Hub : Genes

Slc39a10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Slc39a10 0.03 0.02 1.6e-03 0 0.01 0.01 0 8.6e-02 7.1e-02 5.0e-02 1.9e-01
2 Adipose alternative TSS NM_001108796.2 0.02 0.02 2.4e-03 0.01 0.01 0.01 0.01 9.7e-03 1.2e-02 2.7e-02 2.9e-02
3 Adipose isoform ratio NM_001108796.2 0.02 0.02 2.5e-03 0.01 0.01 0.01 0.01 9.7e-03 1.4e-02 4.8e-02 2.7e-02
4 IL intron excision ratio chr9_62370704_62423146 0.2 0.14 7.7e-03 0.06 0.03 0.05 0.02 1.8e-02 5.4e-02 2.1e-02 8.8e-02
5 PL alternative TSS NM_001108796.2 0.03 0.02 9.2e-03 0.02 0.01 0.01 0.01 6.7e-03 3.5e-02 3.4e-02 1.7e-02
6 PL intron excision ratio chr9_62406020_62423146 0.03 0.04 9.9e-03 0.01 0.01 0.01 0.01 3.9e-02 1.2e-02 1.4e-02 3.3e-02
7 Brain gene expression Slc39a10 0.04 0.04 2.9e-03 0.02 0.01 0.02 0.01 2.5e-03 1.3e-02 4.6e-03 1.6e-02
8 pVTA mRNA stability Slc39a10 0.06 0.04 7.7e-05 0.06 0.04 0.04 0.04 3.0e-05 2.2e-04 1.8e-04 2.1e-04
9 Adipose alternative TSS XM_006244936.5 0.04 0.03 1.7e-05 0.04 0.04 0.04 0.04 2.0e-05 4.8e-05 2.8e-05 4.2e-05
10 Adipose gene expression Slc39a10 0.02 0.02 7.5e-03 0.02 0.01 0.01 0.01 6.2e-03 5.0e-02 4.2e-02 4.0e-02
11 PL intron excision ratio chr9_62370704_62423146 0.02 0.02 9.8e-03 0.02 0.02 0 0.01 6.6e-03 5.1e-03 1.0e-01 1.0e-02
12 PL mRNA stability Slc39a10 0.15 0.09 4.5e-08 0.05 0.07 0.07 0.07 1.6e-06 4.5e-08 1.8e-08 1.8e-08
13 Brain mRNA stability Slc39a10 0.05 0.04 7.1e-03 0 0.01 0 0.02 2.2e-01 3.6e-02 3.4e-01 6.0e-03
14 Liver isoform ratio XM_063267375.1 0.05 0.04 2.7e-03 0 0.02 0 0 2.8e-01 6.2e-03 9.3e-02 9.3e-02
15 NAcc mRNA stability Slc39a10 0.09 0.13 3.9e-04 0.02 0.01 0.01 0.02 2.9e-04 4.7e-03 5.4e-03 7.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density2.34.07.52.4-2.7-2.71.9-2.7-2.1-1.92.02.0-2.01.7-1.6-1.3-0.20.5
Area under the delay curve0.50.62.2-0.50.50.5-0.70.41.10.7-1.5-0.40.4-1.40.3-0.6-0.9-0.7
BMI with tail4.314.921.4-4.64.44.4-4.54.44.04.2-3.6-4.64.6-2.54.13.01.8-0.2
BMI without tail0.51.62.6-1.51.31.3-1.61.21.11.3-1.0-1.41.4-0.31.61.31.20.4
Body weight0.94.07.02.2-2.2-2.21.9-2.3-2.6-2.32.22.0-2.02.6-1.7-0.80.70.7
Weight adjusted by age1.52.33.91.6-1.7-1.71.5-1.7-0.8-1.50.71.5-1.5-0.4-2.0-1.9-1.9-1.1
Bone surface2.03.66.62.3-2.6-2.61.8-2.4-2.1-1.82.01.9-1.91.8-1.5-1.00.00.6
Bone volume2.44.48.32.6-2.9-2.92.0-2.8-2.1-2.02.02.2-2.21.6-1.8-1.5-0.40.3
Breakpoint value in progressive ratio session0.60.72.60.4-0.3-0.30.7-0.3-1.2-0.71.60.4-0.41.6-0.50.91.0-0.3
Number of licking bursts0.10.20.6-0.40.50.5-0.60.50.60.4-0.80.0-0.0-0.70.2-0.1-0.3-0.6
Context. condit. distance diff. score2.32.74.4-1.61.81.8-2.11.81.61.9-1.6-1.81.8-0.81.91.61.20.9
Locomotion velocity, session 11.61.73.4-1.61.71.7-1.11.81.31.2-1.3-1.41.4-1.21.00.8-0.0-0.2
Locomotion distance, session 11.31.62.6-1.41.31.3-1.51.30.91.4-0.9-1.51.5-0.01.61.51.51.0
Locomotion velocity, session 22.22.53.8-2.01.91.9-1.71.91.81.9-1.6-1.61.6-1.31.71.20.60.1
Locomotion distance, session 20.30.41.1-0.70.60.6-0.30.60.10.40.2-0.50.50.50.71.01.11.1
Locomotion velocity, session 30.70.83.5-0.50.30.3-0.40.3-0.30.40.6-0.50.51.20.81.51.71.9
Locomotion distance, session 30.20.20.6-0.40.40.4-0.00.4-0.3-0.00.4-0.60.60.60.10.80.70.6
Stereotopy head waving bouts, day 30.81.01.7-1.21.31.3-0.91.30.60.8-0.4-1.11.1-0.11.01.30.80.7
Stereotopy head waving duration, day 30.60.71.8-0.90.90.9-0.60.90.20.60.0-0.80.80.50.91.41.21.1
Locomotion velocity, session 72.72.94.4-1.92.02.0-2.02.02.12.0-2.0-1.61.6-1.81.61.00.1-0.5
Locomotion distance, session 70.30.30.8-0.50.50.5-0.90.40.70.9-0.7-0.30.3-0.30.80.40.50.2
