Hub : Genes

Skap1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC alternative TSS NM_173311.2 0.43 0.19 1.1e-03 0.05 0.06 0.1 0.05 3.0e-03 1.5e-03 7.1e-05 3.6e-03
2 OFC gene expression Skap1 0.21 0.16 1.1e-03 0.09 0.08 0.06 0.09 4.5e-03 6.2e-03 1.4e-02 4.0e-03
3 IL gene expression Skap1 0.18 0.14 3.1e-03 0.1 0.06 0.08 0.08 1.8e-03 1.8e-02 4.7e-03 6.5e-03
4 Brain alternative TSS XM_039085326.2 0.06 0.07 4.4e-04 0.04 0.03 0.04 0.04 5.3e-05 3.8e-04 1.3e-04 1.1e-04
5 Brain alternative TSS XM_039085326.2 0.02 0.02 8.0e-03 0.03 0.02 0.03 0.02 1.8e-03 4.2e-03 2.0e-03 2.4e-03
6 PL alternative TSS XM_039085326.2 0.15 0.1 2.3e-13 0.11 0.1 0.11 0.11 8.2e-12 2.0e-11 6.2e-12 1.3e-11
7 PL gene expression Skap1 0.21 0.11 0.0e+00 0.2 0.21 0.21 0.21 1.2e-21 9.3e-23 3.3e-22 2.9e-22
8 PL alternative TSS XM_039085326.2 0.09 0.06 5.4e-12 0.1 0.11 0.1 0.1 3.6e-11 8.2e-12 3.0e-11 3.4e-11
9 BLA alternative TSS XM_063268504.1 0.07 0.06 2.8e-04 0.04 0.06 0.06 0.05 3.6e-03 6.0e-04 7.2e-04 1.7e-03
10 Brain gene expression Skap1 0.07 0.05 4.6e-09 0.08 0.1 0.09 0.09 2.8e-08 2.9e-09 7.3e-09 7.0e-09
11 IC alternative TSS XM_039085326.2 0.24 0.18 7.4e-06 0.08 0.1 0.09 0.09 3.2e-04 5.0e-05 1.1e-04 9.9e-05
12 IC alternative TSS XM_039085326.2 0.43 0.18 1.3e-07 0.13 0.15 0.16 0.17 6.3e-06 7.6e-07 4.5e-07 1.6e-07
13 IC gene expression Skap1 0.5 0.13 1.2e-14 0.29 0.28 0.29 0.3 1.8e-12 3.1e-12 1.8e-12 5.9e-13
14 BLA alternative TSS XM_039085326.2 0.14 0.08 1.4e-09 0.12 0.16 0.14 0.14 5.9e-07 8.4e-09 4.8e-08 6.7e-08
15 BLA gene expression Skap1 0.21 0.09 8.7e-15 0.2 0.26 0.25 0.26 8.2e-11 3.7e-14 2.5e-13 5.7e-14
16 PL alternative TSS NM_173311.2 0.6 0.08 7.4e-08 0.05 0.06 0.04 0.05 3.3e-06 1.2e-06 6.3e-05 2.0e-06
17 NAcc gene expression Skap1 0.06 0.03 2.1e-13 0.07 0.09 0.09 0.09 2.2e-10 4.1e-13 5.8e-13 7.9e-13
18 NAcc intron excision ratio chr10_81949106_81989761 0.04 0.04 1.0e-04 0.03 0.02 0.02 0.03 4.1e-05 3.3e-04 1.4e-04 7.5e-05
19 NAcc alternative TSS XM_039085326.2 0.02 0.02 1.6e-04 0.02 0.02 0.02 0.02 1.2e-03 4.3e-04 1.3e-03 1.5e-03
20 BLA alternative TSS XM_039085326.2 0.11 0.06 3.5e-07 0.09 0.12 0.12 0.11 1.6e-05 1.1e-06 7.1e-07 1.9e-06
21 NAcc alternative TSS XM_039085326.2 0.03 0.02 4.4e-05 0.02 0.02 0.02 0.02 3.6e-04 1.1e-04 2.0e-04 3.3e-04
22 NAcc intron excision ratio chr10_81983757_81989761 0.04 0.04 1.9e-03 0.02 0.01 0.01 0.01 1.1e-03 3.3e-03 1.0e-02 3.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.73.03.41.71.71.3-1.7-1.7-1.71.7-1.71.71.8-1.8-1.71.7-1.81.81.81.8-1.8-1.8-1.8-1.81.6
Area under the delay curve0.40.52.2-1.5-0.2-1.00.00.10.7-0.60.6-0.5-0.50.70.8-0.90.5-0.5-0.9-0.60.90.60.60.7-0.7
BMI with tail19.968.679.78.68.88.8-8.6-8.3-8.98.6-8.58.58.3-8.5-8.68.5-8.18.18.08.1-7.7-7.9-7.8-7.87.0
BMI without tail1.54.46.12.12.42.3-2.5-2.4-2.32.2-2.22.22.1-2.1-2.32.2-2.02.01.92.0-1.6-1.9-2.0-1.81.5
Body weight1.35.86.82.42.52.0-2.3-2.1-2.52.5-2.52.52.4-2.5-2.62.6-2.52.42.22.4-2.4-2.4-2.4-2.42.2
Weight adjusted by age0.40.61.6-1.2-0.5-0.70.20.20.7-0.70.7-0.7-0.70.80.6-0.70.8-0.8-0.6-0.81.20.80.70.8-0.8
Bone surface0.71.22.61.61.10.8-1.1-1.0-1.21.1-1.11.11.0-1.2-1.21.2-1.01.01.41.0-1.0-1.0-1.0-1.00.8
Bone volume1.73.03.81.81.61.3-1.6-1.5-1.71.7-1.71.71.7-1.8-1.91.9-1.81.72.01.8-1.6-1.7-1.7-1.81.6
Breakpoint value in progressive ratio session2.42.94.4-0.3-1.8-1.51.61.81.6-1.71.8-1.9-1.91.61.4-1.41.9-1.9-1.2-1.91.82.01.71.9-2.1
Number of licking bursts0.20.41.2-0.1-1.0-0.81.11.10.6-0.60.6-0.6-0.60.40.3-0.30.5-0.5-0.3-0.50.30.40.50.4-0.3
Context. condit. distance diff. score0.60.71.61.11.01.0-1.3-1.1-0.90.9-0.90.90.8-0.8-0.90.8-0.70.70.80.7-0.6-0.7-0.6-0.60.5
Locomotion velocity, session 10.10.10.5-0.3-0.10.00.10.1-0.20.2-0.20.20.3-0.3-0.10.2-0.40.40.30.4-0.5-0.4-0.5-0.50.7
Locomotion distance, session 13.84.76.5-2.5-2.3-2.52.42.52.3-2.22.2-2.2-2.22.22.1-2.22.0-2.0-2.3-2.02.02.01.91.9-1.6
Locomotion velocity, session 21.41.63.3-1.8-1.2-1.41.31.11.3-1.31.2-1.2-1.21.31.3-1.31.2-1.2-1.2-1.21.41.11.11.1-1.0
Locomotion distance, session 24.86.79.3-2.5-2.9-3.12.93.02.8-2.72.7-2.7-2.62.62.5-2.52.5-2.5-2.4-2.52.22.42.32.3-2.0
Locomotion velocity, session 30.10.10.4-0.10.60.2-0.6-0.4-0.30.2-0.20.20.2-0.1-0.20.2-0.20.20.00.20.2-0.1-0.1-0.0-0.0
Locomotion distance, session 32.42.63.9-1.7-1.2-1.61.11.21.5-1.61.6-1.5-1.61.71.6-1.61.6-1.6-1.8-1.62.01.71.81.7-1.7
Stereotopy head waving bouts, day 34.85.66.82.62.32.6-2.0-1.8-2.42.4-2.42.42.3-2.5-2.42.5-2.42.42.42.4-2.6-2.4-2.3-2.42.3
