Hub : Genes

Slc26a11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Slc26a11 0.29 0.12 0.0e+00 0.26 0.28 0.28 0.29 1.6e-24 1.2e-26 1.3e-26 7.3e-27
2 NAcc gene expression Slc26a11 0.28 0.11 0.0e+00 0.31 0.32 0.32 0.3 4.1e-36 1.0e-37 3.9e-37 2.5e-35
3 pVTA gene expression Slc26a11 0.23 0.11 9.4e-10 0.21 0.22 0.19 0.22 1.7e-09 5.3e-10 7.9e-09 5.6e-10
4 pVTA intron excision ratio chr10_104619289_104620477 0.08 0.06 4.4e-03 0.02 0.05 0.03 0.04 3.9e-02 3.8e-03 2.3e-02 5.9e-03
5 pVTA alternative TSS XM_039087531.1 0.08 0.06 7.4e-03 0.01 0.03 0.01 0 1.7e-01 2.7e-02 7.0e-02 2.0e-01
6 pVTA isoform ratio XM_039087531.1 0.08 0.06 3.4e-03 0 0.03 0 0 2.5e-01 2.3e-02 2.6e-01 2.3e-01
7 Liver intron excision ratio chr10_104614921_104615892 0.04 0.02 1.1e-03 0.01 0.01 0.01 0.01 3.3e-02 1.0e-02 4.2e-02 2.9e-02
8 Liver intron excision ratio chr10_104616084_104616950 0.04 0.03 4.2e-04 0.01 0.02 0.01 0.01 1.6e-02 4.6e-03 2.5e-02 1.7e-02
9 PL gene expression Slc26a11 0.43 0.12 0.0e+00 0.47 0.46 0.5 0.48 1.5e-57 9.1e-57 6.9e-63 2.1e-59
10 OFC gene expression Slc26a11 0.45 0.15 6.6e-09 0.36 0.27 0.31 0.31 2.3e-09 3.2e-07 4.5e-08 3.7e-08
11 Brain intron excision ratio chr10_104613620_104614695 0.03 0.02 5.4e-03 0.03 0.02 0.03 0.03 8.7e-04 4.0e-03 1.9e-03 2.1e-03
12 Brain intron excision ratio chr10_104613624_104614695 0.03 0.02 4.1e-03 0.03 0.02 0.03 0.03 5.4e-04 2.6e-03 1.2e-03 1.3e-03
13 NAcc intron excision ratio chr10_104616084_104616950 0.1 0.07 1.6e-03 0 0.01 0 0.01 1.5e-01 6.5e-03 1.1e-01 5.8e-03
14 Adipose mRNA stability Slc26a11 0.16 0.08 5.6e-17 0.14 0.14 0.14 0.14 1.5e-15 9.1e-16 1.1e-15 1.3e-15
15 BLA gene expression Slc26a11 0.54 0.12 0.0e+00 0.44 0.39 0.41 0.44 7.9e-26 3.9e-22 1.3e-23 1.5e-25
16 Liver gene expression Slc26a11 0.34 0.11 0.0e+00 0.3 0.31 0.32 0.31 6.1e-34 3.4e-35 1.1e-35 2.0e-35
17 Brain alternative TSS XM_039087531.1 0.04 0.03 3.9e-03 0.01 0.02 0.01 0.01 5.0e-02 6.7e-03 1.3e-02 1.3e-02
18 IL gene expression Slc26a11 0.69 0.17 3.8e-10 0.28 0.29 0.27 0.27 2.5e-07 9.5e-08 2.9e-07 3.1e-07
19 Brain isoform ratio NM_001398807.1 0.03 0.02 7.0e-03 0.02 0.01 0.01 0.01 6.8e-03 1.9e-02 2.1e-02 1.9e-02
20 Brain isoform ratio XM_039087531.1 0.03 0.02 5.3e-03 0.02 0.02 0.01 0.01 3.3e-03 3.5e-03 2.0e-02 1.3e-02
21 Adipose isoform ratio XM_039087533.1 0.06 0.04 7.8e-06 0.01 0.04 0.04 0.03 1.9e-02 1.1e-05 1.8e-05 1.0e-04
22 Adipose alternative TSS XM_039087533.1 0.09 0.05 1.8e-08 0.06 0.07 0.05 0.06 2.3e-07 3.3e-08 1.5e-06 3.0e-07
23 Adipose gene expression Slc26a11 0.07 0.04 9.0e-07 0.02 0.04 0.04 0.04 5.9e-03 1.3e-05 3.7e-05 5.6e-05
24 Liver mRNA stability Slc26a11 0.21 0.09 0.0e+00 0.14 0.14 0.13 0.13 5.3e-15 1.5e-15 1.6e-14 1.9e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.20.41.2-0.1-0.2-0.21.1-1.1-1.00.9-0.90.30.40.7-0.7-0.40.50.4-0.1-0.7-0.4-0.80.8-0.4-0.40.40.1
Area under the delay curve1.81.94.91.21.21.2-2.22.22.0-1.81.8-0.9-1.3-1.91.90.9-1.2-0.71.20.90.61.8-1.80.60.7-0.3-0.2
BMI with tail0.93.15.4-1.3-1.7-1.71.7-1.6-1.81.9-1.92.02.10.6-0.6-2.22.12.3-1.8-1.7-2.2-0.40.4-1.9-2.01.72.1
BMI without tail6.012.318.0-3.3-3.8-3.93.6-3.3-3.63.9-3.94.14.11.5-1.5-4.24.24.2-3.9-3.0-4.2-1.41.4-3.6-3.83.03.8
Body weight1.77.223.7-4.9-4.8-4.81.2-0.7-1.11.6-1.64.12.8-1.91.9-3.52.83.5-2.4-0.1-2.81.6-1.6-1.4-1.80.32.5
Weight adjusted by age1.01.14.4-1.9-2.1-2.10.7-0.5-0.60.7-0.71.51.5-0.50.5-1.31.11.3-0.60.2-0.90.7-0.7-0.3-0.4-0.20.7
Bone surface0.10.20.5-0.3-0.2-0.2-0.50.60.6-0.60.5-0.2-0.3-0.50.50.3-0.3-0.40.20.70.5-0.10.10.60.5-0.7-0.4
Bone volume0.10.10.8-0.4-0.4-0.40.4-0.4-0.40.3-0.30.30.20.4-0.4-0.20.30.2-0.2-0.1-0.0-0.90.9-0.1-0.1-0.00.0
Breakpoint value in progressive ratio session1.01.11.7-1.0-1.0-1.11.3-1.2-1.31.3-1.31.11.10.8-0.8-1.01.21.1-0.9-0.9-1.0-0.80.8-1.0-1.00.80.9
Number of licking bursts0.10.10.3-0.5-0.5-0.50.00.1-0.00.1-0.10.40.2-0.30.3-0.40.30.4-0.30.0-0.40.3-0.3-0.2-0.20.10.4
Context. condit. distance diff. score2.22.66.0-0.7-1.1-1.21.0-0.8-1.01.4-1.41.72.21.1-1.1-1.92.01.9-2.5-1.7-1.9-0.50.5-2.1-2.22.02.3
Locomotion velocity, session 15.05.47.72.22.42.4-2.82.72.7-2.82.7-2.7-2.5-1.51.52.7-2.6-2.62.12.02.41.7-1.72.22.2-1.7-2.1
Locomotion distance, session 10.40.62.91.71.51.40.3-0.5-0.40.3-0.3-0.9-0.40.9-0.90.4-0.2-0.40.2-0.9-0.0-0.60.6-0.4-0.30.9-0.0
Locomotion velocity, session 22.83.27.92.72.82.8-1.10.81.0-1.41.4-2.6-2.60.3-0.32.3-2.2-2.32.30.72.0-0.30.31.41.6-0.8-2.0
Locomotion distance, session 20.70.93.00.70.50.51.5-1.7-1.61.3-1.2-0.10.11.6-1.6-0.30.40.30.1-1.2-0.6-0.90.9-0.7-0.50.90.0
Locomotion velocity, session 31.41.62.71.51.61.6-1.51.41.5-1.51.5-1.6-1.1-0.40.41.7-1.5-1.60.91.01.50.6-0.61.11.2-0.8-1.1
Locomotion distance, session 31.11.24.82.22.12.1-0.80.60.8-0.80.8-1.7-1.10.2-0.21.4-1.1-1.40.90.00.90.1-0.10.40.60.1-0.8
