Hub : Genes

Slc30a3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Slc30a3 0.24 0.16 2.9e-04 0.11 0.11 0.11 0.1 1.5e-03 1.5e-03 1.1e-03 2.1e-03
2 Liver mRNA stability Slc30a3 0.04 0.04 1.9e-04 0.02 0.02 0.02 0.02 9.0e-04 2.1e-03 1.3e-03 1.9e-03
3 BLA gene expression Slc30a3 0.1 0.07 1.7e-05 0.1 0.09 0.1 0.1 7.3e-06 1.3e-05 7.5e-06 7.5e-06
4 PL gene expression Slc30a3 0.07 0.05 1.3e-10 0.09 0.1 0.09 0.09 1.8e-10 5.8e-11 2.7e-10 2.8e-10
5 Liver gene expression Slc30a3 0.81 0.14 0.0e+00 0.22 0.22 0.22 0.22 1.9e-24 9.9e-24 1.7e-24 5.4e-24
6 IC gene expression Slc30a3 0.14 0.08 3.3e-07 0.12 0.15 0.11 0.14 7.0e-06 8.7e-07 2.9e-05 2.6e-06
7 Brain gene expression Slc30a3 0.08 0.05 8.4e-10 0.08 0.09 0.08 0.08 7.5e-08 1.3e-08 3.4e-08 4.7e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density4.37.39.82.3-1.93.12.9-2.92.82.8
Area under the delay curve0.10.10.40.1-0.30.70.3-0.40.30.3
BMI with tail0.72.47.5-2.12.7-0.9-1.11.0-1.0-1.0
BMI without tail1.03.06.4-2.12.5-1.5-1.51.4-1.4-1.4
Body weight2.510.813.1-3.63.5-3.1-3.23.2-3.1-3.1
Weight adjusted by age0.10.10.20.5-0.10.10.3-0.40.30.3
Bone surface2.13.95.81.4-0.82.42.2-2.32.12.0
Bone volume2.24.05.81.5-1.12.42.2-2.22.12.1
Breakpoint value in progressive ratio session0.70.81.20.7-0.31.10.9-1.11.01.0
Number of licking bursts0.20.41.5-1.01.20.50.1-0.20.10.1
Context. condit. distance diff. score0.00.00.20.2-0.4-0.10.00.00.00.0
Locomotion velocity, session 10.10.10.4-0.60.3-0.2-0.10.2-0.1-0.2
Locomotion distance, session 11.51.82.31.0-1.11.51.5-1.51.41.4
Locomotion velocity, session 20.20.30.3-0.50.5-0.5-0.50.6-0.6-0.5
Locomotion distance, session 20.00.00.00.10.1-0.00.1-0.00.00.0
Locomotion velocity, session 30.70.71.11.0-0.60.60.9-0.91.01.0
Locomotion distance, session 30.60.70.90.7-0.20.90.9-0.90.90.9
Stereotopy head waving bouts, day 31.92.22.91.7-1.11.31.5-1.51.61.6
Stereotopy head waving duration, day 30.10.20.30.5-0.30.20.4-0.40.50.5
Locomotion velocity, session 70.91.01.50.60.21.11.1-1.21.21.1
Locomotion distance, session 70.20.31.1-0.71.10.00.2-0.30.20.2
Stereotopy head waving bouts, day 70.00.00.10.20.30.20.1-0.00.10.1
Stereotopy head waving duration, day 70.40.51.31.1-0.70.60.6-0.50.60.7
Locomotion velocity, session 80.30.30.70.9-0.60.20.5-0.60.50.4
Locomotion distance, session 80.30.40.50.6-0.70.50.7-0.60.60.6
Degree of sensitization distance1.21.22.2-1.51.4-1.0-0.90.9-0.9-1.0
Degree of sensitization stereotypy0.20.20.4-0.30.6-0.3-0.50.6-0.5-0.4
Conditioned locomotion3.43.95.02.2-2.21.81.9-1.91.91.9
Cocaine response after cond. corrected0.50.60.80.2-0.40.90.9-0.90.90.8
Cocaine response after cond. not corrected1.41.62.40.9-1.01.61.4-1.41.31.3
Cocaine response before conditioning2.02.43.92.0-2.01.51.3-1.31.31.3
