Hub : Genes

Slc38a11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Slc38a11 0.07 0.05 5.5e-04 0.03 0.02 0.03 0.03 9.8e-05 2.3e-03 3.9e-04 2.8e-04
2 RMTg isoform ratio XM_063284118.1 0.13 0.07 5.1e-03 0.04 0.03 0.06 0.04 3.7e-02 4.2e-02 8.5e-03 3.5e-02
3 IL isoform ratio XM_063284118.1 0.15 0.08 8.7e-03 0.07 0.08 0.05 0.07 9.0e-03 5.5e-03 2.7e-02 9.8e-03
4 Adipose isoform ratio XM_063284120.1 0.18 0.07 0.0e+00 0.08 0.14 0.14 0.14 2.4e-09 1.6e-15 3.6e-15 2.4e-15
5 Adipose gene expression Slc38a11 0.2 0.07 0.0e+00 0.09 0.16 0.15 0.15 1.1e-09 2.3e-17 1.3e-16 1.5e-16
6 NAcc gene expression Slc38a11 0.03 0.01 1.6e-03 0.01 0.02 0.02 0.02 4.4e-03 1.3e-04 7.8e-04 1.6e-03
7 Adipose alternative polyA XM_063284120.1 0.07 0.04 6.6e-08 0.01 0.06 0.06 0.04 2.7e-02 1.0e-06 6.8e-07 1.1e-05
8 pVTA isoform ratio XM_063284118.1 0.04 0.02 6.7e-03 0.01 0.01 0.01 0.02 3.1e-02 1.9e-02 4.4e-02 1.5e-02
9 IL gene expression Slc38a11 0.28 0.14 6.1e-04 0.11 0.12 0.18 0.17 1.3e-03 8.6e-04 3.6e-05 6.8e-05
10 Adipose alternative polyA XM_063284118.1 0.07 0.04 2.4e-07 0.02 0.05 0.04 0.04 3.4e-03 1.6e-06 1.7e-05 3.2e-05
11 Brain gene expression Slc38a11 0.43 0.1 0.0e+00 0.31 0.29 0.33 0.06 1.1e-29 4.4e-27 1.0e-31 1.5e-06
12 pVTA gene expression Slc38a11 0.07 0.04 8.4e-04 0.01 0.02 0.02 0.01 9.5e-02 1.3e-02 9.9e-03 4.9e-02
13 LHb gene expression Slc38a11 0.14 0.08 6.7e-03 0.04 0.08 0.04 0.05 3.2e-02 5.4e-03 4.1e-02 3.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.81.64.9-0.91.0-0.30.2-0.2-1.7-0.70.42.2-0.62.21.5-1.5
Area under the delay curve0.50.81.5-0.50.6-0.9-1.01.00.71.2-1.2-1.11.2-0.3-0.50.9
BMI with tail0.20.71.7-0.7-0.40.91.2-1.3-0.7-0.40.40.1-1.30.70.9-0.5
BMI without tail0.10.31.20.1-0.40.1-0.20.20.70.8-0.2-1.10.3-0.8-0.60.7
Body weight0.52.44.30.9-1.71.61.8-1.8-1.3-1.11.90.9-2.10.81.9-1.6
Weight adjusted by age0.20.62.9-0.71.3-0.5-0.20.1-0.7-0.5-0.51.70.01.1-0.0-0.3
Bone surface0.71.43.40.20.30.20.7-0.7-1.7-1.00.81.8-1.01.81.3-1.8
Bone volume0.51.03.0-0.20.40.30.6-0.6-1.3-0.80.91.7-0.81.51.3-1.3
Breakpoint value in progressive ratio session1.22.14.9-2.01.7-2.1-1.71.5-0.51.4-2.2-1.31.40.80.30.2
Number of licking bursts0.20.72.0-0.10.4-0.20.1-0.1-1.3-0.60.90.8-0.61.11.3-1.4
Context. condit. distance diff. score0.30.41.2-0.00.3-0.4-0.80.70.61.11.0-0.80.6-0.30.20.5
Locomotion velocity, session 10.10.20.60.20.40.10.4-0.50.3-0.0-0.8-0.2-0.20.3-0.60.4
Locomotion distance, session 10.10.10.90.10.2-0.2-0.10.1-0.2-0.0-0.50.60.11.0-0.0-0.2
Locomotion velocity, session 20.50.61.9-0.90.8-0.6-0.60.60.70.4-1.4-0.00.9-0.1-1.01.0
Locomotion distance, session 20.71.02.31.1-1.51.01.1-0.9-0.7-1.20.51.2-1.00.90.3-1.0
Locomotion velocity, session 30.20.31.2-0.60.8-0.4-0.10.0-0.6-0.1-0.30.7-0.01.10.3-0.3
Locomotion distance, session 30.20.31.00.20.3-0.7-0.20.3-0.80.0-0.30.40.11.00.3-0.9
Stereotopy head waving bouts, day 32.42.96.71.1-2.21.41.4-1.2-1.5-1.82.61.3-1.81.01.9-2.1
Stereotopy head waving duration, day 31.31.64.70.8-1.71.31.1-1.0-0.7-1.32.20.9-1.40.31.3-1.1
Locomotion velocity, session 70.20.21.00.8-0.00.10.00.10.50.4-0.5-0.70.3-0.4-1.00.3
Locomotion distance, session 70.20.21.11.0-0.70.50.5-0.4-0.2-0.40.10.2-0.4-0.2-0.2-0.5
Stereotopy head waving bouts, day 71.01.13.9-0.2-0.3-0.6-0.30.4-1.8-0.30.70.9-0.31.71.6-2.0