Stereotopy head waving bouts, day 30.40.51.10.60.60.7-1.11.01.0-1.01.0-0.7-0.8-0.00.00.7-0.8-0.70.50.60.90.1-0.10.60.6-0.5-0.5
Stereotopy head waving duration, day 30.10.20.70.40.30.3-0.80.80.8-0.70.6-0.2-0.10.0-0.00.3-0.3-0.3-0.30.20.5-0.40.40.10.1-0.10.1
Locomotion velocity, session 70.20.31.21.11.00.9-0.70.70.7-0.50.5-0.6-0.2-0.20.20.4-0.3-0.4-0.3-0.20.3-0.30.3-0.2-0.10.40.2
Locomotion distance, session 71.51.94.92.01.61.40.7-0.8-0.80.8-0.9-0.40.22.0-2.0-0.20.60.2-1.1-2.0-0.5-2.22.2-1.6-1.42.11.0
Stereotopy head waving bouts, day 70.40.41.1-0.7-0.8-0.8-0.30.50.3-0.0-0.00.81.0-0.40.4-0.80.70.8-1.0-0.1-0.70.2-0.2-0.6-0.70.41.0
Stereotopy head waving duration, day 70.50.61.7-1.0-1.0-1.0-0.91.10.9-0.60.60.60.9-1.31.3-0.40.20.4-0.70.7-0.21.1-1.10.20.0-0.40.5
Locomotion velocity, session 80.50.72.70.40.10.0-0.60.70.5-0.10.00.60.5-0.50.5-0.80.70.8-1.4-0.8-1.00.3-0.3-1.2-1.31.41.6
Locomotion distance, session 83.95.78.4-0.5-0.9-1.12.6-2.5-2.62.7-2.71.92.52.5-2.5-2.42.62.4-2.7-2.9-2.6-1.61.6-2.9-2.82.92.6
Degree of sensitization distance2.52.53.4-0.9-1.1-1.21.8-1.7-1.81.8-1.81.61.51.5-1.5-1.61.71.7-1.8-1.6-1.5-1.71.7-1.7-1.71.51.5
Degree of sensitization stereotypy0.70.71.8-1.0-1.1-1.20.2-0.1-0.20.5-0.51.11.4-0.40.4-1.21.01.2-1.2-0.4-1.10.1-0.1-0.9-1.00.61.2
Conditioned locomotion3.64.27.5-2.5-2.7-2.72.1-1.9-2.12.2-2.22.72.60.8-0.8-2.62.42.5-2.2-1.3-2.3-0.60.6-1.7-1.91.21.9
Cocaine response after cond. corrected0.00.10.10.30.30.3-0.30.40.4-0.30.3-0.3-0.10.2-0.20.3-0.1-0.3-0.00.00.2-0.00.00.00.00.10.0
Cocaine response after cond. not corrected0.50.51.01.01.01.0-0.90.90.9-0.90.8-1.0-0.60.0-0.01.0-0.7-1.00.30.40.8-0.10.10.40.4-0.2-0.4
Cocaine response before conditioning0.50.61.31.11.11.1-0.90.90.9-0.90.9-1.1-0.7-0.20.20.9-0.8-1.00.50.40.9-0.30.30.50.5-0.3-0.6
Saline control response0.70.94.4-2.1-1.9-1.90.3-0.1-0.20.4-0.41.41.2-0.30.3-1.10.91.1-0.90.3-0.60.3-0.3-0.2-0.4-0.40.6
Bone: connectivity density0.10.20.60.40.20.20.5-0.6-0.50.5-0.5-0.00.20.6-0.6-0.20.20.2-0.1-0.6-0.3-0.80.8-0.4-0.30.50.2
Bone: cortical apparent density0.91.24.42.12.02.00.1-0.4-0.2-0.20.2-1.6-0.91.3-1.31.2-1.1-1.20.8-0.31.0-0.80.80.40.60.1-1.1
Bone: cortical area1.82.711.3-3.4-3.1-3.00.3-0.0-0.20.4-0.42.11.7-2.22.2-1.41.01.4-1.01.0-1.12.1-2.10.2-0.0-1.00.6
Bone: cortical porosity1.21.43.3-0.7-0.3-0.2-1.21.31.3-1.31.3-0.5-1.1-0.90.91.1-1.1-1.01.21.71.40.9-0.91.51.4-1.8-1.3
Bone: cortical porosity0.70.81.9-0.9-0.6-0.5-1.11.21.1-1.11.0-0.1-0.6-0.90.90.5-0.6-0.50.61.40.90.8-0.81.10.9-1.4-0.7
Bone: cortical thickness1.52.510.1-3.2-2.8-2.70.8-0.6-0.70.6-0.61.71.4-2.02.0-1.10.71.1-0.21.1-1.02.5-2.50.60.4-1.3-0.1
Bone: cortical thickness0.80.92.5-1.6-1.5-1.40.4-0.3-0.40.4-0.41.10.7-1.61.6-0.90.60.9-0.20.3-1.01.5-1.50.0-0.1-0.30.4
Bone: cortical tissue density1.01.45.12.32.22.20.1-0.4-0.1-0.20.2-1.7-1.01.4-1.41.3-1.1-1.30.9-0.31.0-0.90.90.40.70.1-1.2
Condit. Reinf. active minus inactive responses1.31.53.2-1.8-1.8-1.71.4-1.3-1.41.4-1.41.61.50.2-0.2-1.41.31.4-0.9-0.6-1.3-0.10.1-0.8-0.80.40.9
Condit. Reinf. active-inactive response ratio1.11.21.9-1.2-1.3-1.31.3-1.2-1.31.3-1.31.41.20.3-0.3-1.31.31.4-0.8-0.9-1.3-0.30.3-1.0-1.00.81.0
Condit. Reinf. active responses1.82.25.9-2.4-2.4-2.31.9-1.7-1.81.7-1.72.01.90.2-0.2-1.71.61.7-1.1-0.6-1.5-0.10.1-0.8-0.90.30.9
Condit. Reinf. inactive responses0.40.51.3-1.1-1.0-1.01.0-0.9-0.90.8-0.80.80.90.3-0.3-0.70.60.6-0.5-0.2-0.5-0.20.2-0.2-0.3-0.00.2
Incentive salience index mean0.91.12.9-1.7-1.7-1.61.2-1.1-1.21.1-1.11.41.3-0.20.2-1.21.11.2-0.7-0.3-1.10.1-0.1-0.5-0.60.20.6
Condit. Reinf. lever presses0.20.20.5-0.3-0.4-0.40.7-0.7-0.70.7-0.60.40.7-0.10.1-0.50.50.5-0.4-0.4-0.5-0.40.4-0.4-0.40.40.3
Condit. Reinf. active minus inactive responses0.91.13.6-1.3-1.3-1.3-0.20.40.20.1-0.11.11.2-1.61.6-1.10.71.0-0.60.2-1.11.9-1.9-0.3-0.40.10.9
Condit. Reinf. active-inactive response ratio0.90.93.0-1.7-1.6-1.6-0.00.20.00.1-0.01.00.8-1.41.4-0.80.40.8-0.10.7-0.61.6-1.60.20.1-0.60.3
Condit. Reinf. active responses0.71.02.5-0.7-0.9-0.90.7-0.6-0.70.9-0.91.11.4-0.60.6-1.31.11.3-1.0-0.8-1.60.8-0.8-1.0-1.11.01.3
Condit. Reinf. inactive responses0.50.71.70.70.50.50.8-0.9-0.90.9-0.90.20.70.8-0.8-0.50.60.5-0.7-1.3-0.9-0.90.9-1.0-0.91.30.8
Condit. Reinf. lever presses2.02.74.3-0.7-1.0-1.01.9-1.9-1.92.0-2.01.61.80.8-0.8-1.81.91.8-1.7-1.9-2.1-1.01.0-2.0-1.91.91.8
Condit. Reinf. lever reinforcers received1.41.94.5-0.7-1.0-1.01.2-1.1-1.31.5-1.41.51.9-0.10.1-1.81.61.8-1.5-1.5-2.10.3-0.3-1.7-1.71.71.8
Conditioned reinforcement - actives0.40.41.0-0.5-0.6-0.61.0-0.9-0.90.8-0.80.30.80.8-0.8-0.30.60.2-0.6-0.4-0.4-0.80.8-0.4-0.40.20.2
Conditioned reinforcement - inactives0.50.62.2-1.5-1.5-1.50.5-0.4-0.50.5-0.51.10.8-0.00.0-1.00.70.8-1.20.1-0.5-0.00.0-0.2-0.4-0.20.5
Conditioned locomotion0.40.51.2-0.9-0.9-0.91.1-1.1-1.00.8-0.80.40.70.9-0.9-0.20.50.2-0.6-0.1-0.1-0.70.7-0.0-0.1-0.2-0.2