Stereotopy head waving duration, day 33.74.45.62.02.12.4-2.0-1.7-2.12.1-2.12.12.1-2.1-2.02.1-2.12.12.12.1-2.3-2.1-2.2-2.12.1
Locomotion velocity, session 71.21.31.9-0.2-1.1-1.21.31.41.0-1.11.1-1.2-1.21.10.8-1.01.3-1.3-1.1-1.21.21.21.31.2-1.3
Locomotion distance, session 75.67.18.9-1.6-2.7-2.82.83.02.7-2.72.7-2.7-2.82.62.5-2.52.7-2.7-2.6-2.72.52.72.72.7-2.6
Stereotopy head waving bouts, day 70.30.30.40.10.60.6-0.5-0.4-0.60.6-0.60.60.6-0.6-0.60.6-0.60.60.60.6-0.5-0.6-0.7-0.60.6
Stereotopy head waving duration, day 70.20.30.5-0.00.70.6-0.5-0.5-0.50.5-0.50.50.5-0.5-0.50.5-0.50.50.50.6-0.4-0.6-0.6-0.60.6
Locomotion velocity, session 80.30.42.01.40.60.5-0.9-0.8-0.70.6-0.60.50.5-0.6-0.80.7-0.40.40.90.4-0.3-0.4-0.3-0.40.2
Locomotion distance, session 80.71.01.2-1.0-0.9-1.10.70.81.1-1.01.0-1.0-1.01.11.0-1.01.0-1.0-1.0-1.01.01.01.01.0-1.0
Degree of sensitization distance0.10.10.60.8-0.4-0.10.50.50.1-0.10.2-0.2-0.30.0-0.10.00.2-0.20.1-0.2-0.10.20.10.2-0.2
Degree of sensitization stereotypy0.10.10.5-0.7-0.4-0.40.50.40.4-0.30.3-0.4-0.40.30.3-0.30.3-0.3-0.2-0.30.50.30.30.3-0.2
Conditioned locomotion1.41.72.91.11.41.4-1.6-1.7-1.31.3-1.31.31.3-1.2-1.21.2-1.31.31.21.3-1.2-1.2-1.3-1.21.1
Cocaine response after cond. corrected5.76.97.52.22.62.7-2.6-2.7-2.72.7-2.72.72.7-2.7-2.62.7-2.62.62.72.7-2.4-2.6-2.6-2.62.5
Cocaine response after cond. not corrected3.03.64.31.52.02.0-2.1-2.0-2.01.9-1.91.91.9-1.9-1.81.8-1.91.91.91.9-1.6-1.9-1.8-1.91.8
Cocaine response before conditioning3.03.53.9-1.5-1.8-1.91.71.92.0-2.02.0-1.9-1.91.92.0-2.01.9-1.9-1.9-1.91.71.91.91.9-1.8
Saline control response0.20.31.10.4-0.10.10.00.10.2-0.40.4-0.4-0.40.50.4-0.50.6-0.6-0.6-0.60.60.70.70.7-1.1
Bone: connectivity density0.20.40.80.90.90.3-0.8-0.8-0.60.5-0.60.60.6-0.6-0.50.5-0.60.60.70.6-0.6-0.5-0.5-0.50.3
Bone: cortical apparent density5.98.010.6-1.2-2.6-2.82.72.72.7-2.82.9-2.9-3.02.92.5-2.63.1-3.1-2.8-3.12.83.13.23.1-3.2
Bone: cortical area0.30.41.20.51.10.8-1.0-1.0-0.80.6-0.70.70.6-0.6-0.70.5-0.60.60.50.5-0.1-0.5-0.5-0.40.1
Bone: cortical porosity0.20.30.5-0.70.60.6-0.5-0.5-0.40.4-0.50.50.6-0.4-0.10.2-0.60.6-0.00.6-0.4-0.6-0.7-0.60.7
Bone: cortical porosity0.40.40.7-0.60.80.8-0.6-0.6-0.60.6-0.70.70.7-0.6-0.40.4-0.80.80.10.7-0.4-0.8-0.8-0.70.8
Bone: cortical thickness0.10.21.00.70.40.2-0.4-0.4-0.2-0.10.1-0.1-0.20.20.1-0.20.4-0.4-0.3-0.40.50.50.60.5-1.0
Bone: cortical thickness1.11.32.6-1.6-0.7-1.20.60.61.3-1.21.1-1.0-1.01.21.5-1.51.0-1.0-1.3-1.01.01.11.01.1-1.1
Bone: cortical tissue density6.58.811.3-1.4-2.8-2.92.82.92.9-3.03.0-3.1-3.13.02.6-2.83.2-3.2-2.9-3.22.93.23.43.2-3.4
Condit. Reinf. active minus inactive responses0.50.61.9-0.2-1.3-0.71.41.20.7-0.70.8-0.8-0.80.60.6-0.60.7-0.7-0.4-0.70.50.70.70.6-0.6
Condit. Reinf. active-inactive response ratio0.10.10.2-0.2-0.10.40.1-0.1-0.30.3-0.20.20.3-0.3-0.10.1-0.30.30.20.3-0.4-0.3-0.4-0.30.4
Condit. Reinf. active responses0.60.72.4-0.2-1.4-1.01.51.40.9-0.80.9-0.9-0.80.70.7-0.70.7-0.7-0.5-0.70.40.60.70.6-0.5
Condit. Reinf. inactive responses0.60.81.5-0.5-0.9-1.21.11.21.1-0.90.9-0.9-0.90.90.9-0.80.8-0.8-0.9-0.80.60.70.90.7-0.6
Incentive salience index mean1.11.43.2-1.1-1.8-1.21.81.61.2-1.11.2-1.2-1.21.01.0-1.01.1-1.1-0.8-1.10.91.00.90.9-0.7
Condit. Reinf. lever presses1.62.23.8-1.6-1.9-1.71.91.81.6-1.51.5-1.5-1.51.41.3-1.31.4-1.4-1.2-1.41.31.31.21.3-1.0
Condit. Reinf. active minus inactive responses0.00.10.7-0.8-0.0-0.20.30.20.2-0.10.1-0.00.00.00.1-0.1-0.10.1-0.20.1-0.1-0.2-0.2-0.20.4
Condit. Reinf. active-inactive response ratio0.10.10.6-0.2-0.1-0.00.30.1-0.10.2-0.20.20.2-0.3-0.10.2-0.40.40.20.4-0.6-0.4-0.5-0.50.8
Condit. Reinf. active responses0.10.11.3-1.20.1-0.20.10.10.2-0.30.2-0.1-0.10.30.4-0.40.1-0.1-0.6-0.10.30.10.10.10.0
Condit. Reinf. inactive responses0.20.20.6-0.70.1-0.2-0.1-0.00.3-0.40.4-0.3-0.40.50.5-0.60.5-0.5-0.7-0.50.80.50.60.6-0.7
Condit. Reinf. lever presses0.91.24.9-2.2-0.4-0.90.40.41.1-1.11.0-0.9-0.81.21.4-1.40.9-0.8-1.7-0.91.20.90.91.0-0.8
Condit. Reinf. lever reinforcers received0.20.21.3-1.20.0-0.40.20.20.4-0.40.4-0.3-0.30.50.5-0.60.3-0.3-0.8-0.30.60.30.30.4-0.3
Conditioned reinforcement - actives0.20.31.8-1.3-0.5-0.61.01.10.4-0.20.2-0.00.00.00.4-0.2-0.30.3-0.40.3-0.3-0.4-0.6-0.51.0
Conditioned reinforcement - inactives0.00.00.40.10.40.30.10.2-0.20.00.0-0.0-0.1-0.1-0.10.00.1-0.1-0.1-0.10.30.20.00.2-0.6
Conditioned locomotion1.41.96.2-1.60.70.7-0.5-0.3-0.81.0-1.21.31.4-1.1-0.60.8-1.71.70.51.7-1.4-1.8-2.1-1.92.5
Patch foraging indifference point 0 sec0.71.32.7-0.41.20.9-1.6-1.7-1.01.1-1.21.21.2-1.0-0.70.8-1.21.21.21.2-0.7-1.2-1.4-1.21.2
