26.22.52.42.4-0.7-2.42.32.3-0.70.7-0.00.5-1.6-0.3-2.0-0.10.3-2.01.70.1-0.1-0.10.4-0.41.5
Conditioned locomotion0.81.13.11.61.21.2-1.7-1.31.21.2-1.61.60.70.9-0.9-0.9-1.20.71.0-0.90.9-0.10.7-0.9-0.20.20.6
Patch foraging indifference point 0 sec0.10.20.60.30.00.3-0.6-0.00.10.1-0.70.70.80.5-0.1-0.5-0.10.70.50.10.2-0.60.6-0.4-0.00.2-0.6
Patch foraging indifference point AUC0.10.31.4-0.2-0.3-0.31.1-0.3-0.2-0.20.2-0.2-1.20.1-0.5-0.1-0.8-0.80.10.00.40.8-0.2-0.2-0.60.80.5
Delay disc. indifference point, 0s delay4.95.514.52.13.23.10.4-1.73.23.21.3-1.3-0.3-2.61.02.80.2-1.4-2.7-2.90.51.4-2.53.03.8-3.62.1
Delay disc. indifference point, 16s delay2.23.28.21.92.62.6-0.5-2.62.72.70.9-0.9-1.3-1.0-1.41.0-1.9-1.5-1.0-2.91.21.5-1.31.00.8-0.92.8
Delay disc. indifference point, 2s delay2.83.110.02.43.23.1-0.7-1.82.62.60.7-0.70.1-1.2-0.51.4-0.6-0.6-1.5-2.31.20.5-1.31.72.3-2.51.3
Delay disc. indifference point, 24s delay2.33.67.71.82.72.80.2-1.82.52.51.0-1.0-1.2-1.9-0.01.9-0.7-1.7-1.8-2.61.01.9-2.01.82.1-2.52.6
Delay disc. indifference point, 4s delay2.32.47.72.52.82.8-0.9-2.32.52.5-0.20.2-0.0-0.4-1.20.5-1.5-0.4-0.4-2.31.80.5-0.60.61.2-1.11.5
Delay disc. indifference point, 8s delay0.81.44.02.01.71.7-0.3-1.81.81.8-1.31.30.50.5-0.9-0.4-1.20.50.6-1.52.0-0.20.3-0.40.4-0.50.6
Indifference point function ln k0.10.21.7-0.1-0.10.0-1.3-0.20.10.1-0.10.10.00.3-0.5-0.4-0.30.00.4-0.10.30.10.3-0.5-0.70.60.2
Indifference point function log k0.10.21.7-0.1-0.10.0-1.3-0.20.10.1-0.10.10.00.3-0.5-0.4-0.30.00.4-0.10.30.10.3-0.5-0.70.60.2
Patch foraging total patch changes 0 sec0.10.40.80.50.10.4-0.6-0.20.20.2-0.90.90.80.8-0.4-0.7-0.30.90.70.10.4-0.80.8-0.6-0.20.4-0.6
Patch foraging total patch changes 12 sec0.20.20.90.50.20.1-0.5-0.10.30.3-0.70.71.00.40.1-0.30.00.80.3-0.0-0.6-0.80.5-0.10.4-0.2-0.4
Patch foraging total patch changes 18 sec0.10.21.40.70.30.40.3-0.50.30.3-0.70.70.00.6-0.6-0.5-0.70.20.5-0.11.2-0.30.3-0.5-0.20.3-0.0
Patch foraging total patch changes 24 sec0.51.75.3-1.3-1.7-1.42.32.0-1.5-1.50.0-0.00.8-0.42.20.42.00.7-0.41.7-1.7-0.7-0.00.50.8-0.6-1.8
Patch foraging total patch changes 6 sec0.40.82.00.80.30.5-0.6-0.90.50.5-1.41.40.31.2-0.9-1.2-1.20.61.3-0.30.4-0.50.9-1.2-0.80.90.2
Patch foraging time to switch 0 sec0.62.18.3-0.8-0.7-1.10.32.0-0.8-0.8-0.10.12.1-0.82.71.02.91.3-0.91.2-1.6-1.5-0.11.22.1-2.0-1.8
Patch foraging water rate 0 sec1.24.611.82.10.91.4-1.9-2.31.01.0-2.22.20.52.9-3.4-2.9-3.11.22.8-0.72.4-1.22.2-2.8-2.62.40.3
Patch foraging water rate 12 sec0.41.63.81.00.20.5-0.8-1.00.30.3-1.51.50.71.9-1.8-1.9-1.41.21.7-0.21.1-1.41.6-1.7-1.41.5-0.3
Patch foraging water rate 18 sec1.22.85.8-0.2-1.1-0.8-2.00.7-1.1-1.1-1.91.92.22.2-0.6-2.10.22.42.01.5-0.1-2.42.4-1.9-1.51.4-2.1
Patch foraging water rate 24 sec3.85.413.71.1-0.3-0.1-1.8-0.6-0.4-0.4-3.03.02.13.7-2.2-3.6-1.52.83.40.80.9-2.93.3-3.3-2.82.3-1.7
Patch foraging water rate 6 sec3.04.49.81.3-0.00.4-2.0-0.8-0.1-0.1-3.03.02.13.1-2.1-3.0-1.42.63.00.51.4-2.53.0-2.8-2.12.0-1.3
Seeking ratio, delayed vs. immediate footshock0.81.13.8-0.2-0.1-0.0-0.3-1.10.20.2-0.30.3-1.90.4-1.6-0.7-1.8-1.20.8-0.50.51.70.1-1.2-1.82.01.5
Distance traveled before self-admin0.30.72.7-0.8-0.2-0.30.70.4-0.3-0.31.0-1.0-1.6-1.10.41.0-0.0-1.5-0.90.1-0.61.7-1.10.70.3-0.11.1
Distance traveled after self-admin0.50.92.2-0.30.50.40.70.20.20.21.3-1.3-1.1-1.20.81.20.2-1.3-1.2-0.3-0.41.3-1.51.10.8-1.11.1
Extensor digitorum longus weight1.87.418.74.33.33.2-3.7-3.33.03.0-3.33.32.42.5-3.0-2.3-2.92.22.3-2.33.1-1.82.1-1.9-0.30.30.7
Bone: elastic displacement0.60.82.1-0.3-0.9-1.0-0.90.8-0.8-0.8-0.80.81.50.70.3-0.70.71.40.71.0-0.2-1.21.1-0.6-0.40.4-1.4
