Hub : Genes

Slc25a17

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Slc25a17 0.16 0.08 3.3e-16 0.07 0.11 0.12 0.1 1.2e-08 6.2e-12 1.3e-13 3.3e-11
2 pVTA gene expression Slc25a17 0.18 0.08 5.4e-08 0.17 0.17 0.16 0.07 6.4e-08 9.8e-08 1.3e-07 4.2e-04
3 OFC gene expression Slc25a17 0.44 0.14 7.4e-09 0.3 0.31 0.3 0.33 7.6e-08 4.9e-08 5.5e-08 9.8e-09
4 Adipose gene expression Slc25a17 0.22 0.09 0.0e+00 0.19 0.18 0.17 0.18 2.8e-20 2.0e-19 4.6e-19 1.2e-19
5 Brain gene expression Slc25a17 0.32 0.11 0.0e+00 0.39 0.41 0.41 0.42 1.8e-38 1.7e-40 2.3e-41 2.0e-41
6 BLA gene expression Slc25a17 0.48 0.15 0.0e+00 0.33 0.36 0.34 0.35 1.7e-18 7.4e-20 3.2e-19 2.0e-19
7 PL gene expression Slc25a17 0.29 0.11 0.0e+00 0.31 0.34 0.34 0.34 2.5e-34 1.2e-38 1.2e-38 7.3e-39
8 LHb gene expression Slc25a17 0.17 0.1 2.4e-03 0.13 0.08 0.08 0.08 5.3e-04 7.4e-03 5.4e-03 5.4e-03
9 IL gene expression Slc25a17 0.34 0.16 3.1e-05 0.13 0.12 0.13 0.15 4.9e-04 8.1e-04 5.9e-04 1.6e-04
10 Brain mRNA stability Slc25a17 0.04 0.02 7.8e-04 0.03 0.02 0.02 0.02 2.0e-03 5.4e-03 1.0e-02 6.4e-03
11 NAcc gene expression Slc25a17 0.16 0.07 0.0e+00 0.21 0.2 0.19 0.2 4.7e-24 1.8e-22 1.4e-21 3.0e-23
12 NAcc mRNA stability Slc25a17 0.03 0.02 2.5e-03 0.01 0.02 0.02 0.01 1.0e-02 2.2e-03 8.1e-04 6.8e-03
13 Adipose mRNA stability Slc25a17 0.03 0.02 2.4e-03 0 0.01 0 0 3.2e-01 1.1e-02 1.8e-01 1.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.20.30.30.3-0.60.2-0.6-0.3-0.40.5-0.5-0.30.60.00.1
Area under the delay curve0.50.51.30.61.1-0.80.8-0.7-0.7-0.90.3-0.5-0.90.70.1-0.3
BMI with tail1.85.78.2-2.0-2.62.1-2.92.22.42.5-2.52.22.8-2.12.32.3
BMI without tail0.10.31.3-0.4-0.7-0.1-1.10.10.30.4-0.30.10.70.10.50.6
Body weight2.18.810.7-2.9-3.23.1-3.32.93.13.1-2.93.02.8-2.92.62.7
Weight adjusted by age0.20.21.20.20.3-0.00.40.1-0.10.10.2-0.1-0.7-0.5-1.1-0.6
Bone surface0.10.30.50.50.7-0.50.6-0.6-0.5-0.60.4-0.3-0.70.5-0.1-0.2
Bone volume0.00.00.0-0.10.1-0.10.0-0.2-0.1-0.20.1-0.0-0.20.10.10.2
Breakpoint value in progressive ratio session0.10.10.30.20.0-0.50.1-0.20.0-0.10.1-0.30.30.30.50.5
Number of licking bursts1.21.42.41.51.5-1.11.1-1.1-1.3-1.20.7-0.9-1.30.9-1.5-1.2
Context. condit. distance diff. score6.07.210.3-3.2-3.23.2-2.82.92.32.6-2.83.02.8-3.00.91.0
Locomotion velocity, session 10.20.20.80.30.7-0.00.9-0.3-0.4-0.50.2-0.0-0.90.00.0-0.3
Locomotion distance, session 13.34.26.92.22.5-1.72.6-2.1-2.1-2.31.8-1.7-2.51.8-1.2-1.6
Locomotion velocity, session 20.20.20.6-0.4-0.40.4-0.40.40.50.5-0.30.50.6-0.40.70.6
Locomotion distance, session 22.83.96.62.62.3-2.12.3-2.1-1.7-2.01.9-2.0-2.22.1-0.2-0.6
Locomotion velocity, session 30.20.20.8-0.4-0.20.7-0.00.3-0.10.1-0.10.50.3-0.6-0.8-0.9
Locomotion distance, session 32.32.55.51.41.7-0.81.8-1.3-1.9-1.71.1-0.9-1.60.9-2.1-2.4
Stereotopy head waving bouts, day 31.31.52.5-1.3-1.21.1-1.11.21.41.3-1.01.01.2-1.11.61.5
Stereotopy head waving duration, day 34.25.16.1-2.5-2.32.0-2.22.22.52.4-1.91.92.4-2.02.42.4
Locomotion velocity, session 70.20.20.4-0.6-0.50.6-0.30.50.30.4-0.60.60.6-0.70.1-0.1
Locomotion distance, session 70.00.00.20.10.30.00.4-0.0-0.0-0.2-0.10.1-0.0-0.10.50.1
Stereotopy head waving bouts, day 72.22.44.0-2.0-1.81.7-1.61.71.41.5-1.71.61.6-1.70.70.8
