Slc35g1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Slc35g1 0.34 0.17 9.7e-05 0.13 0.12 0.08 0.15 4.8e-04 1.2e-03 6.9e-03 2.0e-04
2 Eye mRNA stability Slc35g1 0.49 0.16 2.8e-04 0.02 0.06 0.01 0.02 1.4e-01 4.2e-02 2.1e-01 1.6e-01
3 LHb mRNA stability Slc35g1 0.21 0.11 2.4e-04 0.13 0.13 0.08 0.12 6.4e-04 6.1e-04 5.2e-03 9.7e-04
4 Brain gene expression Slc35g1 0.09 0.05 1.9e-07 0.08 0.08 0.07 0.07 1.3e-07 3.8e-08 2.8e-07 1.8e-07
5 Eye gene expression Slc35g1 0.36 0.19 7.5e-03 0.09 0.08 0.06 0.1 1.7e-02 2.4e-02 4.2e-02 1.2e-02
6 BLA gene expression Slc35g1 0.54 0.14 6.6e-04 -0 0.07 0.08 0.06 5.2e-01 8.0e-05 4.2e-05 3.3e-04
7 Liver gene expression Slc35g1 0.06 0.04 9.2e-05 0.02 0.03 0.03 0.03 2.0e-03 5.6e-04 4.6e-04 7.6e-04
8 pVTA gene expression Slc35g1 0.65 0.1 1.3e-05 0.11 0.14 0.14 0.15 2.1e-05 1.1e-06 1.7e-06 6.8e-07
9 PL gene expression Slc35g1 0.42 0.11 3.4e-07 0.05 0.07 0.09 0.07 1.2e-06 4.0e-08 1.3e-09 2.0e-08
10 NAcc gene expression Slc35g1 0.64 0.07 1.1e-16 0.11 0.16 0.16 0.15 6.4e-13 4.4e-18 2.0e-18 3.7e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.23.87.32.72.52.7-2.7-1.01.42.2-1.00.90.4
Area under the delay curve0.50.62.2-1.5-0.9-0.60.01.20.80.6-0.2-0.10.1
BMI with tail0.41.33.51.41.61.9-1.7-1.50.00.40.00.1-0.2
BMI without tail1.83.75.91.01.61.7-2.0-2.02.4-0.4-2.42.32.4
Body weight0.20.82.41.31.31.2-0.7-1.5-0.1-0.20.1-0.5-0.4
Weight adjusted by age0.30.30.7-0.8-0.20.4-0.8-0.20.40.50.9-0.6-0.5
Bone surface2.34.06.02.42.42.4-2.4-1.42.21.4-1.81.71.4
Bone volume1.93.36.52.62.32.4-2.3-1.71.51.3-1.21.00.8
Breakpoint value in progressive ratio session0.80.92.1-0.0-0.6-0.60.71.0-1.10.31.5-1.4-1.4
Number of licking bursts0.91.02.9-1.7-1.5-1.10.31.60.10.0-0.30.70.7
Context. condit. distance diff. score0.91.13.92.01.51.4-0.9-0.8-0.00.70.4-0.4-1.0
Locomotion velocity, session 11.41.63.8-1.9-1.7-1.50.61.90.70.6-0.60.90.9
Locomotion distance, session 10.70.81.4-0.7-1.1-0.90.81.0-1.20.11.1-0.9-0.9
Locomotion velocity, session 22.52.96.80.20.70.7-1.31.22.62.2-1.82.32.0
Locomotion distance, session 20.10.20.9-0.2-0.10.0-0.20.70.60.9-0.10.40.4
Locomotion velocity, session 30.20.30.70.80.70.6-0.4-0.40.60.4-0.30.10.1
Locomotion distance, session 30.60.62.31.50.90.50.1-1.2-0.6-0.4-0.0-0.5-0.7
Stereotopy head waving bouts, day 30.30.41.90.30.20.4-0.7-0.00.71.4-0.40.50.1
Stereotopy head waving duration, day 30.40.42.30.20.20.6-0.9-0.00.71.5-0.10.4-0.0
Locomotion velocity, session 71.92.14.42.12.01.8-1.6-2.11.20.9-0.70.40.3
Locomotion distance, session 71.51.93.41.81.81.5-1.3-1.91.30.2-1.11.00.9
Stereotopy head waving bouts, day 70.50.63.4-0.0-0.3-0.0-0.31.30.21.8-0.30.4-0.3
Stereotopy head waving duration, day 70.20.21.00.20.00.1-0.30.5-0.01.0-0.50.5-0.2
Locomotion velocity, session 80.30.30.80.70.70.7-0.6-0.10.00.90.4-0.3-0.6
