Hub : Genes

Shtn1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_268125408_268128926 0.02 0.02 5.2e-03 0 0.01 0.01 0.01 7.8e-02 4.8e-03 1.7e-02 2.7e-02
2 NAcc intron excision ratio chr1_268185694_268187776 0.06 0.04 1.2e-07 0.05 0.04 0.04 0.04 2.6e-08 2.1e-07 4.0e-07 2.8e-07
3 NAcc intron excision ratio chr1_268185694_268196058 0.05 0.03 4.6e-07 0.05 0.04 0.04 0.04 9.3e-08 8.9e-07 2.1e-06 8.4e-07
4 pVTA intron excision ratio chr1_268129046_268134022 0.04 0.03 8.8e-03 0 0.02 0.03 0.02 2.8e-01 4.6e-03 2.6e-03 1.5e-02
5 pVTA isoform ratio NM_001303537.1 0.03 0.02 2.1e-03 0.02 0.02 0.01 0.02 9.6e-03 6.1e-03 9.2e-02 1.4e-02
6 pVTA isoform ratio NM_001079705.4 0.03 0.02 3.1e-03 0.02 0.02 0 0.02 1.2e-02 7.7e-03 1.9e-01 1.3e-02
7 NAcc gene expression Shtn1 0.3 0.1 0.0e+00 0.38 0.39 0.39 0.39 4.3e-62 1.2e-63 1.4e-62 3.1e-63
8 IL gene expression Shtn1 0.74 0.11 1.8e-15 0.43 0.43 0.41 0.43 1.6e-11 1.8e-11 5.1e-11 1.1e-11
9 pVTA gene expression Shtn1 0.31 0.12 0.0e+00 0.3 0.35 0.34 0.34 1.1e-24 3.2e-29 5.1e-28 1.3e-28
10 PL gene expression Shtn1 0.38 0.11 0.0e+00 0.46 0.48 0.47 0.47 2.2e-55 1.4e-58 3.9e-58 6.1e-58
11 OFC mRNA stability Shtn1 0.26 0.14 2.1e-04 0.07 0.14 0.14 0.11 1.2e-02 3.4e-04 4.4e-04 1.2e-03
12 Brain gene expression Shtn1 0.67 0.16 0.0e+00 0.58 0.59 0.59 0.6 9.9e-66 1.1e-67 3.5e-68 2.0e-69
13 BLA mRNA stability Shtn1 0.07 0.05 1.5e-03 0.07 0.04 0.06 0.06 1.1e-04 2.3e-03 3.4e-04 2.5e-04
14 BLA gene expression Shtn1 0.52 0.13 0.0e+00 0.41 0.48 0.47 0.49 5.7e-23 3.6e-28 2.0e-27 5.6e-29
15 pVTA intron excision ratio chr1_268185694_268187776 0.07 0.04 2.2e-06 0.09 0.07 0.08 0.08 9.6e-08 1.3e-06 5.9e-07 6.3e-07
16 pVTA intron excision ratio chr1_268185694_268196058 0.07 0.04 2.2e-06 0.09 0.07 0.08 0.08 8.2e-08 1.9e-06 7.8e-07 5.8e-07
17 IC gene expression Shtn1 0.8 0.12 0.0e+00 0.56 0.57 0.58 0.57 4.2e-28 3.0e-28 4.4e-29 1.8e-28
18 NAcc mRNA stability Shtn1 0.06 0.03 4.8e-12 0.08 0.08 0.08 0.08 2.6e-12 7.4e-12 1.0e-11 3.8e-12
19 pVTA intron excision ratio chr1_268109798_268125216 0.04 0.03 6.4e-04 0.04 0.03 0.01 0.03 2.2e-04 2.9e-03 3.1e-02 1.2e-03
20 pVTA intron excision ratio chr1_268109798_268134022 0.06 0.04 3.3e-05 0.07 0.05 0.06 0.06 1.9e-06 4.5e-05 6.7e-06 8.4e-06
21 PL mRNA stability Shtn1 0.06 0.04 1.5e-06 0.06 0.05 0.05 0.06 5.2e-07 1.7e-06 4.4e-06 4.8e-07
22 IL mRNA stability Shtn1 0.21 0.12 2.1e-03 0.1 0.06 0.06 0.07 2.0e-03 1.9e-02 1.4e-02 7.6e-03
23 OFC gene expression Shtn1 0.51 0.16 2.1e-08 0.26 0.23 0.21 0.22 8.0e-07 2.7e-06 1.1e-05 7.5e-06
24 RMTg intron excision ratio chr1_268185694_268196058 0.18 0.1 8.6e-04 0.12 0.14 0.14 0.13 3.5e-04 1.3e-04 1.7e-04 3.2e-04
25 RMTg intron excision ratio chr1_268185694_268187776 0.16 0.1 1.6e-03 0.11 0.12 0.12 0.12 7.1e-04 3.6e-04 5.8e-04 5.3e-04
26 Brain mRNA stability Shtn1 0.38 0.14 0.0e+00 0.37 0.4 0.4 0.41 2.0e-36 1.2e-39 3.3e-40 8.0e-41

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density1.83.16.72.62.1-2.1-0.4-2.22.12.12.12.12.01.51.91.51.81.5-1.51.61.51.8-1.81.71.71.7-0.70.71.3
Area under the delay curve1.11.33.7-0.30.5-0.5-1.90.7-0.8-0.8-0.6-0.6-0.9-1.4-0.9-1.4-1.1-1.31.3-1.2-1.2-1.01.0-1.1-1.1-1.11.8-1.8-1.5
BMI with tail1.34.735.44.63.6-3.6-5.9-2.32.11.91.91.81.81.11.30.40.80.5-0.50.50.50.4-0.40.50.50.52.1-2.1-0.3
BMI without tail0.92.620.33.62.4-2.4-4.5-1.81.71.51.51.41.41.31.00.50.80.6-0.60.50.40.4-0.40.60.60.61.3-1.4-0.1
Body weight1.98.434.35.95.0-5.0-5.4-3.53.33.13.33.03.01.82.51.61.81.7-1.71.61.41.5-1.51.61.61.61.6-1.60.5
Weight adjusted by age0.10.22.90.90.4-0.4-1.7-0.20.20.10.10.10.20.4-0.2-0.20.10.1-0.1-0.3-0.4-0.10.1-0.0-0.0-0.00.6-0.6-0.5
Bone surface1.32.44.92.21.5-1.5-0.3-1.91.81.81.71.81.71.51.71.41.61.3-1.31.41.41.7-1.71.51.61.6-0.80.81.3
Bone volume0.71.34.32.11.9-1.9-1.5-1.41.41.31.41.41.20.71.10.70.90.6-0.60.80.71.0-1.00.80.90.90.2-0.20.5
Breakpoint value in progressive ratio session0.30.42.70.81.7-1.7-0.4-0.50.50.40.70.50.4-0.70.50.40.0-0.10.10.10.20.1-0.10.10.10.10.9-0.9-0.4
Number of licking bursts2.03.24.11.71.1-1.11.5-1.81.81.81.81.81.91.71.91.92.01.9-1.91.92.01.8-1.82.02.02.0-1.71.71.9
Context. condit. distance diff. score0.20.30.90.1-0.60.60.5-0.20.30.30.00.20.30.90.30.40.50.5-0.50.50.50.5-0.50.50.50.5-0.90.90.7
Locomotion velocity, session 10.00.00.2-0.2-0.30.30.40.1-0.1-0.1-0.1-0.1-0.00.1-0.00.20.00.1-0.10.10.20.0-0.00.00.00.0-0.20.20.1
Locomotion distance, session 10.30.42.6-1.0-1.61.60.50.7-0.7-0.7-0.8-0.7-0.60.1-0.6-0.3-0.3-0.40.4-0.3-0.2-0.30.3-0.3-0.3-0.3-0.40.40.0
Locomotion velocity, session 20.50.63.6-1.2-1.91.91.40.7-0.7-0.7-0.9-0.8-0.60.4-0.5-0.0-0.2-0.00.0-0.1-0.0-0.10.1-0.2-0.1-0.1-0.90.90.3
Locomotion distance, session 20.20.32.0-0.4-1.41.4-0.20.4-0.4-0.4-0.7-0.5-0.40.6-0.4-0.2-0.1-0.30.3-0.2-0.0-0.10.1-0.1-0.1-0.1-0.40.40.2
Locomotion velocity, session 30.20.21.3-0.7-1.11.10.50.5-0.4-0.4-0.5-0.5-0.40.2-0.3-0.2-0.1-0.10.1-0.2-0.1-0.10.1-0.1-0.1-0.1-0.50.50.1
Locomotion distance, session 30.60.62.8-1.1-1.71.7-0.10.9-0.9-0.9-1.1-1.0-0.80.1-0.9-0.7-0.5-0.50.5-0.6-0.6-0.50.5-0.5-0.5-0.5-0.20.2-0.2
