Hub : Genes

Slc43a3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Slc43a3 0.49 0.02 1.3e-03 -0 0.04 0.01 -0 7.0e-01 1.1e-05 2.2e-02 9.6e-01
2 Liver isoform ratio XM_017591713.3 0.5 0.02 9.4e-03 0.01 0 0.01 0.01 4.3e-02 1.4e-01 8.4e-03 3.7e-02
3 Adipose isoform ratio XM_017591713.3 0.26 0.12 5.0e-09 0.07 0.06 0.06 0.06 4.4e-08 2.0e-07 1.6e-07 1.1e-07
4 Adipose intron excision ratio chr3_90422494_90426224 0.32 0.09 8.8e-10 0.07 0.07 0.07 0.07 2.0e-08 6.8e-08 6.1e-08 5.6e-08
5 PL isoform ratio XM_039104888.1 0.03 0.04 2.9e-03 0.02 0.02 0.02 0.02 3.2e-03 3.1e-03 4.3e-03 4.9e-03
6 Liver intron excision ratio chr3_90427694_90429546 0.07 0.06 3.9e-08 0.06 0.05 0.05 0.06 4.8e-07 1.6e-06 1.1e-06 5.3e-07
7 Adipose alternative polyA NM_001107743.1 0.03 0.03 3.0e-03 0.02 0.02 0.02 0.02 1.3e-03 6.0e-03 2.2e-03 1.4e-03
8 Adipose mRNA stability Slc43a3 0.09 0.07 3.3e-11 0.08 0.08 0.08 0.08 4.0e-09 2.2e-09 8.1e-09 6.3e-09
9 pVTA gene expression Slc43a3 0.06 0.05 6.8e-06 0.05 0.06 0.06 0.06 1.3e-04 1.1e-05 1.6e-05 8.5e-06
10 Adipose intron excision ratio chr3_90427694_90429546 0.17 0.1 0.0e+00 0.18 0.18 0.18 0.18 4.2e-19 9.5e-20 9.1e-20 1.3e-19
11 Brain mRNA stability Slc43a3 0.03 0.03 4.8e-03 0.02 0.02 0.01 0.02 6.3e-03 9.1e-03 1.4e-02 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.91.65.4-2.3-0.31.41.4-1.31.01.1-1.11.01.00.7
Area under the delay curve2.22.53.6-0.5-0.9-1.5-1.61.7-1.7-1.91.8-1.8-1.8-1.7
BMI with tail0.41.52.30.21.31.51.4-1.41.21.3-1.31.11.21.3
BMI without tail0.30.91.4-0.9-1.0-0.6-0.80.8-1.2-1.10.9-1.1-1.0-1.0
Body weight0.31.52.5-1.3-0.21.61.4-1.31.11.2-1.21.21.21.1
Weight adjusted by age0.30.52.3-1.5-0.80.80.8-0.40.40.4-0.30.50.40.1
Bone surface2.75.07.0-1.60.92.62.5-2.52.22.3-2.42.32.42.2
Bone volume2.74.86.7-2.00.52.62.5-2.52.22.3-2.32.22.32.1
Breakpoint value in progressive ratio session0.40.50.80.40.50.80.9-0.80.70.7-0.70.80.70.7
Number of licking bursts1.32.13.1-1.8-0.41.51.5-1.61.51.5-1.51.61.51.3
Context. condit. distance diff. score0.50.60.9-0.41.00.80.8-0.90.80.9-0.80.60.80.7
Locomotion velocity, session 13.13.34.1-1.20.62.01.9-2.02.02.0-2.01.92.02.0
Locomotion distance, session 10.10.10.20.40.40.30.3-0.30.40.3-0.40.50.40.4
Locomotion velocity, session 20.60.71.0-0.70.10.80.8-0.91.01.0-0.90.90.91.0
Locomotion distance, session 20.50.70.90.8-0.0-1.0-1.00.9-0.8-0.90.9-0.8-0.8-0.8
Locomotion velocity, session 30.40.50.7-0.3-0.5-0.7-0.70.7-0.7-0.70.8-0.8-0.8-0.8
Locomotion distance, session 30.50.61.9-0.6-1.4-0.7-0.70.6-0.6-0.70.7-0.6-0.6-0.7
Stereotopy head waving bouts, day 30.70.91.1-0.10.81.01.0-1.01.01.0-1.00.91.01.1
Stereotopy head waving duration, day 31.01.12.10.31.41.11.1-1.11.11.1-1.11.01.01.1
Locomotion velocity, session 71.51.72.11.40.8-1.3-1.31.3-1.4-1.31.2-1.4-1.4-1.3
Locomotion distance, session 75.77.29.60.4-1.1-2.9-2.92.8-2.9-2.92.9-3.1-3.0-3.0
Stereotopy head waving bouts, day 72.62.93.6-0.50.81.91.9-1.91.91.9-1.91.81.81.9
Stereotopy head waving duration, day 72.93.54.6-0.51.12.12.0-2.12.12.1-2.01.92.02.0