Stereotopy head waving bouts, day 70.20.20.5-0.60.70.70.20.7-0.0-0.10.1-0.70.7-0.0-0.20.4-0.1-0.4
Stereotopy head waving duration, day 70.30.40.9-0.80.90.9-0.20.90.10.20.1-0.90.90.10.30.90.40.2
Locomotion velocity, session 82.12.54.6-1.71.81.8-1.61.82.01.6-2.1-1.51.5-2.11.10.3-0.7-0.7
Locomotion distance, session 82.02.94.3-1.71.81.8-2.01.91.41.9-1.2-1.71.7-0.32.12.01.71.6
Degree of sensitization distance0.30.30.70.3-0.4-0.4-0.3-0.40.50.3-0.60.6-0.6-0.70.1-0.8-0.6-0.8
Degree of sensitization stereotypy0.10.10.3-0.30.40.40.30.3-0.1-0.20.1-0.40.4-0.1-0.30.1-0.3-0.6
Conditioned locomotion3.54.15.82.3-2.3-2.32.4-2.2-2.3-2.32.42.1-2.11.7-2.0-1.3-0.60.3
Cocaine response after cond. corrected2.83.46.92.0-1.9-1.91.9-2.0-1.3-1.80.91.7-1.7-0.2-2.3-2.6-2.3-1.8
Cocaine response after cond. not corrected3.13.78.12.0-2.0-2.01.8-2.0-1.2-1.70.71.8-1.8-0.3-2.3-2.8-2.4-2.1
Cocaine response before conditioning0.20.30.9-0.50.40.4-0.70.60.70.7-0.9-0.20.2-0.60.50.10.1-0.5
Saline control response0.50.73.0-0.20.10.1-0.40.30.10.60.40.0-0.00.81.21.21.61.7
Bone: connectivity density0.91.43.11.5-1.8-1.80.9-1.7-1.0-1.00.91.3-1.30.7-0.9-1.1-0.40.1
Bone: cortical apparent density5.67.712.2-3.02.82.8-3.52.83.13.3-3.2-3.23.2-2.03.11.91.40.2
Bone: cortical area0.10.20.60.1-0.2-0.20.4-0.1-0.6-0.40.7-0.10.10.8-0.20.40.50.5
Bone: cortical porosity2.72.94.01.9-2.0-2.01.9-1.8-2.0-2.02.01.9-1.91.6-1.7-1.0-0.30.2
Bone: cortical porosity4.54.96.72.5-2.6-2.62.4-2.4-2.6-2.52.62.3-2.32.1-2.2-1.3-0.30.3
Bone: cortical thickness0.91.62.8-1.61.61.6-1.11.61.01.1-0.7-1.71.7-0.61.11.20.60.4
Bone: cortical thickness1.11.32.3-1.31.41.4-0.81.41.20.7-1.2-1.41.4-1.50.30.0-0.9-1.1
Bone: cortical tissue density5.67.611.9-3.02.82.8-3.52.83.13.3-3.1-3.23.2-2.03.11.91.40.2
Condit. Reinf. active minus inactive responses1.21.42.01.1-1.4-1.41.4-1.3-1.3-1.41.11.1-1.10.8-1.4-1.1-0.6-0.7
Condit. Reinf. active-inactive response ratio0.80.81.30.9-1.1-1.11.1-1.0-0.8-1.00.70.8-0.80.3-1.1-1.1-0.8-0.7
Condit. Reinf. active responses1.51.92.61.4-1.6-1.61.5-1.5-1.4-1.51.21.6-1.60.8-1.6-1.3-0.8-1.1
Condit. Reinf. inactive responses0.10.10.40.3-0.3-0.30.3-0.3-0.4-0.30.40.6-0.60.3-0.3-0.10.0-0.5
Incentive salience index mean1.31.72.41.2-1.5-1.51.4-1.4-1.1-1.40.91.3-1.30.3-1.5-1.5-1.1-1.2
Condit. Reinf. lever presses0.50.71.20.9-1.0-1.00.8-1.0-0.6-0.80.51.0-1.00.1-0.9-1.1-0.8-1.1
Condit. Reinf. active minus inactive responses5.16.69.72.8-2.8-2.82.7-2.7-2.2-2.71.62.9-2.90.6-3.1-3.1-2.4-1.9
Condit. Reinf. active-inactive response ratio4.04.69.52.1-2.0-2.02.3-2.0-1.4-2.21.02.1-2.1-0.3-2.8-3.1-2.9-2.4
Condit. Reinf. active responses2.02.85.11.8-1.9-1.91.5-1.8-1.1-1.50.61.8-1.80.1-1.9-2.3-1.7-1.8
Condit. Reinf. inactive responses0.50.61.2-0.80.60.6-1.10.80.81.0-0.9-0.70.7-0.21.10.90.90.1
Condit. Reinf. lever presses0.40.62.1-0.30.10.1-0.60.30.90.5-1.2-0.20.2-1.40.0-0.9-1.0-1.5
Condit. Reinf. lever reinforcers received1.82.64.81.7-1.8-1.81.4-1.6-1.1-1.50.51.8-1.8-0.0-1.9-2.2-1.8-1.8
Conditioned reinforcement - actives0.71.25.4-0.90.70.7-1.00.7-0.20.80.3-0.60.61.51.21.72.30.8
Conditioned reinforcement - inactives0.30.52.7-0.20.20.2-0.50.2-0.20.20.60.2-0.20.80.71.01.11.6
Conditioned locomotion0.91.24.8-1.10.80.8-1.30.70.21.4-0.1-0.90.91.01.51.52.20.3
Patch foraging indifference point 0 sec0.71.33.7-1.11.01.0-1.11.11.41.1-1.9-0.90.9-1.50.5-0.3-0.5-1.8
Patch foraging indifference point AUC0.30.41.00.7-0.8-0.80.2-0.70.1-0.2-0.30.7-0.7-0.6-0.4-1.0-1.0-0.5
Delay disc. indifference point, 0s delay2.42.73.9-1.91.81.8-2.01.81.61.9-1.5-1.71.7-0.81.91.71.00.7
