Hub : Genes

Slc35g1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Slc35g1 0.34 0.18 1.5e-04 0.15 0.1 0.08 0.17 2.3e-04 1.9e-03 6.8e-03 9.0e-05
2 Eye mRNA stability Slc35g1 0.49 0.16 1.9e-04 0.08 0.09 0.06 0.13 2.2e-02 2.0e-02 4.0e-02 5.1e-03
3 LHb mRNA stability Slc35g1 0.19 0.11 4.6e-04 0.09 0.12 0.09 0.12 3.4e-03 8.7e-04 3.4e-03 9.9e-04
4 Brain gene expression Slc35g1 0.1 0.06 5.1e-08 0.09 0.09 0.08 0.08 7.6e-09 2.2e-08 4.0e-08 3.5e-08
5 Eye gene expression Slc35g1 0.39 0.2 5.5e-03 0.08 0.11 0.07 0.12 2.7e-02 9.5e-03 2.9e-02 7.0e-03
6 Liver gene expression Slc35g1 0.06 0.04 7.0e-05 0.02 0.03 0.03 0.02 2.6e-03 5.2e-04 4.2e-04 1.7e-03
7 BLA gene expression Slc35g1 0.52 0.15 1.7e-03 0 0.03 0.03 0.04 3.2e-01 7.7e-03 9.2e-03 2.8e-03
8 IC gene expression Slc35g1 0.75 0 5.2e-09 0.21 0.23 0.3 0.29 4.2e-09 4.1e-10 6.8e-13 9.8e-13
9 NAcc gene expression Slc35g1 0.56 0.04 0.0e+00 0.16 0.2 0.22 0.21 2.3e-23 3.9e-30 2.6e-32 5.8e-31
10 pVTA gene expression Slc35g1 0.63 0.04 4.4e-14 0.13 0.18 0.2 0.2 1.6e-10 8.4e-15 3.1e-16 3.7e-16
11 PL gene expression Slc35g1 0.45 0.11 3.6e-07 0.02 0.08 0.08 0.08 1.0e-03 9.6e-09 1.8e-09 7.2e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density2.13.87.62.72.72.72.8-2.22.0-1.60.1-0.10.70.7
Area under the delay curve0.20.21.0-1.0-0.4-0.4-0.30.90.5-0.2-0.30.20.20.1
BMI with tail0.20.51.41.00.71.20.8-1.10.90.10.1-0.4-0.0-0.1
BMI without tail0.10.51.9-0.5-0.4-0.2-0.40.1-0.3-0.70.71.41.01.1
Body weight0.10.62.11.50.30.40.3-0.7-0.4-0.2-1.3-0.5-0.9-0.6
Weight adjusted by age0.10.31.10.30.40.40.3-0.20.10.4-1.0-0.9-0.6-1.0
Bone surface1.93.86.32.52.42.52.4-2.51.9-1.90.50.71.21.2
Bone volume1.73.47.82.82.52.52.6-2.41.4-1.5-0.3-0.00.50.5
Breakpoint value in progressive ratio session0.20.41.70.1-0.3-0.3-0.20.60.50.2-1.3-0.6-0.9-0.7
Number of licking bursts0.30.83.2-1.8-1.1-1.0-1.11.40.10.1-0.10.50.50.3
Context. condit. distance diff. score1.61.96.32.51.31.51.4-1.41.20.1-0.7-1.6-1.1-0.8
Locomotion velocity, session 10.80.93.4-1.6-1.1-1.2-1.21.80.10.40.10.10.10.2
Locomotion distance, session 11.72.24.50.2-1.0-0.8-0.91.40.11.8-2.0-2.1-1.9-2.0
Locomotion velocity, session 24.25.010.7-1.00.70.80.8-0.42.5-3.12.73.03.13.3
Locomotion distance, session 20.20.21.40.1-0.30.1-0.20.21.2-0.2-0.8-0.2-0.4-0.2
Locomotion velocity, session 30.20.20.40.70.60.60.7-0.30.4-0.5-0.0-0.1-0.00.1
Locomotion distance, session 30.40.52.21.50.50.40.6-0.5-0.50.3-0.4-0.9-0.8-0.6
Stereotopy head waving bouts, day 31.01.23.1-0.50.50.40.60.00.6-1.31.51.31.71.5
Stereotopy head waving duration, day 30.80.92.1-0.50.50.50.5-0.31.2-1.11.21.01.41.3
Locomotion velocity, session 72.02.26.12.51.81.81.9-2.20.9-0.3-0.7-1.1-0.6-0.5
Locomotion distance, session 71.21.54.72.21.31.51.5-2.10.7-0.4-0.5-0.5-0.3-0.2
Stereotopy head waving bouts, day 70.50.61.8-0.40.4-0.00.40.80.8-0.71.30.31.01.0
Stereotopy head waving duration, day 70.40.51.9-0.20.60.10.50.50.2-0.71.40.30.91.0
Locomotion velocity, session 80.40.51.31.10.50.70.5-0.31.10.10.0-1.0-0.6-0.4