Stereotopy head waving duration, day 71.92.33.9-2.0-1.91.6-1.71.61.31.5-1.51.41.7-1.50.30.6
Locomotion velocity, session 81.51.82.5-1.1-1.41.6-1.11.41.41.4-1.31.41.3-1.51.51.3
Locomotion distance, session 80.50.71.3-1.0-1.11.1-0.90.90.60.7-0.80.90.9-0.90.20.1
Degree of sensitization distance4.44.47.1-2.0-2.21.5-2.21.92.42.2-1.71.62.3-1.62.62.7
Degree of sensitization stereotypy1.21.32.4-1.5-1.41.4-1.11.20.91.0-1.41.31.0-1.3-0.00.1
Conditioned locomotion0.40.51.1-1.1-0.70.7-0.70.70.60.6-0.90.60.7-0.70.40.3
Cocaine response after cond. corrected0.10.10.4-0.6-0.20.2-0.20.30.40.3-0.00.20.4-0.30.50.4
Cocaine response after cond. not corrected0.10.10.2-0.5-0.2-0.0-0.20.10.20.10.2-0.00.4-0.10.30.3
Cocaine response before conditioning0.20.20.40.60.3-0.60.2-0.5-0.5-0.40.5-0.6-0.10.6-0.6-0.5
Saline control response0.20.31.1-0.20.2-0.40.1-0.4-0.7-0.50.2-0.20.00.4-1.0-1.0
Bone: connectivity density0.00.00.10.10.1-0.2-0.1-0.2-0.0-0.00.2-0.1-0.00.20.30.3
Bone: cortical apparent density1.11.52.51.31.4-0.91.2-1.0-1.4-1.20.8-1.0-1.30.9-1.6-1.6
Bone: cortical area1.82.83.6-1.6-1.61.6-1.61.61.81.7-1.61.61.4-1.61.91.9
Bone: cortical porosity1.11.22.2-1.5-1.50.9-1.10.91.21.1-0.50.61.2-0.81.11.3
Bone: cortical porosity2.42.63.8-1.9-1.91.4-1.61.41.81.7-1.01.11.8-1.31.81.9
Bone: cortical thickness0.30.51.0-0.3-0.60.7-0.70.60.70.8-0.80.70.6-0.71.01.0
Bone: cortical thickness0.40.41.3-0.1-0.30.6-0.40.50.60.6-0.80.60.3-0.61.21.0
Bone: cortical tissue density1.11.42.51.31.4-0.91.2-1.0-1.4-1.10.8-0.9-1.30.8-1.6-1.6
Condit. Reinf. active minus inactive responses0.20.20.80.90.7-0.40.5-0.4-0.4-0.40.4-0.3-0.50.4-0.2-0.2
Condit. Reinf. active-inactive response ratio0.10.10.3-0.2-0.10.4-0.40.40.20.4-0.60.60.4-0.6-0.1-0.1
Condit. Reinf. active responses1.51.92.91.71.5-1.61.2-1.5-1.3-1.41.4-1.4-1.11.6-0.9-0.9
Condit. Reinf. inactive responses3.03.65.71.91.9-2.31.7-2.0-1.9-2.01.9-2.1-1.52.4-1.3-1.3
Incentive salience index mean0.50.61.61.31.0-0.90.8-0.8-0.7-0.70.7-0.7-0.90.8-0.4-0.4
Condit. Reinf. lever presses0.81.01.81.31.1-1.30.9-1.0-0.8-0.91.0-1.1-1.01.2-0.5-0.4
Condit. Reinf. active minus inactive responses0.10.20.70.80.8-0.20.6-0.2-0.2-0.2-0.30.0-0.50.10.40.2
Condit. Reinf. active-inactive response ratio0.20.21.00.50.00.2-0.10.30.40.4-0.50.40.1-0.31.00.8
Condit. Reinf. active responses0.10.20.80.10.20.40.10.50.30.3-0.90.50.0-0.60.60.5
Condit. Reinf. inactive responses0.30.41.1-0.6-0.20.8-0.20.80.40.5-1.10.80.3-0.90.40.2
Condit. Reinf. lever presses0.40.52.01.40.8-0.90.7-0.7-0.5-0.50.7-0.6-0.60.7-0.2-0.2
Condit. Reinf. lever reinforcers received0.10.10.40.40.30.20.20.30.20.2-0.60.3-0.1-0.30.50.4
Conditioned reinforcement - actives0.20.20.8-0.30.30.20.40.1-0.4-0.1-0.90.30.2-0.40.6-0.5
Conditioned reinforcement - inactives0.50.50.90.90.9-0.90.6-0.8-0.8-0.8-0.1-0.7-0.70.90.30.1
Conditioned locomotion1.82.24.7-0.9-0.91.1-1.21.41.31.5-1.91.71.7-1.42.21.5
Patch foraging indifference point 0 sec0.30.51.41.20.4-0.80.4-0.8-0.4-0.51.0-1.2-0.61.0-0.00.2
Patch foraging indifference point AUC0.40.51.30.81.1-0.31.0-0.6-0.7-0.80.3-0.3-1.10.2-0.3-0.6
Delay disc. indifference point, 0s delay1.31.42.9-1.2-1.20.8-1.30.91.31.1-1.00.71.3-0.81.41.7
Delay disc. indifference point, 16s delay1.91.93.01.41.7-1.61.6-1.4-1.4-1.61.3-1.0-1.61.5-0.4-0.9