Patch foraging indifference point AUC0.10.20.4-0.6-0.2-0.00.20.20.3-0.40.4-0.4-0.40.50.5-0.50.4-0.4-0.6-0.40.40.40.60.5-0.4
Delay disc. indifference point, 0s delay0.70.71.6-0.5-0.1-0.60.10.10.7-0.80.8-0.7-0.80.91.1-1.10.9-0.9-1.0-0.91.11.01.11.1-1.3
Delay disc. indifference point, 16s delay0.40.51.2-0.11.00.2-1.1-1.0-0.60.6-0.70.80.8-0.5-0.30.4-0.80.80.40.8-0.8-0.7-0.7-0.60.6
Delay disc. indifference point, 2s delay0.20.21.3-1.1-0.2-0.70.10.10.4-0.40.4-0.3-0.30.40.3-0.40.4-0.4-0.4-0.40.70.40.40.4-0.5
Delay disc. indifference point, 24s delay0.50.62.3-1.5-0.7-0.90.60.70.7-0.70.7-0.7-0.70.70.9-0.90.6-0.6-0.9-0.61.00.60.60.6-0.5
Delay disc. indifference point, 4s delay3.13.34.9-1.8-1.2-1.91.11.11.8-1.81.8-1.7-1.81.91.8-1.91.8-1.8-2.0-1.92.21.91.92.0-2.1
Delay disc. indifference point, 8s delay0.20.32.0-1.4-0.2-0.80.10.30.6-0.50.4-0.3-0.30.50.6-0.70.3-0.3-0.7-0.30.50.30.30.3-0.2
Indifference point function ln k0.00.10.3-0.4-0.3-0.50.20.20.3-0.20.2-0.1-0.10.20.2-0.20.1-0.1-0.2-0.00.40.00.10.00.2
Indifference point function log k0.00.10.3-0.4-0.3-0.50.20.20.3-0.20.2-0.1-0.10.20.2-0.20.1-0.1-0.2-0.00.40.00.10.00.2
Patch foraging total patch changes 0 sec0.71.42.9-0.31.31.0-1.6-1.7-1.11.1-1.21.21.3-1.1-0.80.9-1.21.31.11.2-0.6-1.2-1.4-1.21.1
Patch foraging total patch changes 12 sec0.10.12.1-1.50.1-0.0-0.2-0.10.0-0.0-0.10.10.20.10.4-0.3-0.20.2-0.30.20.2-0.2-0.1-0.20.3
Patch foraging total patch changes 18 sec1.01.52.9-0.51.51.4-1.7-1.6-1.21.1-1.31.31.4-1.0-0.70.8-1.41.40.81.4-1.0-1.3-1.3-1.31.3
Patch foraging total patch changes 24 sec0.50.91.9-1.00.80.9-1.1-1.1-0.80.9-0.90.91.0-0.9-0.60.7-1.11.11.01.0-0.7-1.0-1.4-1.01.1
Patch foraging total patch changes 6 sec0.50.71.3-1.10.90.8-1.1-1.1-0.70.8-0.90.91.0-0.6-0.40.5-0.90.90.30.9-0.4-0.9-0.8-0.91.0
Patch foraging time to switch 0 sec0.00.00.1-0.0-0.3-0.30.20.20.1-0.10.1-0.1-0.0-0.00.10.0-0.10.10.30.1-0.4-0.1-0.2-0.10.2
Patch foraging water rate 0 sec0.91.82.41.11.51.5-1.5-1.5-1.41.5-1.51.51.5-1.4-1.41.3-1.41.41.01.4-0.9-1.3-1.4-1.31.1
Patch foraging water rate 12 sec0.10.10.60.20.60.6-0.8-0.5-0.40.3-0.30.30.2-0.1-0.40.2-0.10.1-0.20.10.50.00.20.1-0.3
Patch foraging water rate 18 sec0.10.21.0-0.2-0.30.0-0.00.00.1-0.20.3-0.3-0.40.30.1-0.20.5-0.5-0.3-0.51.00.50.40.6-0.9
Patch foraging water rate 24 sec0.91.22.30.91.01.5-1.3-1.3-1.21.2-1.21.21.1-1.1-1.11.0-1.11.10.91.1-0.7-1.0-1.1-1.00.8
Patch foraging water rate 6 sec0.00.00.10.40.1-0.2-0.10.10.1-0.00.1-0.1-0.10.0-0.10.00.1-0.10.0-0.10.20.20.00.2-0.3
Seeking ratio, delayed vs. immediate footshock1.61.95.52.41.91.8-1.7-1.9-1.61.4-1.41.41.3-1.2-1.41.3-1.11.11.01.1-0.8-1.0-0.8-0.90.2
Distance traveled before self-admin0.60.72.4-1.5-1.1-0.91.01.21.0-0.90.8-0.8-0.70.81.1-0.90.6-0.6-0.9-0.60.70.50.50.4-0.1
Distance traveled after self-admin0.30.43.6-1.90.3-0.2-0.2-0.1-0.00.2-0.30.50.5-0.20.2-0.0-0.60.6-0.30.6-0.1-0.7-0.5-0.71.1
Extensor digitorum longus weight0.41.73.71.01.91.7-1.8-1.8-1.61.4-1.41.41.3-1.2-1.51.3-1.11.10.81.2-0.4-1.1-0.9-1.00.7
Bone: elastic displacement0.10.20.50.10.10.1-0.2-0.2-0.20.3-0.30.40.4-0.4-0.30.4-0.50.50.30.5-0.6-0.5-0.7-0.50.6
Bone: elastic work0.00.00.1-0.40.2-0.1-0.2-0.1-0.0-0.0-0.00.10.10.00.0-0.1-0.10.2-0.30.1-0.1-0.1-0.1-0.10.2
Bone: endosteal estimation0.20.51.0-0.60.50.4-0.6-0.5-0.50.6-0.60.70.7-0.6-0.60.6-0.80.80.60.8-0.3-0.8-1.0-0.91.0
Bone: endosteal perimeter0.61.21.90.10.90.9-0.9-1.0-1.01.1-1.11.11.1-1.1-1.11.1-1.21.21.41.2-0.8-1.2-1.4-1.21.4
Epididymis fat weight0.20.71.40.31.11.2-0.6-0.4-0.90.8-0.80.90.9-0.8-0.80.7-0.90.9-0.00.9-0.8-0.9-0.7-0.91.0
Delta time in closed arm before/after self-admin0.20.20.80.40.70.9-0.4-0.6-0.60.5-0.50.40.3-0.4-0.50.4-0.20.20.10.30.5-0.30.1-0.20.1
Delta time in open arm before/after self-admin1.51.52.2-1.2-1.2-1.30.91.01.3-1.31.3-1.3-1.31.31.0-1.11.3-1.3-0.8-1.31.21.31.31.4-1.5
Diff in mean of infusions in LGA sessions0.70.92.11.1-1.3-0.71.31.40.7-0.80.9-1.0-1.00.50.4-0.41.0-1.00.0-1.00.71.00.90.9-1.1
Delay discount exponential model param0.60.72.91.70.31.1-0.2-0.3-0.80.8-0.70.60.6-0.9-0.91.0-0.70.71.00.7-1.1-0.7-0.7-0.80.8
Extinction: sum of active levers before priming0.80.92.3-1.5-0.9-0.80.81.01.0-1.01.0-0.9-0.91.00.9-0.90.9-0.9-1.0-0.91.00.90.60.8-0.9
Active lever presses in extinction session 60.10.10.20.00.20.3-0.3-0.3-0.20.2-0.20.20.2-0.2-0.10.2-0.30.30.40.3-0.5-0.3-0.5-0.30.2
Bone: final force0.20.40.70.10.80.8-0.5-0.6-0.70.6-0.60.70.7-0.6-0.50.5-0.70.70.30.7-0.3-0.7-0.5-0.70.5