Patch foraging indifference point 0 sec1.21.94.8-0.8-0.9-0.92.1-2.2-2.11.9-1.81.11.01.6-1.6-1.21.21.1-0.7-1.3-1.0-1.51.5-1.0-1.00.90.6
Patch foraging indifference point AUC0.20.20.6-0.3-0.3-0.30.5-0.5-0.50.5-0.50.40.20.7-0.7-0.30.40.4-0.0-0.5-0.2-0.80.8-0.4-0.40.40.3
Delay disc. indifference point, 0s delay0.70.72.2-0.2-0.1-0.1-1.31.51.3-1.01.00.0-0.1-1.51.50.1-0.2-0.2-0.10.70.11.4-1.40.30.2-0.30.3
Delay disc. indifference point, 16s delay0.30.31.40.90.70.7-0.0-0.1-0.10.2-0.20.1-0.10.1-0.1-0.40.20.5-0.1-0.9-0.6-0.20.2-0.8-0.81.20.8
Delay disc. indifference point, 2s delay1.21.33.90.30.30.3-1.61.71.5-1.31.3-0.3-0.8-1.91.90.4-0.8-0.20.91.00.32.0-2.00.70.6-0.6-0.1
Delay disc. indifference point, 24s delay2.82.75.72.32.32.4-1.71.41.5-1.71.7-2.0-2.3-0.50.51.8-2.0-1.72.30.91.70.4-0.41.31.4-0.8-1.5
Delay disc. indifference point, 4s delay1.21.34.00.20.20.2-1.91.91.7-1.41.3-0.1-0.6-2.02.00.3-0.5-0.10.60.7-0.02.0-2.00.30.2-0.20.4
Delay disc. indifference point, 8s delay4.14.29.81.21.21.3-3.13.13.0-2.72.6-1.4-1.7-2.72.71.5-1.8-1.41.71.81.32.6-2.61.51.4-1.2-0.8
Indifference point function ln k0.30.41.71.31.21.10.3-0.5-0.40.2-0.2-0.8-0.30.7-0.70.4-0.2-0.4-0.0-0.70.1-0.90.9-0.3-0.10.6-0.2
Indifference point function log k0.30.41.71.31.21.10.3-0.5-0.40.2-0.2-0.8-0.30.7-0.70.4-0.2-0.4-0.0-0.70.1-0.90.9-0.3-0.10.6-0.2
Patch foraging total patch changes 0 sec1.82.86.7-0.9-1.0-1.02.5-2.6-2.52.3-2.21.41.41.9-1.9-1.51.51.4-1.1-1.7-1.4-1.71.7-1.5-1.41.30.9
Patch foraging total patch changes 12 sec1.11.44.3-0.7-0.7-0.61.9-2.1-2.01.6-1.50.90.41.7-1.7-0.70.70.80.1-1.0-0.5-1.61.6-0.6-0.60.50.0
Patch foraging total patch changes 18 sec2.22.84.5-0.4-0.6-0.62.0-2.1-2.12.0-2.01.41.31.8-1.8-1.61.61.6-1.1-2.1-1.7-1.61.6-1.9-1.92.01.6
Patch foraging total patch changes 24 sec1.21.52.8-1.5-1.7-1.71.3-1.2-1.31.4-1.41.71.30.3-0.3-1.51.51.6-1.0-0.9-1.4-0.20.2-1.1-1.20.81.2
Patch foraging total patch changes 6 sec0.71.03.5-1.2-1.0-0.91.7-1.9-1.81.3-1.30.70.41.2-1.2-0.30.50.30.4-0.3-0.1-1.21.2-0.0-0.0-0.3-0.5
Patch foraging time to switch 0 sec0.91.32.21.11.31.3-1.41.31.3-1.31.3-1.3-1.5-0.50.51.2-1.3-1.31.40.91.10.9-0.91.01.0-0.7-1.0
Patch foraging water rate 0 sec4.06.410.2-2.7-3.0-3.02.6-2.3-2.52.7-2.73.23.00.8-0.8-3.23.03.2-3.0-1.9-2.9-0.70.7-2.4-2.51.92.6
Patch foraging water rate 12 sec2.53.95.5-0.5-0.9-1.02.3-2.2-2.22.3-2.31.52.11.8-1.8-2.12.22.0-2.3-2.3-2.1-1.71.7-2.2-2.22.22.0
Patch foraging water rate 18 sec3.34.57.1-1.4-1.8-1.92.3-2.1-2.22.4-2.42.02.51.7-1.7-2.12.52.1-2.7-2.0-2.1-1.91.9-2.2-2.31.92.1
Patch foraging water rate 24 sec9.413.117.1-2.5-2.9-3.13.9-3.8-3.94.1-4.13.84.12.7-2.7-4.14.14.1-4.1-3.6-3.9-2.82.8-3.9-4.03.53.7
Patch foraging water rate 6 sec0.91.32.2-0.5-0.8-0.91.2-1.1-1.11.3-1.31.01.30.5-0.5-1.11.41.2-1.5-1.3-1.5-0.40.4-1.4-1.41.31.4
Seeking ratio, delayed vs. immediate footshock0.40.51.7-0.9-0.9-0.9-0.00.10.1-0.10.10.30.5-1.11.1-0.30.00.20.60.7-0.21.3-1.30.50.4-0.8-0.2
Distance traveled before self-admin0.60.72.3-1.0-1.0-1.0-0.60.80.6-0.40.40.70.5-1.51.5-0.70.30.6-0.40.6-0.51.5-1.50.1-0.0-0.30.5
Distance traveled after self-admin2.12.33.7-0.7-0.9-1.01.9-1.8-1.81.9-1.91.21.71.4-1.4-1.31.71.3-1.9-1.6-1.6-1.41.4-1.6-1.61.51.4
Extensor digitorum longus weight1.35.28.3-0.3-0.8-0.92.8-2.9-2.92.8-2.81.82.12.2-2.2-2.22.32.2-2.1-2.8-2.3-2.42.4-2.5-2.42.62.0
Bone: elastic displacement0.91.02.4-1.5-1.4-1.41.6-1.6-1.51.3-1.31.11.30.4-0.4-0.90.90.9-0.5-0.3-0.9-0.10.1-0.3-0.3-0.00.1
Bone: elastic work1.41.89.8-3.1-2.8-2.71.1-1.0-1.00.9-0.81.71.5-0.90.9-1.00.81.0-0.30.9-0.61.1-1.10.50.3-1.2-0.2
Bone: endosteal estimation0.30.61.8-0.0-0.2-0.30.2-0.2-0.30.4-0.50.60.50.8-0.8-0.70.80.7-1.0-0.9-0.6-1.41.4-1.0-1.01.01.1
Bone: endosteal perimeter0.30.61.6-1.1-0.9-0.9-1.11.31.1-0.90.80.4-0.3-1.21.2-0.0-0.1-0.0-0.21.10.30.8-0.80.60.4-0.90.0
Epididymis fat weight1.22.85.1-2.0-2.2-2.31.4-1.2-1.41.6-1.62.21.90.1-0.1-2.22.02.3-2.0-1.1-2.0-0.20.2-1.5-1.71.11.9
Delta time in closed arm before/after self-admin0.50.51.4-0.2-0.2-0.2-0.80.80.8-0.70.7-0.3-0.4-1.11.10.4-0.5-0.40.80.90.41.2-1.20.70.6-0.8-0.4
Delta time in open arm before/after self-admin1.11.11.8-0.7-0.7-0.81.3-1.3-1.31.3-1.31.01.00.7-0.7-1.01.11.0-0.9-1.2-1.2-0.60.6-1.2-1.11.11.0
Diff in mean of infusions in LGA sessions0.00.00.1-0.1-0.1-0.10.1-0.1-0.20.2-0.20.2-0.00.1-0.1-0.20.10.30.1-0.2-0.20.1-0.1-0.2-0.20.20.2
Delay discount exponential model param2.42.56.1-1.4-1.4-1.52.5-2.4-2.32.0-2.01.11.62.0-2.0-1.11.50.9-1.6-1.0-0.8-1.91.9-0.8-0.90.50.4
Extinction: sum of active levers before priming0.30.31.21.11.11.00.1-0.2-0.10.0-0.0-0.8-0.40.7-0.70.7-0.2-0.60.1-0.50.2-0.60.6-0.2-0.10.5-0.1
Active lever presses in extinction session 60.30.30.9-0.6-0.7-0.70.5-0.5-0.60.6-0.60.80.5-0.10.1-0.90.70.9-0.3-0.5-0.8-0.00.0-0.6-0.60.50.7
