Hub : Genes

Slc40a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Slc40a1 0.1 0.07 4.7e-06 0.05 0.06 0.07 0.06 1.3e-04 1.8e-05 1.8e-06 6.5e-06
2 Adipose mRNA stability Slc40a1 0.03 0.02 2.0e-03 0 0 0 -0 3.1e-01 2.3e-01 1.5e-01 5.5e-01
3 Brain gene expression Slc40a1 0.03 0.02 9.0e-03 0.01 0.02 0.02 0.02 2.1e-02 6.7e-03 4.5e-03 1.1e-02
4 Liver gene expression Slc40a1 0.19 0.1 0.0e+00 0.1 0.1 0.1 0.1 3.1e-11 3.0e-11 5.2e-11 1.8e-11
5 Liver mRNA stability Slc40a1 0.09 0.06 7.7e-10 0.04 0.04 0.03 0.03 3.4e-05 1.7e-05 1.3e-04 9.9e-05
6 PL mRNA stability Slc40a1 0.02 0.02 5.0e-03 0.01 0.01 0 0.01 1.4e-02 1.8e-02 1.4e-01 2.7e-02
7 pVTA gene expression Slc40a1 0.07 0.06 8.8e-05 0.03 0.05 0.04 0.05 1.0e-03 6.3e-05 7.1e-04 1.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density2.64.45.1-2.12.1-2.3-2.2-2.0-2.1-1.9
Area under the delay curve0.10.10.3-0.30.1-0.20.2-0.10.6-0.1
BMI with tail1.65.68.73.0-2.52.82.32.12.01.5
BMI without tail0.10.30.70.70.10.3-0.5-0.4-0.7-0.8
Body weight0.00.10.2-0.10.3-0.3-0.4-0.2-0.5-0.1
Weight adjusted by age0.71.11.81.2-1.00.71.01.01.01.3
Bone surface0.00.10.1-0.30.0-0.4-0.10.10.00.3
Bone volume0.81.42.2-1.41.2-1.5-1.2-1.0-1.0-0.8
Breakpoint value in progressive ratio session1.41.61.9-1.31.3-1.2-1.3-1.4-1.2-1.3
Number of licking bursts1.01.62.5-0.71.3-0.9-1.4-1.4-1.4-1.6
Context. condit. distance diff. score0.40.51.5-0.30.6-0.1-0.5-0.9-0.6-1.2
Locomotion velocity, session 10.10.10.2-0.50.3-0.3-0.2-0.3-0.2-0.4
Locomotion distance, session 10.40.50.60.7-0.80.60.80.80.70.7
Locomotion velocity, session 21.51.82.31.5-1.41.31.21.51.01.3
Locomotion distance, session 21.52.12.31.5-1.41.31.41.51.41.5
Locomotion velocity, session 30.10.10.20.4-0.30.40.20.20.20.1
Locomotion distance, session 30.10.10.20.10.10.3-0.2-0.3-0.3-0.4
Stereotopy head waving bouts, day 30.50.60.70.9-0.70.60.80.70.80.7
Stereotopy head waving duration, day 30.00.00.0-0.00.1-0.20.0-0.00.1-0.0
Locomotion velocity, session 71.82.02.71.2-1.31.21.41.51.51.6
Locomotion distance, session 71.11.31.81.1-1.11.11.11.31.11.4
Stereotopy head waving bouts, day 70.40.40.5-0.60.6-0.6-0.7-0.7-0.6-0.7
Stereotopy head waving duration, day 70.50.60.7-0.80.8-0.8-0.8-0.8-0.7-0.7
Locomotion velocity, session 80.00.00.10.2-0.00.2-0.1-0.1-0.1-0.2
Locomotion distance, session 80.30.40.90.8-0.60.90.70.40.60.2
Degree of sensitization distance0.70.81.60.7-0.70.40.81.10.91.2
Degree of sensitization stereotypy0.50.50.6-0.80.6-0.6-0.7-0.8-0.7-0.8
Conditioned locomotion0.00.00.1-0.20.1-0.10.1-0.00.2-0.0
Cocaine response after cond. corrected1.01.21.81.2-1.10.81.01.21.01.3
Cocaine response after cond. not corrected1.01.12.30.8-0.90.51.11.21.01.5
Cocaine response before conditioning0.10.10.3-0.3-0.1-0.10.30.30.40.5
Saline control response0.20.20.4-0.60.4-0.3-0.4-0.5-0.5-0.6
