Slc43a3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	Slc43a3	0.49	0.02	1.3e-03	-0	0.04	0.01	-0	7.0e-01	1.1e-05	2.2e-02	8.3e-01
2	Liver	isoform ratio	XM_017591713.3	0.5	0.02	9.4e-03	0.01	0	0.01	0.01	4.3e-02	1.4e-01	8.3e-03	3.6e-02
3	Adipose	isoform ratio	XM_017591713.3	0.26	0.12	5.0e-09	0.07	0.06	0.06	0.06	4.4e-08	2.0e-07	1.6e-07	1.1e-07
4	Adipose	intron excision ratio	chr3_90422494_90426224	0.32	0.09	8.8e-10	0.07	0.07	0.07	0.07	2.0e-08	6.8e-08	6.0e-08	5.9e-08
5	PL	isoform ratio	XM_039104888.1	0.03	0.04	2.9e-03	0.02	0.02	0.02	0.02	3.2e-03	3.1e-03	4.3e-03	4.7e-03
6	Liver	intron excision ratio	chr3_90427694_90429546	0.07	0.06	3.9e-08	0.06	0.05	0.05	0.06	4.8e-07	1.6e-06	1.1e-06	5.4e-07
7	Adipose	alternative polyA	NM_001107743.1	0.03	0.03	3.0e-03	0.02	0.02	0.02	0.02	1.3e-03	6.0e-03	2.1e-03	1.5e-03
8	Adipose	mRNA stability	Slc43a3	0.09	0.07	3.3e-11	0.08	0.08	0.08	0.08	4.0e-09	2.2e-09	8.1e-09	6.8e-09
9	pVTA	gene expression	Slc43a3	0.06	0.05	6.8e-06	0.05	0.06	0.06	0.06	1.3e-04	1.1e-05	1.6e-05	8.6e-06
10	Adipose	intron excision ratio	chr3_90427694_90429546	0.17	0.1	0.0e+00	0.18	0.18	0.18	0.18	4.2e-19	9.5e-20	9.1e-20	1.2e-19
11	Brain	mRNA stability	Slc43a3	0.03	0.03	4.8e-03	0.02	0.02	0.01	0.02	6.3e-03	9.1e-03	1.4e-02	1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.9	1.6	5.4	-2.3	0.7	-1.4	-1.4	-1.3	-1.0	-1.1	-1.1	1.0	-1.0	-0.7
Area under the delay curve	1.6	2.5	3.6	-0.5	0.7	1.5	1.6	1.7	1.7	1.9	1.8	-1.8	1.8	1.7
BMI with tail	0.4	1.4	2.3	0.2	-0.8	-1.5	-1.4	-1.4	-1.2	-1.3	-1.3	1.1	-1.2	-1.3
BMI without tail	0.2	0.9	1.4	-0.9	0.8	0.6	0.8	0.8	1.2	1.1	0.9	-1.1	1.0	1.0
Body weight	0.3	1.5	2.5	-1.3	0.7	-1.6	-1.4	-1.3	-1.1	-1.2	-1.2	1.2	-1.2	-1.1
Weight adjusted by age	0.2	0.6	2.3	-1.5	1.2	-0.8	-0.8	-0.4	-0.4	-0.4	-0.3	0.5	-0.4	-0.1
Bone surface	2.5	4.9	7.0	-1.6	-0.1	-2.6	-2.5	-2.5	-2.2	-2.3	-2.4	2.3	-2.4	-2.2
Bone volume	2.4	4.8	6.7	-2.0	0.2	-2.6	-2.5	-2.5	-2.2	-2.3	-2.3	2.2	-2.3	-2.1
Breakpoint value in progressive ratio session	0.3	0.5	0.8	0.4	-0.4	-0.8	-0.9	-0.8	-0.7	-0.7	-0.7	0.8	-0.6	-0.7
Number of licking bursts	0.7	2.2	3.1	-1.8	1.0	-1.5	-1.5	-1.6	-1.5	-1.5	-1.5	1.6	-1.5	-1.3
Context. condit. distance diff. score	0.5	0.6	0.8	-0.4	-0.8	-0.8	-0.8	-0.9	-0.8	-0.9	-0.8	0.6	-0.8	-0.7
Locomotion velocity, session 1	2.9	3.3	4.1	-1.2	0.1	-2.0	-1.9	-2.0	-2.0	-2.0	-2.0	1.9	-2.0	-2.0
Locomotion distance, session 1	0.1	0.1	0.2	0.4	-0.3	-0.3	-0.3	-0.3	-0.4	-0.3	-0.4	0.5	-0.4	-0.4
Locomotion velocity, session 2	0.6	0.7	1.0	-0.7	0.3	-0.8	-0.8	-0.9	-1.0	-1.0	-0.9	0.9	-0.9	-1.0
Locomotion distance, session 2	0.5	0.7	0.9	0.8	-0.3	1.0	1.0	0.9	0.8	0.9	0.9	-0.8	0.8	0.8
Locomotion velocity, session 3	0.4	0.5	0.7	-0.3	0.3	0.7	0.7	0.7	0.7	0.7	0.8	-0.8	0.8	0.8
Locomotion distance, session 3	0.5	0.5	1.8	-0.6	1.3	0.7	0.7	0.6	0.6	0.7	0.7	-0.6	0.6	0.7
Stereotopy head waving bouts, day 3	0.7	0.8	1.1	-0.1	-0.5	-1.0	-1.0	-1.0	-1.0	-1.0	-1.0	0.9	-1.0	-1.1
Stereotopy head waving duration, day 3	0.9	1.1	1.6	0.3	-1.3	-1.1	-1.1	-1.1	-1.1	-1.1	-1.1	1.0	-1.0	-1.1
Locomotion velocity, session 7	1.6	1.8	2.1	1.4	-1.4	1.3	1.3	1.3	1.4	1.3	1.2	-1.4	1.4	1.3
Locomotion distance, session 7	5.6	7.1	9.6	0.4	0.1	2.9	2.9	2.8	2.9	2.9	2.9	-3.1	3.0	3.0
Stereotopy head waving bouts, day 7	2.5	2.9	3.6	-0.5	-0.2	-1.9	-1.9	-1.9	-1.9	-1.9	-1.9	1.8	-1.8	-1.9
Stereotopy head waving duration, day 7	2.8	3.4	4.6	-0.5	-0.5	-2.1	-2.0	-2.1	-2.1	-2.1	-2.0	1.9	-2.0	-2.0
Locomotion velocity, session 8	0.4	0.4	0.7	-0.6	0.5	0.7	0.7	0.6	0.6	0.6	0.7	-0.8	0.7	0.7
