Hub : Genes

Slc40a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Slc40a1 0.1 0.07 4.7e-06 0.05 0.06 0.07 0.06 1.3e-04 1.8e-05 2.0e-06 6.4e-06
2 Adipose mRNA stability Slc40a1 0.03 0.02 2.0e-03 0 0 0 -0 3.1e-01 2.3e-01 1.5e-01 5.7e-01
3 Brain gene expression Slc40a1 0.03 0.02 9.0e-03 0.01 0.02 0.02 0.02 2.1e-02 6.7e-03 4.5e-03 1.2e-02
4 Liver gene expression Slc40a1 0.19 0.1 0.0e+00 0.1 0.1 0.1 0.1 3.1e-11 3.0e-11 5.2e-11 1.7e-11
5 Liver mRNA stability Slc40a1 0.09 0.06 7.7e-10 0.04 0.04 0.03 0.03 3.4e-05 1.7e-05 1.3e-04 9.3e-05
6 PL mRNA stability Slc40a1 0.02 0.02 5.0e-03 0.01 0.01 0 0.01 1.4e-02 1.8e-02 1.4e-01 2.7e-02
7 pVTA gene expression Slc40a1 0.07 0.06 8.8e-05 0.03 0.05 0.04 0.05 1.0e-03 6.3e-05 7.0e-04 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density2.44.45.22.1-2.12.3-2.2-2.02.1-1.9
Area under the delay curve0.10.10.30.3-0.10.30.2-0.1-0.6-0.1
BMI with tail1.65.78.7-3.02.5-2.92.32.1-2.01.5
BMI without tail0.10.30.7-0.7-0.1-0.4-0.5-0.40.7-0.8
Body weight0.00.10.20.1-0.30.3-0.4-0.20.5-0.1
Weight adjusted by age0.41.11.8-1.21.0-0.61.01.0-1.01.3
Bone surface0.00.10.20.3-0.00.4-0.10.1-0.00.3
Bone volume0.71.42.41.4-1.21.6-1.2-1.01.0-0.8
Breakpoint value in progressive ratio session0.91.61.91.3-1.31.2-1.3-1.41.2-1.3
Number of licking bursts0.51.62.50.7-1.30.8-1.3-1.41.4-1.6
Context. condit. distance diff. score0.40.51.50.3-0.6-0.0-0.5-0.90.6-1.2
Locomotion velocity, session 10.10.10.20.5-0.30.3-0.2-0.30.2-0.4
Locomotion distance, session 10.40.50.6-0.70.8-0.60.80.8-0.70.7
Locomotion velocity, session 21.51.82.3-1.51.4-1.31.21.5-1.01.3
Locomotion distance, session 21.52.02.3-1.51.4-1.31.41.5-1.41.5
Locomotion velocity, session 30.10.10.2-0.40.3-0.50.20.2-0.20.1
Locomotion distance, session 30.10.10.2-0.1-0.1-0.4-0.2-0.30.3-0.4
Stereotopy head waving bouts, day 30.50.50.7-0.90.7-0.60.80.7-0.80.7
Stereotopy head waving duration, day 30.00.00.10.0-0.10.20.0-0.0-0.1-0.0
Locomotion velocity, session 71.81.92.7-1.21.3-1.11.41.5-1.51.6
Locomotion distance, session 71.01.31.8-1.11.1-1.01.11.3-1.11.4
Stereotopy head waving bouts, day 70.30.40.50.6-0.60.6-0.7-0.70.6-0.7
Stereotopy head waving duration, day 70.50.60.70.8-0.80.8-0.8-0.80.7-0.7
Locomotion velocity, session 80.00.00.1-0.20.0-0.3-0.1-0.10.1-0.2
Locomotion distance, session 80.30.41.1-0.80.6-1.00.70.4-0.60.2
Degree of sensitization distance0.70.71.6-0.70.7-0.20.81.1-0.91.2
Degree of sensitization stereotypy0.50.50.60.8-0.60.6-0.7-0.80.7-0.8
Conditioned locomotion0.00.00.10.2-0.10.10.1-0.0-0.2-0.0
Cocaine response after cond. corrected0.81.21.8-1.21.1-0.81.01.2-1.01.3
Cocaine response after cond. not corrected0.81.12.3-0.80.9-0.41.11.2-1.01.5
Cocaine response before conditioning0.10.10.30.30.10.20.30.3-0.40.5
