Slc35g1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Slc35g1 0.34 0.18 1.5e-04 0.15 0.1 0.08 0.17 2.3e-04 1.9e-03 6.8e-03 9.1e-05
2 Eye mRNA stability Slc35g1 0.49 0.16 1.9e-04 0.08 0.09 0.06 0.13 2.2e-02 2.0e-02 4.0e-02 4.7e-03
3 LHb mRNA stability Slc35g1 0.19 0.11 4.6e-04 0.09 0.12 0.09 0.12 3.4e-03 8.7e-04 3.4e-03 1.1e-03
4 Brain gene expression Slc35g1 0.1 0.06 5.1e-08 0.09 0.09 0.08 0.08 7.6e-09 2.2e-08 4.0e-08 3.6e-08
5 Eye gene expression Slc35g1 0.39 0.2 5.5e-03 0.08 0.11 0.07 0.12 2.7e-02 9.5e-03 2.9e-02 6.9e-03
6 Liver gene expression Slc35g1 0.06 0.04 7.0e-05 0.02 0.03 0.03 0.02 2.6e-03 5.2e-04 4.2e-04 1.9e-03
7 BLA gene expression Slc35g1 0.52 0.15 1.7e-03 0 0.03 0.03 0.04 3.2e-01 7.7e-03 8.8e-03 2.7e-03
8 NAcc gene expression Slc35g1 0.56 0.04 0.0e+00 0.16 0.2 0.22 0.21 2.3e-23 3.9e-30 2.3e-32 7.1e-31
9 pVTA gene expression Slc35g1 0.63 0.04 4.4e-14 0.13 0.18 0.2 0.2 1.6e-10 8.4e-15 3.1e-16 3.3e-16
10 PL gene expression Slc35g1 0.45 0.11 3.6e-07 0.02 0.08 0.08 0.08 1.0e-03 9.6e-09 1.8e-09 7.7e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.44.27.62.72.72.7-2.8-2.2-2.0-1.50.1-0.7-0.7
Area under the delay curve0.20.31.0-1.0-0.4-0.40.30.9-0.5-0.2-0.2-0.2-0.1
BMI with tail0.20.61.41.00.71.2-0.8-1.1-0.90.10.40.00.1
BMI without tail0.20.51.9-0.5-0.4-0.20.40.10.3-0.7-1.4-1.0-1.1
Body weight0.10.42.11.50.30.4-0.3-0.70.4-0.20.50.90.6
Weight adjusted by age0.20.30.90.30.40.4-0.3-0.2-0.10.50.90.61.0
Bone surface2.34.16.32.52.42.5-2.4-2.5-1.9-1.9-0.7-1.2-1.2
Bone volume2.13.77.82.82.52.5-2.6-2.4-1.4-1.50.0-0.5-0.5
Breakpoint value in progressive ratio session0.20.30.90.1-0.3-0.30.20.6-0.50.20.60.90.7
Number of licking bursts0.60.93.2-1.8-1.1-1.01.11.3-0.10.1-0.5-0.5-0.3
Context. condit. distance diff. score1.72.06.32.51.31.5-1.4-1.4-1.20.11.61.10.8
Locomotion velocity, session 10.91.03.4-1.6-1.1-1.21.21.8-0.10.4-0.1-0.1-0.2
Locomotion distance, session 11.62.04.50.2-1.0-0.80.91.4-0.11.82.11.92.0
Locomotion velocity, session 24.14.810.7-1.00.70.8-0.8-0.4-2.5-3.1-3.0-3.1-3.3
Locomotion distance, session 20.10.21.40.1-0.30.10.20.2-1.2-0.20.20.40.2
Locomotion velocity, session 30.20.20.50.70.60.6-0.7-0.2-0.4-0.50.10.0-0.1
Locomotion distance, session 30.50.52.21.50.50.4-0.6-0.50.50.30.90.80.6
Stereotopy head waving bouts, day 30.91.03.0-0.50.50.4-0.60.0-0.6-1.3-1.3-1.7-1.5
Stereotopy head waving duration, day 30.70.92.1-0.50.50.5-0.5-0.3-1.2-1.1-1.0-1.4-1.3
Locomotion velocity, session 72.22.46.12.51.81.8-1.9-2.2-0.9-0.31.10.60.5
Locomotion distance, session 71.31.64.72.21.31.5-1.5-2.1-0.7-0.40.50.30.2
Stereotopy head waving bouts, day 70.40.41.0-0.40.4-0.0-0.40.8-0.8-0.7-0.3-1.0-1.0
Stereotopy head waving duration, day 70.30.30.9-0.20.60.1-0.50.5-0.2-0.6-0.3-0.9-1.0
Locomotion velocity, session 80.40.51.31.10.50.7-0.5-0.3-1.10.11.00.60.4