Bone: elastic work2.12.87.90.6-0.4-0.5-2.40.5-0.5-0.5-2.22.22.82.0-0.6-1.80.42.71.81.10.9-2.62.4-1.6-0.80.9-2.0
Bone: endosteal estimation0.40.92.10.3-0.4-0.3-0.9-0.1-0.2-0.2-1.41.40.81.4-0.7-1.4-0.41.01.40.50.7-1.01.2-1.3-1.01.1-0.6
Bone: endosteal perimeter0.51.33.01.40.80.9-1.3-1.40.90.9-1.41.40.61.4-1.6-1.3-1.40.81.3-0.71.7-0.81.1-1.2-0.80.70.3
Epididymis fat weight0.31.54.42.01.51.3-1.5-1.42.12.1-1.31.31.60.10.00.1-0.41.00.1-1.60.4-0.60.20.31.5-1.40.7
Delta time in closed arm before/after self-admin2.11.97.3-2.0-1.3-1.31.41.8-1.1-1.11.4-1.4-0.6-1.42.11.31.9-0.9-1.30.8-2.70.9-1.21.20.7-1.0-0.2
Delta time in open arm before/after self-admin1.82.16.12.52.22.2-0.7-2.32.32.3-1.21.20.60.6-1.3-0.5-1.70.50.6-2.02.0-0.50.4-0.40.4-0.30.9
Diff in mean of infusions in LGA sessions1.11.94.1-0.70.00.11.80.50.20.21.8-1.8-1.3-2.01.32.01.1-1.5-2.0-0.5-0.71.6-1.91.91.5-1.41.0
Delay discount exponential model param3.14.212.8-3.1-3.6-3.60.72.9-3.4-3.40.1-0.10.10.81.1-0.91.60.60.93.1-2.1-0.71.0-1.1-1.92.0-2.1
Extinction: sum of active levers before priming1.21.84.40.81.61.50.7-1.21.61.60.9-0.9-1.6-1.4-0.01.3-0.8-1.7-1.1-1.80.52.0-1.61.10.9-1.32.1
Active lever presses in extinction session 61.61.63.30.21.01.10.1-0.51.21.21.3-1.3-1.1-1.80.51.8-0.0-1.5-1.7-1.30.41.7-1.61.71.7-1.11.7
Bone: final force1.11.76.31.10.20.2-1.00.00.20.2-2.12.12.51.6-0.0-1.40.52.31.40.40.4-2.41.7-1.00.1-0.2-1.4
Bone: final moment1.21.95.61.10.10.2-1.5-0.20.20.2-2.22.22.41.8-0.4-1.60.12.31.60.30.4-2.31.8-1.3-0.30.2-1.3
Food consumed during 24 hour testing period0.81.54.40.7-0.00.0-0.5-1.10.20.2-1.31.3-0.11.8-1.9-1.9-1.70.61.8-0.11.0-0.71.4-1.8-1.92.10.1
Glucose6.19.728.84.03.83.7-0.3-4.93.53.5-1.01.0-2.81.3-4.8-1.4-5.4-1.81.5-3.85.21.9-0.2-1.6-1.82.14.0
Heart weight0.40.61.61.31.01.0-0.7-1.20.90.9-1.11.10.30.7-0.8-0.6-0.90.40.7-0.71.0-0.20.5-0.6-0.20.30.4
Delay discount hyperbolic model param3.34.313.2-3.1-3.6-3.60.82.8-3.4-3.40.1-0.10.00.81.1-1.01.50.60.93.1-2.2-0.61.0-1.1-1.92.1-2.0
Intermittent access intake day 1-15 change0.10.82.10.61.11.10.2-1.11.31.31.1-1.1-1.0-0.4-0.80.5-1.0-1.0-0.6-1.50.20.6-0.80.60.2-0.21.2
Intermittent access intake escalation0.21.02.80.91.41.4-0.2-1.41.51.50.9-0.9-1.1-0.3-1.10.3-1.4-1.1-0.5-1.70.40.8-0.70.50.1-0.11.4
Intermittent access intake escalation 20.20.31.00.40.40.4-0.8-0.60.50.50.1-0.10.00.6-1.0-0.5-0.80.10.4-0.60.4-0.50.4-0.4-0.60.60.1
Intermitt. access day 1 inactive lever presses0.00.51.31.01.11.0-0.3-1.11.01.00.2-0.2-0.4-0.0-0.80.0-1.0-0.4-0.1-1.00.50.4-0.30.10.1-0.10.8
Intermitt. access day 15 inactive lever presses0.41.95.32.21.81.8-0.1-2.31.61.6-0.80.80.11.2-2.2-1.1-2.10.41.0-1.42.3-0.60.7-0.9-0.70.70.7
Intermitt. access escalation Index0.20.51.9-0.8-0.7-0.71.40.8-0.6-0.61.1-1.1-0.2-0.60.60.61.0-0.2-0.80.4-0.2-0.3-0.40.70.4-0.4-0.7
Intermittent access day 1 total infusions0.31.02.61.11.51.5-0.2-1.01.41.40.2-0.2-0.1-1.00.31.1-0.3-0.5-1.0-1.20.40.8-1.01.11.6-1.61.0
Intermittent access day 15 total infusions0.81.95.11.92.32.2-0.7-2.02.22.20.2-0.2-0.6-0.3-1.00.4-1.6-0.8-0.5-2.10.90.8-0.80.60.8-0.81.8
Intermittent access terminal intake (last 3 days)0.61.12.81.51.71.6-0.9-1.71.71.7-0.00.0-0.40.1-1.1-0.0-1.5-0.4-0.0-1.60.70.4-0.30.10.2-0.21.3
Intermittent access total infusions1.11.33.31.51.81.8-1.0-1.81.81.8-0.00.0-0.6-0.0-1.20.1-1.7-0.7-0.1-1.81.00.8-0.50.10.2-0.21.6
Intermittent access day 1 locomotion0.10.20.9-0.5-0.3-0.30.40.2-0.4-0.40.1-0.1-0.5-0.50.60.40.2-0.5-0.20.3-0.81.0-0.50.20.2-0.20.3
Intermittent access day 15 total locomotion0.41.75.22.32.12.1-1.2-2.02.22.2-0.80.80.80.2-0.8-0.0-1.20.50.1-1.80.9-0.20.10.21.0-1.00.9