Bone: connectivity density0.20.30.4-0.50.5-0.5-0.6-0.5-0.6-0.4
Bone: cortical apparent density4.86.68.62.8-2.72.92.62.52.32.1
Bone: cortical area0.71.11.51.1-1.10.60.91.11.01.2
Bone: cortical porosity1.21.32.5-1.61.1-1.1-0.9-1.2-0.8-1.1
Bone: cortical porosity1.11.22.6-1.61.1-1.2-0.8-1.1-0.6-0.8
Bone: cortical thickness1.01.72.51.6-1.51.31.21.31.21.1
Bone: cortical thickness0.30.40.50.6-0.60.40.60.70.60.7
Bone: cortical tissue density4.76.48.32.7-2.62.92.52.42.32.1
Condit. Reinf. active minus inactive responses4.04.56.0-2.42.2-2.3-2.1-2.0-1.9-1.7
Condit. Reinf. active-inactive response ratio2.62.73.8-2.01.7-1.8-1.6-1.6-1.5-1.4
Condit. Reinf. active responses2.02.53.9-2.01.7-1.9-1.5-1.4-1.3-1.1
Condit. Reinf. inactive responses0.10.10.20.2-0.20.00.30.40.50.5
Incentive salience index mean3.54.35.7-2.42.1-2.2-2.0-2.0-1.9-1.8
Condit. Reinf. lever presses1.42.02.4-1.61.5-1.3-1.3-1.5-1.2-1.5
Condit. Reinf. active minus inactive responses1.01.32.0-1.31.1-1.4-1.2-1.0-1.1-0.6
Condit. Reinf. active-inactive response ratio1.72.02.3-1.51.4-1.5-1.5-1.4-1.4-1.1
Condit. Reinf. active responses0.10.10.2-0.30.2-0.5-0.3-0.1-0.20.2
Condit. Reinf. inactive responses0.60.81.20.9-0.90.60.81.00.91.1
Condit. Reinf. lever presses0.00.00.1-0.10.2-0.3-0.3-0.1-0.3-0.0
Condit. Reinf. lever reinforcers received0.00.00.2-0.1-0.0-0.3-0.10.1-0.00.4
Conditioned reinforcement - actives0.10.20.40.6-0.30.60.30.30.20.3
Conditioned reinforcement - inactives0.30.40.60.7-0.70.80.40.50.50.6
Conditioned locomotion3.85.06.81.9-2.32.62.32.41.82.3
Patch foraging indifference point 0 sec1.22.24.92.2-1.51.61.21.40.91.1
Patch foraging indifference point AUC0.50.71.10.6-0.70.50.91.00.91.1
Delay disc. indifference point, 0s delay0.10.10.20.5-0.20.20.40.10.20.2
Delay disc. indifference point, 16s delay0.90.91.7-1.31.0-1.2-0.7-0.9-0.4-0.9
Delay disc. indifference point, 2s delay0.10.10.1-0.1-0.20.30.30.20.30.3
Delay disc. indifference point, 24s delay0.30.30.6-0.70.6-0.5-0.5-0.7-0.3-0.8
Delay disc. indifference point, 4s delay0.50.51.10.5-0.60.61.00.61.10.5
Delay disc. indifference point, 8s delay0.10.10.3-0.40.4-0.5-0.4-0.40.2-0.2
Indifference point function ln k0.20.30.70.00.3-0.0-0.6-0.6-0.6-0.8
Indifference point function log k0.20.30.70.00.3-0.0-0.6-0.6-0.6-0.8
Patch foraging total patch changes 0 sec1.32.45.52.3-1.61.71.31.51.01.2
Patch foraging total patch changes 12 sec0.40.50.80.8-0.70.50.60.90.60.8
Patch foraging total patch changes 18 sec0.71.01.31.0-1.00.91.11.11.00.9
Patch foraging total patch changes 24 sec0.61.11.31.0-1.10.91.11.11.11.0
Patch foraging total patch changes 6 sec1.72.63.31.8-1.61.61.61.71.41.4
Patch foraging time to switch 0 sec0.50.91.9-1.41.0-0.9-0.9-1.0-0.6-0.8
Patch foraging water rate 0 sec0.30.61.71.3-0.80.80.50.80.30.6