Locomotion distance, session 81.31.94.91.91.01.4-1.0-1.1-2.20.11.61.10.9
Degree of sensitization distance0.30.31.80.20.30.6-0.4-0.7-1.3-0.5-0.2-0.2-0.2
Degree of sensitization stereotypy0.20.21.4-0.4-0.1-0.50.11.2-0.4-0.00.2-0.3-0.4
Conditioned locomotion0.20.31.3-0.20.10.0-0.1-0.71.20.50.20.40.6
Cocaine response after cond. corrected1.01.23.4-1.4-0.5-0.40.5-0.0-0.4-1.0-1.8-1.6-1.5
Cocaine response after cond. not corrected0.91.12.8-1.1-0.3-0.30.20.1-0.8-1.2-1.7-1.5-1.5
Cocaine response before conditioning0.20.20.60.60.20.1-0.20.7-0.70.10.80.50.3
Saline control response2.02.66.3-1.1-1.6-1.61.62.50.51.61.51.81.8
Bone: connectivity density3.65.79.32.63.03.0-3.0-2.6-1.9-2.3-1.0-1.7-1.7
Bone: cortical apparent density0.30.41.2-0.6-0.7-0.50.71.1-0.20.80.70.10.2
Bone: cortical area1.32.07.42.70.90.8-0.9-1.00.50.51.71.91.5
Bone: cortical porosity1.61.74.40.81.21.5-1.1-1.2-2.1-1.4-0.7-1.2-1.2
Bone: cortical porosity1.82.03.20.91.31.4-1.2-1.3-1.8-1.8-1.1-1.5-1.5
Bone: cortical thickness2.33.98.60.5-1.4-1.41.41.41.62.42.52.92.8
Bone: cortical thickness3.44.08.10.4-1.4-1.41.41.90.72.42.82.82.7
Bone: cortical tissue density0.30.41.1-0.7-0.6-0.50.61.1-0.30.80.6-0.00.1
Condit. Reinf. active minus inactive responses0.00.00.1-0.1-0.2-0.30.00.30.2-0.1-0.20.0-0.1
Condit. Reinf. active-inactive response ratio0.30.30.8-0.7-0.3-0.40.00.40.6-0.4-0.9-0.6-0.8
Condit. Reinf. active responses0.20.30.90.4-0.3-0.30.20.30.50.60.60.90.8
Condit. Reinf. inactive responses0.60.82.10.7-0.3-0.10.30.1-0.11.11.41.51.4
Incentive salience index mean0.50.61.0-0.5-1.0-1.00.80.90.90.70.30.80.7
Condit. Reinf. lever presses1.92.64.0-1.3-2.0-1.81.81.51.61.90.91.61.6
Condit. Reinf. active minus inactive responses1.51.93.51.91.81.9-1.9-1.7-0.9-0.90.1-0.5-0.4
Condit. Reinf. active-inactive response ratio1.01.12.10.91.31.5-1.4-1.3-0.9-0.7-0.3-0.8-0.7
Condit. Reinf. active responses0.71.02.81.70.70.6-0.7-0.50.50.61.31.21.2
Condit. Reinf. inactive responses1.92.44.80.3-1.2-1.31.21.31.91.71.62.22.0
Condit. Reinf. lever presses0.30.41.2-0.9-0.6-0.70.61.10.3-0.0-0.4-0.2-0.3
Condit. Reinf. lever reinforcers received0.50.81.71.30.40.4-0.4-0.20.50.81.31.21.2
Conditioned reinforcement - actives0.40.72.00.60.60.5-0.80.3-1.1-1.4-0.4-0.9-0.9
Conditioned reinforcement - inactives1.62.34.61.31.51.3-1.6-0.8-1.9-2.1-0.7-1.7-1.7
Conditioned locomotion0.10.20.50.50.1-0.1-0.10.40.2-0.6-0.3-0.7-0.7
Patch foraging indifference point 0 sec0.61.22.1-1.4-1.2-1.41.01.41.5-0.0-1.0-0.3-0.3
Patch foraging indifference point AUC2.02.86.6-1.5-2.2-2.32.22.61.01.10.61.10.9
Delay disc. indifference point, 0s delay1.11.33.30.61.81.5-1.7-0.6-1.5-0.9-0.1-0.6-0.3
Delay disc. indifference point, 16s delay0.20.21.1-0.2-0.7-0.60.41.1-0.40.3-0.00.20.3
Delay disc. indifference point, 2s delay0.20.20.5-0.60.20.2-0.10.0-0.4-0.5-0.5-0.7-0.7
Delay disc. indifference point, 24s delay0.60.71.8-0.9-1.3-1.21.21.3-0.10.2-0.10.20.0