Delay disc. indifference point, 2s delay0.10.10.6-0.20.20.1-0.30.10.1-0.0-0.50.30.0-0.10.80.4
Delay disc. indifference point, 24s delay0.40.41.40.41.1-0.41.2-0.4-0.5-0.70.20.0-1.20.2-0.1-0.5
Delay disc. indifference point, 4s delay0.20.20.40.70.6-0.40.3-0.4-0.3-0.4-0.2-0.2-0.50.40.60.4
Delay disc. indifference point, 8s delay1.11.12.21.01.5-1.01.2-1.0-1.1-1.30.7-1.0-1.21.0-0.2-0.8
Indifference point function ln k1.31.83.3-1.3-1.81.3-1.51.41.31.5-1.21.31.7-1.20.50.7
Indifference point function log k1.31.83.3-1.3-1.81.3-1.51.41.31.5-1.21.31.7-1.20.50.7
Patch foraging total patch changes 0 sec0.40.71.71.30.5-0.90.5-0.9-0.5-0.61.0-1.3-0.71.1-0.10.1
Patch foraging total patch changes 12 sec0.00.00.20.40.00.0-0.0-0.20.0-0.00.2-0.2-0.30.10.30.4
Patch foraging total patch changes 18 sec0.20.30.60.80.3-0.30.5-0.5-0.1-0.30.2-0.7-0.60.50.80.8
Patch foraging total patch changes 24 sec0.40.50.80.60.8-0.80.7-0.7-0.6-0.80.6-0.8-0.80.9-0.1-0.2
Patch foraging total patch changes 6 sec0.50.71.71.30.9-0.80.7-0.9-0.4-0.70.9-0.9-1.00.90.70.6
Patch foraging time to switch 0 sec0.20.30.8-0.8-0.6-0.0-0.70.30.60.40.30.00.80.10.70.9
Patch foraging water rate 0 sec0.10.20.80.90.2-0.30.6-0.5-0.4-0.30.4-0.7-0.70.4-0.2-0.1
Patch foraging water rate 12 sec0.50.81.11.00.7-1.00.8-0.9-1.0-0.80.5-0.9-0.80.9-0.9-0.8
Patch foraging water rate 18 sec1.21.73.01.71.2-1.31.4-1.3-1.0-1.11.6-1.5-1.61.2-0.9-0.6
Patch foraging water rate 24 sec0.00.10.20.2-0.50.1-0.20.20.20.4-0.20.00.1-0.20.10.3
Patch foraging water rate 6 sec1.62.44.11.61.3-1.41.6-1.5-1.8-1.51.1-1.2-1.51.3-2.0-2.0
Seeking ratio, delayed vs. immediate footshock2.32.66.32.50.9-1.11.7-1.7-1.4-1.31.9-2.0-1.61.4-1.9-1.0
Distance traveled before self-admin0.10.10.40.40.1-0.4-0.1-0.1-0.1-0.1-0.2-0.1-0.60.20.10.3
Distance traveled after self-admin0.20.31.50.60.1-0.3-0.0-0.00.30.2-0.2-0.3-0.1-0.01.11.2
Extensor digitorum longus weight0.20.61.20.60.5-1.10.5-0.9-0.7-0.71.0-1.0-0.51.1-0.7-0.5
Bone: elastic displacement0.00.00.1-0.20.00.2-0.0-0.0-0.1-0.1-0.10.00.0-0.1-0.2-0.2
Bone: elastic work2.93.85.3-1.9-2.11.7-2.11.82.11.9-1.61.62.1-1.62.32.3
Bone: endosteal estimation0.71.52.5-1.6-1.31.1-1.11.11.31.1-1.01.01.2-1.01.51.5
Bone: endosteal perimeter1.73.65.9-2.4-2.01.8-1.91.92.01.9-1.81.81.9-1.81.61.7
Epididymis fat weight3.47.913.3-3.6-2.83.3-2.83.02.62.7-3.03.02.7-3.11.51.5
Delta time in closed arm before/after self-admin1.01.01.9-0.7-0.91.3-0.61.10.91.0-1.41.20.7-1.00.80.6
Delta time in open arm before/after self-admin0.40.41.00.20.8-1.00.3-0.7-0.7-0.70.5-0.90.10.7-0.1-0.4
Diff in mean of infusions in LGA sessions0.10.20.70.40.10.10.8-0.10.1-0.00.5-0.3-0.8-0.40.10.2
Delay discount exponential model param0.60.71.6-0.8-1.30.9-0.90.80.91.0-0.30.61.1-0.80.00.5
Extinction: sum of active levers before priming0.00.00.10.20.3-0.30.2-0.2-0.1-0.10.0-0.10.20.00.30.2
Active lever presses in extinction session 60.20.20.6-0.1-0.40.2-0.30.30.50.5-0.20.20.8-0.40.30.7
Bone: final force2.43.96.3-1.4-1.92.0-1.71.82.32.1-1.71.91.5-1.92.52.5
Bone: final moment2.54.16.9-1.4-1.92.0-1.71.92.32.1-1.81.91.5-2.02.62.6
Food consumed during 24 hour testing period2.42.94.0-1.2-1.71.7-1.71.61.91.7-1.41.81.6-1.62.02.0
Glucose0.20.30.80.60.1-0.80.1-0.6-0.3-0.30.7-0.9-0.20.90.00.2