Locomotion distance, session 8	0.4	0.6	0.8	0.8	-0.9	0.8	0.8	0.7	0.8	0.7	0.7	-0.9	0.7	0.6
Degree of sensitization distance	0.9	1.0	3.5	1.0	-1.9	0.9	0.9	0.8	0.8	0.7	0.7	-1.0	1.0	0.9
Degree of sensitization stereotypy	1.9	2.1	2.6	-0.6	0.3	-1.6	-1.6	-1.6	-1.6	-1.6	-1.6	1.5	-1.5	-1.6
Conditioned locomotion	3.0	3.5	4.4	-1.3	0.9	-2.0	-1.9	-2.0	-2.0	-2.0	-2.0	2.1	-2.1	-2.0
Cocaine response after cond. corrected	0.3	0.4	1.7	1.3	0.1	0.7	0.7	0.6	0.6	0.6	0.5	-0.4	0.4	0.4
Cocaine response after cond. not corrected	0.3	0.5	1.3	1.2	0.2	0.7	0.8	0.7	0.7	0.7	0.6	-0.5	0.5	0.6
Cocaine response before conditioning	0.1	0.2	0.9	-0.9	0.2	-0.5	-0.4	-0.4	-0.3	-0.3	-0.3	0.2	-0.2	-0.1
Saline control response	0.4	0.6	0.8	0.3	-0.0	-0.7	-0.8	-0.8	-0.9	-0.8	-0.8	0.9	-0.9	-0.9
Bone: connectivity density	0.8	1.2	5.0	-2.2	1.1	-1.1	-1.1	-1.0	-0.8	-0.9	-0.9	0.9	-0.8	-0.4
Bone: cortical apparent density	0.0	0.1	0.1	0.3	-0.3	-0.1	-0.3	-0.3	-0.2	-0.3	-0.3	0.3	-0.4	-0.1
Bone: cortical area	0.0	0.0	0.1	-0.3	-0.1	-0.3	-0.2	-0.2	-0.1	-0.2	-0.2	0.1	-0.3	-0.3
Bone: cortical porosity	0.1	0.1	0.1	0.0	-0.2	0.2	0.3	0.3	0.2	0.2	0.3	-0.3	0.3	0.4
Bone: cortical porosity	0.4	0.4	0.6	0.1	0.0	0.6	0.7	0.7	0.7	0.7	0.7	-0.7	0.7	0.7
Bone: cortical thickness	0.2	0.4	0.5	0.6	-0.2	0.6	0.7	0.7	0.7	0.7	0.7	-0.7	0.6	0.6
Bone: cortical thickness	1.2	1.5	4.4	2.1	-1.2	1.2	1.2	1.2	1.0	1.1	1.0	-1.1	1.0	0.8
Bone: cortical tissue density	0.0	0.0	0.1	0.2	-0.1	-0.1	-0.2	-0.2	-0.1	-0.2	-0.2	0.2	-0.3	-0.0
Condit. Reinf. active minus inactive responses	0.0	0.0	0.1	0.3	-0.4	0.2	0.2	0.1	0.2	0.2	0.1	-0.2	0.2	0.2
Condit. Reinf. active-inactive response ratio	0.0	0.0	0.1	-0.1	0.2	-0.0	-0.1	-0.1	-0.1	-0.1	-0.1	0.1	-0.1	-0.1
Condit. Reinf. active responses	0.2	0.2	0.3	0.4	-0.5	0.5	0.4	0.4	0.5	0.4	0.4	-0.5	0.4	0.5
Condit. Reinf. inactive responses	0.3	0.4	0.5	0.4	-0.6	0.7	0.6	0.6	0.7	0.7	0.6	-0.7	0.7	0.7
Incentive salience index mean	0.1	0.1	0.1	0.2	-0.3	-0.3	-0.3	-0.4	-0.3	-0.3	-0.3	0.3	-0.4	-0.4
Condit. Reinf. lever presses	0.0	0.0	0.1	0.1	0.2	-0.0	-0.1	-0.0	0.0	0.0	-0.0	0.2	-0.2	-0.1
Condit. Reinf. active minus inactive responses	0.4	0.6	0.9	-0.1	-0.3	-0.9	-0.8	-0.8	-0.9	-0.9	-0.9	0.9	-0.9	-0.9
Condit. Reinf. active-inactive response ratio	0.1	0.2	0.5	0.7	-0.3	-0.4	-0.3	-0.3	-0.3	-0.3	-0.4	0.4	-0.4	-0.5
Condit. Reinf. active responses	1.0	1.4	1.9	-0.8	-0.3	-1.3	-1.3	-1.3	-1.4	-1.4	-1.3	1.3	-1.3	-1.2
Condit. Reinf. inactive responses	0.8	1.2	1.7	-0.9	-0.5	-1.1	-1.2	-1.3	-1.3	-1.3	-1.2	1.1	-1.1	-1.0
Condit. Reinf. lever presses	0.4	0.6	1.1	-1.1	0.1	-0.7	-0.9	-0.9	-0.9	-0.9	-0.8	0.7	-0.8	-0.6
Condit. Reinf. lever reinforcers received	0.9	1.3	1.8	-0.8	-0.3	-1.2	-1.2	-1.3	-1.4	-1.3	-1.2	1.2	-1.2	-1.1
Conditioned reinforcement - actives	0.4	1.7	6.8	1.6	-2.6	-1.0	-0.9	-1.0	-1.2	-1.2	-1.2	0.9	-1.1	-1.0
Conditioned reinforcement - inactives	0.6	1.7	3.0	-0.1	-1.7	-1.2	-1.3	-1.4	-1.3	-1.3	-1.4	1.3	-1.3	-1.4
Conditioned locomotion	0.6	0.9	6.2	2.5	-1.7	-0.0	-0.1	-0.1	-0.2	-0.3	-0.3	0.2	-0.4	-0.7
Patch foraging indifference point 0 sec	0.4	1.0	3.5	-1.9	1.9	0.4	0.5	0.6	0.5	0.5	0.7	-0.8	0.9	1.1
Patch foraging indifference point AUC	0.2	0.5	2.3	1.5	-1.3	-0.3	-0.2	-0.2	-0.1	-0.1	-0.4	0.4	-0.4	-0.7
Delay disc. indifference point, 0s delay	2.1	2.3	3.5	-0.5	0.1	1.5	1.3	1.6	1.8	1.9	1.7	-1.8	1.7	1.7
Delay disc. indifference point, 16s delay	0.1	0.1	0.3	0.1	-0.5	0.1	0.1	0.4	0.4	0.3	0.4	-0.6	0.5	0.3
Delay disc. indifference point, 2s delay	0.6	0.7	1.0	-0.3	-0.2	0.8	0.7	0.8	0.9	1.0	0.9	-1.0	1.0	1.0
Delay disc. indifference point, 24s delay	1.3	2.1	14.3	-2.8	3.8	-0.3	-0.5	-0.2	-0.2	-0.3	-0.0	0.3	-0.2	0.0