Patch foraging water rate 12 sec0.00.10.10.30.00.2-0.3-0.2-0.3-0.4
Patch foraging water rate 18 sec0.40.61.0-0.30.6-0.4-1.0-0.9-0.9-1.0
Patch foraging water rate 24 sec0.00.00.10.30.1-0.10.00.0-0.10.0
Patch foraging water rate 6 sec0.10.10.40.7-0.30.60.1-0.1-0.1-0.3
Seeking ratio, delayed vs. immediate footshock0.60.81.1-1.10.9-0.9-0.8-0.7-1.1-0.4
Distance traveled before self-admin1.21.62.6-1.61.3-1.5-1.3-1.1-1.2-0.8
Distance traveled after self-admin0.50.61.0-1.00.8-0.9-0.7-0.7-0.7-0.4
Extensor digitorum longus weight9.838.442.35.8-6.56.06.46.26.46.0
Bone: elastic displacement2.12.53.2-1.31.5-1.2-1.7-1.7-1.7-1.8
Bone: elastic work0.81.01.6-1.31.0-1.2-1.0-1.0-0.8-0.8
Bone: endosteal estimation0.20.51.9-0.90.7-1.4-0.5-0.2-0.10.3
Bone: endosteal perimeter0.10.30.9-0.40.5-0.9-0.6-0.3-0.50.0
Epididymis fat weight0.20.61.70.4-0.70.20.60.90.91.3
Delta time in closed arm before/after self-admin0.60.50.90.9-0.70.80.80.70.60.6
Delta time in open arm before/after self-admin1.51.52.0-1.41.2-1.4-1.3-1.2-1.0-0.9
Diff in mean of infusions in LGA sessions0.70.81.2-1.11.0-1.0-0.8-1.0-0.7-0.8
Delay discount exponential model param0.10.10.30.3-0.00.2-0.20.1-0.50.1
Extinction: sum of active levers before priming1.31.51.9-1.21.2-1.4-1.2-1.2-1.2-1.1
Active lever presses in extinction session 60.60.60.8-0.60.7-0.7-0.8-0.9-0.8-0.7
Bone: final force0.40.61.40.5-0.70.10.70.90.91.2
Bone: final moment0.40.61.20.6-0.70.20.70.90.91.1
Food consumed during 24 hour testing period0.10.20.50.1-0.30.10.40.50.40.7
Glucose0.81.32.5-0.71.0-0.6-1.2-1.2-1.6-1.4
Heart weight0.10.10.2-0.50.2-0.3-0.3-0.2-0.2-0.0
Delay discount hyperbolic model param0.10.10.30.20.00.1-0.30.1-0.60.1
Intermittent access intake day 1-15 change0.00.10.4-0.0-0.10.30.10.10.6-0.0
Intermittent access intake escalation0.00.10.30.1-0.10.40.10.10.6-0.1
Intermittent access intake escalation 20.20.20.4-0.20.5-0.5-0.3-0.50.1-0.7
Intermitt. access day 1 inactive lever presses0.10.51.21.1-0.60.90.70.40.7-0.0
Intermitt. access day 15 inactive lever presses0.20.40.90.6-0.70.90.60.40.40.3
Intermitt. access escalation Index0.30.40.7-0.80.5-0.3-0.5-0.6-0.8-0.8
Intermittent access day 1 total infusions0.71.22.3-0.71.1-0.5-1.2-1.1-1.5-1.1
Intermittent access day 15 total infusions0.10.20.5-0.20.40.3-0.5-0.4-0.5-0.7
Intermittent access terminal intake (last 3 days)0.10.10.30.40.10.5-0.2-0.2-0.1-0.5
Intermittent access total infusions0.30.30.6-0.20.50.1-0.7-0.6-0.8-0.7
Intermittent access day 1 locomotion0.10.20.5-0.40.20.6-0.3-0.1-0.7-0.2
Intermittent access day 15 total locomotion0.40.60.90.6-0.81.00.70.90.70.8
Intermittent access total locomotion0.20.31.20.4-0.41.10.20.4-0.00.2
Intermittent access standard deviation0.20.40.60.4-0.70.80.60.60.70.5
