Hub : Genes

Slc25a17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Slc25a17 0.54 0.15 0.0e+00 0.34 0.34 0.34 0.36 2.1e-18 1.3e-18 1.1e-18 4.5e-20
2 IL mRNA stability Slc25a17 0.17 0.1 7.2e-03 0.11 0.01 0.01 0.03 1.2e-03 1.8e-01 2.2e-01 7.2e-02
3 Brain gene expression Slc25a17 0.32 0.11 0.0e+00 0.37 0.39 0.38 0.39 1.9e-36 4.3e-38 1.4e-37 1.9e-38
4 Adipose gene expression Slc25a17 0.21 0.08 0.0e+00 0.18 0.18 0.17 0.18 4.6e-20 4.1e-19 6.8e-19 2.6e-19
5 PL gene expression Slc25a17 0.29 0.1 0.0e+00 0.33 0.36 0.36 0.36 6.3e-37 3.2e-41 2.0e-40 1.6e-40
6 OFC gene expression Slc25a17 0.48 0.15 4.1e-09 0.27 0.29 0.24 0.34 4.3e-07 1.7e-07 1.7e-06 8.4e-09
7 IC gene expression Slc25a17 0.36 0.12 0.0e+00 0.37 0.38 0.4 0.38 1.3e-16 4.0e-17 4.3e-18 3.1e-17
8 Brain mRNA stability Slc25a17 0.04 0.02 8.9e-04 0.02 0.02 0.01 0.01 7.9e-03 8.6e-03 2.3e-02 6.0e-02
9 Adipose mRNA stability Slc25a17 0.03 0.02 2.1e-03 0 0.01 0 0 1.2e-01 1.4e-02 3.4e-01 1.3e-01
10 NAcc gene expression Slc25a17 0.19 0.07 0.0e+00 0.25 0.18 0.25 0.25 2.8e-38 3.2e-27 2.9e-38 8.3e-38
11 LHb gene expression Slc25a17 0.17 0.1 3.5e-03 0.11 0.05 0.01 0.06 1.7e-03 2.1e-02 1.7e-01 1.7e-02
12 Liver gene expression Slc25a17 0.17 0.08 0.0e+00 0.11 0.12 0.12 0.11 8.0e-12 5.9e-13 1.5e-13 1.6e-12
13 IL gene expression Slc25a17 0.3 0.14 5.1e-05 0.17 0.12 0.15 0.16 7.8e-05 1.1e-03 1.5e-04 1.2e-04
14 pVTA gene expression Slc25a17 0.3 0.12 0.0e+00 0.27 0.22 0.28 0.09 4.1e-22 1.1e-17 3.0e-22 1.5e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.20.30.7-0.30.4-0.5-0.3-0.3-0.6-0.20.70.2-0.7-0.7-0.9-0.6-0.4
Area under the delay curve0.40.41.1-0.90.9-0.7-0.8-0.4-0.5-0.80.6-0.2-0.5-0.2-0.5-0.4-1.0
BMI with tail1.13.86.62.2-2.22.02.62.01.81.9-1.91.91.71.91.41.51.9
BMI without tail0.00.10.30.3-0.30.10.50.1-0.1-0.10.10.5-0.20.2-0.3-0.50.1
Body weight1.56.78.32.9-2.62.82.82.72.72.5-2.72.42.72.62.22.02.7
Weight adjusted by age0.10.10.40.10.60.2-0.5-0.20.2-0.20.3-0.70.3-0.1-0.20.10.3
Bone surface0.30.61.2-0.81.0-0.6-0.9-0.6-0.7-0.30.7-0.2-0.7-0.8-1.1-0.7-0.9
Bone volume0.10.10.3-0.20.3-0.2-0.2-0.1-0.30.10.30.3-0.3-0.4-0.6-0.3-0.3
Breakpoint value in progressive ratio session0.10.10.50.3-0.20.20.10.40.1-0.1-0.10.70.2-0.00.0-0.00.1
Number of licking bursts0.81.32.1-1.11.4-1.2-1.3-1.1-1.0-1.31.0-1.1-1.0-0.9-1.3-0.9-1.1
Context. condit. distance diff. score6.68.010.22.5-2.93.02.72.52.93.1-3.01.13.02.93.23.03.0
Locomotion velocity, session 10.20.20.9-0.60.9-0.4-0.9-0.3-0.3-0.50.3-0.3-0.20.0-0.4-0.0-0.6
Locomotion distance, session 13.34.27.1-2.42.7-2.2-2.7-2.0-2.0-2.01.9-1.7-1.8-1.6-1.9-1.7-2.0
Locomotion velocity, session 20.20.20.40.5-0.30.50.40.60.40.2-0.30.70.50.50.40.40.3
Locomotion distance, session 22.84.06.2-1.92.5-2.1-2.2-1.7-2.2-2.12.0-0.6-2.0-1.7-2.5-1.9-1.8
Locomotion velocity, session 30.10.20.8-0.0-0.10.3-0.2-0.10.40.6-0.4-0.90.40.00.60.20.4
Locomotion distance, session 31.92.05.6-1.81.7-1.3-1.9-1.7-1.1-1.10.9-2.4-1.0-1.2-0.8-1.1-1.1
Stereotopy head waving bouts, day 30.91.02.31.2-1.01.01.01.31.00.7-0.91.51.00.80.80.80.6
Stereotopy head waving duration, day 33.74.46.32.4-2.42.12.32.32.01.9-1.92.51.91.81.91.91.6
Locomotion velocity, session 70.20.20.30.3-0.30.50.20.30.50.4-0.5-0.10.50.60.60.50.5
Locomotion distance, session 70.00.00.1-0.20.3-0.0-0.30.00.00.1-0.20.00.1-0.00.00.10.3
Stereotopy head waving bouts, day 71.82.03.31.4-1.51.51.51.21.61.5-1.50.41.51.31.81.51.0