Delay disc. indifference point, 4s delay0.20.20.9-0.7-0.3-0.20.20.9-0.80.00.10.00.2
Delay disc. indifference point, 8s delay1.21.45.0-2.2-1.4-1.51.31.60.50.3-0.3-0.10.1
Indifference point function ln k1.93.36.52.12.42.4-2.5-2.6-0.9-1.3-0.3-0.7-0.9
Indifference point function log k1.93.36.52.12.42.4-2.5-2.6-0.9-1.3-0.3-0.7-0.9
Patch foraging total patch changes 0 sec0.71.32.5-1.5-1.1-1.40.91.51.6-0.1-1.1-0.3-0.4
Patch foraging total patch changes 12 sec3.14.09.0-2.6-2.5-2.72.43.01.51.3-0.20.30.5
Patch foraging total patch changes 18 sec0.71.02.7-1.6-1.1-1.31.11.60.50.1-0.6-0.2-0.3
Patch foraging total patch changes 24 sec0.50.91.9-1.4-0.9-1.40.91.21.2-0.3-0.60.0-0.1
Patch foraging total patch changes 6 sec2.94.410.4-2.7-2.6-2.92.63.21.60.5-0.9-0.1-0.2
Patch foraging time to switch 0 sec0.30.72.4-1.6-1.1-0.91.20.8-0.20.4-0.4-0.4-0.2
Patch foraging water rate 0 sec0.51.22.61.21.51.2-1.6-1.2-0.3-1.2-0.4-0.6-0.6
Patch foraging water rate 12 sec0.20.41.11.10.90.7-0.8-0.7-0.3-0.80.00.1-0.2
Patch foraging water rate 18 sec0.81.32.61.61.31.3-1.5-1.3-1.1-1.2-0.1-0.3-0.3
Patch foraging water rate 24 sec0.40.61.30.90.80.9-0.9-1.2-0.5-1.00.00.1-0.3
Patch foraging water rate 6 sec0.10.10.40.60.30.4-0.4-0.4-0.2-0.00.50.40.2
Seeking ratio, delayed vs. immediate footshock0.20.20.60.1-0.1-0.50.30.20.80.30.30.70.5
Distance traveled before self-admin1.11.42.50.11.21.0-1.2-0.7-1.2-1.6-1.4-1.3-1.5
Distance traveled after self-admin2.42.94.70.81.91.8-1.8-1.4-2.2-1.8-1.3-2.0-1.7
Extensor digitorum longus weight0.41.85.62.40.91.0-0.7-1.2-0.30.61.71.71.4
Bone: elastic displacement0.30.31.3-0.80.40.2-0.4-0.20.20.0-0.7-1.1-0.7
Bone: elastic work0.50.61.40.61.21.0-1.2-0.7-0.8-0.20.1-0.6-0.3
Bone: endosteal estimation3.78.113.63.53.43.4-3.4-3.7-2.3-3.0-1.0-1.4-1.7
Bone: endosteal perimeter3.26.915.23.93.43.4-3.3-3.3-2.2-1.90.2-0.1-0.5
Epididymis fat weight0.72.35.02.21.61.6-1.6-1.90.50.61.71.21.3
Delta time in closed arm before/after self-admin0.70.61.5-0.8-0.9-0.90.90.51.2-0.3-0.9-0.3-0.6
Delta time in open arm before/after self-admin1.71.75.40.51.41.5-1.4-0.8-2.3-1.1-0.8-1.2-1.1
Diff in mean of infusions in LGA sessions1.11.32.00.91.41.4-1.4-1.2-1.0-1.3-0.8-0.8-0.9
Delay discount exponential model param0.30.31.31.10.50.5-0.4-0.90.50.30.30.30.2
Extinction: sum of active levers before priming0.10.10.40.6-0.4-0.30.40.00.4-0.5-0.40.1-0.2
Active lever presses in extinction session 63.73.610.02.32.12.5-2.1-2.0-3.2-1.30.3-0.3-0.4
Bone: final force0.20.31.51.20.10.2-0.1-0.4-0.1-0.20.30.70.4
Bone: final moment0.10.21.11.00.10.2-0.1-0.50.1-0.3-0.10.30.2
Food consumed during 24 hour testing period0.30.40.9-0.4-0.6-0.60.50.50.3-0.5-1.0-0.8-0.9
Glucose0.00.10.40.60.20.1-0.2-0.00.3-0.10.00.2-0.0
Heart weight0.71.15.0-0.7-1.0-1.10.90.02.2-0.0-1.2-0.6-0.6