Delay disc. indifference point, 16s delay0.20.20.8-0.20.10.1-0.30.10.60.3-0.80.0-0.0-0.9-0.0-0.4-0.7-0.4
Delay disc. indifference point, 2s delay0.50.51.9-0.40.40.4-0.30.40.70.3-1.0-0.40.4-1.2-0.2-0.7-1.0-1.4
Delay disc. indifference point, 24s delay0.10.20.3-0.50.50.5-0.40.40.40.3-0.3-0.40.4-0.40.40.40.00.5
Delay disc. indifference point, 4s delay2.02.14.9-1.51.41.4-1.81.31.91.8-2.2-1.41.4-1.71.40.2-0.1-0.1
Delay disc. indifference point, 8s delay0.40.41.40.5-0.5-0.50.3-0.50.2-0.1-0.60.6-0.6-0.8-0.5-1.2-1.2-0.7
Indifference point function ln k0.61.02.3-1.01.01.0-0.71.01.10.7-1.1-1.01.0-1.50.2-0.2-0.9-1.5
Indifference point function log k0.61.02.3-1.01.01.0-0.71.01.10.7-1.1-1.01.0-1.50.2-0.2-0.9-1.5
Patch foraging total patch changes 0 sec0.61.23.5-1.11.01.0-1.01.01.31.0-1.9-0.80.8-1.30.5-0.3-0.4-1.8
Patch foraging total patch changes 12 sec0.00.10.3-0.0-0.1-0.1-0.1-0.10.10.3-0.6-0.00.0-0.00.0-0.40.2-0.6
Patch foraging total patch changes 18 sec1.11.73.6-1.41.41.4-1.51.41.81.5-1.9-1.01.0-1.71.20.4-0.2-0.6
Patch foraging total patch changes 24 sec0.10.10.5-0.20.20.2-0.30.20.40.5-0.7-0.20.2-0.30.5-0.00.2-0.5
Patch foraging total patch changes 6 sec0.91.33.9-0.80.70.7-0.90.81.61.1-2.0-0.70.7-2.00.5-0.6-1.0-1.6
Patch foraging time to switch 0 sec0.61.15.5-0.20.40.40.00.3-0.6-0.01.4-0.20.21.50.81.81.72.3
Patch foraging water rate 0 sec0.30.64.80.3-0.4-0.40.1-0.30.1-0.1-0.70.4-0.4-0.6-0.7-1.2-0.9-2.2
Patch foraging water rate 12 sec0.51.04.8-0.40.40.4-0.50.50.90.3-1.5-0.50.5-1.6-0.5-1.1-1.4-2.2
Patch foraging water rate 18 sec0.10.20.80.3-0.4-0.40.4-0.3-0.3-0.5-0.10.1-0.1-0.1-0.7-0.8-0.6-0.9
Patch foraging water rate 24 sec0.10.10.20.3-0.2-0.20.2-0.1-0.4-0.40.20.4-0.40.4-0.3-0.20.10.2
Patch foraging water rate 6 sec0.30.41.0-0.50.30.3-0.50.30.70.5-1.0-0.60.6-0.90.0-0.5-0.4-1.0
Seeking ratio, delayed vs. immediate footshock1.51.93.41.5-1.3-1.31.8-1.4-1.7-1.71.71.5-1.51.4-1.3-0.8-0.10.1
Distance traveled before self-admin2.02.64.31.8-1.5-1.51.9-1.6-2.1-2.01.81.8-1.81.8-1.7-0.80.00.1
Distance traveled after self-admin0.20.21.30.3-0.0-0.00.60.0-0.3-0.60.30.3-0.3-0.0-0.7-0.2-0.5-1.2
Extensor digitorum longus weight2.710.615.7-3.63.43.4-3.83.63.33.8-2.9-3.73.7-1.64.03.12.31.1
Bone: elastic displacement0.60.72.80.5-0.4-0.40.7-0.3-0.0-0.5-0.10.5-0.5-0.9-1.0-1.4-1.7-1.5
Bone: elastic work1.41.83.21.6-1.8-1.81.4-1.7-1.3-1.31.21.5-1.50.7-1.4-1.3-0.7-0.4
Bone: endosteal estimation3.57.611.73.2-3.4-3.43.0-3.3-3.2-2.92.92.9-2.92.6-2.6-1.7-0.30.2
Bone: endosteal perimeter2.55.48.42.8-2.9-2.92.6-2.8-2.6-2.52.32.3-2.31.9-2.4-1.7-0.6-0.2
Epididymis fat weight0.41.32.71.0-1.1-1.11.3-1.2-1.6-1.41.70.9-0.91.6-0.9-0.20.40.4
Delta time in closed arm before/after self-admin0.20.20.4-0.50.50.5-0.60.50.50.4-0.3-0.40.4-0.60.30.4-0.20.0
Delta time in open arm before/after self-admin8.07.911.13.3-3.2-3.23.3-3.2-2.5-3.31.73.1-3.11.1-3.3-3.1-2.0-0.3
Diff in mean of infusions in LGA sessions0.00.00.2-0.0-0.1-0.1-0.2-0.1-0.00.10.4-0.20.20.20.10.40.30.2
Delay discount exponential model param0.50.51.90.4-0.3-0.30.5-0.3-0.9-0.61.40.2-0.21.4-0.10.81.00.7
Extinction: sum of active levers before priming0.50.52.60.5-0.4-0.40.6-0.4-1.2-0.60.80.3-0.31.6-0.40.41.00.2
Active lever presses in extinction session 61.11.11.91.2-1.2-1.21.1-1.2-1.4-1.11.11.1-1.11.4-1.1-0.50.3-0.4
Bone: final force2.23.58.11.8-2.0-2.01.8-1.8-2.4-1.72.71.5-1.52.8-1.00.31.41.8
Bone: final moment1.82.87.21.5-1.7-1.71.6-1.6-2.1-1.42.51.3-1.32.7-0.70.51.51.8