Stereotopy head waving bouts, day 30.30.40.8-0.9-0.50.50.30.7-0.7-0.7-0.6-0.7-0.7-0.8-0.6-0.6-0.7-0.60.6-0.6-0.6-0.60.6-0.6-0.6-0.60.4-0.4-0.6
Stereotopy head waving duration, day 30.00.00.4-0.30.2-0.20.70.1-0.1-0.10.00.0-0.1-0.50.0-0.1-0.1-0.10.1-0.00.0-0.00.0-0.1-0.0-0.00.0-0.0-0.1
Locomotion velocity, session 70.30.31.10.4-0.50.50.4-0.40.40.40.20.30.51.10.40.50.60.6-0.60.50.50.6-0.60.60.60.6-0.80.80.7
Locomotion distance, session 70.10.11.0-0.1-1.01.00.00.1-0.1-0.2-0.4-0.3-0.10.8-0.2-0.00.10.1-0.10.00.00.1-0.10.10.10.1-0.50.50.3
Stereotopy head waving bouts, day 70.00.00.20.10.3-0.3-0.40.0-0.0-0.00.00.0-0.1-0.3-0.1-0.1-0.2-0.20.2-0.1-0.1-0.10.1-0.2-0.1-0.10.4-0.4-0.3
Stereotopy head waving duration, day 70.20.21.00.21.0-1.0-0.5-0.10.00.00.30.2-0.1-0.9-0.0-0.2-0.3-0.30.3-0.2-0.2-0.30.3-0.3-0.3-0.30.8-0.8-0.6
Locomotion velocity, session 81.62.04.20.5-0.50.51.9-1.01.11.10.81.01.11.71.21.51.51.5-1.51.51.61.5-1.51.51.51.5-2.02.01.8
Locomotion distance, session 81.62.46.60.3-1.61.61.9-0.80.90.80.40.71.02.50.91.41.51.4-1.41.41.51.5-1.51.51.51.5-2.62.62.1
Degree of sensitization distance0.60.61.21.11.0-1.00.1-0.90.90.90.90.80.90.60.80.70.70.7-0.70.70.70.7-0.70.70.70.7-0.30.30.5
Degree of sensitization stereotypy0.30.31.01.01.0-1.0-0.7-0.70.70.70.70.70.60.20.50.40.40.3-0.30.40.40.4-0.40.40.40.40.2-0.20.2
Conditioned locomotion0.20.20.5-0.40.1-0.1-0.30.4-0.4-0.4-0.4-0.4-0.4-0.7-0.4-0.4-0.7-0.40.4-0.4-0.3-0.60.6-0.6-0.7-0.70.6-0.6-0.6
Cocaine response after cond. corrected2.53.08.8-2.7-3.03.00.92.1-2.0-2.0-2.3-2.1-1.9-0.8-1.7-1.4-1.5-1.31.3-1.4-1.4-1.41.4-1.4-1.4-1.4-0.10.1-0.7
Cocaine response after cond. not corrected1.72.06.6-2.5-2.62.61.41.7-1.7-1.6-1.8-1.7-1.5-0.6-1.3-0.9-1.1-0.90.9-1.0-1.0-1.01.0-1.1-1.1-1.1-0.40.4-0.3
Cocaine response before conditioning1.01.21.71.11.3-1.31.0-1.21.21.11.31.21.20.61.21.21.11.2-1.21.11.11.0-1.01.11.11.1-0.70.70.9
Saline control response0.30.40.7-0.8-0.90.9-0.40.7-0.7-0.7-0.8-0.7-0.7-0.3-0.8-0.6-0.5-0.70.7-0.6-0.6-0.50.5-0.5-0.5-0.50.2-0.2-0.5
Bone: connectivity density1.52.43.71.91.4-1.40.2-1.81.81.71.81.81.71.41.71.41.61.4-1.41.51.41.7-1.71.61.61.6-1.01.01.4
Bone: cortical apparent density1.72.47.7-2.6-2.82.81.21.9-1.8-1.8-1.9-1.9-1.7-0.7-1.6-1.1-1.2-1.11.1-1.2-1.1-1.11.1-1.1-1.1-1.1-0.30.3-0.6
Bone: cortical area2.33.59.33.12.0-2.0-1.3-2.32.32.22.12.22.12.01.91.71.91.7-1.71.71.61.8-1.81.81.81.8-0.70.71.4
Bone: cortical porosity0.10.10.60.60.8-0.80.0-0.40.40.40.50.50.4-0.00.40.30.20.3-0.30.30.30.2-0.20.20.20.20.2-0.20.0
Bone: cortical porosity0.60.72.11.31.5-1.5-0.2-1.01.01.01.11.00.90.30.90.70.60.7-0.70.70.70.6-0.60.60.60.60.1-0.10.3
Bone: cortical thickness1.42.25.62.20.6-0.6-0.9-1.71.71.61.31.51.62.41.31.41.61.5-1.51.41.41.6-1.61.51.51.5-1.11.11.5
Bone: cortical thickness0.10.22.60.6-0.10.1-1.6-0.10.0-0.0-0.3-0.1-0.10.5-0.2-0.3-0.2-0.20.2-0.3-0.3-0.10.1-0.2-0.2-0.20.4-0.4-0.2
Bone: cortical tissue density1.72.47.6-2.6-2.82.81.41.9-1.8-1.8-1.9-1.9-1.7-0.7-1.6-1.1-1.2-1.11.1-1.1-1.1-1.11.1-1.1-1.1-1.1-0.30.3-0.6
Condit. Reinf. active minus inactive responses0.91.12.20.5-0.20.21.5-0.80.80.80.70.80.91.30.91.01.11.1-1.11.01.01.1-1.11.11.11.1-1.41.41.3
Condit. Reinf. active-inactive response ratio0.60.72.70.20.1-0.11.6-0.60.60.60.60.60.70.70.70.70.80.9-0.90.80.80.8-0.80.90.90.9-1.11.10.9
Condit. Reinf. active responses1.92.44.51.60.3-0.30.8-1.61.61.51.31.41.62.11.51.51.71.7-1.71.61.61.6-1.61.71.61.6-1.61.61.7
Condit. Reinf. inactive responses1.92.34.52.10.6-0.6-0.1-1.71.71.61.41.51.72.11.51.51.61.6-1.61.51.51.6-1.61.61.61.6-1.31.31.6
Incentive salience index mean0.60.71.80.3-0.70.71.2-0.50.60.50.30.40.61.30.60.70.90.9-0.90.80.80.9-0.90.90.80.8-1.31.31.1
Condit. Reinf. lever presses0.10.10.6-0.0-0.80.80.50.00.0-0.0-0.2-0.10.10.7-0.00.00.20.2-0.20.10.10.2-0.20.20.20.2-0.50.50.4
Condit. Reinf. active minus inactive responses0.91.13.41.51.8-1.8-0.1-1.21.21.21.51.31.10.31.10.81.00.7-0.70.80.70.9-0.91.01.01.0-0.00.00.5
Condit. Reinf. active-inactive response ratio0.30.41.41.01.2-1.2-0.4-0.70.70.70.90.80.60.20.60.40.60.2-0.20.40.40.4-0.40.60.60.60.2-0.20.2
Condit. Reinf. active responses1.31.85.42.02.3-2.3-0.5-1.61.61.51.81.71.40.51.41.01.30.9-0.91.01.01.2-1.21.31.31.30.00.00.6
Condit. Reinf. inactive responses0.50.62.01.21.4-1.4-0.3-1.00.90.91.11.00.90.30.80.60.70.5-0.50.60.50.7-0.70.70.70.70.1-0.10.3
Condit. Reinf. lever presses0.50.61.71.31.3-1.3-0.7-1.01.00.91.01.00.90.40.80.60.70.4-0.40.60.50.8-0.80.70.60.60.0-0.00.4
Condit. Reinf. lever reinforcers received1.31.93.91.92.0-2.0-0.0-1.61.61.61.81.71.50.81.41.21.41.1-1.11.21.11.4-1.41.41.41.4-0.40.40.9
Conditioned reinforcement - actives0.50.82.6-1.5-1.61.60.71.1-1.0-1.0-1.1-0.9-1.0-0.4-0.8-0.9-0.6-1.21.2-0.7-0.7-0.60.6-0.6-0.6-0.6-0.20.2-0.2
Conditioned reinforcement - inactives0.10.10.50.20.7-0.70.3-0.30.30.40.30.60.2-0.30.7-0.10.20.2-0.20.20.30.3-0.30.20.20.20.0-0.00.3
Conditioned locomotion0.81.13.9-1.7-2.02.01.01.2-1.1-1.1-1.3-1.0-1.1-0.2-1.1-1.0-0.6-1.01.0-0.7-0.8-0.60.6-0.6-0.6-0.6-0.50.5-0.2
Patch foraging indifference point 0 sec0.40.82.91.70.9-0.9-1.5-1.11.01.00.90.91.01.10.70.90.80.6-0.60.80.70.8-0.80.70.70.7-0.10.10.5