Bone: final force1.62.611.1-3.3-3.1-3.00.6-0.2-0.50.7-0.72.41.8-1.41.4-1.81.41.8-1.20.5-1.41.6-1.6-0.3-0.6-0.41.1
Bone: final moment1.82.912.8-3.6-3.4-3.30.8-0.4-0.70.9-0.92.52.0-1.11.1-1.91.51.9-1.30.4-1.51.4-1.4-0.3-0.6-0.51.1
Food consumed during 24 hour testing period1.31.54.1-1.2-1.4-1.40.8-0.6-0.81.0-1.01.61.90.3-0.3-1.51.51.5-2.0-0.9-1.4-0.40.4-1.3-1.41.01.6
Glucose2.53.87.62.52.72.7-1.41.11.3-1.71.7-2.8-2.10.5-0.52.6-2.5-2.62.21.22.6-0.20.21.92.1-1.4-2.5
Heart weight0.30.50.9-0.9-0.9-0.90.9-0.9-0.90.8-0.80.80.70.6-0.6-0.60.70.6-0.7-0.4-0.4-0.70.7-0.4-0.40.20.3
Delay discount hyperbolic model param2.22.45.8-1.3-1.3-1.32.4-2.3-2.22.0-1.91.01.52.0-2.0-1.01.40.8-1.4-1.0-0.7-2.02.0-0.8-0.80.40.3
Intermittent access intake day 1-15 change0.10.10.6-0.3-0.3-0.3-0.40.50.4-0.30.20.30.2-0.80.8-0.30.10.5-0.50.2-0.20.4-0.4-0.1-0.1-0.00.4
Intermittent access intake escalation0.20.10.4-0.5-0.5-0.5-0.10.20.1-0.0-0.00.50.3-0.50.5-0.50.40.5-0.60.0-0.40.2-0.2-0.2-0.30.10.5
Intermittent access intake escalation 20.20.20.5-0.6-0.7-0.7-0.40.50.4-0.30.30.30.0-0.70.7-0.20.00.2-0.00.60.10.5-0.50.30.2-0.5-0.0
Intermitt. access day 1 inactive lever presses0.70.82.8-1.7-1.6-1.60.3-0.1-0.30.4-0.41.31.0-0.70.7-1.00.81.0-1.40.1-0.80.5-0.5-0.3-0.5-0.10.7
Intermitt. access day 15 inactive lever presses1.61.73.1-1.6-1.6-1.61.3-1.2-1.31.4-1.41.61.80.2-0.2-1.51.61.5-1.6-0.9-1.6-0.30.3-1.2-1.30.91.4
Intermitt. access escalation Index0.80.72.1-1.4-1.4-1.40.7-0.5-0.60.7-0.71.21.1-0.10.1-1.21.01.1-0.7-0.2-0.90.1-0.1-0.5-0.60.20.7
Intermittent access day 1 total infusions0.30.30.8-0.6-0.5-0.60.9-0.9-0.80.7-0.70.30.60.8-0.8-0.30.40.1-0.4-0.3-0.2-0.80.8-0.2-0.20.0-0.0
Intermittent access day 15 total infusions0.30.30.9-0.9-1.0-1.00.6-0.5-0.60.6-0.60.70.70.2-0.2-0.70.60.6-0.6-0.2-0.5-0.40.4-0.3-0.40.10.4
Intermittent access terminal intake (last 3 days)0.20.31.1-1.1-1.1-1.10.5-0.4-0.40.4-0.40.60.70.1-0.1-0.50.50.4-0.40.1-0.3-0.20.2-0.0-0.1-0.30.1
Intermittent access total infusions0.40.40.8-0.9-0.9-0.90.8-0.8-0.80.7-0.70.60.80.6-0.6-0.60.60.4-0.6-0.2-0.4-0.70.7-0.3-0.30.00.2
Intermittent access day 1 locomotion0.70.81.7-1.0-1.0-1.01.3-1.3-1.31.1-1.10.80.80.9-0.9-0.80.80.5-0.6-0.5-0.5-0.90.9-0.5-0.50.20.3
Intermittent access day 15 total locomotion0.10.10.5-0.7-0.7-0.70.2-0.1-0.10.1-0.10.20.2-0.00.0-0.10.1-0.10.00.40.10.0-0.00.30.2-0.5-0.2
Intermittent access total locomotion0.50.61.2-1.1-1.1-1.11.0-1.0-1.00.9-0.90.80.70.7-0.7-0.60.70.5-0.7-0.3-0.4-0.70.7-0.4-0.40.10.3
Intermittent access standard deviation1.11.23.50.50.50.5-1.81.91.7-1.51.5-0.7-0.7-1.61.60.7-0.8-0.60.41.00.51.4-1.40.70.6-0.6-0.1
Left kidney weight1.23.38.7-0.8-0.5-0.4-2.42.62.4-2.12.1-0.3-1.0-3.03.00.7-1.1-0.70.92.21.02.7-2.71.61.4-1.9-0.7
Right kidney weight0.61.75.9-0.9-0.7-0.6-1.61.71.5-1.41.30.2-0.5-2.42.40.1-0.6-0.10.61.50.32.2-2.21.00.8-1.2-0.3
Cocaine induced anxiety1.51.76.8-2.5-2.6-2.50.10.1-0.10.3-0.42.01.3-1.21.2-1.51.11.7-1.00.5-1.01.2-1.2-0.2-0.4-0.40.9
Post-drug Anxiety0.91.03.0-1.3-1.5-1.40.3-0.2-0.40.6-0.61.70.6-0.40.4-1.71.11.7-0.7-0.5-1.30.4-0.4-1.0-1.10.71.4
Baseline Anxiety1.81.97.62.82.82.7-1.00.80.9-0.90.9-2.0-1.90.5-0.51.5-1.3-1.61.4-0.41.0-0.60.60.10.40.6-0.6
Tail length2.47.124.3-4.9-4.8-4.81.9-1.5-1.82.1-2.14.02.8-1.01.0-3.23.03.2-2.6-0.5-2.70.7-0.7-1.5-1.90.42.4
Length with tail1.14.016.0-4.0-3.5-3.5-0.81.30.9-0.60.52.30.6-3.13.1-1.40.81.3-0.61.9-0.72.7-2.70.70.3-1.70.6
Length without tail2.65.810.3-0.20.30.4-3.03.13.0-2.92.9-1.1-2.1-3.23.21.5-2.2-1.62.23.02.02.9-2.92.62.4-2.7-1.8
Times rat made contact with spout0.40.41.7-1.3-1.2-1.10.9-0.8-0.80.6-0.60.71.00.4-0.4-0.40.40.4-0.50.2-0.2-0.00.00.10.1-0.5-0.2
Lifetime Intake0.10.10.2-0.4-0.4-0.40.4-0.3-0.30.3-0.30.10.40.4-0.4-0.10.20.0-0.4-0.0-0.0-0.40.4-0.0-0.0-0.1-0.0
Liver weight, left1.11.84.30.30.50.5-2.02.12.0-1.91.8-1.0-0.7-1.41.41.2-1.3-1.20.91.61.31.3-1.31.31.2-1.3-0.9
Liver weight, right1.32.16.6-2.4-1.9-1.8-0.70.90.7-0.60.71.00.2-2.62.6-0.4-0.20.50.61.7-0.02.5-2.51.21.0-1.7-0.4
Locomotor activity0.10.20.70.80.90.8-0.40.30.3-0.30.3-0.6-0.40.2-0.20.5-0.3-0.60.1-0.20.2-0.30.3-0.1-0.00.3-0.0
Locomotor testing distance0.10.10.50.60.50.5-0.10.10.10.0-0.1-0.20.20.3-0.3-0.00.1-0.0-0.4-0.5-0.2-0.40.4-0.5-0.50.70.5
Locomotor testing rearing1.11.72.7-0.4-0.6-0.61.4-1.3-1.41.5-1.51.21.50.9-0.9-1.51.41.5-1.5-1.6-1.6-1.01.0-1.6-1.61.61.5
Locomotion in novel chamber0.30.40.6-0.4-0.4-0.50.7-0.7-0.70.7-0.70.60.40.7-0.7-0.50.70.6-0.4-0.7-0.6-0.70.7-0.7-0.70.70.7
Locomotion in novel chamber post-restriction0.20.31.0-0.8-0.8-0.80.6-0.6-0.60.4-0.40.40.20.5-0.5-0.10.30.1-0.10.20.3-1.01.00.20.1-0.5-0.3
Fecal boli incidents, locomotor time 10.40.41.21.00.90.90.6-0.7-0.50.3-0.3-0.8-0.21.1-1.10.3-0.3-0.20.1-0.40.4-1.11.10.10.20.2-0.6
Change in fecal boli incidents, locomotor task1.81.74.31.92.02.0-0.90.70.8-1.01.0-1.7-2.00.4-0.41.7-1.5-1.72.10.41.5-0.50.50.91.0-0.5-1.3