Food consumed during 24 hour testing period0.50.73.0-0.60.50.5-0.70.40.10.8-0.0-0.50.50.91.11.61.71.1
Glucose1.11.76.2-1.01.01.0-1.10.90.21.0-0.1-0.80.81.21.52.32.51.8
Heart weight0.30.52.20.6-0.5-0.50.8-0.4-0.2-0.80.30.5-0.5-0.6-1.0-1.1-1.5-0.7
Delay discount hyperbolic model param0.50.62.10.4-0.4-0.40.5-0.3-1.0-0.61.50.3-0.31.4-0.20.81.00.7
Intermittent access intake day 1-15 change1.02.13.5-1.81.71.7-1.91.71.11.6-1.4-1.51.5-0.31.41.51.3-0.2
Intermittent access intake escalation1.32.64.1-2.01.91.9-2.01.91.41.8-1.6-1.71.7-0.51.61.51.2-0.3
Intermittent access intake escalation 20.30.31.1-0.60.50.5-0.80.50.30.5-0.6-0.40.40.10.30.60.5-1.0
Intermitt. access day 1 inactive lever presses1.76.511.5-2.82.62.6-3.42.71.62.8-1.6-2.72.70.33.22.83.01.7
Intermitt. access day 15 inactive lever presses0.50.92.4-1.00.90.9-1.51.01.40.9-1.2-0.70.7-1.30.80.6-0.2-0.1
Intermitt. access escalation Index0.40.61.90.7-0.8-0.80.3-0.9-0.1-0.7-0.50.6-0.6-0.5-0.7-1.4-1.0-0.6
Intermittent access day 1 total infusions0.91.55.60.9-1.2-1.20.7-1.2-1.7-0.71.61.0-1.02.4-0.50.31.60.4
Intermittent access day 15 total infusions0.91.46.0-1.10.90.9-1.30.8-0.11.0-0.0-0.90.91.41.31.82.50.5
Intermittent access terminal intake (last 3 days)1.21.66.3-1.21.01.0-1.50.9-0.11.1-0.0-1.01.01.41.32.02.50.2
Intermittent access total infusions0.80.95.1-0.0-0.1-0.1-0.4-0.2-1.00.10.90.1-0.12.10.51.32.30.6
Intermittent access day 1 locomotion0.30.42.0-0.0-0.2-0.20.1-0.3-0.8-0.10.7-0.00.01.40.20.51.30.1
Intermittent access day 15 total locomotion0.30.62.9-0.80.40.4-0.90.4-0.10.7-0.1-0.70.71.00.91.01.7-0.2
Intermittent access total locomotion0.80.93.8-1.00.70.7-1.10.70.00.9-0.0-0.80.81.01.21.42.00.1
Intermittent access standard deviation0.71.53.5-1.41.31.3-1.51.40.31.2-0.5-1.11.10.71.31.91.9-0.1
Left kidney weight0.10.50.90.7-0.7-0.70.8-0.8-0.4-0.80.70.6-0.6-0.1-0.9-0.7-1.0-0.4
Right kidney weight0.00.10.20.1-0.2-0.20.2-0.3-0.1-0.30.1-0.10.1-0.2-0.3-0.4-0.5-0.1
Cocaine induced anxiety0.70.94.40.2-0.4-0.4-0.2-0.41.20.2-1.20.1-0.1-2.1-0.3-1.4-2.0-0.5
Post-drug Anxiety0.80.94.2-0.40.30.3-0.70.31.50.7-1.2-0.60.6-2.10.3-0.5-1.4-0.8
Baseline Anxiety0.10.10.4-0.10.10.10.10.1-0.2-0.10.7-0.10.10.3-0.00.50.3-0.2
Tail length9.035.149.87.0-7.0-7.06.3-7.1-6.4-6.46.07.0-7.05.0-5.6-3.8-1.21.2
Length with tail9.943.258.67.7-7.6-7.67.2-7.6-7.5-7.46.87.4-7.46.0-6.4-4.2-1.01.3
Length without tail3.310.616.23.7-3.6-3.63.8-3.5-4.0-3.93.33.3-3.33.3-3.6-2.3-0.50.0
Times rat made contact with spout0.40.41.9-0.00.00.0-0.2-0.1-0.30.20.50.1-0.11.00.61.11.41.2
Lifetime Intake0.91.15.9-0.40.30.3-0.60.3-0.70.40.7-0.30.32.00.91.62.40.8
Liver weight, left1.82.97.01.6-1.6-1.61.7-1.5-2.3-1.62.51.5-1.52.6-1.00.41.21.7
Liver weight, right1.42.53.71.8-1.7-1.71.8-1.8-1.7-1.91.61.7-1.71.0-1.9-1.3-0.90.1
Locomotor activity0.20.30.8-0.40.30.3-0.70.40.60.6-0.9-0.40.4-0.60.3-0.2-0.0-0.8
Locomotor testing distance0.40.83.6-0.20.10.1-0.60.20.90.5-1.6-0.10.1-1.4-0.1-1.2-1.0-1.9
Locomotor testing rearing0.10.21.0-0.30.10.1-0.60.20.60.6-1.0-0.20.2-0.50.3-0.40.0-0.8
Locomotion in novel chamber1.41.82.5-1.61.41.4-1.41.41.61.6-1.6-1.51.5-1.41.00.5-0.0-1.4
Locomotion in novel chamber post-restriction0.30.50.9-0.70.70.7-0.80.70.90.8-0.9-0.80.8-0.80.60.2-0.1-0.6
Fecal boli incidents, locomotor time 11.01.46.00.7-1.0-1.00.7-1.0-0.0-0.7-0.10.8-0.8-1.1-1.4-1.7-1.9-2.5
Change in fecal boli incidents, locomotor task0.10.10.50.3-0.2-0.20.2-0.20.1-0.1-0.10.2-0.2-0.5-0.2-0.4-0.7-0.3
Time >=10cm from walls, locomotor time 11.61.78.70.8-0.7-0.70.9-0.70.5-1.0-0.70.8-0.8-2.0-1.3-2.1-3.0-0.7