Patch foraging indifference point AUC0.20.31.20.91.0-1.0-1.1-0.70.60.60.70.70.50.10.60.50.30.1-0.10.40.40.3-0.30.20.20.20.3-0.30.1
Delay disc. indifference point, 0s delay0.40.41.0-0.4-0.50.5-1.00.6-0.6-0.6-0.8-0.7-0.6-0.3-0.7-0.7-0.7-0.50.5-0.7-0.7-0.70.7-0.7-0.7-0.70.5-0.5-0.6
Delay disc. indifference point, 16s delay0.91.02.6-0.20.4-0.4-1.60.6-0.6-0.7-0.5-0.5-0.8-1.2-0.8-1.2-0.9-1.31.3-1.1-1.0-0.70.7-0.9-0.9-0.91.6-1.5-1.3
Delay disc. indifference point, 2s delay2.62.93.7-1.6-0.80.8-1.41.8-1.8-1.8-1.7-1.8-1.8-1.8-1.8-1.7-1.9-1.61.6-1.9-1.9-1.81.8-1.9-1.9-1.91.7-1.7-1.9
Delay disc. indifference point, 24s delay0.20.31.80.60.8-0.8-1.4-0.20.20.20.30.30.0-0.50.0-0.3-0.1-0.50.5-0.3-0.2-0.00.0-0.1-0.1-0.10.9-0.9-0.5
Delay disc. indifference point, 4s delay1.21.32.5-0.50.3-0.3-1.60.9-0.9-0.9-0.7-0.8-1.0-1.4-1.0-1.4-1.1-1.41.4-1.2-1.3-1.01.0-1.1-1.1-1.11.6-1.6-1.4
Delay disc. indifference point, 8s delay0.81.02.4-0.30.5-0.5-1.50.6-0.7-0.7-0.5-0.5-0.8-1.3-0.7-1.2-1.0-1.21.2-1.1-1.0-0.80.8-1.0-1.0-1.01.6-1.6-1.3
Indifference point function ln k0.10.10.5-0.1-0.50.50.70.00.0-0.0-0.1-0.10.10.5-0.10.10.20.3-0.30.10.20.1-0.10.20.20.2-0.50.50.2
Indifference point function log k0.10.10.5-0.1-0.50.50.70.00.0-0.0-0.1-0.10.10.5-0.10.10.20.3-0.30.10.20.1-0.10.20.20.2-0.50.50.2
Patch foraging total patch changes 0 sec0.61.03.81.91.1-1.1-1.6-1.31.21.21.01.11.11.20.91.00.90.8-0.80.90.90.9-0.90.80.70.7-0.10.10.5
Patch foraging total patch changes 12 sec0.91.13.71.91.3-1.3-1.4-1.41.31.31.11.21.21.11.11.10.90.7-0.71.01.01.0-1.00.80.70.7-0.10.10.7
Patch foraging total patch changes 18 sec0.71.03.41.81.6-1.6-1.6-1.21.21.11.51.21.10.41.00.80.80.5-0.50.80.60.8-0.80.80.80.80.4-0.40.2
Patch foraging total patch changes 24 sec0.50.92.51.61.4-1.4-0.8-1.21.21.11.21.11.10.61.11.00.80.8-0.81.00.90.7-0.70.70.70.7-0.00.00.5
Patch foraging total patch changes 6 sec1.42.15.72.41.6-1.6-1.2-1.81.71.71.51.61.61.51.51.71.21.5-1.51.51.41.3-1.31.11.11.1-0.50.51.0
Patch foraging time to switch 0 sec0.51.02.7-1.7-0.60.61.11.2-1.2-1.2-1.0-1.1-1.1-1.4-0.9-1.0-1.1-0.70.7-1.0-1.1-1.11.1-1.0-1.0-1.00.5-0.5-0.8
Patch foraging water rate 0 sec0.40.83.11.80.7-0.7-1.5-1.11.11.00.81.01.01.30.70.90.80.7-0.70.80.90.8-0.80.70.70.7-0.20.20.5
Patch foraging water rate 12 sec0.81.74.22.11.2-1.2-1.0-1.61.51.51.51.41.51.41.31.31.31.2-1.21.21.31.3-1.31.31.31.3-0.50.51.0
Patch foraging water rate 18 sec0.10.10.50.0-0.60.6-0.70.2-0.3-0.3-0.4-0.4-0.30.3-0.5-0.2-0.1-0.40.4-0.3-0.3-0.20.2-0.2-0.2-0.20.2-0.2-0.3
Patch foraging water rate 24 sec0.50.62.9-0.1-0.40.4-1.70.6-0.6-0.7-0.7-0.8-0.6-0.3-0.9-0.8-0.8-0.70.7-0.8-0.8-0.80.8-0.8-0.8-0.81.0-1.0-1.0
Patch foraging water rate 6 sec0.10.11.30.4-0.10.1-1.20.1-0.1-0.1-0.1-0.2-0.10.2-0.3-0.2-0.1-0.20.2-0.3-0.3-0.30.3-0.2-0.1-0.10.5-0.5-0.4
Seeking ratio, delayed vs. immediate footshock0.40.53.1-1.1-1.31.31.80.4-0.3-0.2-0.6-0.3-0.20.4-0.10.40.00.2-0.20.30.40.1-0.10.10.10.1-1.21.20.6
Distance traveled before self-admin3.95.18.5-2.9-2.92.9-0.42.7-2.6-2.6-2.5-2.7-2.5-1.5-2.5-2.5-2.1-2.42.4-2.2-2.2-2.12.1-2.1-2.1-2.11.0-1.0-1.7
Distance traveled after self-admin2.63.25.4-2.3-1.91.9-0.22.1-2.0-2.0-2.0-2.0-2.0-1.6-1.9-1.9-1.8-1.91.9-1.8-1.7-1.81.8-1.8-1.8-1.81.0-1.0-1.5
Extensor digitorum longus weight0.31.18.61.61.9-1.9-2.9-0.60.50.40.50.50.3-0.40.3-0.4-0.4-0.20.2-0.3-0.3-0.30.3-0.5-0.5-0.51.7-1.7-0.8
Bone: elastic displacement1.01.11.7-1.0-0.50.5-0.71.1-1.1-1.1-1.0-1.1-1.1-1.1-1.2-1.1-1.2-1.11.1-1.1-1.1-1.11.1-1.2-1.2-1.21.1-1.1-1.3
Bone: elastic work1.41.82.7-1.0-1.11.1-1.61.3-1.3-1.4-1.5-1.4-1.4-0.8-1.5-1.4-1.4-1.31.3-1.4-1.4-1.31.3-1.5-1.5-1.51.2-1.2-1.4
Bone: endosteal estimation0.20.41.51.21.2-1.2-0.7-0.80.80.80.80.80.70.20.70.40.40.4-0.40.40.50.4-0.40.40.40.40.3-0.30.2
Bone: endosteal perimeter0.30.63.20.81.5-1.5-1.8-0.20.20.10.40.20.0-0.80.0-0.3-0.4-0.40.4-0.4-0.4-0.40.4-0.4-0.4-0.41.3-1.3-0.8
Epididymis fat weight3.913.446.46.86.2-6.2-4.9-4.54.34.14.64.23.92.13.32.32.92.5-2.52.42.12.5-2.52.72.72.71.2-1.20.9
Delta time in closed arm before/after self-admin0.20.20.8-0.6-0.90.90.70.5-0.4-0.4-0.7-0.6-0.30.3-0.4-0.1-0.30.1-0.1-0.2-0.3-0.40.4-0.3-0.3-0.3-0.50.50.0
Delta time in open arm before/after self-admin2.22.24.81.72.2-2.20.7-1.71.61.62.01.81.60.41.71.41.41.4-1.41.31.41.4-1.41.41.41.4-0.40.50.9
Diff in mean of infusions in LGA sessions0.20.21.10.51.1-1.1-0.7-0.30.30.30.40.40.2-0.50.40.4-0.0-0.20.20.10.3-0.00.0-0.0-0.0-0.00.6-0.6-0.1
Delay discount exponential model param1.51.64.10.4-0.50.52.0-0.90.90.90.70.71.01.61.01.51.31.5-1.51.41.31.1-1.11.31.31.3-2.02.01.7
Extinction: sum of active levers before priming0.30.41.40.51.1-1.1-0.9-0.10.10.00.40.3-0.0-0.9-0.1-0.3-0.1-0.60.6-0.6-0.4-0.10.1-0.1-0.1-0.11.2-1.2-0.9
Active lever presses in extinction session 60.10.10.60.20.5-0.5-0.70.1-0.1-0.10.20.0-0.1-0.6-0.2-0.0-0.1-0.40.4-0.4-0.3-0.10.1-0.1-0.1-0.10.8-0.8-0.7
Bone: final force1.11.74.82.20.9-0.9-1.1-1.61.61.51.31.51.51.81.21.11.41.1-1.11.11.11.3-1.31.31.31.3-0.60.61.1