Locomotion distance, session 80.71.02.91.31.11.3-1.00.20.41.70.8-0.5-0.9
Degree of sensitization distance0.40.40.9-0.10.20.5-0.80.21.00.8-0.30.70.7
Degree of sensitization stereotypy0.50.62.7-0.2-0.5-0.50.41.6-0.51.30.2-0.1-0.8
Conditioned locomotion1.01.12.60.30.40.30.1-1.3-1.1-1.61.2-1.5-1.3
Cocaine response after cond. corrected0.20.20.6-0.6-0.3-0.40.30.40.7-0.1-0.40.60.7
Cocaine response after cond. not corrected0.20.20.8-0.2-0.2-0.30.20.60.90.4-0.30.50.4
Cocaine response before conditioning0.20.20.90.4-0.00.0-0.00.70.30.90.1-0.1-0.5
Saline control response3.74.97.7-1.7-2.1-1.91.92.5-2.4-0.52.8-2.8-2.5
Bone: connectivity density3.86.011.12.82.93.2-3.3-1.32.42.1-2.12.01.5
Bone: cortical apparent density0.60.82.4-1.2-1.2-0.90.61.6-0.60.40.5-0.1-0.6
Bone: cortical area0.50.82.71.61.00.6-0.2-1.40.3-0.6-0.80.40.5
Bone: cortical porosity0.60.61.60.60.71.0-1.20.20.91.1-0.50.70.4
Bone: cortical porosity1.31.42.20.91.11.2-1.4-0.21.51.0-1.31.41.2
Bone: cortical thickness1.01.63.4-0.8-1.5-1.71.80.8-1.3-1.20.9-1.1-0.9
Bone: cortical thickness1.21.43.2-1.4-1.8-1.71.41.6-0.8-0.30.8-0.6-0.6
Bone: cortical tissue density0.50.72.4-1.2-1.2-0.80.51.6-0.50.50.5-0.0-0.5
Condit. Reinf. active minus inactive responses0.50.51.7-0.3-0.2-0.40.20.20.4-0.5-1.21.21.3
Condit. Reinf. active-inactive response ratio0.60.71.8-0.6-0.2-0.40.20.10.3-0.9-1.31.31.4
Condit. Reinf. active responses0.10.10.40.2-0.1-0.40.5-0.1-0.6-0.60.0-0.10.0
Condit. Reinf. inactive responses0.60.71.90.4-0.2-0.20.40.1-1.10.31.4-1.3-1.4
Incentive salience index mean0.40.51.1-0.8-0.8-1.01.00.6-0.3-0.8-0.10.20.5
Condit. Reinf. lever presses1.62.13.6-1.6-1.7-1.81.91.1-1.3-1.31.5-1.3-0.8
Condit. Reinf. active minus inactive responses1.61.93.51.81.81.9-1.8-1.80.90.9-0.70.70.5
Condit. Reinf. active-inactive response ratio0.91.02.10.91.21.4-1.5-1.10.70.9-0.50.70.4
Condit. Reinf. active responses0.60.82.31.40.80.7-0.3-1.5-0.7-0.50.7-0.9-0.9
Condit. Reinf. inactive responses1.72.03.60.2-0.8-1.21.7-0.2-1.9-1.91.5-1.9-1.6
Condit. Reinf. lever presses0.20.20.5-0.7-0.7-0.70.50.60.1-0.00.20.10.1
Condit. Reinf. lever reinforcers received0.30.51.10.90.50.4-0.1-1.0-0.6-0.40.7-0.9-0.8
Conditioned reinforcement - actives0.70.72.51.00.90.8-0.50.70.91.6-0.30.1-0.2
Conditioned reinforcement - inactives2.73.18.32.21.91.8-1.70.11.72.9-1.51.40.6
Conditioned locomotion0.10.10.50.70.1-0.10.30.3-0.20.2-0.10.1-0.1
Patch foraging indifference point 0 sec0.61.01.9-1.2-1.1-1.31.00.70.3-1.4-0.70.61.0
Patch foraging indifference point AUC2.73.17.1-1.9-2.5-2.52.22.7-1.2-0.41.0-0.6-0.5
Delay disc. indifference point, 0s delay1.01.02.90.41.11.4-1.7-0.11.51.2-0.40.50.4
Delay disc. indifference point, 16s delay0.50.52.0-0.9-0.8-0.70.41.40.10.8-0.1-0.3-0.2
Delay disc. indifference point, 2s delay0.30.41.5-0.8-0.30.2-0.80.31.20.5-0.20.40.5
Delay disc. indifference point, 24s delay0.80.82.1-1.1-1.2-1.31.01.5-0.40.30.3-0.2-0.1