Delay discount hyperbolic model param0.30.31.41.20.40.4-0.3-0.80.40.40.50.50.4
Intermittent access intake day 1-15 change1.12.33.21.11.81.6-1.7-1.7-1.0-1.7-1.4-1.2-1.7
Intermittent access intake escalation1.42.84.91.62.22.0-2.1-1.9-1.1-1.6-1.1-1.0-1.5
Intermittent access intake escalation 24.04.56.71.22.62.4-2.4-2.1-1.9-2.4-1.8-1.9-2.3
Intermitt. access day 1 inactive lever presses0.20.71.9-0.50.60.5-0.6-0.3-0.7-0.9-1.2-1.4-1.1
Intermitt. access day 15 inactive lever presses0.40.71.91.41.10.9-1.3-0.6-0.1-0.70.0-0.7-0.5
Intermitt. access escalation Index0.20.30.6-0.30.70.3-0.7-0.80.40.40.80.30.2
Intermittent access day 1 total infusions0.50.82.81.71.01.0-1.0-0.5-0.8-0.30.9-0.00.0
Intermittent access day 15 total infusions1.42.16.32.51.91.8-2.0-1.7-0.6-0.80.5-0.2-0.5
Intermittent access terminal intake (last 3 days)1.72.25.42.32.01.8-2.0-1.5-1.1-0.90.4-0.4-0.7
Intermittent access total infusions1.11.35.32.31.31.3-1.4-0.9-0.5-0.11.30.30.2
Intermittent access day 1 locomotion0.30.41.71.30.50.8-0.5-0.7-0.4-0.00.5-0.2-0.1
Intermittent access day 15 total locomotion0.10.31.01.00.10.2-0.00.1-0.60.50.80.30.4
Intermittent access total locomotion0.80.93.41.90.71.0-0.7-0.6-1.30.11.20.30.3
Intermittent access standard deviation1.83.86.71.61.91.7-1.8-1.5-1.5-2.5-1.9-2.1-2.6
Left kidney weight0.10.40.80.3-0.9-0.80.80.40.80.00.40.70.3
Right kidney weight0.41.93.7-0.4-1.8-1.91.81.51.80.80.71.31.0
Cocaine induced anxiety0.81.12.60.31.61.5-1.6-1.4-0.9-0.6-0.0-0.5-0.3
Post-drug Anxiety0.40.51.5-0.60.1-0.0-0.1-0.41.21.10.40.70.9
Baseline Anxiety1.51.84.3-0.9-1.7-1.61.60.82.11.40.21.01.0
Tail length0.10.41.50.1-0.0-0.50.10.31.0-1.2-0.9-0.3-0.5
Length with tail0.10.41.21.0-0.2-0.60.30.30.8-0.40.61.10.6
Length without tail0.72.46.72.60.70.8-0.7-1.1-1.00.42.32.11.8
Times rat made contact with spout1.21.42.9-0.60.70.6-0.6-0.2-1.0-1.7-1.6-1.7-1.6
Lifetime Intake0.91.14.82.21.11.1-1.2-0.6-0.40.01.30.30.3
Liver weight, left0.50.92.50.6-0.8-0.60.70.10.90.81.21.61.2
Liver weight, right0.30.51.00.90.70.7-0.8-0.9-0.4-1.0-0.3-0.4-0.3
Locomotor activity0.60.92.1-0.30.80.3-0.90.0-0.3-1.4-1.2-1.4-1.2
Locomotor testing distance0.61.12.9-0.60.70.2-0.80.4-0.5-1.6-1.4-1.7-1.4
Locomotor testing rearing0.61.22.61.21.61.2-1.6-0.6-1.2-1.2-0.3-0.8-0.5
Locomotion in novel chamber2.83.66.82.42.22.6-2.2-2.4-2.5-0.90.6-0.40.1
Locomotion in novel chamber post-restriction1.01.63.41.5-0.6-0.10.70.6-0.91.31.81.71.9
Fecal boli incidents, locomotor time 10.81.22.51.41.21.3-1.4-1.1-1.6-0.90.5-0.2-0.4
Change in fecal boli incidents, locomotor task1.11.11.7-0.8-1.0-1.21.21.31.31.00.51.00.8
Time >=10cm from walls, locomotor time 10.20.20.80.9-0.1-0.20.3-0.1-0.1-0.10.60.90.4
Bouts of movement, locomotor time 10.70.82.90.70.1-0.1-0.30.4-0.10.91.71.41.5
Total resting periods, locomotor time 10.80.93.00.60.0-0.2-0.30.7-0.50.81.71.31.4