Bone: final moment0.30.50.90.20.90.8-0.7-0.7-0.70.7-0.70.70.7-0.6-0.60.6-0.70.80.40.7-0.4-0.7-0.6-0.70.6
Food consumed during 24 hour testing period1.72.33.1-1.6-1.8-1.71.71.71.5-1.51.5-1.5-1.51.51.3-1.41.5-1.5-1.4-1.51.71.41.51.4-1.3
Glucose1.82.93.92.01.52.0-1.6-1.7-1.81.8-1.71.71.7-1.7-1.71.8-1.61.61.71.6-1.8-1.6-1.5-1.61.6
Heart weight1.72.74.01.51.41.9-1.2-1.2-1.81.7-1.71.61.6-1.8-2.01.9-1.61.61.91.6-1.5-1.6-1.6-1.61.5
Delay discount hyperbolic model param0.60.72.71.60.31.1-0.1-0.2-0.80.7-0.70.60.6-0.8-0.90.9-0.70.61.00.7-1.1-0.7-0.7-0.80.8
Intermittent access intake day 1-15 change0.20.31.7-0.9-0.4-0.70.10.20.30.1-0.10.20.3-0.20.20.0-0.60.60.40.6-1.0-0.6-0.8-0.71.3
Intermittent access intake escalation0.10.21.2-0.5-0.3-0.6-0.00.10.30.1-0.10.20.3-0.20.20.1-0.50.50.40.5-0.9-0.6-0.7-0.61.1
Intermittent access intake escalation 21.01.14.50.70.30.2-0.7-0.5-0.50.8-0.80.91.0-0.9-0.40.7-1.21.21.11.2-2.1-1.2-1.4-1.31.7
Intermitt. access day 1 inactive lever presses0.00.10.60.80.00.10.20.2-0.1-0.10.1-0.2-0.20.00.00.00.3-0.30.0-0.30.10.40.50.4-0.6
Intermitt. access day 15 inactive lever presses0.91.72.91.61.41.5-1.4-1.4-1.31.3-1.21.21.3-1.3-0.91.1-1.31.31.61.2-1.7-1.1-1.5-1.11.0
Intermitt. access escalation Index0.30.43.7-1.9-1.1-0.70.90.90.5-0.40.3-0.3-0.20.30.5-0.40.1-0.1-0.10.00.3-0.2-0.1-0.20.7
Intermittent access day 1 total infusions0.00.10.5-0.20.10.20.20.2-0.0-0.10.1-0.1-0.10.10.1-0.10.2-0.2-0.6-0.20.70.20.40.2-0.4
Intermittent access day 15 total infusions0.00.00.3-0.5-0.3-0.30.20.40.3-0.20.1-0.1-0.10.10.3-0.2-0.00.0-0.30.00.1-0.1-0.0-0.10.2
Intermittent access terminal intake (last 3 days)0.10.10.30.30.10.2-0.10.0-0.20.2-0.30.30.3-0.3-0.10.2-0.40.40.10.4-0.6-0.4-0.4-0.50.6
Intermittent access total infusions0.00.00.10.20.30.3-0.1-0.1-0.20.2-0.20.20.2-0.1-0.10.2-0.20.2-0.20.20.2-0.2-0.1-0.20.0
Intermittent access day 1 locomotion0.10.20.6-0.5-0.6-0.20.70.80.4-0.40.4-0.4-0.40.40.4-0.40.3-0.3-0.5-0.40.60.30.20.3-0.3
Intermittent access day 15 total locomotion0.10.10.9-0.9-0.5-0.40.40.60.3-0.10.1-0.00.00.00.3-0.1-0.20.2-0.20.2-0.1-0.2-0.4-0.30.6
Intermittent access total locomotion0.10.20.7-0.8-0.2-0.10.20.30.10.1-0.10.20.3-0.20.10.0-0.40.5-0.00.4-0.4-0.5-0.7-0.50.9
Intermittent access standard deviation0.81.63.91.11.10.8-1.2-1.0-0.81.1-1.11.21.3-1.2-0.71.0-1.51.51.31.3-2.0-1.3-1.7-1.31.5
Left kidney weight0.00.10.10.20.3-0.3-0.2-0.2-0.20.2-0.20.20.2-0.3-0.40.3-0.20.20.40.2-0.0-0.2-0.2-0.20.1
Right kidney weight0.41.82.51.21.31.0-1.4-1.2-1.41.4-1.41.41.4-1.4-1.61.5-1.41.41.51.4-1.1-1.4-1.4-1.41.3
Cocaine induced anxiety0.30.42.31.50.50.6-0.2-0.2-0.60.6-0.50.50.5-0.6-0.50.6-0.50.50.70.5-0.7-0.5-0.5-0.50.4
Post-drug Anxiety0.20.20.70.5-0.5-0.40.80.80.5-0.40.5-0.4-0.40.30.5-0.40.3-0.3-0.4-0.3-0.30.30.30.2-0.3
Baseline Anxiety1.01.21.5-1.0-1.2-1.21.11.11.2-1.21.2-1.2-1.11.11.2-1.11.0-1.0-1.1-1.10.51.10.91.0-0.9
Tail length19.074.298.2-9.9-9.0-9.78.88.69.4-8.98.8-8.7-8.68.88.9-8.98.2-8.2-8.6-8.28.08.17.78.0-6.9
Length with tail7.030.645.0-6.0-5.8-6.75.85.76.1-5.85.7-5.6-5.55.65.6-5.65.3-5.2-5.5-5.35.05.25.05.1-4.4
Length without tail0.20.61.10.91.00.3-0.7-0.5-0.80.8-0.80.90.8-0.8-1.00.9-0.80.80.50.8-0.7-0.8-0.6-0.80.8
Times rat made contact with spout0.20.31.2-0.1-1.1-0.51.01.00.4-0.40.5-0.5-0.50.30.3-0.30.4-0.5-0.3-0.40.40.40.40.3-0.3
Lifetime Intake0.00.00.1-0.00.10.2-0.1-0.1-0.10.1-0.10.10.1-0.1-0.10.1-0.10.1-0.10.10.3-0.1-0.1-0.1-0.0
Liver weight, left0.00.10.30.20.20.5-0.0-0.1-0.50.2-0.20.10.0-0.2-0.40.20.1-0.10.1-0.00.40.10.20.1-0.2
Liver weight, right0.10.20.5-0.5-0.2-0.40.40.30.4-0.40.4-0.3-0.30.40.4-0.40.3-0.3-0.7-0.30.50.30.50.3-0.4
Locomotor activity0.20.40.80.40.60.2-0.5-0.2-0.50.6-0.60.60.6-0.7-0.40.5-0.80.80.60.7-0.6-0.7-0.9-0.70.7
Locomotor testing distance0.81.52.21.11.30.9-1.2-1.0-1.11.2-1.21.21.2-1.3-1.01.1-1.31.31.31.3-1.2-1.3-1.5-1.31.2
Locomotor testing rearing0.00.10.60.80.6-0.2-0.5-0.5-0.10.1-0.10.20.1-0.20.00.1-0.20.20.30.1-0.2-0.0-0.30.0-0.3
Locomotion in novel chamber0.20.30.90.9-0.3-0.10.20.50.1-0.30.4-0.5-0.50.3-0.1-0.10.7-0.7-0.2-0.60.80.71.00.7-0.7
Locomotion in novel chamber post-restriction1.52.54.21.01.82.1-1.9-1.6-1.91.7-1.71.71.6-1.6-1.71.6-1.51.51.11.6-1.0-1.5-1.2-1.51.5
Fecal boli incidents, locomotor time 13.24.77.32.71.72.1-1.9-2.1-2.12.2-2.12.02.1-2.2-2.32.3-2.12.02.72.1-2.5-2.0-2.1-2.01.9
Change in fecal boli incidents, locomotor task2.32.23.0-1.1-1.3-1.31.41.71.3-1.51.5-1.5-1.61.51.2-1.31.6-1.6-1.7-1.61.61.61.71.5-1.7