Left kidney weight0.10.51.3-0.20.6-0.5-0.8-0.6-1.1-0.6
Right kidney weight0.20.71.21.1-0.90.80.70.90.50.9
Cocaine induced anxiety1.62.34.72.2-1.51.71.51.31.21.1
Post-drug Anxiety1.71.92.51.6-1.31.31.51.41.21.2
Baseline Anxiety0.91.12.9-1.71.0-1.4-0.8-0.7-0.4-0.6
Tail length2.911.314.2-3.13.5-3.5-3.8-3.1-3.7-2.7
Length with tail1.87.911.4-3.03.0-3.4-3.1-2.4-2.8-1.7
Length without tail0.10.41.0-1.00.4-1.0-0.20.10.10.6
Times rat made contact with spout1.41.62.5-1.11.2-0.9-1.2-1.4-1.4-1.6
Lifetime Intake0.10.10.30.4-0.10.6-0.10.0-0.2-0.1
Liver weight, left0.10.10.3-0.20.4-0.6-0.30.0-0.20.2
Liver weight, right0.20.30.6-0.40.6-0.8-0.8-0.4-0.7-0.2
Locomotor activity0.10.20.30.5-0.50.40.40.30.50.4
Locomotor testing distance0.30.60.7-0.60.7-0.7-0.8-0.8-0.8-0.8
Locomotor testing rearing0.51.01.6-0.41.0-0.7-1.1-1.0-1.2-1.3
Locomotion in novel chamber3.84.95.72.1-2.22.12.32.32.02.4
Locomotion in novel chamber post-restriction3.55.87.22.4-2.41.92.52.42.72.4
Fecal boli incidents, locomotor time 10.20.30.6-0.30.6-0.3-0.6-0.4-0.8-0.5
Change in fecal boli incidents, locomotor task0.00.00.2-0.1-0.10.40.1-0.1-0.3-0.1
Time >=10cm from walls, locomotor time 11.11.21.71.3-1.10.91.01.10.81.2
Bouts of movement, locomotor time 11.01.11.31.0-1.11.11.20.91.20.8
Total resting periods, locomotor time 11.71.92.21.4-1.41.41.51.31.41.2
Rest time, locomotor task time 10.10.10.60.40.20.2-0.2-0.2-0.8-0.4
Distance moved, locomotor task time 10.20.41.1-1.00.5-0.6-0.4-0.60.0-0.5
Vertical activity count, locomotor time 10.10.20.6-0.7-0.1-0.10.20.10.70.1
Time >=10cm from walls, locomotor time 20.81.21.6-1.21.1-1.0-1.1-1.2-1.0-1.1
Bouts of movement, locomotor time 22.43.86.01.6-2.02.02.11.72.41.5
Total resting periods, locomotor time 22.13.65.21.7-2.02.02.11.72.31.5
Rest time, locomotor task time 20.20.20.70.8-0.40.70.10.2-0.50.0
Distance moved, locomotor task time 20.30.31.1-1.00.5-0.7-0.3-0.40.1-0.3
Vertical activity count, locomotor time 20.10.10.6-0.4-0.1-0.10.4-0.10.8-0.1
Light reinforcement 13.79.110.32.9-3.23.13.13.13.02.8
Light reinforcement 21.01.62.01.4-1.41.41.21.21.01.1
Bone: marrow area0.20.41.6-0.80.6-1.3-0.4-0.2-0.00.3
Bone: maximum diameter0.10.20.40.6-0.40.20.20.50.30.5
Bone: maximum force0.40.61.70.2-0.5-0.20.70.91.01.3
Bone: maximum moment0.30.61.50.3-0.6-0.10.70.91.01.2
Mean time between licks in bursts1.84.45.02.1-2.21.92.02.12.12.1
Mean num. licks in bursts0.20.30.50.2-0.60.50.70.60.70.7
Cd content in liver4.75.36.7-1.72.6-2.4-2.4-2.2-2.5-2.2
Co content in liver2.83.34.0-1.31.8-1.6-2.0-1.9-2.0-2.0
Cu content in liver1.61.92.2-1.41.4-1.4-1.4-1.5-1.2-1.4
Fe content in liver3.74.55.1-2.22.1-1.9-2.1-2.2-2.1-2.2
K content in liver3.63.53.81.8-1.91.81.91.82.01.8
Mg content in liver0.50.50.70.7-0.70.70.80.60.80.6
Mn content in liver0.30.30.70.9-0.70.80.30.30.40.2