Heart weight2.33.34.5-1.9-1.91.2-2.11.71.81.9-2.11.52.1-1.22.02.0
Delay discount hyperbolic model param0.40.41.2-0.6-1.10.7-0.70.60.70.9-0.10.40.8-0.7-0.30.3
Intermittent access intake day 1-15 change0.80.81.40.61.1-1.00.8-1.0-1.2-1.00.5-0.7-0.60.9-0.4-1.2
Intermittent access intake escalation0.80.81.30.51.1-1.10.9-1.0-1.1-1.00.6-0.9-0.71.0-0.3-1.1
Intermittent access intake escalation 20.40.40.60.20.6-0.80.7-0.7-0.7-0.70.4-0.8-0.40.7-0.1-0.6
Intermitt. access day 1 inactive lever presses0.40.41.6-0.0-0.70.3-0.80.50.70.7-0.70.20.2-0.40.81.3
Intermitt. access day 15 inactive lever presses0.20.31.20.50.10.1-0.60.30.20.3-1.10.7-0.0-0.30.60.6
Intermitt. access escalation Index0.10.10.70.90.2-0.3-0.0-0.0-0.10.1-0.1-0.3-0.60.2-0.40.1
Intermittent access day 1 total infusions0.80.91.9-0.8-0.80.9-0.81.00.90.9-1.40.80.4-0.81.21.2
Intermittent access day 15 total infusions0.10.20.60.10.5-0.50.3-0.3-0.4-0.4-0.3-0.3-0.30.40.70.1
Intermittent access terminal intake (last 3 days)0.10.10.3-0.40.3-0.20.2-0.0-0.1-0.2-0.40.0-0.00.10.5-0.1
Intermittent access total infusions0.40.41.4-0.6-0.40.3-0.40.50.60.5-0.80.50.3-0.41.21.0
Intermittent access day 1 locomotion0.70.71.7-0.5-0.80.6-0.60.70.80.8-1.00.60.8-0.61.31.2
Intermittent access day 15 total locomotion0.30.41.3-0.8-0.50.5-0.20.50.50.4-0.60.50.6-0.51.10.7
Intermittent access total locomotion0.91.02.9-0.9-0.90.8-0.70.91.00.9-1.00.90.8-0.81.71.4
Intermittent access standard deviation0.70.82.6-1.1-0.80.4-0.90.60.80.8-1.10.40.6-0.51.61.1
Left kidney weight11.532.540.1-5.7-5.56.2-5.76.15.75.8-6.26.35.4-6.14.44.3
Right kidney weight12.434.943.0-5.7-5.76.3-5.86.26.06.1-6.66.35.5-6.35.14.9
Cocaine induced anxiety2.22.54.4-1.6-1.81.4-1.51.72.11.9-0.81.41.5-1.41.21.8
Post-drug Anxiety0.70.71.5-0.6-0.90.6-0.90.81.21.1-0.30.70.7-0.70.91.2
Baseline Anxiety2.12.23.41.61.9-1.61.2-1.6-1.8-1.71.2-1.3-1.21.5-0.8-1.5
Tail length0.10.40.70.20.4-0.60.4-0.7-0.7-0.70.8-0.7-0.80.7-0.8-0.6
Length with tail0.41.42.4-1.4-1.31.5-1.11.21.21.1-1.01.40.6-1.30.60.8
Length without tail1.32.94.9-1.6-1.62.2-1.21.91.81.8-1.72.11.3-2.21.31.2
Times rat made contact with spout0.40.51.3-0.3-0.40.9-0.40.70.60.6-0.91.10.5-0.90.40.5
Lifetime Intake1.01.12.4-0.7-0.90.8-0.81.01.11.0-1.40.80.6-0.91.61.5
Liver weight, left0.71.22.8-1.7-1.21.4-1.21.10.80.9-1.21.20.9-1.2-0.00.1
Liver weight, right2.33.96.9-2.6-2.12.3-2.12.21.51.8-2.12.22.2-2.2-0.00.1
Locomotor activity1.93.14.5-2.1-1.61.5-2.11.71.71.7-1.82.02.1-1.61.51.3
Locomotor testing distance0.00.10.20.10.3-0.30.1-0.2-0.3-0.30.00.10.00.2-0.4-0.5
Locomotor testing rearing1.31.93.2-1.8-1.31.3-1.41.51.31.3-1.81.51.6-1.31.00.9
Locomotion in novel chamber2.73.36.61.42.0-2.01.2-1.7-2.6-2.10.7-1.6-0.52.2-1.7-2.6
Locomotion in novel chamber post-restriction0.70.91.20.70.8-0.81.0-1.0-1.1-1.01.0-0.8-1.00.7-1.1-1.1
Fecal boli incidents, locomotor time 10.20.30.60.40.6-0.70.5-0.4-0.1-0.40.8-0.3-0.50.60.50.5
Change in fecal boli incidents, locomotor task0.30.30.8-0.0-0.10.80.10.4-0.10.1-0.90.8-0.0-0.6-0.4-0.8
Time >=10cm from walls, locomotor time 10.40.41.0-0.3-0.80.6-0.30.70.90.8-0.20.40.4-0.70.51.0
Bouts of movement, locomotor time 10.90.92.2-0.9-1.21.5-0.51.11.11.1-0.61.00.6-1.40.10.6
Total resting periods, locomotor time 10.60.61.4-0.5-1.01.2-0.40.91.00.9-0.40.80.5-1.10.20.8