Locomotion distance, session 81.21.84.91.91.01.41.0-1.12.20.1-1.0-1.6-1.1-0.9
Degree of sensitization distance0.30.31.80.20.30.60.4-0.71.3-0.5-0.40.20.20.2
Degree of sensitization stereotypy0.30.31.4-0.4-0.1-0.5-0.11.20.4-0.00.9-0.20.30.4
Conditioned locomotion0.20.31.3-0.20.10.00.1-0.7-1.20.5-0.5-0.2-0.4-0.6
Cocaine response after cond. corrected0.91.33.4-1.4-0.5-0.4-0.5-0.00.4-1.01.61.81.61.5
Cocaine response after cond. not corrected0.81.22.8-1.1-0.3-0.3-0.20.10.8-1.21.61.71.51.5
Cocaine response before conditioning0.20.20.60.60.20.10.20.70.70.1-0.4-0.8-0.5-0.3
Saline control response2.02.86.3-1.1-1.6-1.6-1.62.5-0.51.6-2.1-1.5-1.8-1.8
Bone: connectivity density3.35.39.32.63.03.03.0-2.61.9-2.31.21.01.71.7
Bone: cortical apparent density0.20.41.2-0.6-0.7-0.5-0.71.10.20.80.5-0.7-0.1-0.2
Bone: cortical area1.42.27.42.70.90.80.9-1.0-0.50.5-2.1-1.7-1.9-1.5
Bone: cortical porosity1.51.64.40.81.21.51.1-1.22.1-1.40.90.71.21.2
Bone: cortical porosity1.81.93.20.91.31.41.2-1.31.8-1.81.31.11.51.5
Bone: cortical thickness2.64.38.60.5-1.4-1.4-1.41.4-1.62.4-2.9-2.5-2.9-2.8
Bone: cortical thickness3.54.38.10.4-1.4-1.4-1.41.9-0.72.4-2.8-2.8-2.8-2.7
Bone: cortical tissue density0.20.41.1-0.7-0.6-0.5-0.61.10.30.80.7-0.60.0-0.1
Condit. Reinf. active minus inactive responses0.00.00.1-0.1-0.2-0.3-0.00.3-0.2-0.1-0.00.2-0.00.1
Condit. Reinf. active-inactive response ratio0.30.41.0-0.7-0.3-0.4-0.00.4-0.6-0.41.00.90.60.8
Condit. Reinf. active responses0.30.41.20.4-0.3-0.3-0.20.3-0.50.6-1.1-0.6-0.9-0.8
Condit. Reinf. inactive responses0.81.03.20.7-0.3-0.1-0.30.10.11.1-1.8-1.4-1.5-1.4
Incentive salience index mean0.50.61.0-0.5-1.0-1.0-0.80.9-0.90.7-0.9-0.3-0.8-0.7
Condit. Reinf. lever presses1.82.64.0-1.3-2.0-1.8-1.81.5-1.61.9-1.7-0.9-1.6-1.6
Condit. Reinf. active minus inactive responses1.11.73.51.91.81.91.9-1.70.9-0.90.3-0.10.50.4
Condit. Reinf. active-inactive response ratio0.71.12.10.91.31.51.4-1.30.9-0.70.90.30.80.7
Condit. Reinf. active responses0.71.12.81.70.70.60.7-0.5-0.50.6-1.3-1.3-1.2-1.2
Condit. Reinf. inactive responses1.82.64.70.3-1.2-1.3-1.21.3-1.91.7-2.1-1.6-2.2-2.0
Condit. Reinf. lever presses0.20.31.2-0.9-0.6-0.7-0.61.1-0.3-0.00.20.40.20.3
Condit. Reinf. lever reinforcers received0.60.91.81.30.40.40.4-0.2-0.50.8-1.3-1.3-1.2-1.2
Conditioned reinforcement - actives0.20.72.00.60.60.50.80.31.1-1.41.00.40.90.9
Conditioned reinforcement - inactives0.92.54.61.31.51.31.6-0.71.9-2.22.00.71.71.7
Conditioned locomotion0.10.20.50.50.1-0.10.10.4-0.2-0.60.60.30.70.7
Patch foraging indifference point 0 sec0.41.12.1-1.5-1.2-1.4-1.01.4-1.5-0.0-0.11.00.30.3
Patch foraging indifference point AUC1.22.86.7-1.5-2.2-2.3-2.22.6-1.01.1-1.5-0.6-1.1-0.9
Delay disc. indifference point, 0s delay1.01.13.30.61.81.51.7-0.61.5-0.90.10.10.60.3
Delay disc. indifference point, 16s delay0.20.21.1-0.2-0.7-0.6-0.41.10.40.3-0.50.0-0.2-0.3
Delay disc. indifference point, 2s delay0.20.20.5-0.60.20.20.10.00.4-0.50.20.50.70.7