Rest time, locomotor task time 10.30.41.50.30.80.4-1.20.1-1.2-0.00.70.00.3
Distance moved, locomotor task time 10.50.82.4-0.6-1.1-0.91.40.51.60.1-0.80.00.0
Vertical activity count, locomotor time 10.30.81.7-1.1-1.0-0.91.30.31.3-0.1-1.1-0.3-0.4
Time >=10cm from walls, locomotor time 20.10.10.40.00.60.1-0.5-0.2-0.3-0.6-0.2-0.0-0.3
Bouts of movement, locomotor time 20.60.93.4-1.6-0.9-1.10.91.8-0.4-0.2-0.1-0.2-0.2
Total resting periods, locomotor time 20.50.93.7-1.5-0.8-1.00.91.9-0.6-0.3-0.0-0.1-0.1
Rest time, locomotor task time 20.70.92.60.0-0.3-0.30.21.0-1.10.71.61.41.3
Distance moved, locomotor task time 20.40.41.40.40.50.3-0.2-1.01.2-0.5-0.9-0.6-0.3
Vertical activity count, locomotor time 21.62.37.6-1.20.30.1-0.3-0.80.4-1.5-2.8-2.3-2.2
Light reinforcement 10.20.51.1-0.1-0.7-0.50.60.8-0.11.01.00.50.9
Light reinforcement 20.61.01.7-1.2-1.0-0.91.11.2-0.61.31.10.30.7
Bone: marrow area3.88.414.13.53.53.5-3.5-3.8-2.3-3.0-1.0-1.5-1.7
Bone: maximum diameter4.17.721.64.63.63.5-3.5-3.4-1.8-1.31.20.60.2
Bone: maximum force0.81.56.52.51.11.4-1.1-1.1-1.0-0.50.90.70.4
Bone: maximum moment0.71.25.22.31.11.3-1.1-1.2-0.8-0.70.40.30.1
Mean time between licks in bursts0.30.83.6-1.0-0.7-1.00.60.81.90.3-0.6-0.0-0.1
Mean num. licks in bursts1.11.73.01.71.71.6-1.7-1.7-0.7-1.1-0.3-0.4-0.6
Cd content in liver0.80.91.9-1.4-1.1-1.31.11.11.10.4-0.5-0.3-0.4
Co content in liver2.22.68.1-2.2-1.5-1.91.61.32.80.6-1.2-0.7-0.5
Cu content in liver2.83.310.2-3.2-2.2-2.22.12.60.30.7-0.7-0.4-0.2
Fe content in liver1.41.74.2-2.0-1.7-1.71.61.70.81.0-0.10.20.3
K content in liver0.20.21.9-0.3-0.20.00.00.2-1.4-0.00.30.10.2
Mg content in liver0.20.21.2-0.6-0.6-0.30.30.2-1.10.20.20.20.3
Mn content in liver1.61.72.9-0.7-1.3-0.71.41.3-1.71.41.71.21.3
Na content in liver0.60.71.2-0.7-1.1-0.80.91.0-0.70.90.60.60.6
Rb content in liver0.10.10.20.10.30.2-0.5-0.5-0.1-0.5-0.2-0.4-0.2
Se content in liver12.114.343.1-6.6-4.9-4.84.94.80.91.4-1.8-0.9-0.7
Sr content in liver0.20.10.3-0.4-0.4-0.40.40.5-0.4-0.1-0.2-0.3-0.4
Zn content in liver2.22.48.4-2.9-1.6-1.61.31.30.0-0.4-1.8-1.5-1.2
Bone: minimum diameter4.37.817.24.13.53.3-3.5-3.8-1.1-2.5-0.6-0.8-1.3
Time in familiar zone, hab. session 10.30.20.70.10.60.6-0.4-0.5-0.2-0.3-0.4-0.8-0.6
Time in novel zone, hab. session 10.20.20.5-0.6-0.6-0.60.50.7-0.1-0.2-0.4-0.1-0.2
Total zone transitions, hab. session 10.40.51.40.6-0.00.2-0.10.4-0.90.61.20.91.0
Total locomotion distance, hab. session 10.81.12.6-1.0-1.2-1.11.01.6-0.11.10.70.81.0
Locomotion velocity, hab. session 11.72.44.7-1.3-1.8-1.61.62.20.31.71.21.41.6
Time in familiar zone, hab. session 20.40.42.8-0.4-0.3-0.60.40.51.70.40.30.30.4
Time in novel zone, hab. session 20.10.10.8-0.1-0.00.1-0.0-0.0-0.9-0.2-0.4-0.4-0.4
Total zone transitions, hab. session 21.51.94.10.2-1.1-0.91.11.10.61.61.82.02.0
Total locomotion distance, hab. session 21.52.03.4-0.3-1.4-1.31.41.41.21.71.41.71.8