Delay disc. indifference point, 4s delay	5.0	5.3	7.4	-0.7	0.6	2.2	2.4	2.4	2.5	2.5	2.5	-2.7	2.6	2.7
Delay disc. indifference point, 8s delay	1.0	1.6	2.7	-0.2	1.1	1.3	1.4	1.4	1.3	1.6	1.4	-1.3	1.3	1.2
Indifference point function ln k	0.2	0.5	3.0	-1.7	0.7	0.2	0.1	0.1	0.2	0.2	0.3	-0.5	0.6	0.8
Indifference point function log k	0.2	0.5	3.0	-1.7	0.7	0.2	0.1	0.1	0.2	0.2	0.3	-0.5	0.6	0.8
Patch foraging total patch changes 0 sec	0.3	0.8	4.9	-2.2	1.8	-0.1	-0.0	0.0	0.0	0.0	0.2	-0.3	0.4	0.6
Patch foraging total patch changes 12 sec	0.7	1.0	1.5	0.9	0.1	0.9	1.0	1.1	1.2	1.1	1.1	-1.0	1.1	0.9
Patch foraging total patch changes 18 sec	0.3	0.7	4.0	-1.8	2.0	0.2	0.3	0.3	0.4	0.3	0.4	-0.3	0.5	0.4
Patch foraging total patch changes 24 sec	0.4	1.3	1.9	-0.4	0.2	1.2	1.4	1.2	1.1	1.1	1.2	-1.3	1.3	1.3
Patch foraging total patch changes 6 sec	1.6	2.7	3.4	1.0	0.5	1.6	1.8	1.8	1.8	1.9	1.8	-1.9	1.8	1.8
Patch foraging time to switch 0 sec	0.2	0.7	1.2	1.1	0.1	1.1	0.9	0.9	0.7	0.8	0.9	-0.8	0.8	0.8
Patch foraging water rate 0 sec	0.7	2.6	4.3	-2.1	0.9	-1.8	-1.6	-1.6	-1.6	-1.6	-1.5	1.7	-1.6	-1.5
Patch foraging water rate 12 sec	0.1	0.2	1.1	-1.1	1.0	0.3	0.3	0.1	0.0	0.1	0.3	-0.2	0.2	0.4
Patch foraging water rate 18 sec	0.0	0.0	0.2	-0.5	-0.1	0.0	0.0	-0.1	-0.2	-0.1	0.0	-0.2	0.1	0.1
Patch foraging water rate 24 sec	0.5	0.8	4.7	-2.2	1.9	-0.2	-0.1	-0.0	0.1	0.1	0.1	0.0	0.1	0.4
Patch foraging water rate 6 sec	0.2	0.3	0.7	0.2	-0.8	-0.5	-0.5	-0.5	-0.6	-0.5	-0.6	0.6	-0.5	-0.6
Seeking ratio, delayed vs. immediate footshock	0.6	0.8	4.2	1.6	-2.0	0.4	0.4	0.6	0.6	0.4	0.5	-0.5	0.5	0.5
Distance traveled before self-admin	0.4	0.8	7.6	0.8	2.8	0.5	0.4	0.4	0.3	0.5	0.3	0.1	0.1	0.0
Distance traveled after self-admin	2.9	5.1	6.5	0.8	1.4	2.5	2.5	2.4	2.5	2.5	2.5	-2.5	2.4	2.2
Extensor digitorum longus weight	0.3	1.3	1.6	-0.5	0.8	1.2	1.2	1.2	1.3	1.2	1.2	-1.3	1.1	1.3
Bone: elastic displacement	0.7	0.9	2.3	1.5	-1.0	1.0	0.9	0.9	0.9	0.9	0.8	-0.9	0.8	0.7
Bone: elastic work	0.0	0.0	0.1	-0.2	0.3	-0.2	-0.1	-0.1	-0.1	-0.1	-0.1	0.1	-0.2	-0.2
Bone: endosteal estimation	0.4	1.0	1.5	-0.4	-0.6	-1.1	-1.2	-1.1	-1.0	-1.0	-1.1	0.9	-1.0	-1.2
Bone: endosteal perimeter	1.1	2.7	3.6	-1.1	-1.1	-1.8	-1.9	-1.8	-1.7	-1.7	-1.7	1.5	-1.7	-1.7
Epididymis fat weight	0.1	0.4	1.1	1.1	-1.0	-0.4	-0.3	-0.5	-0.4	-0.6	-0.5	0.4	-0.4	-0.5
Delta time in closed arm before/after self-admin	0.1	0.1	0.2	0.4	-0.4	0.4	0.5	0.2	0.1	0.1	0.1	0.1	0.1	-0.1
Delta time in open arm before/after self-admin	0.5	0.6	1.2	0.5	0.2	-1.1	-1.1	-0.9	-0.8	-0.8	-0.8	0.6	-0.8	-0.6
Diff in mean of infusions in LGA sessions	0.1	0.1	0.2	-0.5	0.5	0.1	0.3	0.2	0.3	0.1	0.3	-0.2	0.3	0.4
Delay discount exponential model param	2.0	2.7	3.6	0.7	-1.1	-1.6	-1.6	-1.8	-1.7	-1.9	-1.8	1.8	-1.8	-1.8
Extinction: sum of active levers before priming	3.9	6.0	30.7	-5.5	4.6	-1.3	-1.5	-1.5	-1.1	-1.4	-1.1	1.4	-1.1	-0.6
Active lever presses in extinction session 6	1.1	1.1	6.8	-2.0	2.6	0.3	-0.1	0.0	-0.0	0.1	0.3	-0.2	0.3	0.6
Bone: final force	0.3	0.6	3.2	-1.5	1.8	0.1	0.2	0.3	0.3	0.4	0.4	-0.3	0.2	0.3
Bone: final moment	0.3	0.4	2.4	-1.2	1.6	0.1	0.3	0.3	0.4	0.4	0.4	-0.3	0.2	0.3
Food consumed during 24 hour testing period	0.2	0.4	1.6	-1.3	1.3	0.4	0.4	0.3	0.3	0.3	0.5	-0.5	0.4	0.5
Glucose	0.1	0.1	1.0	0.3	-1.0	-0.1	-0.2	-0.1	-0.2	-0.1	-0.1	-0.0	-0.0	-0.1
Heart weight	2.1	3.4	5.4	0.0	-0.5	2.1	2.0	1.9	2.0	1.8	1.9	-2.3	2.1	2.1
Delay discount hyperbolic model param	2.3	2.9	4.0	0.5	-0.9	-1.7	-1.8	-1.8	-1.8	-2.0	-1.9	1.9	-1.9	-1.9