Delay disc. indifference point, 4s delay0.60.62.3-1.1-0.8-0.4-0.01.50.61.10.3-0.2-0.1
Delay disc. indifference point, 8s delay1.71.88.1-2.8-2.0-1.60.81.40.5-0.20.1-0.30.2
Indifference point function ln k3.04.18.22.42.82.7-2.4-2.91.31.0-1.50.90.9
Indifference point function log k3.04.18.22.42.82.7-2.4-2.91.31.0-1.50.90.9
Patch foraging total patch changes 0 sec0.61.02.1-1.1-1.0-1.31.00.50.4-1.4-0.80.71.1
Patch foraging total patch changes 12 sec2.73.57.4-2.6-2.7-2.62.22.4-0.9-1.30.8-0.4-0.3
Patch foraging total patch changes 18 sec0.81.02.6-1.5-1.4-1.20.61.60.5-0.4-0.30.60.7
Patch foraging total patch changes 24 sec0.60.81.6-1.1-1.0-1.31.00.60.5-0.9-0.70.51.0
Patch foraging total patch changes 6 sec2.53.78.3-2.4-2.7-2.92.32.6-0.3-1.3-0.60.91.2
Patch foraging time to switch 0 sec0.60.91.6-1.3-1.2-0.80.61.1-0.7-0.41.3-0.8-1.0
Patch foraging water rate 0 sec1.01.72.41.31.51.2-1.1-1.21.50.9-1.61.21.3
Patch foraging water rate 12 sec0.50.71.40.91.10.7-0.5-1.01.00.2-1.20.80.9
Patch foraging water rate 18 sec1.62.13.61.21.61.3-1.2-1.31.91.3-1.81.31.4
Patch foraging water rate 24 sec0.50.61.30.91.11.0-0.8-1.10.70.5-0.60.40.5
Patch foraging water rate 6 sec0.10.20.40.20.40.3-0.3-0.60.50.2-0.60.50.5
Seeking ratio, delayed vs. immediate footshock0.50.51.30.3-0.3-0.50.80.3-0.7-0.90.7-1.1-1.1
Distance traveled before self-admin1.01.01.50.51.11.0-1.20.11.21.0-1.21.21.1
Distance traveled after self-admin3.23.56.21.41.82.1-2.5-0.22.02.3-1.82.11.7
Extensor digitorum longus weight0.31.43.11.61.00.9-0.3-0.9-1.0-0.01.3-1.6-1.8
Bone: elastic displacement0.40.50.9-0.8-0.10.3-1.0-0.40.5-0.2-0.80.90.9
Bone: elastic work1.11.42.8-0.00.61.0-1.7-0.61.50.9-1.31.51.4
Bone: endosteal estimation3.88.213.33.63.63.3-3.1-2.92.71.5-2.52.42.4
Bone: endosteal perimeter3.67.411.63.43.43.2-3.1-2.42.81.4-2.42.32.2
Epididymis fat weight0.61.36.80.71.11.1-1.0-2.60.5-1.30.0-0.4-0.0
Delta time in closed arm before/after self-admin0.50.51.8-0.1-0.6-0.91.1-0.7-0.1-1.4-0.60.10.4
Delta time in open arm before/after self-admin1.61.54.40.31.21.5-1.70.61.42.1-0.41.00.8
Diff in mean of infusions in LGA sessions2.02.23.41.21.61.4-1.5-1.11.81.0-1.71.61.5
Delay discount exponential model param0.60.72.41.51.00.7-0.1-1.3-0.8-0.60.20.0-0.2
Extinction: sum of active levers before priming0.10.10.50.70.2-0.10.4-0.30.1-0.3-0.1-0.10.2
Active lever presses in extinction session 62.22.15.91.71.72.1-2.1-0.40.52.40.10.3-0.1
Bone: final force0.10.10.80.90.3-0.00.3-0.10.20.2-0.20.30.3
Bone: final moment0.10.20.60.70.3-0.00.2-0.50.3-0.2-0.50.60.6
Food consumed during 24 hour testing period0.50.61.7-0.2-0.3-0.60.5-0.20.7-0.8-1.21.31.1
Glucose0.20.20.70.90.50.20.3-0.7-0.6-0.20.2-0.3-0.4
Heart weight0.91.32.8-0.4-0.8-1.31.2-0.30.7-1.7-1.51.31.5
Delay discount hyperbolic model param0.60.62.21.50.90.50.1-1.1-1.0-0.60.3-0.1-0.3