Saline control response0.20.20.40.6-0.40.2-0.4-0.50.5-0.6
Bone: connectivity density0.20.30.40.5-0.50.5-0.6-0.50.6-0.4
Bone: cortical apparent density4.26.68.9-2.82.7-3.02.62.5-2.32.1
Bone: cortical area0.61.01.5-1.11.1-0.50.91.1-1.01.2
Bone: cortical porosity1.21.32.51.6-1.11.0-0.9-1.20.8-1.1
Bone: cortical porosity1.11.22.61.6-1.11.3-0.8-1.10.6-0.8
Bone: cortical thickness1.01.72.5-1.61.5-1.31.21.3-1.21.1
Bone: cortical thickness0.30.40.5-0.60.6-0.40.60.7-0.60.7
Bone: cortical tissue density4.06.48.6-2.72.6-2.92.52.4-2.32.1
Condit. Reinf. active minus inactive responses4.04.56.02.4-2.22.4-2.1-2.01.9-1.7
Condit. Reinf. active-inactive response ratio2.62.73.82.0-1.71.8-1.6-1.61.5-1.4
Condit. Reinf. active responses1.92.53.92.0-1.72.0-1.5-1.41.3-1.1
Condit. Reinf. inactive responses0.10.10.2-0.20.20.00.30.4-0.50.5
Incentive salience index mean3.34.35.72.4-2.12.2-2.0-2.01.9-1.8
Condit. Reinf. lever presses1.32.02.41.6-1.51.3-1.3-1.51.2-1.5
Condit. Reinf. active minus inactive responses0.91.32.21.3-1.11.5-1.2-1.01.1-0.6
Condit. Reinf. active-inactive response ratio1.32.02.41.5-1.41.6-1.5-1.41.4-1.1
Condit. Reinf. active responses0.10.10.30.3-0.20.6-0.3-0.10.20.2
Condit. Reinf. inactive responses0.50.81.2-0.90.9-0.60.81.0-0.91.1
Condit. Reinf. lever presses0.00.00.10.1-0.20.3-0.3-0.10.3-0.0
Condit. Reinf. lever reinforcers received0.00.10.20.10.00.4-0.10.10.00.4
Conditioned reinforcement - actives0.00.20.4-0.60.3-0.70.30.3-0.20.3
Conditioned reinforcement - inactives0.10.40.6-0.70.7-0.80.40.5-0.50.6
Conditioned locomotion3.45.06.9-1.92.3-2.62.32.4-1.82.3
Patch foraging indifference point 0 sec0.82.24.9-2.21.5-1.61.21.4-0.91.1
Patch foraging indifference point AUC0.30.71.1-0.60.7-0.50.91.0-0.91.1
Delay disc. indifference point, 0s delay0.10.10.2-0.50.2-0.20.40.1-0.20.2
Delay disc. indifference point, 16s delay0.70.91.71.3-1.01.2-0.7-0.90.4-0.9
Delay disc. indifference point, 2s delay0.10.10.10.10.2-0.30.30.2-0.30.3
Delay disc. indifference point, 24s delay0.20.30.60.7-0.60.4-0.5-0.70.3-0.8
Delay disc. indifference point, 4s delay0.50.51.1-0.50.6-0.51.00.6-1.10.5
Delay disc. indifference point, 8s delay0.10.10.40.4-0.40.6-0.4-0.4-0.2-0.2
Indifference point function ln k0.10.30.7-0.0-0.3-0.0-0.6-0.60.6-0.8
Indifference point function log k0.10.30.7-0.0-0.3-0.0-0.6-0.60.6-0.8
Patch foraging total patch changes 0 sec0.82.45.5-2.31.6-1.71.31.5-1.01.2
Patch foraging total patch changes 12 sec0.40.50.8-0.80.7-0.50.60.9-0.60.8
Patch foraging total patch changes 18 sec0.41.01.3-1.01.0-1.01.11.1-1.00.9
Patch foraging total patch changes 24 sec0.31.11.3-1.01.1-0.91.11.1-1.11.0
Patch foraging total patch changes 6 sec1.52.63.3-1.81.6-1.61.61.7-1.41.4
Patch foraging time to switch 0 sec0.20.91.91.4-1.00.9-0.9-1.00.6-0.8
Patch foraging water rate 0 sec0.20.61.7-1.30.8-0.80.50.8-0.30.6