Stereotopy head waving duration, day 70.70.83.40.2-0.1-0.6-0.20.3-1.6-0.10.70.6-0.21.31.3-1.9
Locomotion velocity, session 80.40.51.10.30.3-0.3-0.70.61.00.7-0.4-0.90.8-0.7-0.90.9
Locomotion distance, session 80.20.31.50.2-0.30.0-0.20.1-0.30.31.20.2-0.10.70.9-0.6
Degree of sensitization distance0.10.20.70.0-0.60.4-0.00.00.2-0.00.8-0.0-0.2-0.70.50.1
Degree of sensitization stereotypy1.21.33.9-1.21.0-1.2-0.70.7-1.70.1-0.30.90.22.01.5-1.5
Conditioned locomotion0.30.41.0-0.0-0.1-0.4-0.40.6-0.9-0.30.50.90.10.90.9-1.0
Cocaine response after cond. corrected0.30.41.8-1.41.1-0.6-0.60.5-0.30.5-0.30.10.30.60.80.2
Cocaine response after cond. not corrected0.00.10.30.0-0.30.1-0.20.30.00.30.5-0.20.10.00.5-0.0
Cocaine response before conditioning1.21.56.32.5-2.41.30.7-0.50.3-0.31.5-0.4-0.5-0.9-0.2-0.7
Saline control response0.50.71.1-0.70.60.80.8-0.9-0.3-1.01.01.1-0.91.01.10.0
Bone: connectivity density1.62.67.5-0.91.1-0.50.3-0.4-2.5-1.10.42.5-0.92.72.1-2.2
Bone: cortical apparent density1.42.24.8-0.50.20.41.3-1.3-2.2-1.60.52.1-1.71.81.7-1.9
Bone: cortical area1.62.66.42.3-2.52.41.8-1.80.9-1.22.0-0.1-1.5-1.2-0.20.1
Bone: cortical porosity0.40.51.21.0-1.0-0.4-0.60.70.11.10.4-1.10.6-0.50.0-0.3
Bone: cortical porosity0.40.52.31.5-1.10.40.1-0.10.40.60.8-0.80.0-0.7-0.3-0.1
Bone: cortical thickness1.11.94.20.9-1.82.11.8-1.80.0-1.61.70.8-1.8-0.20.7-0.3
Bone: cortical thickness1.01.23.51.3-1.91.51.0-0.90.3-1.01.80.2-1.0-0.80.6-0.2
Bone: cortical tissue density1.42.35.2-0.60.30.31.3-1.3-2.3-1.60.42.2-1.71.91.8-1.9
Condit. Reinf. active minus inactive responses1.82.14.61.4-1.60.91.3-1.0-1.6-1.61.41.5-1.51.11.4-2.1
Condit. Reinf. active-inactive response ratio0.60.61.40.8-0.80.60.7-0.6-0.8-0.80.80.6-0.80.60.8-1.2
Condit. Reinf. active responses1.41.84.62.1-1.81.11.4-1.1-0.9-1.41.51.0-1.30.30.6-1.7
Condit. Reinf. inactive responses0.60.83.92.0-1.30.91.0-0.8-0.1-0.80.90.2-0.7-0.5-0.4-0.7
Incentive salience index mean2.12.66.31.5-1.80.91.5-1.2-2.0-1.81.31.7-1.71.11.6-2.5
Condit. Reinf. lever presses0.71.01.60.7-1.10.81.1-1.1-1.1-1.21.01.0-1.30.40.9-1.2
Condit. Reinf. active minus inactive responses1.82.76.22.3-2.02.52.0-1.90.5-1.62.41.0-1.6-0.30.0-0.2
Condit. Reinf. active-inactive response ratio0.71.12.81.5-1.11.71.3-1.20.6-1.11.20.7-1.0-0.4-0.50.2
Condit. Reinf. active responses2.63.78.62.5-2.32.72.3-2.20.1-1.92.91.2-2.1-0.30.6-0.7
Condit. Reinf. inactive responses0.60.94.20.9-1.31.20.9-0.9-0.0-0.72.00.4-0.9-0.20.8-0.3
Condit. Reinf. lever presses2.94.210.82.7-2.62.92.3-2.10.1-2.03.31.4-2.1-0.30.7-0.8
Condit. Reinf. lever reinforcers received2.43.47.32.2-1.92.72.3-2.20.2-2.02.71.4-2.0-0.20.4-0.4
Conditioned reinforcement - actives0.20.82.61.6-1.60.70.5-0.40.5-0.30.6-1.4-0.3-0.9-0.2-0.0
Conditioned reinforcement - inactives0.10.20.90.8-0.4-0.2-0.20.20.10.4-0.4-0.90.2-0.3-0.4-0.3
Conditioned locomotion0.71.04.31.0-1.00.70.1-0.21.40.20.4-2.10.1-1.5-0.31.1
Patch foraging indifference point 0 sec1.43.810.1-0.90.90.10.9-0.9-2.9-1.51.82.4-1.72.63.2-2.6
Patch foraging indifference point AUC0.81.97.11.3-0.2-0.3-0.70.91.91.1-1.1-0.91.5-1.8-2.71.4
Delay disc. indifference point, 0s delay0.50.61.50.8-0.30.81.2-1.2-0.6-1.00.40.2-1.10.40.4-0.6
Delay disc. indifference point, 16s delay0.40.61.5-0.30.3-1.2-1.11.2-0.00.7-1.1-0.91.1-0.0-0.0-0.1