Time >=10cm from walls, locomotor time 10.70.72.40.1-0.2-0.30.4-0.3-0.40.7-0.70.61.00.1-0.1-0.91.00.8-1.5-1.1-1.2-0.30.3-1.2-1.21.31.3
Bouts of movement, locomotor time 10.91.03.41.91.71.7-0.30.10.2-0.40.4-1.5-1.20.8-0.81.3-1.0-1.30.9-0.11.0-1.01.00.40.6-0.0-0.9
Total resting periods, locomotor time 11.41.54.32.11.91.9-0.30.10.3-0.60.6-1.9-1.51.0-1.01.7-1.3-1.71.20.11.3-1.11.10.70.9-0.3-1.3
Rest time, locomotor task time 10.70.71.70.70.80.8-0.30.20.4-0.60.6-1.2-1.00.6-0.61.3-1.0-1.30.90.71.3-0.40.41.01.0-0.9-1.3
Distance moved, locomotor task time 10.60.71.9-1.2-1.2-1.20.4-0.3-0.40.6-0.61.30.8-0.60.6-1.40.91.3-0.4-0.3-1.00.5-0.5-0.6-0.70.40.9
Vertical activity count, locomotor time 11.41.52.9-1.2-1.2-1.21.1-0.9-1.01.2-1.21.51.70.1-0.1-1.71.51.6-1.6-1.0-1.6-0.10.1-1.3-1.31.11.4
Time >=10cm from walls, locomotor time 20.10.10.2-0.3-0.3-0.20.2-0.3-0.30.2-0.20.2-0.30.4-0.4-0.20.00.10.30.00.2-0.40.40.10.0-0.2-0.2
Bouts of movement, locomotor time 20.40.52.01.41.31.3-0.60.40.5-0.50.5-1.0-0.8-0.00.00.8-0.7-0.90.3-0.00.5-0.10.10.20.30.1-0.4
Total resting periods, locomotor time 20.20.31.31.11.01.0-0.40.30.3-0.30.3-0.8-0.50.0-0.00.6-0.5-0.70.1-0.10.3-0.10.10.10.10.2-0.2
Rest time, locomotor task time 20.20.20.60.50.50.5-0.30.30.3-0.40.4-0.7-0.60.3-0.30.8-0.5-0.70.30.30.6-0.30.30.40.4-0.3-0.5
Distance moved, locomotor task time 20.30.31.0-0.9-0.7-0.7-0.30.30.2-0.20.20.6-0.0-1.01.0-0.50.00.40.50.5-0.21.0-1.00.20.1-0.40.1
Vertical activity count, locomotor time 20.50.51.2-0.8-0.7-0.70.4-0.3-0.40.5-0.61.00.8-0.40.4-1.10.81.0-0.9-0.5-1.10.6-0.6-0.7-0.80.60.9
Light reinforcement 12.24.08.1-1.9-2.0-2.12.6-2.5-2.62.5-2.52.02.91.0-1.0-1.92.21.9-2.2-1.7-2.2-0.80.8-1.7-1.81.41.6
Light reinforcement 20.91.34.1-2.0-1.9-1.90.9-0.7-0.70.9-0.91.51.8-0.40.4-1.21.31.2-1.2-0.1-1.20.8-0.8-0.5-0.70.10.9
Bone: marrow area0.30.61.6-0.0-0.2-0.30.2-0.1-0.20.4-0.50.60.50.7-0.7-0.70.80.7-1.1-0.9-0.6-1.31.3-1.0-1.01.01.1
Bone: maximum diameter0.91.76.1-1.9-1.7-1.7-1.21.51.3-0.90.91.00.4-2.52.5-0.50.20.4-0.51.4-0.21.9-1.90.60.3-1.10.4
Bone: maximum force1.52.611.1-3.3-3.1-3.10.9-0.6-0.80.9-0.92.41.8-1.11.1-1.81.51.8-1.20.4-1.41.2-1.2-0.3-0.6-0.41.0
Bone: maximum moment1.72.912.6-3.5-3.4-3.31.1-0.8-1.01.1-1.12.51.9-0.80.8-1.91.61.9-1.30.3-1.41.0-1.0-0.4-0.6-0.41.0
Mean time between licks in bursts0.40.61.91.41.31.3-0.80.60.7-0.70.7-1.0-1.00.4-0.40.8-0.8-0.90.50.10.8-0.40.40.30.4-0.0-0.5
Mean num. licks in bursts0.30.31.1-0.5-0.4-0.41.0-1.1-1.00.8-0.80.40.60.9-0.9-0.20.30.2-0.2-0.3-0.2-0.50.5-0.1-0.10.0-0.2
Cd content in liver0.60.61.91.10.80.80.7-0.8-0.80.7-0.70.00.40.9-0.9-0.40.40.4-0.5-1.3-0.7-0.60.6-1.0-0.91.40.7
Co content in liver0.70.81.80.1-0.0-0.11.3-1.3-1.31.1-1.10.40.61.4-1.4-0.60.70.6-0.6-1.1-0.6-1.01.0-0.8-0.70.90.4
Cu content in liver0.20.31.0-0.3-0.1-0.0-0.20.20.2-0.40.4-0.3-0.5-0.30.30.6-0.6-0.60.70.80.70.2-0.20.90.8-1.0-0.9
Fe content in liver0.40.52.00.90.70.6-0.0-0.0-0.00.0-0.1-0.3-0.31.4-1.40.10.0-0.1-0.3-0.60.3-1.41.4-0.4-0.40.60.2
K content in liver1.01.02.7-1.6-1.6-1.61.0-0.9-0.91.0-1.01.41.40.1-0.1-1.11.11.1-1.1-0.3-0.9-0.10.1-0.5-0.60.20.7
Mg content in liver1.31.42.8-0.3-0.5-0.61.7-1.7-1.61.5-1.50.81.01.4-1.4-0.91.10.9-1.0-1.3-1.0-1.31.3-1.1-1.01.00.7
Mn content in liver0.50.51.5-0.5-0.3-0.3-1.11.21.1-0.90.90.10.1-1.11.10.3-0.3-0.3-0.30.90.31.2-1.20.50.4-0.6-0.1
Na content in liver0.50.51.0-0.00.20.2-0.80.80.8-0.80.8-0.4-0.2-1.01.00.7-0.6-0.70.40.90.51.0-1.00.80.7-0.8-0.6
Rb content in liver1.92.43.7-1.3-1.4-1.51.9-1.9-1.91.9-1.91.81.60.6-0.6-1.81.71.8-1.3-1.5-1.8-0.90.9-1.5-1.61.31.4
Se content in liver0.40.51.2-0.6-0.7-0.80.4-0.3-0.40.6-0.61.00.90.4-0.4-0.90.90.9-1.1-0.6-0.8-0.40.4-0.8-0.80.70.9
Sr content in liver1.51.42.90.30.70.8-0.80.60.8-1.01.1-1.2-1.5-0.20.21.4-1.5-1.41.71.31.50.8-0.81.51.6-1.5-1.7
Zn content in liver1.41.52.60.10.50.6-1.01.01.1-1.21.2-1.0-1.5-0.90.91.3-1.3-1.31.61.51.41.1-1.11.61.6-1.6-1.5
Bone: minimum diameter1.01.98.3-2.9-2.7-2.70.6-0.3-0.50.7-0.72.11.5-1.11.1-1.61.31.6-1.30.3-1.10.8-0.8-0.3-0.6-0.41.0
Time in familiar zone, hab. session 10.50.52.20.20.10.10.7-0.8-0.80.6-0.60.10.51.2-1.2-0.30.30.2-0.4-0.6-0.1-1.51.5-0.4-0.40.40.1
Time in novel zone, hab. session 10.40.41.2-0.1-0.1-0.2-0.91.10.9-0.70.60.10.1-1.11.1-0.0-0.00.0-0.30.4-0.21.0-1.00.0-0.1-0.00.4
Total zone transitions, hab. session 10.60.92.90.50.30.21.1-1.2-1.11.0-1.00.30.31.7-1.7-0.60.70.6-0.4-1.3-0.7-1.01.0-1.0-0.91.20.6
Total locomotion distance, hab. session 11.82.53.3-0.7-1.0-1.11.7-1.7-1.81.8-1.81.51.81.3-1.3-1.71.71.7-1.7-1.7-1.7-1.11.1-1.8-1.81.71.6
Locomotion velocity, hab. session 11.62.33.5-0.8-1.0-1.01.9-1.9-1.91.9-1.91.41.51.4-1.4-1.61.61.6-1.4-1.6-1.6-1.11.1-1.6-1.61.51.4