Intermittent access intake day 1-15 change3.23.24.81.72.21.9-1.8-0.72.00.9-2.12.01.8
Intermittent access intake escalation3.03.04.81.42.01.7-1.6-0.82.10.7-2.22.11.9
Intermittent access intake escalation 24.64.66.71.52.52.3-2.3-0.72.61.5-2.52.52.2
Intermitt. access day 1 inactive lever presses0.60.62.00.00.40.5-0.7-0.41.40.3-0.90.91.1
Intermitt. access day 15 inactive lever presses0.30.30.60.80.50.5-0.7-0.30.30.5-0.70.50.4
Intermitt. access escalation Index0.90.82.10.61.21.2-1.1-1.40.6-0.5-0.40.50.3
Intermittent access day 1 total infusions0.60.72.91.70.90.8-0.5-0.8-0.80.50.1-0.4-0.8
Intermittent access day 15 total infusions1.82.06.52.62.21.8-1.1-1.50.30.3-1.20.70.3
Intermittent access terminal intake (last 3 days)1.71.95.22.32.11.8-1.4-0.90.50.9-1.30.80.3
Intermittent access total infusions1.21.35.42.31.71.4-0.9-1.1-0.30.6-0.5-0.1-0.6
Intermittent access day 1 locomotion0.20.21.11.10.40.20.2-0.9-0.5-0.1-0.00.1-0.0
Intermittent access day 15 total locomotion0.40.41.40.4-0.4-0.50.70.8-1.20.20.6-0.6-0.7
Intermittent access total locomotion0.30.30.70.6-0.1-0.10.30.5-0.80.70.6-0.6-0.8
Intermittent access standard deviation3.53.76.81.92.31.8-1.6-1.12.01.0-2.62.32.0
Left kidney weight0.51.52.70.5-0.4-0.91.5-0.3-1.4-1.61.3-1.6-1.6
Right kidney weight1.23.37.8-0.4-1.6-2.22.80.4-2.1-2.41.3-1.8-1.6
Cocaine induced anxiety0.40.51.5-0.00.60.8-1.0-0.31.20.9-0.20.20.1
Post-drug Anxiety0.91.02.4-1.5-1.1-0.60.30.5-0.2-0.21.4-1.4-1.2
Baseline Anxiety0.90.91.8-1.1-1.3-1.21.10.3-1.0-1.10.7-0.7-0.3
Tail length0.41.33.30.60.5-0.10.1-1.11.7-0.8-1.81.21.7
Length with tail0.10.41.60.3-0.3-0.81.30.2-0.4-0.50.4-1.0-0.6
Length without tail1.63.58.50.6-0.4-0.71.51.1-2.50.52.7-2.9-2.9
Times rat made contact with spout0.70.83.3-0.00.40.7-1.2-0.11.81.0-0.70.60.6
Lifetime Intake0.80.94.22.01.11.0-0.5-0.7-0.90.4-0.0-0.4-0.9
Liver weight, left0.81.32.41.00.50.10.8-1.2-1.5-1.21.3-1.6-1.3
Liver weight, right0.60.92.10.60.3-0.10.8-0.8-1.2-1.01.3-1.4-1.2
Locomotor activity0.71.24.3-0.20.30.4-0.9-0.22.10.8-1.51.21.3
Locomotor testing distance1.42.48.3-0.50.40.4-1.1-0.02.91.2-2.21.82.0
Locomotor testing rearing0.71.01.91.11.31.3-1.30.01.41.3-0.80.30.4
Locomotion in novel chamber2.22.76.42.52.12.4-2.0-1.00.62.2-0.2-0.1-0.5
Locomotion in novel chamber post-restriction1.51.94.21.0-0.1-0.10.71.4-1.81.21.7-1.9-2.0
Fecal boli incidents, locomotor time 10.91.04.51.30.91.1-1.1-0.40.52.1-0.10.1-0.3
Change in fecal boli incidents, locomotor task0.90.81.3-0.8-0.9-1.01.11.0-0.7-1.11.1-0.6-0.4
Time >=10cm from walls, locomotor time 10.60.62.61.60.8-0.10.90.1-1.3-0.10.2-0.2-0.5
Bouts of movement, locomotor time 10.50.61.90.0-0.3-0.10.00.4-0.90.50.9-1.3-1.4
Total resting periods, locomotor time 10.70.82.1-0.1-0.4-0.20.21.0-0.90.91.0-1.3-1.4
Rest time, locomotor task time 10.80.84.20.00.30.8-1.20.91.12.10.1-0.3-0.4