Intermittent access intake day 1-15 change	0.4	2.4	11.5	-3.4	2.4	-1.3	-1.2	-1.2	-1.1	-1.1	-0.9	0.9	-0.7	-0.6
Intermittent access intake escalation	0.5	2.9	13.5	-3.7	3.0	-1.3	-1.2	-1.2	-1.1	-1.1	-0.9	0.9	-0.7	-0.6
Intermittent access intake escalation 2	0.3	0.6	3.0	-1.5	1.7	0.0	0.2	0.2	0.1	0.1	0.3	-0.4	0.5	0.5
Intermitt. access day 1 inactive lever presses	0.3	3.9	18.8	-4.3	3.7	0.8	0.6	0.6	0.9	1.0	1.1	-1.1	1.3	1.5
Intermitt. access day 15 inactive lever presses	0.4	2.0	11.4	-3.4	2.8	-0.7	-0.8	-0.7	-0.5	-0.4	-0.4	0.5	-0.4	-0.1
Intermitt. access escalation Index	1.3	4.1	17.3	4.2	-3.3	1.5	1.5	1.6	1.5	1.5	1.2	-1.2	1.3	1.0
Intermittent access day 1 total infusions	0.9	2.6	3.4	-0.8	-0.8	-1.9	-1.8	-1.8	-1.8	-1.8	-1.8	1.6	-1.7	-1.5
Intermittent access day 15 total infusions	1.8	4.5	14.5	-3.8	2.4	-2.0	-2.0	-2.0	-2.0	-2.0	-1.7	1.7	-1.5	-1.2
Intermittent access terminal intake (last 3 days)	2.2	3.9	11.7	-3.4	1.7	-1.9	-1.9	-1.9	-2.0	-2.0	-1.8	1.7	-1.5	-1.2
Intermittent access total infusions	2.3	2.8	7.9	-2.8	0.9	-1.8	-1.7	-1.7	-1.7	-1.7	-1.6	1.4	-1.3	-1.1
Intermittent access day 1 locomotion	0.3	0.6	2.1	-1.4	1.0	-0.7	-0.7	-0.8	-0.7	-0.7	-0.6	0.6	-0.5	-0.3
Intermittent access day 15 total locomotion	0.7	2.9	3.7	-1.6	0.2	-1.9	-1.9	-1.9	-1.8	-1.8	-1.8	1.7	-1.8	-1.7
Intermittent access total locomotion	3.9	4.7	13.0	-3.6	2.2	-2.1	-2.0	-2.1	-2.1	-2.1	-1.9	1.8	-1.8	-1.6
Intermittent access standard deviation	0.5	2.7	7.0	-2.6	1.5	-1.7	-1.7	-1.7	-1.4	-1.5	-1.5	1.4	-1.3	-1.2
Left kidney weight	0.2	1.3	4.7	-2.2	1.8	0.6	0.7	0.7	0.9	0.6	0.9	-1.0	0.9	1.2
Right kidney weight	0.0	0.0	0.0	-0.2	-0.2	-0.1	-0.1	-0.1	0.1	-0.2	-0.1	-0.2	0.1	0.2
Cocaine induced anxiety	0.1	0.2	1.4	1.2	-0.6	-0.1	0.2	0.2	0.1	0.1	0.1	0.0	-0.0	-0.1
Post-drug Anxiety	0.2	0.3	1.1	1.0	-1.1	-0.4	-0.3	-0.2	-0.2	-0.2	-0.2	0.2	-0.3	-0.5
Baseline Anxiety	0.2	0.3	1.6	0.6	-1.3	-0.1	-0.4	-0.4	-0.4	-0.4	-0.4	0.3	-0.4	-0.7
Tail length	0.3	1.8	6.8	-2.4	2.6	0.7	0.9	0.8	1.1	0.9	1.0	-0.8	0.8	1.0
Length with tail	0.4	1.9	11.6	-3.4	2.9	-0.5	-0.4	-0.5	-0.3	-0.4	-0.3	0.5	-0.4	-0.0
Length without tail	0.5	2.6	3.4	-0.7	-0.2	-1.7	-1.8	-1.8	-1.9	-1.8	-1.8	1.8	-1.7	-1.6
Times rat made contact with spout	1.0	1.2	1.6	-0.4	-0.2	-1.2	-1.2	-1.2	-1.2	-1.2	-1.2	1.2	-1.3	-1.1
Lifetime Intake	1.4	1.8	9.0	-3.0	1.1	-1.2	-1.1	-1.2	-1.2	-1.1	-1.0	0.9	-0.8	-0.4
Liver weight, left	0.1	0.2	1.4	-1.2	0.8	-0.0	-0.0	-0.0	0.1	0.1	0.1	-0.2	0.1	0.3
Liver weight, right	1.7	2.9	6.2	-2.5	0.8	-1.9	-1.8	-1.8	-1.7	-1.7	-1.6	1.6	-1.6	-1.3
Locomotor activity	0.2	0.4	0.5	-0.3	-0.6	-0.5	-0.4	-0.6	-0.7	-0.6	-0.7	0.7	-0.7	-0.7
Locomotor testing distance	0.3	0.8	3.9	-2.0	0.9	-0.7	-0.4	-0.6	-0.7	-0.6	-0.7	0.7	-0.7	-0.5
Locomotor testing rearing	0.1	0.3	0.9	-0.9	0.7	-0.4	-0.1	-0.3	-0.3	-0.4	-0.4	0.7	-0.5	-0.5
Locomotion in novel chamber	1.3	1.8	4.5	2.1	-0.3	1.4	1.1	1.3	1.6	1.3	1.2	-1.3	1.2	1.0
Locomotion in novel chamber post-restriction	1.0	3.1	10.3	3.2	-2.2	1.5	1.5	1.5	1.6	1.4	1.3	-1.7	1.4	1.0
Fecal boli incidents, locomotor time 1	0.7	1.8	2.8	0.5	0.3	1.5	1.6	1.7	1.3	1.3	1.6	-1.4	1.4	1.2
Change in fecal boli incidents, locomotor task	1.2	1.3	7.2	-2.6	2.7	-0.2	-0.1	-0.1	0.1	0.1	0.1	-0.1	-0.0	0.4
Time >=10cm from walls, locomotor time 1	0.7	0.8	2.1	0.3	1.5	1.0	0.9	0.9	1.0	0.7	0.8	-0.7	0.8	0.9
Bouts of movement, locomotor time 1	0.1	0.1	0.5	-0.7	0.3	0.3	0.1	0.1	0.1	0.0	0.3	-0.5	-0.0	0.1
Total resting periods, locomotor time 1	0.1	0.1	0.3	-0.5	0.1	-0.1	-0.3	-0.2	-0.3	-0.3	-0.1	-0.1	-0.4	-0.3
Rest time, locomotor task time 1	3.0	4.8	10.9	-3.3	1.0	-2.4	-2.2	-2.2	-2.3	-2.3	-2.0	2.0	-1.9	-1.7