Time in familiar zone, hab. session 20.50.51.70.40.20.10.5-0.5-0.50.5-0.60.20.61.3-1.3-0.40.60.4-0.8-0.9-0.4-1.21.2-0.8-0.80.90.7
Time in novel zone, hab. session 20.30.30.50.20.30.3-0.60.60.6-0.60.6-0.4-0.5-0.70.70.4-0.5-0.40.50.50.40.6-0.60.50.5-0.4-0.4
Total zone transitions, hab. session 22.22.86.10.3-0.0-0.12.3-2.5-2.42.2-2.10.81.12.3-2.3-1.21.41.2-1.0-2.1-1.4-1.61.6-1.7-1.61.91.1
Total locomotion distance, hab. session 22.93.98.3-0.9-1.1-1.12.8-2.9-2.82.6-2.61.62.12.0-2.0-1.81.91.8-1.6-2.1-1.9-1.41.4-1.8-1.81.81.3
Locomotion velocity, hab. session 22.63.67.8-1.1-1.3-1.32.8-2.8-2.72.6-2.51.72.01.7-1.7-1.81.91.9-1.4-1.9-1.9-1.11.1-1.7-1.71.61.3
Novel to familiar place preference ratio2.02.05.5-1.6-1.6-1.52.3-2.3-2.32.0-1.91.41.61.5-1.5-1.31.21.4-0.5-0.9-1.2-0.30.3-0.7-0.70.40.3
Novelty place preference1.71.74.5-1.6-1.5-1.42.1-2.1-2.01.8-1.71.31.41.5-1.5-1.21.11.2-0.4-0.7-1.0-0.20.2-0.6-0.60.30.3
Time in novel zone, NPP test1.92.05.2-1.5-1.4-1.42.2-2.3-2.21.9-1.91.41.51.7-1.7-1.31.21.3-0.6-1.0-1.2-0.50.5-0.8-0.80.50.4
Total zone transitions, NPP test1.41.93.70.40.10.01.8-1.9-1.81.7-1.70.61.01.7-1.7-1.11.21.1-1.1-1.9-1.4-1.31.3-1.6-1.51.81.1
Total locomotion distance, NPP test3.75.110.7-0.5-0.8-0.93.2-3.3-3.23.0-3.01.62.12.5-2.5-2.02.12.0-1.7-2.6-2.2-2.12.1-2.3-2.12.31.6
Locomotion velocity, NPP test3.04.39.3-0.6-0.9-1.03.0-3.0-3.02.8-2.71.52.02.2-2.2-1.82.01.9-1.5-2.3-2.0-1.81.8-2.0-1.92.01.4
Intraocular pressure1.21.73.7-0.8-0.9-0.91.8-1.9-1.91.7-1.71.31.01.3-1.3-1.11.21.2-1.0-1.3-1.2-1.31.3-1.1-1.11.00.8
Delta distance traveled before/after self-admin2.32.54.50.0-0.1-0.22.1-2.1-2.01.9-1.90.71.22.1-2.1-0.71.40.9-1.5-2.0-1.3-2.12.1-1.6-1.51.71.1
Delta ambulatory time before/after self-admin1.82.05.30.50.50.31.8-1.9-1.71.6-1.60.20.72.2-2.2-0.20.90.4-1.0-1.8-0.7-2.32.3-1.3-1.21.50.7
Parametrial fat weight0.50.94.3-2.1-1.9-1.90.9-0.8-0.80.8-0.81.50.8-0.10.1-1.10.91.0-0.60.1-0.6-0.10.1-0.2-0.4-0.30.4
Pavlov. Cond. lever latency2.22.87.31.00.40.31.0-1.0-1.11.4-1.40.81.52.0-2.0-1.41.61.4-2.2-2.4-1.7-1.81.8-2.4-2.32.72.2
Pavlov. Cond. magazine entry latency1.01.34.3-1.8-1.5-1.4-0.91.00.9-0.80.80.5-0.3-2.12.10.1-0.3-0.10.51.60.41.4-1.41.10.9-1.6-0.5
Pavlov. Cond. change in total contacts0.20.20.9-0.4-0.2-0.10.5-0.6-0.50.2-0.1-0.2-0.4-0.10.10.4-0.4-0.41.00.50.40.0-0.00.70.7-0.8-1.0
Pavlov. Cond. index score1.21.65.0-2.2-1.8-1.7-0.40.60.5-0.60.60.7-0.1-2.12.1-0.0-0.30.10.81.70.31.7-1.71.31.1-1.8-0.8
Pavlov. Cond. latency score1.62.15.2-1.9-1.4-1.3-0.91.01.0-1.11.10.2-0.6-2.22.20.5-0.8-0.51.32.10.91.9-1.91.81.6-2.3-1.3
Pavlov. Cond. lever contacts0.81.03.2-1.1-0.7-0.5-0.0-0.00.1-0.40.5-0.2-0.7-1.11.10.6-0.8-0.61.41.40.91.0-1.01.51.4-1.8-1.5
Pavlov. Cond. magazine entry number1.21.53.41.51.21.11.1-1.3-1.21.1-1.1-0.10.81.7-1.7-0.40.60.4-0.9-1.8-0.9-1.41.4-1.4-1.21.80.9
Pavlov. Cond. intertrial magazine entries1.21.43.3-0.2-0.4-0.41.8-1.8-1.71.6-1.60.81.11.4-1.4-1.01.10.9-0.9-1.3-1.0-1.21.2-1.1-1.01.10.7
Pavlov. Cond. lever-magazine prob. diff.1.11.45.3-2.3-1.9-1.8-0.20.30.2-0.30.30.90.1-2.02.0-0.3-0.00.30.61.50.11.6-1.61.00.8-1.6-0.5
Pavlov. Cond. response bias1.01.23.4-1.6-1.2-1.1-0.60.70.6-0.70.80.2-0.7-1.51.50.4-0.6-0.41.11.70.81.3-1.31.41.3-1.9-1.1
Pavlov. Cond. lever latency3.14.26.21.21.51.5-2.52.42.5-2.52.5-2.0-2.1-1.71.72.2-2.3-2.22.02.12.21.7-1.72.22.2-2.0-1.9
Pavlov. Cond. magazine entry latency2.32.75.50.80.50.41.5-1.6-1.61.6-1.70.60.92.2-2.2-1.11.31.1-1.3-2.3-1.3-2.32.3-2.1-1.92.31.6
Pavlov. Cond. change in total contacts2.12.95.20.1-0.2-0.32.0-2.1-2.12.1-2.11.11.41.7-1.7-1.51.71.5-1.6-2.3-1.8-1.71.7-2.0-1.92.21.6
Pavlov. Cond. index score3.03.86.1-0.2-0.5-0.62.1-2.2-2.22.2-2.31.51.72.0-2.0-1.82.01.8-1.9-2.5-2.0-2.12.1-2.3-2.32.42.0
Pavlov. Cond. latency score3.03.75.8-0.3-0.6-0.72.1-2.1-2.12.2-2.21.51.71.8-1.8-1.92.01.9-1.9-2.4-2.1-1.91.9-2.3-2.32.42.1
Pavlov. Cond. lever contacts3.44.66.6-1.4-1.7-1.82.5-2.4-2.52.6-2.62.22.41.4-1.4-2.42.52.4-2.2-2.2-2.4-1.51.5-2.3-2.32.12.2
Pavlov. Cond. magazine entry number2.83.56.7-0.6-0.3-0.2-1.92.02.0-2.02.0-0.9-1.4-2.32.31.3-1.7-1.41.72.61.72.3-2.32.32.2-2.6-1.8
Pavlov. Cond. intertrial magazine entries0.70.92.4-1.5-1.5-1.50.10.1-0.00.2-0.21.11.2-1.31.3-0.90.60.9-0.80.4-0.81.3-1.3-0.1-0.2-0.30.6
Pavlov. Cond. lever-magazine prob. diff.3.03.96.40.0-0.4-0.52.2-2.2-2.22.2-2.21.31.72.1-2.1-1.72.01.7-1.9-2.5-1.9-2.22.2-2.4-2.32.51.9
Pavlov. Cond. response bias2.83.85.5-0.6-0.9-1.02.3-2.3-2.32.3-2.31.62.01.7-1.7-1.92.11.9-2.0-2.3-2.1-1.81.8-2.3-2.22.32.0
Time in closed arm before self-admin0.50.51.40.91.01.0-0.80.60.7-0.80.8-0.8-1.20.1-0.10.8-0.9-0.80.80.40.9-0.30.30.60.6-0.4-0.7
Time in closed arm after self-admin2.32.44.81.11.21.3-1.81.71.7-1.81.8-1.5-2.2-0.90.91.6-1.8-1.62.01.51.80.7-0.71.61.6-1.4-1.5
Time in open arm before self-admin0.40.40.90.10.20.2-0.70.80.9-0.70.8-0.4-0.1-0.90.90.3-0.5-0.30.20.80.51.0-1.00.70.7-0.6-0.5