Stereotopy head waving duration, day 72.02.44.01.6-1.91.61.91.31.61.5-1.50.71.41.32.01.41.1
Locomotion velocity, session 81.51.82.41.3-1.01.51.11.51.31.1-1.41.31.51.51.01.41.5
Locomotion distance, session 80.60.91.60.7-0.91.00.80.70.81.3-0.90.21.01.01.11.01.2
Degree of sensitization distance3.83.97.02.2-2.32.02.32.21.71.6-1.72.61.71.81.61.81.8
Degree of sensitization stereotypy1.31.42.41.1-1.21.31.21.01.31.3-1.30.21.21.21.61.31.0
Conditioned locomotion0.50.61.10.7-0.80.80.90.70.70.7-0.80.40.70.91.10.90.7
Cocaine response after cond. corrected0.20.20.40.5-0.40.50.10.50.40.6-0.40.60.40.10.60.20.5
Cocaine response after cond. not corrected0.10.10.30.4-0.40.30.00.30.10.5-0.10.50.2-0.10.4-0.10.3
Cocaine response before conditioning0.30.30.6-0.50.3-0.6-0.3-0.7-0.8-0.30.7-0.5-0.6-0.7-0.4-0.7-0.4
Saline control response0.10.10.5-0.4-0.0-0.2-0.0-0.4-0.30.30.3-0.7-0.1-0.10.3-0.1-0.3
Bone: connectivity density0.00.00.2-0.00.2-0.1-0.1-0.0-0.20.30.20.3-0.2-0.2-0.50.0-0.0
Bone: cortical apparent density1.31.83.4-1.51.3-1.4-1.4-1.5-1.3-1.41.2-1.8-1.1-1.2-1.4-0.9-1.1
Bone: cortical area1.52.34.31.7-1.51.61.71.81.51.5-1.32.11.41.61.01.31.2
Bone: cortical porosity0.70.81.51.0-1.20.91.00.90.71.2-0.61.10.60.31.00.41.0
Bone: cortical porosity2.12.33.41.7-1.81.61.71.61.31.8-1.41.91.21.11.61.01.4
Bone: cortical thickness0.30.51.30.8-0.60.70.80.90.70.7-0.51.20.60.8-0.10.50.9
Bone: cortical thickness0.30.41.20.7-0.30.40.50.80.50.2-0.41.10.40.8-0.11.00.7
Bone: cortical tissue density1.21.73.3-1.51.3-1.3-1.4-1.5-1.2-1.41.1-1.8-1.1-1.1-1.3-0.8-1.0
Condit. Reinf. active minus inactive responses0.30.30.7-0.50.6-0.6-0.5-0.5-0.5-0.80.4-0.3-0.5-0.2-0.8-0.3-0.6
Condit. Reinf. active-inactive response ratio0.10.20.40.2-0.30.30.30.20.50.4-0.5-0.20.40.60.40.60.2
Condit. Reinf. active responses1.72.12.7-1.51.3-1.6-1.2-1.5-1.7-1.61.5-1.0-1.6-1.1-1.6-1.2-1.4
Condit. Reinf. inactive responses3.13.85.7-2.01.8-2.1-1.5-2.0-2.4-2.02.2-1.4-2.3-1.7-1.9-1.8-1.8
Incentive salience index mean0.60.71.6-0.80.9-0.9-0.8-0.8-0.9-1.00.8-0.5-0.8-0.4-1.2-0.6-0.8
Condit. Reinf. lever presses0.91.22.2-1.01.1-1.2-1.0-1.0-1.3-1.11.3-0.6-1.2-0.8-1.5-0.9-1.1
Condit. Reinf. active minus inactive responses0.10.10.6-0.20.5-0.2-0.20.00.0-0.70.00.3-0.10.2-0.70.3-0.5
Condit. Reinf. active-inactive response ratio0.10.20.80.3-0.00.30.20.50.4-0.4-0.40.90.30.4-0.40.50.1
Condit. Reinf. active responses0.20.30.90.3-0.10.40.30.60.6-0.0-0.50.50.60.90.00.90.0
Condit. Reinf. inactive responses0.30.51.10.4-0.30.50.40.60.80.6-0.80.30.91.10.71.00.3
Condit. Reinf. lever presses0.30.51.0-0.60.7-0.7-0.5-0.5-0.7-0.90.8-0.2-0.7-0.6-1.0-0.6-0.7
Condit. Reinf. lever reinforcers received0.10.10.50.2-0.00.20.20.40.4-0.2-0.30.50.30.7-0.20.7-0.1
Conditioned reinforcement - actives0.40.62.70.6-0.80.50.30.70.70.5-0.80.50.71.20.61.60.6
Conditioned reinforcement - inactives0.20.31.6-0.30.5-0.40.0-0.0-0.4-0.40.20.8-0.50.4-1.30.4-0.7
Conditioned locomotion1.92.44.01.7-1.81.41.71.71.21.2-1.72.01.31.70.81.91.2
Patch foraging indifference point 0 sec0.40.71.6-0.50.6-0.8-0.6-0.6-1.0-0.81.00.1-0.9-1.0-1.3-0.9-0.7
Patch foraging indifference point AUC0.60.92.7-1.21.6-0.9-1.3-0.8-0.6-0.90.6-1.0-0.6-0.6-0.9-0.8-0.9
Delay disc. indifference point, 0s delay1.01.12.61.0-1.41.01.31.20.70.9-0.81.60.81.10.90.71.0
Delay disc. indifference point, 16s delay1.31.52.8-1.31.5-1.2-1.3-1.0-1.0-1.30.9-0.8-1.1-1.1-1.1-1.2-1.7