Delay disc. indifference point, 24s delay0.40.71.8-0.9-1.3-1.2-1.21.30.10.2-0.40.1-0.2-0.0
Delay disc. indifference point, 4s delay0.20.20.9-0.7-0.3-0.2-0.21.00.80.0-0.4-0.1-0.0-0.2
Delay disc. indifference point, 8s delay0.81.35.0-2.2-1.4-1.5-1.31.6-0.50.3-0.50.30.1-0.1
Indifference point function ln k1.03.16.62.12.42.42.5-2.60.9-1.31.10.30.70.9
Indifference point function log k1.03.16.62.12.42.42.5-2.60.9-1.31.10.30.70.9
Patch foraging total patch changes 0 sec0.41.12.5-1.5-1.1-1.4-0.91.5-1.6-0.10.01.10.30.4
Patch foraging total patch changes 12 sec2.73.69.0-2.6-2.5-2.7-2.43.0-1.51.3-0.40.2-0.3-0.5
Patch foraging total patch changes 18 sec0.40.92.7-1.6-1.1-1.3-1.11.6-0.50.1-0.20.60.20.3
Patch foraging total patch changes 24 sec0.20.81.9-1.4-0.9-1.4-0.91.2-1.2-0.3-0.60.6-0.00.1
Patch foraging total patch changes 6 sec2.34.010.3-2.7-2.6-2.9-2.63.2-1.60.5-0.10.90.10.2
Patch foraging time to switch 0 sec0.20.72.4-1.6-1.1-0.9-1.20.80.20.40.50.40.40.2
Patch foraging water rate 0 sec0.31.12.61.21.51.21.6-1.20.3-1.20.50.40.60.6
Patch foraging water rate 12 sec0.10.41.11.10.90.70.8-0.70.3-0.80.0-0.0-0.10.2
Patch foraging water rate 18 sec0.51.22.61.61.31.31.5-1.31.1-1.20.10.10.30.3
Patch foraging water rate 24 sec0.40.51.30.90.80.90.9-1.20.5-1.0-0.2-0.0-0.10.3
Patch foraging water rate 6 sec0.10.10.40.60.30.40.4-0.40.2-0.0-0.2-0.5-0.4-0.2
Seeking ratio, delayed vs. immediate footshock0.10.20.60.1-0.1-0.5-0.30.2-0.80.3-0.6-0.3-0.7-0.5
Distance traveled before self-admin0.71.42.50.11.21.01.2-0.71.2-1.61.21.41.31.5
Distance traveled after self-admin1.62.84.70.81.91.81.8-1.42.2-1.81.41.32.01.7
Extensor digitorum longus weight0.51.95.62.40.91.00.7-1.20.30.6-1.9-1.7-1.7-1.4
Bone: elastic displacement0.30.41.2-0.80.40.20.4-0.2-0.20.01.00.71.10.7
Bone: elastic work0.40.51.40.61.21.01.2-0.70.8-0.20.3-0.10.60.3
Bone: endosteal estimation3.07.413.63.53.43.43.4-3.72.3-3.00.61.01.41.7
Bone: endosteal perimeter2.66.315.23.93.43.43.3-3.32.2-1.9-0.5-0.20.10.5
Epididymis fat weight0.52.35.02.21.61.61.6-1.9-0.50.6-1.5-1.7-1.2-1.3
Delta time in closed arm before/after self-admin0.60.61.5-0.8-0.9-0.9-0.90.5-1.2-0.30.20.90.30.6
Delta time in open arm before/after self-admin1.41.65.40.51.41.51.4-0.82.3-1.11.20.81.21.1
Diff in mean of infusions in LGA sessions0.71.22.00.91.41.41.4-1.21.0-1.30.80.80.80.9
Delay discount exponential model param0.20.31.31.10.50.50.4-0.9-0.50.30.2-0.3-0.3-0.2
Extinction: sum of active levers before priming0.10.20.40.6-0.4-0.3-0.40.0-0.4-0.5-0.50.4-0.10.2
Active lever presses in extinction session 63.33.310.02.32.12.52.1-2.03.2-1.3-0.3-0.30.30.4
Bone: final force0.20.31.51.20.10.20.1-0.30.1-0.2-1.1-0.3-0.7-0.4
Bone: final moment0.10.21.01.00.10.20.1-0.5-0.1-0.3-0.80.1-0.3-0.2
Food consumed during 24 hour testing period0.20.40.9-0.4-0.6-0.6-0.50.5-0.3-0.60.91.00.80.9
Glucose0.00.10.40.60.20.10.2-0.0-0.3-0.10.1-0.0-0.20.0
Heart weight0.61.05.0-0.7-1.0-1.1-0.90.0-2.2-0.00.51.20.60.6