Distance moved, locomotor task time 10.70.84.2-0.1-0.4-1.01.3-0.4-0.6-2.0-0.10.40.7
Vertical activity count, locomotor time 10.80.83.0-0.7-0.4-0.91.1-0.40.2-1.7-0.60.81.0
Time >=10cm from walls, locomotor time 20.20.20.80.30.70.3-0.20.10.30.1-0.90.40.3
Bouts of movement, locomotor time 21.41.65.9-2.0-1.6-1.30.62.40.60.80.1-0.10.0
Total resting periods, locomotor time 21.51.66.9-2.0-1.5-1.20.52.60.61.10.2-0.10.0
Rest time, locomotor task time 21.21.33.2-0.6-0.8-0.50.41.8-0.51.61.5-1.4-1.3
Distance moved, locomotor task time 21.01.13.71.11.00.5-0.1-1.70.1-1.9-1.00.80.8
Vertical activity count, locomotor time 22.22.46.8-0.30.60.3-0.5-1.11.8-1.0-2.62.32.4
Light reinforcement 10.30.51.4-0.2-0.6-0.20.20.4-0.80.41.0-1.2-1.2
Light reinforcement 20.60.82.7-1.6-1.4-0.80.31.1-0.50.60.7-0.4-0.6
Bone: marrow area3.88.213.73.73.73.4-3.1-2.92.61.5-2.52.42.3
Bone: maximum diameter3.56.414.73.83.53.3-2.9-2.51.81.2-1.71.51.2
Bone: maximum force0.50.93.31.81.21.0-0.7-0.70.40.9-0.60.70.4
Bone: maximum moment0.50.92.71.61.10.9-0.7-1.10.50.5-0.91.00.8
Mean time between licks in bursts0.40.61.2-1.0-0.4-0.70.7-0.10.6-1.1-1.00.81.1
Mean num. licks in bursts1.41.73.81.81.91.7-1.3-1.91.20.6-0.40.0-0.0
Cd content in liver1.51.66.4-1.2-1.4-1.71.60.2-1.0-2.5-0.40.20.3
Co content in liver0.91.12.9-1.6-0.9-0.90.4-0.70.6-1.7-1.10.81.1
Cu content in liver3.34.011.3-3.4-2.9-2.51.63.2-0.5-0.01.0-0.7-0.4
Fe content in liver1.21.44.5-2.1-1.6-1.51.11.5-0.4-0.50.5-0.5-0.3
K content in liver0.90.92.4-0.5-0.30.00.11.3-0.70.81.6-1.4-1.3
Mg content in liver0.91.02.5-1.2-0.9-0.70.61.6-0.50.51.3-1.1-0.9
Mn content in liver2.22.55.8-1.9-1.8-1.41.12.4-1.01.61.7-1.0-1.3
Na content in liver2.83.06.7-1.0-1.2-0.91.11.8-2.10.82.6-2.2-2.4
Rb content in liver0.10.10.20.20.30.2-0.2-0.20.30.5-0.0-0.2-0.1
Se content in liver10.512.837.4-6.1-5.3-4.83.64.9-1.0-0.41.4-0.6-0.3
Sr content in liver0.20.20.60.20.1-0.10.1-0.00.1-0.5-0.70.80.6
Zn content in liver1.21.34.5-2.1-1.5-1.40.81.10.5-1.0-0.50.61.0
Bone: minimum diameter4.58.519.84.44.13.4-2.7-3.62.10.7-2.32.01.7
Time in familiar zone, hab. session 10.40.30.80.00.20.5-0.9-0.60.70.6-0.70.70.6
Time in novel zone, hab. session 10.20.21.0-0.4-0.4-0.60.51.0-0.3-0.20.10.10.1
Total zone transitions, hab. session 10.20.30.9-0.1-0.10.1-0.00.6-0.40.61.0-0.9-0.9
Total locomotion distance, hab. session 11.01.42.4-1.2-1.3-1.10.91.3-1.0-0.11.5-1.4-1.2
Locomotion velocity, hab. session 11.92.64.2-1.6-1.8-1.61.51.5-1.5-0.32.0-1.9-1.7
Time in familiar zone, hab. session 20.60.61.2-0.9-0.6-0.50.1-0.70.7-1.1-1.00.71.0
Time in novel zone, hab. session 20.10.10.40.30.10.00.20.6-0.60.40.4-0.1-0.4
Total zone transitions, hab. session 20.70.91.2-0.8-1.1-1.11.10.9-0.9-0.91.0-0.9-0.7
Total locomotion distance, hab. session 20.81.11.8-0.9-1.4-1.31.20.4-1.2-1.10.9-1.0-0.7