Delay disc. indifference point, 2s delay0.00.00.1-0.20.2-0.20.10.1-0.0-0.2-0.00.3-0.00.40.00.2-0.2
Delay disc. indifference point, 24s delay0.40.51.8-0.61.3-0.4-1.3-0.20.1-0.60.2-0.4-0.1-0.2-0.5-0.4-1.1
Delay disc. indifference point, 4s delay0.20.20.4-0.50.5-0.5-0.3-0.2-0.4-0.60.40.2-0.40.2-0.60.2-0.5
Delay disc. indifference point, 8s delay0.80.91.7-1.21.2-1.1-1.1-0.9-0.8-1.11.1-0.6-0.9-0.7-0.7-0.7-1.3
Indifference point function ln k0.91.63.11.3-1.81.31.51.01.11.3-1.20.71.01.21.21.41.3
Indifference point function log k0.91.63.11.3-1.81.31.51.01.11.3-1.20.71.01.21.21.41.3
Patch foraging total patch changes 0 sec0.50.91.7-0.60.7-0.9-0.7-0.7-1.1-1.01.20.0-1.0-1.1-1.3-1.0-0.9
Patch foraging total patch changes 12 sec0.10.10.2-0.20.5-0.2-0.2-0.1-0.3-0.20.20.2-0.1-0.4-0.5-0.4-0.2
Patch foraging total patch changes 18 sec0.20.30.8-0.40.7-0.5-0.6-0.1-0.6-0.70.60.7-0.6-0.3-0.9-0.5-0.7
Patch foraging total patch changes 24 sec0.40.60.9-0.71.0-0.8-0.9-0.7-0.7-0.70.8-0.4-0.7-0.9-0.7-0.9-0.9
Patch foraging total patch changes 6 sec0.60.82.3-0.61.2-0.8-1.0-0.4-0.9-0.81.00.6-0.8-0.9-1.5-0.9-1.0
Patch foraging time to switch 0 sec0.10.20.70.5-0.70.30.60.3-0.10.50.00.8-0.1-0.30.5-0.20.2
Patch foraging water rate 0 sec0.10.20.8-0.30.5-0.6-0.3-0.3-0.4-0.50.50.0-0.5-0.2-0.9-0.4-0.3
Patch foraging water rate 12 sec0.40.91.5-0.90.7-1.1-0.8-1.0-0.9-1.20.9-0.9-1.1-0.5-0.9-0.7-1.1
Patch foraging water rate 18 sec1.11.83.0-1.01.4-1.3-1.4-1.0-1.1-1.51.4-0.6-1.2-1.5-1.7-1.7-1.3
Patch foraging water rate 24 sec0.10.10.20.5-0.40.30.20.40.3-0.2-0.10.40.20.4-0.20.30.2
Patch foraging water rate 6 sec1.31.93.7-1.61.4-1.5-1.4-1.6-1.3-1.01.1-1.9-1.5-0.9-1.3-1.3-1.3
Seeking ratio, delayed vs. immediate footshock2.32.85.6-1.41.7-1.6-1.7-1.5-1.8-1.91.9-1.0-1.6-1.9-2.4-1.8-1.1
Distance traveled before self-admin0.10.10.3-0.20.6-0.3-0.1-0.2-0.5-0.40.40.3-0.4-0.2-0.5-0.20.1
Distance traveled after self-admin0.20.31.3-0.10.4-0.4-0.10.0-0.6-0.60.61.0-0.5-0.1-1.1-0.3-0.3
Extensor digitorum longus weight0.10.60.9-0.60.3-0.8-0.4-0.8-0.9-0.70.9-0.4-0.9-0.9-0.8-0.9-0.7
Bone: elastic displacement0.00.00.10.1-0.10.10.10.10.30.2-0.2-0.10.1-0.00.1-0.20.0
Bone: elastic work2.73.55.72.1-2.02.02.02.11.81.9-1.72.41.71.61.61.41.7
Bone: endosteal estimation0.51.02.31.0-1.11.01.01.20.91.2-0.91.50.80.71.30.80.4
Bone: endosteal perimeter1.32.83.71.7-1.91.81.81.71.71.6-1.71.71.51.71.91.60.9
Epididymis fat weight3.110.512.53.4-3.53.43.43.23.43.3-3.12.53.23.03.52.93.3
Delta time in closed arm before/after self-admin0.20.20.50.60.20.40.10.50.70.2-0.40.40.60.60.40.50.6
Delta time in open arm before/after self-admin0.40.41.1-0.9-0.2-0.8-0.5-0.6-0.8-0.20.7-0.5-0.7-0.3-0.2-0.0-1.0
Diff in mean of infusions in LGA sessions0.30.30.70.50.50.80.00.70.70.5-0.60.60.80.30.2-0.10.9
Delay discount exponential model param0.50.51.31.0-1.00.80.90.50.50.9-0.70.40.60.30.60.41.1
Extinction: sum of active levers before priming1.21.32.41.2-1.01.11.11.41.31.0-1.11.61.10.91.10.91.0
Active lever presses in extinction session 60.30.30.60.7-0.60.60.40.70.60.5-0.30.80.50.20.40.20.5
Bone: final force1.82.86.01.9-1.41.91.42.11.71.8-1.52.41.61.51.01.41.6
Bone: final moment1.93.06.52.0-1.51.91.52.11.71.9-1.62.51.61.51.01.51.6
Food consumed during 24 hour testing period1.72.44.01.8-1.41.61.41.81.61.2-1.52.01.61.41.01.31.6
Glucose0.10.10.40.3-0.2-0.10.50.1-0.3-0.40.40.6-0.3-0.3-0.4-0.6-0.0