Delay disc. indifference point, 2s delay0.40.41.50.40.10.30.9-0.9-0.2-0.8-1.20.4-0.50.6-0.8-0.1
Delay disc. indifference point, 24s delay1.01.73.6-0.30.6-1.7-1.91.90.51.8-1.3-1.31.9-0.5-0.50.5
Delay disc. indifference point, 4s delay0.50.61.8-0.70.9-0.4-0.30.20.61.0-1.4-0.80.70.3-0.51.0
Delay disc. indifference point, 8s delay0.71.22.5-0.70.5-0.9-1.31.31.11.6-1.1-1.21.5-0.5-0.61.2
Indifference point function ln k0.41.22.60.1-0.20.61.0-1.0-1.5-1.00.90.9-1.41.31.6-1.5
Indifference point function log k0.41.22.60.1-0.20.61.0-1.0-1.5-1.00.90.9-1.41.31.6-1.5
Patch foraging total patch changes 0 sec1.33.910.1-1.31.4-0.10.6-0.7-2.9-1.31.52.5-1.52.93.2-2.5
Patch foraging total patch changes 12 sec0.20.21.21.1-0.50.40.4-0.3-0.1-0.50.30.3-0.3-0.2-0.2-0.5
Patch foraging total patch changes 18 sec0.10.20.70.8-0.2-0.1-0.20.4-0.3-0.10.40.40.20.0-0.2-0.8
Patch foraging total patch changes 24 sec0.31.23.90.5-0.81.41.1-1.0-0.3-1.42.01.3-1.20.00.9-0.6
Patch foraging total patch changes 6 sec0.50.92.2-0.71.1-0.7-0.20.3-1.5-0.30.21.1-0.21.41.2-1.4
Patch foraging time to switch 0 sec0.10.21.2-1.10.0-0.5-0.40.3-0.4-0.1-0.3-0.4-0.00.20.9-0.0
Patch foraging water rate 0 sec0.41.33.61.9-1.71.11.2-1.0-0.8-0.91.30.5-1.20.20.6-1.5
Patch foraging water rate 12 sec0.41.53.51.9-1.61.81.7-1.60.1-1.21.00.5-1.4-0.4-0.5-0.3
Patch foraging water rate 18 sec0.61.43.51.4-1.21.91.6-1.71.0-1.00.7-0.2-1.1-0.8-0.80.9
Patch foraging water rate 24 sec0.10.10.40.4-0.00.60.4-0.40.3-0.20.30.3-0.30.0-0.40.3
Patch foraging water rate 6 sec0.81.23.31.8-1.41.51.4-1.40.2-0.91.3-0.3-1.2-0.5-0.2-0.3
Seeking ratio, delayed vs. immediate footshock0.10.21.00.7-1.00.50.4-0.3-0.2-0.40.5-0.1-0.4-0.20.3-0.4
Distance traveled before self-admin0.61.23.11.5-1.81.41.2-1.20.1-0.91.5-0.5-1.2-0.50.7-0.3
Distance traveled after self-admin0.91.65.22.3-2.01.61.4-1.30.6-1.11.0-0.9-1.0-1.1-0.6-0.0
Extensor digitorum longus weight0.51.94.60.8-1.22.12.1-2.0-0.0-1.91.01.2-1.8-0.1-0.1-0.2
Bone: elastic displacement0.10.20.6-0.70.40.50.5-0.60.1-0.40.20.4-0.50.2-0.10.5
Bone: elastic work1.62.15.1-0.80.12.01.8-2.10.0-1.91.62.3-1.80.80.40.5
Bone: endosteal estimation1.22.97.21.9-0.90.4-0.70.82.71.5-0.3-2.31.4-2.4-2.42.0
Bone: endosteal perimeter0.92.38.42.9-1.61.50.7-0.52.10.20.5-1.20.2-1.9-2.21.2
Epididymis fat weight2.010.133.9-5.85.5-3.9-3.12.8-1.62.2-3.01.22.23.01.60.3
Delta time in closed arm before/after self-admin0.10.10.4-0.60.40.00.1-0.2-0.3-0.2-0.10.6-0.20.60.5-0.1
Delta time in open arm before/after self-admin0.40.51.20.5-0.51.11.0-1.00.1-1.01.10.2-0.9-0.40.20.1
Diff in mean of infusions in LGA sessions2.95.114.2-3.83.3-3.2-2.21.9-1.81.7-2.0-0.51.42.61.9-0.7
Delay discount exponential model param1.01.42.40.6-0.71.01.3-1.3-1.0-1.51.61.4-1.50.50.8-1.2
Extinction: sum of active levers before priming0.20.30.70.4-0.10.40.8-0.8-0.6-0.70.4-0.1-0.80.30.8-0.5
Active lever presses in extinction session 63.13.26.60.6-0.70.71.8-1.8-2.5-2.10.51.1-2.22.22.1-2.6
Bone: final force2.33.79.22.5-2.41.60.5-0.43.00.30.3-1.80.5-2.9-2.72.2
Bone: final moment2.64.210.92.5-2.41.90.6-0.53.30.30.3-1.80.5-3.1-2.92.5
Food consumed during 24 hour testing period0.61.33.00.8-1.01.31.3-1.2-0.6-1.61.70.9-1.40.30.9-0.9