Delay discount hyperbolic model param0.20.31.41.20.40.40.3-0.8-0.40.40.0-0.5-0.5-0.4
Intermittent access intake day 1-15 change0.42.33.21.11.81.61.7-1.71.0-1.71.51.41.31.7
Intermittent access intake escalation0.52.74.91.62.22.02.1-1.91.1-1.61.41.11.11.5
Intermittent access intake escalation 22.74.66.71.22.62.42.4-2.01.9-2.42.31.82.02.3
Intermitt. access day 1 inactive lever presses0.10.81.9-0.50.60.50.6-0.30.7-0.91.21.21.41.1
Intermitt. access day 15 inactive lever presses0.10.71.91.41.10.91.3-0.60.1-0.70.7-0.00.70.5
Intermitt. access escalation Index0.10.30.6-0.30.70.30.7-0.8-0.40.40.4-0.8-0.3-0.2
Intermittent access day 1 total infusions0.20.72.81.71.01.01.0-0.50.8-0.30.2-0.90.0-0.0
Intermittent access day 15 total infusions0.82.06.32.51.91.82.0-1.70.6-0.80.9-0.50.20.5
Intermittent access terminal intake (last 3 days)1.22.25.42.32.01.82.0-1.51.1-0.91.3-0.40.40.7
Intermittent access total infusions1.01.25.32.31.31.31.4-0.90.5-0.10.4-1.3-0.3-0.2
Intermittent access day 1 locomotion0.20.41.71.30.50.80.5-0.70.4-0.00.4-0.50.20.1
Intermittent access day 15 total locomotion0.10.21.01.00.10.20.00.10.60.5-0.1-0.8-0.3-0.4
Intermittent access total locomotion0.70.93.41.90.71.00.7-0.61.30.1-0.1-1.2-0.3-0.3
Intermittent access standard deviation0.83.96.71.61.91.71.8-1.51.5-2.52.31.92.12.6
Left kidney weight0.00.40.80.3-0.9-0.8-0.80.4-0.80.0-0.6-0.4-0.7-0.3
Right kidney weight0.31.93.7-0.4-1.8-1.9-1.81.5-1.80.8-1.3-0.7-1.3-1.0
Cocaine induced anxiety0.41.02.60.31.61.51.6-1.40.9-0.60.50.00.50.3
Post-drug Anxiety0.40.51.5-0.60.1-0.00.1-0.4-1.21.1-0.6-0.4-0.7-0.9
Baseline Anxiety1.01.74.3-0.9-1.7-1.6-1.60.8-2.11.4-1.1-0.2-1.0-1.0
Tail length0.10.41.50.1-0.0-0.5-0.10.3-1.0-1.2-0.60.90.20.5
Length with tail0.10.62.61.0-0.2-0.6-0.30.3-0.8-0.4-1.6-0.6-1.1-0.6
Length without tail0.52.66.72.60.70.80.7-1.11.00.4-2.2-2.3-2.1-1.8
Times rat made contact with spout1.21.42.9-0.60.70.60.6-0.21.0-1.71.11.61.71.6
Lifetime Intake0.81.04.82.21.11.11.2-0.60.40.00.1-1.3-0.3-0.3
Liver weight, left0.61.02.50.6-0.8-0.6-0.70.1-0.90.8-1.5-1.2-1.6-1.2
Liver weight, right0.30.41.00.90.70.70.8-0.90.4-1.0-0.30.30.40.3
Locomotor activity0.60.92.0-0.30.80.30.90.00.3-1.40.91.21.41.2
Locomotor testing distance0.51.22.9-0.60.70.20.80.40.5-1.61.21.41.71.4
Locomotor testing rearing0.31.12.61.21.61.21.6-0.61.2-1.20.30.30.80.5
Locomotion in novel chamber2.43.26.82.42.22.62.2-2.42.5-0.90.3-0.60.4-0.1
Locomotion in novel chamber post-restriction0.61.73.41.5-0.6-0.1-0.70.60.91.3-1.7-1.8-1.6-1.9
Fecal boli incidents, locomotor time 10.41.12.51.41.21.31.4-1.11.6-0.90.1-0.50.20.4
Change in fecal boli incidents, locomotor task1.01.11.7-0.8-1.0-1.2-1.21.3-1.31.0-1.0-0.5-1.0-0.8
Time >=10cm from walls, locomotor time 10.20.20.80.9-0.1-0.2-0.3-0.10.1-0.1-0.3-0.6-0.9-0.4
Bouts of movement, locomotor time 10.70.92.90.70.1-0.10.30.40.10.8-1.3-1.7-1.4-1.5
Total resting periods, locomotor time 10.80.93.00.60.0-0.20.30.70.50.8-1.2-1.7-1.3-1.4
Rest time, locomotor task time 10.20.41.50.30.80.41.20.11.2-0.0-0.5-0.7-0.0-0.3