Bone: final moment1.01.74.62.21.0-1.0-1.0-1.61.61.51.31.51.51.71.21.11.31.2-1.21.11.11.3-1.31.31.31.3-0.60.61.1
Food consumed during 24 hour testing period0.30.40.90.1-0.40.40.9-0.40.40.40.30.40.40.80.50.70.60.5-0.50.70.70.7-0.70.60.60.6-0.90.90.8
Glucose0.40.63.41.21.7-1.7-1.8-0.50.40.40.50.40.3-0.50.1-0.2-0.2-0.20.2-0.1-0.2-0.20.2-0.3-0.3-0.31.2-1.2-0.7
Heart weight2.03.18.32.91.7-1.7-1.0-2.22.12.02.02.02.02.01.71.61.81.5-1.51.51.51.7-1.71.81.71.7-0.70.71.3
Delay discount hyperbolic model param1.82.04.40.5-0.40.42.1-1.01.01.10.80.91.21.81.21.71.41.6-1.61.51.51.2-1.21.41.41.4-2.12.11.8
Intermittent access intake day 1-15 change0.81.62.4-1.3-0.70.7-0.41.4-1.4-1.4-1.2-1.5-1.3-1.5-1.3-1.1-1.5-0.80.8-1.2-1.3-1.41.4-1.5-1.5-1.51.2-1.2-1.4
Intermittent access intake escalation0.40.91.4-1.0-0.40.4-0.11.0-1.0-1.1-0.9-1.2-1.0-1.2-1.0-0.7-1.1-0.50.5-0.9-1.0-1.01.0-1.1-1.1-1.10.9-0.9-1.0
Intermittent access intake escalation 20.30.30.6-0.7-0.50.50.20.7-0.7-0.7-0.7-0.8-0.6-0.6-0.6-0.5-0.7-0.30.3-0.5-0.6-0.60.6-0.7-0.7-0.70.3-0.3-0.5
Intermitt. access day 1 inactive lever presses0.41.75.31.72.3-2.30.4-1.51.51.51.61.61.40.11.61.00.91.3-1.31.11.11.2-1.21.01.01.0-0.10.10.7
Intermitt. access day 15 inactive lever presses0.10.20.80.70.9-0.9-0.6-0.50.50.40.60.50.4-0.00.40.00.20.4-0.40.30.20.4-0.40.20.20.20.3-0.3-0.1
Intermitt. access escalation Index0.00.10.6-0.20.2-0.20.8-0.10.10.10.10.20.1-0.10.30.60.00.3-0.30.30.30.2-0.20.10.10.1-0.20.20.2
Intermittent access day 1 total infusions0.20.30.6-0.6-0.30.3-0.20.6-0.6-0.6-0.5-0.5-0.6-0.7-0.4-0.8-0.6-0.60.6-0.6-0.7-0.50.5-0.5-0.5-0.50.5-0.5-0.5
Intermittent access day 15 total infusions0.91.32.5-1.3-0.40.4-0.31.3-1.3-1.3-1.0-1.3-1.2-1.6-1.0-1.1-1.3-0.90.9-1.1-1.3-1.21.2-1.3-1.3-1.31.2-1.2-1.2
Intermittent access terminal intake (last 3 days)0.71.02.0-1.0-0.20.2-0.61.0-1.0-1.0-0.8-1.0-1.0-1.4-0.8-1.0-1.1-0.90.9-1.0-1.1-1.11.1-1.1-1.1-1.11.2-1.2-1.0
Intermittent access total infusions0.30.40.7-0.7-0.20.2-0.20.7-0.7-0.7-0.6-0.7-0.7-0.9-0.4-0.7-0.7-0.70.7-0.6-0.8-0.70.7-0.7-0.7-0.70.7-0.7-0.6
Intermittent access day 1 locomotion2.53.14.1-1.9-1.21.2-0.91.9-1.9-1.9-1.9-1.9-1.9-1.7-1.8-2.0-1.9-1.81.8-1.9-1.9-1.91.9-1.9-1.9-1.91.5-1.5-1.7
Intermittent access day 15 total locomotion0.30.61.9-0.20.6-0.6-1.10.5-0.5-0.5-0.4-0.5-0.6-1.2-0.4-0.8-0.9-0.40.4-0.7-0.7-0.80.8-0.9-0.9-0.91.4-1.4-1.0
Intermittent access total locomotion2.02.43.1-1.6-1.11.1-1.01.7-1.7-1.7-1.7-1.6-1.7-1.4-1.6-1.8-1.7-1.41.4-1.6-1.7-1.61.6-1.7-1.7-1.71.3-1.3-1.5
Intermittent access standard deviation0.40.92.5-0.40.6-0.6-1.00.6-0.7-0.7-0.3-0.6-0.7-1.6-0.7-1.1-0.8-0.90.9-1.0-1.1-0.80.8-0.8-0.8-0.81.6-1.6-1.3
Left kidney weight0.31.29.02.50.6-0.6-3.0-1.31.21.10.70.91.12.00.60.60.80.6-0.60.60.50.7-0.70.60.70.70.1-0.10.5
Right kidney weight0.20.711.41.90.4-0.4-3.4-0.60.50.40.10.20.41.3-0.0-0.10.10.0-0.0-0.2-0.3-0.10.1-0.00.00.00.8-0.8-0.2
Cocaine induced anxiety0.40.52.9-1.0-1.71.71.10.5-0.5-0.4-0.8-0.6-0.40.6-0.20.5-0.1-0.30.30.10.2-0.10.1-0.1-0.1-0.1-1.11.10.7
Post-drug Anxiety1.21.32.50.9-0.00.00.9-1.01.01.00.80.81.11.61.01.51.11.4-1.41.21.21.1-1.11.11.11.1-1.41.41.3
Baseline Anxiety1.82.14.62.12.1-2.1-0.3-1.71.61.62.01.71.60.71.41.01.41.6-1.61.21.01.4-1.41.41.41.4-0.10.10.6
Tail length0.00.21.00.61.0-1.0-0.4-0.40.30.30.60.30.3-0.30.30.30.10.2-0.20.10.00.0-0.00.10.20.20.5-0.5-0.2
Length with tail0.52.15.62.42.2-2.2-1.0-1.81.71.61.91.61.60.91.51.31.31.3-1.31.21.01.2-1.21.31.31.3-0.00.00.7
Length without tail1.44.511.73.43.1-3.1-1.1-2.62.62.52.72.52.41.42.31.82.01.8-1.81.91.81.9-1.91.91.81.8-0.20.21.3
Times rat made contact with spout0.00.00.00.2-0.00.0-0.2-0.10.10.10.10.10.10.20.10.00.10.1-0.10.10.10.1-0.10.10.10.1-0.10.10.1
Lifetime Intake0.20.20.4-0.6-0.40.40.10.5-0.5-0.5-0.5-0.6-0.5-0.5-0.3-0.6-0.5-0.40.4-0.4-0.6-0.50.5-0.5-0.5-0.50.2-0.2-0.3
Liver weight, left0.81.47.82.51.9-1.9-2.8-1.41.31.21.21.11.10.70.90.60.60.3-0.30.50.60.4-0.40.40.50.50.9-0.90.1
Liver weight, right0.20.44.30.70.2-0.2-2.10.1-0.1-0.2-0.4-0.3-0.20.1-0.3-0.2-0.5-0.30.3-0.4-0.4-0.60.6-0.6-0.5-0.50.9-0.9-0.6
Locomotor activity0.10.20.2-0.5-0.20.2-0.10.5-0.5-0.4-0.5-0.4-0.4-0.4-0.4-0.4-0.5-0.10.1-0.5-0.5-0.40.4-0.5-0.5-0.50.3-0.3-0.5
Locomotor testing distance0.71.22.2-1.5-1.41.4-0.11.3-1.3-1.3-1.4-1.4-1.2-0.7-1.2-1.1-1.1-0.70.7-1.1-1.1-1.01.0-1.1-1.2-1.20.4-0.4-0.8
Locomotor testing rearing1.22.43.0-1.5-0.80.8-0.91.6-1.6-1.6-1.6-1.7-1.6-1.6-1.6-1.7-1.7-1.51.5-1.7-1.7-1.71.7-1.7-1.7-1.71.4-1.4-1.6
Locomotion in novel chamber0.40.51.9-1.0-1.41.40.10.8-0.8-0.7-1.0-0.9-0.70.2-0.7-0.2-0.5-0.60.6-0.3-0.2-0.60.6-0.5-0.6-0.6-0.30.30.0
Locomotion in novel chamber post-restriction0.71.12.8-1.2-1.71.7-0.71.1-1.1-1.1-1.4-1.1-1.1-0.2-1.2-0.9-0.9-1.31.3-0.9-1.0-0.90.9-0.9-0.9-0.90.2-0.2-0.4
Fecal boli incidents, locomotor time 10.10.20.40.40.1-0.10.4-0.40.40.40.40.30.40.50.40.60.40.4-0.40.50.60.4-0.40.40.40.4-0.40.40.4
Change in fecal boli incidents, locomotor task0.40.40.90.80.2-0.2-0.2-0.70.70.70.40.60.71.00.70.60.50.7-0.70.70.70.6-0.60.50.50.5-0.70.70.8
Time >=10cm from walls, locomotor time 10.30.40.70.30.2-0.20.8-0.50.50.50.50.50.50.70.50.50.70.5-0.50.60.60.7-0.70.70.70.7-0.80.80.8