Patch foraging water rate 12 sec0.00.10.1-0.3-0.0-0.2-0.3-0.20.3-0.4
Patch foraging water rate 18 sec0.30.61.00.3-0.60.4-1.0-0.90.9-1.0
Patch foraging water rate 24 sec0.00.00.1-0.3-0.10.20.00.00.10.0
Patch foraging water rate 6 sec0.10.10.4-0.70.3-0.60.1-0.10.1-0.3
Seeking ratio, delayed vs. immediate footshock0.50.81.11.1-0.90.9-0.8-0.71.1-0.4
Distance traveled before self-admin0.81.72.61.6-1.31.6-1.3-1.11.2-0.8
Distance traveled after self-admin0.40.61.01.0-0.80.9-0.7-0.70.7-0.4
Extensor digitorum longus weight9.638.242.3-5.86.5-5.96.46.2-6.46.0
Bone: elastic displacement1.92.43.21.3-1.51.1-1.7-1.71.7-1.8
Bone: elastic work0.81.01.61.3-1.01.2-1.0-1.00.8-0.8
Bone: endosteal estimation0.20.62.40.9-0.71.5-0.5-0.20.10.3
Bone: endosteal perimeter0.10.31.10.4-0.51.0-0.6-0.30.50.0
Epididymis fat weight0.10.61.7-0.40.7-0.00.60.9-0.91.3
Delta time in closed arm before/after self-admin0.60.50.9-0.90.7-0.80.80.7-0.60.6
Delta time in open arm before/after self-admin1.21.52.21.4-1.21.5-1.3-1.21.0-0.9
Diff in mean of infusions in LGA sessions0.50.81.21.1-1.00.9-0.8-1.00.7-0.8
Delay discount exponential model param0.10.10.3-0.30.0-0.2-0.20.10.50.1
Extinction: sum of active levers before priming1.01.51.91.2-1.21.4-1.2-1.21.2-1.1
Active lever presses in extinction session 60.60.60.80.6-0.70.7-0.8-0.90.8-0.7
Bone: final force0.40.61.4-0.50.70.00.70.9-0.91.2
Bone: final moment0.40.61.2-0.60.7-0.00.70.9-0.91.1
Food consumed during 24 hour testing period0.10.20.5-0.10.3-0.00.40.5-0.40.7
Glucose0.81.32.50.7-1.00.5-1.2-1.21.6-1.4
Heart weight0.10.10.20.5-0.20.3-0.3-0.20.2-0.0
Delay discount hyperbolic model param0.10.10.3-0.2-0.0-0.1-0.30.10.60.1
Intermittent access intake day 1-15 change0.00.10.40.00.1-0.30.10.1-0.6-0.0
Intermittent access intake escalation0.00.10.3-0.10.1-0.40.10.1-0.6-0.1
Intermittent access intake escalation 20.10.20.40.2-0.50.4-0.3-0.5-0.1-0.7
Intermitt. access day 1 inactive lever presses0.00.51.2-1.10.6-1.00.70.4-0.7-0.0
Intermitt. access day 15 inactive lever presses0.10.41.0-0.60.7-1.00.60.4-0.40.3
Intermitt. access escalation Index0.10.40.70.8-0.50.2-0.5-0.60.8-0.8
Intermittent access day 1 total infusions0.41.12.30.7-1.10.4-1.2-1.11.5-1.1
Intermittent access day 15 total infusions0.10.20.50.2-0.4-0.5-0.5-0.40.5-0.7
Intermittent access terminal intake (last 3 days)0.10.10.5-0.4-0.1-0.7-0.2-0.20.1-0.5
Intermittent access total infusions0.30.30.60.2-0.5-0.3-0.7-0.60.8-0.7
Intermittent access day 1 locomotion0.10.20.60.4-0.2-0.8-0.3-0.10.7-0.2
Intermittent access day 15 total locomotion0.20.71.1-0.60.8-1.10.70.9-0.70.8
Intermittent access total locomotion0.30.31.7-0.40.4-1.30.20.40.00.2
Intermittent access standard deviation0.10.40.6-0.40.7-0.80.60.6-0.70.5