Rest time, locomotor task time 10.80.92.4-0.6-0.90.8-1.00.70.90.8-0.71.00.9-0.61.51.1
Distance moved, locomotor task time 10.20.21.1-1.0-0.50.4-0.20.60.40.5-0.60.20.5-0.5-0.0-0.1
Vertical activity count, locomotor time 10.00.00.1-0.1-0.0-0.10.30.00.10.10.1-0.3-0.00.1-0.00.2
Time >=10cm from walls, locomotor time 20.10.10.50.7-0.1-0.00.1-0.20.10.10.3-0.4-0.4-0.0-0.10.4
Bouts of movement, locomotor time 20.60.61.1-0.3-0.80.7-1.00.80.70.9-1.00.81.0-0.80.30.6
Total resting periods, locomotor time 20.40.50.7-0.1-0.60.6-0.80.70.60.8-0.80.70.8-0.70.40.7
Rest time, locomotor task time 20.10.10.30.40.6-0.30.3-0.4-0.4-0.50.30.0-0.50.30.4-0.3
Distance moved, locomotor task time 20.50.61.7-1.3-1.00.8-0.70.70.60.8-1.00.40.9-0.70.30.3
Vertical activity count, locomotor time 20.50.50.9-0.9-0.80.7-0.50.60.80.7-0.60.40.7-0.50.90.8
Light reinforcement 10.00.10.30.10.3-0.40.3-0.1-0.2-0.2-0.1-0.6-0.30.3-0.0-0.0
Light reinforcement 20.71.01.9-1.3-1.41.1-0.91.10.91.1-0.80.81.0-1.0-0.10.2
Bone: marrow area0.81.72.6-1.6-1.31.2-1.21.21.41.2-1.01.11.2-1.11.61.6
Bone: maximum diameter4.48.19.4-2.9-2.82.7-2.82.83.02.9-2.92.72.6-2.73.13.1
Bone: maximum force3.76.410.8-2.1-2.42.5-2.32.42.82.5-2.32.42.2-2.43.33.2
Bone: maximum moment4.06.911.6-2.2-2.42.5-2.42.42.92.6-2.42.52.3-2.53.43.3
Mean time between licks in bursts0.60.91.71.20.9-1.30.9-0.8-0.8-0.80.8-0.9-0.81.0-1.2-0.7
Mean num. licks in bursts2.42.83.6-1.9-1.81.9-1.41.71.71.7-1.61.91.7-1.81.51.3
Cd content in liver0.50.61.1-1.1-1.00.9-0.80.80.50.6-0.90.80.6-0.90.30.0
Co content in liver0.20.30.50.0-0.60.4-0.50.50.60.6-0.50.50.5-0.40.30.7
Cu content in liver3.74.56.02.12.0-2.32.1-2.3-2.0-2.22.4-2.5-2.22.4-1.3-1.3
Fe content in liver0.10.10.6-0.4-0.60.0-0.40.10.50.30.1-0.10.3-0.00.30.8
K content in liver0.70.71.51.20.7-0.90.8-0.9-0.7-0.70.9-0.9-0.90.8-0.5-0.3
Mg content in liver0.91.01.81.30.8-1.20.9-1.1-0.8-0.81.2-1.2-1.01.2-0.2-0.1
Mn content in liver0.10.10.5-0.1-0.00.40.10.2-0.3-0.0-0.30.3-0.1-0.5-0.5-0.7
Na content in liver2.52.63.71.61.5-1.91.6-1.8-1.5-1.71.8-1.9-1.61.9-1.1-1.0
Rb content in liver0.00.00.20.40.1-0.00.2-0.1-0.0-0.20.1-0.1-0.40.1-0.10.3
Se content in liver0.91.12.70.50.9-0.81.0-1.0-1.3-1.11.0-0.9-1.00.8-1.2-1.6
Sr content in liver1.11.01.90.71.1-1.01.1-1.0-1.2-1.00.9-1.0-0.90.9-0.9-1.4
Zn content in liver1.31.51.71.21.2-1.31.2-1.3-1.2-1.21.3-1.3-1.31.2-1.2-1.0
Bone: minimum diameter0.71.21.9-1.3-1.11.0-1.01.01.21.0-1.01.01.0-1.01.31.4
Time in familiar zone, hab. session 10.10.10.50.10.30.10.30.10.0-0.1-0.30.3-0.7-0.20.20.2
Time in novel zone, hab. session 10.80.82.3-1.1-1.10.6-1.30.70.80.9-0.50.51.5-0.50.50.6
Total zone transitions, hab. session 15.57.810.22.73.0-2.33.1-2.7-3.1-3.02.3-2.2-3.22.3-3.0-3.1
Total locomotion distance, hab. session 13.24.67.31.62.4-1.72.3-2.0-2.5-2.41.7-1.6-2.21.8-2.5-2.7
Locomotion velocity, hab. session 13.65.16.61.92.6-2.02.5-2.2-2.5-2.51.9-1.9-2.42.0-2.3-2.5
Time in familiar zone, hab. session 20.20.21.4-0.30.3-0.1-0.00.1-0.3-0.20.1-0.0-0.3-0.0-1.2-0.9
Time in novel zone, hab. session 20.20.21.30.2-0.30.10.00.00.30.2-0.10.10.3-0.01.10.8
Total zone transitions, hab. session 21.62.14.21.91.7-1.31.8-1.5-1.3-1.51.2-1.3-2.01.3-0.5-0.6