Intermittent access total locomotion1.01.33.71.61.61.6-0.9-1.91.71.7-0.40.4-0.50.3-1.3-0.3-1.8-0.50.3-1.61.00.7-0.2-0.3-0.10.11.5
Intermittent access standard deviation0.00.10.20.50.30.3-0.1-0.30.30.3-0.30.30.30.3-0.2-0.3-0.30.30.2-0.20.0-0.40.2-0.10.0-0.00.0
Left kidney weight0.64.615.71.90.20.1-3.0-0.50.70.7-3.53.54.02.6-0.4-2.3-0.13.62.40.30.3-3.22.8-1.9-0.10.3-1.8
Right kidney weight0.42.814.21.50.50.4-2.6-0.10.80.8-2.62.63.81.20.7-0.90.73.01.00.1-0.6-2.51.8-0.51.3-1.0-1.4
Cocaine induced anxiety0.61.65.21.51.61.6-0.9-2.21.61.60.2-0.2-0.80.5-2.3-0.5-2.2-0.50.4-1.91.60.20.1-0.4-0.80.81.4
Post-drug Anxiety1.51.74.31.51.91.9-0.1-1.72.02.00.8-0.8-0.8-0.8-0.90.8-1.3-1.0-0.9-2.11.00.9-1.00.90.8-0.81.7
Baseline Anxiety1.01.75.3-0.30.30.31.20.80.40.40.8-0.8-0.1-1.92.21.91.6-0.8-1.7-0.1-1.11.1-1.61.82.3-2.30.5
Tail length0.84.313.02.41.11.2-3.6-1.71.11.1-2.82.81.92.4-2.6-2.3-2.02.02.4-0.62.7-1.82.3-2.2-1.31.4-0.2
Length with tail1.66.919.33.31.81.8-4.4-2.31.91.9-3.83.82.93.0-2.8-2.8-2.22.92.9-1.03.0-2.42.9-2.6-1.01.2-0.3
Length without tail0.41.95.82.11.61.6-2.4-1.61.81.8-1.81.81.51.1-1.1-0.9-1.31.21.0-1.21.2-0.81.0-0.70.3-0.20.4
Times rat made contact with spout0.60.72.9-0.3-0.5-0.20.9-0.6-0.1-0.1-0.40.4-1.50.6-1.1-0.8-1.3-0.80.9-0.00.50.90.2-1.1-1.61.70.8
Lifetime Intake1.11.33.31.51.71.7-1.2-1.81.61.6-0.20.2-0.70.1-1.3-0.1-1.8-0.70.1-1.71.20.9-0.3-0.1-0.00.01.6
Liver weight, left0.20.30.90.0-0.3-0.4-0.60.2-0.1-0.1-0.90.90.90.50.4-0.50.10.80.50.4-0.4-0.60.6-0.40.0-0.0-0.5
Liver weight, right0.81.55.4-0.0-0.9-0.8-0.20.8-0.5-0.5-1.81.82.31.01.1-0.91.12.11.01.1-1.1-1.91.4-0.80.2-0.3-1.6
Locomotor activity1.21.84.50.80.30.3-0.8-1.10.10.1-1.61.6-0.41.8-2.0-1.9-2.00.32.0-0.01.6-0.11.2-2.1-2.11.90.3
Locomotor testing distance0.51.32.71.51.01.1-1.5-1.31.11.1-1.71.70.81.3-1.2-1.2-1.30.91.3-0.81.1-0.71.0-1.1-0.50.40.3
Locomotor testing rearing0.62.35.12.11.71.4-1.7-2.11.61.6-1.71.70.11.5-2.3-1.5-2.20.41.6-1.31.8-0.10.9-1.5-1.10.71.0
Locomotion in novel chamber0.30.41.6-0.6-0.5-0.50.40.6-0.2-0.20.6-0.6-0.1-0.61.00.60.9-0.3-0.70.1-1.30.1-0.60.70.7-0.60.0
Locomotion in novel chamber post-restriction0.61.77.1-1.5-1.1-1.12.71.2-0.9-0.91.5-1.5-1.5-1.31.51.31.2-1.4-1.30.5-1.51.2-1.41.10.6-0.50.1
Fecal boli incidents, locomotor time 10.10.31.3-0.5-0.5-0.50.20.0-0.6-0.6-0.20.2-0.80.5-0.2-0.5-0.6-0.40.50.3-0.50.30.1-0.6-0.91.10.4
Change in fecal boli incidents, locomotor task0.30.30.9-0.7-0.8-0.81.00.5-0.9-0.90.6-0.6-0.7-0.0-0.1-0.10.2-0.40.00.70.50.4-0.0-0.2-0.80.5-0.4
Time >=10cm from walls, locomotor time 11.21.55.2-0.6-0.4-0.41.11.00.20.20.8-0.80.6-1.42.31.62.1-0.0-1.50.1-1.5-0.2-1.11.72.2-1.9-0.2
Bouts of movement, locomotor time 10.60.71.6-0.00.40.41.10.30.30.31.0-1.0-0.5-1.20.81.20.7-0.7-1.2-0.31.20.6-1.11.21.2-0.90.1
Total resting periods, locomotor time 10.70.81.80.20.50.61.30.20.30.31.0-1.0-0.5-1.20.71.20.7-0.8-1.2-0.41.10.6-1.21.31.2-1.10.2
Rest time, locomotor task time 10.20.30.70.3-0.1-0.10.40.1-0.5-0.5-0.80.80.20.7-0.2-0.7-0.30.40.70.60.9-0.30.5-0.7-0.60.5-0.4
Distance moved, locomotor task time 10.00.10.9-0.3-0.3-0.4-0.70.10.00.0-0.10.10.60.10.1-0.10.40.50.1-0.0-0.9-0.40.4-0.1-0.10.1-0.3
Vertical activity count, locomotor time 10.10.61.6-1.3-0.7-0.80.30.6-0.5-0.51.2-1.2-1.1-0.80.40.70.4-1.0-0.70.1-1.11.1-0.70.5-0.20.20.4
Time >=10cm from walls, locomotor time 20.10.20.9-0.6-0.3-0.40.70.4-0.2-0.20.0-0.0-0.2-0.50.90.40.5-0.2-0.30.3-0.70.5-0.40.30.4-0.30.2
Bouts of movement, locomotor time 20.10.31.00.90.91.00.2-0.71.01.0-0.30.30.3-0.00.00.1-0.40.1-0.1-0.70.4-0.2-0.20.30.8-0.50.3