Glucose0.60.92.61.3-1.01.20.9-0.81.3-0.2-0.4-0.5-0.2-1.0-1.61.0
Heart weight0.60.93.40.4-0.3-0.10.5-0.3-1.6-0.90.70.8-0.71.21.2-1.8
Delay discount hyperbolic model param1.01.32.80.6-0.81.01.1-1.1-1.0-1.41.71.2-1.40.40.9-1.3
Intermittent access intake day 1-15 change0.21.02.01.4-1.11.41.2-1.01.1-0.9-0.3-0.1-0.4-1.1-1.40.9
Intermittent access intake escalation0.10.61.51.2-0.71.00.9-0.80.8-0.7-0.40.1-0.3-0.8-1.20.7
Intermittent access intake escalation 20.50.81.60.9-0.71.21.1-1.00.8-1.0-0.20.5-0.5-0.7-1.30.7
Intermitt. access day 1 inactive lever presses0.10.71.7-0.60.2-0.00.3-0.3-1.3-0.40.90.9-0.71.01.3-1.2
Intermitt. access day 15 inactive lever presses0.00.20.80.6-0.50.70.5-0.40.1-0.40.90.3-0.4-0.20.1-0.1
Intermitt. access escalation Index0.20.82.8-0.70.40.10.3-0.3-1.2-0.30.81.7-0.71.11.2-1.0
Intermittent access day 1 total infusions0.10.41.30.2-0.1-0.7-0.90.90.21.0-0.4-1.10.8-0.50.10.1
Intermittent access day 15 total infusions0.30.71.90.9-0.6-0.2-0.50.61.00.5-0.9-1.40.8-1.2-0.90.7
Intermittent access terminal intake (last 3 days)0.10.20.91.0-0.80.40.3-0.20.4-0.4-0.2-0.4-0.1-0.6-0.40.1
Intermittent access total infusions0.40.51.70.6-0.4-0.3-0.60.70.70.7-0.5-1.30.7-0.9-0.40.5
Intermittent access day 1 locomotion0.50.92.9-0.60.3-0.9-1.21.10.51.30.2-1.70.9-0.80.60.6
Intermittent access day 15 total locomotion0.20.71.61.0-0.90.80.7-0.70.9-0.10.1-1.3-0.4-1.3-0.40.8
Intermittent access total locomotion0.30.31.20.7-0.70.40.3-0.40.50.00.4-1.1-0.3-0.90.10.4
Intermittent access standard deviation0.52.56.71.7-1.81.20.6-0.52.2-0.4-0.7-2.10.2-2.6-2.01.8
Left kidney weight0.21.95.52.4-1.91.61.3-1.21.3-0.10.0-1.0-0.6-1.6-1.80.8
Right kidney weight0.64.111.53.4-2.62.82.8-2.70.7-1.51.3-0.2-2.1-1.3-1.2-0.1
Cocaine induced anxiety0.41.15.3-2.31.6-0.5-0.50.3-0.50.4-0.21.50.21.41.10.2
Post-drug Anxiety0.20.21.0-0.00.10.20.0-0.0-0.30.00.71.0-0.20.30.7-0.4
Baseline Anxiety1.11.96.12.5-1.90.81.0-0.8-1.3-1.21.70.4-1.3-0.20.8-2.1
Tail length0.21.37.12.7-1.90.3-0.40.60.80.50.7-1.00.6-1.6-0.8-0.1
Length with tail0.41.85.22.3-2.11.11.0-0.9-0.9-0.91.80.7-1.20.11.1-1.7
Length without tail0.73.96.61.5-2.02.02.3-2.4-1.6-1.92.11.6-2.61.11.9-2.1
Times rat made contact with spout0.30.31.9-1.40.60.3-0.0-0.00.3-0.40.20.7-0.00.30.30.7
Lifetime Intake0.30.42.30.6-0.6-0.4-0.60.60.40.6-0.6-1.50.6-0.7-0.00.2
Liver weight, left0.30.51.10.3-0.81.00.9-1.0-0.2-0.60.80.5-1.10.10.8-0.3
Liver weight, right0.40.71.80.6-1.11.31.1-1.20.7-0.50.6-0.2-0.9-1.0-0.40.5
Locomotor activity1.72.66.31.5-1.82.12.1-2.0-0.5-2.51.31.6-2.00.40.6-0.9
Locomotor testing distance1.53.87.52.2-1.92.72.7-2.6-0.2-2.71.81.5-2.4-0.10.2-0.7
Locomotor testing rearing1.86.614.33.3-2.83.83.5-3.30.5-3.42.41.3-2.9-1.2-0.4-0.2
Locomotion in novel chamber0.40.61.90.0-0.6-0.6-0.90.80.51.1-0.4-1.40.8-1.0-0.10.4
Locomotion in novel chamber post-restriction0.51.54.4-0.5-0.50.91.0-1.2-1.0-1.51.91.4-1.50.52.1-0.8
Fecal boli incidents, locomotor time 10.41.02.9-0.70.8-1.7-1.41.6-1.20.6-0.30.30.80.40.7-1.2
Change in fecal boli incidents, locomotor task0.30.41.00.6-1.00.70.3-0.31.0-0.1-0.1-0.50.0-0.8-0.60.8
Time >=10cm from walls, locomotor time 10.10.20.8-0.1-0.90.40.1-0.1-0.1-0.30.80.2-0.30.00.3-0.2
Bouts of movement, locomotor time 12.73.511.8-3.42.8-2.5-2.32.0-1.11.6-0.60.21.31.21.7-0.2