Time >=10cm from walls, locomotor time 10.20.30.7-0.3-0.0-0.20.10.10.4-0.50.4-0.4-0.50.50.5-0.60.5-0.5-0.8-0.50.80.60.60.6-0.7
Bouts of movement, locomotor time 10.10.10.30.50.50.4-0.6-0.3-0.30.3-0.30.30.3-0.3-0.30.3-0.30.30.40.2-0.3-0.2-0.3-0.1-0.0
Total resting periods, locomotor time 10.40.51.31.10.90.8-0.9-0.6-0.70.7-0.70.60.6-0.7-0.70.7-0.60.60.70.5-0.7-0.5-0.5-0.50.2
Rest time, locomotor task time 10.30.40.90.80.40.8-0.4-0.4-0.50.6-0.60.60.6-0.7-0.60.7-0.60.60.80.6-0.9-0.6-0.7-0.60.7
Distance moved, locomotor task time 11.11.62.1-0.9-1.5-1.31.51.41.2-1.31.3-1.3-1.31.31.3-1.31.3-1.3-1.3-1.31.21.31.31.2-1.2
Vertical activity count, locomotor time 10.20.61.9-1.4-0.6-0.50.60.70.5-0.70.7-0.6-0.70.80.8-0.80.7-0.7-1.2-0.71.00.60.70.6-0.5
Time >=10cm from walls, locomotor time 20.40.61.4-0.8-0.6-0.60.60.60.6-0.70.7-0.8-0.80.80.8-0.80.9-0.9-1.0-0.81.20.80.90.8-0.9
Bouts of movement, locomotor time 20.00.10.20.30.2-0.1-0.2-0.4-0.20.2-0.20.20.2-0.3-0.10.3-0.30.20.40.2-0.3-0.2-0.3-0.20.2
Total resting periods, locomotor time 20.10.10.20.50.3-0.1-0.3-0.4-0.20.3-0.30.30.3-0.3-0.30.4-0.30.30.50.3-0.4-0.3-0.3-0.30.2
Rest time, locomotor task time 20.70.92.00.6-1.0-0.41.00.90.9-0.80.9-1.0-1.00.80.6-0.71.1-1.1-0.6-1.10.81.11.21.1-1.4
Distance moved, locomotor task time 20.20.21.5-1.2-0.3-0.70.30.40.3-0.40.4-0.3-0.30.50.5-0.50.3-0.3-0.7-0.30.70.30.30.3-0.1
Vertical activity count, locomotor time 20.20.23.2-1.8-0.0-0.40.10.20.1-0.10.00.00.00.20.2-0.2-0.10.1-0.70.10.5-0.1-0.2-0.20.7
Light reinforcement 10.10.20.70.40.40.0-0.4-0.3-0.30.4-0.40.40.4-0.5-0.40.5-0.50.50.70.5-0.8-0.5-0.7-0.60.7
Light reinforcement 20.10.10.4-0.6-0.5-0.40.60.40.4-0.20.2-0.3-0.20.20.0-0.10.1-0.10.1-0.10.10.00.0-0.00.2
Bone: marrow area0.20.30.8-0.80.40.3-0.5-0.4-0.40.5-0.50.60.6-0.5-0.40.4-0.70.70.50.7-0.1-0.7-0.9-0.70.9
Bone: maximum diameter0.61.11.60.21.01.0-1.0-1.0-1.11.1-1.11.11.1-1.1-1.01.0-1.21.11.31.1-0.6-1.1-1.2-1.11.1
Bone: maximum force0.61.01.80.41.31.2-1.2-1.0-1.11.0-1.11.11.1-1.0-0.90.9-1.11.10.71.1-0.6-1.1-0.9-1.00.9
Bone: maximum moment0.71.32.20.51.51.3-1.3-1.2-1.21.1-1.21.21.2-1.1-1.11.0-1.21.20.81.2-0.7-1.2-1.0-1.11.0
Mean time between licks in bursts0.40.92.11.01.51.4-1.4-1.4-1.20.9-1.01.00.9-0.8-1.10.9-0.70.70.60.7-0.4-0.7-0.5-0.60.3
Mean num. licks in bursts0.00.00.10.10.10.3-0.2-0.2-0.10.0-0.00.00.00.00.1-0.10.1-0.1-0.1-0.10.20.10.10.1-0.2
Cd content in liver0.00.00.10.3-0.00.2-0.10.0-0.20.1-0.10.00.0-0.1-0.20.20.0-0.00.10.0-0.0-0.00.0-0.00.0
Co content in liver0.00.00.70.80.0-0.00.20.1-0.00.0-0.0-0.0-0.0-0.0-0.00.10.0-0.0-0.1-0.0-0.50.0-0.00.0-0.0
Cu content in liver5.36.311.7-2.3-3.0-2.83.23.42.6-2.52.6-2.6-2.52.32.4-2.32.4-2.4-2.2-2.42.42.22.32.1-1.9
Fe content in liver0.50.60.8-0.2-0.8-0.70.90.80.8-0.80.8-0.8-0.80.80.9-0.80.8-0.8-0.8-0.80.90.80.80.8-0.8
K content in liver0.20.21.3-0.5-0.9-0.50.91.20.5-0.40.4-0.4-0.40.20.3-0.20.2-0.2-0.2-0.30.00.20.00.10.1
Mg content in liver3.73.86.6-1.7-2.3-2.12.42.62.0-1.92.0-2.0-2.01.81.7-1.71.9-1.9-1.8-1.91.91.81.81.7-1.6
Mn content in liver5.46.07.5-2.3-2.5-2.72.52.32.6-2.62.5-2.5-2.52.52.6-2.62.4-2.4-2.2-2.42.12.42.32.4-2.2
Na content in liver0.40.52.0-0.1-0.30.10.40.3-0.20.5-0.40.40.5-0.7-0.50.6-0.80.80.90.7-1.0-0.9-1.0-1.01.4
Rb content in liver0.60.61.3-0.7-0.6-0.81.01.20.8-0.80.8-0.8-0.80.70.6-0.70.8-0.8-1.0-0.80.80.80.80.7-0.7
Se content in liver0.50.52.01.40.40.6-0.4-0.5-0.80.7-0.70.60.6-0.8-0.90.8-0.60.61.00.6-0.9-0.6-0.6-0.70.6
Sr content in liver2.01.72.9-1.7-1.3-1.50.80.81.4-1.41.3-1.3-1.31.41.5-1.51.3-1.3-1.2-1.31.31.31.21.3-1.2
Zn content in liver0.10.10.3-0.1-0.3-0.00.40.6-0.10.2-0.10.10.1-0.3-0.30.3-0.20.20.20.2-0.2-0.3-0.3-0.30.4
Bone: minimum diameter0.10.10.3-0.20.60.3-0.3-0.3-0.30.3-0.30.40.4-0.3-0.30.2-0.40.40.10.40.1-0.3-0.4-0.30.3
Time in familiar zone, hab. session 10.30.31.10.7-0.2-0.20.00.20.3-0.50.5-0.5-0.60.50.4-0.40.6-0.7-0.4-0.70.50.70.80.7-1.0
Time in novel zone, hab. session 12.72.73.41.41.41.3-1.3-1.2-1.51.6-1.61.61.6-1.7-1.71.7-1.71.71.91.7-1.8-1.7-1.8-1.81.8
Total zone transitions, hab. session 16.38.810.0-1.7-3.1-3.02.93.22.9-3.03.1-3.1-3.23.02.7-2.83.1-3.1-2.8-3.12.73.13.13.1-3.2
Total locomotion distance, hab. session 13.24.56.1-1.2-2.3-2.32.32.52.2-2.22.2-2.2-2.22.11.9-2.02.2-2.2-1.9-2.21.92.12.22.1-2.0
Locomotion velocity, hab. session 14.25.97.5-2.0-2.6-2.52.62.72.4-2.52.5-2.5-2.52.42.3-2.32.5-2.5-2.3-2.52.22.42.42.4-2.3
Time in familiar zone, hab. session 20.90.93.01.71.11.2-1.2-1.1-1.11.0-0.90.90.9-0.9-1.01.0-0.80.81.00.8-0.9-0.7-0.6-0.70.5