Locomotion velocity, session 80.40.50.7-0.6-0.7-0.7-0.70.6-0.6-0.60.7-0.8-0.7-0.7
Locomotion distance, session 80.40.50.80.80.6-0.8-0.80.7-0.8-0.70.7-0.9-0.7-0.6
Degree of sensitization distance0.80.91.81.01.3-0.9-0.90.8-0.8-0.70.7-1.0-1.0-0.9
Degree of sensitization stereotypy1.92.12.6-0.60.31.61.6-1.61.61.6-1.61.51.51.6
Conditioned locomotion3.03.54.4-1.3-0.12.01.9-2.02.02.0-2.02.12.12.0
Cocaine response after cond. corrected0.30.41.71.3-0.3-0.7-0.70.6-0.6-0.60.5-0.4-0.4-0.4
Cocaine response after cond. not corrected0.40.51.31.2-0.4-0.7-0.80.7-0.7-0.70.6-0.5-0.5-0.6
Cocaine response before conditioning0.10.20.9-0.9-0.10.50.4-0.40.30.3-0.30.20.20.1
Saline control response0.40.60.80.30.40.70.8-0.80.90.8-0.80.90.90.9
Bone: connectivity density0.71.25.0-2.2-0.71.11.1-1.00.80.9-0.90.90.80.4
Bone: cortical apparent density0.10.10.10.30.30.10.3-0.30.20.3-0.30.30.40.1
Bone: cortical area0.00.10.1-0.30.20.30.2-0.20.10.2-0.20.10.30.3
Bone: cortical porosity0.10.10.10.00.1-0.2-0.30.3-0.2-0.20.3-0.3-0.3-0.4
Bone: cortical porosity0.40.40.60.1-0.3-0.6-0.70.7-0.7-0.70.7-0.7-0.7-0.7
Bone: cortical thickness0.20.40.50.6-0.0-0.6-0.70.7-0.7-0.70.7-0.7-0.6-0.6
Bone: cortical thickness1.21.44.42.10.7-1.2-1.21.2-1.0-1.11.0-1.1-1.0-0.8
Bone: cortical tissue density0.00.00.10.20.20.10.2-0.20.10.2-0.20.20.30.0
Condit. Reinf. active minus inactive responses0.00.00.10.30.3-0.2-0.20.1-0.2-0.20.1-0.2-0.2-0.2
Condit. Reinf. active-inactive response ratio0.00.00.0-0.1-0.20.00.1-0.10.10.1-0.10.10.10.1
Condit. Reinf. active responses0.10.20.20.40.3-0.5-0.40.4-0.5-0.40.4-0.5-0.4-0.5
Condit. Reinf. inactive responses0.30.40.50.40.3-0.7-0.60.6-0.7-0.70.6-0.7-0.7-0.7
Incentive salience index mean0.10.10.20.20.40.30.3-0.40.30.3-0.30.30.40.4
Condit. Reinf. lever presses0.00.00.00.1-0.20.00.1-0.0-0.0-0.0-0.00.20.20.1
Condit. Reinf. active minus inactive responses0.50.70.9-0.10.50.90.8-0.80.90.9-0.90.90.90.9
Condit. Reinf. active-inactive response ratio0.10.20.50.70.40.40.3-0.30.30.3-0.40.40.40.5
Condit. Reinf. active responses1.01.51.9-0.80.61.31.3-1.31.41.4-1.31.31.31.2
Condit. Reinf. inactive responses1.01.31.7-0.90.71.11.2-1.31.31.3-1.21.11.11.0
Condit. Reinf. lever presses0.50.61.1-1.10.20.70.9-0.90.90.9-0.80.70.80.6
Condit. Reinf. lever reinforcers received1.01.31.8-0.80.61.21.2-1.31.41.3-1.21.21.21.1
Conditioned reinforcement - actives1.11.98.11.62.81.00.9-1.01.21.2-1.20.91.11.0
Conditioned reinforcement - inactives1.21.73.7-0.11.91.21.3-1.41.31.3-1.41.31.31.4
Conditioned locomotion0.70.96.22.51.60.00.1-0.10.20.3-0.30.20.40.7
Patch foraging indifference point 0 sec0.61.03.5-1.9-1.9-0.4-0.50.6-0.5-0.50.7-0.8-0.9-1.1
Patch foraging indifference point AUC0.30.52.31.51.30.30.2-0.20.10.1-0.40.40.40.7
Delay disc. indifference point, 0s delay2.22.43.5-0.5-0.5-1.5-1.31.6-1.8-1.91.7-1.8-1.7-1.7
Delay disc. indifference point, 16s delay0.10.10.30.10.6-0.1-0.10.4-0.4-0.30.4-0.6-0.5-0.3