Saline control response0.70.91.51.2-1.00.91.0-0.90.90.9
Bone: connectivity density3.96.28.32.1-1.42.92.7-2.72.72.6
Bone: cortical apparent density0.40.51.10.2-0.31.10.8-0.80.80.8
Bone: cortical area0.50.71.10.20.11.01.0-1.00.90.9
Bone: cortical porosity1.81.93.61.9-1.91.21.2-1.11.11.1
Bone: cortical porosity1.71.93.01.7-1.71.21.2-1.21.21.2
Bone: cortical thickness0.00.10.3-0.50.60.10.00.0-0.1-0.1
Bone: cortical thickness1.21.41.80.9-0.61.31.3-1.31.31.3
Bone: cortical tissue density0.30.40.80.0-0.20.90.6-0.70.60.6
Condit. Reinf. active minus inactive responses1.01.12.3-1.51.5-0.7-0.90.8-0.8-0.9
Condit. Reinf. active-inactive response ratio1.01.01.9-1.31.4-0.7-1.00.9-0.9-0.9
Condit. Reinf. active responses0.10.10.4-0.20.10.60.3-0.30.40.4
Condit. Reinf. inactive responses1.51.92.41.2-1.31.51.4-1.31.41.4
Incentive salience index mean0.10.10.4-0.60.60.30.1-0.10.10.1
Condit. Reinf. lever presses0.60.91.50.6-0.71.21.0-1.00.90.9
Condit. Reinf. active minus inactive responses3.84.96.42.5-2.22.02.2-2.12.22.3
Condit. Reinf. active-inactive response ratio1.11.21.91.4-1.40.91.0-0.91.01.1
Condit. Reinf. active responses3.24.45.42.3-1.92.12.1-2.02.12.2
Condit. Reinf. inactive responses1.41.82.31.2-0.71.51.4-1.51.51.4
Condit. Reinf. lever presses2.23.03.71.9-1.91.61.7-1.71.61.7
Condit. Reinf. lever reinforcers received2.94.05.02.2-1.82.02.0-2.02.02.0
Conditioned reinforcement - actives1.83.17.82.4-2.81.01.4-1.51.31.3
Conditioned reinforcement - inactives2.74.05.41.5-1.82.32.1-2.12.12.0
Conditioned locomotion0.50.72.21.3-1.5-0.30.3-0.50.30.3
Patch foraging indifference point 0 sec0.40.81.3-1.01.1-0.5-0.90.9-0.8-0.8
Patch foraging indifference point AUC0.91.42.00.2-0.01.41.4-1.41.41.3
Delay disc. indifference point, 0s delay2.62.93.4-1.81.3-1.4-1.81.7-1.8-1.8
Delay disc. indifference point, 16s delay0.10.20.40.3-0.60.60.3-0.30.30.3
Delay disc. indifference point, 2s delay0.10.20.3-0.60.2-0.3-0.40.4-0.4-0.4
Delay disc. indifference point, 24s delay1.41.63.11.1-1.81.51.0-1.11.01.1
Delay disc. indifference point, 4s delay0.00.00.1-0.30.20.20.1-0.20.10.1
Delay disc. indifference point, 8s delay0.10.10.20.2-0.30.50.2-0.30.20.2
Indifference point function ln k0.20.31.21.0-1.10.00.1-0.10.10.1
Indifference point function log k0.20.31.21.0-1.10.00.1-0.10.10.1
Patch foraging total patch changes 0 sec0.40.81.6-1.11.2-0.4-0.80.8-0.8-0.8
Patch foraging total patch changes 12 sec1.31.72.7-1.71.6-0.9-1.21.2-1.1-1.1
Patch foraging total patch changes 18 sec0.30.41.8-0.91.3-0.1-0.30.3-0.3-0.3
Patch foraging total patch changes 24 sec0.81.31.6-1.31.2-1.1-1.11.1-1.1-1.1
Patch foraging total patch changes 6 sec0.40.62.0-1.11.4-0.0-0.40.4-0.3-0.4
Patch foraging time to switch 0 sec0.10.10.7-0.40.8-0.3-0.20.2-0.1-0.1
Patch foraging water rate 0 sec0.10.31.20.9-1.10.20.2-0.20.10.1