Locomotion velocity, hab. session 21.01.42.1-1.0-1.4-1.31.20.8-1.4-0.81.3-1.3-1.0
Novel to familiar place preference ratio4.54.610.01.41.92.2-2.60.12.83.2-1.82.31.7
Novelty place preference4.94.910.01.42.02.3-2.70.12.93.2-1.92.41.8
Time in novel zone, NPP test5.25.39.41.42.02.3-2.70.03.03.1-2.22.72.1
Total zone transitions, NPP test1.01.42.2-0.8-1.2-1.31.50.6-1.5-0.81.4-1.3-1.0
Total locomotion distance, NPP test1.42.03.5-1.6-1.9-1.81.61.3-1.2-0.61.4-1.2-0.9
Locomotion velocity, NPP test1.62.23.2-1.3-1.8-1.81.81.4-1.3-0.51.8-1.5-1.3
Intraocular pressure0.10.20.60.1-0.8-0.50.30.4-0.6-0.30.3-0.2-0.3
Delta distance traveled before/after self-admin1.01.12.61.21.21.5-1.6-0.90.91.1-0.40.70.6
Delta ambulatory time before/after self-admin1.61.83.81.81.71.9-1.8-1.20.81.2-0.30.60.3
Parametrial fat weight0.91.73.60.6-0.3-0.71.4-0.7-1.9-1.71.2-1.7-1.7
Pavlov. Cond. lever latency0.00.10.2-0.1-0.3-0.20.0-0.2-0.2-0.4-0.30.30.1
Pavlov. Cond. magazine entry latency0.81.11.8-1.1-0.8-1.21.10.31.0-1.2-1.00.91.3
Pavlov. Cond. change in total contacts0.91.02.9-0.20.1-0.30.3-0.41.0-0.6-1.61.61.7
Pavlov. Cond. index score0.20.30.6-0.6-0.5-0.80.80.50.4-0.5-0.20.20.5
Pavlov. Cond. latency score0.20.20.6-0.5-0.4-0.70.80.50.2-0.40.1-0.20.1
Pavlov. Cond. lever contacts0.40.51.0-0.5-0.6-0.81.00.5-0.5-0.41.0-1.0-0.6
Pavlov. Cond. magazine entry number0.91.23.10.50.10.5-0.40.7-1.31.21.6-1.4-1.8
Pavlov. Cond. intertrial magazine entries0.30.41.00.2-0.1-0.10.2-0.1-1.00.20.9-0.9-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.30.6-0.8-0.5-0.80.80.40.5-0.6-0.30.30.6
Pavlov. Cond. response bias0.80.92.5-0.9-0.3-0.80.7-0.11.2-1.0-1.11.11.6
Pavlov. Cond. lever latency1.01.43.41.81.61.8-1.4-0.9-0.01.10.1-0.3-0.6
Pavlov. Cond. magazine entry latency0.70.82.1-0.3-0.0-0.40.2-0.51.2-0.6-1.51.31.4
Pavlov. Cond. change in total contacts0.30.41.0-1.0-0.8-1.00.80.30.2-0.7-0.10.20.4
Pavlov. Cond. index score0.50.61.4-1.1-0.9-1.21.00.40.4-0.6-0.40.50.7
Pavlov. Cond. latency score0.30.41.0-0.8-0.7-1.00.80.30.5-0.4-0.50.60.7
Pavlov. Cond. lever contacts0.81.12.7-1.5-1.5-1.61.40.9-0.2-1.10.3-0.20.2
Pavlov. Cond. magazine entry number0.91.23.11.51.41.8-1.6-0.50.21.20.1-0.0-0.3
Pavlov. Cond. intertrial magazine entries0.60.82.01.41.21.4-1.2-0.9-0.20.5-0.0-0.0-0.2
Pavlov. Cond. lever-magazine prob. diff.0.50.61.1-1.0-0.8-1.10.80.40.6-0.4-0.60.80.9
Pavlov. Cond. response bias0.91.22.8-1.6-1.4-1.71.30.80.3-1.1-0.40.50.9
Time in closed arm before self-admin1.41.63.70.71.21.5-1.9-0.31.51.6-1.11.10.9
Time in closed arm after self-admin0.10.10.5-0.1-0.4-0.40.30.0-0.0-0.20.4-0.7-0.5
Time in open arm before self-admin0.30.31.1-0.6-0.5-0.40.4-0.7-0.3-1.00.5-0.6-0.4
Time in open arm after self-admin0.30.30.9-0.30.40.6-0.70.70.70.9-0.00.50.5
Bone: periosteal estimation2.14.410.23.22.82.4-2.0-2.31.71.0-1.61.51.4