Delay disc. indifference point, 2s delay0.60.71.0-0.3-0.1-0.8-0.70.8-0.9-1.00.9-1.0-1.0-1.0
Delay disc. indifference point, 24s delay1.51.710.1-2.8-3.20.30.5-0.20.20.3-0.00.30.2-0.0
Delay disc. indifference point, 4s delay5.15.47.4-0.7-1.2-2.2-2.42.4-2.5-2.52.5-2.7-2.6-2.7
Delay disc. indifference point, 8s delay1.41.72.7-0.2-1.2-1.3-1.41.4-1.3-1.61.4-1.3-1.3-1.2
Indifference point function ln k0.30.53.0-1.7-0.7-0.2-0.10.1-0.2-0.20.3-0.5-0.6-0.8
Indifference point function log k0.30.53.0-1.7-0.7-0.2-0.10.1-0.2-0.20.3-0.5-0.6-0.8
Patch foraging total patch changes 0 sec0.40.84.9-2.2-1.60.10.00.0-0.0-0.00.2-0.3-0.4-0.6
Patch foraging total patch changes 12 sec0.81.01.50.9-0.4-0.9-1.01.1-1.2-1.11.1-1.0-1.1-0.9
Patch foraging total patch changes 18 sec0.50.73.8-1.8-1.9-0.2-0.30.3-0.4-0.30.4-0.3-0.5-0.4
Patch foraging total patch changes 24 sec0.81.31.9-0.4-0.5-1.2-1.41.2-1.1-1.11.2-1.3-1.3-1.3
Patch foraging total patch changes 6 sec1.82.83.41.0-1.0-1.6-1.81.8-1.8-1.91.8-1.9-1.8-1.8
Patch foraging time to switch 0 sec0.40.71.21.1-0.4-1.1-0.90.9-0.7-0.80.9-0.8-0.8-0.8
Patch foraging water rate 0 sec1.22.64.3-2.1-0.31.81.6-1.61.61.6-1.51.71.61.5
Patch foraging water rate 12 sec0.10.21.1-1.1-0.9-0.3-0.30.1-0.0-0.10.3-0.2-0.2-0.4
Patch foraging water rate 18 sec0.00.00.2-0.50.2-0.0-0.0-0.10.20.10.0-0.2-0.1-0.1
Patch foraging water rate 24 sec0.50.74.7-2.2-1.70.20.1-0.0-0.1-0.10.10.0-0.1-0.4
Patch foraging water rate 6 sec0.20.30.90.20.90.50.5-0.50.60.5-0.60.60.50.6
Seeking ratio, delayed vs. immediate footshock0.50.72.51.61.6-0.4-0.40.6-0.6-0.40.5-0.5-0.5-0.5
Distance traveled before self-admin0.50.65.30.8-2.3-0.5-0.40.4-0.3-0.50.30.1-0.1-0.0
Distance traveled after self-admin4.35.36.50.8-2.0-2.5-2.52.4-2.5-2.52.5-2.5-2.4-2.2
Extensor digitorum longus weight0.31.31.6-0.5-1.1-1.2-1.21.2-1.3-1.21.2-1.3-1.1-1.3
Bone: elastic displacement0.80.92.31.50.5-1.0-0.90.9-0.9-0.90.8-0.9-0.8-0.7
Bone: elastic work0.00.00.1-0.2-0.20.20.1-0.10.10.1-0.10.10.20.2
Bone: endosteal estimation0.51.01.5-0.40.91.11.2-1.11.01.0-1.10.91.01.2
Bone: endosteal perimeter1.32.83.6-1.11.61.81.9-1.81.71.7-1.71.51.71.7
Epididymis fat weight0.10.31.11.10.90.40.3-0.50.40.6-0.50.40.40.5
Delta time in closed arm before/after self-admin0.10.10.20.40.3-0.4-0.50.2-0.1-0.10.10.1-0.10.1
Delta time in open arm before/after self-admin0.60.61.20.50.11.11.1-0.90.80.8-0.80.60.80.6
Diff in mean of infusions in LGA sessions0.10.10.3-0.5-0.5-0.1-0.30.2-0.3-0.10.3-0.2-0.3-0.4
Delay discount exponential model param2.52.83.60.71.41.61.6-1.81.71.9-1.81.81.81.8
Extinction: sum of active levers before priming4.95.430.7-5.5-3.81.31.5-1.51.11.4-1.11.41.10.6
Active lever presses in extinction session 61.01.05.9-2.0-2.4-0.30.10.00.0-0.10.3-0.2-0.3-0.6
Bone: final force0.30.52.9-1.5-1.7-0.1-0.20.3-0.3-0.40.4-0.3-0.2-0.3
Bone: final moment0.30.42.3-1.2-1.5-0.1-0.30.3-0.4-0.40.4-0.3-0.2-0.3
Food consumed during 24 hour testing period0.30.41.6-1.3-1.2-0.4-0.40.3-0.3-0.30.5-0.5-0.4-0.5
Glucose0.10.10.80.30.90.10.2-0.10.20.1-0.1-0.00.00.1