Bouts of movement, locomotor time 10.30.31.50.41.2-1.2-0.7-0.20.10.10.40.20.1-0.90.2-0.3-0.2-0.30.3-0.2-0.1-0.30.3-0.2-0.2-0.21.0-1.0-0.4
Total resting periods, locomotor time 10.20.20.70.20.8-0.8-0.7-0.0-0.0-0.00.20.0-0.1-0.80.0-0.3-0.3-0.50.5-0.3-0.2-0.30.3-0.3-0.3-0.30.8-0.8-0.4
Rest time, locomotor task time 10.10.10.6-0.1-0.70.7-0.20.1-0.1-0.2-0.3-0.3-0.10.6-0.20.10.1-0.30.3-0.00.1-0.10.10.00.00.0-0.40.40.3
Distance moved, locomotor task time 10.20.30.7-0.50.1-0.1-0.40.5-0.5-0.5-0.4-0.5-0.6-0.8-0.6-0.6-0.7-0.40.4-0.6-0.7-0.50.5-0.7-0.7-0.70.7-0.8-0.8
Vertical activity count, locomotor time 10.20.40.7-0.6-0.30.3-0.60.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.60.6-0.7-0.8-0.70.7-0.7-0.7-0.70.7-0.7-0.8
Time >=10cm from walls, locomotor time 20.71.02.61.00.1-0.10.4-1.01.00.90.70.81.01.60.91.11.01.1-1.11.01.01.0-1.01.01.01.0-1.21.21.2
Bouts of movement, locomotor time 20.71.12.7-1.3-0.20.2-0.21.1-1.1-1.0-0.9-0.9-1.1-1.6-0.9-1.2-1.2-1.31.3-1.0-0.9-1.01.0-1.2-1.2-1.21.1-1.0-1.0
Total resting periods, locomotor time 20.91.63.5-1.4-0.20.2-0.41.3-1.3-1.2-1.0-1.1-1.3-1.9-1.1-1.5-1.4-1.51.5-1.2-1.1-1.21.2-1.4-1.4-1.41.3-1.3-1.3
Rest time, locomotor task time 20.70.91.2-1.0-0.40.4-0.41.0-1.0-1.0-0.9-1.0-1.0-1.0-1.0-1.1-1.0-1.11.1-1.1-1.0-1.11.1-1.0-1.0-1.00.9-0.9-0.9
Distance moved, locomotor task time 20.40.41.00.5-0.10.10.3-0.60.60.60.50.60.61.00.50.70.80.7-0.70.70.70.7-0.70.70.70.7-0.80.80.7
Vertical activity count, locomotor time 20.30.51.10.6-0.10.10.2-0.60.60.70.50.60.61.00.60.70.70.9-0.90.80.70.7-0.70.70.70.7-0.80.80.8
Light reinforcement 10.10.31.5-0.6-1.21.2-0.40.5-0.5-0.5-0.5-0.7-0.50.2-0.5-0.4-0.3-0.40.4-0.3-0.2-0.30.3-0.3-0.3-0.3-0.10.10.0
Light reinforcement 20.10.21.5-0.7-1.21.20.40.3-0.3-0.3-0.5-0.3-0.30.4-0.20.10.0-0.20.20.00.10.1-0.10.0-0.0-0.0-0.70.70.4
Bone: marrow area0.20.51.51.21.2-1.2-0.8-0.90.80.80.90.80.70.20.70.50.50.4-0.40.50.50.4-0.40.40.50.50.3-0.30.2
Bone: maximum diameter1.01.97.22.42.7-2.7-1.4-1.71.61.61.71.61.50.41.41.00.91.0-1.00.90.90.9-0.90.90.90.90.5-0.50.4
Bone: maximum force1.22.14.52.10.8-0.8-0.6-1.71.71.61.31.51.62.01.41.41.61.4-1.41.41.41.5-1.51.51.51.5-1.01.01.4
Bone: maximum moment1.32.24.52.10.9-0.9-0.5-1.71.71.71.41.61.62.01.41.41.61.5-1.51.41.51.6-1.61.51.51.5-1.11.11.4
Mean time between licks in bursts0.71.72.91.01.2-1.21.7-1.31.31.31.51.41.30.71.41.31.31.4-1.41.31.31.3-1.31.31.31.3-1.01.01.2
Mean num. licks in bursts2.33.74.6-1.7-1.31.3-1.62.0-2.0-2.0-2.0-1.9-2.0-1.7-2.1-2.0-2.1-2.02.0-2.1-2.1-1.91.9-2.1-2.1-2.11.7-1.7-2.0
Cd content in liver0.80.95.7-1.2-2.42.41.20.7-0.6-0.6-1.0-0.8-0.50.9-0.50.10.10.3-0.30.10.10.1-0.10.10.10.1-1.41.30.7
Co content in liver0.30.32.1-0.5-1.51.50.20.4-0.3-0.3-0.7-0.4-0.30.8-0.40.20.10.1-0.10.00.10.1-0.10.00.00.0-0.80.80.3
Cu content in liver0.20.30.8-0.9-0.90.90.30.7-0.6-0.6-0.5-0.6-0.6-0.3-0.6-0.4-0.4-0.50.5-0.5-0.5-0.40.4-0.4-0.3-0.30.0-0.0-0.3
Fe content in liver2.73.34.92.21.9-1.90.4-2.12.12.12.12.12.01.52.01.81.81.8-1.81.81.81.8-1.81.81.81.8-1.11.11.5
K content in liver0.70.71.8-0.90.0-0.0-0.30.8-0.8-0.8-0.6-0.7-0.9-1.3-0.8-0.8-1.0-1.01.0-0.9-0.8-0.90.9-0.9-0.9-0.90.9-0.9-1.0
Mg content in liver3.23.35.5-1.8-0.40.4-1.11.8-1.8-1.8-1.5-1.7-1.9-2.3-1.8-1.9-2.0-2.02.0-1.9-1.9-2.02.0-2.0-1.9-1.91.9-1.9-2.1
Mn content in liver0.50.61.0-0.40.1-0.1-0.90.6-0.7-0.7-0.6-0.6-0.7-0.8-0.7-0.7-0.9-0.90.9-0.8-0.8-0.80.8-0.9-0.9-0.91.0-1.0-1.0
Na content in liver1.81.93.5-0.90.3-0.3-1.31.2-1.2-1.2-1.0-1.0-1.3-1.9-1.3-1.5-1.5-1.71.7-1.6-1.5-1.41.4-1.4-1.5-1.51.8-1.8-1.7
Rb content in liver0.20.30.9-0.30.6-0.6-0.40.3-0.3-0.3-0.1-0.2-0.4-1.0-0.4-0.5-0.6-0.60.6-0.5-0.6-0.50.5-0.5-0.5-0.50.8-0.8-0.8
Se content in liver0.40.51.10.40.1-0.10.8-0.60.60.60.50.50.70.80.71.00.71.0-1.00.80.90.7-0.70.70.60.6-0.90.90.8
Sr content in liver1.31.12.9-1.7-1.61.60.41.3-1.3-1.2-1.4-1.4-1.2-0.7-1.1-0.6-1.1-0.70.7-0.7-0.6-1.11.1-1.1-1.1-1.10.1-0.1-0.6
Zn content in liver3.64.06.1-2.5-1.91.9-0.72.3-2.3-2.3-2.2-2.3-2.2-1.9-2.2-2.0-2.1-2.02.0-2.0-2.0-2.12.1-2.0-2.0-2.01.4-1.4-1.8
Bone: minimum diameter0.81.54.82.21.7-1.7-1.6-1.51.51.41.41.51.31.01.20.91.10.8-0.80.90.81.1-1.11.01.01.00.0-0.00.6
Time in familiar zone, hab. session 11.71.64.6-0.6-0.20.2-2.21.1-1.1-1.1-1.1-1.1-1.2-1.1-1.2-1.3-1.3-1.41.4-1.4-1.3-1.41.4-1.3-1.4-1.41.5-1.5-1.4
Time in novel zone, hab. session 12.12.13.41.10.9-0.91.8-1.51.51.51.51.51.51.01.61.51.51.6-1.61.61.51.5-1.51.51.51.5-1.41.41.5
Total zone transitions, hab. session 10.30.42.3-0.2-0.50.5-1.50.5-0.5-0.5-0.6-0.6-0.6-0.3-0.6-0.7-0.6-0.70.7-0.6-0.6-0.60.6-0.6-0.6-0.60.7-0.7-0.6
Total locomotion distance, hab. session 11.52.12.71.30.4-0.41.1-1.51.51.51.31.51.51.61.51.51.61.5-1.51.61.61.6-1.61.61.61.6-1.51.51.7
Locomotion velocity, hab. session 11.21.72.41.10.2-0.21.0-1.31.31.31.11.31.31.61.31.31.41.3-1.31.41.41.4-1.41.41.41.4-1.51.51.5
Time in familiar zone, hab. session 20.90.92.11.21.5-1.50.4-1.11.11.11.21.21.00.31.10.90.80.8-0.80.90.90.8-0.80.80.80.8-0.20.20.6