Total resting periods, locomotor time 20.10.41.31.01.01.10.6-0.81.11.1-0.30.30.2-0.10.10.2-0.40.0-0.2-0.80.5-0.1-0.30.40.9-0.70.4
Rest time, locomotor task time 20.20.30.8-0.2-0.7-0.60.60.6-0.7-0.7-0.70.70.40.50.3-0.50.30.50.60.90.0-0.30.5-0.6-0.50.2-0.6
Distance moved, locomotor task time 20.10.21.0-0.6-0.3-0.5-0.20.5-0.3-0.30.4-0.40.3-0.30.50.40.80.1-0.40.3-1.0-0.2-0.10.40.3-0.0-0.4
Vertical activity count, locomotor time 20.30.71.9-0.70.20.10.10.10.10.11.3-1.3-1.3-1.10.31.00.0-1.4-1.0-0.5-0.31.3-1.10.90.4-0.11.0
Light reinforcement 10.31.64.61.50.60.7-1.4-0.30.70.7-2.02.02.21.6-0.5-1.5-0.22.01.5-0.10.4-1.81.5-1.2-0.2-0.1-0.9
Light reinforcement 21.02.26.70.7-0.3-0.2-1.30.4-0.3-0.3-2.42.42.62.0-0.0-1.80.22.51.81.0-0.1-2.32.0-1.6-0.60.2-1.7
Bone: marrow area0.30.61.50.2-0.4-0.3-0.7-0.1-0.2-0.2-1.21.20.61.2-0.5-1.2-0.30.81.20.40.6-0.81.0-1.1-0.90.9-0.5
Bone: maximum diameter2.85.513.03.62.52.5-2.5-2.92.52.5-2.92.92.02.5-2.8-2.3-2.62.12.3-1.82.7-1.92.2-2.0-0.80.70.4
Bone: maximum force1.02.06.50.9-0.1-0.1-1.30.1-0.0-0.0-2.22.22.51.8-0.2-1.60.32.41.60.60.4-2.41.9-1.3-0.30.2-1.5
Bone: maximum moment1.22.35.70.9-0.1-0.1-1.9-0.1-0.0-0.0-2.32.32.42.1-0.7-1.9-0.12.41.90.50.4-2.42.2-1.7-0.80.6-1.4
Mean time between licks in bursts0.10.93.8-0.7-0.8-0.80.10.3-1.1-1.1-0.20.2-1.10.8-1.2-1.0-0.6-0.51.00.70.90.50.5-1.3-2.01.8-0.1
Mean num. licks in bursts0.41.27.3-1.0-0.7-0.42.7-0.0-0.4-0.41.3-1.3-2.2-0.90.20.7-0.4-1.7-0.7-0.1-0.61.6-1.10.4-0.40.60.8
Cd content in liver0.10.11.30.30.30.2-0.2-0.1-0.1-0.1-0.10.1-0.20.3-0.7-0.3-0.2-0.00.3-0.01.1-0.00.2-0.3-0.50.4-0.1
Co content in liver0.50.61.71.11.21.3-0.5-1.31.31.3-0.10.1-0.10.1-0.7-0.0-0.9-0.2-0.0-1.20.5-0.1-0.10.10.3-0.40.9
Cu content in liver0.80.92.0-0.20.50.50.6-0.10.40.41.3-1.3-1.2-1.40.41.30.1-1.4-1.3-0.70.01.3-1.41.20.9-0.81.1
Fe content in liver2.12.67.1-1.4-0.5-0.52.70.6-0.3-0.32.5-2.5-2.2-2.01.51.90.8-2.3-2.0-0.2-1.41.7-2.31.91.0-0.81.0
K content in liver2.32.24.91.42.12.2-1.0-1.42.02.01.0-1.0-0.7-1.4-0.21.5-1.0-1.3-1.4-2.00.51.4-1.51.51.7-1.81.9
Mg content in liver1.51.74.92.12.22.2-1.4-1.82.12.1-0.20.20.3-0.3-0.80.4-1.3-0.1-0.4-1.90.70.3-0.40.61.1-1.21.4
Mn content in liver0.20.20.90.10.40.2-0.4-0.60.50.50.3-0.3-0.8-0.3-0.50.2-0.8-0.7-0.1-0.70.30.9-0.30.0-0.30.20.9
Na content in liver4.04.510.52.02.82.80.4-2.62.82.81.3-1.3-2.2-1.6-1.11.6-1.8-2.4-1.5-3.11.22.4-2.11.51.3-1.53.2
Rb content in liver0.20.30.90.80.90.9-0.3-0.60.80.80.1-0.10.1-0.2-0.00.3-0.3-0.1-0.3-0.7-0.0-0.1-0.30.40.7-0.90.4
Se content in liver1.21.53.81.52.01.8-1.8-1.71.71.70.2-0.2-0.5-0.3-1.30.3-1.6-0.7-0.2-1.71.70.9-0.40.20.2-0.11.6
Sr content in liver2.11.83.82.01.21.2-1.3-1.61.21.2-1.71.70.91.4-1.8-1.4-1.51.01.4-1.01.8-0.81.3-1.3-0.80.80.4
Zn content in liver0.91.13.10.7-0.0-0.0-1.8-0.60.10.1-1.31.31.11.4-1.2-1.4-0.71.21.40.00.7-1.01.5-1.4-1.11.1-0.6
Bone: minimum diameter0.61.12.50.4-0.4-0.3-1.1-0.1-0.1-0.1-1.61.61.41.5-0.6-1.4-0.21.51.40.40.4-1.41.5-1.3-0.80.8-0.9
Time in familiar zone, hab. session 11.01.12.8-1.5-1.7-1.71.11.6-1.6-1.60.5-0.50.2-0.11.30.21.50.2-0.21.4-1.1-0.6-0.00.2-0.00.0-1.3
Time in novel zone, hab. session 11.01.13.31.21.21.2-1.8-1.41.11.1-0.90.90.30.8-1.5-0.8-1.60.40.9-0.91.10.10.7-0.9-0.70.70.7
Total zone transitions, hab. session 10.20.32.2-0.7-0.9-0.71.50.6-0.8-0.80.2-0.2-0.6-0.10.50.10.4-0.3-0.00.7-0.60.5-0.2-0.1-0.30.2-0.3
Total locomotion distance, hab. session 10.20.41.8-0.3-0.1-0.00.8-0.2-0.1-0.10.7-0.7-1.4-0.5-0.30.4-0.4-1.1-0.4-0.20.01.3-0.70.2-0.30.20.7
Locomotion velocity, hab. session 10.20.31.4-0.2-0.1-0.11.2-0.0-0.1-0.10.7-0.7-1.2-0.6-0.00.5-0.1-1.0-0.5-0.1-0.01.1-0.80.4-0.0-0.10.5