Heart weight2.23.45.30.0-0.3-2.1-2.01.9-2.0-1.81.9-2.3-2.1-2.1
Delay discount hyperbolic model param2.73.04.00.51.21.71.8-1.81.82.0-1.91.91.91.9
Intermittent access intake day 1-15 change1.12.211.5-3.4-1.81.31.2-1.21.11.1-0.90.90.70.6
Intermittent access intake escalation1.32.613.5-3.7-2.31.31.2-1.21.11.1-0.90.90.70.6
Intermittent access intake escalation 20.50.52.8-1.5-1.7-0.0-0.20.2-0.1-0.10.3-0.4-0.5-0.5
Intermitt. access day 1 inactive lever presses1.03.918.8-4.3-3.8-0.8-0.60.6-0.9-1.01.1-1.1-1.3-1.5
Intermitt. access day 15 inactive lever presses0.91.711.4-3.4-2.30.70.8-0.70.50.4-0.40.50.40.1
Intermitt. access escalation Index2.63.717.34.22.6-1.5-1.51.6-1.5-1.51.2-1.2-1.3-1.0
Intermittent access day 1 total infusions1.72.73.4-0.81.21.91.8-1.81.81.8-1.81.61.71.5
Intermittent access day 15 total infusions2.84.214.5-3.8-1.52.02.0-2.02.02.0-1.71.71.51.2
Intermittent access terminal intake (last 3 days)2.83.711.7-3.4-1.01.91.9-1.92.02.0-1.81.71.51.2
Intermittent access total infusions2.32.77.9-2.8-0.41.81.7-1.71.71.7-1.61.41.31.1
Intermittent access day 1 locomotion0.40.62.1-1.4-0.70.70.7-0.80.70.7-0.60.60.50.3
Intermittent access day 15 total locomotion1.62.93.7-1.60.21.91.9-1.91.81.8-1.81.71.81.7
Intermittent access total locomotion3.74.513.0-3.6-1.42.12.0-2.12.12.1-1.91.81.81.6
Intermittent access standard deviation1.22.67.0-2.6-0.91.71.7-1.71.41.5-1.51.41.31.2
Left kidney weight0.31.44.7-2.2-2.1-0.6-0.70.7-0.9-0.60.9-1.0-0.9-1.2
Right kidney weight0.00.00.0-0.20.10.10.1-0.1-0.10.2-0.1-0.2-0.1-0.2
Cocaine induced anxiety0.10.21.41.20.60.1-0.20.2-0.1-0.10.10.00.00.1
Post-drug Anxiety0.20.21.11.01.00.40.3-0.20.20.2-0.20.20.30.5
Baseline Anxiety0.20.31.20.61.10.10.4-0.40.40.4-0.40.30.40.7
Tail length0.51.87.1-2.4-2.7-0.7-0.90.8-1.1-0.91.0-0.8-0.8-1.0
Length with tail0.41.711.6-3.4-2.50.50.4-0.50.30.4-0.30.50.40.0
Length without tail0.82.63.4-0.70.71.71.8-1.81.91.8-1.81.81.71.6
Times rat made contact with spout1.11.21.6-0.40.61.21.2-1.21.21.2-1.21.21.31.1
Lifetime Intake1.41.79.0-3.0-0.61.21.1-1.21.21.1-1.00.90.80.4
Liver weight, left0.10.21.4-1.2-0.60.00.0-0.0-0.1-0.10.1-0.2-0.1-0.3
Liver weight, right1.62.86.2-2.5-0.21.91.8-1.81.71.7-1.61.61.61.3
Locomotor activity0.30.40.7-0.30.90.50.4-0.60.70.6-0.70.70.70.7
Locomotor testing distance0.40.73.9-2.0-0.50.70.4-0.60.70.6-0.70.70.70.5
Locomotor testing rearing0.10.30.9-0.9-0.40.40.1-0.30.30.4-0.40.70.50.5
Locomotion in novel chamber1.41.84.52.1-0.1-1.4-1.11.3-1.6-1.31.2-1.3-1.2-1.0
Locomotion in novel chamber post-restriction1.72.810.33.21.4-1.5-1.51.5-1.6-1.41.3-1.7-1.4-1.0
Fecal boli incidents, locomotor time 11.21.82.80.5-0.7-1.5-1.61.7-1.3-1.31.6-1.4-1.4-1.2
Change in fecal boli incidents, locomotor task1.11.16.5-2.6-2.30.20.1-0.1-0.1-0.10.1-0.1-0.0-0.4
Time >=10cm from walls, locomotor time 10.80.81.90.3-1.4-1.0-0.90.9-1.0-0.70.8-0.7-0.8-0.9
Bouts of movement, locomotor time 10.10.10.5-0.7-0.3-0.3-0.10.1-0.1-0.00.3-0.50.0-0.1