Total resting periods, locomotor time 13.13.511.3-3.42.8-2.6-2.42.1-0.91.7-0.8-0.11.51.01.6-0.1
Rest time, locomotor task time 11.62.76.3-2.32.2-2.3-2.52.3-0.31.8-0.30.01.80.20.60.2
Distance moved, locomotor task time 11.44.110.52.0-2.13.03.2-3.1-0.2-2.41.10.9-2.60.20.1-0.5
Vertical activity count, locomotor time 10.21.12.90.5-0.81.71.5-1.61.1-0.8-0.2-0.1-0.9-0.5-1.01.2
Time >=10cm from walls, locomotor time 20.51.32.81.3-1.71.40.6-0.61.6-0.10.8-1.1-0.3-1.7-1.01.2
Bouts of movement, locomotor time 20.41.35.5-2.41.1-1.6-1.61.4-0.51.1-0.3-0.20.90.40.90.0
Total resting periods, locomotor time 20.52.08.0-2.81.7-2.0-1.81.5-1.01.0-0.40.30.91.11.3-0.4
Rest time, locomotor task time 21.01.63.1-1.61.4-1.3-1.11.0-1.7-0.20.71.70.21.41.8-1.4
Distance moved, locomotor task time 22.43.29.01.9-2.03.02.7-2.71.1-1.41.3-0.2-2.0-0.8-0.50.9
Vertical activity count, locomotor time 20.30.82.50.10.21.01.0-1.11.4-0.0-0.6-0.6-0.3-0.5-1.41.6
Light reinforcement 10.00.20.50.40.40.60.5-0.60.7-0.10.4-0.1-0.2-0.3-0.40.7
Light reinforcement 20.40.92.3-0.11.3-0.4-0.70.61.31.2-0.6-0.61.1-0.5-1.21.5
Bone: marrow area1.02.56.11.9-0.80.3-0.70.82.51.4-0.3-2.11.4-2.2-2.21.8
Bone: maximum diameter0.71.54.82.2-1.91.71.1-1.10.7-0.61.8-0.4-0.9-0.8-0.1-0.1
Bone: maximum force1.83.57.82.7-2.42.11.0-1.02.8-0.10.8-1.4-0.1-2.6-2.32.0
Bone: maximum moment2.24.29.52.7-2.52.31.2-1.13.1-0.10.8-1.5-0.1-2.9-2.62.3
Mean time between licks in bursts0.31.74.31.7-1.12.11.7-1.70.8-1.01.50.3-1.3-1.0-0.60.5
Mean num. licks in bursts0.20.52.5-0.7-0.10.60.2-0.31.20.0-0.60.00.2-0.6-0.91.6
Cd content in liver0.40.41.1-0.70.4-0.9-1.01.10.10.4-0.6-0.10.90.3-0.30.3
Co content in liver0.91.02.71.4-1.61.31.1-0.9-0.1-1.41.10.8-0.9-0.00.3-0.5
Cu content in liver1.92.24.80.70.2-1.0-1.21.31.61.8-1.8-2.01.8-1.3-2.21.4
Fe content in liver0.40.51.5-1.01.2-1.0-0.30.2-0.80.3-1.00.00.21.10.4-0.3
K content in liver0.80.82.31.3-0.10.1-0.10.11.20.7-0.5-1.00.6-1.3-1.50.9
Mg content in liver0.90.93.01.30.10.0-0.20.21.30.8-0.5-1.30.7-1.3-1.71.0
Mn content in liver1.71.94.32.1-1.11.31.7-1.5-1.0-1.71.11.4-1.50.80.3-1.5
Na content in liver1.01.14.82.2-1.51.00.7-0.81.10.30.6-1.4-0.3-1.1-0.80.5
Rb content in liver0.40.52.61.6-1.00.60.5-0.2-0.2-0.60.7-0.0-0.3-0.4-0.1-0.8
Se content in liver0.60.71.5-1.20.2-0.20.00.0-1.2-0.80.31.2-0.41.01.2-0.9
Sr content in liver0.70.61.00.5-1.01.01.0-0.9-0.3-1.00.70.7-1.00.30.3-0.5
Zn content in liver0.60.72.0-0.5-0.3-0.2-0.90.81.10.80.4-1.40.8-1.4-0.11.0
Bone: minimum diameter0.61.22.91.7-1.11.30.7-0.71.70.30.6-1.0-0.2-1.4-1.31.2
Time in familiar zone, hab. session 10.60.71.61.0-0.6-0.4-0.81.00.60.9-0.3-1.21.1-0.7-1.00.1
Time in novel zone, hab. session 10.50.61.3-1.11.20.40.8-1.1-0.4-0.5-0.21.1-0.90.80.40.3
Total zone transitions, hab. session 11.11.54.41.1-1.82.11.3-1.41.1-0.71.70.5-1.0-0.6-0.00.8
Total locomotion distance, hab. session 11.52.15.62.0-1.82.41.8-1.91.0-0.91.30.7-1.3-0.4-0.90.6
Locomotion velocity, hab. session 10.91.33.21.6-1.51.81.1-1.21.5-0.31.00.0-0.6-0.7-1.21.1
Time in familiar zone, hab. session 21.01.23.1-1.71.7-0.7-1.10.80.81.70.5-0.70.9-0.00.31.4
Time in novel zone, hab. session 20.60.61.91.4-1.10.30.7-0.4-0.8-1.2-0.40.5-0.60.2-0.1-1.3
Total zone transitions, hab. session 20.60.81.60.5-1.11.10.9-1.0-0.3-0.81.21.0-1.00.71.0-0.5