Bouts of movement, locomotor time 10.50.62.50.2-0.5-0.50.2-0.50.3-0.1-0.60.3-0.3-1.0-0.5-1.2-1.2-1.6
Total resting periods, locomotor time 10.70.83.4-0.3-0.1-0.1-0.5-0.11.00.5-1.3-0.20.2-1.5-0.0-1.1-1.2-1.8
Rest time, locomotor task time 10.10.20.80.1-0.2-0.2-0.0-0.3-0.5-0.00.40.1-0.10.90.10.30.90.2
Distance moved, locomotor task time 10.40.62.60.6-0.7-0.70.7-0.70.0-0.7-0.20.6-0.6-0.9-1.0-1.3-1.6-0.3
Vertical activity count, locomotor time 10.10.20.5-0.40.50.5-0.40.50.60.3-0.2-0.50.5-0.60.50.4-0.20.7
Time >=10cm from walls, locomotor time 21.92.84.51.8-1.7-1.71.9-1.8-1.1-2.01.01.8-1.8-0.1-2.1-1.9-2.0-0.5
Bouts of movement, locomotor time 21.11.72.8-1.51.11.1-1.41.11.71.5-1.7-1.51.5-1.71.00.2-0.3-1.2
Total resting periods, locomotor time 21.11.93.0-1.61.31.3-1.51.21.71.6-1.7-1.61.6-1.71.00.3-0.3-1.5
Rest time, locomotor task time 20.10.10.3-0.40.10.1-0.40.10.30.6-0.2-0.40.4-0.20.50.10.20.5
Distance moved, locomotor task time 20.50.61.70.7-0.6-0.60.7-0.7-0.2-0.8-0.10.7-0.7-0.5-1.1-1.2-1.3-0.4
Vertical activity count, locomotor time 20.30.40.7-0.70.60.6-0.70.60.50.5-0.4-0.70.7-0.00.70.80.70.5
Light reinforcement 11.63.88.5-2.12.12.1-2.12.00.92.0-0.8-2.12.10.82.22.92.80.6
Light reinforcement 20.30.52.50.4-0.3-0.30.1-0.4-1.1-0.40.90.5-0.51.6-0.50.81.20.1
Bone: marrow area3.37.111.03.1-3.3-3.32.9-3.2-3.1-2.92.82.8-2.82.5-2.6-1.7-0.40.2
Bone: maximum diameter0.30.61.20.9-0.8-0.81.1-0.7-1.0-1.01.00.7-0.70.7-1.0-0.5-0.3-0.3
Bone: maximum force3.05.39.52.4-2.7-2.72.4-2.6-2.9-2.43.12.0-2.03.1-1.7-0.40.91.4
Bone: maximum moment2.44.28.12.1-2.4-2.42.1-2.3-2.6-2.02.81.7-1.72.8-1.4-0.21.01.4
Mean time between licks in bursts0.41.02.0-1.10.90.9-1.41.00.81.1-0.9-0.80.80.01.31.21.30.9
Mean num. licks in bursts0.20.31.10.2-0.3-0.30.3-0.5-0.5-0.10.8-0.10.11.00.20.60.91.1
Cd content in liver0.40.40.80.7-0.8-0.80.5-0.8-0.7-0.50.60.6-0.60.9-0.2-0.20.50.7
Co content in liver0.10.10.2-0.10.20.2-0.10.30.00.2-0.1-0.20.20.20.20.30.30.4
Cu content in liver0.60.71.00.9-0.9-0.90.9-0.9-0.8-0.80.70.9-0.90.5-1.0-0.9-0.5-0.7
Fe content in liver0.91.12.01.3-1.4-1.41.0-1.4-1.1-1.01.21.1-1.11.0-0.8-0.70.1-0.1
K content in liver0.20.21.30.1-0.1-0.10.1-0.00.2-0.1-0.20.1-0.1-0.8-0.4-0.8-1.2-0.6
Mg content in liver0.20.21.00.4-0.3-0.30.3-0.2-0.0-0.30.00.4-0.4-0.5-0.5-0.8-1.0-0.6
Mn content in liver1.92.14.1-1.51.41.4-1.71.32.01.6-2.0-1.41.4-2.01.30.2-0.5-0.3
Na content in liver0.10.10.50.2-0.2-0.20.3-0.2-0.1-0.30.00.1-0.1-0.3-0.5-0.6-0.6-0.7
Rb content in liver0.91.02.7-0.70.70.7-0.80.71.20.9-1.4-1.01.0-1.60.3-0.5-1.0-1.4
Se content in liver0.00.00.10.3-0.3-0.30.1-0.3-0.1-0.10.10.3-0.30.1-0.2-0.2-0.00.0
Sr content in liver1.81.54.31.0-1.1-1.10.9-1.1-1.5-0.91.80.9-0.92.1-0.20.51.31.8
Zn content in liver0.50.51.00.8-0.9-0.90.6-0.9-0.9-0.50.80.7-0.71.0-0.4-0.30.40.3
Bone: minimum diameter0.71.32.01.3-1.4-1.41.4-1.3-1.4-1.31.30.9-0.91.2-1.2-0.7-0.10.0
Time in familiar zone, hab. session 10.60.61.1-0.90.90.9-0.80.80.70.9-0.6-1.01.0-0.30.90.70.60.2
Time in novel zone, hab. session 11.41.42.61.2-0.9-0.91.6-0.8-1.3-1.61.31.3-1.30.7-1.6-0.9-1.0-0.5
Total zone transitions, hab. session 10.20.30.8-0.50.80.8-0.10.80.40.1-0.6-0.30.3-0.8-0.2-0.2-0.7-0.9
Total locomotion distance, hab. session 10.71.01.81.0-0.8-0.81.3-0.8-1.0-1.20.81.2-1.20.3-1.3-1.0-0.9-0.8
Locomotion velocity, hab. session 10.81.22.11.2-1.1-1.11.2-1.0-1.2-1.21.11.5-1.50.9-1.2-0.7-0.3-0.2
Time in familiar zone, hab. session 20.30.31.4-0.10.10.10.00.00.50.0-0.7-0.10.1-1.0-0.3-0.9-1.1-1.2
Time in novel zone, hab. session 20.50.51.70.3-0.3-0.30.4-0.2-0.8-0.41.10.4-0.41.3-0.00.91.01.3