Total resting periods, locomotor time 10.10.10.3-0.5-0.00.10.3-0.20.30.3-0.1-0.10.40.3
Rest time, locomotor task time 13.84.710.9-3.3-0.32.42.2-2.22.32.3-2.02.01.91.7
Distance moved, locomotor task time 10.60.98.62.90.5-0.5-0.40.6-0.5-0.60.3-0.2-0.20.1
Vertical activity count, locomotor time 10.00.10.80.9-0.2-0.10.2-0.0-0.3-0.3-0.10.10.10.3
Time >=10cm from walls, locomotor time 21.31.913.6-2.6-3.70.0-0.1-0.20.40.40.00.30.2-0.3
Bouts of movement, locomotor time 20.91.412.6-3.6-1.10.60.8-0.60.10.5-0.30.00.1-0.2
Total resting periods, locomotor time 21.01.713.7-3.7-0.71.01.1-0.90.40.8-0.60.30.40.1
Rest time, locomotor task time 23.24.016.0-4.0-0.52.12.1-1.71.61.6-1.61.81.81.5
Distance moved, locomotor task time 20.91.11.91.0-1.4-1.1-1.11.0-0.9-1.11.0-0.9-0.9-0.9
Vertical activity count, locomotor time 20.30.42.8-0.4-1.7-0.5-0.30.3-0.4-0.50.4-0.3-0.4-0.4
Light reinforcement 11.63.95.7-2.4-0.91.92.1-2.02.12.0-2.02.12.11.8
Light reinforcement 21.21.92.51.11.51.01.2-1.41.51.4-1.51.51.51.6
Bone: marrow area0.40.81.2-0.40.81.01.1-1.00.90.9-1.00.80.91.1
Bone: maximum diameter0.91.62.0-1.10.51.41.4-1.41.31.3-1.31.21.41.4
Bone: maximum force0.50.85.5-2.3-1.60.50.3-0.30.30.3-0.20.30.40.1
Bone: maximum moment0.30.64.1-2.0-1.30.50.3-0.30.20.2-0.20.20.30.2
Mean time between licks in bursts0.10.31.00.41.00.50.5-0.50.40.4-0.50.40.50.7
Mean num. licks in bursts0.20.31.81.31.0-0.3-0.30.3-0.2-0.20.3-0.4-0.2-0.1
Cd content in liver2.32.55.5-1.9-2.3-1.4-1.41.3-1.3-1.31.5-1.6-1.5-1.7
Co content in liver4.45.16.20.9-2.3-2.5-2.42.5-2.4-2.42.5-2.2-2.2-2.1
Cu content in liver0.10.10.20.0-0.3-0.3-0.40.4-0.4-0.40.4-0.2-0.3-0.3
Fe content in liver0.40.50.8-0.7-0.40.80.7-0.70.90.8-0.80.90.70.5
K content in liver0.30.30.6-0.0-0.8-0.4-0.60.6-0.5-0.60.5-0.3-0.5-0.5
Mg content in liver1.31.31.70.6-0.5-1.2-1.31.3-1.3-1.31.3-1.2-1.3-1.1
Mn content in liver0.20.20.91.00.6-0.4-0.50.5-0.4-0.40.4-0.4-0.4-0.2
Na content in liver1.51.65.9-2.4-0.11.31.1-1.21.21.2-1.21.11.00.8
Rb content in liver3.84.45.10.4-2.2-2.3-2.22.2-2.3-2.32.3-2.1-2.1-2.1
Se content in liver0.91.11.9-0.3-0.31.11.0-1.11.01.0-1.11.41.21.3
Sr content in liver0.60.51.00.41.00.70.7-0.70.70.7-0.70.70.70.8
Zn content in liver1.11.21.6-0.3-0.7-1.2-1.21.2-1.2-1.11.2-1.3-1.2-1.2
Bone: minimum diameter0.00.10.3-0.40.50.20.2-0.10.00.0-0.1-0.10.20.1
Time in familiar zone, hab. session 10.20.21.1-1.1-0.70.20.2-0.20.10.2-0.10.20.1-0.1
Time in novel zone, hab. session 10.30.30.40.10.40.50.5-0.50.60.5-0.50.40.60.6
Total zone transitions, hab. session 11.11.61.90.7-0.8-1.4-1.41.4-1.4-1.31.3-1.3-1.4-1.3
Total locomotion distance, hab. session 10.81.21.7-0.7-1.1-1.0-1.01.0-1.1-1.01.1-1.2-1.2-1.3
Locomotion velocity, hab. session 11.11.62.3-0.3-1.0-1.3-1.31.3-1.3-1.31.3-1.4-1.5-1.5
Time in familiar zone, hab. session 21.51.62.01.4-0.9-1.4-1.41.4-1.2-1.31.3-1.1-1.3-1.1
Time in novel zone, hab. session 20.50.50.7-0.80.60.80.8-0.80.70.7-0.70.60.70.6
Total zone transitions, hab. session 21.41.82.31.4-0.2-1.5-1.51.5-1.3-1.41.4-1.4-1.5-1.2