Patch foraging water rate 12 sec0.71.62.5-0.40.1-1.6-1.41.4-1.5-1.4
Patch foraging water rate 18 sec0.50.81.10.5-1.0-1.0-0.90.9-0.9-0.9
Patch foraging water rate 24 sec1.82.53.9-0.81.0-2.0-1.81.7-1.8-1.7
Patch foraging water rate 6 sec0.91.31.9-0.2-0.3-1.4-1.31.3-1.4-1.3
Seeking ratio, delayed vs. immediate footshock0.00.00.20.0-0.0-0.5-0.20.2-0.2-0.2
Distance traveled before self-admin0.10.10.60.4-0.8-0.4-0.00.1-0.2-0.1
Distance traveled after self-admin2.02.43.8-1.41.1-1.9-1.51.6-1.6-1.6
Extensor digitorum longus weight4.317.018.74.1-3.44.34.3-4.24.24.2
Bone: elastic displacement0.91.02.51.1-1.60.80.8-0.80.80.9
Bone: elastic work1.01.21.71.0-1.31.11.1-1.11.11.1
Bone: endosteal estimation0.51.21.80.7-0.21.21.2-1.31.21.2
Bone: endosteal perimeter0.20.50.80.3-0.20.80.8-0.90.80.7
Epididymis fat weight16.857.659.9-7.77.5-7.6-7.77.5-7.5-7.6
Delta time in closed arm before/after self-admin0.20.20.9-0.51.0-0.10.1-0.10.10.1
Delta time in open arm before/after self-admin0.10.10.10.2-0.20.30.3-0.30.40.4
Diff in mean of infusions in LGA sessions0.00.00.1-0.10.30.40.1-0.20.10.1
Delay discount exponential model param0.40.40.8-0.40.6-0.9-0.60.7-0.6-0.7
Extinction: sum of active levers before priming0.30.30.6-0.00.30.80.5-0.60.60.6
Active lever presses in extinction session 60.60.61.21.1-0.80.50.7-0.80.80.8
Bone: final force0.10.10.2-0.20.10.20.4-0.50.40.3
Bone: final moment0.10.10.3-0.10.00.30.5-0.50.50.4
Food consumed during 24 hour testing period0.10.20.20.20.00.50.5-0.40.50.4
Glucose0.30.51.1-0.91.0-0.6-0.60.5-0.6-0.6
Heart weight3.04.75.1-2.32.0-2.2-2.12.2-2.2-2.2
Delay discount hyperbolic model param0.20.20.5-0.10.3-0.7-0.50.5-0.5-0.5
Intermittent access intake day 1-15 change0.10.20.90.9-0.8-0.20.3-0.20.20.2
Intermittent access intake escalation0.00.10.30.5-0.5-0.40.00.1-0.1-0.1
Intermittent access intake escalation 20.00.00.10.30.0-0.30.10.1-0.1-0.1
Intermitt. access day 1 inactive lever presses0.41.51.71.2-1.31.11.3-1.21.31.2
Intermitt. access day 15 inactive lever presses3.06.17.91.8-1.72.52.8-2.72.82.7
Intermitt. access escalation Index1.31.98.0-1.62.8-0.9-0.60.7-0.6-0.6
Intermittent access day 1 total infusions3.45.56.42.4-2.52.42.3-2.32.32.3
Intermittent access day 15 total infusions1.72.53.71.9-1.91.41.5-1.41.41.4
Intermittent access terminal intake (last 3 days)2.73.65.62.3-2.41.61.8-1.71.71.7
Intermittent access total infusions2.93.56.32.3-2.51.61.6-1.61.61.6
Intermittent access day 1 locomotion1.92.43.11.5-1.81.51.5-1.51.51.5
Intermittent access day 15 total locomotion0.20.30.40.5-0.60.60.5-0.70.50.5
Intermittent access total locomotion0.40.51.00.8-1.00.70.5-0.70.60.5
Intermittent access standard deviation0.91.83.11.3-1.81.21.3-1.31.31.2
Left kidney weight0.00.00.10.0-0.2-0.4-0.20.2-0.2-0.2