Distance moved, locomotor task time 1	0.3	1.0	8.6	2.9	-0.6	0.5	0.4	0.6	0.5	0.6	0.3	-0.2	0.2	-0.1
Vertical activity count, locomotor time 1	0.0	0.1	0.8	0.9	0.4	0.1	-0.2	-0.0	0.3	0.3	-0.1	0.1	-0.1	-0.3
Time >=10cm from walls, locomotor time 2	0.9	2.5	20.4	-2.6	4.5	-0.0	0.1	-0.2	-0.4	-0.4	0.0	0.3	-0.2	0.3
Bouts of movement, locomotor time 2	0.5	1.5	12.6	-3.6	1.5	-0.6	-0.8	-0.6	-0.1	-0.5	-0.3	0.0	-0.1	0.2
Total resting periods, locomotor time 2	0.4	1.8	13.7	-3.7	1.1	-1.0	-1.1	-0.9	-0.4	-0.8	-0.6	0.3	-0.4	-0.1
Rest time, locomotor task time 2	2.5	4.1	16.0	-4.0	1.2	-2.1	-2.1	-1.7	-1.6	-1.6	-1.6	1.8	-1.8	-1.5
Distance moved, locomotor task time 2	0.8	1.0	1.4	1.0	1.2	1.1	1.1	1.0	0.9	1.1	1.0	-0.9	0.9	0.9
Vertical activity count, locomotor time 2	0.2	0.5	3.5	-0.4	1.9	0.5	0.3	0.3	0.4	0.5	0.4	-0.3	0.4	0.4
Light reinforcement 1	0.9	4.1	5.7	-2.4	1.8	-1.9	-2.1	-2.0	-2.1	-2.0	-2.0	2.1	-2.1	-1.8
Light reinforcement 2	0.8	1.8	2.5	1.1	-1.0	-1.0	-1.2	-1.4	-1.5	-1.4	-1.5	1.5	-1.5	-1.6
Bone: marrow area	0.3	0.8	1.2	-0.4	-0.5	-1.0	-1.1	-1.0	-0.9	-0.9	-1.0	0.8	-0.9	-1.1
Bone: maximum diameter	0.8	1.6	2.0	-1.1	0.0	-1.4	-1.4	-1.4	-1.3	-1.3	-1.3	1.2	-1.4	-1.4
Bone: maximum force	0.5	0.9	5.5	-2.3	1.9	-0.5	-0.3	-0.3	-0.3	-0.3	-0.2	0.3	-0.4	-0.1
Bone: maximum moment	0.3	0.7	4.1	-2.0	1.6	-0.5	-0.3	-0.3	-0.2	-0.2	-0.2	0.2	-0.3	-0.2
Mean time between licks in bursts	0.1	0.3	1.0	0.4	-1.0	-0.5	-0.5	-0.5	-0.4	-0.4	-0.5	0.4	-0.5	-0.7
Mean num. licks in bursts	0.1	0.4	1.8	1.3	-1.2	0.3	0.3	0.3	0.2	0.2	0.3	-0.4	0.2	0.1
Cd content in liver	2.2	2.4	4.3	-1.9	2.1	1.4	1.4	1.3	1.3	1.3	1.5	-1.6	1.5	1.7
Co content in liver	4.2	4.9	6.2	0.9	1.8	2.5	2.4	2.5	2.4	2.4	2.5	-2.2	2.2	2.1
Cu content in liver	0.1	0.1	0.2	0.0	0.3	0.3	0.4	0.4	0.4	0.4	0.4	-0.2	0.3	0.3
Fe content in liver	0.5	0.6	0.8	-0.7	0.8	-0.8	-0.7	-0.7	-0.9	-0.8	-0.8	0.9	-0.7	-0.5
K content in liver	0.3	0.3	0.8	-0.0	0.9	0.4	0.6	0.6	0.5	0.6	0.5	-0.3	0.5	0.5
Mg content in liver	1.2	1.3	1.7	0.6	0.2	1.2	1.3	1.3	1.3	1.3	1.3	-1.2	1.3	1.1
Mn content in liver	0.2	0.3	0.9	1.0	-0.8	0.4	0.5	0.5	0.4	0.4	0.4	-0.4	0.4	0.2
Na content in liver	1.5	1.6	5.9	-2.4	0.7	-1.3	-1.1	-1.2	-1.2	-1.2	-1.2	1.1	-1.0	-0.8
Rb content in liver	3.6	4.2	5.1	0.4	1.6	2.3	2.2	2.2	2.3	2.3	2.3	-2.1	2.1	2.1
Se content in liver	1.0	1.2	1.9	-0.3	0.9	-1.1	-1.0	-1.1	-1.0	-1.0	-1.1	1.4	-1.2	-1.3
Sr content in liver	0.6	0.5	0.8	0.4	-0.9	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	0.7	-0.7	-0.8
Zn content in liver	1.0	1.2	1.6	-0.3	0.2	1.2	1.2	1.2	1.2	1.1	1.2	-1.3	1.2	1.2
Bone: minimum diameter	0.0	0.1	0.3	-0.4	-0.5	-0.2	-0.2	-0.1	-0.0	-0.0	-0.1	-0.1	-0.2	-0.1
Time in familiar zone, hab. session 1	0.2	0.2	1.1	-1.1	0.8	-0.2	-0.2	-0.2	-0.1	-0.2	-0.1	0.2	-0.1	0.1
Time in novel zone, hab. session 1	0.2	0.2	0.4	0.1	-0.3	-0.5	-0.5	-0.5	-0.6	-0.5	-0.5	0.4	-0.6	-0.6
Total zone transitions, hab. session 1	1.1	1.5	1.9	0.7	0.3	1.4	1.4	1.4	1.4	1.3	1.3	-1.3	1.4	1.3
Total locomotion distance, hab. session 1	0.8	1.1	1.7	-0.7	0.8	1.0	1.0	1.0	1.1	1.0	1.1	-1.2	1.2	1.3
Locomotion velocity, hab. session 1	1.1	1.5	2.3	-0.3	0.6	1.3	1.3	1.3	1.3	1.3	1.3	-1.4	1.5	1.5
Time in familiar zone, hab. session 2	1.3	1.5	2.0	1.4	0.5	1.4	1.4	1.4	1.2	1.3	1.3	-1.1	1.3	1.1
Time in novel zone, hab. session 2	0.5	0.5	0.7	-0.8	-0.4	-0.8	-0.8	-0.8	-0.7	-0.7	-0.7	0.6	-0.7	-0.6
Total zone transitions, hab. session 2	1.4	1.8	2.3	1.4	-0.3	1.5	1.5	1.5	1.3	1.4	1.4	-1.4	1.5	1.2
Total locomotion distance, hab. session 2	0.4	0.5	0.8	0.2	-0.1	0.8	0.8	0.8	0.8	0.8	0.8	-0.9	0.9	0.8