Total locomotion distance, hab. session 20.40.50.80.2-0.2-0.8-0.80.8-0.8-0.80.8-0.9-0.9-0.8
Locomotion velocity, hab. session 20.30.50.80.2-0.0-0.7-0.70.7-0.7-0.70.7-0.8-0.9-0.8
Novel to familiar place preference ratio0.20.20.8-0.00.90.40.4-0.40.40.4-0.40.30.30.2
Novelty place preference0.20.20.80.00.90.40.4-0.40.40.4-0.40.30.30.2
Time in novel zone, NPP test0.10.10.60.20.80.00.0-0.00.0-0.0-0.0-0.1-0.1-0.1
Total zone transitions, NPP test1.42.02.50.3-1.3-1.6-1.61.5-1.4-1.51.5-1.4-1.5-1.6
Total locomotion distance, NPP test0.10.10.10.30.1-0.2-0.30.3-0.3-0.30.2-0.2-0.3-0.3
Locomotion velocity, NPP test0.00.00.10.40.30.10.1-0.10.10.1-0.10.20.10.1
Intraocular pressure0.10.10.50.60.7-0.1-0.20.20.1-0.20.1-0.1-0.1-0.1
Delta distance traveled before/after self-admin4.34.57.80.70.9-2.1-2.02.1-2.3-2.12.2-2.8-2.6-2.4
Delta ambulatory time before/after self-admin3.44.27.60.81.1-2.0-1.92.0-2.2-1.92.1-2.8-2.5-2.3
Parametrial fat weight0.81.89.3-3.1-1.21.51.4-1.10.80.9-0.90.80.80.5
Pavlov. Cond. lever latency0.00.10.3-0.60.00.20.2-0.20.20.3-0.20.10.10.1
Pavlov. Cond. magazine entry latency0.10.10.20.4-0.1-0.3-0.30.4-0.3-0.40.3-0.4-0.4-0.4
Pavlov. Cond. change in total contacts0.10.21.61.20.3-0.1-0.10.1-0.1-0.20.10.1-0.00.1
Pavlov. Cond. index score0.10.10.60.80.0-0.2-0.10.2-0.1-0.20.1-0.1-0.1-0.1
Pavlov. Cond. latency score0.00.10.40.6-0.2-0.2-0.20.2-0.2-0.30.2-0.1-0.1-0.1
Pavlov. Cond. lever contacts0.00.00.50.70.2-0.0-0.00.1-0.1-0.10.00.10.0-0.0
Pavlov. Cond. magazine entry number0.10.21.3-1.1-0.5-0.1-0.10.0-0.1-0.00.1-0.2-0.1-0.2
Pavlov. Cond. intertrial magazine entries0.30.30.7-0.4-0.8-0.6-0.60.5-0.6-0.60.6-0.4-0.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.60.8-0.2-0.4-0.40.4-0.3-0.40.3-0.3-0.3-0.3
Pavlov. Cond. response bias0.10.21.51.20.7-0.1-0.00.1-0.1-0.10.00.0-0.1-0.0
Pavlov. Cond. lever latency0.60.91.6-0.7-1.3-0.7-0.90.9-0.9-0.90.9-0.9-0.9-1.0
Pavlov. Cond. magazine entry latency3.74.55.20.32.32.22.2-2.22.22.2-2.32.22.22.2
Pavlov. Cond. change in total contacts0.50.91.50.61.20.70.9-0.90.90.9-0.90.91.01.1
Pavlov. Cond. index score2.02.64.50.82.11.51.6-1.61.61.7-1.71.61.61.7
Pavlov. Cond. latency score1.82.43.80.72.01.51.6-1.61.61.6-1.61.51.61.7
Pavlov. Cond. lever contacts1.11.52.80.81.71.01.2-1.21.21.2-1.21.21.21.3
Pavlov. Cond. magazine entry number2.73.45.5-0.8-2.3-1.8-1.81.8-1.9-1.91.9-1.8-1.9-1.9
Pavlov. Cond. intertrial magazine entries0.30.41.1-0.6-1.1-0.5-0.50.5-0.6-0.60.6-0.5-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.92.54.50.82.11.51.6-1.61.61.6-1.61.51.61.7
Pavlov. Cond. response bias2.02.74.71.02.21.51.6-1.61.61.7-1.71.61.61.7
Time in closed arm before self-admin1.01.38.93.02.3-0.1-0.20.3-0.2-0.1-0.1-0.00.30.3
Time in closed arm after self-admin2.02.14.72.21.0-1.6-1.71.6-1.3-1.41.3-1.2-1.1-1.0
Time in open arm before self-admin0.60.61.1-0.8-1.0-0.8-0.80.7-0.9-0.60.8-0.5-0.9-0.7
Time in open arm after self-admin0.80.81.3-0.9-0.61.11.1-1.10.91.0-0.90.80.70.8