Left kidney weight0.10.51.30.2-0.60.5-0.8-0.61.1-0.6
Right kidney weight0.10.71.2-1.10.9-0.80.70.9-0.50.9
Cocaine induced anxiety0.92.34.7-2.21.5-1.71.51.3-1.21.1
Post-drug Anxiety1.61.92.5-1.61.3-1.41.51.4-1.21.2
Baseline Anxiety0.71.12.91.7-1.01.4-0.8-0.70.4-0.6
Tail length2.111.314.23.1-3.53.6-3.8-3.13.7-2.7
Length with tail1.88.112.23.0-3.03.5-3.1-2.42.8-1.7
Length without tail0.10.41.41.0-0.41.2-0.20.1-0.10.6
Times rat made contact with spout1.41.62.51.1-1.20.8-1.2-1.41.4-1.6
Lifetime Intake0.10.10.5-0.40.1-0.7-0.10.00.2-0.1
Liver weight, left0.10.10.40.2-0.40.6-0.30.00.20.2
Liver weight, right0.20.40.70.4-0.60.8-0.8-0.40.7-0.2
Locomotor activity0.10.20.3-0.50.5-0.30.40.3-0.50.4
Locomotor testing distance0.20.60.70.6-0.70.7-0.8-0.80.8-0.8
Locomotor testing rearing0.31.01.60.4-1.00.6-1.1-1.01.2-1.3
Locomotion in novel chamber3.64.95.7-2.12.2-2.02.32.3-2.02.4
Locomotion in novel chamber post-restriction1.95.77.2-2.42.4-1.82.52.4-2.72.4
Fecal boli incidents, locomotor time 10.10.30.60.3-0.60.3-0.6-0.40.8-0.5
Change in fecal boli incidents, locomotor task0.10.10.20.10.1-0.50.1-0.10.3-0.1
Time >=10cm from walls, locomotor time 10.91.11.7-1.31.1-0.81.01.1-0.81.2
Bouts of movement, locomotor time 10.91.11.4-1.01.1-1.21.20.9-1.20.8
Total resting periods, locomotor time 11.61.92.2-1.41.4-1.51.51.3-1.41.2
Rest time, locomotor task time 10.10.10.6-0.4-0.2-0.2-0.2-0.20.8-0.4
Distance moved, locomotor task time 10.10.41.11.0-0.50.7-0.4-0.6-0.0-0.5
Vertical activity count, locomotor time 10.00.20.60.70.10.10.20.1-0.70.1
Time >=10cm from walls, locomotor time 20.41.21.61.2-1.11.1-1.1-1.21.0-1.1
Bouts of movement, locomotor time 21.13.86.0-1.62.0-2.02.11.7-2.41.5
Total resting periods, locomotor time 20.93.65.2-1.72.0-2.02.11.7-2.31.5
Rest time, locomotor task time 20.20.30.7-0.80.4-0.80.10.20.50.0
Distance moved, locomotor task time 20.30.31.11.0-0.50.8-0.3-0.4-0.1-0.3
Vertical activity count, locomotor time 20.10.10.60.40.10.20.4-0.1-0.8-0.1
Light reinforcement 12.09.110.3-2.93.2-3.13.13.1-3.02.8
Light reinforcement 20.71.62.0-1.41.4-1.41.21.2-1.01.1
Bone: marrow area0.20.52.10.8-0.61.5-0.4-0.20.00.3
Bone: maximum diameter0.10.20.4-0.60.4-0.10.20.5-0.30.5
Bone: maximum force0.30.61.7-0.20.50.40.70.9-1.01.3
Bone: maximum moment0.30.61.5-0.30.60.30.70.9-1.01.2
Mean time between licks in bursts0.74.35.0-2.12.2-1.82.02.1-2.12.1
Mean num. licks in bursts0.10.30.5-0.20.6-0.40.70.6-0.70.7
Cd content in liver4.75.26.71.7-2.62.3-2.4-2.22.5-2.2
Co content in liver2.83.34.01.3-1.81.5-2.0-1.92.0-2.0
Cu content in liver1.61.92.21.4-1.41.4-1.4-1.51.2-1.4
Fe content in liver3.64.55.12.2-2.11.9-2.1-2.22.1-2.2
K content in liver3.53.43.8-1.81.9-1.71.91.8-2.01.8
Mg content in liver0.50.50.7-0.70.7-0.70.80.6-0.80.6
Mn content in liver0.30.30.7-0.90.7-0.80.30.3-0.40.2