Na content in liver0.00.00.1-0.2-0.20.20.10.00.30.1
Rb content in liver5.46.37.22.4-2.72.42.52.52.62.5
Se content in liver0.20.30.40.5-0.60.60.40.50.50.5
Sr content in liver0.00.00.10.4-0.10.20.10.10.1-0.0
Zn content in liver0.00.00.00.20.1-0.1-0.0-0.0-0.1-0.0
Bone: minimum diameter0.30.61.30.6-0.70.10.60.90.81.2
Time in familiar zone, hab. session 10.10.10.3-0.10.3-0.0-0.4-0.4-0.5-0.5
Time in novel zone, hab. session 13.33.33.8-1.81.9-1.9-1.9-1.8-1.8-1.6
Total zone transitions, hab. session 10.60.91.40.5-0.90.71.01.01.11.2
Total locomotion distance, hab. session 10.81.22.60.6-0.90.41.01.31.21.6
Locomotion velocity, hab. session 11.92.74.41.2-1.51.11.71.91.82.1
Time in familiar zone, hab. session 20.20.20.3-0.20.3-0.2-0.5-0.4-0.6-0.5
Time in novel zone, hab. session 20.30.30.4-0.40.6-0.6-0.5-0.6-0.5-0.6
Total zone transitions, hab. session 20.00.00.1-0.20.00.10.1-0.10.2-0.1
Total locomotion distance, hab. session 20.10.10.2-0.1-0.1-0.20.30.30.40.5
Locomotion velocity, hab. session 20.20.30.60.2-0.40.10.60.60.70.8
Novel to familiar place preference ratio1.21.31.9-1.41.1-1.2-1.2-1.1-1.1-0.9
Novelty place preference1.41.51.7-1.31.1-1.2-1.3-1.2-1.2-1.1
Time in novel zone, NPP test1.81.92.2-1.51.3-1.4-1.5-1.4-1.4-1.3
Total zone transitions, NPP test0.40.50.60.8-0.70.70.80.60.80.6
Total locomotion distance, NPP test0.20.30.50.5-0.40.10.50.60.50.7
Locomotion velocity, NPP test0.50.81.11.0-0.80.60.81.00.91.0
Intraocular pressure0.10.10.2-0.20.3-0.2-0.3-0.3-0.3-0.4
Delta distance traveled before/after self-admin0.10.10.30.6-0.40.40.40.30.20.2
Delta ambulatory time before/after self-admin0.40.40.91.0-0.60.60.70.60.60.5
Parametrial fat weight0.00.10.20.3-0.30.50.50.30.3-0.0
Pavlov. Cond. lever latency2.73.44.21.8-1.91.81.82.01.61.9
Pavlov. Cond. magazine entry latency2.83.54.3-2.02.0-2.1-1.9-1.9-1.6-1.7
Pavlov. Cond. change in total contacts2.42.53.1-1.61.6-1.8-1.6-1.7-1.4-1.5
Pavlov. Cond. index score3.74.75.4-2.22.3-2.2-2.2-2.3-1.9-2.2
Pavlov. Cond. latency score3.54.45.1-2.12.2-2.1-2.1-2.2-1.8-2.1
Pavlov. Cond. lever contacts2.93.44.1-1.91.9-1.8-1.7-2.0-1.5-2.0
Pavlov. Cond. magazine entry number4.25.36.22.5-2.42.52.32.42.02.1
Pavlov. Cond. intertrial magazine entries0.00.00.10.2-0.20.20.10.30.20.3
Pavlov. Cond. lever-magazine prob. diff.3.13.94.4-2.02.1-2.0-1.9-2.1-1.7-2.0
Pavlov. Cond. response bias4.04.95.6-2.42.3-2.3-2.2-2.3-1.9-2.2
Pavlov. Cond. lever latency0.10.10.20.3-0.30.40.40.20.40.1
Pavlov. Cond. magazine entry latency0.30.40.8-0.60.7-0.9-0.4-0.5-0.5-0.4
Pavlov. Cond. change in total contacts0.71.21.6-1.01.1-1.2-1.1-0.9-1.3-0.7
Pavlov. Cond. index score0.20.30.8-0.60.6-0.9-0.5-0.4-0.6-0.2
Pavlov. Cond. latency score0.10.20.5-0.50.5-0.7-0.3-0.2-0.4-0.0
Pavlov. Cond. lever contacts0.40.50.8-0.70.7-0.8-0.8-0.6-0.9-0.5