Time in open arm after self-admin0.20.30.4-0.1-0.1-0.20.6-0.6-0.60.6-0.60.30.60.4-0.4-0.40.60.3-0.7-0.6-0.6-0.30.3-0.6-0.60.60.5
Bone: periosteal estimation0.61.34.8-2.2-2.1-2.10.3-0.1-0.30.5-0.51.71.4-0.90.9-1.31.11.3-1.30.1-1.00.4-0.4-0.4-0.6-0.11.0
Bone: periosteal perimeter1.52.56.7-2.3-1.9-1.8-1.31.61.4-1.31.30.6-0.1-2.62.60.1-0.5-0.20.42.20.62.2-2.21.51.3-2.2-0.7
Bone: post-yield work0.40.51.6-0.0-0.1-0.11.2-1.2-1.21.0-1.00.30.51.0-1.0-0.40.50.4-0.4-0.8-0.5-0.70.7-0.5-0.50.60.2
Progressive ratio test 1 active lever presses0.50.51.2-0.9-0.9-0.91.0-0.9-0.90.9-0.90.61.00.4-0.4-0.80.70.6-1.1-0.4-0.6-0.40.4-0.4-0.40.20.3
Progressive ratio test 1 breakpoint0.60.61.5-1.0-1.0-1.01.2-1.1-1.01.0-1.00.61.10.5-0.5-0.80.80.6-1.2-0.4-0.6-0.60.6-0.4-0.50.20.3
Progressive ratio test 1 inactive lever presses1.82.05.0-2.2-2.2-2.21.1-0.9-1.01.2-1.21.91.9-0.40.4-1.81.61.7-1.8-0.5-1.60.4-0.4-0.9-1.10.51.3
Progressive ratio test 2 active lever presses0.20.20.5-0.7-0.7-0.70.6-0.5-0.50.4-0.40.40.50.3-0.3-0.30.40.2-0.5-0.0-0.1-0.50.5-0.1-0.1-0.20.0
Progressive ratio test 2 breakpoint0.20.30.7-0.8-0.8-0.80.6-0.6-0.60.6-0.60.60.60.2-0.2-0.50.50.5-0.8-0.2-0.4-0.30.3-0.3-0.30.00.3
Progressive ratio test 2 inactive lever presses0.10.20.8-0.9-0.9-0.90.1-0.1-0.10.2-0.20.60.5-0.10.1-0.50.40.3-0.60.2-0.20.1-0.1-0.0-0.1-0.20.2
Incentive Sensitization - Responses0.10.10.20.0-0.0-0.1-0.30.40.4-0.30.3-0.2-0.1-0.40.40.3-0.2-0.2-0.30.40.30.2-0.20.30.3-0.4-0.2
Incentive Sensitization - Breakpoint0.10.10.20.0-0.0-0.0-0.40.50.5-0.40.4-0.2-0.1-0.50.50.3-0.2-0.2-0.30.40.30.3-0.30.30.3-0.4-0.2
Sum of active levers in priming session hrs 5-60.70.61.2-0.5-0.6-0.61.0-0.9-0.91.0-1.00.61.10.5-0.5-0.71.00.8-1.1-0.8-1.0-0.40.4-0.9-0.90.80.8
Progressive ratio0.30.41.60.90.70.70.4-0.5-0.40.2-0.2-0.8-0.41.2-1.20.5-0.2-0.60.8-0.30.4-0.90.9-0.00.10.2-0.4
Food seeking constrained by brief footshock0.10.10.30.60.30.3-0.40.40.4-0.30.3-0.5-0.00.0-0.00.2-0.1-0.30.1-0.00.00.4-0.4-0.1-0.10.20.1
Seeking ratio, punishment vs. effort0.30.41.2-0.4-0.4-0.5-0.40.60.4-0.20.20.50.5-1.11.1-0.50.30.5-0.90.1-0.60.9-0.9-0.3-0.30.20.7
Retroperitoneal fat weight2.99.625.2-5.0-5.0-5.02.3-1.8-2.22.6-2.64.63.5-0.50.5-4.13.64.1-3.5-1.1-3.40.3-0.3-2.2-2.61.13.1
Reaction time number correct6.59.413.4-0.8-1.4-1.63.2-3.1-3.23.4-3.42.42.82.9-2.9-2.93.42.9-3.5-3.6-3.0-3.43.4-3.7-3.63.63.3
Reaction time mean minus median0.81.01.60.50.60.7-1.11.11.1-1.21.2-1.0-1.1-0.40.41.0-1.2-1.01.31.21.20.5-0.51.21.2-1.2-1.1
Reaction time mean minus median AUC0.50.71.3-0.3-0.2-0.1-1.11.11.0-1.01.0-0.3-0.6-1.01.00.4-0.7-0.40.81.10.61.1-1.10.90.8-1.0-0.6
Reaction time num false alarms0.10.10.60.50.50.50.1-0.3-0.20.1-0.0-0.2-0.80.3-0.30.3-0.3-0.20.5-0.20.2-0.30.30.00.10.1-0.3
Reaction time num false alarms AUC0.10.20.90.80.80.80.0-0.2-0.2-0.00.0-0.3-1.00.5-0.50.3-0.4-0.30.6-0.30.3-0.50.5-0.00.00.2-0.2
Reaction time trials correct on left6.59.413.4-0.8-1.4-1.63.2-3.1-3.23.4-3.42.42.82.9-2.9-2.93.42.9-3.5-3.6-3.0-3.43.4-3.7-3.63.63.3
Reaction time trials on left6.79.513.8-0.8-1.4-1.63.2-3.1-3.23.4-3.42.42.92.9-2.9-3.03.43.0-3.5-3.6-3.1-3.43.4-3.7-3.73.63.4
Reaction time mean0.20.30.6-0.4-0.5-0.50.3-0.2-0.30.4-0.50.60.50.2-0.2-0.80.70.7-0.4-0.5-0.70.0-0.0-0.7-0.70.60.8
Reaction time mean AUC0.40.50.9-0.5-0.6-0.60.6-0.5-0.60.7-0.70.70.80.5-0.5-0.90.90.8-0.7-0.7-0.9-0.20.2-0.9-0.90.80.9
Median of all reaction times0.50.71.5-0.6-0.7-0.70.6-0.5-0.60.8-0.80.90.80.4-0.4-1.11.11.0-0.8-0.9-1.1-0.10.1-1.1-1.11.01.2
Reaction time omissions0.20.30.5-0.6-0.7-0.7-0.40.50.4-0.10.10.60.6-0.70.7-0.70.50.6-0.60.1-0.50.5-0.5-0.3-0.40.20.7
Reaction time false alarm rate1.92.75.11.11.51.5-1.61.41.5-1.71.7-1.5-2.3-1.01.01.8-2.0-1.82.21.51.81.2-1.21.81.9-1.6-1.9
Reaction time premature initiation rate0.50.71.91.31.41.40.7-1.0-0.80.5-0.4-0.8-0.91.1-1.10.6-0.5-0.60.6-0.70.4-0.90.9-0.00.20.4-0.7
Reaction time premature initiations2.73.97.70.70.40.32.5-2.7-2.52.3-2.30.70.92.7-2.7-1.21.41.2-1.4-2.6-1.4-2.82.8-2.1-1.92.31.2
Std. dev. reaction times0.10.10.50.70.60.6-0.30.30.3-0.20.2-0.4-0.50.5-0.50.1-0.2-0.20.4-0.20.2-0.30.3-0.1-0.00.3-0.0
Reaction time trials completed6.79.513.8-0.8-1.4-1.63.2-3.1-3.23.4-3.42.42.92.9-2.9-3.03.43.0-3.5-3.6-3.1-3.43.4-3.7-3.73.63.4
Reaction time trials AUC7.010.114.2-0.9-1.5-1.73.4-3.2-3.33.5-3.62.52.93.1-3.1-3.03.53.1-3.5-3.7-3.1-3.53.5-3.8-3.73.73.4
Run reversals in cocaine runway, females0.60.62.10.60.40.30.5-0.6-0.60.7-0.70.30.20.8-0.8-0.50.70.5-0.5-1.3-0.9-0.80.8-1.2-1.11.41.1
Run reversals in cocaine runway, males0.30.31.2-0.4-0.3-0.3-0.20.20.2-0.40.4-0.4-0.30.0-0.00.8-0.5-0.70.60.90.9-0.10.10.90.8-1.1-0.9
Latency to leave start box in cocaine runway0.50.52.01.01.00.90.3-0.4-0.30.1-0.1-0.8-0.21.2-1.20.7-0.3-0.70.1-0.40.5-1.41.4-0.00.10.2-0.4