Na content in liver0.00.00.10.20.2-0.10.10.0-0.30.1
Rb content in liver5.46.37.2-2.42.7-2.32.52.5-2.62.5
Se content in liver0.20.30.4-0.50.6-0.60.40.5-0.50.5
Sr content in liver0.00.00.1-0.40.1-0.20.10.1-0.1-0.0
Zn content in liver0.00.00.0-0.2-0.10.1-0.0-0.00.1-0.0
Bone: minimum diameter0.30.61.3-0.60.70.10.60.9-0.81.2
Time in familiar zone, hab. session 10.10.10.30.1-0.3-0.1-0.4-0.40.5-0.5
Time in novel zone, hab. session 12.93.33.81.8-1.91.9-1.9-1.81.8-1.6
Total zone transitions, hab. session 10.60.91.4-0.50.9-0.61.01.0-1.11.2
Total locomotion distance, hab. session 10.81.12.6-0.60.9-0.31.01.3-1.21.6
Locomotion velocity, hab. session 11.92.74.4-1.21.5-0.91.71.9-1.82.1
Time in familiar zone, hab. session 20.10.20.30.2-0.30.1-0.5-0.40.6-0.5
Time in novel zone, hab. session 20.30.30.40.4-0.60.5-0.5-0.60.5-0.6
Total zone transitions, hab. session 20.00.00.10.2-0.0-0.10.1-0.1-0.2-0.1
Total locomotion distance, hab. session 20.10.10.20.10.10.20.30.3-0.40.5
Locomotion velocity, hab. session 20.20.30.6-0.20.4-0.00.60.6-0.70.8
Novel to familiar place preference ratio1.01.31.91.4-1.11.2-1.2-1.11.1-0.9
Novelty place preference1.21.51.71.3-1.11.2-1.3-1.21.2-1.1
Time in novel zone, NPP test1.61.92.21.5-1.31.4-1.5-1.41.4-1.3
Total zone transitions, NPP test0.30.50.6-0.80.7-0.70.80.6-0.80.6
Total locomotion distance, NPP test0.20.30.5-0.50.4-0.10.50.6-0.50.7
Locomotion velocity, NPP test0.50.81.1-1.00.8-0.50.81.0-0.91.0
Intraocular pressure0.00.10.20.2-0.30.1-0.3-0.30.3-0.4
Delta distance traveled before/after self-admin0.10.10.3-0.60.4-0.40.40.3-0.20.2
Delta ambulatory time before/after self-admin0.30.40.9-1.00.6-0.60.70.6-0.60.5
Parametrial fat weight0.00.10.3-0.30.3-0.50.50.3-0.3-0.0
Pavlov. Cond. lever latency2.73.44.2-1.81.9-1.81.82.0-1.61.9
Pavlov. Cond. magazine entry latency2.83.54.32.0-2.02.1-1.9-1.91.6-1.7
Pavlov. Cond. change in total contacts2.42.63.11.6-1.61.8-1.6-1.71.4-1.5
Pavlov. Cond. index score3.74.75.42.2-2.32.2-2.2-2.31.9-2.2
Pavlov. Cond. latency score3.54.45.12.1-2.22.1-2.1-2.21.8-2.1
Pavlov. Cond. lever contacts2.83.44.11.9-1.91.8-1.7-2.01.5-2.0
Pavlov. Cond. magazine entry number4.25.36.2-2.52.4-2.42.32.4-2.02.1
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.20.2-0.20.10.3-0.20.3
Pavlov. Cond. lever-magazine prob. diff.3.13.94.42.0-2.12.0-1.9-2.11.7-2.0
Pavlov. Cond. response bias3.94.95.62.4-2.32.3-2.2-2.31.9-2.2
Pavlov. Cond. lever latency0.10.10.2-0.30.3-0.40.40.2-0.40.1
Pavlov. Cond. magazine entry latency0.30.40.80.6-0.70.9-0.4-0.50.5-0.4
Pavlov. Cond. change in total contacts0.51.21.61.0-1.11.2-1.1-0.91.3-0.7
Pavlov. Cond. index score0.20.30.80.6-0.60.9-0.5-0.40.6-0.2
Pavlov. Cond. latency score0.10.20.60.5-0.50.8-0.3-0.20.4-0.0
Pavlov. Cond. lever contacts0.40.50.80.7-0.70.8-0.8-0.60.9-0.5