Heart weight6.39.813.43.2-3.42.93.63.22.73.5-2.93.42.63.72.53.42.4
Delay discount hyperbolic model param0.40.41.10.9-0.90.70.70.50.50.8-0.60.30.60.10.50.31.0
Intermittent access intake day 1-15 change0.10.30.7-0.60.3-0.6-0.3-0.7-0.5-0.70.4-0.6-0.8-0.5-0.4-0.3-0.5
Intermittent access intake escalation0.30.61.0-0.80.6-0.8-0.6-0.9-0.7-0.90.6-0.9-1.0-0.6-0.5-0.5-0.7
Intermittent access intake escalation 20.40.40.8-0.60.4-0.6-0.6-0.8-0.6-0.70.7-0.7-0.9-0.7-0.4-0.5-0.7
Intermitt. access day 1 inactive lever presses0.20.92.51.1-1.20.81.21.00.50.9-0.61.60.50.9-0.00.91.0
Intermitt. access day 15 inactive lever presses0.10.21.3-0.00.2-0.20.5-0.0-0.5-0.2-0.10.6-0.40.5-1.10.4-0.2
Intermitt. access escalation Index0.40.51.4-0.61.2-0.6-0.6-0.7-0.7-0.70.9-0.6-0.6-0.3-1.0-0.2-0.6
Intermittent access day 1 total infusions0.40.71.80.7-0.30.70.81.00.70.5-0.81.40.81.20.41.10.5
Intermittent access day 15 total infusions0.20.20.6-0.70.6-0.6-0.4-0.5-0.5-0.70.3-0.3-0.60.1-0.30.2-0.8
Intermittent access terminal intake (last 3 days)0.00.00.2-0.20.2-0.2-0.3-0.1-0.0-0.2-0.1-0.1-0.20.10.20.1-0.4
Intermittent access total infusions0.20.31.00.4-0.10.40.30.60.40.3-0.51.00.40.70.30.60.1
Intermittent access day 1 locomotion0.20.31.90.5-0.50.20.60.6-0.10.3-0.31.40.20.6-0.10.50.4
Intermittent access day 15 total locomotion0.20.41.70.6-0.70.50.60.80.40.6-0.81.30.50.60.40.40.3
Intermittent access total locomotion0.60.72.60.8-0.80.60.71.10.60.7-0.91.60.70.60.60.50.5
Intermittent access standard deviation0.61.33.31.4-1.41.11.41.20.80.9-0.81.80.60.91.11.01.0
Left kidney weight10.147.054.66.9-6.87.17.17.07.06.9-7.25.96.97.46.27.26.1
Right kidney weight12.657.364.67.8-7.77.98.07.97.77.5-7.86.87.67.86.77.77.0
Cocaine induced anxiety1.82.64.42.1-1.21.91.42.02.01.5-1.71.72.00.81.30.71.6
Post-drug Anxiety0.10.10.40.50.00.40.20.30.60.2-0.40.00.6-0.10.4-0.30.4
Baseline Anxiety3.33.86.2-2.51.8-2.2-1.7-2.3-2.1-2.01.9-2.3-2.2-1.3-1.5-1.2-1.9
Tail length0.51.83.1-1.31.4-1.4-1.5-1.5-1.3-1.11.5-1.3-1.4-1.5-0.9-1.8-0.9
Length with tail0.21.01.71.0-0.71.10.80.91.21.3-1.10.51.10.81.10.51.3
Length without tail2.78.611.13.0-2.83.13.03.13.03.3-3.12.73.02.62.62.62.9
Times rat made contact with spout0.30.40.70.5-0.20.50.20.60.80.5-0.90.50.70.80.10.80.7
Lifetime Intake0.80.92.90.9-0.40.80.81.20.80.6-1.01.70.81.30.41.10.6
Liver weight, left0.71.13.00.6-0.91.00.80.71.20.8-1.1-0.51.31.31.71.10.9
Liver weight, right2.03.46.61.6-2.12.01.71.42.11.9-1.8-0.12.11.92.61.72.0
Locomotor activity2.13.34.31.7-2.01.92.01.71.82.1-2.01.41.61.91.92.01.4
Locomotor testing distance0.00.10.2-0.20.1-0.3-0.3-0.3-0.2-0.00.2-0.3-0.4-0.2-0.1-0.1-0.3
Locomotor testing rearing1.12.33.81.4-1.51.51.31.41.41.9-1.41.01.41.71.71.91.4
Locomotion in novel chamber1.41.74.0-1.70.1-1.7-0.8-1.8-1.7-1.01.2-2.0-1.6-0.3-0.70.2-1.4
Locomotion in novel chamber post-restriction0.50.91.4-1.20.8-0.8-0.8-1.1-1.0-0.70.8-1.1-1.1-1.1-0.5-1.0-0.9
Fecal boli incidents, locomotor time 10.20.30.7-0.20.5-0.5-0.5-0.1-0.3-0.60.30.5-0.4-0.7-0.5-0.8-0.8
Change in fecal boli incidents, locomotor task0.50.51.10.3-0.10.70.20.30.90.6-1.0-0.70.91.00.71.10.8
Time >=10cm from walls, locomotor time 10.50.51.11.0-0.60.80.40.90.80.5-0.51.00.90.20.50.40.8
Bouts of movement, locomotor time 11.01.12.21.1-0.71.20.71.11.51.0-1.00.71.40.71.10.61.5
Total resting periods, locomotor time 10.70.81.71.0-0.51.00.71.01.30.8-0.90.81.20.50.70.31.3