Total locomotion distance, hab. session 20.50.72.30.1-0.00.50.9-0.9-0.8-0.70.41.3-0.91.50.6-0.7
Locomotion velocity, hab. session 20.40.51.60.10.00.60.9-1.0-0.5-0.60.21.1-0.81.30.3-0.4
Novel to familiar place preference ratio0.30.41.9-0.3-0.60.20.2-0.2-0.8-0.40.80.3-0.60.61.4-0.8
Novelty place preference0.20.31.7-0.6-0.3-0.0-0.10.0-0.7-0.20.50.1-0.30.61.3-0.6
Time in novel zone, NPP test0.20.21.6-0.7-0.2-0.1-0.20.1-0.5-0.00.5-0.1-0.20.41.3-0.4
Total zone transitions, NPP test0.20.41.2-0.1-0.60.30.1-0.1-0.4-0.11.10.8-0.30.81.1-0.5
Total locomotion distance, NPP test0.50.61.00.9-0.81.00.9-0.9-0.3-0.61.01.0-0.80.90.2-0.5
Locomotion velocity, NPP test0.71.01.61.2-1.11.21.3-1.2-0.3-0.81.11.1-1.10.90.1-0.7
Intraocular pressure0.20.30.80.1-0.80.90.4-0.40.5-0.50.8-0.1-0.4-0.70.20.4
Delta distance traveled before/after self-admin0.20.21.00.40.3-0.00.3-0.1-0.1-0.3-1.00.00.10.2-1.0-0.1
Delta ambulatory time before/after self-admin0.30.51.71.3-0.80.70.8-0.60.2-0.8-0.4-0.0-0.4-0.5-1.2-0.1
Parametrial fat weight1.33.09.6-3.03.1-1.3-1.41.11.01.6-1.90.41.50.4-0.92.2
Pavlov. Cond. lever latency2.83.56.3-0.11.5-1.0-1.51.32.32.3-1.7-2.42.0-1.7-2.42.5
Pavlov. Cond. magazine entry latency0.10.20.70.2-0.6-0.4-0.20.3-0.6-0.30.00.30.10.30.2-0.8
Pavlov. Cond. change in total contacts0.91.03.40.5-1.1-0.00.6-0.4-1.6-1.10.01.0-0.81.20.8-1.8
Pavlov. Cond. index score1.51.94.80.8-1.50.61.1-1.0-1.8-1.71.11.5-1.41.11.4-2.2
Pavlov. Cond. latency score2.12.76.10.7-1.70.81.3-1.1-2.1-2.01.51.8-1.71.41.9-2.5
Pavlov. Cond. lever contacts2.63.16.30.2-1.20.81.4-1.3-2.3-2.11.52.2-1.91.72.3-2.5
Pavlov. Cond. magazine entry number0.40.52.2-0.50.50.4-0.20.11.30.80.5-0.70.3-0.8-0.21.5
Pavlov. Cond. intertrial magazine entries0.70.82.91.7-1.41.10.6-0.50.7-0.31.4-0.1-0.4-0.8-0.40.2
Pavlov. Cond. lever-magazine prob. diff.1.11.33.40.7-1.40.50.9-0.8-1.5-1.40.91.1-1.20.81.2-1.8
Pavlov. Cond. response bias0.60.82.90.4-0.6-0.30.4-0.2-1.5-1.0-0.21.1-0.51.00.6-1.7
Pavlov. Cond. lever latency1.82.54.7-1.71.9-1.9-1.71.60.71.9-2.2-1.41.8-0.2-1.21.3
Pavlov. Cond. magazine entry latency0.40.51.3-0.2-0.3-0.8-1.11.2-0.30.90.1-0.90.7-0.11.0-0.5
Pavlov. Cond. change in total contacts0.20.52.01.4-1.10.50.5-0.4-0.6-0.50.70.3-0.60.20.4-1.1
Pavlov. Cond. index score0.30.51.40.8-1.00.40.2-0.1-0.6-0.31.20.2-0.50.21.2-1.0
Pavlov. Cond. latency score0.20.41.60.5-0.60.0-0.10.2-0.8-0.10.90.2-0.30.51.3-1.1
Pavlov. Cond. lever contacts1.92.85.21.6-1.91.81.7-1.6-1.0-2.02.31.6-1.90.41.4-1.6
Pavlov. Cond. magazine entry number0.70.92.20.5-0.41.51.4-1.40.7-1.00.50.6-0.9-0.6-1.00.8
Pavlov. Cond. intertrial magazine entries0.71.63.51.6-1.11.81.9-1.80.6-1.60.70.5-1.3-0.4-1.00.3
Pavlov. Cond. lever-magazine prob. diff.0.20.31.00.7-0.80.20.1-0.0-0.6-0.20.80.1-0.40.31.0-0.9
Pavlov. Cond. response bias0.91.33.31.4-1.81.41.0-0.9-0.3-1.11.80.5-1.1-0.41.0-0.8
Time in closed arm before self-admin0.00.10.20.2-0.1-0.2-0.40.40.30.30.2-0.10.4-0.3-0.30.1
Time in closed arm after self-admin0.20.30.60.3-0.4-0.1-0.30.30.80.7-0.2-0.70.5-0.7-0.50.7
Time in open arm before self-admin1.41.73.7-1.51.4-1.9-1.41.3-1.31.0-1.40.10.91.61.0-0.9
Time in open arm after self-admin0.80.92.7-0.70.20.10.4-0.4-1.3-1.11.01.0-0.91.01.6-1.1