Locomotion velocity, hab. session 2	0.3	0.5	0.8	0.2	-0.3	0.7	0.7	0.7	0.7	0.7	0.7	-0.8	0.9	0.8
Novel to familiar place preference ratio	0.1	0.2	0.8	-0.0	-0.9	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	0.3	-0.3	-0.2
Novelty place preference	0.1	0.2	0.8	0.0	-0.9	-0.4	-0.4	-0.4	-0.4	-0.4	-0.4	0.3	-0.3	-0.2
Time in novel zone, NPP test	0.1	0.1	0.8	0.2	-0.9	-0.0	-0.0	-0.0	-0.0	0.0	-0.0	-0.1	0.1	0.1
Total zone transitions, NPP test	1.3	2.0	2.5	0.3	0.9	1.6	1.6	1.5	1.4	1.5	1.5	-1.4	1.5	1.6
Total locomotion distance, NPP test	0.1	0.1	0.1	0.3	-0.2	0.2	0.3	0.3	0.3	0.3	0.2	-0.2	0.3	0.3
Locomotion velocity, NPP test	0.0	0.0	0.1	0.4	-0.3	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	0.2	-0.1	-0.1
Intraocular pressure	0.1	0.1	0.9	0.6	-0.9	0.1	0.2	0.2	-0.1	0.2	0.1	-0.1	0.1	0.1
Delta distance traveled before/after self-admin	4.4	4.8	7.8	0.7	-2.1	2.1	2.0	2.1	2.3	2.1	2.2	-2.8	2.6	2.4
Delta ambulatory time before/after self-admin	2.7	4.6	7.6	0.8	-2.4	2.0	1.9	2.0	2.2	1.9	2.1	-2.8	2.5	2.3
Parametrial fat weight	0.8	1.9	9.3	-3.1	1.5	-1.5	-1.4	-1.1	-0.8	-0.9	-0.9	0.8	-0.8	-0.5
Pavlov. Cond. lever latency	0.0	0.1	0.3	-0.6	-0.0	-0.2	-0.2	-0.2	-0.2	-0.3	-0.2	0.1	-0.1	-0.1
Pavlov. Cond. magazine entry latency	0.1	0.1	0.2	0.4	-0.0	0.3	0.3	0.4	0.3	0.4	0.3	-0.4	0.4	0.4
Pavlov. Cond. change in total contacts	0.1	0.2	1.6	1.2	-0.3	0.1	0.1	0.1	0.1	0.2	0.1	0.1	0.0	-0.1
Pavlov. Cond. index score	0.1	0.1	0.6	0.8	-0.0	0.2	0.1	0.2	0.1	0.2	0.1	-0.1	0.1	0.1
Pavlov. Cond. latency score	0.0	0.1	0.4	0.6	0.2	0.2	0.2	0.2	0.2	0.3	0.2	-0.1	0.1	0.1
Pavlov. Cond. lever contacts	0.0	0.0	0.5	0.7	-0.2	0.0	0.0	0.1	0.1	0.1	0.0	0.1	-0.0	0.0
Pavlov. Cond. magazine entry number	0.1	0.2	1.3	-1.1	0.5	0.1	0.1	0.0	0.1	0.0	0.1	-0.2	0.1	0.2
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.5	-0.4	0.7	0.6	0.6	0.5	0.6	0.6	0.6	-0.4	0.4	0.5
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.6	0.8	0.1	0.4	0.4	0.4	0.3	0.4	0.3	-0.3	0.3	0.3
Pavlov. Cond. response bias	0.2	0.2	1.5	1.2	-0.7	0.1	0.0	0.1	0.1	0.1	0.0	0.0	0.1	0.0
Pavlov. Cond. lever latency	0.6	0.8	1.3	-0.7	1.2	0.7	0.9	0.9	0.9	0.9	0.9	-0.9	0.9	1.0
Pavlov. Cond. magazine entry latency	3.1	4.3	5.1	0.3	-1.8	-2.2	-2.2	-2.2	-2.2	-2.2	-2.3	2.2	-2.2	-2.2
Pavlov. Cond. change in total contacts	0.3	0.8	1.2	0.6	-1.1	-0.7	-0.9	-0.9	-0.9	-0.9	-0.9	0.9	-1.0	-1.1
Pavlov. Cond. index score	1.6	2.5	3.4	0.8	-1.9	-1.5	-1.6	-1.6	-1.6	-1.7	-1.7	1.6	-1.6	-1.7
Pavlov. Cond. latency score	1.5	2.3	2.8	0.7	-1.7	-1.5	-1.6	-1.6	-1.6	-1.6	-1.6	1.5	-1.6	-1.7
Pavlov. Cond. lever contacts	1.0	1.5	2.2	0.8	-1.5	-1.0	-1.2	-1.2	-1.2	-1.2	-1.2	1.2	-1.2	-1.3
Pavlov. Cond. magazine entry number	2.5	3.2	4.0	-0.8	2.0	1.8	1.8	1.8	1.9	1.9	1.9	-1.8	1.9	1.9
Pavlov. Cond. intertrial magazine entries	0.2	0.4	1.1	-0.6	1.0	0.5	0.5	0.5	0.6	0.6	0.6	-0.5	0.6	0.6
Pavlov. Cond. lever-magazine prob. diff.	1.6	2.4	3.4	0.8	-1.9	-1.5	-1.6	-1.6	-1.6	-1.6	-1.6	1.5	-1.6	-1.7
Pavlov. Cond. response bias	1.9	2.6	3.6	1.0	-1.9	-1.5	-1.6	-1.6	-1.6	-1.7	-1.7	1.6	-1.6	-1.7
Time in closed arm before self-admin	0.9	1.5	8.9	3.0	-2.7	0.1	0.2	0.3	0.2	0.1	-0.1	-0.0	-0.3	-0.3
Time in closed arm after self-admin	2.0	2.3	4.7	2.2	-1.7	1.6	1.7	1.6	1.3	1.4	1.3	-1.2	1.1	1.0
Time in open arm before self-admin	0.5	0.6	0.9	-0.8	1.0	0.8	0.8	0.7	0.9	0.6	0.8	-0.5	0.9	0.7
Time in open arm after self-admin	0.9	0.9	1.4	-0.9	1.2	-1.1	-1.1	-1.1	-0.9	-1.0	-0.9	0.8	-0.7	-0.8
Bone: periosteal estimation	0.3	0.8	1.1	-0.5	-0.5	-1.0	-1.0	-1.0	-0.9	-0.9	-0.9	0.8	-1.0	-1.1