Rest time, locomotor task time 11.01.22.21.2-1.11.11.51.21.21.1-1.21.21.00.90.70.91.1
Distance moved, locomotor task time 10.10.20.70.4-0.60.3-0.10.20.30.5-0.0-0.20.30.50.80.70.4
Vertical activity count, locomotor time 10.00.10.3-0.0-0.0-0.2-0.5-0.1-0.2-0.30.40.0-0.2-0.10.00.0-0.2
Time >=10cm from walls, locomotor time 20.10.10.4-0.00.3-0.1-0.3-0.1-0.2-0.30.50.2-0.3-0.4-0.6-0.50.0
Bouts of movement, locomotor time 20.30.51.00.6-0.70.50.80.60.50.8-0.70.40.70.90.01.01.0
Total resting periods, locomotor time 20.20.40.80.5-0.50.50.70.60.50.7-0.70.60.60.7-0.10.90.9
Rest time, locomotor task time 20.00.00.1-0.20.4-0.20.0-0.1-0.1-0.3-0.2-0.1-0.0-0.1-0.2-0.2-0.1
Distance moved, locomotor task time 20.40.51.00.6-0.90.50.40.40.51.0-0.30.20.40.90.90.90.8
Vertical activity count, locomotor time 20.10.10.40.4-0.60.20.00.40.30.4-0.20.50.20.40.60.20.3
Light reinforcement 10.00.10.5-0.10.1-0.3-0.3-0.1-0.2-0.20.40.0-0.30.1-0.10.6-0.7
Light reinforcement 20.61.01.51.0-1.11.11.00.81.21.1-0.90.21.00.81.20.71.2
Bone: marrow area0.51.12.61.1-1.11.11.01.30.91.2-0.91.60.90.71.30.90.4
Bone: maximum diameter3.76.99.92.8-2.72.72.82.92.62.4-2.53.12.62.82.22.52.0
Bone: maximum force2.54.49.32.3-1.82.21.92.52.12.2-1.93.01.91.91.32.01.9
Bone: maximum moment2.84.910.02.4-1.92.32.02.62.22.4-2.03.22.02.01.42.12.0
Mean time between licks in bursts0.30.71.0-0.70.6-0.8-0.5-0.9-0.9-0.80.9-0.7-1.0-1.0-0.8-0.9-0.7
Mean num. licks in bursts1.72.73.21.5-1.61.71.51.61.71.7-1.81.21.71.71.61.71.7
Cd content in liver0.70.82.50.5-0.40.90.50.81.20.6-1.10.11.11.30.71.60.7
Co content in liver0.10.10.80.20.4-0.0-0.00.2-0.0-0.2-0.10.5-0.00.1-0.9-0.3-0.0
Cu content in liver6.98.210.0-2.72.8-3.0-2.7-2.7-3.1-3.03.1-1.6-3.0-3.0-3.1-3.2-2.9
Fe content in liver0.91.13.81.3-1.20.91.31.30.61.0-0.81.90.80.70.70.80.8
K content in liver1.51.52.6-1.21.3-1.3-1.2-1.3-1.2-0.71.2-1.1-1.2-1.3-1.3-1.6-0.9
Mg content in liver1.21.22.4-1.01.2-1.1-1.0-1.0-1.1-0.71.2-0.5-1.1-1.1-1.4-1.5-0.9
Mn content in liver0.10.10.8-0.40.4-0.2-0.5-0.4-0.10.30.1-0.9-0.0-0.10.1-0.1-0.1
Na content in liver2.02.13.0-1.41.3-1.6-1.2-1.5-1.7-1.31.7-0.8-1.7-1.6-1.4-1.7-1.3
Rb content in liver0.10.10.60.20.20.1-0.10.50.30.3-0.30.80.20.3-0.40.30.1
Se content in liver0.50.61.4-0.90.7-0.8-0.9-0.9-0.7-0.40.7-1.2-0.6-0.8-0.3-0.7-0.5
Sr content in liver2.82.42.8-1.61.5-1.6-1.5-1.7-1.6-1.61.7-1.6-1.6-1.6-1.3-1.6-1.2
Zn content in liver0.20.20.4-0.60.7-0.3-0.4-0.4-0.3-0.20.3-0.5-0.1-0.2-0.5-0.6-0.6
Bone: minimum diameter0.40.81.70.9-1.00.81.01.00.80.8-0.81.30.60.91.00.70.3
Time in familiar zone, hab. session 10.10.10.20.10.30.2-0.40.30.40.1-0.30.20.50.2-0.10.2-0.2
Time in novel zone, hab. session 10.60.61.70.8-1.30.61.30.60.40.6-0.50.60.30.51.00.50.9
Total zone transitions, hab. session 15.27.210.3-3.23.1-2.8-3.1-2.9-2.6-2.52.2-3.2-2.5-2.1-2.4-2.1-2.5
Total locomotion distance, hab. session 13.04.37.9-2.52.2-2.2-2.3-2.4-2.0-1.51.7-2.8-1.9-1.7-1.4-1.7-2.0
Locomotion velocity, hab. session 13.54.96.9-2.62.4-2.4-2.5-2.5-2.2-1.81.9-2.6-2.1-1.9-1.7-1.9-2.2
Time in familiar zone, hab. session 20.10.10.8-0.3-0.1-0.2-0.1-0.4-0.1-0.10.0-0.9-0.1-0.00.40.1-0.3
Time in novel zone, hab. session 20.10.10.70.40.00.20.20.40.20.2-0.00.80.20.1-0.1-0.00.4
Total zone transitions, hab. session 21.82.44.3-1.82.1-1.6-1.7-1.4-1.6-1.61.3-0.8-1.5-1.0-2.0-1.1-1.6