Bone: periosteal estimation1.02.46.82.6-2.11.70.7-0.62.10.11.0-1.4-0.1-2.1-1.51.2
Bone: periosteal perimeter1.42.79.63.1-2.52.21.7-1.61.1-0.81.5-0.5-1.2-1.4-1.00.1
Bone: post-yield work0.40.73.01.7-1.11.00.6-0.50.9-0.00.6-0.9-0.3-1.1-0.70.4
Progressive ratio test 1 active lever presses0.30.62.31.0-1.50.30.3-0.3-0.5-0.50.7-1.0-0.6-0.20.9-1.0
Progressive ratio test 1 breakpoint0.30.62.21.1-1.50.20.3-0.2-0.5-0.40.7-1.0-0.5-0.30.9-0.9
Progressive ratio test 1 inactive lever presses0.30.72.20.6-1.31.00.8-0.8-0.1-0.71.50.0-1.0-0.31.0-0.3
Progressive ratio test 2 active lever presses0.30.41.71.0-0.7-0.4-0.60.70.20.8-0.0-1.30.6-0.7-0.1-0.2
Progressive ratio test 2 breakpoint0.30.41.31.0-0.7-0.4-0.50.60.10.70.1-1.10.5-0.60.0-0.3
Progressive ratio test 2 inactive lever presses0.20.72.11.2-1.2-0.3-0.70.90.40.80.2-1.40.7-1.1-0.3-0.2
Incentive Sensitization - Responses0.10.41.10.7-0.3-0.4-0.80.90.41.00.3-0.60.8-0.7-0.30.0
Incentive Sensitization - Breakpoint0.20.41.00.7-0.3-0.3-0.70.80.51.00.3-0.50.7-0.7-0.30.1
Sum of active levers in priming session hrs 5-61.00.92.2-0.91.1-1.5-0.70.8-1.40.4-1.3-0.20.31.20.6-1.1
Progressive ratio0.10.31.60.1-0.6-0.2-0.30.2-0.30.40.4-1.3-0.1-0.10.9-0.5
Food seeking constrained by brief footshock1.41.73.7-0.41.0-1.6-1.61.60.71.9-1.7-1.31.7-0.4-0.90.9
Seeking ratio, punishment vs. effort0.20.31.3-0.10.7-0.3-0.20.20.50.3-1.10.30.6-0.1-1.10.7
Retroperitoneal fat weight0.62.611.9-3.43.5-0.7-0.4-0.10.51.1-1.30.60.41.0-0.12.0
Reaction time number correct0.41.54.10.7-0.92.01.9-2.00.8-1.50.40.3-1.4-0.7-0.70.8
Reaction time mean minus median0.63.97.2-1.62.1-2.3-2.62.41.32.7-1.5-2.12.5-0.8-1.21.6
Reaction time mean minus median AUC0.64.17.8-2.22.8-2.3-2.52.31.22.5-1.9-1.32.4-0.3-1.21.8
Reaction time num false alarms2.33.910.52.5-2.02.21.1-0.92.9-0.20.8-1.5-0.1-3.2-2.72.2
Reaction time num false alarms AUC1.63.811.02.4-2.12.00.9-0.62.9-0.20.4-1.70.1-3.3-2.72.1
Reaction time trials correct on left0.41.54.10.7-0.92.01.9-2.00.8-1.50.40.3-1.4-0.7-0.70.8
Reaction time trials on left0.41.54.00.7-0.82.01.8-1.90.9-1.50.40.2-1.4-0.8-0.80.9
Reaction time mean3.37.213.2-2.03.2-3.5-3.63.51.03.6-2.6-2.03.5-0.3-1.41.5
Reaction time mean AUC3.07.113.3-2.33.3-3.6-3.63.50.83.6-2.5-1.93.4-0.1-1.11.4
Median of all reaction times4.06.312.3-1.93.1-3.5-3.43.30.53.3-2.7-1.63.30.2-1.11.0
Reaction time omissions1.21.93.6-0.51.4-1.2-1.61.51.41.9-1.0-1.41.8-0.8-1.51.5
Reaction time false alarm rate1.21.75.51.7-1.40.8-0.00.31.90.50.4-1.40.6-2.3-1.71.3
Reaction time premature initiation rate0.20.30.9-0.3-0.3-0.2-0.70.60.60.60.3-0.80.6-1.0-0.10.6
Reaction time premature initiations0.20.72.30.1-0.80.90.3-0.41.3-0.10.5-0.9-0.1-1.5-0.71.3
Std. dev. reaction times1.75.710.6-1.42.3-2.6-3.12.91.73.3-2.1-2.53.1-1.2-1.82.0
Reaction time trials completed0.41.54.00.7-0.82.01.8-1.90.9-1.50.40.2-1.4-0.8-0.80.9
Reaction time trials AUC0.51.84.70.9-1.12.22.0-2.10.9-1.60.40.3-1.5-0.8-0.90.9
Run reversals in cocaine runway, females0.40.41.3-0.1-0.40.80.4-0.61.0-0.30.5-0.1-0.2-0.9-0.61.2
Run reversals in cocaine runway, males0.50.62.0-0.81.2-0.4-0.30.20.60.7-1.40.20.60.4-0.81.0
Latency to leave start box in cocaine runway0.20.20.7-0.60.40.0-0.00.0-0.30.30.50.8-0.00.80.6-0.2
Latency to leave start box in cocaine runway, F0.60.82.20.0-0.10.50.6-0.5-1.0-0.41.21.5-0.71.11.2-1.1