Bone: periosteal perimeter2.33.89.23.02.62.4-2.0-2.21.50.6-1.41.21.1
Bone: post-yield work0.91.24.92.21.31.1-0.8-1.0-0.00.2-1.01.00.7
Progressive ratio test 1 active lever presses0.80.82.11.50.91.0-0.7-0.5-0.90.70.4-0.7-1.1
Progressive ratio test 1 breakpoint0.70.71.91.41.01.1-0.8-0.5-0.60.70.2-0.6-1.0
Progressive ratio test 1 inactive lever presses2.02.14.22.11.92.0-1.9-1.50.91.2-1.10.60.3
Progressive ratio test 2 active lever presses1.51.65.42.31.71.6-1.3-0.8-0.41.4-0.3-0.0-0.6
Progressive ratio test 2 breakpoint1.82.06.52.61.91.9-1.6-0.8-0.31.6-0.4-0.0-0.7
Progressive ratio test 2 inactive lever presses1.31.53.51.91.51.7-1.6-0.3-0.11.8-0.40.2-0.4
Incentive Sensitization - Responses2.72.75.42.32.22.1-2.0-1.11.01.7-1.31.10.5
Incentive Sensitization - Breakpoint2.32.35.32.32.11.9-1.8-1.00.81.6-1.20.90.3
Sum of active levers in priming session hrs 5-60.90.92.6-0.5-0.00.0-0.5-0.51.2-0.0-1.21.51.6
Progressive ratio0.80.92.70.1-0.2-0.30.6-1.3-0.9-1.60.8-1.2-0.9
Food seeking constrained by brief footshock0.20.31.21.10.2-0.40.70.40.1-0.7-0.30.30.3
Seeking ratio, punishment vs. effort0.91.12.40.10.1-0.2-0.01.51.30.8-1.21.51.5
Retroperitoneal fat weight0.31.14.50.30.1-0.10.4-1.8-1.0-2.10.7-1.1-0.8
Reaction time number correct1.52.14.41.01.92.1-2.0-1.41.91.6-0.30.00.1
Reaction time mean minus median0.91.23.30.60.70.10.0-1.50.5-1.2-1.81.51.4
Reaction time mean minus median AUC0.60.82.2-0.00.4-0.00.0-1.50.4-1.2-1.41.01.1
Reaction time num false alarms0.30.40.80.3-0.3-0.50.90.1-0.8-0.20.9-0.9-0.7
Reaction time num false alarms AUC0.10.20.80.2-0.3-0.60.9-0.0-0.3-0.40.5-0.5-0.2
Reaction time trials correct on left1.52.14.41.01.92.1-2.0-1.41.91.6-0.30.00.1
Reaction time trials on left1.42.04.21.01.92.1-2.0-1.51.81.5-0.30.00.1
Reaction time mean0.91.34.9-0.7-0.9-1.41.3-0.20.1-2.2-1.20.91.1
Reaction time mean AUC1.01.44.6-0.9-1.1-1.51.50.0-0.2-2.1-0.90.80.9
Median of all reaction times0.91.24.5-0.9-1.1-1.51.30.1-0.0-2.1-0.80.70.9
Reaction time omissions1.92.57.00.81.10.5-0.3-2.71.1-1.9-2.31.71.7
Reaction time false alarm rate0.91.33.2-0.2-1.2-1.51.80.6-1.5-1.00.9-0.8-0.6
Reaction time premature initiation rate0.60.82.1-0.5-0.6-1.11.5-0.0-0.9-1.20.6-1.0-0.7
Reaction time premature initiations0.20.31.10.20.40.10.4-0.9-0.1-0.40.5-1.1-0.8
Std. dev. reaction times1.52.26.2-0.2-0.0-0.80.8-1.60.7-2.5-2.21.71.9
Reaction time trials completed1.42.04.21.01.92.1-2.0-1.51.81.5-0.30.00.1
Reaction time trials AUC1.31.93.80.91.71.9-1.9-1.41.91.5-0.30.10.1
Run reversals in cocaine runway, females0.60.51.6-0.7-0.5-0.2-0.30.41.30.3-0.51.01.1
Run reversals in cocaine runway, males3.33.25.9-0.8-1.7-1.82.11.9-2.4-0.72.0-1.7-1.8
Latency to leave start box in cocaine runway1.71.84.62.01.71.7-1.4-2.10.9-0.6-0.60.20.2
Latency to leave start box in cocaine runway, F2.32.56.42.52.22.2-1.9-2.01.00.1-0.80.40.3