Locomotion velocity, hab. session 21.62.13.8-0.4-1.5-1.31.51.40.91.71.51.82.0
Novel to familiar place preference ratio6.16.711.60.62.42.3-2.4-1.8-3.4-3.4-2.3-3.0-3.0
Novelty place preference6.36.811.70.72.42.4-2.4-1.8-3.4-3.4-2.2-3.0-3.0
Time in novel zone, NPP test6.46.811.90.72.52.4-2.5-1.8-3.3-3.5-2.3-3.0-3.1
Total zone transitions, NPP test1.62.34.8-0.0-1.4-1.11.31.20.71.81.82.22.2
Total locomotion distance, NPP test2.12.94.6-1.0-1.9-1.71.92.10.91.81.51.91.9
Locomotion velocity, NPP test2.02.84.1-0.9-1.9-1.71.92.00.81.71.51.91.9
Intraocular pressure0.20.30.8-0.3-0.7-0.50.70.90.60.50.40.20.2
Delta distance traveled before/after self-admin0.80.91.81.11.21.4-1.0-1.2-1.1-0.40.0-0.6-0.2
Delta ambulatory time before/after self-admin1.11.42.81.71.51.7-1.3-1.6-1.1-0.40.4-0.4-0.1
Parametrial fat weight0.51.32.5-0.6-1.3-1.41.21.11.60.80.71.30.9
Pavlov. Cond. lever latency0.20.20.8-0.30.2-0.00.10.10.3-0.6-0.7-0.8-0.9
Pavlov. Cond. magazine entry latency0.50.71.5-1.0-1.1-1.21.00.80.9-0.0-0.7-0.2-0.3
Pavlov. Cond. change in total contacts0.20.20.7-0.4-0.5-0.40.10.10.3-0.3-0.8-0.6-0.7
Pavlov. Cond. index score0.20.30.7-0.5-0.9-0.80.60.60.30.40.10.40.4
Pavlov. Cond. latency score0.20.30.6-0.2-0.7-0.60.50.60.30.50.30.50.6
Pavlov. Cond. lever contacts0.40.50.9-0.3-0.9-0.60.60.40.20.90.60.90.9
Pavlov. Cond. magazine entry number0.30.30.80.60.50.6-0.5-0.0-0.60.20.90.70.6
Pavlov. Cond. intertrial magazine entries0.60.72.20.4-0.2-0.10.00.20.21.01.31.51.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.6-0.8-0.80.60.60.30.40.00.30.3
Pavlov. Cond. response bias0.30.40.9-0.8-0.7-0.70.50.20.4-0.2-0.9-0.5-0.5
Pavlov. Cond. lever latency1.41.84.52.11.61.6-1.6-1.6-0.90.21.40.70.8
Pavlov. Cond. magazine entry latency1.51.85.4-1.7-0.7-0.80.70.30.5-1.1-2.3-1.7-1.8
Pavlov. Cond. change in total contacts0.40.71.6-1.3-1.0-1.11.00.90.80.0-0.9-0.2-0.3
Pavlov. Cond. index score1.21.63.7-1.9-1.2-1.31.31.10.7-0.5-1.7-0.9-1.1
Pavlov. Cond. latency score1.01.32.9-1.7-1.0-1.11.10.90.5-0.7-1.7-1.0-1.2
Pavlov. Cond. lever contacts1.41.94.4-2.1-1.7-1.81.71.71.20.2-1.1-0.3-0.4
Pavlov. Cond. magazine entry number1.72.15.22.31.71.8-1.6-1.4-1.3-0.01.50.60.7
Pavlov. Cond. intertrial magazine entries1.11.64.62.21.51.6-1.5-1.3-0.60.11.20.70.7
Pavlov. Cond. lever-magazine prob. diff.1.11.53.4-1.9-1.1-1.21.11.00.6-0.7-1.8-1.1-1.3
Pavlov. Cond. response bias1.62.15.1-2.2-1.6-1.71.61.51.3-0.2-1.7-0.8-0.9
Time in closed arm before self-admin0.70.91.60.91.31.1-1.2-0.7-1.2-0.9-0.3-0.9-0.5
Time in closed arm after self-admin0.20.20.50.1-0.3-0.40.40.40.70.30.20.50.7
Time in open arm before self-admin0.30.41.4-0.4-0.5-0.40.4-0.11.20.90.40.60.5
Time in open arm after self-admin0.30.31.2-0.30.30.5-0.40.1-1.1-0.5-0.5-0.5-0.6
Bone: periosteal estimation2.34.914.13.82.72.7-2.7-2.9-1.4-1.60.40.2-0.2