Bone: periosteal estimation0.40.81.1-0.50.81.01.0-1.00.90.9-0.90.81.01.1
Bone: periosteal perimeter0.71.21.6-0.60.91.21.2-1.21.11.1-1.11.01.21.2
Bone: post-yield work0.20.30.8-0.9-0.10.50.4-0.40.50.5-0.40.50.50.4
Progressive ratio test 1 active lever presses1.72.15.90.52.41.51.5-1.41.31.3-1.51.21.31.2
Progressive ratio test 1 breakpoint1.62.05.70.62.41.51.4-1.41.31.2-1.41.21.21.1
Progressive ratio test 1 inactive lever presses1.72.53.5-1.91.41.71.8-1.71.41.4-1.61.51.41.4
Progressive ratio test 2 active lever presses2.52.94.5-2.10.02.02.0-1.91.81.8-1.81.61.51.3
Progressive ratio test 2 breakpoint2.63.04.9-2.2-0.12.02.0-1.91.81.8-1.81.61.51.3
Progressive ratio test 2 inactive lever presses0.40.73.0-1.7-0.90.80.7-0.80.70.8-0.70.50.50.3
Incentive Sensitization - Responses3.44.810.5-3.2-1.62.22.2-2.22.22.2-2.02.11.91.7
Incentive Sensitization - Breakpoint4.05.211.1-3.3-1.52.42.3-2.32.32.3-2.12.22.01.8
Sum of active levers in priming session hrs 5-66.15.739.8-6.3-3.81.11.4-1.31.11.1-0.70.70.5-0.0
Progressive ratio0.61.08.0-1.5-2.8-0.30.30.3-0.2-0.40.40.0-0.3-0.5
Food seeking constrained by brief footshock0.30.30.80.50.2-0.7-0.50.4-0.6-0.40.4-0.8-0.6-0.9
Seeking ratio, punishment vs. effort0.71.06.91.82.60.2-0.3-0.10.30.2-0.30.00.30.3
Retroperitoneal fat weight1.56.48.7-2.2-0.03.02.7-2.82.52.8-2.72.62.62.5
Reaction time number correct0.30.62.71.60.1-0.8-0.70.7-0.5-0.50.7-0.6-0.5-0.5
Reaction time mean minus median0.20.41.80.11.30.70.6-0.60.50.6-0.60.50.30.4
Reaction time mean minus median AUC0.30.74.12.01.9-0.1-0.10.2-0.1-0.2-0.00.0-0.10.1
Reaction time num false alarms0.10.10.4-0.5-0.6-0.2-0.20.1-0.1-0.10.1-0.2-0.3-0.4
Reaction time num false alarms AUC0.10.10.4-0.5-0.7-0.3-0.30.3-0.3-0.30.3-0.3-0.4-0.5
Reaction time trials correct on left0.30.62.71.60.1-0.8-0.70.7-0.5-0.50.7-0.6-0.5-0.5
Reaction time trials on left0.30.52.81.70.2-0.7-0.70.6-0.5-0.50.6-0.5-0.5-0.5
Reaction time mean3.25.17.71.22.82.02.2-2.22.32.3-2.42.32.32.5
Reaction time mean AUC3.14.99.62.03.11.92.0-2.02.22.1-2.22.12.22.4
Median of all reaction times4.76.68.81.42.92.32.4-2.52.72.6-2.72.72.83.0
Reaction time omissions1.31.82.70.11.11.31.4-1.41.61.5-1.51.51.41.4
Reaction time false alarm rate0.30.42.7-1.6-0.60.50.4-0.50.40.4-0.40.40.20.1
Reaction time premature initiation rate1.11.510.5-3.2-2.30.0-0.10.1-0.3-0.10.3-0.0-0.5-0.6
Reaction time premature initiations0.50.84.0-2.0-1.8-0.3-0.40.4-0.5-0.40.5-0.3-0.6-0.7
Std. dev. reaction times0.40.83.20.71.80.70.7-0.70.80.8-0.90.80.60.7
Reaction time trials completed0.30.52.81.70.2-0.7-0.70.6-0.5-0.50.6-0.5-0.5-0.5
Reaction time trials AUC0.30.63.01.70.0-0.8-0.70.7-0.5-0.50.6-0.5-0.5-0.5
Run reversals in cocaine runway, females0.70.71.5-0.9-1.2-0.6-0.50.8-0.7-0.90.8-0.6-0.8-1.0
Run reversals in cocaine runway, males2.02.03.01.51.61.41.2-1.11.51.1-1.31.61.51.7
Latency to leave start box in cocaine runway3.03.54.9-0.9-0.02.02.0-1.92.01.9-1.92.22.12.1
Latency to leave start box in cocaine runway, F2.83.25.1-2.3-0.22.11.8-1.91.71.8-1.81.81.81.7