Time in novel zone, hab. session 20.10.10.5-0.7-0.3-0.50.30.30.4-0.30.3-0.3-0.30.30.3-0.30.2-0.2-0.4-0.20.30.20.20.2-0.2
Total zone transitions, hab. session 23.14.05.3-2.1-2.3-2.32.32.32.1-2.12.1-2.1-2.02.01.9-1.91.9-1.9-1.9-1.91.81.81.81.8-1.5
Total locomotion distance, hab. session 20.30.41.4-0.8-0.9-1.01.11.20.7-0.70.7-0.7-0.60.50.5-0.50.5-0.5-0.6-0.50.30.40.40.4-0.1
Locomotion velocity, hab. session 20.50.71.7-1.0-1.1-1.11.21.30.9-0.80.8-0.8-0.80.70.7-0.70.6-0.6-0.7-0.60.40.50.60.5-0.2
Novel to familiar place preference ratio0.30.40.70.1-0.3-0.50.30.30.5-0.60.6-0.6-0.70.60.5-0.50.7-0.7-0.5-0.70.60.70.70.8-0.9
Novelty place preference0.40.41.00.1-0.3-0.50.20.20.6-0.70.6-0.7-0.70.70.6-0.60.8-0.8-0.6-0.80.70.80.80.8-1.0
Time in novel zone, NPP test0.30.30.80.4-0.1-0.30.10.10.4-0.50.5-0.5-0.60.50.4-0.40.6-0.6-0.5-0.60.60.70.70.7-0.9
Total zone transitions, NPP test5.27.510.0-3.2-2.9-3.12.82.82.9-2.82.8-2.8-2.72.82.8-2.82.6-2.6-2.7-2.62.62.62.62.5-2.2
Total locomotion distance, NPP test1.52.03.1-1.7-1.5-1.81.51.61.5-1.51.5-1.4-1.41.41.4-1.41.3-1.3-1.4-1.31.31.31.31.2-1.0
Locomotion velocity, NPP test2.13.04.2-2.0-1.8-2.01.81.81.8-1.81.8-1.7-1.71.81.8-1.81.6-1.6-1.8-1.61.61.61.61.6-1.3
Intraocular pressure1.42.13.4-1.8-1.1-1.21.31.01.5-1.51.5-1.4-1.31.61.8-1.71.3-1.3-1.8-1.31.51.31.41.3-1.1
Delta distance traveled before/after self-admin0.70.71.4-0.61.20.5-1.1-1.2-0.80.8-1.01.01.0-0.7-0.70.7-0.90.90.41.0-0.4-0.9-0.6-0.91.0
Delta ambulatory time before/after self-admin0.91.21.80.31.30.9-1.1-1.2-1.21.2-1.21.21.2-1.1-1.21.1-1.11.10.71.2-0.8-1.1-0.8-1.11.1
Parametrial fat weight0.10.20.5-0.30.70.4-0.6-0.4-0.60.5-0.50.60.5-0.5-0.60.5-0.50.50.30.5-0.1-0.5-0.4-0.50.5
Pavlov. Cond. lever latency1.31.62.51.21.31.3-1.3-1.2-1.21.2-1.31.31.3-1.3-1.01.1-1.31.41.11.3-1.6-1.3-1.3-1.31.4
Pavlov. Cond. magazine entry latency0.10.21.5-1.2-0.3-0.30.50.40.4-0.30.3-0.3-0.20.30.4-0.40.2-0.1-0.4-0.20.40.20.00.2-0.0
Pavlov. Cond. change in total contacts3.03.24.0-1.7-1.9-1.92.02.01.8-1.81.8-1.9-1.81.81.7-1.71.8-1.8-1.7-1.81.81.71.71.7-1.7
Pavlov. Cond. index score0.81.02.1-1.5-1.0-1.01.11.01.0-1.01.0-1.0-1.01.00.9-1.00.9-0.9-1.0-0.91.10.90.80.9-0.9
Pavlov. Cond. latency score0.81.01.8-1.3-1.1-1.01.11.11.0-1.01.0-1.0-1.01.00.9-1.01.0-1.0-1.0-1.01.11.00.91.0-0.9
Pavlov. Cond. lever contacts2.52.93.7-1.8-1.9-1.71.81.71.7-1.71.7-1.8-1.81.71.5-1.61.7-1.7-1.6-1.71.91.71.61.7-1.6
Pavlov. Cond. magazine entry number0.50.72.61.60.80.8-0.9-0.9-0.80.8-0.80.80.7-0.8-0.90.9-0.70.70.90.7-0.9-0.7-0.5-0.70.5
Pavlov. Cond. intertrial magazine entries0.60.71.30.8-1.0-0.91.01.20.7-0.80.8-0.9-0.90.60.5-0.50.9-0.9-0.5-0.90.60.81.10.8-0.9
Pavlov. Cond. lever-magazine prob. diff.0.81.02.6-1.6-1.0-1.01.11.01.0-1.01.0-1.0-1.01.01.0-1.00.9-0.9-1.1-0.91.20.90.80.9-0.9
Pavlov. Cond. response bias1.01.22.6-1.6-1.0-1.11.11.11.1-1.11.1-1.1-1.01.11.1-1.21.0-1.0-1.2-1.01.31.00.91.0-0.9
Pavlov. Cond. lever latency0.81.12.2-0.5-1.4-1.11.41.51.0-1.01.1-1.1-1.10.90.8-0.81.1-1.1-0.8-1.11.11.01.00.9-0.9
Pavlov. Cond. magazine entry latency0.30.30.7-0.2-0.8-0.50.80.60.6-0.60.6-0.6-0.60.60.6-0.50.6-0.6-0.4-0.60.20.50.50.5-0.5
Pavlov. Cond. change in total contacts0.20.30.9-0.90.70.3-0.8-0.9-0.20.3-0.40.50.6-0.20.0-0.0-0.50.6-0.00.5-0.4-0.5-0.5-0.40.6
Pavlov. Cond. index score0.20.30.5-0.20.60.5-0.6-0.7-0.40.4-0.50.60.6-0.4-0.20.3-0.60.60.30.6-0.7-0.6-0.6-0.60.7
Pavlov. Cond. latency score0.10.10.3-0.40.20.2-0.3-0.4-0.10.2-0.20.30.3-0.10.00.1-0.30.40.10.3-0.5-0.3-0.4-0.30.5
Pavlov. Cond. lever contacts0.70.92.00.51.31.0-1.3-1.4-0.90.9-1.01.01.0-0.8-0.80.8-1.01.00.71.0-1.0-0.9-0.9-0.90.8
Pavlov. Cond. magazine entry number0.00.00.10.1-0.0-0.2-0.00.1-0.0-0.00.1-0.1-0.1-0.0-0.10.00.1-0.10.1-0.10.40.10.10.1-0.2
Pavlov. Cond. intertrial magazine entries1.52.23.0-0.7-1.2-1.41.31.41.4-1.51.5-1.5-1.61.51.3-1.41.6-1.6-1.5-1.61.61.61.71.6-1.7
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.10.60.5-0.6-0.7-0.40.5-0.50.60.6-0.4-0.30.3-0.60.60.30.6-0.8-0.6-0.6-0.60.7
Pavlov. Cond. response bias0.81.01.80.51.21.1-1.2-1.3-1.01.0-1.11.11.1-0.9-0.90.9-1.11.10.71.1-1.1-1.0-1.0-1.01.0
Time in closed arm before self-admin2.53.26.02.42.21.3-1.9-2.0-1.81.8-1.81.81.8-1.8-1.81.9-1.71.71.61.7-1.9-1.6-1.7-1.51.2
Time in closed arm after self-admin3.23.46.82.62.41.9-1.8-2.0-2.12.0-1.91.91.8-1.9-2.12.0-1.71.71.51.7-1.2-1.6-1.3-1.61.2
Time in open arm before self-admin0.50.53.6-1.9-0.7-0.10.50.60.4-0.60.5-0.4-0.50.70.7-0.70.5-0.5-1.0-0.41.30.30.70.3-0.1