Time in familiar zone, hab. session 22.62.96.9-2.6-1.9-2.01.72.6-2.1-2.11.8-1.8-0.4-1.42.31.42.3-0.6-1.51.9-2.00.3-0.91.30.7-0.6-1.2
Time in novel zone, hab. session 23.74.07.72.61.51.7-2.1-2.31.71.7-2.82.81.62.5-2.4-2.4-2.21.82.4-1.31.8-1.62.1-2.2-1.21.10.2
Total zone transitions, hab. session 20.10.20.70.60.20.20.4-0.30.10.1-0.60.60.10.5-0.6-0.5-0.40.30.50.00.8-0.20.4-0.5-0.40.1-0.1
Total locomotion distance, hab. session 20.40.51.60.90.40.3-0.1-0.80.30.3-0.70.70.00.9-1.3-0.9-0.90.40.9-0.31.2-0.40.7-0.9-0.80.60.1
Locomotion velocity, hab. session 20.30.51.91.00.70.6-0.1-0.90.50.5-0.50.5-0.20.6-1.3-0.6-1.00.10.6-0.61.4-0.10.4-0.6-0.50.30.4
Novel to familiar place preference ratio1.41.83.81.41.71.80.9-1.81.91.90.8-0.8-1.4-0.9-0.90.9-1.2-1.4-0.9-2.01.11.5-1.20.80.7-0.71.9
Novelty place preference1.21.53.51.51.71.80.6-1.91.81.80.5-0.5-1.2-0.6-1.10.5-1.4-1.1-0.5-1.81.31.3-0.80.50.4-0.41.7
Time in novel zone, NPP test1.01.33.21.41.61.70.5-1.81.71.70.2-0.2-1.0-0.3-1.20.3-1.4-0.9-0.3-1.71.31.0-0.60.20.2-0.21.5
Total zone transitions, NPP test0.10.20.9-0.10.00.20.40.20.00.00.4-0.4-0.0-0.50.50.60.4-0.2-0.5-0.0-0.90.3-0.40.60.6-0.90.1
Total locomotion distance, NPP test0.40.61.00.00.40.50.6-0.40.60.61.0-1.0-0.8-0.90.20.9-0.1-0.9-1.0-0.8-0.80.9-1.00.90.7-0.90.9
Locomotion velocity, NPP test0.81.11.90.10.60.70.7-0.50.70.71.4-1.4-1.1-1.40.31.4-0.2-1.3-1.4-1.0-0.71.3-1.41.31.0-1.21.2
Intraocular pressure0.20.31.40.5-0.4-0.31.2-0.20.10.1-0.80.80.60.6-0.1-0.60.10.70.60.20.8-0.80.6-0.5-0.10.3-0.6
Delta distance traveled before/after self-admin0.30.31.80.40.60.60.3-0.00.60.60.4-0.40.4-0.60.80.60.6-0.1-0.6-0.50.10.0-0.60.70.9-1.30.2
Delta ambulatory time before/after self-admin0.20.41.1-0.40.10.10.50.4-0.0-0.00.9-0.9-0.3-0.70.90.70.7-0.6-0.7-0.1-0.60.6-0.90.70.4-1.00.3
Parametrial fat weight0.81.96.41.51.61.62.5-1.91.61.60.7-0.7-1.7-0.7-0.80.7-1.1-1.5-0.7-1.91.41.2-1.20.70.5-0.71.7
Pavlov. Cond. lever latency0.20.20.9-0.20.30.2-0.4-0.1-0.1-0.10.6-0.6-0.90.1-0.6-0.1-0.6-0.80.0-0.10.30.6-0.3-0.1-0.60.70.5
Pavlov. Cond. magazine entry latency0.40.61.6-1.2-1.1-1.31.11.0-1.2-1.20.3-0.3-0.2-0.20.60.10.80.0-0.01.0-0.40.20.2-0.1-0.60.5-0.8
Pavlov. Cond. change in total contacts0.50.61.10.90.90.80.7-1.01.01.00.2-0.2-0.6-0.7-0.30.7-0.6-0.6-0.6-1.10.81.0-0.60.50.6-0.61.0
Pavlov. Cond. index score0.40.51.6-0.9-0.9-0.91.30.8-0.7-0.70.4-0.4-0.1-0.81.10.71.0-0.1-0.60.6-0.70.4-0.30.50.4-0.5-0.5
Pavlov. Cond. latency score0.30.41.2-0.8-0.9-1.01.10.8-0.7-0.70.2-0.20.3-0.61.10.51.10.2-0.40.7-0.70.0-0.10.40.4-0.5-0.7
Pavlov. Cond. lever contacts0.20.20.8-0.2-0.6-0.50.70.4-0.2-0.2-0.30.30.7-0.30.90.30.80.5-0.20.4-0.6-0.30.10.30.6-0.8-0.6
Pavlov. Cond. magazine entry number0.40.63.21.00.70.9-1.8-0.60.70.7-0.80.81.00.8-0.6-0.7-0.60.70.6-0.40.6-1.00.6-0.40.1-0.00.0
Pavlov. Cond. intertrial magazine entries0.30.41.90.90.80.9-1.4-0.81.11.1-0.50.50.60.2-0.3-0.1-0.50.30.1-0.8-0.2-0.20.10.00.5-0.50.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-0.9-0.9-1.01.10.8-0.7-0.70.3-0.30.1-0.71.10.61.10.1-0.50.7-0.80.3-0.20.40.4-0.5-0.6
Pavlov. Cond. response bias0.10.20.7-0.3-0.2-0.30.80.00.00.00.4-0.4-0.5-0.70.40.60.2-0.5-0.5-0.1-0.30.8-0.50.40.3-0.40.3
Pavlov. Cond. lever latency0.40.54.81.11.20.9-2.2-0.40.60.6-0.40.40.70.1-0.6-0.0-0.10.40.0-0.50.9-0.20.10.10.4-0.50.2
Pavlov. Cond. magazine entry latency0.10.10.50.50.30.40.3-0.10.20.2-0.60.60.70.30.2-0.20.10.60.20.0-0.2-0.60.3-0.10.3-0.4-0.2
Pavlov. Cond. change in total contacts0.10.22.3-0.4-0.6-0.31.50.2-0.2-0.20.0-0.00.00.10.6-0.00.20.1-0.00.2-0.9-0.3-0.00.10.1-0.1-0.3