Right kidney weight0.41.82.3-1.40.9-1.1-1.51.5-1.4-1.4
Cocaine induced anxiety0.20.30.5-0.10.40.70.5-0.60.60.5
Post-drug Anxiety1.41.52.4-1.61.4-0.8-1.21.1-1.1-1.2
Baseline Anxiety2.93.34.0-1.71.3-1.9-2.01.9-2.0-2.0
Tail length0.41.42.2-0.80.3-1.5-1.31.3-1.4-1.3
Length with tail1.66.99.6-2.01.3-3.1-2.92.9-2.9-2.9
Length without tail0.61.82.5-1.10.8-1.6-1.41.4-1.4-1.4
Times rat made contact with spout1.61.92.41.1-0.71.51.5-1.51.51.5
Lifetime Intake3.03.65.82.3-2.41.71.7-1.81.71.7
Liver weight, left3.66.06.5-2.42.2-2.4-2.62.6-2.5-2.5
Liver weight, right9.316.318.5-3.83.2-4.2-4.24.3-4.2-4.2
Locomotor activity0.50.82.0-1.41.3-0.3-0.70.6-0.6-0.6
Locomotor testing distance0.20.30.8-0.40.90.40.4-0.40.50.5
Locomotor testing rearing0.40.71.10.8-0.30.60.9-1.01.11.1
Locomotion in novel chamber0.20.31.10.10.1-1.0-0.50.5-0.4-0.4
Locomotion in novel chamber post-restriction3.04.95.2-2.22.2-2.3-2.32.2-2.2-2.1
Fecal boli incidents, locomotor time 10.40.51.41.2-1.10.40.6-0.40.50.5
Change in fecal boli incidents, locomotor task4.34.35.1-2.21.9-2.0-2.12.0-2.1-2.1
Time >=10cm from walls, locomotor time 10.10.10.20.1-0.5-0.2-0.30.3-0.3-0.2
Bouts of movement, locomotor time 11.51.72.31.1-0.51.51.5-1.51.41.4
Total resting periods, locomotor time 11.82.02.51.2-0.71.61.6-1.61.51.5
Rest time, locomotor task time 10.00.00.10.0-0.2-0.2-0.20.2-0.2-0.2
Distance moved, locomotor task time 10.81.31.5-1.11.0-1.2-1.11.2-1.1-1.0
Vertical activity count, locomotor time 10.20.50.6-0.70.7-0.7-0.70.8-0.7-0.7
Time >=10cm from walls, locomotor time 20.40.61.70.8-1.30.60.5-0.70.50.4
Bouts of movement, locomotor time 20.10.10.2-0.50.3-0.2-0.20.1-0.3-0.3
Total resting periods, locomotor time 20.00.00.0-0.20.10.10.2-0.20.10.0
Rest time, locomotor task time 21.21.52.11.0-0.81.41.3-1.31.31.3
Distance moved, locomotor task time 20.91.11.3-0.90.6-1.1-1.11.1-1.1-1.1
Vertical activity count, locomotor time 20.30.50.6-0.50.4-0.8-0.80.8-0.8-0.8
Light reinforcement 12.35.77.51.8-0.92.72.7-2.62.72.6
Light reinforcement 22.74.15.21.8-1.52.32.2-2.12.12.1
Bone: marrow area0.51.21.80.7-0.21.21.2-1.31.21.2
Bone: maximum diameter0.91.72.50.60.11.51.5-1.61.51.4
Bone: maximum force0.10.20.30.2-0.30.30.5-0.60.50.5
Bone: maximum moment0.20.30.40.3-0.40.50.6-0.60.60.6
Mean time between licks in bursts1.63.84.1-1.91.9-1.9-2.02.0-2.0-1.9
Mean num. licks in bursts0.30.51.61.2-1.30.20.5-0.40.40.5
Cd content in liver0.00.00.2-0.10.40.00.1-0.10.10.1
Co content in liver5.96.87.72.4-2.42.82.7-2.72.62.6
Cu content in liver0.20.20.70.5-0.80.30.3-0.20.30.3
Fe content in liver1.11.32.91.3-1.70.81.0-0.91.11.1
K content in liver0.30.30.4-0.40.30.70.7-0.70.60.6
Mg content in liver0.40.40.5-0.50.30.70.7-0.70.70.6
Mn content in liver0.30.31.4-0.61.20.00.2-0.30.30.2