Time in open arm after self-admin3.13.47.8-2.8-1.9-1.51.41.61.8-1.91.8-1.8-1.82.01.7-1.81.8-1.8-1.8-1.72.21.71.91.7-1.6
Bone: periosteal estimation0.40.91.30.11.10.9-1.1-1.0-1.01.0-1.01.01.0-1.0-1.00.9-1.11.10.91.0-0.4-1.0-1.1-1.00.9
Bone: periosteal perimeter1.22.03.01.31.71.5-1.6-1.7-1.51.5-1.51.51.4-1.4-1.51.4-1.41.41.61.4-1.0-1.3-1.4-1.31.1
Bone: post-yield work0.50.72.21.51.21.0-1.1-1.0-1.00.8-0.90.90.8-0.8-0.90.8-0.70.70.70.7-0.6-0.7-0.4-0.60.3
Progressive ratio test 1 active lever presses0.81.03.3-1.8-1.2-1.01.31.11.0-1.00.9-0.9-0.91.01.0-1.00.8-0.8-1.3-0.81.10.70.70.6-0.4
Progressive ratio test 1 breakpoint0.60.82.4-1.5-1.0-0.81.11.00.9-0.80.8-0.8-0.80.80.9-0.80.7-0.7-1.1-0.71.00.60.70.6-0.4
Progressive ratio test 1 inactive lever presses0.20.20.70.30.70.8-0.5-0.7-0.70.6-0.50.50.5-0.5-0.40.4-0.50.50.40.4-0.1-0.4-0.4-0.40.2
Progressive ratio test 2 active lever presses0.30.31.4-1.2-0.4-0.50.80.80.5-0.50.5-0.4-0.40.50.6-0.50.3-0.3-0.9-0.30.70.20.30.2-0.1
Progressive ratio test 2 breakpoint0.20.31.0-1.0-0.4-0.50.70.80.5-0.50.5-0.4-0.40.40.5-0.50.3-0.3-0.9-0.30.60.30.30.2-0.2
Progressive ratio test 2 inactive lever presses0.10.11.11.00.70.5-0.2-0.1-0.40.3-0.30.30.2-0.3-0.30.3-0.20.20.10.2-0.2-0.1-0.1-0.1-0.2
Incentive Sensitization - Responses0.00.00.3-0.50.3-0.0-0.10.10.00.0-0.00.10.1-0.10.1-0.0-0.20.2-0.30.10.0-0.1-0.3-0.10.1
Incentive Sensitization - Breakpoint0.00.10.3-0.40.40.0-0.2-0.1-0.10.2-0.20.20.2-0.20.00.1-0.30.3-0.00.3-0.2-0.3-0.5-0.20.2
Sum of active levers in priming session hrs 5-64.44.14.6-1.9-2.1-1.72.02.12.0-2.12.1-2.1-2.12.12.0-2.02.1-2.1-1.8-2.12.12.11.92.1-2.0
Progressive ratio0.20.44.42.10.40.2-0.5-0.6-0.30.2-0.1-0.0-0.1-0.2-0.40.40.2-0.20.8-0.3-0.10.40.30.4-1.0
Food seeking constrained by brief footshock0.20.21.00.2-0.2-0.30.10.10.00.2-0.20.30.3-0.40.10.2-0.50.50.70.5-1.0-0.6-0.6-0.61.0
Seeking ratio, punishment vs. effort0.50.85.9-2.4-1.0-1.01.01.10.9-0.80.6-0.5-0.40.71.0-0.90.3-0.2-1.1-0.20.40.00.1-0.00.7
Retroperitoneal fat weight0.41.83.3-0.01.81.0-1.5-1.4-1.31.3-1.41.51.5-1.2-0.91.0-1.51.50.81.5-1.5-1.5-1.4-1.41.6
Reaction time number correct0.20.41.81.21.30.6-1.2-1.2-0.60.5-0.50.50.4-0.3-0.50.4-0.20.20.10.20.2-0.00.00.1-0.5
Reaction time mean minus median0.82.07.3-2.7-1.9-1.41.61.41.4-1.51.4-1.3-1.31.51.6-1.51.2-1.2-1.4-1.11.21.01.11.0-0.5
Reaction time mean minus median AUC1.02.58.1-2.9-2.1-1.61.91.71.6-1.61.6-1.5-1.41.61.8-1.71.3-1.3-1.7-1.31.31.21.31.1-0.7
Reaction time num false alarms0.81.13.2-1.8-1.3-1.21.31.41.1-1.01.0-1.0-0.90.91.0-1.00.8-0.8-0.9-0.81.00.70.60.7-0.4
Reaction time num false alarms AUC0.81.33.7-1.9-1.4-1.31.41.51.3-1.11.1-1.1-1.01.11.2-1.20.9-0.9-1.1-0.91.10.80.70.8-0.5
Reaction time trials correct on left0.20.41.81.21.30.6-1.2-1.2-0.60.5-0.50.50.4-0.3-0.50.4-0.20.20.10.20.2-0.00.00.1-0.5
Reaction time trials on left0.20.41.71.21.30.5-1.2-1.2-0.60.4-0.40.50.4-0.3-0.40.3-0.20.20.00.20.2-0.00.00.1-0.5
Reaction time mean0.40.74.1-2.0-1.3-0.71.31.00.7-0.70.7-0.6-0.50.70.9-0.80.5-0.4-0.9-0.40.60.30.40.20.2
Reaction time mean AUC0.50.95.2-2.3-1.5-0.81.41.10.8-0.80.7-0.7-0.60.80.9-0.90.5-0.5-1.0-0.50.80.30.50.20.2
Median of all reaction times0.20.32.2-1.5-0.9-0.41.00.70.4-0.30.3-0.2-0.20.30.5-0.40.0-0.0-0.50.00.2-0.1-0.0-0.20.6
Reaction time omissions1.01.54.5-2.1-1.5-1.51.31.41.3-1.31.2-1.2-1.11.31.3-1.31.0-1.0-1.2-1.01.00.90.90.8-0.6
Reaction time false alarm rate0.91.24.3-2.1-1.7-1.41.61.71.3-1.11.1-1.0-0.90.91.1-1.00.8-0.7-0.8-0.70.60.60.40.5-0.0
Reaction time premature initiation rate0.50.73.6-1.9-1.0-0.80.50.50.8-0.80.7-0.7-0.70.91.0-0.90.7-0.7-0.8-0.61.00.60.70.7-0.5
Reaction time premature initiations0.40.62.4-1.6-0.3-0.6-0.0-0.00.6-0.70.6-0.6-0.60.90.9-0.90.7-0.7-0.9-0.71.30.80.80.8-0.8
Std. dev. reaction times0.91.77.4-2.7-1.8-1.31.61.41.2-1.31.2-1.1-1.11.31.4-1.41.0-0.9-1.3-0.91.10.80.90.7-0.3
Reaction time trials completed0.20.41.71.21.30.5-1.2-1.2-0.60.4-0.40.50.4-0.3-0.40.3-0.20.20.00.20.2-0.00.00.1-0.5
Reaction time trials AUC0.20.41.71.11.30.5-1.2-1.2-0.50.4-0.40.40.4-0.2-0.40.3-0.20.20.00.10.30.00.10.1-0.6
Run reversals in cocaine runway, females0.20.21.3-1.1-0.2-0.60.30.30.4-0.40.4-0.3-0.30.50.7-0.60.2-0.2-0.8-0.20.30.20.30.2-0.1
Run reversals in cocaine runway, males1.31.32.80.41.31.7-1.4-1.3-1.41.2-1.21.21.2-1.1-1.21.1-1.11.11.01.1-0.5-1.1-1.0-1.00.8
Latency to leave start box in cocaine runway5.15.89.53.12.42.5-2.5-2.6-2.62.5-2.42.42.3-2.4-2.62.5-2.22.22.62.2-2.4-2.1-1.9-2.11.8