Pavlov. Cond. magazine entry number0.50.61.1-0.90.9-1.10.60.7-0.70.6
Pavlov. Cond. intertrial magazine entries0.30.71.2-0.51.0-1.10.90.7-1.00.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.5-0.40.7-0.3-0.20.3-0.0
Pavlov. Cond. response bias0.40.51.00.7-0.71.0-0.8-0.60.8-0.4
Time in closed arm before self-admin1.42.44.52.1-1.61.9-1.5-1.31.1-1.1
Time in closed arm after self-admin0.20.20.70.6-0.50.8-0.2-0.30.0-0.2
Time in open arm before self-admin1.11.32.8-1.41.2-1.71.01.1-0.40.9
Time in open arm after self-admin0.80.91.51.2-0.90.8-1.1-0.81.1-0.5
Bone: periosteal estimation0.10.20.90.1-0.00.9-0.00.3-0.30.7
Bone: periosteal perimeter0.10.20.70.2-0.40.9-0.6-0.30.4-0.1
Bone: post-yield work0.10.10.40.3-0.10.60.10.2-0.50.4
Progressive ratio test 1 active lever presses0.10.10.7-0.40.3-0.80.10.20.10.1
Progressive ratio test 1 breakpoint0.00.10.4-0.20.2-0.70.10.20.10.1
Progressive ratio test 1 inactive lever presses0.71.83.0-1.71.4-1.71.31.1-1.10.9
Progressive ratio test 2 active lever presses0.00.00.2-0.20.1-0.4-0.1-0.0-0.0-0.1
Progressive ratio test 2 breakpoint0.00.00.2-0.30.1-0.4-0.1-0.10.1-0.2
Progressive ratio test 2 inactive lever presses0.00.10.5-0.20.2-0.7-0.00.10.1-0.0
Incentive Sensitization - Responses0.10.40.60.3-0.60.5-0.8-0.60.7-0.6
Incentive Sensitization - Breakpoint0.10.30.40.3-0.50.4-0.6-0.50.5-0.6
Sum of active levers in priming session hrs 5-61.81.72.81.7-1.31.6-1.1-1.21.0-0.9
Progressive ratio0.31.01.8-1.10.9-0.50.91.1-1.31.1
Food seeking constrained by brief footshock0.50.61.1-1.00.7-0.20.70.9-0.61.0
Seeking ratio, punishment vs. effort0.00.10.2-0.10.3-0.20.20.30.10.4
Retroperitoneal fat weight0.62.63.1-1.61.8-1.51.61.6-1.71.6
Reaction time number correct0.41.42.0-1.31.4-1.41.11.2-1.01.0
Reaction time mean minus median0.32.02.81.7-1.51.6-1.2-1.41.2-1.2
Reaction time mean minus median AUC0.31.82.31.5-1.41.4-1.2-1.31.2-1.2
Reaction time num false alarms2.95.06.8-2.62.2-2.32.22.2-2.12.0
Reaction time num false alarms AUC3.06.88.7-3.02.6-2.62.62.6-2.52.4
Reaction time trials correct on left0.41.42.0-1.31.4-1.41.11.2-1.01.0
Reaction time trials on left0.41.41.9-1.21.3-1.41.01.2-0.91.0
Reaction time mean2.65.89.43.1-2.52.6-2.2-2.51.8-2.0
Reaction time mean AUC2.15.07.82.8-2.42.4-2.1-2.31.7-2.0
Median of all reaction times3.85.99.53.1-2.52.6-2.2-2.51.8-2.1
Reaction time omissions0.91.51.91.3-1.41.0-1.1-1.31.1-1.3
Reaction time false alarm rate2.02.84.0-2.01.6-1.61.71.6-1.71.5
Reaction time premature initiation rate0.10.10.30.5-0.30.4-0.3-0.40.0-0.4
Reaction time premature initiations0.00.10.1-0.10.3-0.30.20.2-0.40.1
Std. dev. reaction times1.65.57.82.8-2.52.6-2.2-2.31.9-1.9
Reaction time trials completed0.41.41.9-1.21.3-1.41.01.2-0.91.0
Reaction time trials AUC0.31.21.7-1.21.2-1.31.01.1-0.90.9