Na content in liver0.80.92.51.1-1.60.60.8-0.70.70.7
Rb content in liver0.10.10.6-0.60.80.00.0-0.00.10.1
Se content in liver0.10.20.3-0.50.4-0.6-0.30.3-0.3-0.3
Sr content in liver0.20.10.30.2-0.5-0.3-0.30.4-0.4-0.4
Zn content in liver0.80.91.4-1.20.7-0.9-0.90.9-1.0-1.0
Bone: minimum diameter0.20.31.3-0.71.1-0.0-0.20.1-0.2-0.3
Time in familiar zone, hab. session 11.01.02.0-1.11.4-1.0-0.80.8-0.8-0.8
Time in novel zone, hab. session 10.40.40.7-0.30.3-0.8-0.80.8-0.7-0.7
Total zone transitions, hab. session 10.10.10.20.4-0.30.40.4-0.40.30.4
Total locomotion distance, hab. session 10.10.20.30.5-0.30.50.5-0.50.40.4
Locomotion velocity, hab. session 11.01.31.71.0-1.01.31.2-1.21.21.1
Time in familiar zone, hab. session 20.00.00.2-0.30.4-0.10.1-0.10.10.1
Time in novel zone, hab. session 20.40.40.6-0.40.4-0.5-0.80.8-0.7-0.7
Total zone transitions, hab. session 20.10.10.30.10.20.50.3-0.30.30.3
Total locomotion distance, hab. session 20.10.20.50.10.10.70.5-0.50.40.4
Locomotion velocity, hab. session 20.30.40.90.3-0.10.90.7-0.70.70.6
Novel to familiar place preference ratio0.91.01.3-1.01.1-0.8-1.11.0-1.1-1.1
Novelty place preference1.51.61.9-1.21.4-1.1-1.31.3-1.3-1.3
Time in novel zone, NPP test1.71.92.1-1.21.4-1.2-1.41.4-1.4-1.4
Total zone transitions, NPP test1.52.22.41.5-1.51.51.5-1.41.41.5
Total locomotion distance, NPP test2.02.73.21.6-1.51.81.7-1.61.61.6
Locomotion velocity, NPP test3.14.35.41.9-1.82.32.2-2.12.12.1
Intraocular pressure6.39.111.5-3.33.4-2.6-3.02.9-2.9-2.9
Delta distance traveled before/after self-admin2.12.23.0-1.71.7-1.6-1.31.4-1.3-1.3
Delta ambulatory time before/after self-admin0.40.51.5-1.01.2-0.6-0.40.5-0.4-0.4
Parametrial fat weight12.329.034.3-5.95.5-5.2-5.25.3-5.3-5.3
Pavlov. Cond. lever latency1.51.93.0-0.90.7-1.7-1.51.5-1.5-1.4
Pavlov. Cond. magazine entry latency0.10.10.2-0.20.40.40.3-0.30.30.3
Pavlov. Cond. change in total contacts0.00.00.1-0.10.20.30.2-0.20.20.2
Pavlov. Cond. index score0.60.71.30.20.11.21.0-1.00.90.9
Pavlov. Cond. latency score0.60.71.30.10.21.11.0-1.00.90.9
Pavlov. Cond. lever contacts1.01.22.10.7-0.51.41.2-1.21.21.1
Pavlov. Cond. magazine entry number0.30.40.7-0.2-0.2-0.8-0.80.7-0.8-0.7
Pavlov. Cond. intertrial magazine entries1.51.83.21.4-1.81.41.2-1.11.21.3
Pavlov. Cond. lever-magazine prob. diff.1.11.42.40.6-0.31.51.3-1.31.31.3
Pavlov. Cond. response bias1.11.42.10.8-0.61.41.3-1.31.31.3
Pavlov. Cond. lever latency1.62.22.6-1.61.5-1.4-1.41.5-1.4-1.4
Pavlov. Cond. magazine entry latency0.30.30.50.6-0.50.50.6-0.70.50.5
Pavlov. Cond. change in total contacts0.61.01.31.0-0.91.11.0-1.11.01.0
Pavlov. Cond. index score1.31.71.91.4-1.31.31.3-1.41.21.2
Pavlov. Cond. latency score1.31.72.01.4-1.41.31.3-1.41.21.2
Pavlov. Cond. lever contacts1.11.51.71.3-1.31.21.2-1.31.21.2