Pavlov. Cond. magazine entry number0.50.61.10.9-0.91.10.60.70.70.6
Pavlov. Cond. intertrial magazine entries0.50.71.20.5-1.01.10.90.71.00.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.50.4-0.7-0.3-0.2-0.3-0.0
Pavlov. Cond. response bias0.40.50.9-0.70.7-1.0-0.8-0.6-0.8-0.4
Time in closed arm before self-admin1.92.44.5-2.11.6-1.8-1.5-1.3-1.1-1.1
Time in closed arm after self-admin0.20.20.6-0.60.5-0.8-0.2-0.3-0.0-0.2
Time in open arm before self-admin1.21.32.61.4-1.21.61.01.10.40.9
Time in open arm after self-admin0.80.91.5-1.20.9-0.8-1.1-0.8-1.1-0.5
Bone: periosteal estimation0.10.20.6-0.10.0-0.7-0.00.30.30.7
Bone: periosteal perimeter0.10.20.6-0.20.4-0.8-0.6-0.3-0.4-0.1
Bone: post-yield work0.10.10.3-0.30.1-0.50.10.20.50.4
Progressive ratio test 1 active lever presses0.10.10.50.4-0.30.70.10.2-0.10.1
Progressive ratio test 1 breakpoint0.10.10.30.2-0.20.60.10.2-0.10.1
Progressive ratio test 1 inactive lever presses1.31.82.91.7-1.41.71.31.11.10.9
Progressive ratio test 2 active lever presses0.00.00.10.2-0.10.4-0.1-0.00.0-0.1
Progressive ratio test 2 breakpoint0.00.00.10.3-0.10.3-0.1-0.1-0.1-0.2
Progressive ratio test 2 inactive lever presses0.00.10.40.2-0.20.6-0.00.1-0.1-0.0
Incentive Sensitization - Responses0.30.40.6-0.30.6-0.5-0.8-0.6-0.7-0.6
Incentive Sensitization - Breakpoint0.20.30.4-0.30.5-0.4-0.6-0.5-0.5-0.6
Sum of active levers in priming session hrs 5-61.81.62.8-1.71.3-1.6-1.1-1.2-1.0-0.9
Progressive ratio0.71.01.81.1-0.90.60.91.11.31.1
Food seeking constrained by brief footshock0.50.61.11.0-0.70.30.70.90.61.0
Seeking ratio, punishment vs. effort0.00.10.20.1-0.30.20.20.3-0.10.4
Retroperitoneal fat weight0.62.63.11.6-1.81.51.61.61.71.6
Reaction time number correct0.71.41.91.3-1.41.41.11.21.01.0
Reaction time mean minus median0.82.02.8-1.71.5-1.6-1.2-1.4-1.2-1.2
Reaction time mean minus median AUC0.71.82.3-1.51.4-1.4-1.2-1.3-1.2-1.2
Reaction time num false alarms3.55.06.82.6-2.22.22.22.22.12.0
Reaction time num false alarms AUC4.36.88.73.0-2.62.62.62.62.52.4
Reaction time trials correct on left0.71.41.91.3-1.41.41.11.21.01.0
Reaction time trials on left0.71.31.81.2-1.31.41.01.20.91.0
Reaction time mean3.65.89.4-3.12.5-2.6-2.2-2.5-1.8-2.0
Reaction time mean AUC3.25.07.8-2.82.4-2.4-2.1-2.3-1.7-2.0
Median of all reaction times4.25.99.5-3.12.5-2.6-2.2-2.5-1.8-2.1
Reaction time omissions1.01.51.9-1.31.4-1.1-1.1-1.3-1.1-1.3
Reaction time false alarm rate2.02.84.02.0-1.61.61.71.61.71.5
Reaction time premature initiation rate0.10.10.3-0.50.3-0.4-0.3-0.4-0.0-0.4
Reaction time premature initiations0.00.10.10.1-0.30.30.20.20.40.1
Std. dev. reaction times3.05.57.8-2.82.5-2.6-2.1-2.3-1.9-1.9
Reaction time trials completed0.71.31.81.2-1.31.41.01.20.91.0