Total locomotion distance, hab. session 21.31.72.4-1.41.5-1.5-1.2-1.2-1.5-1.31.2-0.5-1.5-1.0-1.6-1.1-1.5
Locomotion velocity, hab. session 22.12.93.8-1.82.0-1.9-1.6-1.6-1.9-1.71.6-0.8-1.9-1.4-1.9-1.5-1.8
Novel to familiar place preference ratio2.52.83.41.7-1.71.81.61.61.81.8-1.70.91.91.81.81.61.5
Novelty place preference3.53.84.91.9-1.92.01.81.82.22.1-2.00.92.22.12.11.91.9
Time in novel zone, NPP test4.34.65.92.1-2.12.22.12.02.42.3-2.21.12.42.32.32.22.0
Total zone transitions, NPP test4.76.810.3-3.13.2-2.8-3.0-2.7-2.6-2.32.2-2.7-2.3-2.1-2.6-2.1-2.5
Total locomotion distance, NPP test2.33.14.4-2.12.1-2.0-2.0-1.8-1.9-1.41.5-1.6-1.7-1.4-1.8-1.5-1.7
Locomotion velocity, NPP test3.14.45.9-2.42.4-2.3-2.3-2.2-2.2-1.81.9-1.9-2.1-1.8-2.0-1.9-2.0
Intraocular pressure0.30.41.30.5-0.40.60.30.50.80.6-0.60.00.80.81.10.90.8
Delta distance traveled before/after self-admin0.20.20.60.4-0.30.30.30.60.50.5-0.50.80.50.70.20.60.1
Delta ambulatory time before/after self-admin0.20.30.80.5-0.10.50.20.70.60.5-0.50.90.60.80.10.50.1
Parametrial fat weight0.00.10.80.1-0.20.20.1-0.10.20.2-0.1-0.70.30.00.9-0.30.2
Pavlov. Cond. lever latency0.40.61.00.6-0.70.80.70.70.81.0-1.00.50.70.60.80.80.8
Pavlov. Cond. magazine entry latency0.50.61.2-0.60.9-0.7-1.0-0.6-0.6-1.10.8-0.3-0.6-0.6-1.0-0.8-0.7
Pavlov. Cond. change in total contacts1.31.42.9-1.01.4-1.2-1.2-0.9-1.2-1.61.3-0.2-1.1-0.8-1.7-1.0-1.3
Pavlov. Cond. index score0.20.30.7-0.30.6-0.5-0.6-0.4-0.4-0.80.6-0.0-0.4-0.2-0.8-0.5-0.4
Pavlov. Cond. latency score0.20.20.6-0.30.5-0.5-0.5-0.4-0.4-0.70.6-0.1-0.4-0.2-0.7-0.4-0.4
Pavlov. Cond. lever contacts1.41.62.4-1.21.3-1.4-1.2-1.2-1.4-1.51.5-0.7-1.3-1.1-1.4-1.3-1.3
Pavlov. Cond. magazine entry number0.50.61.10.7-1.00.81.00.70.61.0-0.70.50.70.61.00.70.7
Pavlov. Cond. intertrial magazine entries1.01.21.9-1.01.1-1.2-1.0-0.9-1.1-1.11.2-0.3-1.2-1.0-1.4-1.0-1.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.50.8-0.6-0.8-0.5-0.5-0.90.7-0.3-0.4-0.4-0.9-0.6-0.6
Pavlov. Cond. response bias0.70.81.5-0.81.1-0.9-1.1-0.8-0.8-1.21.0-0.4-0.8-0.7-1.2-0.9-0.8
Pavlov. Cond. lever latency0.71.02.20.8-0.71.00.40.81.11.3-1.10.01.21.01.51.11.0
Pavlov. Cond. magazine entry latency2.32.85.1-1.41.7-1.7-1.5-1.3-1.8-2.01.7-0.2-1.9-1.9-2.2-1.9-1.5
Pavlov. Cond. change in total contacts0.40.62.3-0.00.4-0.3-0.00.1-0.5-1.40.61.3-0.7-0.5-1.5-0.6-0.7
Pavlov. Cond. index score1.41.94.1-1.11.3-1.3-1.0-1.1-1.4-1.81.4-0.1-1.6-1.5-2.0-1.5-1.3
Pavlov. Cond. latency score2.02.75.3-1.41.6-1.6-1.3-1.3-1.7-2.01.7-0.3-1.8-1.7-2.3-1.8-1.5
Pavlov. Cond. lever contacts1.01.42.7-0.90.9-1.1-0.5-1.0-1.3-1.41.3-0.2-1.4-1.2-1.7-1.3-1.2
Pavlov. Cond. magazine entry number1.31.63.11.1-1.31.21.11.01.21.7-1.20.21.41.31.81.41.2
Pavlov. Cond. intertrial magazine entries1.92.84.11.6-1.51.61.61.71.72.0-1.71.31.71.91.41.91.6
Pavlov. Cond. lever-magazine prob. diff.1.52.04.1-1.21.3-1.4-1.0-1.1-1.5-1.81.5-0.1-1.7-1.6-2.0-1.6-1.3
Pavlov. Cond. response bias0.91.22.9-0.80.9-1.0-0.5-0.8-1.2-1.61.20.2-1.3-1.1-1.7-1.1-1.2
Time in closed arm before self-admin4.05.18.4-2.02.0-2.2-2.1-1.9-2.6-2.22.9-0.4-2.4-2.8-2.0-2.9-2.2
Time in closed arm after self-admin0.10.10.40.10.20.2-0.00.2-0.00.10.20.60.1-0.20.4-0.30.3
Time in open arm before self-admin0.10.10.80.20.10.10.1-0.10.50.2-0.3-0.90.4-0.10.60.00.4
Time in open arm after self-admin0.30.31.3-0.8-0.2-0.6-0.4-0.7-0.5-0.20.3-1.1-0.5-0.40.1-0.2-0.7