Bone: periosteal perimeter	0.6	1.1	1.6	-0.6	-0.5	-1.2	-1.2	-1.2	-1.1	-1.1	-1.1	1.0	-1.3	-1.2
Bone: post-yield work	0.2	0.3	0.8	-0.9	0.3	-0.5	-0.4	-0.4	-0.5	-0.5	-0.4	0.5	-0.5	-0.4
Progressive ratio test 1 active lever presses	1.1	2.0	5.3	0.5	-2.3	-1.5	-1.5	-1.4	-1.3	-1.3	-1.5	1.2	-1.3	-1.2
Progressive ratio test 1 breakpoint	1.1	1.9	5.2	0.6	-2.3	-1.5	-1.4	-1.4	-1.3	-1.2	-1.4	1.2	-1.2	-1.1
Progressive ratio test 1 inactive lever presses	0.9	2.4	3.5	-1.9	-1.1	-1.7	-1.8	-1.7	-1.4	-1.4	-1.6	1.5	-1.4	-1.4
Progressive ratio test 2 active lever presses	2.1	3.0	4.5	-2.1	0.7	-2.0	-2.0	-1.9	-1.8	-1.8	-1.8	1.6	-1.5	-1.3
Progressive ratio test 2 breakpoint	2.4	3.0	4.9	-2.2	0.8	-2.0	-2.0	-1.9	-1.8	-1.8	-1.8	1.6	-1.5	-1.3
Progressive ratio test 2 inactive lever presses	0.2	0.8	3.0	-1.7	1.3	-0.8	-0.7	-0.8	-0.7	-0.8	-0.7	0.5	-0.5	-0.3
Incentive Sensitization - Responses	1.9	5.2	10.5	-3.2	2.8	-2.2	-2.2	-2.2	-2.2	-2.2	-2.0	2.1	-1.9	-1.7
Incentive Sensitization - Breakpoint	2.5	5.6	11.1	-3.3	2.7	-2.4	-2.3	-2.3	-2.3	-2.3	-2.1	2.2	-2.0	-1.8
Sum of active levers in priming session hrs 5-6	6.7	6.3	39.8	-6.3	4.5	-1.1	-1.4	-1.3	-1.1	-1.1	-0.7	0.7	-0.5	0.0
Progressive ratio	0.4	1.2	9.6	-1.5	3.1	0.3	-0.3	0.3	0.2	0.4	0.4	0.0	0.3	0.5
Food seeking constrained by brief footshock	0.3	0.4	0.8	0.5	-0.6	0.7	0.5	0.4	0.6	0.4	0.4	-0.8	0.6	0.9
Seeking ratio, punishment vs. effort	0.5	1.1	8.4	1.8	-2.9	-0.2	0.3	-0.1	-0.3	-0.2	-0.3	0.0	-0.3	-0.3
Retroperitoneal fat weight	1.4	6.4	8.7	-2.2	0.8	-3.0	-2.7	-2.8	-2.5	-2.8	-2.7	2.6	-2.6	-2.5
Reaction time number correct	0.2	0.6	2.7	1.6	-0.3	0.8	0.7	0.7	0.5	0.5	0.7	-0.6	0.5	0.5
Reaction time mean minus median	0.1	0.3	1.1	0.1	-1.1	-0.7	-0.6	-0.6	-0.5	-0.6	-0.6	0.5	-0.3	-0.4
Reaction time mean minus median AUC	0.1	0.7	4.1	2.0	-1.9	0.1	0.1	0.2	0.1	0.2	-0.0	0.0	0.1	-0.1
Reaction time num false alarms	0.1	0.1	0.3	-0.5	0.6	0.2	0.2	0.1	0.1	0.1	0.1	-0.2	0.3	0.4
Reaction time num false alarms AUC	0.1	0.1	0.3	-0.5	0.6	0.3	0.3	0.3	0.3	0.3	0.3	-0.3	0.4	0.5
Reaction time trials correct on left	0.2	0.6	2.7	1.6	-0.3	0.8	0.7	0.7	0.5	0.5	0.7	-0.6	0.5	0.5
Reaction time trials on left	0.2	0.5	2.8	1.7	-0.4	0.7	0.7	0.6	0.5	0.5	0.6	-0.5	0.5	0.5
Reaction time mean	2.2	4.8	6.2	1.2	-2.2	-2.0	-2.2	-2.2	-2.3	-2.3	-2.4	2.3	-2.3	-2.5
Reaction time mean AUC	1.9	4.7	6.7	2.0	-2.6	-1.9	-2.0	-2.0	-2.2	-2.1	-2.2	2.1	-2.2	-2.4
Median of all reaction times	4.0	6.3	8.8	1.4	-2.2	-2.3	-2.4	-2.5	-2.7	-2.6	-2.7	2.7	-2.8	-3.0
Reaction time omissions	1.1	1.7	2.7	0.1	-0.6	-1.3	-1.4	-1.4	-1.6	-1.5	-1.5	1.5	-1.4	-1.4
Reaction time false alarm rate	0.3	0.4	2.7	-1.6	0.8	-0.5	-0.4	-0.5	-0.4	-0.4	-0.4	0.4	-0.2	-0.1
Reaction time premature initiation rate	1.1	1.7	10.5	-3.2	2.6	-0.0	0.1	0.1	0.3	0.1	0.3	-0.0	0.5	0.6
Reaction time premature initiations	0.3	0.9	4.2	-2.0	2.0	0.3	0.4	0.4	0.5	0.4	0.5	-0.3	0.6	0.7
Std. dev. reaction times	0.2	0.7	2.5	0.7	-1.6	-0.7	-0.7	-0.7	-0.8	-0.8	-0.9	0.8	-0.6	-0.7
Reaction time trials completed	0.2	0.5	2.8	1.7	-0.4	0.7	0.7	0.6	0.5	0.5	0.6	-0.5	0.5	0.5
Reaction time trials AUC	0.2	0.6	3.0	1.7	-0.2	0.8	0.7	0.7	0.5	0.5	0.6	-0.5	0.5	0.5
Run reversals in cocaine runway, females	0.6	0.7	1.4	-0.9	1.2	0.6	0.5	0.8	0.7	0.9	0.8	-0.6	0.8	1.0
Run reversals in cocaine runway, males	1.8	2.0	3.0	1.5	-1.6	-1.4	-1.2	-1.1	-1.5	-1.1	-1.3	1.6	-1.5	-1.7
Latency to leave start box in cocaine runway	2.6	3.5	4.9	-0.9	0.8	-2.0	-2.0	-1.9	-2.0	-1.9	-1.9	2.2	-2.1	-2.1
Latency to leave start box in cocaine runway, F	2.6	3.2	5.1	-2.3	0.9	-2.1	-1.8	-1.9	-1.7	-1.8	-1.8	1.8	-1.8	-1.7