Distance moved, locomotor task time 10.20.72.4-0.6-1.1-0.9-1.40.5-1.60.10.00.8-0.0-0.0
Vertical activity count, locomotor time 10.10.81.7-1.1-1.0-0.9-1.30.3-1.3-0.10.81.10.30.4
Time >=10cm from walls, locomotor time 20.00.10.40.00.60.10.5-0.20.3-0.60.40.20.10.3
Bouts of movement, locomotor time 20.20.83.4-1.6-0.9-1.1-0.91.80.4-0.20.10.10.20.2
Total resting periods, locomotor time 20.20.83.7-1.5-0.8-1.0-0.91.90.6-0.3-0.10.00.10.1
Rest time, locomotor task time 20.61.02.60.0-0.3-0.3-0.21.01.10.7-1.6-1.6-1.4-1.3
Distance moved, locomotor task time 20.30.41.40.40.50.30.2-1.0-1.2-0.50.60.90.60.3
Vertical activity count, locomotor time 21.12.67.6-1.20.30.10.3-0.8-0.4-1.52.52.82.42.2
Light reinforcement 10.10.51.1-0.1-0.7-0.5-0.60.80.11.0-0.7-1.0-0.5-0.9
Light reinforcement 20.40.91.7-1.2-1.0-0.9-1.11.20.61.3-0.1-1.1-0.3-0.7
Bone: marrow area3.17.714.03.53.53.53.5-3.72.3-3.00.71.01.51.7
Bone: maximum diameter3.57.121.64.63.63.53.5-3.41.8-1.3-0.8-1.2-0.6-0.2
Bone: maximum force0.71.46.52.51.11.41.1-1.11.0-0.5-1.0-0.9-0.7-0.4
Bone: maximum moment0.61.25.22.31.11.31.1-1.20.8-0.7-0.8-0.4-0.3-0.1
Mean time between licks in bursts0.10.73.6-1.0-0.7-1.0-0.60.8-1.90.30.30.60.00.1
Mean num. licks in bursts0.61.63.11.71.71.61.7-1.70.7-1.10.70.30.40.6
Cd content in liver0.80.91.9-1.4-1.1-1.3-1.11.1-1.10.30.90.50.30.4
Co content in liver2.12.58.1-2.2-1.5-1.9-1.61.3-2.80.51.11.20.70.5
Cu content in liver2.53.010.1-3.2-2.2-2.2-2.12.6-0.30.70.40.70.40.2
Fe content in liver1.31.64.2-2.0-1.7-1.7-1.61.7-0.81.0-0.00.1-0.2-0.3
K content in liver0.20.21.9-0.3-0.20.0-0.00.21.4-0.0-0.3-0.3-0.1-0.2
Mg content in liver0.20.21.2-0.6-0.6-0.3-0.30.21.10.2-0.2-0.2-0.2-0.3
Mn content in liver1.51.72.9-0.7-1.3-0.7-1.41.31.71.4-0.9-1.7-1.2-1.3
Na content in liver0.50.61.2-0.7-1.1-0.8-0.91.00.71.00.0-0.6-0.6-0.6
Rb content in liver0.10.10.20.10.30.20.5-0.50.1-0.50.20.20.40.2
Se content in liver11.113.143.0-6.6-4.9-4.8-4.94.8-0.91.41.11.80.90.7
Sr content in liver0.20.20.6-0.4-0.4-0.4-0.40.50.4-0.10.70.20.30.4
Zn content in liver2.02.48.4-2.9-1.6-1.6-1.31.3-0.0-0.41.41.81.51.2
Bone: minimum diameter3.77.117.24.13.53.33.5-3.81.1-2.50.70.60.81.3
Time in familiar zone, hab. session 10.20.30.70.10.60.60.4-0.50.2-0.30.60.40.80.6
Time in novel zone, hab. session 10.20.20.5-0.6-0.6-0.6-0.50.70.1-0.20.00.40.10.2
Total zone transitions, hab. session 10.40.61.40.6-0.00.20.10.40.90.6-1.1-1.2-0.9-1.0
Total locomotion distance, hab. session 10.81.12.6-1.0-1.2-1.1-1.01.60.11.1-1.1-0.7-0.8-1.0
Locomotion velocity, hab. session 11.72.44.7-1.3-1.8-1.6-1.62.2-0.31.7-1.5-1.2-1.4-1.6
Time in familiar zone, hab. session 20.30.42.8-0.4-0.3-0.6-0.40.5-1.70.4-0.3-0.3-0.3-0.4
Time in novel zone, hab. session 20.10.10.8-0.1-0.00.10.0-0.00.9-0.20.50.40.40.4
Total zone transitions, hab. session 21.72.14.60.2-1.1-0.9-1.11.1-0.61.6-2.1-1.8-2.0-2.0
Total locomotion distance, hab. session 21.72.24.1-0.3-1.4-1.3-1.41.4-1.21.7-2.0-1.4-1.7-1.8