Time in novel zone, hab. session 20.60.61.5-1.0-1.21.2-0.31.0-0.9-1.0-1.1-1.0-0.9-0.2-1.0-0.8-0.7-0.70.7-0.8-0.8-0.70.7-0.7-0.7-0.70.2-0.2-0.5
Total zone transitions, hab. session 20.60.81.1-0.7-0.60.6-1.10.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-1.0-0.9-1.01.0-1.0-0.9-1.01.0-1.0-1.0-1.00.9-0.9-0.9
Total locomotion distance, hab. session 20.10.10.20.50.1-0.1-0.3-0.30.30.30.20.30.30.40.30.20.30.2-0.20.30.20.3-0.30.20.30.3-0.10.10.3
Locomotion velocity, hab. session 20.00.00.30.30.0-0.0-0.5-0.10.10.10.00.10.10.10.1-0.10.0-0.10.10.00.00.0-0.0-0.00.00.00.2-0.20.0
Novel to familiar place preference ratio2.32.53.21.50.9-0.91.2-1.61.61.71.51.61.71.61.61.71.71.8-1.81.71.71.7-1.71.71.71.7-1.61.61.7
Novelty place preference1.71.92.41.20.9-0.91.1-1.41.41.41.31.41.41.31.41.41.41.6-1.61.51.41.5-1.51.41.51.5-1.31.31.4
Time in novel zone, NPP test2.62.83.41.71.4-1.41.0-1.81.81.81.71.81.81.51.81.71.71.8-1.81.81.71.7-1.71.71.71.7-1.41.41.6
Total zone transitions, NPP test0.10.10.3-0.1-0.30.3-0.60.3-0.3-0.3-0.3-0.3-0.3-0.1-0.3-0.4-0.3-0.40.4-0.3-0.3-0.30.3-0.3-0.3-0.30.3-0.3-0.2
Total locomotion distance, NPP test0.70.92.10.8-0.30.30.8-0.90.90.90.60.80.91.50.90.91.01.0-1.01.01.11.0-1.01.01.01.0-1.21.21.2
Locomotion velocity, NPP test0.50.71.80.3-0.90.90.9-0.50.50.50.20.40.61.40.50.70.80.7-0.70.80.80.8-0.80.80.80.8-1.31.31.1
Intraocular pressure1.52.13.51.91.8-1.80.3-1.71.61.71.71.71.61.01.41.61.41.7-1.71.41.31.4-1.41.41.41.4-0.60.60.9
Delta distance traveled before/after self-admin0.30.41.0-0.30.4-0.4-0.60.4-0.4-0.4-0.4-0.3-0.5-1.0-0.3-0.4-0.7-0.40.4-0.6-0.5-0.70.7-0.7-0.7-0.71.0-1.0-0.8
Delta ambulatory time before/after self-admin0.10.20.60.20.8-0.8-0.7-0.00.00.0-0.00.2-0.1-0.70.1-0.1-0.3-0.20.2-0.3-0.2-0.30.3-0.3-0.3-0.30.8-0.8-0.4
Parametrial fat weight2.96.825.15.04.8-4.8-4.3-3.13.02.83.12.82.71.12.31.41.61.5-1.51.41.41.5-1.51.41.51.51.5-1.50.3
Pavlov. Cond. lever latency0.10.20.60.20.8-0.80.5-0.30.30.40.50.40.3-0.30.40.40.30.3-0.30.30.40.3-0.30.30.30.3-0.10.10.1
Pavlov. Cond. magazine entry latency0.00.00.2-0.0-0.10.1-0.40.2-0.2-0.2-0.2-0.1-0.2-0.1-0.2-0.2-0.2-0.20.2-0.3-0.3-0.20.2-0.2-0.2-0.20.3-0.3-0.2
Pavlov. Cond. change in total contacts0.30.31.1-0.0-0.10.1-1.00.4-0.4-0.4-0.4-0.4-0.4-0.4-0.5-0.6-0.6-0.60.6-0.6-0.6-0.60.6-0.6-0.6-0.60.8-0.8-0.6
Pavlov. Cond. index score0.10.20.8-0.0-0.10.1-0.90.3-0.3-0.3-0.3-0.3-0.3-0.2-0.4-0.5-0.4-0.40.4-0.4-0.5-0.40.4-0.4-0.4-0.40.5-0.5-0.4
Pavlov. Cond. latency score0.10.10.6-0.1-0.30.3-0.70.3-0.3-0.3-0.4-0.3-0.3-0.1-0.4-0.5-0.4-0.40.4-0.4-0.5-0.40.4-0.4-0.4-0.40.4-0.4-0.4
Pavlov. Cond. lever contacts0.20.20.7-0.1-0.20.2-0.80.3-0.4-0.4-0.4-0.4-0.4-0.2-0.5-0.6-0.4-0.60.6-0.5-0.6-0.50.5-0.5-0.5-0.50.6-0.6-0.5
Pavlov. Cond. magazine entry number0.20.30.60.20.0-0.00.8-0.40.40.40.40.40.50.60.50.60.60.6-0.60.60.60.6-0.60.60.60.6-0.70.70.6
Pavlov. Cond. intertrial magazine entries0.80.93.01.2-0.10.1-0.0-0.90.90.90.60.71.01.70.81.01.01.1-1.11.01.01.0-1.00.91.01.0-1.11.11.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.80.1-0.00.0-0.90.2-0.2-0.2-0.3-0.2-0.3-0.2-0.3-0.4-0.3-0.40.4-0.4-0.4-0.30.3-0.4-0.4-0.40.5-0.5-0.4
Pavlov. Cond. response bias0.30.30.5-0.4-0.40.4-0.60.5-0.5-0.5-0.6-0.5-0.6-0.4-0.6-0.7-0.6-0.60.6-0.6-0.7-0.60.6-0.6-0.6-0.60.6-0.6-0.6
Pavlov. Cond. lever latency1.01.32.5-1.5-1.61.6-0.11.4-1.3-1.3-1.5-1.5-1.2-0.6-1.2-1.0-1.1-0.90.9-1.0-1.0-1.21.2-1.1-1.1-1.10.4-0.4-0.7
Pavlov. Cond. magazine entry latency0.20.21.40.41.2-1.2-0.1-0.30.30.30.50.30.2-0.60.2-0.00.00.2-0.20.0-0.0-0.10.10.00.00.00.6-0.6-0.4
Pavlov. Cond. change in total contacts0.30.61.60.91.2-1.20.2-0.90.90.91.01.00.80.10.80.60.70.6-0.60.60.60.7-0.70.70.70.7-0.10.10.3
Pavlov. Cond. index score0.50.62.31.11.5-1.5-0.1-0.90.90.91.11.00.80.10.80.60.70.6-0.60.60.60.7-0.70.70.70.70.1-0.10.2
Pavlov. Cond. latency score0.40.62.01.01.4-1.4-0.0-0.90.90.91.11.00.80.10.80.50.60.6-0.60.60.60.6-0.60.70.60.60.0-0.00.2
Pavlov. Cond. lever contacts0.60.81.41.21.1-1.1-0.1-1.11.11.01.11.21.00.50.90.80.90.6-0.60.80.81.0-1.00.90.90.9-0.30.30.6
Pavlov. Cond. magazine entry number0.10.10.9-0.4-1.01.00.20.3-0.3-0.3-0.5-0.3-0.20.4-0.20.1-0.1-0.10.10.00.00.1-0.1-0.1-0.1-0.1-0.50.50.3
Pavlov. Cond. intertrial magazine entries0.10.11.10.70.2-0.2-1.0-0.30.30.20.20.20.20.50.20.10.2-0.20.20.10.10.1-0.10.20.20.20.1-0.10.1
Pavlov. Cond. lever-magazine prob. diff.0.30.41.70.91.3-1.3-0.1-0.70.70.70.90.80.7-0.10.60.40.50.4-0.40.40.40.5-0.50.50.50.50.2-0.20.1
Pavlov. Cond. response bias1.01.32.71.51.6-1.60.2-1.41.31.31.51.51.30.51.21.01.20.9-0.91.01.01.2-1.21.21.11.1-0.40.40.7
Time in closed arm before self-admin0.50.61.1-0.5-0.30.3-0.80.7-0.7-0.7-0.7-0.7-0.8-0.7-0.8-0.9-0.8-0.70.7-1.0-1.0-0.80.8-0.8-0.8-0.80.9-0.9-1.0
Time in closed arm after self-admin1.71.92.9-1.6-1.41.4-0.21.6-1.5-1.5-1.7-1.5-1.5-1.0-1.6-1.6-1.3-1.21.2-1.6-1.7-1.31.3-1.3-1.3-1.30.8-0.8-1.4
Time in open arm before self-admin0.40.41.7-0.2-0.50.51.3-0.30.30.40.20.30.40.70.60.50.50.5-0.50.80.80.5-0.50.50.50.5-1.21.21.2
Time in open arm after self-admin1.51.72.61.21.4-1.41.0-1.41.41.41.61.41.40.61.61.41.21.3-1.31.51.51.2-1.21.21.21.2-0.80.81.3