Pavlov. Cond. index score0.10.22.0-0.5-0.6-0.41.40.3-0.3-0.30.0-0.00.00.10.5-0.10.20.20.00.4-0.6-0.30.1-0.0-0.10.0-0.4
Pavlov. Cond. latency score0.10.21.9-0.6-0.7-0.41.40.4-0.4-0.40.0-0.00.00.10.6-0.10.30.20.00.5-0.7-0.30.1-0.1-0.10.0-0.5
Pavlov. Cond. lever contacts0.50.75.5-1.3-1.2-0.92.30.5-0.6-0.60.8-0.8-1.0-0.50.80.40.2-0.7-0.40.4-1.10.5-0.50.3-0.20.2-0.0
Pavlov. Cond. magazine entry number0.40.51.3-0.30.10.1-0.0-0.20.30.31.1-1.1-1.1-0.9-0.00.9-0.1-1.2-0.9-0.60.01.1-1.00.80.3-0.30.8
Pavlov. Cond. intertrial magazine entries0.10.30.9-0.1-0.0-0.1-0.1-0.60.40.40.5-0.5-1.0-0.4-0.40.3-0.6-0.9-0.3-0.60.10.8-0.50.2-0.10.30.9
Pavlov. Cond. lever-magazine prob. diff.0.20.21.9-0.6-0.8-0.61.40.5-0.5-0.5-0.10.10.10.10.7-0.10.40.30.10.5-0.8-0.30.2-0.1-0.10.0-0.5
Pavlov. Cond. response bias0.20.32.9-0.7-0.8-0.61.70.3-0.3-0.30.2-0.2-0.4-0.20.70.20.1-0.2-0.20.3-0.90.1-0.20.1-0.00.1-0.1
Time in closed arm before self-admin0.91.64.0-0.5-1.1-1.1-1.40.7-1.2-1.2-1.01.01.61.5-0.3-1.50.41.71.41.3-0.1-2.01.6-1.3-1.31.1-1.9
Time in closed arm after self-admin1.01.24.1-1.6-1.7-1.7-0.31.5-1.5-1.50.3-0.30.70.21.0-0.21.40.60.11.3-2.0-0.90.5-0.2-0.50.2-1.3
Time in open arm before self-admin0.00.00.20.00.00.0-0.10.3-0.1-0.1-0.30.3-0.0-0.20.00.20.20.0-0.10.20.20.40.00.10.4-0.20.0
Time in open arm after self-admin0.70.82.71.51.31.40.3-1.21.31.3-1.01.00.30.3-0.5-0.3-0.80.30.3-1.01.6-0.00.2-0.20.4-0.40.5
Bone: periosteal estimation1.02.35.61.80.80.9-1.9-1.10.90.9-2.42.42.11.9-1.2-1.8-0.82.11.8-0.41.3-1.91.9-1.5-0.50.5-0.6
Bone: periosteal perimeter1.42.77.72.82.02.0-1.8-2.12.12.1-1.91.91.71.3-1.7-1.2-1.51.51.2-1.51.8-1.41.2-0.90.2-0.40.4
Bone: post-yield work0.10.20.9-0.4-0.3-0.3-0.4-0.1-0.2-0.2-0.10.1-0.50.5-0.5-0.6-0.6-0.20.50.1-0.70.30.3-0.6-0.90.70.2
Progressive ratio test 1 active lever presses1.22.25.31.21.91.9-0.2-1.91.91.90.8-0.8-1.7-1.0-0.71.0-1.6-1.8-0.9-2.11.02.1-1.50.90.7-0.72.3
Progressive ratio test 1 breakpoint1.32.25.41.32.01.9-0.2-1.91.91.90.8-0.8-1.7-1.1-0.71.0-1.6-1.8-1.0-2.11.02.1-1.50.90.8-0.82.3
Progressive ratio test 1 inactive lever presses1.02.57.02.12.52.5-0.4-2.62.32.30.3-0.3-1.1-0.2-1.70.3-2.2-1.1-0.3-2.41.51.0-0.80.40.4-0.42.1
Progressive ratio test 2 active lever presses0.60.82.21.11.41.4-0.3-1.31.41.40.4-0.4-0.4-0.4-0.60.4-1.0-0.6-0.5-1.50.90.6-0.60.50.5-0.51.0
Progressive ratio test 2 breakpoint0.50.71.91.11.31.3-0.3-1.21.31.30.4-0.4-0.3-0.3-0.50.4-0.9-0.5-0.4-1.40.80.4-0.50.50.5-0.50.9
Progressive ratio test 2 inactive lever presses0.61.96.82.62.22.2-0.6-2.22.22.2-0.90.90.90.6-1.2-0.4-1.30.60.3-1.81.7-0.80.3-0.10.8-0.80.6
Incentive Sensitization - Responses0.10.20.80.70.60.5-0.1-0.30.60.6-0.10.10.90.10.10.00.20.6-0.1-0.50.4-0.90.20.30.7-0.7-0.4
Incentive Sensitization - Breakpoint0.10.31.20.70.40.4-0.2-0.20.50.5-0.30.31.10.30.1-0.10.20.80.0-0.40.4-1.10.40.20.6-0.6-0.6
Sum of active levers in priming session hrs 5-61.51.42.70.51.21.2-0.0-0.81.31.31.0-1.0-0.7-1.60.31.6-0.1-1.1-1.5-1.3-0.21.6-1.31.41.4-1.61.3
Progressive ratio0.00.10.50.1-0.2-0.0-0.3-0.20.30.3-0.70.70.40.30.1-0.30.10.40.4-0.1-0.0-0.30.3-0.30.00.20.2
Food seeking constrained by brief footshock1.01.33.51.91.71.7-1.4-1.61.81.8-1.11.10.80.2-0.6-0.2-0.90.40.4-1.41.40.20.2-0.30.4-0.81.0
Seeking ratio, punishment vs. effort0.20.51.71.21.11.1-0.8-1.00.90.9-0.20.20.30.3-1.0-0.3-1.00.20.2-0.81.3-0.10.2-0.2-0.2-0.10.2
Retroperitoneal fat weight0.20.94.41.51.11.12.1-0.81.31.3-0.10.10.2-0.50.40.60.20.0-0.6-1.11.0-0.3-0.70.81.5-1.50.4
Reaction time number correct1.03.49.30.0-1.1-1.0-1.1-0.3-0.8-0.8-2.22.20.72.8-1.8-2.9-1.21.52.90.80.5-1.52.3-3.0-3.12.5-0.9