Latency to leave start box in cocaine runway, M0.90.81.8-1.31.3-0.7-0.90.80.71.1-0.8-0.41.00.1-0.41.2
Std. dev. time between licks in bursts0.50.91.91.4-1.11.21.1-1.0-0.3-1.31.00.8-1.1-0.40.4-0.7
Total sessions with >9 infusions0.70.85.10.0-0.4-0.5-1.00.90.71.20.0-2.30.7-0.90.40.6
Short access day 1 total inactive lever presses0.10.10.80.2-0.60.10.0-0.10.40.2-0.4-0.90.1-0.3-0.00.3
Short access day 10 total inactive lever presses0.00.30.5-0.10.3-0.3-0.40.40.60.6-0.4-0.60.5-0.7-0.70.6
Short access day 1 total infusions0.50.94.8-0.50.4-0.9-1.00.90.61.3-0.9-2.20.9-0.60.20.8
Short access day 10 total infusions0.30.51.81.0-1.30.50.2-0.30.2-0.10.8-1.1-0.4-0.70.7-0.2
Short access total infusions0.50.73.4-0.2-0.1-0.9-0.90.90.31.0-0.8-1.80.8-0.40.30.3
Short access day 1 locomotion0.20.42.50.0-0.1-0.1-0.30.20.50.60.3-1.60.2-0.80.50.5
Short access day 10 total locomotion0.20.62.9-0.3-0.3-0.2-0.70.50.91.10.5-1.70.5-1.10.10.8
Short access total locomotion1.01.67.60.1-0.6-0.2-1.00.81.61.40.4-2.80.9-1.9-0.01.4
One hour access (0.3 mA shock)0.70.93.01.7-1.70.90.2-0.00.9-0.00.9-0.7-0.0-1.5-0.50.2
Compulsive drug intake0.91.33.0-1.00.7-1.1-1.21.20.71.5-1.4-1.71.3-0.6-0.80.9
One hour access (shock baseline)0.20.71.61.2-1.21.00.7-0.70.1-0.71.20.7-0.7-0.30.4-0.4
Social response proportion1.62.14.4-1.01.4-2.0-2.02.00.21.7-2.1-0.61.90.2-0.80.4
Social responses0.81.06.32.5-1.70.30.00.20.80.4-0.3-0.90.4-1.1-1.1-0.1
Social time1.42.25.90.4-0.4-0.9-1.51.61.61.6-1.3-2.41.7-1.8-1.61.3
Soleus weight0.51.43.70.9-0.61.10.5-0.61.90.4-0.3-1.40.1-1.8-1.71.8
Bone: stiffness1.93.59.03.0-2.81.50.5-0.42.60.20.1-2.00.4-2.7-2.31.6
Tibialis anterior weight0.10.41.0-1.00.1-0.5-0.40.5-1.0-0.1-0.40.40.00.71.0-0.8
Time to tail flick, vehicle, before self-admin0.70.92.20.4-0.3-0.5-1.01.11.11.2-0.2-1.21.1-1.5-0.70.9
Time to tail flick, vehicle, after self-admin0.91.85.2-2.32.3-1.8-1.31.3-0.60.5-1.90.71.10.80.20.2
Time to tail flick, test, before self-admin0.40.41.3-0.71.10.10.1-0.10.70.1-0.91.10.3-0.1-0.61.0
Time to tail flick, test, after self-admin0.10.10.20.10.10.30.4-0.50.1-0.0-0.4-0.2-0.30.1-0.30.2
Delta time to tail flick, vehicle, before/after SA2.22.46.4-1.21.4-0.40.7-0.6-2.3-1.5-0.42.5-1.02.51.2-1.8
Delta time to tail flick, test, before/after SA0.10.20.3-0.2-0.0-0.5-0.40.4-0.50.40.0-0.50.20.60.3-0.5
Tibia length2.46.717.94.0-3.63.22.7-2.6-0.6-1.64.20.9-2.60.11.3-1.9
Ambulatory time before self-admin0.41.23.11.7-1.61.41.0-1.00.4-0.51.8-0.8-1.0-0.80.5-0.1
Ambulatory time after self-admin0.81.35.52.4-1.71.31.0-0.80.9-0.60.6-1.2-0.5-1.3-1.00.3
Bone: tissue strength0.70.71.30.9-0.91.10.8-0.81.2-0.10.1-0.5-0.4-1.1-1.11.0
Total heroin consumption0.50.61.7-1.00.4-1.3-0.70.6-1.10.2-1.0-0.70.30.80.7-0.8
Bone: trabecular number1.42.77.4-1.31.0-0.50.2-0.2-2.4-1.00.72.6-0.82.72.3-2.1
Bone: trabecular spacing1.11.64.50.9-1.41.00.2-0.22.00.30.1-1.70.3-2.1-1.11.8
Bone: trabecular thickness0.10.20.9-0.10.9-0.20.1-0.1-0.5-0.20.10.8-0.10.70.1-0.4
Bone: trabecular tissue density0.20.31.41.2-1.00.60.6-0.60.3-0.1-0.3-0.5-0.4-0.4-0.50.0
Water consumed over 24 hours1.01.93.81.5-2.01.51.4-1.3-0.8-1.51.90.7-1.60.41.2-1.4
Number of responses in last shaping day0.50.71.4-0.90.9-1.1-0.70.6-1.10.4-0.10.10.21.11.2-1.0