Bone: periosteal estimation0.92.06.12.51.7-1.7-1.4-1.81.71.71.61.71.61.41.41.21.31.2-1.21.21.21.3-1.31.21.21.2-0.20.20.9
Bone: periosteal perimeter0.61.16.01.92.1-2.1-2.4-1.00.90.91.11.00.70.00.60.10.30.1-0.10.10.10.3-0.30.20.30.31.2-1.2-0.4
Bone: post-yield work3.14.55.82.21.0-1.01.2-2.22.22.22.02.12.32.42.22.32.32.3-2.32.32.32.2-2.22.32.32.3-2.02.02.3
Progressive ratio test 1 active lever presses1.21.52.3-1.5-0.70.7-0.21.3-1.3-1.3-1.2-1.2-1.4-1.5-1.1-1.5-1.3-1.31.3-1.3-1.4-1.21.2-1.2-1.2-1.21.0-1.0-1.1
Progressive ratio test 1 breakpoint1.11.42.2-1.5-0.70.7-0.11.3-1.3-1.3-1.2-1.2-1.3-1.4-1.1-1.4-1.2-1.21.2-1.3-1.4-1.21.2-1.2-1.2-1.21.0-1.0-1.1
Progressive ratio test 1 inactive lever presses0.10.10.40.20.7-0.7-0.1-0.20.20.20.00.30.1-0.30.4-0.3-0.20.3-0.3-0.0-0.10.1-0.1-0.2-0.2-0.20.3-0.3-0.0
Progressive ratio test 2 active lever presses0.80.91.7-0.7-0.10.1-1.10.9-0.9-0.9-0.7-0.8-0.9-1.3-0.8-1.1-1.0-1.01.0-1.1-1.1-1.01.0-1.0-1.0-1.01.3-1.3-1.1
Progressive ratio test 2 breakpoint0.70.81.6-0.6-0.00.0-1.10.8-0.8-0.9-0.7-0.8-0.9-1.2-0.7-1.0-0.9-1.01.0-1.0-1.1-0.90.9-0.9-0.9-0.91.3-1.3-1.0
Progressive ratio test 2 inactive lever presses0.40.71.20.80.7-0.70.7-0.90.90.90.81.00.90.71.10.60.81.0-1.00.80.80.9-0.90.80.80.8-0.70.70.9
Incentive Sensitization - Responses0.40.52.00.00.6-0.6-1.40.4-0.4-0.4-0.3-0.4-0.5-1.0-0.4-0.6-0.7-0.50.5-0.6-0.7-0.70.7-0.7-0.7-0.71.3-1.3-0.9
Incentive Sensitization - Breakpoint0.30.41.80.10.7-0.7-1.30.3-0.3-0.3-0.1-0.3-0.3-1.0-0.3-0.5-0.6-0.40.4-0.5-0.6-0.60.6-0.6-0.6-0.61.2-1.2-0.9
Sum of active levers in priming session hrs 5-60.20.21.00.21.0-1.0-0.3-0.00.0-0.00.40.1-0.0-1.00.1-0.0-0.2-0.20.2-0.2-0.0-0.20.2-0.2-0.2-0.20.9-0.9-0.6
Progressive ratio0.30.53.5-0.4-0.40.41.9-0.30.30.40.20.50.30.40.50.50.50.5-0.50.60.70.7-0.70.50.60.6-1.21.20.8
Food seeking constrained by brief footshock0.00.00.3-0.5-0.10.10.50.2-0.1-0.1-0.0-0.0-0.1-0.2-0.10.10.10.1-0.10.0-0.10.1-0.10.10.10.1-0.30.30.1
Seeking ratio, punishment vs. effort1.11.63.2-0.7-0.30.3-1.81.2-1.2-1.2-1.0-1.3-1.2-1.2-1.3-1.2-1.2-1.11.1-1.4-1.6-1.41.4-1.3-1.4-1.41.5-1.5-1.5
Retroperitoneal fat weight4.017.262.77.96.8-6.8-6.4-5.14.94.74.94.74.42.73.82.83.12.7-2.72.72.62.8-2.82.82.82.81.3-1.31.2
Reaction time number correct0.50.92.4-0.50.6-0.6-0.80.7-0.7-0.7-0.3-0.5-0.8-1.5-0.7-1.2-0.9-1.01.0-1.1-1.1-0.90.9-0.8-0.8-0.81.4-1.4-1.2
Reaction time mean minus median0.61.63.6-0.60.3-0.3-1.41.0-1.0-1.1-0.5-1.0-1.1-1.7-1.1-1.5-1.1-1.41.4-1.4-1.5-1.31.3-1.1-1.1-1.11.9-1.9-1.7
Reaction time mean minus median AUC2.46.09.2-1.9-0.50.5-2.02.3-2.3-2.4-1.7-2.2-2.4-3.0-2.5-2.9-2.4-2.82.8-2.8-2.8-2.62.6-2.3-2.4-2.43.0-3.0-3.0
Reaction time num false alarms0.10.10.60.1-0.70.7-0.2-0.10.10.1-0.10.10.10.8-0.10.00.40.1-0.10.10.00.3-0.30.40.40.4-0.50.50.3
Reaction time num false alarms AUC0.10.10.8-0.3-0.90.9-0.50.3-0.3-0.3-0.5-0.3-0.30.3-0.5-0.4-0.1-0.30.3-0.4-0.4-0.10.1-0.1-0.1-0.1-0.10.1-0.1
Reaction time trials correct on left0.50.92.4-0.50.6-0.6-0.80.7-0.7-0.7-0.3-0.5-0.8-1.5-0.7-1.2-0.9-1.01.0-1.1-1.1-0.90.9-0.8-0.8-0.81.4-1.4-1.2
Reaction time trials on left0.51.02.6-0.50.6-0.6-0.90.7-0.7-0.7-0.3-0.6-0.8-1.6-0.7-1.2-0.9-1.01.0-1.1-1.1-1.01.0-0.9-0.9-0.91.5-1.5-1.3
Reaction time mean3.25.18.9-2.0-0.40.4-1.32.2-2.2-2.3-1.7-2.1-2.3-3.0-2.2-2.5-2.3-2.42.4-2.5-2.5-2.52.5-2.2-2.2-2.22.7-2.7-2.7
Reaction time mean AUC3.96.310.8-2.3-0.50.5-1.42.5-2.5-2.5-1.9-2.4-2.5-3.3-2.4-2.8-2.5-2.72.7-2.8-2.8-2.82.8-2.5-2.4-2.42.9-2.9-3.0
Median of all reaction times4.26.09.8-2.4-0.80.8-1.22.5-2.5-2.5-2.0-2.4-2.5-3.1-2.4-2.7-2.5-2.62.6-2.7-2.7-2.72.7-2.5-2.4-2.42.7-2.7-2.8
Reaction time omissions0.81.13.7-0.01.3-1.3-1.40.4-0.5-0.50.0-0.3-0.6-1.8-0.6-1.0-0.9-0.80.8-1.0-1.1-1.01.0-0.8-0.8-0.81.9-1.9-1.5
Reaction time false alarm rate0.30.52.00.4-0.80.80.2-0.40.40.40.10.40.51.40.30.60.70.6-0.60.60.60.7-0.70.70.70.7-1.11.10.9
Reaction time premature initiation rate0.10.20.8-0.2-0.90.9-0.60.4-0.4-0.4-0.5-0.4-0.40.2-0.5-0.4-0.2-0.40.4-0.5-0.4-0.20.2-0.2-0.2-0.20.1-0.1-0.3
Reaction time premature initiations0.40.61.1-0.5-0.50.5-1.00.7-0.7-0.8-0.6-0.7-0.8-0.7-0.9-1.1-0.6-1.01.0-1.0-1.0-0.80.8-0.7-0.6-0.60.9-0.9-1.0
Std. dev. reaction times1.22.35.5-0.60.5-0.5-1.81.1-1.2-1.3-0.6-1.1-1.3-2.1-1.4-1.8-1.3-1.61.6-1.7-1.8-1.61.6-1.3-1.2-1.22.3-2.3-2.1
Reaction time trials completed0.51.02.6-0.50.6-0.6-0.90.7-0.7-0.7-0.3-0.6-0.8-1.6-0.7-1.2-0.9-1.01.0-1.1-1.1-1.01.0-0.9-0.9-0.91.5-1.5-1.3
Reaction time trials AUC0.50.92.3-0.40.6-0.6-1.00.6-0.7-0.7-0.3-0.5-0.7-1.5-0.7-1.1-0.9-1.01.0-1.1-1.1-0.90.9-0.8-0.8-0.81.5-1.5-1.2
Run reversals in cocaine runway, females0.10.10.30.30.5-0.5-0.2-0.20.20.20.30.30.2-0.20.20.00.1-0.00.00.00.20.1-0.10.10.20.20.2-0.2-0.1
Run reversals in cocaine runway, males0.90.91.4-1.1-1.11.1-0.41.1-1.1-1.1-1.2-1.2-1.1-0.7-1.2-1.0-1.0-0.80.8-1.0-1.0-1.01.0-1.0-1.0-1.00.5-0.5-0.9
Latency to leave start box in cocaine runway1.01.23.6-1.20.4-0.4-0.11.0-1.0-1.0-0.7-0.8-1.1-1.9-1.0-1.3-1.1-1.21.2-1.3-1.2-1.01.0-1.0-0.9-0.91.3-1.3-1.4