Locomotion velocity, hab. session 21.72.34.4-0.4-1.5-1.3-1.51.4-0.91.7-2.1-1.5-1.8-2.0
Novel to familiar place preference ratio5.16.711.60.62.42.32.4-1.83.4-3.42.62.33.03.0
Novelty place preference5.36.711.70.62.42.42.4-1.83.4-3.42.62.23.03.0
Time in novel zone, NPP test5.66.811.90.72.52.42.5-1.83.3-3.52.62.33.03.1
Total zone transitions, NPP test1.82.65.4-0.0-1.4-1.1-1.31.2-0.71.8-2.3-1.8-2.2-2.2
Total locomotion distance, NPP test2.23.04.6-1.0-1.9-1.7-1.92.1-0.91.8-2.0-1.5-1.9-1.9
Locomotion velocity, NPP test2.02.94.1-0.9-1.9-1.7-1.92.0-0.81.7-2.0-1.5-1.9-1.9
Intraocular pressure0.20.30.8-0.3-0.7-0.5-0.70.9-0.60.5-0.4-0.4-0.2-0.2
Delta distance traveled before/after self-admin0.70.81.81.11.21.41.0-1.21.1-0.40.2-0.00.60.2
Delta ambulatory time before/after self-admin0.71.32.81.71.51.71.3-1.61.1-0.40.1-0.40.40.1
Parametrial fat weight0.51.22.5-0.6-1.3-1.4-1.21.1-1.60.8-1.1-0.7-1.3-0.9
Pavlov. Cond. lever latency0.30.31.1-0.30.2-0.0-0.10.1-0.3-0.61.10.70.80.9
Pavlov. Cond. magazine entry latency0.50.61.5-1.0-1.1-1.2-1.00.8-0.9-0.00.40.70.20.3
Pavlov. Cond. change in total contacts0.20.30.8-0.4-0.5-0.4-0.10.1-0.3-0.30.90.80.60.7
Pavlov. Cond. index score0.20.30.7-0.5-0.9-0.8-0.60.6-0.30.4-0.3-0.1-0.4-0.4
Pavlov. Cond. latency score0.20.30.6-0.2-0.7-0.6-0.50.6-0.30.5-0.7-0.3-0.5-0.6
Pavlov. Cond. lever contacts0.50.51.2-0.3-0.9-0.6-0.60.4-0.20.9-1.1-0.6-0.9-0.9
Pavlov. Cond. magazine entry number0.30.40.80.60.50.60.5-0.00.60.2-0.9-0.9-0.7-0.6
Pavlov. Cond. intertrial magazine entries0.70.82.30.5-0.2-0.1-0.00.2-0.21.0-1.5-1.3-1.5-1.2
Pavlov. Cond. lever-magazine prob. diff.0.20.20.6-0.6-0.8-0.8-0.60.6-0.30.4-0.2-0.0-0.3-0.3
Pavlov. Cond. response bias0.30.40.9-0.8-0.7-0.7-0.50.2-0.4-0.20.60.90.50.5
Pavlov. Cond. lever latency1.21.74.52.11.61.61.6-1.50.90.1-0.5-1.4-0.7-0.8
Pavlov. Cond. magazine entry latency1.31.95.4-1.7-0.7-0.8-0.70.3-0.5-1.11.72.31.71.8
Pavlov. Cond. change in total contacts0.30.71.6-1.3-1.0-1.1-1.00.9-0.80.00.00.90.20.3
Pavlov. Cond. index score1.01.53.7-1.9-1.2-1.3-1.31.1-0.7-0.50.91.70.91.1
Pavlov. Cond. latency score0.81.32.9-1.7-1.0-1.1-1.10.9-0.5-0.71.01.71.01.2
Pavlov. Cond. lever contacts1.21.84.4-2.1-1.7-1.8-1.71.7-1.20.20.11.10.30.4
Pavlov. Cond. magazine entry number1.51.95.22.31.71.81.6-1.31.3-0.0-0.7-1.5-0.6-0.7
Pavlov. Cond. intertrial magazine entries0.71.54.72.21.51.61.5-1.30.60.1-0.7-1.2-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.1.01.53.4-1.9-1.1-1.2-1.11.0-0.6-0.71.01.81.11.3
Pavlov. Cond. response bias1.42.05.1-2.3-1.6-1.7-1.61.5-1.3-0.20.61.70.80.9
Time in closed arm before self-admin0.50.81.60.91.31.11.2-0.71.2-0.90.50.30.90.5
Time in closed arm after self-admin0.30.31.70.1-0.3-0.4-0.40.4-0.70.3-1.3-0.2-0.5-0.7
Time in open arm before self-admin0.30.41.4-0.4-0.5-0.4-0.4-0.1-1.20.9-0.6-0.4-0.6-0.5
Time in open arm after self-admin0.30.31.2-0.30.30.50.40.11.1-0.50.70.50.50.6
Bone: periosteal estimation1.94.514.13.72.72.72.7-2.91.4-1.6-0.8-0.4-0.20.2