Reaction time mean minus median0.00.31.1-0.30.10.10.1-0.20.10.11.0-1.0-1.0-0.6-0.30.6-0.6-0.9-0.6-0.30.00.9-0.60.50.10.20.7
Reaction time mean minus median AUC0.00.20.60.60.70.8-0.3-0.50.60.60.1-0.10.2-0.1-0.20.2-0.40.1-0.3-0.50.1-0.1-0.10.30.5-0.50.3
Reaction time num false alarms0.71.24.31.11.31.30.4-0.51.31.30.5-0.50.7-1.11.01.30.70.0-1.3-1.0-0.60.1-0.91.52.1-2.00.3
Reaction time num false alarms AUC0.51.04.51.01.01.10.2-0.11.11.10.2-0.21.3-0.91.31.11.10.6-1.1-0.7-0.7-0.4-0.51.42.1-1.9-0.2
Reaction time trials correct on left1.03.49.30.0-1.1-1.0-1.1-0.3-0.8-0.8-2.22.20.72.8-1.8-2.9-1.21.52.90.80.5-1.52.3-3.0-3.12.5-0.9
Reaction time trials on left1.03.39.3-0.0-1.1-1.0-1.0-0.3-0.8-0.8-2.22.20.72.8-1.7-2.9-1.21.42.90.80.5-1.42.3-3.0-3.02.5-0.9
Reaction time mean0.40.92.8-0.8-0.0-0.10.30.5-0.1-0.11.7-1.7-0.9-1.40.71.40.4-1.1-1.4-0.2-0.61.0-1.21.30.8-0.70.6
Reaction time mean AUC0.30.72.4-0.8-0.1-0.20.20.5-0.2-0.21.6-1.6-0.7-1.20.71.20.4-1.0-1.3-0.1-0.70.8-1.11.20.7-0.70.4
Median of all reaction times0.71.02.9-1.0-0.2-0.30.40.7-0.2-0.21.7-1.7-0.8-1.51.01.50.8-1.1-1.5-0.1-0.70.9-1.31.41.0-0.90.4
Reaction time omissions0.10.20.6-0.4-0.4-0.40.80.1-0.1-0.10.6-0.6-0.6-0.40.20.40.0-0.5-0.50.0-0.60.3-0.50.40.1-0.20.2
Reaction time false alarm rate2.02.711.61.01.51.50.4-0.11.51.51.1-1.11.0-2.11.92.31.5-0.1-2.3-1.1-0.80.2-1.52.63.4-2.90.3
Reaction time premature initiation rate1.21.95.4-1.6-1.8-1.81.42.3-1.9-1.90.0-0.00.9-0.32.00.32.20.7-0.32.1-1.5-0.70.20.40.6-0.5-1.9
Reaction time premature initiations0.61.94.3-1.3-2.0-1.90.61.7-1.9-1.9-1.01.01.01.20.7-1.21.21.31.22.1-0.9-1.31.3-1.2-1.00.9-2.0
Std. dev. reaction times0.10.41.3-0.40.10.00.40.2-0.0-0.01.2-1.2-0.6-0.90.30.90.1-0.7-1.0-0.1-0.50.5-0.71.00.7-0.40.3
Reaction time trials completed1.03.39.3-0.0-1.1-1.0-1.0-0.3-0.8-0.8-2.22.20.72.8-1.7-2.9-1.21.42.90.80.5-1.42.3-3.0-3.02.5-0.9
Reaction time trials AUC0.93.39.40.0-1.0-0.9-1.2-0.4-0.7-0.7-2.12.10.62.8-1.9-2.9-1.31.42.80.70.5-1.32.3-3.0-3.12.5-0.8
Run reversals in cocaine runway, females2.83.16.6-1.2-0.3-0.32.11.2-0.3-0.32.0-2.0-0.7-2.42.62.52.2-1.3-2.40.1-2.11.3-2.12.42.3-2.30.3
Run reversals in cocaine runway, males0.10.10.40.3-0.0-0.0-0.4-0.20.00.0-0.40.40.40.3-0.5-0.4-0.20.50.4-0.10.6-0.00.5-0.5-0.60.4-0.3
Latency to leave start box in cocaine runway0.20.31.00.40.80.70.6-0.20.50.5-0.20.2-0.4-0.60.50.60.1-0.6-0.4-0.30.11.0-0.70.40.7-0.80.6
Latency to leave start box in cocaine runway, F0.40.61.61.20.90.9-0.3-0.30.70.7-1.21.21.30.10.2-0.00.41.00.2-0.20.8-0.60.40.00.9-0.9-0.3
Latency to leave start box in cocaine runway, M1.11.04.7-0.40.50.51.1-0.30.20.21.0-1.0-2.2-0.80.10.7-0.7-2.0-0.6-0.5-0.52.1-1.50.4-0.2-0.11.6
Std. dev. time between licks in bursts0.30.61.8-1.2-1.1-1.30.61.1-1.4-1.40.1-0.1-0.60.00.3-0.10.8-0.30.21.20.50.40.0-0.4-0.70.7-0.7
Total sessions with >9 infusions0.00.10.20.10.20.20.2-0.40.20.20.1-0.1-0.4-0.0-0.10.0-0.4-0.3-0.0-0.3-0.20.3-0.20.0-0.10.10.4
Short access day 1 total inactive lever presses1.12.24.62.21.61.6-1.5-2.11.61.6-1.71.70.41.5-2.0-1.4-2.10.61.5-1.32.0-0.41.0-1.4-0.80.81.0
Short access day 10 total inactive lever presses0.31.83.91.20.40.4-1.3-1.10.50.5-1.81.80.82.0-1.8-1.9-1.41.21.9-0.41.1-1.11.7-1.8-1.51.5-0.2
Short access day 1 total infusions0.00.00.10.20.10.2-0.2-0.20.20.2-0.30.30.10.00.20.0-0.00.00.0-0.1-0.20.2-0.10.00.2-0.20.2
Short access day 10 total infusions0.10.10.5-0.3-0.1-0.10.40.1-0.1-0.10.3-0.3-0.7-0.30.20.3-0.1-0.6-0.2-0.0-0.40.7-0.50.20.1-0.10.4
Short access total infusions0.10.20.60.40.50.5-0.4-0.70.50.5-0.20.2-0.40.1-0.5-0.2-0.8-0.40.2-0.60.40.5-0.1-0.2-0.20.20.7