Pavlov. Cond. magazine entry number0.10.20.3-0.30.3-0.3-0.50.6-0.4-0.4
Pavlov. Cond. intertrial magazine entries3.55.25.6-2.22.2-2.3-2.42.3-2.3-2.3
Pavlov. Cond. lever-magazine prob. diff.0.81.11.31.0-1.01.11.1-1.21.01.0
Pavlov. Cond. response bias1.72.42.51.6-1.61.51.5-1.61.51.5
Time in closed arm before self-admin0.70.91.5-0.80.8-1.2-1.00.9-1.0-1.0
Time in closed arm after self-admin1.51.62.5-1.11.4-1.6-1.21.1-1.2-1.2
Time in open arm before self-admin0.10.10.60.2-0.00.80.3-0.20.20.3
Time in open arm after self-admin1.31.42.50.8-0.61.61.3-1.21.31.3
Bone: periosteal estimation0.81.72.50.8-0.21.61.5-1.61.51.4
Bone: periosteal perimeter0.40.60.90.3-0.20.90.9-1.00.90.9
Bone: post-yield work1.01.52.21.5-1.50.91.2-1.11.11.2
Progressive ratio test 1 active lever presses1.92.34.01.6-2.01.71.2-1.41.31.3
Progressive ratio test 1 breakpoint1.92.33.91.6-2.01.71.2-1.41.31.3
Progressive ratio test 1 inactive lever presses3.04.46.02.2-2.41.92.0-2.02.02.0
Progressive ratio test 2 active lever presses0.70.82.71.3-1.60.40.5-0.50.40.4
Progressive ratio test 2 breakpoint0.60.62.41.2-1.50.30.4-0.40.30.3
Progressive ratio test 2 inactive lever presses1.32.23.41.7-1.81.11.4-1.51.41.3
Incentive Sensitization - Responses0.20.30.80.8-0.90.10.3-0.30.30.3
Incentive Sensitization - Breakpoint0.10.20.50.7-0.7-0.10.2-0.10.10.2
Sum of active levers in priming session hrs 5-60.60.61.4-0.40.71.20.7-0.70.70.7
Progressive ratio0.00.10.2-0.10.4-0.4-0.10.1-0.1-0.1
Food seeking constrained by brief footshock4.35.38.02.8-2.82.12.1-2.12.12.1
Seeking ratio, punishment vs. effort0.50.81.60.9-1.31.10.7-0.70.70.7
Retroperitoneal fat weight24.2103.0126.7-10.811.3-9.7-9.99.7-9.7-9.8
Reaction time number correct0.40.91.01.0-0.71.01.0-1.00.90.9
Reaction time mean minus median0.00.00.10.3-0.3-0.0-0.10.0-0.0-0.0
Reaction time mean minus median AUC0.00.10.1-0.20.1-0.2-0.30.3-0.3-0.3
Reaction time num false alarms0.40.52.4-1.11.60.4-0.0-0.00.00.0
Reaction time num false alarms AUC0.40.62.5-1.11.60.60.0-0.10.10.0
Reaction time trials correct on left0.40.91.01.0-0.71.01.0-1.00.90.9
Reaction time trials on left0.50.91.01.0-0.71.01.0-1.00.90.9
Reaction time mean0.91.41.9-1.00.6-1.1-1.31.3-1.4-1.4
Reaction time mean AUC0.71.11.6-0.90.5-0.9-1.21.2-1.3-1.2
Median of all reaction times1.11.62.1-1.20.7-1.1-1.41.4-1.5-1.5
Reaction time omissions0.10.20.6-0.40.80.60.2-0.30.30.3
Reaction time false alarm rate0.60.93.1-1.51.80.1-0.50.4-0.4-0.4
Reaction time premature initiation rate0.10.10.2-0.20.0-0.4-0.50.4-0.5-0.4
Reaction time premature initiations0.00.00.10.3-0.30.10.1-0.10.10.1
Std. dev. reaction times0.20.40.5-0.40.4-0.6-0.70.6-0.7-0.7
Reaction time trials completed0.50.91.01.0-0.71.01.0-1.00.90.9
Reaction time trials AUC0.61.11.31.2-0.91.11.1-1.11.11.1