Total zone transitions, hab. session 20.20.31.2-0.30.30.3-0.20.3-0.20.20.3-0.20.20.80.50.81.10.8
Total locomotion distance, hab. session 21.31.74.21.2-1.3-1.31.1-1.2-1.6-1.11.71.4-1.42.0-0.60.11.11.3
Locomotion velocity, hab. session 21.11.54.11.1-1.1-1.10.9-1.1-1.5-0.91.61.2-1.22.0-0.30.31.31.4
Novel to familiar place preference ratio5.45.810.12.6-2.4-2.42.5-2.4-3.0-2.53.22.8-2.83.1-1.8-0.20.71.7
Novelty place preference5.15.59.62.5-2.3-2.32.4-2.3-2.9-2.43.12.8-2.83.0-1.7-0.20.71.8
Time in novel zone, NPP test5.35.710.02.6-2.2-2.22.6-2.2-3.0-2.63.22.8-2.83.0-1.9-0.20.61.6
Total zone transitions, NPP test0.30.41.0-0.61.01.0-0.61.00.30.5-0.3-0.40.40.20.61.00.70.5
Total locomotion distance, NPP test0.40.51.30.8-0.6-0.60.7-0.5-0.9-0.80.81.1-1.10.8-0.7-0.20.00.2
Locomotion velocity, NPP test0.20.20.60.4-0.3-0.30.2-0.2-0.6-0.30.50.7-0.70.8-0.10.20.50.5
Intraocular pressure1.31.93.2-1.71.81.8-1.41.71.31.5-1.5-1.51.5-1.01.11.00.4-0.7
Delta distance traveled before/after self-admin0.70.81.1-1.00.90.9-1.00.91.01.0-0.9-1.11.1-0.80.90.70.2-0.6
Delta ambulatory time before/after self-admin0.60.71.2-0.90.80.8-0.90.80.91.1-1.0-1.01.0-0.60.80.50.4-0.7
Parametrial fat weight0.30.82.3-0.71.01.0-0.61.00.10.70.1-0.80.80.60.91.51.41.0
Pavlov. Cond. lever latency1.21.53.2-1.31.41.4-1.21.30.71.2-0.4-1.31.30.21.41.81.51.2
Pavlov. Cond. magazine entry latency1.82.35.11.5-1.4-1.41.4-1.3-0.8-1.60.41.4-1.4-0.5-2.0-2.3-2.3-1.7
Pavlov. Cond. change in total contacts1.01.03.00.9-1.1-1.10.7-1.0-0.2-0.8-0.10.8-0.8-0.6-1.1-1.7-1.5-1.3
Pavlov. Cond. index score1.62.03.81.5-1.6-1.61.4-1.5-0.9-1.40.61.4-1.4-0.1-1.7-1.9-1.7-1.2
Pavlov. Cond. latency score1.82.34.51.6-1.7-1.71.4-1.6-0.9-1.50.61.5-1.5-0.2-1.8-2.1-1.8-1.4
Pavlov. Cond. lever contacts0.91.12.41.1-1.3-1.31.0-1.2-0.6-1.00.41.0-1.0-0.2-1.2-1.6-1.2-1.0
Pavlov. Cond. magazine entry number1.72.23.5-1.71.61.6-1.51.61.11.6-0.8-1.51.5-0.11.81.91.61.1
Pavlov. Cond. intertrial magazine entries0.80.91.60.9-1.0-1.00.9-0.9-1.0-0.71.31.2-1.21.2-0.40.10.61.2
Pavlov. Cond. lever-magazine prob. diff.1.41.74.01.3-1.4-1.41.2-1.3-0.6-1.30.31.2-1.2-0.4-1.6-2.0-1.8-1.4
Pavlov. Cond. response bias1.41.72.91.4-1.4-1.41.4-1.3-1.0-1.40.71.3-1.30.0-1.6-1.7-1.5-1.0
Pavlov. Cond. lever latency0.50.72.40.5-0.4-0.40.9-0.5-1.2-0.81.40.2-0.21.6-0.30.60.91.3
Pavlov. Cond. magazine entry latency0.40.50.7-0.80.70.7-0.80.70.70.7-0.6-0.80.8-0.30.80.70.50.3
Pavlov. Cond. change in total contacts0.30.52.40.00.00.00.40.00.2-0.3-0.30.1-0.1-1.0-0.8-1.1-1.5-1.6
Pavlov. Cond. index score0.20.30.7-0.40.40.4-0.50.50.70.5-0.8-0.40.4-0.80.2-0.2-0.4-0.8
Pavlov. Cond. latency score0.10.20.5-0.40.40.4-0.40.40.50.4-0.7-0.30.3-0.60.2-0.1-0.3-0.7
Pavlov. Cond. lever contacts0.60.82.7-0.20.10.1-0.60.21.00.5-1.30.1-0.1-1.6-0.0-1.0-1.3-1.6
Pavlov. Cond. magazine entry number0.00.00.0-0.10.20.20.00.20.10.0-0.1-0.10.1-0.2-0.0-0.0-0.2-0.1
Pavlov. Cond. intertrial magazine entries0.20.31.1-0.40.20.2-0.80.30.80.8-1.1-0.20.2-0.80.5-0.2-0.0-0.6
Pavlov. Cond. lever-magazine prob. diff.0.30.41.0-0.50.50.5-0.50.50.80.5-0.9-0.40.4-1.00.2-0.3-0.6-1.0
Pavlov. Cond. response bias0.20.30.90.0-0.1-0.1-0.3-0.00.50.2-0.70.2-0.2-0.9-0.1-0.7-0.8-1.0
Time in closed arm before self-admin2.63.34.42.1-2.1-2.12.0-2.1-1.5-1.91.52.0-2.00.7-1.9-1.8-1.1-1.6
Time in closed arm after self-admin1.11.28.30.5-0.4-0.40.4-0.40.2-0.5-0.30.6-0.6-1.1-1.1-1.4-1.6-2.9
Time in open arm before self-admin6.77.310.9-3.13.13.1-3.13.01.92.9-1.4-3.03.0-0.23.23.32.71.7