Reaction time trials AUC0.61.21.71.2-1.21.31.01.10.90.9
Run reversals in cocaine runway, females1.01.01.81.3-1.00.70.91.00.91.2
Run reversals in cocaine runway, males1.11.11.51.0-1.10.81.21.11.11.1
Latency to leave start box in cocaine runway4.04.65.82.0-2.22.22.42.12.21.8
Latency to leave start box in cocaine runway, F1.61.82.71.1-1.41.61.61.31.20.9
Latency to leave start box in cocaine runway, M4.44.15.02.2-2.11.72.02.02.12.0
Std. dev. time between licks in bursts3.44.65.82.4-2.32.42.12.02.21.6
Total sessions with >9 infusions2.73.34.12.0-1.92.01.71.91.41.8
Short access day 1 total inactive lever presses2.43.14.11.6-1.81.41.92.01.51.9
Short access day 10 total inactive lever presses0.10.20.50.5-0.30.10.40.30.70.3
Short access day 1 total infusions2.73.65.12.3-2.11.61.82.01.42.0
Short access day 10 total infusions0.10.20.50.40.10.5-0.4-0.4-0.4-0.7
Short access total infusions0.30.40.80.9-0.60.90.50.50.30.4
Short access day 1 locomotion3.34.14.72.0-2.21.92.12.11.82.1
Short access day 10 total locomotion0.20.30.70.5-0.50.90.40.60.30.4
Short access total locomotion2.53.04.31.5-1.82.11.71.81.31.7
One hour access (0.3 mA shock)0.20.20.4-0.40.5-0.4-0.5-0.5-0.4-0.6
Compulsive drug intake1.01.21.71.1-1.10.71.31.11.11.1
One hour access (shock baseline)0.50.81.0-0.81.0-0.5-1.0-0.9-1.0-1.0
Social response proportion0.40.40.6-0.80.6-0.6-0.6-0.7-0.6-0.6
Social responses0.00.00.10.3-0.10.00.00.20.10.2
Social time1.62.22.6-1.61.5-1.2-1.4-1.6-1.4-1.6
Soleus weight1.64.65.22.0-2.21.72.32.32.32.3
Bone: stiffness0.71.12.60.7-0.80.21.01.21.31.6
Tibialis anterior weight4.414.816.83.8-4.13.84.03.83.93.5
Time to tail flick, vehicle, before self-admin0.20.20.8-0.90.3-0.2-0.2-0.2-0.1-0.4
Time to tail flick, vehicle, after self-admin0.81.11.6-1.31.0-0.9-0.9-1.1-0.9-1.1
Time to tail flick, test, before self-admin2.93.04.01.5-1.71.42.01.81.91.7
Time to tail flick, test, after self-admin3.43.64.21.6-1.91.72.02.02.02.0
Delta time to tail flick, vehicle, before/after SA0.30.20.4-0.20.5-0.5-0.5-0.6-0.5-0.6
Delta time to tail flick, test, before/after SA0.10.10.3-0.50.3-0.2-0.4-0.3-0.3-0.3
Tibia length0.30.93.3-1.30.9-1.8-0.7-0.4-0.40.3
Ambulatory time before self-admin1.52.23.1-1.81.6-1.7-1.5-1.3-1.3-1.0
Ambulatory time after self-admin0.40.50.7-0.60.8-0.8-0.7-0.7-0.7-0.5
Bone: tissue strength0.00.00.10.10.2-0.2-0.3-0.1-0.2-0.1
Total heroin consumption1.51.82.3-1.41.4-1.4-1.2-1.5-0.9-1.5
Bone: trabecular number1.21.92.4-1.31.4-1.5-1.5-1.3-1.5-1.1
Bone: trabecular spacing1.21.62.21.0-1.31.21.41.21.51.3
Bone: trabecular thickness6.98.69.7-2.63.0-2.9-3.1-2.9-3.1-2.8
Bone: trabecular tissue density0.00.00.1-0.1-0.1-0.2-0.10.20.00.3
Water consumed over 24 hours0.00.00.10.00.10.10.0-0.1-0.2-0.3
Number of responses in last shaping day0.00.00.3-0.50.00.10.0-0.10.1-0.1