Latency to leave start box in cocaine runway, M1.91.73.61.90.81.01.3-1.01.41.0-1.11.61.51.7
Std. dev. time between licks in bursts1.31.72.70.8-0.2-1.4-1.41.4-1.4-1.41.4-1.6-1.5-1.3
Total sessions with >9 infusions0.91.19.8-3.1-0.30.70.7-0.70.40.4-0.40.30.3-0.1
Short access day 1 total inactive lever presses0.70.96.4-2.5-1.7-0.3-0.30.1-0.1-0.10.30.0-0.2-0.3
Short access day 10 total inactive lever presses0.10.20.8-0.9-0.9-0.3-0.10.2-0.3-0.20.2-0.1-0.3-0.3
Short access day 1 total infusions0.60.87.0-2.6-1.4-0.1-0.20.0-0.0-0.10.2-0.0-0.2-0.6
Short access day 10 total infusions0.91.22.7-1.60.41.11.1-1.21.11.0-1.11.01.00.8
Short access total infusions0.30.43.6-1.9-0.30.30.2-0.30.30.3-0.30.20.2-0.2
Short access day 1 locomotion1.21.511.4-3.4-2.00.30.3-0.50.40.4-0.20.20.2-0.1
Short access day 10 total locomotion1.22.28.7-3.0-1.11.41.5-1.41.31.2-1.21.11.10.9
Short access total locomotion1.21.58.8-3.0-1.20.90.9-1.00.80.8-0.80.70.70.4
One hour access (0.3 mA shock)0.40.51.91.41.10.40.4-0.40.50.5-0.60.40.40.6
Compulsive drug intake1.41.62.51.60.3-1.5-1.41.4-1.4-1.41.3-1.2-1.2-1.0
One hour access (shock baseline)0.91.42.0-1.4-0.31.31.2-1.21.31.3-1.21.11.11.0
Social response proportion0.20.20.70.8-0.1-0.3-0.40.5-0.3-0.50.4-0.3-0.2-0.2
Social responses0.60.81.00.00.90.90.8-0.81.00.8-0.91.01.01.0
Social time0.20.30.50.0-0.20.60.6-0.40.70.5-0.50.70.60.5
Soleus weight1.54.45.8-1.10.82.32.4-2.32.32.2-2.32.12.32.2
Bone: stiffness0.30.52.2-1.5-0.80.70.6-0.60.50.5-0.50.50.60.4
Tibialis anterior weight0.41.52.20.4-0.6-1.3-1.21.3-1.4-1.41.3-1.5-1.3-1.3
Time to tail flick, vehicle, before self-admin2.32.316.1-4.0-2.8-0.3-0.20.1-0.1-0.20.5-0.6-0.4-0.9
Time to tail flick, vehicle, after self-admin0.81.07.9-1.3-2.80.20.00.00.30.0-0.10.90.80.2
Time to tail flick, test, before self-admin1.92.02.5-0.81.51.51.3-1.41.41.6-1.41.41.51.4
Time to tail flick, test, after self-admin0.20.20.91.00.8-0.1-0.40.3-0.1-0.20.00.40.30.1
Delta time to tail flick, vehicle, before/after SA0.30.20.90.6-0.50.10.0-0.10.30.1-0.31.00.70.6
Delta time to tail flick, test, before/after SA2.32.43.31.4-0.6-1.7-1.81.7-1.6-1.81.6-1.3-1.5-1.5
Tibia length0.30.85.82.41.8-0.1-0.10.1-0.1-0.1-0.0-0.10.10.2
Ambulatory time before self-admin1.21.712.00.5-3.5-1.1-1.01.0-0.9-1.10.9-0.3-0.6-0.6
Ambulatory time after self-admin3.74.35.31.2-1.7-2.3-2.22.2-2.2-2.22.2-2.3-2.2-1.9
Bone: tissue strength0.40.42.1-1.4-0.60.60.5-0.50.50.5-0.50.50.50.3
Total heroin consumption1.11.34.7-1.3-2.20.90.9-1.01.11.1-0.81.00.80.7
Bone: trabecular number0.91.54.2-2.1-0.11.41.4-1.31.11.2-1.21.11.00.6
Bone: trabecular spacing0.71.01.40.9-0.4-1.2-1.11.1-1.1-1.11.1-1.0-0.9-0.7
Bone: trabecular thickness0.40.50.8-0.50.60.90.9-0.80.70.7-0.80.60.70.6
Bone: trabecular tissue density0.60.93.71.91.80.40.5-0.50.60.6-0.70.60.60.9
Water consumed over 24 hours0.30.41.2-1.1-0.70.50.5-0.50.60.6-0.50.60.60.5
Number of responses in last shaping day0.50.62.80.21.70.60.8-0.60.50.4-0.60.70.60.5