Time in open arm after self-admin1.41.62.61.5-1.4-1.41.4-1.4-1.3-1.60.71.3-1.30.8-1.4-1.2-0.61.0
Bone: periosteal estimation2.24.66.82.4-2.6-2.62.5-2.4-2.6-2.42.52.1-2.12.2-2.1-1.2-0.20.2
Bone: periosteal perimeter1.83.24.72.0-2.1-2.12.1-2.0-2.2-2.02.11.6-1.61.8-1.8-1.1-0.20.1
Bone: post-yield work0.81.13.10.9-1.1-1.10.9-1.1-1.4-1.01.40.7-0.71.8-0.60.30.91.0
Progressive ratio test 1 active lever presses0.20.31.3-0.50.30.3-0.70.3-0.10.3-0.1-0.40.40.70.60.91.10.1
Progressive ratio test 1 breakpoint0.10.21.0-0.20.00.0-0.40.0-0.30.10.1-0.20.20.80.30.61.0-0.0
Progressive ratio test 1 inactive lever presses3.65.210.8-2.32.22.2-3.02.21.02.3-0.7-2.02.00.92.83.33.31.6
Progressive ratio test 2 active lever presses0.60.73.3-0.20.10.1-0.40.1-0.60.20.7-0.10.11.50.71.21.81.0
Progressive ratio test 2 breakpoint0.60.63.2-0.30.20.2-0.50.1-0.60.20.6-0.10.11.50.71.21.81.0
Progressive ratio test 2 inactive lever presses0.50.83.9-0.70.50.5-1.00.5-0.30.50.3-0.30.31.31.01.52.01.0
Incentive Sensitization - Responses0.40.61.20.7-0.9-0.90.4-1.0-0.7-0.70.81.0-1.00.8-0.2-0.20.41.1
Incentive Sensitization - Breakpoint0.40.51.30.6-0.8-0.80.3-0.9-0.7-0.60.90.9-0.90.9-0.1-0.00.51.1
Sum of active levers in priming session hrs 5-62.32.16.71.3-1.2-1.21.5-1.2-2.0-1.52.61.2-1.22.2-1.00.80.91.0
Progressive ratio0.20.30.6-0.50.50.5-0.20.60.50.4-0.0-0.60.6-0.40.70.40.00.8
Food seeking constrained by brief footshock0.40.52.00.6-0.6-0.60.7-0.60.1-0.7-0.10.8-0.8-0.9-0.7-1.0-1.4-0.4
Seeking ratio, punishment vs. effort0.71.12.11.1-1.2-1.20.7-1.2-0.5-0.9-0.01.3-1.3-0.2-1.2-1.4-1.2-0.8
Retroperitoneal fat weight0.41.88.1-0.70.80.8-1.10.7-0.30.90.5-0.80.81.91.42.22.91.6
Reaction time number correct0.61.12.1-1.11.21.2-0.91.20.71.0-0.4-1.41.4-0.01.31.31.00.8
Reaction time mean minus median1.43.65.92.1-1.9-1.91.7-2.0-2.3-1.82.32.4-2.42.4-1.4-0.30.61.0
Reaction time mean minus median AUC1.12.74.51.8-1.6-1.61.7-1.7-2.1-1.72.12.0-2.02.1-1.4-0.30.40.8
Reaction time num false alarms3.65.18.2-2.52.42.4-2.62.32.02.7-1.7-2.52.5-0.62.92.52.11.0
Reaction time num false alarms AUC3.75.89.7-2.62.52.5-2.72.51.92.8-1.5-2.62.6-0.33.12.92.51.4
Reaction time trials correct on left0.61.12.1-1.11.21.2-0.91.20.71.0-0.4-1.41.4-0.01.31.31.00.8
Reaction time trials on left0.51.01.9-1.01.11.1-0.81.10.60.9-0.3-1.41.40.11.31.31.10.9
Reaction time mean4.97.712.62.9-2.7-2.72.8-2.8-3.5-2.93.53.3-3.33.5-2.2-0.40.81.8
Reaction time mean AUC4.36.913.12.7-2.6-2.62.6-2.6-3.4-2.63.43.0-3.03.6-1.9-0.11.12.0
Median of all reaction times5.07.111.92.8-2.6-2.62.8-2.7-3.4-2.93.53.0-3.03.4-2.2-0.40.61.8
Reaction time omissions1.21.85.41.2-1.2-1.21.0-1.2-1.8-1.21.51.1-1.12.3-0.60.21.31.6
Reaction time false alarm rate1.72.44.0-1.71.51.5-1.91.51.42.0-1.2-1.51.5-0.42.01.71.50.6
Reaction time premature initiation rate1.42.07.9-0.30.30.3-0.20.41.50.4-1.6-0.40.4-2.8-0.5-1.6-2.8-2.4
Reaction time premature initiations1.01.75.8-1.01.11.1-0.71.11.70.9-1.5-1.31.3-2.40.4-0.4-1.7-1.5
Std. dev. reaction times3.26.08.92.8-2.7-2.72.4-2.7-2.9-2.52.93.0-3.02.7-2.1-0.80.31.1
Reaction time trials completed0.51.01.9-1.01.11.1-0.81.10.60.9-0.3-1.41.40.11.31.31.10.9
Reaction time trials AUC0.61.12.0-1.11.21.2-0.91.20.60.9-0.3-1.41.40.11.31.41.10.9
Run reversals in cocaine runway, females0.30.31.50.4-0.6-0.60.4-0.6-0.3-0.20.70.4-0.40.30.3-0.20.11.2
Run reversals in cocaine runway, males0.30.31.00.1-0.1-0.10.1-0.10.3-0.1-0.6-0.10.1-0.9-0.5-1.0-1.0-0.9
Latency to leave start box in cocaine runway4.55.28.6-2.72.92.9-2.62.92.22.4-2.4-2.52.5-1.42.21.61.00.2