Bone: periosteal perimeter2.44.113.13.62.52.5-2.5-2.5-1.0-0.71.00.80.4
Bone: post-yield work1.01.45.82.41.11.5-1.2-1.2-0.9-1.10.20.1-0.4
Progressive ratio test 1 active lever presses0.81.03.41.80.50.7-0.60.0-0.80.61.71.00.9
Progressive ratio test 1 breakpoint0.80.92.81.70.30.5-0.40.3-0.60.71.71.11.0
Progressive ratio test 1 inactive lever presses0.81.12.51.61.31.3-1.4-0.6-1.2-1.00.2-0.7-0.3
Progressive ratio test 2 active lever presses1.92.25.32.32.01.8-2.0-0.9-1.8-1.00.9-0.1-0.1
Progressive ratio test 2 breakpoint2.02.35.62.42.11.8-2.1-0.9-1.7-1.00.9-0.1-0.0
Progressive ratio test 2 inactive lever presses0.91.43.01.71.61.5-1.7-0.5-1.6-0.50.7-0.4-0.1
Incentive Sensitization - Responses2.23.15.51.52.42.0-2.3-1.5-2.1-2.2-0.4-1.2-1.2
Incentive Sensitization - Breakpoint2.12.85.11.52.31.9-2.2-1.4-2.0-2.1-0.2-1.0-1.1
Sum of active levers in priming session hrs 5-61.11.13.1-1.5-0.4-0.60.40.30.5-0.6-1.8-1.4-1.3
Progressive ratio0.50.82.7-0.4-0.6-0.70.70.11.61.10.71.11.2
Food seeking constrained by brief footshock0.10.20.40.4-0.2-0.40.30.60.3-0.70.10.40.1
Seeking ratio, punishment vs. effort0.70.92.7-0.4-0.1-0.20.10.8-0.9-1.7-1.3-1.2-1.4
Retroperitoneal fat weight0.20.92.30.3-0.5-0.50.50.11.51.01.31.41.2
Reaction time number correct1.42.75.41.82.12.2-2.1-2.3-1.8-0.90.70.30.2
Reaction time mean minus median0.51.13.0-0.30.3-0.0-0.3-0.71.0-1.2-1.7-1.5-1.7
Reaction time mean minus median AUC0.51.33.7-1.00.3-0.1-0.2-0.71.2-1.1-1.9-1.6-1.7
Reaction time num false alarms0.20.31.10.4-0.6-0.50.40.50.60.10.51.00.7
Reaction time num false alarms AUC0.10.20.6-0.0-0.6-0.60.40.60.8-0.4-0.20.40.1
Reaction time trials correct on left1.42.75.41.82.12.2-2.1-2.3-1.8-0.90.70.30.2
Reaction time trials on left1.42.65.41.82.12.1-2.1-2.3-1.7-0.90.70.30.2
Reaction time mean1.42.24.2-1.7-1.3-1.51.10.82.0-0.7-2.1-1.5-1.5
Reaction time mean AUC1.42.34.1-1.9-1.6-1.61.51.02.0-0.4-1.8-1.2-1.3
Median of all reaction times1.41.93.2-1.7-1.4-1.61.31.01.8-0.5-1.7-1.2-1.2
Reaction time omissions0.91.32.9-0.30.50.1-0.5-1.31.1-1.1-1.7-1.6-1.6
Reaction time false alarm rate0.91.32.6-0.8-1.5-1.51.41.61.50.2-0.30.30.2
Reaction time premature initiation rate0.50.71.5-0.7-1.1-1.21.11.21.1-0.1-0.10.30.2
Reaction time premature initiations0.10.10.50.40.0-0.1-0.1-0.10.3-0.30.60.70.5
Std. dev. reaction times1.22.25.7-1.3-0.5-0.90.5-0.12.3-1.2-2.4-1.8-1.9
Reaction time trials completed1.42.65.41.82.12.1-2.1-2.3-1.7-0.90.70.30.2
Reaction time trials AUC1.32.45.01.62.02.0-2.0-2.2-1.7-0.90.70.30.3
Run reversals in cocaine runway, females0.60.61.2-1.0-0.5-0.40.60.6-0.3-0.9-1.0-0.8-1.1
Run reversals in cocaine runway, males3.13.14.8-1.0-2.1-1.92.12.21.11.91.51.81.6
Latency to leave start box in cocaine runway1.11.22.91.51.51.4-1.4-1.70.50.00.50.20.5
Latency to leave start box in cocaine runway, F1.71.93.92.02.01.9-1.9-2.0-0.2-0.30.40.00.3