Latency to leave start box in cocaine runway, F0.30.41.4-0.50.7-0.7-0.30.4-0.5-0.4-0.2-0.3-0.5-1.2-0.4-0.6-0.6-0.50.5-0.6-0.5-0.60.6-0.5-0.5-0.50.9-0.9-0.8
Latency to leave start box in cocaine runway, M1.31.22.0-1.2-0.40.4-0.21.1-1.1-1.1-0.9-1.0-1.2-1.4-1.2-1.4-1.1-1.11.1-1.3-1.4-1.01.0-1.0-1.0-1.01.1-1.1-1.3
Std. dev. time between licks in bursts1.92.64.50.90.2-0.22.1-1.41.41.51.31.41.51.61.61.71.71.7-1.71.81.81.8-1.81.71.71.7-2.02.01.9
Total sessions with >9 infusions0.10.10.5-0.5-0.70.70.40.3-0.3-0.3-0.5-0.2-0.30.1-0.2-0.5-0.2-0.20.2-0.3-0.4-0.10.1-0.2-0.2-0.2-0.20.20.0
Short access day 1 total inactive lever presses1.82.43.61.20.8-0.81.9-1.51.51.61.31.71.51.51.71.11.61.8-1.81.41.41.8-1.81.61.61.6-1.71.71.6
Short access day 10 total inactive lever presses0.00.10.30.60.6-0.6-0.6-0.20.20.20.10.20.20.10.0-0.2-0.00.4-0.4-0.1-0.10.0-0.0-0.0-0.0-0.00.3-0.3-0.3
Short access day 1 total infusions0.10.20.4-0.5-0.40.40.10.5-0.5-0.4-0.6-0.3-0.5-0.3-0.4-0.6-0.4-0.30.3-0.7-0.7-0.40.4-0.4-0.4-0.40.2-0.2-0.4
Short access day 10 total infusions0.91.22.9-1.7-1.51.50.71.3-1.3-1.2-1.3-1.2-1.2-0.8-1.1-1.2-0.9-1.01.0-1.1-1.2-0.90.9-0.9-0.9-0.90.2-0.2-0.7
Short access total infusions0.30.31.1-1.0-1.11.10.80.7-0.6-0.6-0.7-0.6-0.6-0.1-0.5-0.6-0.3-0.40.4-0.5-0.6-0.30.3-0.3-0.3-0.3-0.20.2-0.2
Short access day 1 locomotion0.70.91.9-0.9-0.20.2-0.40.9-0.9-0.9-0.8-0.6-1.0-1.2-0.9-1.4-0.8-1.31.3-1.2-1.1-0.80.8-0.8-0.8-0.81.1-1.1-1.2
Short access day 10 total locomotion1.12.13.6-1.5-1.01.0-0.51.6-1.6-1.5-1.6-1.4-1.6-1.4-1.7-1.9-1.4-1.31.3-1.7-1.7-1.41.4-1.4-1.4-1.41.2-1.2-1.7
Short access total locomotion2.02.43.9-2.0-1.71.7-0.11.8-1.8-1.7-1.8-1.6-1.8-1.2-1.8-2.0-1.4-1.61.6-1.7-1.8-1.41.4-1.4-1.4-1.40.8-0.8-1.3
One hour access (0.3 mA shock)0.10.21.10.31.1-1.1-0.0-0.30.30.30.50.30.3-0.70.60.00.00.3-0.30.20.1-0.00.00.10.10.10.4-0.4-0.0
Compulsive drug intake0.50.61.91.11.4-1.4-0.0-0.90.80.80.90.80.80.30.80.60.61.3-1.30.50.50.4-0.40.60.60.6-0.00.00.2
One hour access (shock baseline)0.20.30.8-0.9-0.50.50.30.6-0.6-0.6-0.5-0.7-0.6-0.7-0.4-0.5-0.6-0.60.6-0.3-0.5-0.50.5-0.6-0.6-0.60.3-0.3-0.3
Social response proportion0.80.91.8-0.5-0.70.7-1.30.9-0.9-0.9-1.2-1.0-0.9-0.4-1.1-1.0-1.1-0.70.7-1.0-0.9-1.01.0-1.1-1.1-1.10.9-0.9-1.0
Social responses0.20.31.41.20.8-0.8-1.1-0.60.60.60.40.50.50.40.40.20.20.6-0.60.30.30.2-0.20.10.10.10.3-0.30.0
Social time2.83.85.1-1.5-0.40.4-1.41.9-1.9-1.9-1.8-1.9-1.9-2.2-1.9-2.2-2.2-1.91.9-2.1-2.1-2.22.2-2.2-2.3-2.32.2-2.2-2.2
Soleus weight3.811.123.4-1.50.2-0.2-4.82.6-2.7-2.8-2.5-2.7-2.9-3.6-3.0-3.6-3.6-3.53.5-3.5-3.5-3.63.6-3.7-3.7-3.74.4-4.4-4.0
Bone: stiffness1.62.64.22.00.8-0.80.1-1.81.81.71.51.71.72.11.61.61.81.7-1.71.61.61.7-1.71.71.81.8-1.41.41.7
Tibialis anterior weight0.51.96.00.11.4-1.4-2.40.5-0.6-0.6-0.3-0.5-0.7-1.9-0.6-1.3-1.4-1.31.3-1.2-1.3-1.31.3-1.4-1.4-1.42.3-2.3-1.6
Time to tail flick, vehicle, before self-admin1.31.32.21.00.2-0.20.6-1.11.21.20.91.11.11.51.21.21.21.2-1.21.31.31.2-1.21.11.11.1-1.31.31.4
Time to tail flick, vehicle, after self-admin0.10.10.30.50.3-0.3-0.4-0.40.40.40.30.20.40.40.40.60.20.5-0.50.40.50.1-0.10.20.20.2-0.20.20.3
Time to tail flick, test, before self-admin2.72.84.3-2.1-1.91.9-0.71.9-1.9-1.8-2.0-1.7-1.9-1.2-1.9-1.8-1.5-2.02.0-1.8-1.8-1.51.5-1.5-1.5-1.50.9-0.9-1.4
Time to tail flick, test, after self-admin1.11.22.20.90.9-0.91.3-1.11.11.11.11.01.10.71.11.21.01.5-1.51.11.11.0-1.01.01.01.0-0.90.91.0
Delta time to tail flick, vehicle, before/after SA0.30.31.10.31.0-1.0-1.00.0-0.1-0.10.2-0.1-0.1-0.8-0.00.0-0.3-0.40.4-0.3-0.2-0.40.4-0.3-0.3-0.31.0-1.0-0.6
Delta time to tail flick, test, before/after SA2.42.54.91.61.3-1.31.6-1.61.61.61.61.41.71.41.71.81.42.2-2.21.81.71.4-1.41.41.41.4-1.31.31.5
Tibia length0.00.10.40.5-0.10.1-0.6-0.30.30.30.20.30.30.60.40.30.30.3-0.30.30.30.2-0.20.30.30.3-0.30.30.4
Ambulatory time before self-admin1.82.75.8-2.2-2.42.4-0.12.0-1.9-1.9-1.8-2.0-1.8-0.9-2.0-1.8-1.4-1.81.8-1.6-1.6-1.41.4-1.4-1.4-1.40.5-0.5-1.2
Ambulatory time after self-admin2.12.53.6-1.9-1.41.4-0.61.8-1.7-1.7-1.8-1.6-1.8-1.5-1.6-1.6-1.6-1.71.7-1.6-1.5-1.61.6-1.6-1.6-1.61.1-1.1-1.4
Bone: tissue strength0.10.10.50.10.2-0.20.7-0.30.30.30.40.30.30.20.30.50.40.4-0.40.40.50.4-0.40.40.40.4-0.40.40.3
Total heroin consumption0.60.72.91.31.7-1.7-1.6-0.70.70.61.00.80.5-0.40.40.30.4-0.70.7-0.10.20.3-0.30.40.40.41.1-1.1-0.5
Bone: trabecular number2.33.87.12.72.2-2.2-0.0-2.32.32.32.32.32.21.62.11.82.01.8-1.81.91.82.0-2.01.91.91.9-0.90.91.6
Bone: trabecular spacing0.20.21.1-1.0-0.60.61.10.6-0.5-0.5-0.3-0.4-0.5-0.5-0.4-0.3-0.2-0.30.3-0.3-0.3-0.20.2-0.1-0.1-0.1-0.20.2-0.2
Bone: trabecular thickness1.01.24.62.12.0-2.0-1.8-1.41.31.31.21.21.20.61.10.70.60.7-0.70.70.70.6-0.60.50.60.60.5-0.50.3
Bone: trabecular tissue density2.13.15.4-2.3-1.51.5-0.02.1-2.0-2.0-1.9-2.0-2.0-1.8-1.9-1.6-1.9-1.71.7-1.7-1.6-1.91.9-1.8-1.8-1.81.1-1.1-1.6
Water consumed over 24 hours0.10.20.3-0.6-0.50.5-0.00.5-0.5-0.5-0.5-0.5-0.5-0.2-0.5-0.4-0.4-0.50.5-0.4-0.4-0.40.4-0.4-0.4-0.40.2-0.2-0.3
Number of responses in last shaping day0.30.30.7-0.6-0.50.5-0.20.6-0.6-0.6-0.8-0.6-0.6-0.5-0.5-0.4-0.8-0.60.6-0.5-0.6-0.50.5-0.8-0.8-0.80.4-0.4-0.4