Latency to leave start box in cocaine runway, F3.13.56.4-2.22.42.4-2.02.51.91.7-1.8-2.12.1-1.31.71.40.60.3
Latency to leave start box in cocaine runway, M2.52.34.3-1.81.71.7-1.81.71.61.8-2.1-1.61.6-1.21.40.50.4-0.2
Std. dev. time between licks in bursts1.11.52.7-1.51.41.4-1.51.51.41.3-1.7-1.01.0-1.01.20.80.4-0.0
Total sessions with >9 infusions1.21.43.8-1.31.21.2-1.31.20.31.2-0.2-1.11.10.81.41.71.90.5
Short access day 1 total inactive lever presses0.81.03.0-0.90.90.9-1.50.90.10.9-0.7-0.60.60.81.01.41.70.8
Short access day 10 total inactive lever presses0.41.03.1-1.21.01.0-1.81.10.61.1-1.2-0.80.80.11.00.91.20.8
Short access day 1 total infusions0.70.93.5-0.70.70.7-1.00.7-0.40.60.2-0.60.61.40.81.61.90.5
Short access day 10 total infusions0.81.15.20.2-0.3-0.3-0.2-0.4-1.20.11.30.3-0.32.30.21.42.20.1
Short access total infusions0.70.94.0-0.60.60.6-0.60.6-0.50.60.6-0.50.51.50.71.72.00.1
Short access day 1 locomotion0.50.62.6-0.60.50.5-0.80.5-0.20.60.1-0.50.51.00.91.31.60.7
Short access day 10 total locomotion1.01.83.1-1.61.41.4-1.81.40.91.6-1.2-1.61.6-0.11.41.21.3-0.8
Short access total locomotion1.82.24.9-1.61.51.5-1.71.40.61.7-0.5-1.61.60.71.92.02.20.7
One hour access (0.3 mA shock)0.50.53.30.0-0.2-0.2-0.4-0.2-0.90.00.30.2-0.21.80.10.71.8-0.2
Compulsive drug intake1.01.13.1-1.01.01.0-1.31.01.51.1-1.8-0.90.9-1.60.8-0.1-0.50.4
One hour access (shock baseline)0.91.36.50.7-0.8-0.80.6-0.8-1.7-0.61.40.7-0.72.6-0.30.61.9-0.1
Social response proportion2.02.33.51.6-1.6-1.61.7-1.7-1.9-1.61.61.6-1.61.6-1.6-1.0-0.0-0.6
Social responses0.30.41.90.5-0.4-0.40.5-0.4-1.1-0.70.80.4-0.41.4-0.70.10.8-0.4
Social time1.11.52.71.3-0.9-0.91.6-0.9-1.4-1.61.21.4-1.40.7-1.6-1.0-0.9-0.8
Soleus weight0.10.20.90.2-0.3-0.3-0.0-0.40.20.0-0.30.4-0.4-0.4-0.1-0.6-0.5-0.9
Bone: stiffness2.64.310.41.9-2.1-2.11.9-2.1-2.6-1.92.91.6-1.63.2-1.00.41.72.2
Tibialis anterior weight0.92.94.5-1.91.71.7-2.11.81.92.0-1.8-2.12.1-1.22.01.30.90.3
Time to tail flick, vehicle, before self-admin0.10.20.90.4-0.4-0.40.4-0.5-0.3-0.30.90.2-0.20.2-0.10.4-0.00.1
Time to tail flick, vehicle, after self-admin0.40.51.30.7-0.7-0.70.7-0.7-0.7-0.71.10.8-0.80.6-0.30.30.11.2
Time to tail flick, test, before self-admin0.80.81.6-1.10.80.8-1.20.90.91.3-0.5-1.01.0-0.41.21.00.70.2
Time to tail flick, test, after self-admin0.80.91.5-1.11.01.0-1.21.01.11.1-1.0-0.90.9-0.71.10.50.30.3
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.20.30.3-0.30.30.10.3-0.5-0.10.10.10.30.20.40.6
Delta time to tail flick, test, before/after SA0.10.10.40.10.00.00.10.00.1-0.3-0.50.2-0.2-0.5-0.3-0.6-0.7-0.3
Tibia length3.910.817.63.6-3.6-3.63.6-3.6-4.1-3.74.23.2-3.23.9-2.9-1.00.41.7
Ambulatory time before self-admin1.21.83.51.4-1.2-1.21.6-1.2-1.9-1.61.71.5-1.51.9-1.3-0.30.40.4
Ambulatory time after self-admin0.10.20.7-0.30.50.5-0.10.50.00.2-0.1-0.40.40.20.10.50.4-0.8
Bone: tissue strength1.21.23.60.8-0.9-0.90.7-0.9-1.3-0.71.50.8-0.81.9-0.20.71.41.6
Total heroin consumption1.31.55.80.10.20.20.60.2-1.4-0.52.20.1-0.12.40.12.02.11.0
Bone: trabecular number1.01.73.71.6-1.9-1.91.0-1.9-1.3-1.21.21.1-1.11.2-0.9-0.70.10.5
Bone: trabecular spacing0.40.51.5-0.50.80.8-0.10.80.60.2-0.7-0.10.1-1.1-0.2-0.5-1.0-1.2
Bone: trabecular thickness0.70.91.81.1-1.3-1.30.9-1.3-0.9-0.81.00.8-0.80.8-0.7-0.6-0.10.4
Bone: trabecular tissue density0.30.41.8-0.0-0.1-0.1-0.3-0.1-0.10.40.3-0.10.10.80.70.81.41.3
Water consumed over 24 hours0.40.61.4-0.70.50.5-1.20.40.71.0-0.9-0.70.7-0.11.10.81.00.5
Number of responses in last shaping day0.70.71.6-0.71.11.1-0.81.20.30.8-0.2-0.80.80.41.01.01.30.3