Latency to leave start box in cocaine runway, M0.50.51.8-0.00.20.1-0.1-1.30.9-1.2-0.50.30.5
Std. dev. time between licks in bursts1.82.25.2-1.9-1.9-1.81.60.5-1.4-2.30.7-0.8-0.4
Total sessions with >9 infusions0.40.50.90.8-0.3-0.20.40.8-1.00.40.8-0.8-0.9
Short access day 1 total inactive lever presses1.61.84.51.71.52.1-2.1-1.00.21.7-0.1-0.0-0.6
Short access day 10 total inactive lever presses0.30.31.5-1.0-0.10.1-0.6-0.21.20.2-0.40.20.3
Short access day 1 total infusions1.21.23.40.4-0.6-0.40.60.5-1.8-0.21.5-1.6-1.9
Short access day 10 total infusions0.50.62.00.5-0.4-0.60.8-0.3-1.3-1.40.0-0.5-0.5
Short access total infusions0.60.71.71.30.10.20.10.2-1.30.10.7-1.0-1.3
Short access day 1 locomotion0.30.31.00.40.00.3-0.20.3-0.30.61.0-0.7-0.7
Short access day 10 total locomotion0.10.10.20.1-0.0-0.0-0.0-0.40.10.40.00.40.3
Short access total locomotion0.10.10.4-0.4-0.5-0.30.10.60.20.20.3-0.00.1
One hour access (0.3 mA shock)3.74.311.93.53.02.7-2.2-1.30.92.4-1.10.6-0.1
Compulsive drug intake1.91.93.91.52.01.6-1.4-1.81.50.2-1.31.00.8
One hour access (shock baseline)0.60.72.21.51.21.1-0.8-0.40.30.9-0.60.30.1
Social response proportion2.12.34.51.41.82.1-2.1-1.21.31.6-1.01.30.9
Social responses0.40.51.11.10.91.0-0.8-0.50.10.8-0.00.30.1
Social time0.30.40.9-0.7-0.7-0.70.90.9-0.60.00.7-0.2-0.2
Soleus weight0.72.03.91.91.91.8-1.7-2.01.00.7-0.80.50.6
Bone: stiffness0.81.26.02.51.41.1-0.4-0.7-0.41.00.3-0.6-0.9
Tibialis anterior weight0.51.64.32.11.61.6-1.1-0.7-0.41.00.9-1.2-1.4
Time to tail flick, vehicle, before self-admin0.50.51.6-1.3-0.9-0.3-0.30.90.11.20.5-0.3-0.4
Time to tail flick, vehicle, after self-admin0.30.40.80.60.80.7-0.6-0.50.90.80.2-0.20.2
Time to tail flick, test, before self-admin2.02.04.72.21.81.8-1.5-0.61.11.8-0.70.80.6
Time to tail flick, test, after self-admin2.62.77.6-0.40.91.2-2.0-0.62.81.0-1.91.82.1
Delta time to tail flick, vehicle, before/after SA1.01.03.61.91.61.2-0.7-1.10.60.30.10.00.1
Delta time to tail flick, test, before/after SA0.30.31.0-0.9-0.20.0-0.5-0.11.0-0.2-0.60.40.6
Tibia length0.10.30.7-0.8-0.5-0.80.80.20.6-0.1-0.30.10.5
Ambulatory time before self-admin1.01.02.00.10.80.7-1.10.31.40.7-1.41.41.3
Ambulatory time after self-admin5.46.010.32.22.52.8-3.2-0.42.43.1-2.12.51.9
Bone: tissue strength0.20.20.70.30.30.1-0.0-0.9-0.0-0.6-0.50.50.5
Total heroin consumption0.40.51.40.4-0.3-0.40.60.3-1.20.10.9-0.9-1.0
Bone: trabecular number2.64.16.32.32.32.3-2.5-1.01.91.6-2.12.11.6
Bone: trabecular spacing1.21.53.3-1.5-1.5-1.81.80.2-0.8-1.60.4-0.7-0.2
Bone: trabecular thickness1.61.94.52.11.91.9-1.7-1.50.90.8-0.80.60.3
Bone: trabecular tissue density0.50.61.51.20.91.0-0.7-0.3-0.40.70.6-0.7-0.9
Water consumed over 24 hours1.41.73.50.81.01.1-1.5-0.41.90.8-1.71.61.4
Number of responses in last shaping day1.61.65.51.00.50.7-0.3-0.7-1.6-0.11.5-1.9-2.4