Total locomotion distance, hab. session 21.11.52.11.51.4-1.41.3-1.3-1.1-1.31.2-1.3-1.31.4-0.3-0.4
Locomotion velocity, hab. session 21.92.53.41.81.8-1.81.7-1.7-1.5-1.71.5-1.7-1.81.8-0.5-0.6
Novel to familiar place preference ratio2.32.43.3-1.8-1.61.7-1.71.51.41.5-1.61.81.8-1.60.90.8
Novelty place preference3.13.24.5-2.1-1.82.0-2.01.91.61.7-1.92.12.0-1.90.90.7
Time in novel zone, NPP test3.94.05.6-2.3-2.02.3-2.22.11.81.9-2.12.42.2-2.21.10.9
Total zone transitions, NPP test5.07.19.92.73.1-2.33.1-2.5-2.9-2.82.2-2.1-3.12.3-2.5-2.7
Total locomotion distance, NPP test2.23.04.71.92.2-1.61.9-1.8-1.8-1.81.6-1.5-1.81.6-1.3-1.5
Locomotion velocity, NPP test3.14.46.22.12.5-2.02.2-2.1-2.2-2.21.9-1.9-2.22.0-1.7-1.9
Intraocular pressure0.30.41.1-0.8-0.51.0-0.50.70.40.6-0.90.50.4-1.00.30.0
Delta distance traveled before/after self-admin0.20.20.7-0.3-0.30.50.00.40.40.4-0.40.30.4-0.70.80.6
Delta ambulatory time before/after self-admin0.20.31.1-0.1-0.20.40.10.40.50.5-0.40.20.3-0.61.00.9
Parametrial fat weight0.10.30.6-0.4-0.50.6-0.70.50.50.6-0.50.50.7-0.50.40.3
Pavlov. Cond. lever latency0.91.12.0-1.4-1.11.3-1.01.11.00.9-1.11.21.0-1.10.80.6
Pavlov. Cond. magazine entry latency0.60.81.71.30.9-0.91.0-0.8-0.6-0.71.0-0.9-1.20.8-0.3-0.2
Pavlov. Cond. change in total contacts1.21.33.41.81.4-1.41.2-1.2-0.9-1.01.0-1.2-1.21.20.0-0.0
Pavlov. Cond. index score0.20.31.01.00.6-0.60.6-0.5-0.3-0.30.5-0.6-0.70.5-0.00.1
Pavlov. Cond. latency score0.20.30.90.90.5-0.70.5-0.5-0.3-0.30.5-0.6-0.60.5-0.10.0
Pavlov. Cond. lever contacts1.11.32.21.51.1-1.41.1-1.2-1.0-1.01.1-1.3-1.11.2-0.7-0.5
Pavlov. Cond. magazine entry number0.40.51.2-1.1-0.90.7-0.80.60.60.6-0.60.61.0-0.50.50.4
Pavlov. Cond. intertrial magazine entries1.01.32.01.41.4-1.41.1-1.2-1.0-1.11.0-1.1-1.01.4-0.2-0.3
Pavlov. Cond. lever-magazine prob. diff.0.40.51.31.20.8-0.80.8-0.7-0.5-0.50.6-0.7-0.90.6-0.4-0.2
Pavlov. Cond. response bias0.50.71.61.30.9-0.90.9-0.8-0.6-0.60.8-0.8-1.00.8-0.3-0.2
Pavlov. Cond. lever latency1.01.33.6-1.9-0.91.5-0.81.30.80.8-1.41.30.8-1.40.40.1
Pavlov. Cond. magazine entry latency2.63.07.12.71.5-1.91.7-1.9-1.3-1.52.1-1.9-1.82.0-0.4-0.2
Pavlov. Cond. change in total contacts0.60.83.61.90.4-1.00.4-0.60.20.10.8-0.7-0.40.71.11.3
Pavlov. Cond. index score1.92.46.72.61.4-1.81.4-1.7-1.1-1.21.9-1.7-1.51.7-0.5-0.3
Pavlov. Cond. latency score2.42.98.02.81.5-2.01.6-1.9-1.3-1.42.1-1.8-1.71.9-0.6-0.3
Pavlov. Cond. lever contacts0.81.23.51.90.8-1.50.7-1.2-0.7-0.71.4-1.2-0.61.3-0.4-0.1
Pavlov. Cond. magazine entry number1.21.54.4-2.1-1.01.3-1.21.30.81.0-1.51.31.4-1.30.30.1
Pavlov. Cond. intertrial magazine entries2.32.94.3-2.0-1.31.7-1.61.81.61.8-2.11.91.8-1.81.61.3
Pavlov. Cond. lever-magazine prob. diff.1.92.46.22.51.3-1.81.4-1.7-1.1-1.21.9-1.7-1.41.8-0.5-0.3
Pavlov. Cond. response bias0.81.14.02.00.8-1.40.7-1.2-0.6-0.61.3-1.2-0.81.30.00.2
Time in closed arm before self-admin3.33.77.92.11.3-2.21.8-2.2-1.2-1.72.8-2.7-1.92.3-0.10.2
Time in closed arm after self-admin0.80.82.2-0.8-1.10.8-0.70.71.00.9-0.50.50.7-0.61.51.4
Time in open arm before self-admin0.20.20.9-0.7-0.20.4-0.10.4-0.00.1-0.20.40.0-0.4-0.8-1.0
Time in open arm after self-admin0.40.41.2-0.10.7-0.80.3-0.5-0.8-0.60.5-0.50.30.6-0.9-1.1
Bone: periosteal estimation1.73.54.8-2.1-1.91.8-1.81.72.01.8-1.61.71.7-1.72.22.2