Bone: periosteal estimation1.22.55.01.7-1.71.61.61.81.51.7-1.42.21.41.41.51.31.0
Bone: periosteal perimeter3.56.07.22.5-2.72.62.72.62.52.4-2.42.52.32.62.52.31.7
Bone: post-yield work0.30.41.60.6-0.10.50.30.80.60.4-0.61.20.50.7-0.00.70.5
Progressive ratio test 1 active lever presses0.30.31.10.60.30.50.10.80.70.2-0.51.10.60.60.30.50.3
Progressive ratio test 1 breakpoint0.20.20.80.50.40.4-0.10.70.70.2-0.40.90.60.50.30.40.2
Progressive ratio test 1 inactive lever presses0.40.62.70.7-0.70.30.90.80.20.4-0.41.60.21.1-0.31.00.3
Progressive ratio test 2 active lever presses0.10.10.50.10.50.2-0.30.50.3-0.0-0.40.70.40.5-0.10.40.1
Progressive ratio test 2 breakpoint0.10.10.40.10.60.2-0.40.40.3-0.1-0.40.60.40.5-0.10.30.1
Progressive ratio test 2 inactive lever presses0.30.51.0-0.81.0-0.9-0.9-0.6-0.9-0.60.6-0.2-0.8-0.3-0.7-0.3-0.7
Incentive Sensitization - Responses0.20.20.7-0.70.8-0.4-0.6-0.4-0.4-0.50.2-0.5-0.4-0.0-0.7-0.1-0.5
Incentive Sensitization - Breakpoint0.10.10.4-0.50.6-0.2-0.4-0.2-0.2-0.30.0-0.3-0.20.1-0.60.1-0.2
Sum of active levers in priming session hrs 5-60.10.00.10.3-0.20.20.20.30.30.3-0.10.30.20.00.20.10.0
Progressive ratio0.10.10.6-0.1-0.1-0.10.1-0.0-0.2-0.30.20.4-0.3-0.7-0.1-0.8-0.1
Food seeking constrained by brief footshock1.41.73.21.2-1.11.41.81.31.31.3-1.31.11.01.60.81.80.9
Seeking ratio, punishment vs. effort0.60.92.50.9-0.60.90.90.90.91.1-1.00.60.81.40.61.60.6
Retroperitoneal fat weight5.021.425.04.9-4.85.04.64.65.04.8-4.73.44.84.34.74.24.8
Reaction time number correct0.81.64.0-1.51.5-1.2-1.8-1.5-1.0-0.81.2-2.0-0.9-1.1-0.8-1.0-1.0
Reaction time mean minus median0.10.10.50.1-0.60.20.40.20.00.3-0.10.30.30.40.60.7-0.1
Reaction time mean minus median AUC0.41.12.10.8-1.41.01.30.90.80.9-0.90.61.01.01.51.30.7
Reaction time num false alarms0.10.10.3-0.30.0-0.3-0.1-0.4-0.4-0.40.5-0.3-0.3-0.50.0-0.4-0.6
Reaction time num false alarms AUC0.20.40.7-0.60.4-0.6-0.5-0.7-0.6-0.50.8-0.8-0.5-0.7-0.1-0.5-0.8
Reaction time trials correct on left0.81.64.0-1.51.5-1.2-1.8-1.5-1.0-0.81.2-2.0-0.9-1.1-0.8-1.0-1.0
Reaction time trials on left1.01.84.3-1.61.5-1.3-1.9-1.5-1.0-0.91.3-2.1-1.0-1.1-0.8-1.0-1.1
Reaction time mean0.10.10.4-0.2-0.0-0.3-0.3-0.3-0.4-0.30.6-0.0-0.4-0.20.0-0.1-0.4
Reaction time mean AUC0.00.10.3-0.20.0-0.2-0.3-0.3-0.4-0.30.5-0.1-0.3-0.20.1-0.1-0.3
Median of all reaction times0.20.20.7-0.30.3-0.4-0.5-0.4-0.6-0.50.8-0.2-0.6-0.5-0.2-0.4-0.5
Reaction time omissions0.30.51.0-0.90.7-0.8-0.8-0.8-0.7-0.60.8-0.9-0.7-0.3-0.2-0.1-1.0
Reaction time false alarm rate0.00.10.30.3-0.50.10.60.10.0-0.10.10.30.0-0.00.30.1-0.1
Reaction time premature initiation rate0.20.31.10.10.4-0.2-0.00.1-0.3-0.40.31.1-0.6-0.8-0.8-0.8-0.0
Reaction time premature initiations0.20.40.9-0.30.8-0.5-0.6-0.3-0.5-0.50.60.2-0.7-1.0-0.9-0.9-0.2
Std. dev. reaction times0.20.31.00.3-0.80.40.70.40.20.4-0.20.30.40.80.81.00.1
Reaction time trials completed1.01.84.3-1.61.5-1.3-1.9-1.5-1.0-0.91.3-2.1-1.0-1.1-0.8-1.0-1.1
Reaction time trials AUC0.71.33.1-1.31.3-1.1-1.6-1.3-0.8-0.71.1-1.8-0.8-1.0-0.7-0.9-0.8
Run reversals in cocaine runway, females0.60.60.9-0.61.0-0.8-0.8-0.8-0.6-0.90.9-1.0-0.4-0.6-0.7-0.7-0.9
Run reversals in cocaine runway, males0.70.72.20.50.10.80.30.70.90.6-0.8-0.11.31.11.51.30.5
Latency to leave start box in cocaine runway0.40.51.00.8-1.00.80.50.60.80.8-0.50.30.70.11.00.30.9
Latency to leave start box in cocaine runway, F0.00.00.3-0.1-0.0-0.0-0.4-0.1-0.1-0.10.1-0.2-0.1-0.6-0.0-0.3-0.0