Bone: periosteal perimeter2.03.913.13.62.52.52.5-2.51.0-0.7-1.2-1.0-0.8-0.4
Bone: post-yield work0.81.35.82.41.11.51.2-1.20.9-1.1-0.4-0.2-0.10.4
Progressive ratio test 1 active lever presses0.51.03.41.80.50.70.60.00.80.6-0.6-1.7-1.0-0.9
Progressive ratio test 1 breakpoint0.50.92.81.70.30.50.40.30.60.7-0.7-1.7-1.1-1.0
Progressive ratio test 1 inactive lever presses0.41.02.51.61.31.31.4-0.61.2-1.00.5-0.20.70.3
Progressive ratio test 2 active lever presses1.42.05.32.32.01.82.0-0.91.8-1.00.2-0.90.20.1
Progressive ratio test 2 breakpoint1.62.15.62.42.11.82.1-0.91.7-1.00.2-0.90.10.0
Progressive ratio test 2 inactive lever presses0.41.33.01.71.61.51.7-0.51.6-0.50.6-0.70.40.1
Incentive Sensitization - Responses1.13.05.51.52.42.02.3-1.42.1-2.21.10.41.21.2
Incentive Sensitization - Breakpoint1.22.65.11.52.31.92.2-1.42.0-2.11.00.21.01.1
Sum of active levers in priming session hrs 5-61.11.13.1-1.5-0.4-0.6-0.40.3-0.5-0.61.01.81.41.3
Progressive ratio0.30.92.7-0.4-0.6-0.7-0.70.1-1.61.1-1.3-0.7-1.1-1.2
Food seeking constrained by brief footshock0.10.20.40.4-0.2-0.4-0.30.7-0.3-0.7-0.5-0.1-0.4-0.1
Seeking ratio, punishment vs. effort0.40.92.7-0.4-0.1-0.2-0.10.80.9-1.70.91.31.21.4
Retroperitoneal fat weight0.21.02.30.3-0.5-0.5-0.50.1-1.51.0-1.5-1.3-1.4-1.2
Reaction time number correct0.72.55.41.82.12.22.1-2.31.8-0.9-0.6-0.7-0.3-0.2
Reaction time mean minus median0.21.44.1-0.30.3-0.00.3-0.7-1.0-1.22.01.71.51.7
Reaction time mean minus median AUC0.21.64.1-1.00.3-0.10.2-0.7-1.2-1.12.01.91.61.7
Reaction time num false alarms0.30.51.90.4-0.6-0.5-0.40.5-0.60.1-1.4-0.5-1.0-0.7
Reaction time num false alarms AUC0.10.30.7-0.0-0.6-0.6-0.40.6-0.8-0.4-0.90.2-0.4-0.1
Reaction time trials correct on left0.72.55.41.82.12.22.1-2.31.8-0.9-0.6-0.7-0.3-0.2
Reaction time trials on left0.72.45.41.82.12.12.1-2.31.7-0.9-0.6-0.7-0.3-0.2
Reaction time mean1.02.24.2-1.7-1.3-1.5-1.10.8-2.0-0.71.62.11.51.5
Reaction time mean AUC0.92.24.1-1.9-1.6-1.6-1.51.0-2.0-0.41.51.81.21.3
Median of all reaction times1.21.93.2-1.7-1.4-1.6-1.31.0-1.8-0.51.11.71.21.2
Reaction time omissions1.01.64.2-0.30.50.10.5-1.3-1.1-1.12.01.71.61.6
Reaction time false alarm rate0.91.22.6-0.8-1.5-1.5-1.41.6-1.50.2-0.70.3-0.3-0.2
Reaction time premature initiation rate0.40.71.5-0.7-1.1-1.2-1.11.2-1.1-0.1-0.20.1-0.3-0.2
Reaction time premature initiations0.10.20.50.40.0-0.10.1-0.1-0.3-0.3-0.6-0.6-0.7-0.5
Std. dev. reaction times0.72.55.7-1.3-0.5-0.9-0.5-0.1-2.3-1.22.22.41.81.9
Reaction time trials completed0.72.45.41.82.12.12.1-2.31.7-0.9-0.6-0.7-0.3-0.2
Reaction time trials AUC0.62.25.01.62.02.02.0-2.21.7-0.9-0.6-0.7-0.3-0.3
Run reversals in cocaine runway, females0.50.51.2-1.0-0.5-0.4-0.60.60.3-0.90.31.00.81.1
Run reversals in cocaine runway, males2.72.94.8-1.0-2.1-1.9-2.12.2-1.11.9-1.2-1.5-1.7-1.6
Latency to leave start box in cocaine runway0.81.13.01.51.51.41.4-1.7-0.50.0-0.4-0.5-0.2-0.5
Latency to leave start box in cocaine runway, F1.41.83.92.02.01.91.9-2.00.2-0.3-0.3-0.4-0.0-0.3