Bone: periosteal perimeter4.16.89.4-3.1-2.72.5-2.72.62.72.6-2.52.52.4-2.52.42.5
Bone: post-yield work0.40.52.6-0.1-0.10.4-0.40.40.80.5-0.60.60.3-0.41.61.4
Progressive ratio test 1 active lever presses0.60.61.7-0.8-0.50.6-0.30.80.90.8-0.90.70.2-0.81.31.2
Progressive ratio test 1 breakpoint0.40.40.9-0.8-0.30.4-0.20.70.70.6-0.80.50.2-0.60.90.7
Progressive ratio test 1 inactive lever presses0.40.41.5-0.3-0.60.0-0.60.50.70.5-0.90.30.6-0.11.01.2
Progressive ratio test 2 active lever presses0.10.10.60.30.5-0.10.7-0.1-0.3-0.3-0.2-0.1-0.7-0.10.2-0.1
Progressive ratio test 2 breakpoint0.10.10.40.10.20.10.40.10.10.1-0.40.2-0.4-0.40.60.3
Progressive ratio test 2 inactive lever presses0.50.61.10.91.0-0.91.0-0.8-0.9-0.90.1-0.7-1.10.7-0.1-0.2
Incentive Sensitization - Responses0.60.71.01.01.0-0.80.8-0.8-0.9-0.80.3-0.6-1.00.6-0.7-1.0
Incentive Sensitization - Breakpoint0.40.40.70.80.8-0.50.6-0.5-0.7-0.60.1-0.4-0.70.4-0.5-0.8
Sum of active levers in priming session hrs 5-60.00.00.3-0.20.2-0.50.0-0.00.1-0.00.2-0.20.10.1-0.10.2
Progressive ratio0.10.10.30.20.3-0.6-0.0-0.3-0.1-0.20.5-0.3-0.00.30.30.3
Food seeking constrained by brief footshock1.21.53.4-1.4-0.60.9-1.71.21.01.2-1.81.31.1-1.31.21.0
Seeking ratio, punishment vs. effort0.50.61.8-0.8-0.50.8-0.80.80.60.8-1.40.90.5-0.80.80.5
Retroperitoneal fat weight4.715.420.5-4.5-4.04.3-4.04.34.04.1-3.84.23.7-4.42.42.6
Reaction time number correct1.52.14.50.81.2-0.81.8-1.2-1.6-1.51.1-1.3-1.60.9-2.1-2.0
Reaction time mean minus median0.10.10.3-0.4-0.2-0.2-0.30.20.20.1-0.30.20.50.00.10.2
Reaction time mean minus median AUC0.60.81.8-1.1-1.00.6-1.21.00.80.8-0.91.01.3-0.70.40.5
Reaction time num false alarms0.10.10.30.00.1-0.30.1-0.3-0.3-0.40.5-0.6-0.00.4-0.3-0.3
Reaction time num false alarms AUC0.30.40.70.20.4-0.60.5-0.6-0.7-0.70.6-0.8-0.40.6-0.8-0.8
Reaction time trials correct on left1.52.14.50.81.2-0.81.8-1.2-1.6-1.51.1-1.3-1.60.9-2.1-2.0
Reaction time trials on left1.62.34.90.91.3-0.81.9-1.3-1.7-1.61.2-1.4-1.71.0-2.2-2.1
Reaction time mean0.10.10.30.20.1-0.60.4-0.3-0.2-0.20.3-0.6-0.20.5-0.3-0.1
Reaction time mean AUC0.10.10.30.20.2-0.50.4-0.2-0.2-0.30.2-0.5-0.20.5-0.4-0.2
Median of all reaction times0.20.30.60.30.4-0.80.7-0.5-0.4-0.40.5-0.8-0.50.7-0.5-0.2
Reaction time omissions0.60.81.20.70.8-0.81.0-0.8-1.0-1.00.6-1.0-0.90.8-1.1-1.0
Reaction time false alarm rate0.10.10.3-0.2-0.3-0.1-0.50.20.20.2-0.0-0.10.50.00.30.3
Reaction time premature initiation rate0.20.31.30.6-0.1-0.50.0-0.30.50.10.8-0.2-0.20.51.01.1
Reaction time premature initiations0.20.30.90.70.3-0.60.7-0.6-0.1-0.41.0-0.6-0.80.60.10.2
Std. dev. reaction times0.20.20.6-0.6-0.50.2-0.50.50.40.4-0.70.40.8-0.20.30.3
Reaction time trials completed1.62.34.90.91.3-0.81.9-1.3-1.7-1.61.2-1.4-1.71.0-2.2-2.1
Reaction time trials AUC1.11.63.60.71.0-0.61.6-1.1-1.4-1.31.0-1.2-1.50.7-1.9-1.8
Run reversals in cocaine runway, females1.31.22.90.81.2-1.01.0-0.8-1.1-1.00.8-1.0-1.30.9-1.7-1.3
Run reversals in cocaine runway, males0.40.41.3-0.8-0.21.0-0.00.70.20.4-0.90.70.2-1.20.1-0.3
Latency to leave start box in cocaine runway0.60.61.4-1.0-1.10.9-0.80.80.80.8-0.30.61.2-0.70.30.3
Latency to leave start box in cocaine runway, F0.10.10.50.4-0.0-0.10.4-0.3-0.3-0.30.7-0.4-0.10.3-0.5-0.4