Latency to leave start box in cocaine runway, F0.50.62.40.30.30.20.8-0.8-0.80.7-0.70.10.21.3-1.3-0.20.40.2-0.3-0.9-0.2-1.61.6-0.7-0.60.70.3
Latency to leave start box in cocaine runway, M0.50.51.00.70.80.70.5-0.6-0.40.2-0.1-1.0-0.20.9-0.91.0-0.5-1.00.20.00.7-0.90.90.50.6-0.4-1.0
Std. dev. time between licks in bursts2.73.26.4-1.0-1.3-1.41.8-1.7-1.81.9-1.91.82.41.2-1.2-2.02.02.0-2.5-1.8-2.1-1.01.0-2.0-2.01.92.0
Total sessions with >9 infusions0.40.51.01.00.90.9-0.90.90.9-0.80.8-1.0-0.4-0.40.40.8-0.7-0.80.10.50.60.3-0.30.50.5-0.3-0.5
Short access day 1 total inactive lever presses0.10.10.2-0.5-0.5-0.5-0.10.20.2-0.10.10.20.3-0.30.3-0.20.00.0-0.40.40.00.5-0.50.20.1-0.4-0.0
Short access day 10 total inactive lever presses1.41.65.3-2.3-2.3-2.30.5-0.3-0.50.7-0.71.91.4-1.01.0-1.51.31.6-1.10.0-1.30.9-0.9-0.6-0.80.11.2
Short access day 1 total infusions0.50.51.61.31.21.2-0.80.70.7-0.80.7-1.1-0.90.0-0.00.9-0.8-0.80.50.20.7-0.00.00.40.5-0.1-0.5
Short access day 10 total infusions0.10.10.5-0.7-0.7-0.70.4-0.3-0.30.3-0.30.30.60.1-0.1-0.10.20.1-0.60.2-0.0-0.10.10.10.1-0.3-0.1
Short access total infusions0.00.00.10.20.20.20.1-0.1-0.0-0.00.0-0.40.10.3-0.30.3-0.2-0.3-0.10.00.2-0.30.30.10.2-0.1-0.2
Short access day 1 locomotion0.91.01.80.70.70.7-1.01.01.0-1.11.1-1.2-1.0-0.40.41.3-1.2-1.20.71.01.30.5-0.51.11.1-1.1-1.1
Short access day 10 total locomotion0.70.81.20.50.50.6-0.90.80.9-1.01.0-0.9-0.9-0.50.51.1-1.0-1.00.91.01.10.4-0.41.01.0-1.0-1.0
Short access total locomotion1.41.52.81.01.01.1-1.21.11.2-1.31.3-1.6-1.2-0.40.41.7-1.5-1.61.11.21.60.4-0.41.41.4-1.3-1.4
One hour access (0.3 mA shock)1.41.62.4-1.3-1.4-1.41.6-1.5-1.51.5-1.51.31.51.1-1.1-1.31.41.2-1.4-1.0-1.2-1.01.0-1.1-1.10.81.0
Compulsive drug intake1.11.11.8-1.1-1.1-1.11.2-1.2-1.21.2-1.21.31.00.7-0.7-1.11.21.2-1.1-0.9-1.2-0.60.6-1.0-1.10.91.0
One hour access (shock baseline)0.10.10.2-0.4-0.4-0.40.2-0.2-0.10.1-0.1-0.10.40.2-0.20.10.0-0.2-0.20.30.2-0.30.30.30.2-0.4-0.3
Social response proportion0.20.20.70.0-0.0-0.00.3-0.4-0.40.5-0.50.50.2-0.10.1-0.60.50.6-0.2-0.7-0.90.2-0.2-0.7-0.70.80.7
Social responses0.30.41.0-0.5-0.6-0.60.4-0.3-0.50.5-0.61.00.4-0.20.2-0.90.71.0-0.3-0.6-0.90.2-0.2-0.7-0.80.70.9
Social time0.30.40.80.2-0.1-0.00.8-0.8-0.80.8-0.80.40.70.5-0.5-0.60.60.7-0.4-0.9-0.9-0.50.5-0.8-0.70.90.6
Soleus weight0.51.45.5-2.4-2.1-2.01.8-1.8-1.71.4-1.41.40.7-0.00.0-1.00.91.00.10.0-0.80.1-0.10.0-0.1-0.5-0.1
Bone: stiffness0.30.51.9-1.0-0.8-0.8-0.70.80.7-0.50.50.60.2-1.41.4-0.30.10.3-0.20.7-0.21.3-1.30.30.2-0.50.2
Tibialis anterior weight0.10.31.20.10.10.10.9-1.0-0.90.7-0.70.1-0.10.8-0.8-0.10.20.10.0-0.6-0.1-1.11.1-0.3-0.30.4-0.0
Time to tail flick, vehicle, before self-admin0.10.10.2-0.5-0.3-0.30.4-0.5-0.40.3-0.30.10.00.2-0.20.20.1-0.20.10.00.0-0.30.30.10.1-0.2-0.2
Time to tail flick, vehicle, after self-admin1.31.42.71.51.61.6-1.10.91.0-1.21.2-1.4-1.6-0.20.21.2-1.5-1.31.40.81.4-0.00.01.11.2-0.8-1.3
Time to tail flick, test, before self-admin0.10.10.20.10.10.1-0.30.30.3-0.30.3-0.2-0.4-0.10.10.1-0.3-0.10.30.40.4-0.00.00.40.4-0.4-0.4
Time to tail flick, test, after self-admin0.30.31.0-0.2-0.2-0.2-0.80.80.7-0.50.50.2-0.2-1.01.0-0.10.00.10.30.2-0.31.0-1.0-0.1-0.10.10.5
Delta time to tail flick, vehicle, before/after SA0.30.30.60.10.00.00.6-0.6-0.60.6-0.60.40.20.7-0.7-0.80.40.7-0.4-0.6-0.4-0.80.8-0.5-0.50.60.3
Delta time to tail flick, test, before/after SA0.30.30.80.50.50.4-0.90.90.8-0.60.6-0.3-0.3-0.80.80.4-0.3-0.30.30.1-0.00.9-0.9-0.0-0.00.20.3
Tibia length4.613.141.2-5.2-4.6-4.5-3.13.93.3-2.42.32.51.1-6.46.4-1.20.41.2-0.53.8-0.76.3-6.31.71.0-2.90.8
Ambulatory time before self-admin1.11.23.0-1.6-1.7-1.6-0.40.70.4-0.10.11.21.0-1.71.7-1.20.71.0-0.70.5-0.91.7-1.7-0.2-0.4-0.20.9
Ambulatory time after self-admin1.51.62.8-0.9-1.0-1.11.4-1.3-1.31.5-1.51.31.50.7-0.7-1.31.51.3-1.7-1.3-1.6-0.60.6-1.4-1.41.31.4
Bone: tissue strength2.62.64.8-1.6-1.7-1.72.2-2.2-2.22.0-2.01.71.91.4-1.4-1.61.61.7-1.3-1.2-1.5-1.01.0-1.2-1.20.91.0
Total heroin consumption0.40.42.0-0.2-0.2-0.2-0.70.80.8-0.50.50.10.4-1.21.2-0.30.00.3-0.30.4-0.31.4-1.40.10.1-0.10.3
Bone: trabecular number0.10.10.60.40.40.4-0.0-0.00.0-0.20.2-0.5-0.6-0.10.10.4-0.4-0.40.80.20.4-0.00.00.40.4-0.3-0.5
Bone: trabecular spacing3.74.710.7-1.2-1.6-1.81.3-1.0-1.31.8-1.92.62.80.4-0.4-2.82.72.8-3.0-2.2-2.9-0.40.4-2.8-2.92.73.3
Bone: trabecular thickness0.91.13.9-0.00.30.40.1-0.20.0-0.40.5-1.0-1.2-0.10.11.2-1.2-1.31.71.21.40.1-0.11.61.6-1.7-2.0
Bone: trabecular tissue density0.70.91.81.01.11.1-1.31.31.3-1.21.2-0.9-1.0-0.80.81.0-1.0-1.00.60.70.90.8-0.80.70.8-0.5-0.6
Water consumed over 24 hours0.20.20.6-0.00.10.2-0.10.10.2-0.30.3-0.4-0.0-0.00.00.6-0.5-0.60.40.60.60.4-0.40.70.7-0.7-0.8
Number of responses in last shaping day0.70.72.0-1.0-1.0-1.0-0.60.80.7-0.50.50.30.7-1.41.4-0.1-0.00.2-0.81.10.01.4-1.40.60.5-0.9-0.1