Latency to leave start box in cocaine runway, M0.10.10.7-0.10.20.10.2-0.5-0.8-0.0-0.00.20.10.1
Std. dev. time between licks in bursts1.32.44.3-2.1-2.1-1.9-2.01.6-2.01.7-0.3-0.0-0.6-0.7
Total sessions with >9 infusions0.20.21.00.1-0.4-0.3-0.41.0-0.20.5-0.4-0.6-0.2-0.6
Short access day 1 total inactive lever presses1.02.04.42.11.72.11.8-1.61.80.10.3-1.00.3-0.0
Short access day 10 total inactive lever presses0.00.10.4-0.60.50.00.4-0.00.0-0.50.20.40.3-0.0
Short access day 1 total infusions0.20.41.30.3-0.5-0.3-0.31.00.10.9-0.5-1.2-0.5-0.8
Short access day 10 total infusions0.40.71.90.1-0.8-0.9-0.71.4-1.01.0-0.3-0.9-0.5-0.6
Short access total infusions0.30.41.61.30.40.50.50.30.50.2-0.1-1.1-0.2-0.3
Short access day 1 locomotion0.10.10.80.30.20.60.30.10.90.2-0.1-0.30.3-0.0
Short access day 10 total locomotion0.00.20.4-0.3-0.5-0.1-0.5-0.00.7-0.10.50.10.40.4
Short access total locomotion0.10.20.7-0.2-0.20.0-0.20.40.6-0.10.60.30.90.5
One hour access (0.3 mA shock)3.13.67.32.72.62.42.6-1.82.1-1.81.1-0.30.70.9
Compulsive drug intake0.60.82.00.51.41.11.4-1.30.1-0.90.80.20.50.6
One hour access (shock baseline)0.10.41.81.40.60.60.6-0.30.7-0.4-0.1-0.5-0.2-0.1
Social response proportion1.82.34.92.11.92.22.0-2.21.7-0.00.2-0.8-0.0-0.2
Social responses0.50.62.21.50.61.10.9-0.90.60.5-0.0-0.7-0.3-0.4
Social time0.30.41.1-0.4-1.1-0.6-0.90.6-0.21.0-0.4-0.1-0.6-0.6
Soleus weight0.72.26.12.01.82.01.8-2.51.0-1.3-0.20.30.70.5
Bone: stiffness1.22.29.53.11.21.41.2-1.10.9-0.3-1.5-1.6-1.4-1.0
Tibialis anterior weight0.51.95.12.21.71.71.6-1.61.3-0.5-1.1-0.9-0.5-0.5
Time to tail flick, vehicle, before self-admin0.20.20.9-0.9-0.3-0.1-0.30.71.00.3-0.0-0.40.1-0.3
Time to tail flick, vehicle, after self-admin0.20.41.70.30.50.50.6-0.30.7-1.0-1.30.2-0.3-0.1
Time to tail flick, test, before self-admin0.80.91.71.10.81.00.9-0.81.1-1.30.70.61.11.0
Time to tail flick, test, after self-admin1.01.02.7-1.10.50.20.4-0.10.5-1.40.91.51.61.4
Delta time to tail flick, vehicle, before/after SA0.80.92.41.50.90.90.9-0.90.5-0.9-1.4-0.3-0.8-0.3
Delta time to tail flick, test, before/after SA0.20.21.1-1.1-0.0-0.4-0.20.5-0.1-0.30.00.50.40.3
Tibia length0.10.30.7-0.8-0.7-0.8-0.70.5-0.7-0.3-0.10.50.20.1
Ambulatory time before self-admin0.51.42.6-0.21.10.81.1-0.50.9-1.51.41.61.51.6
Ambulatory time after self-admin3.04.88.11.62.72.62.5-2.02.8-2.21.71.22.22.0
Bone: tissue strength0.40.41.5-0.30.10.00.1-0.5-0.4-0.80.71.20.91.0
Total heroin consumption0.20.20.80.7-0.1-0.0-0.10.30.30.2-0.9-0.5-0.7-0.4
Bone: trabecular number1.63.05.62.12.32.22.4-1.81.5-1.71.00.61.31.3
Bone: trabecular spacing1.21.74.2-2.1-1.4-1.7-1.51.5-1.70.10.71.10.50.5
Bone: trabecular thickness1.41.95.92.41.91.82.0-1.60.7-0.5-0.8-0.8-0.5-0.4
Bone: trabecular tissue density0.61.03.01.71.11.21.0-0.91.0-0.1-0.7-1.1-0.7-0.6
Water consumed over 24 hours0.91.73.50.51.21.11.2-0.31.5-1.91.21.21.61.6
Number of responses in last shaping day0.30.31.3-0.0-0.2-0.2-0.10.4-0.61.10.0-1.0-0.5-0.8