Run reversals in cocaine runway, females0.91.01.8-1.31.0-0.60.91.0-0.91.2
Run reversals in cocaine runway, males1.01.11.5-1.01.1-0.71.21.1-1.11.1
Latency to leave start box in cocaine runway3.34.55.8-2.02.2-2.12.42.1-2.21.8
Latency to leave start box in cocaine runway, F1.41.82.8-1.11.4-1.71.61.3-1.20.9
Latency to leave start box in cocaine runway, M4.24.05.0-2.22.1-1.62.02.0-2.12.0
Std. dev. time between licks in bursts2.54.65.8-2.42.3-2.42.12.0-2.21.6
Total sessions with >9 infusions2.73.34.1-2.01.9-2.01.71.9-1.41.8
Short access day 1 total inactive lever presses1.53.04.1-1.61.8-1.31.92.0-1.51.9
Short access day 10 total inactive lever presses0.00.20.5-0.50.3-0.10.40.3-0.70.3
Short access day 1 total infusions1.83.65.1-2.32.1-1.51.82.0-1.42.0
Short access day 10 total infusions0.10.20.5-0.4-0.1-0.6-0.4-0.40.4-0.7
Short access total infusions0.30.40.8-0.90.6-0.90.50.5-0.30.4
Short access day 1 locomotion2.54.14.7-2.02.2-1.82.12.1-1.82.1
Short access day 10 total locomotion0.10.30.9-0.50.5-1.00.40.6-0.30.4
Short access total locomotion2.03.04.5-1.51.8-2.11.71.8-1.31.7
One hour access (0.3 mA shock)0.20.20.40.4-0.50.3-0.5-0.50.4-0.6
Compulsive drug intake0.81.21.7-1.11.1-0.61.31.1-1.11.1
One hour access (shock baseline)0.30.81.00.8-1.00.4-1.0-0.91.0-1.0
Social response proportion0.30.40.60.8-0.60.6-0.6-0.70.6-0.6
Social responses0.00.00.1-0.30.1-0.00.00.2-0.10.2
Social time1.42.22.61.6-1.51.1-1.4-1.61.4-1.6
Soleus weight1.54.55.2-2.02.2-1.52.32.3-2.32.3
Bone: stiffness0.61.12.6-0.70.80.01.01.2-1.31.6
Tibialis anterior weight4.314.716.8-3.84.1-3.74.03.8-3.93.5
Time to tail flick, vehicle, before self-admin0.10.20.80.9-0.30.1-0.2-0.20.1-0.4
Time to tail flick, vehicle, after self-admin0.51.11.61.3-1.00.9-0.9-1.10.9-1.1
Time to tail flick, test, before self-admin2.62.94.0-1.51.7-1.32.01.8-1.91.7
Time to tail flick, test, after self-admin3.33.54.2-1.61.9-1.62.02.0-2.02.0
Delta time to tail flick, vehicle, before/after SA0.20.20.40.2-0.50.5-0.5-0.60.5-0.6
Delta time to tail flick, test, before/after SA0.10.10.30.5-0.30.2-0.4-0.30.3-0.3
Tibia length0.41.14.21.3-0.92.0-0.7-0.40.40.3
Ambulatory time before self-admin0.72.23.21.8-1.61.8-1.5-1.31.3-1.0
Ambulatory time after self-admin0.30.50.70.6-0.80.8-0.7-0.70.7-0.5
Bone: tissue strength0.00.00.1-0.1-0.20.2-0.3-0.10.2-0.1
Total heroin consumption1.51.82.31.4-1.41.3-1.2-1.50.9-1.5
Bone: trabecular number1.01.92.41.3-1.41.5-1.5-1.31.5-1.1
Bone: trabecular spacing1.11.62.2-1.01.3-1.11.41.2-1.51.3
Bone: trabecular thickness6.28.59.72.6-3.02.9-3.1-2.93.1-2.8
Bone: trabecular tissue density0.00.00.10.10.10.3-0.10.2-0.00.3
Water consumed over 24 hours0.00.00.1-0.0-0.1-0.20.0-0.10.2-0.3
Number of responses in last shaping day0.00.00.30.5-0.0-0.10.0-0.1-0.1-0.1