Run reversals in cocaine runway, females0.10.10.50.4-0.70.1-0.20.3-0.2-0.2
Run reversals in cocaine runway, males0.20.21.00.7-1.00.20.2-0.10.20.3
Latency to leave start box in cocaine runway0.70.81.41.0-1.20.90.8-0.90.80.8
Latency to leave start box in cocaine runway, F0.30.41.00.4-0.41.00.5-0.60.50.5
Latency to leave start box in cocaine runway, M0.50.51.81.1-1.3-0.20.3-0.20.20.2
Std. dev. time between licks in bursts0.50.62.7-1.21.6-0.2-0.30.3-0.3-0.3
Total sessions with >9 infusions1.11.33.01.6-1.70.60.8-1.00.90.9
Short access day 1 total inactive lever presses6.48.411.12.3-2.13.33.1-3.13.13.0
Short access day 10 total inactive lever presses1.63.85.01.5-1.62.22.0-2.02.12.1
Short access day 1 total infusions3.64.75.92.4-2.21.92.1-2.32.22.1
Short access day 10 total infusions2.53.24.91.9-2.21.81.6-1.61.61.6
Short access total infusions1.31.62.61.6-1.60.91.1-1.21.11.1
Short access day 1 locomotion3.03.85.62.4-2.31.61.8-1.91.81.8
Short access day 10 total locomotion1.32.33.71.7-1.91.41.4-1.41.41.4
Short access total locomotion0.30.41.30.9-1.10.30.4-0.40.40.4
One hour access (0.3 mA shock)1.61.94.01.8-2.01.01.2-1.11.11.1
Compulsive drug intake1.21.53.8-1.62.0-0.5-0.91.1-0.9-0.9
One hour access (shock baseline)2.33.57.62.4-2.81.31.6-1.61.51.5
Social response proportion0.20.30.4-0.2-0.3-0.6-0.60.5-0.6-0.6
Social responses0.00.10.1-0.30.1-0.1-0.30.2-0.3-0.4
Social time0.20.30.6-0.10.0-0.7-0.60.5-0.7-0.8
Soleus weight4.613.515.83.6-3.24.03.8-3.73.73.7
Bone: stiffness0.00.00.0-0.10.10.10.2-0.20.10.1
Tibialis anterior weight3.511.914.23.2-2.53.83.6-3.63.63.6
Time to tail flick, vehicle, before self-admin0.90.91.3-0.30.4-1.2-1.11.1-1.1-1.1
Time to tail flick, vehicle, after self-admin3.34.35.4-1.81.6-2.3-2.22.1-2.2-2.2
Time to tail flick, test, before self-admin0.00.00.10.20.1-0.00.2-0.20.30.3
Time to tail flick, test, after self-admin0.30.31.11.0-0.90.40.3-0.30.20.3
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.50.5-0.4-0.30.2-0.2-0.3
Delta time to tail flick, test, before/after SA2.02.02.81.6-1.71.61.3-1.21.21.2
Tibia length2.77.58.0-2.72.6-2.8-2.72.7-2.7-2.8
Ambulatory time before self-admin0.10.10.60.5-0.8-0.10.1-0.00.00.0
Ambulatory time after self-admin1.31.62.8-1.20.8-1.7-1.21.3-1.2-1.2
Bone: tissue strength0.80.81.2-0.60.5-1.1-1.01.0-1.0-0.9
Total heroin consumption2.73.24.71.5-1.12.21.9-1.91.91.9
Bone: trabecular number3.35.47.62.0-1.72.72.5-2.42.42.4
Bone: trabecular spacing2.83.74.8-1.61.3-2.2-2.12.2-2.1-2.0
Bone: trabecular thickness0.70.81.20.5-0.51.11.0-1.11.00.9
Bone: trabecular tissue density0.30.40.50.6-0.70.50.7-0.60.70.7
Water consumed over 24 hours0.40.51.20.00.11.10.8-0.80.80.7
Number of responses in last shaping day0.20.20.50.7-0.5-0.30.4-0.40.40.3