Short access day 1 locomotion0.40.61.2-0.6-1.1-1.0-0.40.6-0.8-0.8-0.70.70.60.80.1-0.90.30.80.90.9-0.6-0.60.9-0.9-0.90.9-0.7
Short access day 10 total locomotion0.31.23.7-1.9-1.7-1.71.01.0-1.7-1.70.7-0.7-1.4-0.00.4-0.20.3-0.90.21.3-1.51.0-0.2-0.5-1.31.3-0.2
Short access total locomotion0.71.02.7-1.4-1.7-1.60.50.9-1.5-1.5-0.20.2-0.50.70.0-0.90.10.00.91.3-1.00.10.6-1.1-1.61.6-0.7
One hour access (0.3 mA shock)0.80.92.50.91.11.1-0.4-1.41.41.40.3-0.3-1.1-0.3-0.80.3-1.3-1.1-0.2-1.60.61.2-0.70.20.1-0.11.6
Compulsive drug intake1.42.05.0-2.1-1.5-1.51.51.9-1.4-1.41.1-1.1-0.9-1.52.21.41.8-1.1-1.21.1-2.11.4-1.31.10.7-0.7-0.1
One hour access (shock baseline)0.92.36.12.02.22.2-1.3-2.52.22.2-0.00.0-0.90.3-2.0-0.2-2.4-0.90.2-2.21.70.8-0.4-0.1-0.20.21.9
Social response proportion0.50.62.4-0.4-0.7-0.7-0.20.1-0.7-0.7-0.10.1-0.30.9-1.2-1.0-0.60.20.90.51.0-0.50.8-1.0-1.51.5-0.5
Social responses0.81.02.80.3-0.4-0.4-0.6-0.70.10.1-1.01.0-0.11.5-1.6-1.5-1.20.41.5-0.11.2-0.61.1-1.5-1.71.5-0.1
Social time0.40.72.6-1.6-1.5-1.60.50.9-1.1-1.11.2-1.2-0.8-0.30.10.20.4-0.5-0.30.6-0.50.1-0.20.1-0.70.7-0.4
Soleus weight2.36.815.62.30.70.7-4.0-1.40.60.6-3.93.93.23.6-2.4-3.4-1.73.43.4-0.11.4-3.03.5-3.1-1.81.8-1.4
Bone: stiffness0.20.31.30.30.30.30.7-0.00.40.4-0.20.20.7-0.20.90.40.60.4-0.4-0.2-0.7-0.5-0.20.51.1-1.2-0.1
Tibialis anterior weight1.03.48.62.92.32.3-2.3-2.32.02.0-2.32.31.51.7-2.0-1.5-2.01.51.6-1.61.8-1.21.5-1.3-0.20.20.5
Time to tail flick, vehicle, before self-admin0.50.61.8-0.4-0.2-0.20.40.5-0.1-0.11.2-1.20.8-0.71.00.81.20.3-1.0-0.1-1.0-0.9-0.41.11.0-1.3-0.7
Time to tail flick, vehicle, after self-admin0.81.63.3-0.70.20.21.80.5-0.1-0.11.6-1.6-1.6-1.61.11.60.7-1.7-1.6-0.3-1.71.5-1.81.51.1-1.61.2
Time to tail flick, test, before self-admin0.30.32.60.0-0.5-0.4-0.3-0.3-0.1-0.1-0.30.30.10.7-0.6-0.7-0.60.30.6-0.00.7-0.60.6-0.6-0.61.6-0.2
Time to tail flick, test, after self-admin3.13.37.81.91.11.1-2.2-2.41.41.4-1.91.91.02.3-2.8-2.2-2.51.42.1-1.31.1-1.42.0-2.1-1.71.80.1
Delta time to tail flick, vehicle, before/after SA0.80.84.5-0.40.10.21.40.1-0.1-0.10.3-0.3-1.9-0.90.40.7-0.2-1.7-0.5-0.1-0.72.1-1.30.40.2-0.41.5
Delta time to tail flick, test, before/after SA0.70.82.01.11.00.9-1.1-1.20.70.7-1.11.10.31.0-1.4-1.1-1.30.61.1-0.60.3-0.30.9-1.1-1.00.30.2
Tibia length0.41.14.3-0.3-0.7-0.8-1.01.1-0.6-0.6-0.80.82.10.31.2-0.21.51.60.21.0-1.3-1.50.8-0.00.7-0.7-1.6
Ambulatory time before self-admin0.41.23.5-0.60.10.00.70.20.20.21.3-1.3-1.7-1.50.61.40.0-1.8-1.4-0.4-0.61.9-1.51.30.9-0.61.5
Ambulatory time after self-admin1.11.84.3-1.00.20.11.10.5-0.1-0.11.9-1.9-1.9-1.81.21.70.5-2.1-1.7-0.3-1.22.1-2.01.50.9-1.21.4
Bone: tissue strength2.82.96.0-0.2-1.5-1.5-1.50.3-1.0-1.0-2.22.21.62.4-0.8-2.4-0.32.02.41.3-0.1-2.12.4-2.3-2.01.8-1.5
Total heroin consumption0.20.20.8-0.4-0.6-0.5-0.40.2-0.3-0.3-0.90.90.30.40.2-0.4-0.00.40.50.40.1-0.10.4-0.5-0.20.80.0
Bone: trabecular number0.10.30.8-0.9-0.7-0.6-0.60.8-0.7-0.70.5-0.5-0.5-0.60.40.50.4-0.5-0.40.60.10.7-0.40.3-0.1-0.10.1
Bone: trabecular spacing0.60.91.71.30.60.6-0.2-1.00.70.7-1.31.30.91.3-1.1-1.2-0.81.11.1-0.41.1-1.21.1-1.0-0.50.7-0.3
Bone: trabecular thickness0.71.03.4-1.8-1.4-1.4-0.41.6-1.3-1.30.8-0.8-0.3-0.91.30.81.2-0.5-0.71.1-1.20.8-0.50.50.1-0.1-0.5
Bone: trabecular tissue density0.30.51.3-0.6-0.2-0.21.1-0.00.20.20.8-0.8-0.8-0.90.80.90.4-0.9-0.9-0.5-1.01.0-0.90.80.7-0.40.7
Water consumed over 24 hours0.91.76.3-0.9-1.3-1.2-0.10.2-1.1-1.1-1.01.0-0.51.6-1.2-1.8-0.90.31.81.00.1-0.21.3-2.0-2.52.5-0.5
Number of responses in last shaping day1.11.43.3-0.20.40.41.80.10.40.41.3-1.3-0.8-1.61.41.60.7-1.2-1.6-0.5-1.21.1-1.61.71.7-1.70.6