Latency to leave start box in cocaine runway, M3.33.16.1-2.4-1.71.6-1.91.81.71.7-1.41.72.5-1.41.51.0
Std. dev. time between licks in bursts1.51.83.41.91.5-1.81.5-1.3-1.0-1.11.4-1.4-1.41.5-0.5-0.1
Total sessions with >9 infusions1.82.03.4-1.0-1.31.4-1.01.41.51.5-1.81.41.0-1.51.61.7
Short access day 1 total inactive lever presses0.91.03.4-0.3-0.10.2-0.80.60.80.6-1.40.81.1-0.31.81.7
Short access day 10 total inactive lever presses0.20.20.9-0.5-0.10.1-0.70.40.20.3-0.90.40.4-0.10.40.4
Short access day 1 total infusions1.01.03.2-0.4-0.90.8-1.11.00.91.0-1.80.90.7-0.80.91.3
Short access day 10 total infusions2.12.44.0-1.4-1.91.6-1.11.51.91.6-1.11.11.1-1.52.02.0
Short access total infusions2.83.15.3-1.1-1.81.7-1.61.82.01.9-2.11.41.2-1.61.92.3
Short access day 1 locomotion0.20.20.70.1-0.2-0.1-0.50.30.50.5-0.60.40.2-0.20.50.8
Short access day 10 total locomotion0.20.20.70.0-0.3-0.4-0.6-0.10.10.2-0.4-0.20.70.30.90.6
Short access total locomotion1.92.03.3-0.8-1.51.1-1.41.31.51.6-1.61.11.4-1.21.71.8
One hour access (0.3 mA shock)0.40.50.90.50.8-0.80.8-0.8-0.9-0.90.2-0.9-0.60.7-0.0-0.6
Compulsive drug intake3.13.14.52.02.0-1.32.1-1.7-2.0-1.81.5-1.7-1.91.2-1.4-1.9
One hour access (shock baseline)0.30.30.9-0.9-0.60.2-0.60.40.60.5-0.60.30.6-0.30.70.6
Social response proportion0.60.61.6-0.4-1.00.1-1.10.50.90.8-0.10.11.1-0.01.21.3
Social responses0.10.10.30.40.5-0.40.2-0.4-0.4-0.50.5-0.4-0.30.40.0-0.2
Social time1.92.53.81.91.7-2.01.5-1.8-1.5-1.71.6-1.6-1.51.9-0.8-0.9
Soleus weight0.31.02.11.41.3-0.81.2-1.0-1.0-1.00.6-0.7-1.30.8-0.5-0.6
Bone: stiffness2.74.28.1-1.8-2.01.8-1.91.82.32.0-1.71.71.8-1.72.92.8
Tibialis anterior weight0.51.72.51.51.3-1.61.4-1.5-1.1-1.21.5-1.5-1.31.5-0.5-0.5
Time to tail flick, vehicle, before self-admin0.00.00.1-0.3-0.00.10.2-0.00.1-0.20.20.1-0.30.10.00.1
Time to tail flick, vehicle, after self-admin0.91.01.80.60.7-0.60.8-1.1-1.1-1.21.3-0.7-0.71.1-1.3-1.1
Time to tail flick, test, before self-admin0.10.10.4-0.50.30.10.00.1-0.1-0.3-0.10.3-0.3-0.0-0.6-0.4
Time to tail flick, test, after self-admin1.31.31.91.31.3-1.40.9-1.2-1.2-1.21.1-1.2-0.71.3-1.1-0.9
Delta time to tail flick, vehicle, before/after SA0.10.10.20.40.1-0.3-0.3-0.3-0.2-0.20.3-0.20.40.4-0.3-0.1
Delta time to tail flick, test, before/after SA3.12.84.72.21.5-1.71.5-1.8-1.7-1.51.7-1.9-1.41.7-1.6-1.2
Tibia length0.72.03.2-1.3-1.21.8-1.11.51.51.3-1.61.71.0-1.61.51.4
Ambulatory time before self-admin0.40.41.11.00.7-0.80.2-0.5-0.8-0.6-0.2-0.4-1.00.6-0.5-0.4
Ambulatory time after self-admin0.80.92.61.61.1-1.10.9-1.0-0.9-0.90.6-1.1-1.10.9-0.00.0
Bone: tissue strength0.10.10.2-0.3-0.30.4-0.30.40.40.5-0.40.40.2-0.40.20.3
Total heroin consumption0.10.10.30.4-0.10.20.40.30.40.4-0.10.2-0.0-0.50.40.5
Bone: trabecular number0.10.10.4-0.6-0.20.3-0.30.20.00.1-0.20.40.2-0.3-0.4-0.4
Bone: trabecular spacing1.31.74.2-0.8-0.91.1-1.01.21.41.2-1.31.31.0-1.22.01.8
Bone: trabecular thickness0.10.10.5-0.1-0.0-0.40.0-0.4-0.3-0.30.5-0.4-0.10.5-0.7-0.4
Bone: trabecular tissue density1.11.63.11.50.9-1.61.2-1.4-0.8-1.01.7-1.8-1.01.6-0.4-0.2
Water consumed over 24 hours0.50.61.3-0.5-0.61.1-0.80.70.70.7-0.81.10.7-0.90.70.7
Number of responses in last shaping day0.70.71.31.10.3-0.80.7-0.8-0.2-0.60.8-1.1-0.90.81.11.0