Latency to leave start box in cocaine runway, M	1.8	1.7	3.6	1.9	-0.5	-1.0	-1.3	-1.0	-1.4	-1.0	-1.1	1.6	-1.5	-1.7
Std. dev. time between licks in bursts	0.9	1.8	2.7	0.8	-0.4	1.4	1.4	1.4	1.4	1.4	1.4	-1.6	1.5	1.3
Total sessions with >9 infusions	0.9	1.1	9.8	-3.1	0.7	-0.7	-0.7	-0.7	-0.4	-0.4	-0.4	0.3	-0.3	0.1
Short access day 1 total inactive lever presses	0.5	0.9	6.4	-2.5	1.8	0.3	0.3	0.1	0.1	0.1	0.3	0.0	0.2	0.3
Short access day 10 total inactive lever presses	0.0	0.2	0.8	-0.9	0.8	0.3	0.1	0.2	0.3	0.2	0.2	-0.1	0.3	0.3
Short access day 1 total infusions	0.5	0.9	7.0	-2.6	1.7	0.1	0.2	0.0	0.0	0.1	0.2	-0.0	0.2	0.6
Short access day 10 total infusions	0.7	1.2	2.7	-1.6	0.0	-1.1	-1.1	-1.2	-1.1	-1.0	-1.1	1.0	-1.0	-0.8
Short access total infusions	0.3	0.4	3.6	-1.9	0.6	-0.3	-0.2	-0.3	-0.3	-0.3	-0.3	0.2	-0.2	0.2
Short access day 1 locomotion	1.0	1.7	11.4	-3.4	2.5	-0.3	-0.3	-0.5	-0.4	-0.4	-0.2	0.2	-0.2	0.1
Short access day 10 total locomotion	0.6	2.4	8.7	-3.0	1.9	-1.4	-1.5	-1.4	-1.3	-1.2	-1.2	1.1	-1.1	-0.9
Short access total locomotion	1.1	1.6	8.8	-3.0	1.8	-0.9	-0.9	-1.0	-0.8	-0.8	-0.8	0.7	-0.7	-0.4
One hour access (0.3 mA shock)	0.4	0.5	1.9	1.4	-1.3	-0.4	-0.4	-0.4	-0.5	-0.5	-0.6	0.4	-0.4	-0.6
Compulsive drug intake	1.1	1.7	2.5	1.6	-0.8	1.5	1.4	1.4	1.4	1.4	1.3	-1.2	1.2	1.0
One hour access (shock baseline)	0.5	1.4	2.0	-1.4	0.7	-1.3	-1.2	-1.2	-1.3	-1.3	-1.2	1.1	-1.1	-1.0
Social response proportion	0.1	0.2	0.7	0.8	0.0	0.3	0.4	0.5	0.3	0.5	0.4	-0.3	0.2	0.2
Social responses	0.6	0.7	1.0	0.0	-0.5	-0.9	-0.8	-0.8	-1.0	-0.8	-0.9	1.0	-1.0	-1.0
Social time	0.2	0.3	0.5	0.0	0.5	-0.6	-0.6	-0.4	-0.7	-0.5	-0.5	0.7	-0.6	-0.5
Soleus weight	1.5	4.3	5.8	-1.1	-0.0	-2.3	-2.4	-2.3	-2.3	-2.2	-2.3	2.1	-2.3	-2.2
Bone: stiffness	0.3	0.5	2.2	-1.5	1.0	-0.7	-0.6	-0.6	-0.5	-0.5	-0.5	0.5	-0.6	-0.4
Tibialis anterior weight	0.4	1.5	2.2	0.4	0.2	1.3	1.2	1.3	1.4	1.4	1.3	-1.5	1.3	1.3
Time to tail flick, vehicle, before self-admin	2.0	2.4	16.1	-4.0	3.0	0.3	0.2	0.1	0.1	0.2	0.5	-0.6	0.4	0.9
Time to tail flick, vehicle, after self-admin	0.7	1.5	12.8	-1.3	3.6	-0.2	-0.0	0.0	-0.3	-0.0	-0.1	1.0	-0.8	-0.2
Time to tail flick, test, before self-admin	1.7	1.9	2.5	-0.8	-1.2	-1.5	-1.3	-1.4	-1.4	-1.6	-1.4	1.4	-1.5	-1.4
Time to tail flick, test, after self-admin	0.2	0.2	0.9	1.0	-0.7	0.1	0.4	0.3	0.1	0.2	0.0	0.4	-0.3	-0.1
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	1.0	0.6	0.9	-0.1	-0.0	-0.1	-0.3	-0.1	-0.3	1.0	-0.7	-0.6
Delta time to tail flick, test, before/after SA	1.9	2.3	3.3	1.4	0.2	1.7	1.8	1.7	1.6	1.8	1.6	-1.3	1.5	1.5
Tibia length	0.3	0.9	5.8	2.4	-2.0	0.1	0.1	0.1	0.1	0.1	-0.0	-0.1	-0.1	-0.2
Ambulatory time before self-admin	0.7	2.0	15.1	0.5	3.9	1.1	1.0	1.0	0.9	1.1	0.9	-0.3	0.6	0.6
Ambulatory time after self-admin	2.6	4.2	5.3	1.2	1.2	2.3	2.2	2.2	2.2	2.2	2.2	-2.3	2.2	1.9
Bone: tissue strength	0.4	0.5	2.1	-1.4	0.8	-0.6	-0.5	-0.5	-0.5	-0.5	-0.5	0.5	-0.5	-0.3
Total heroin consumption	1.4	1.7	8.6	-1.3	2.9	-0.9	-0.9	-1.0	-1.1	-1.1	-0.8	1.0	-0.8	-0.7
Bone: trabecular number	0.8	1.5	4.2	-2.1	0.5	-1.4	-1.4	-1.3	-1.1	-1.2	-1.2	1.1	-1.0	-0.6
Bone: trabecular spacing	0.7	1.0	1.4	0.9	0.1	1.2	1.1	1.1	1.1	1.1	1.1	-1.0	0.9	0.7
Bone: trabecular thickness	0.4	0.5	0.8	-0.5	-0.5	-0.9	-0.9	-0.8	-0.7	-0.7	-0.8	0.6	-0.7	-0.6
Bone: trabecular tissue density	0.5	0.9	3.7	1.9	-1.8	-0.4	-0.5	-0.5	-0.6	-0.6	-0.7	0.6	-0.6	-0.9
Water consumed over 24 hours	0.2	0.4	1.2	-1.1	1.0	-0.5	-0.5	-0.5	-0.6	-0.6	-0.5	0.6	-0.6	-0.5
Number of responses in last shaping day	0.4	0.5	2.7	0.2	-1.7	-0.6	-0.8	-0.6	-0.5	-0.4	-0.6	0.7	-0.6	-0.5