Latency to leave start box in cocaine runway, M1.61.52.61.3-1.61.21.31.01.31.4-1.00.61.10.81.50.91.3
Std. dev. time between licks in bursts1.41.83.7-1.11.4-1.5-0.9-1.1-1.6-1.31.6-0.2-1.5-1.4-1.9-1.4-1.2
Total sessions with >9 infusions4.55.58.32.6-1.82.42.32.72.31.7-2.32.92.32.81.12.52.4
Short access day 1 total inactive lever presses0.91.26.41.1-1.10.61.11.30.50.4-0.72.50.61.4-0.51.40.1
Short access day 10 total inactive lever presses0.41.02.20.7-1.40.61.30.80.61.3-0.90.80.71.31.11.50.4
Short access day 1 total infusions1.11.43.71.2-1.11.01.31.40.70.6-1.01.90.91.8-0.11.60.8
Short access day 10 total infusions1.62.14.61.7-1.21.51.41.71.41.1-1.22.11.41.31.21.31.5
Short access total infusions2.43.17.62.0-1.21.61.72.11.51.1-1.52.71.62.20.52.01.6
Short access day 1 locomotion0.50.71.91.1-0.90.81.10.90.50.6-0.91.40.60.80.10.50.7
Short access day 10 total locomotion0.10.20.80.1-0.9-0.20.70.1-0.70.10.20.9-0.50.0-0.10.10.4
Short access total locomotion1.31.63.91.5-1.51.11.51.40.70.9-1.02.00.91.20.51.11.6
One hour access (0.3 mA shock)0.10.10.2-0.3-0.0-0.4-0.0-0.2-0.4-0.50.30.2-0.40.10.00.4-0.5
Compulsive drug intake0.40.51.2-0.90.9-0.8-1.0-0.7-0.5-0.90.3-1.1-0.2-0.1-0.90.1-0.5
One hour access (shock baseline)0.10.10.50.2-0.40.10.50.2-0.00.10.10.7-0.3-0.00.40.0-0.1
Social response proportion0.40.51.40.9-1.20.61.20.70.10.2-0.31.20.20.20.20.70.8
Social responses0.10.20.4-0.40.4-0.5-0.3-0.4-0.4-0.50.4-0.2-0.3-0.4-0.30.0-0.6
Social time1.82.53.3-1.61.5-1.7-1.4-1.6-1.7-1.51.8-1.0-1.8-1.6-1.7-1.4-1.6
Soleus weight0.20.62.1-0.81.1-0.7-1.0-0.5-0.5-0.90.5-0.4-0.4-0.5-1.5-0.4-0.6
Bone: stiffness1.62.76.81.9-1.61.61.62.01.41.6-1.32.61.31.41.01.61.3
Tibialis anterior weight0.62.13.5-1.41.4-1.6-1.4-1.3-1.5-1.41.6-0.7-1.5-1.4-1.9-1.5-1.3
Time to tail flick, vehicle, before self-admin0.00.00.20.0-0.00.0-0.10.10.1-0.10.00.4-0.0-0.20.0-0.1-0.2
Time to tail flick, vehicle, after self-admin1.01.42.4-1.31.3-1.2-1.0-1.2-1.2-1.01.1-1.0-1.3-1.1-0.9-0.9-1.5
Time to tail flick, test, before self-admin0.50.61.40.5-0.60.60.70.61.00.7-1.0-0.11.00.81.20.70.3
Time to tail flick, test, after self-admin0.30.30.7-0.60.8-0.6-0.2-0.6-0.5-0.80.6-0.7-0.4-0.4-0.3-0.3-0.6
Delta time to tail flick, vehicle, before/after SA0.00.00.2-0.0-0.00.10.40.1-0.20.0-0.00.3-0.10.2-0.20.3-0.2
Delta time to tail flick, test, before/after SA2.93.04.4-1.71.8-1.8-1.6-1.8-1.9-1.92.0-1.2-1.9-1.5-2.1-1.5-1.5
Tibia length0.82.13.31.3-0.91.60.91.61.71.6-1.51.41.81.61.11.61.3
Ambulatory time before self-admin0.30.40.8-0.60.9-0.8-0.3-0.7-0.9-0.90.7-0.4-0.8-0.2-0.7-0.1-0.4
Ambulatory time after self-admin1.41.73.5-1.21.5-1.4-1.0-1.1-1.5-1.41.4-0.3-1.3-0.9-1.9-1.1-1.3
Bone: tissue strength0.20.20.90.5-0.30.50.30.50.50.9-0.50.20.50.40.40.30.5
Total heroin consumption0.30.30.60.60.20.60.00.70.70.3-0.50.80.80.60.10.50.5
Bone: trabecular number0.00.00.3-0.10.00.00.0-0.10.00.6-0.0-0.40.00.10.10.00.1
Bone: trabecular spacing1.52.03.31.5-1.21.31.21.61.40.8-1.51.81.51.51.11.81.1
Bone: trabecular thickness0.20.31.0-0.40.2-0.3-0.1-0.5-0.6-0.20.7-0.3-0.7-0.6-0.5-1.0-0.4
Bone: trabecular tissue density1.92.74.3-1.31.2-1.6-1.2-1.4-1.9-2.01.9-0.5-1.9-2.1-1.9-1.9-1.6
Water consumed over 24 hours0.20.30.50.6-0.20.60.20.70.70.5-0.70.70.70.50.10.50.7
Number of responses in last shaping day0.60.61.8-0.20.6-0.5-0.2-0.1-1.0-1.00.91.3-0.7-0.7-1.3-0.8-0.4