Latency to leave start box in cocaine runway, F6.57.49.92.82.92.8-3.0-3.1-2.92.8-2.82.82.8-2.7-2.92.9-2.62.62.72.6-2.5-2.5-2.3-2.52.2
Latency to leave start box in cocaine runway, M0.60.53.21.80.40.8-0.4-0.4-0.70.7-0.60.50.5-0.8-0.60.7-0.60.51.10.5-1.1-0.5-0.6-0.50.4
Std. dev. time between licks in bursts0.91.21.70.11.10.8-1.2-1.2-0.91.0-1.11.11.2-1.0-0.90.9-1.21.21.11.2-1.2-1.2-1.3-1.21.3
Total sessions with >9 infusions0.10.11.0-1.0-0.30.00.10.0-0.00.1-0.10.10.1-0.1-0.10.1-0.20.20.30.20.2-0.2-0.3-0.30.3
Short access day 1 total inactive lever presses1.92.67.3-0.6-0.7-1.00.40.51.3-1.51.6-1.6-1.61.71.6-1.71.7-1.7-1.5-1.91.92.01.72.2-2.7
Short access day 10 total inactive lever presses0.51.23.81.91.51.2-1.4-1.4-1.21.0-1.01.01.0-1.0-1.01.0-0.90.90.90.8-1.3-0.7-0.8-0.70.5
Short access day 1 total infusions0.10.11.7-1.3-0.3-0.0-0.1-0.30.3-0.20.1-0.10.00.20.5-0.3-0.10.10.10.00.1-0.0-0.2-0.00.2
Short access day 10 total infusions0.20.30.7-0.20.20.30.0-0.0-0.30.5-0.40.50.5-0.5-0.40.5-0.60.60.50.6-0.6-0.6-0.8-0.70.8
Short access total infusions0.10.10.3-0.50.20.4-0.3-0.4-0.30.3-0.40.40.4-0.3-0.20.3-0.40.40.40.4-0.0-0.4-0.5-0.40.4
Short access day 1 locomotion0.91.22.70.80.70.8-0.6-0.5-0.81.0-1.01.01.1-1.1-0.81.0-1.21.21.31.2-1.6-1.2-1.5-1.21.4
Short access day 10 total locomotion0.51.03.00.00.10.5-0.0-0.0-0.40.7-0.70.80.9-0.9-0.50.7-1.21.20.91.1-1.6-1.2-1.7-1.31.7
Short access total locomotion0.70.92.20.40.30.7-0.3-0.2-0.70.9-0.80.80.9-1.0-0.70.9-1.11.11.21.0-1.3-1.1-1.5-1.11.3
One hour access (0.3 mA shock)0.50.61.2-1.0-0.7-0.90.80.90.8-0.80.8-0.7-0.70.80.8-0.80.7-0.7-1.1-0.70.90.70.70.7-0.7
Compulsive drug intake3.64.35.9-1.6-2.0-1.72.02.01.9-2.02.1-2.1-2.22.11.8-1.92.3-2.3-1.9-2.22.42.22.32.2-2.3
One hour access (shock baseline)1.11.72.31.01.11.0-1.1-0.9-1.11.3-1.31.41.4-1.3-1.21.3-1.51.51.01.4-1.5-1.5-1.5-1.51.5
Social response proportion1.92.13.8-1.5-1.8-1.91.81.71.7-1.51.5-1.5-1.41.41.6-1.61.3-1.3-1.3-1.31.01.21.11.2-0.9
Social responses0.10.10.5-0.5-0.2-0.70.10.10.4-0.30.2-0.2-0.20.30.4-0.40.1-0.1-0.4-0.20.10.2-0.00.2-0.2
Social time0.10.10.50.70.30.5-0.4-0.4-0.50.3-0.30.30.3-0.3-0.20.2-0.20.20.30.2-0.3-0.2-0.2-0.2-0.1
Soleus weight1.64.75.52.32.32.1-2.1-2.0-2.32.2-2.22.22.2-2.2-2.32.3-2.12.11.92.1-2.2-2.1-2.0-2.12.0
Bone: stiffness0.10.10.3-0.30.60.5-0.4-0.2-0.40.3-0.30.40.4-0.2-0.10.1-0.40.4-0.20.40.1-0.4-0.1-0.30.3
Tibialis anterior weight0.20.72.0-1.4-0.4-0.60.60.50.7-0.80.7-0.7-0.70.90.8-0.90.8-0.7-1.1-0.71.20.70.90.8-0.6
Time to tail flick, vehicle, before self-admin3.43.67.00.6-1.7-1.41.92.01.6-1.81.9-2.0-2.11.81.4-1.62.1-2.2-1.5-2.21.92.22.02.2-2.6
Time to tail flick, vehicle, after self-admin0.81.03.31.81.51.0-1.4-1.4-1.10.9-0.91.00.9-0.9-1.11.0-0.80.80.80.8-0.6-0.7-0.5-0.60.3
Time to tail flick, test, before self-admin0.40.41.21.10.70.6-0.6-0.7-0.70.6-0.60.60.6-0.6-0.70.6-0.50.50.60.5-0.6-0.5-0.6-0.40.2
Time to tail flick, test, after self-admin0.50.61.61.30.90.8-1.0-0.9-0.80.8-0.80.80.7-0.7-0.80.7-0.60.60.50.6-0.6-0.6-0.4-0.50.4
Delta time to tail flick, vehicle, before/after SA4.74.57.01.42.51.8-2.5-2.7-2.12.1-2.22.22.2-2.1-2.02.1-2.22.21.92.2-1.9-2.1-2.0-2.12.0
Delta time to tail flick, test, before/after SA0.40.40.6-0.8-0.7-0.70.40.60.7-0.70.6-0.6-0.60.70.7-0.70.6-0.6-0.7-0.60.60.60.70.6-0.3
Tibia length0.61.73.11.81.71.0-1.5-1.5-1.41.3-1.31.31.3-1.2-1.51.4-1.21.21.11.2-1.2-1.2-1.1-1.10.9
Ambulatory time before self-admin0.20.42.5-1.6-0.7-0.50.60.80.7-0.60.5-0.4-0.40.50.8-0.70.3-0.3-0.7-0.30.50.20.20.20.1
Ambulatory time after self-admin0.50.54.1-2.00.5-0.0-0.4-0.1-0.20.3-0.50.60.7-0.40.00.2-0.80.8-0.30.8-0.2-0.9-0.6-0.91.4
Bone: tissue strength0.60.61.71.11.31.1-1.1-1.1-0.90.8-0.80.80.7-0.6-0.80.7-0.60.60.40.6-0.4-0.5-0.4-0.50.3
Total heroin consumption1.21.41.9-0.4-1.1-1.01.11.11.1-1.21.2-1.3-1.31.21.0-1.11.3-1.3-1.1-1.31.31.31.21.3-1.4
Bone: trabecular number0.61.01.50.90.70.5-0.5-0.6-0.91.0-0.90.91.0-1.1-1.01.0-1.11.11.21.1-1.2-1.1-1.2-1.11.2
Bone: trabecular spacing0.00.10.6-0.8-0.10.2-0.1-0.10.1-0.10.1-0.1-0.10.20.2-0.20.2-0.2-0.3-0.20.40.20.10.2-0.1
Bone: trabecular thickness3.13.86.51.12.41.7-2.4-2.6-2.02.0-2.02.12.1-1.9-1.91.8-2.02.01.82.0-1.5-1.9-1.9-1.81.6
Bone: trabecular tissue density0.10.10.4-0.6-0.2-0.40.10.00.3-0.30.3-0.3-0.30.30.4-0.40.3-0.3-0.3-0.30.20.30.30.3-0.2
Water consumed over 24 hours0.10.10.30.2-0.5-0.30.40.40.2-0.20.2-0.3-0.30.20.0-0.10.4-0.4-0.2-0.30.50.30.50.3-0.5
Number of responses in last shaping day0.60.71.60.61.21.3-1.2-1.0-1.10.9-0.90.90.9-0.8-0.90.8-0.70.70.50.7-0.3-0.7-0.6-0.60.3