Latency to leave start box in cocaine runway, M0.10.10.7-0.10.20.1-0.2-0.50.8-0.0-0.2-0.1-0.1
Std. dev. time between licks in bursts1.92.64.3-2.1-2.1-1.92.01.62.01.70.00.60.7
Total sessions with >9 infusions0.20.21.00.1-0.4-0.30.41.00.20.50.60.20.6
Short access day 1 total inactive lever presses1.62.24.42.11.72.1-1.8-1.6-1.80.11.0-0.30.0
Short access day 10 total inactive lever presses0.10.10.4-0.60.50.0-0.4-0.0-0.0-0.5-0.4-0.30.0
Short access day 1 total infusions0.30.41.30.3-0.5-0.30.31.0-0.10.91.20.50.8
Short access day 10 total infusions0.60.71.90.1-0.8-0.90.71.41.01.00.90.50.6
Short access total infusions0.30.41.61.30.40.5-0.50.3-0.50.21.10.20.3
Short access day 1 locomotion0.10.20.80.30.20.6-0.30.1-0.90.20.3-0.30.0
Short access day 10 total locomotion0.10.10.4-0.3-0.5-0.10.5-0.0-0.7-0.1-0.1-0.4-0.4
Short access total locomotion0.20.20.7-0.2-0.20.00.20.4-0.6-0.1-0.3-0.9-0.5
One hour access (0.3 mA shock)3.43.97.32.72.62.4-2.6-1.8-2.1-1.80.3-0.7-0.9
Compulsive drug intake0.70.82.00.51.41.1-1.4-1.3-0.1-0.9-0.2-0.5-0.6
One hour access (shock baseline)0.30.41.81.40.60.6-0.6-0.3-0.7-0.40.50.20.1
Social response proportion2.22.54.92.11.92.2-2.0-2.2-1.7-0.00.80.00.2
Social responses0.50.72.21.50.61.1-0.9-1.0-0.60.50.70.30.4
Social time0.30.51.1-0.4-1.1-0.60.90.60.21.00.10.60.6
Soleus weight0.82.46.12.01.82.0-1.8-2.5-1.0-1.3-0.3-0.7-0.5
Bone: stiffness1.32.29.53.11.21.4-1.2-1.1-0.9-0.31.61.41.0
Tibialis anterior weight0.61.95.02.21.71.7-1.6-1.6-1.3-0.50.90.50.5
Time to tail flick, vehicle, before self-admin0.30.30.9-0.9-0.3-0.10.30.7-1.00.30.4-0.10.3
Time to tail flick, vehicle, after self-admin0.20.31.10.30.50.5-0.6-0.3-0.7-1.0-0.20.30.1
Time to tail flick, test, before self-admin0.91.01.71.10.81.0-0.9-0.8-1.1-1.3-0.6-1.1-1.0
Time to tail flick, test, after self-admin1.01.12.7-1.10.50.2-0.4-0.1-0.5-1.4-1.5-1.7-1.4
Delta time to tail flick, vehicle, before/after SA0.80.82.41.50.90.9-0.9-0.9-0.5-0.90.30.80.3
Delta time to tail flick, test, before/after SA0.20.21.1-1.1-0.0-0.40.20.50.1-0.3-0.5-0.4-0.3
Tibia length0.10.30.7-0.8-0.7-0.80.70.50.7-0.3-0.5-0.2-0.1
Ambulatory time before self-admin0.91.42.6-0.21.10.8-1.1-0.5-0.9-1.5-1.6-1.5-1.6
Ambulatory time after self-admin4.25.08.11.62.72.6-2.5-2.0-2.8-2.1-1.2-2.2-2.0
Bone: tissue strength0.40.41.5-0.20.10.0-0.1-0.50.4-0.8-1.2-0.9-1.0
Total heroin consumption0.10.20.50.7-0.1-0.00.10.3-0.30.20.50.70.4
Bone: trabecular number1.93.25.62.12.32.2-2.4-1.8-1.5-1.7-0.6-1.3-1.3
Bone: trabecular spacing1.41.84.2-2.1-1.4-1.71.51.51.70.1-1.1-0.5-0.5
Bone: trabecular thickness1.72.15.92.41.91.8-2.0-1.6-0.7-0.50.80.50.4
Bone: trabecular tissue density0.71.13.01.71.11.2-1.0-0.9-1.0-0.11.10.70.6
Water consumed over 24 hours1.31.73.50.51.21.1-1.2-0.3-1.5-1.9-1.2-1.6-1.6
Number of responses in last shaping day0.30.41.3-0.0-0.2-0.20.10.40.61.11.00.50.8