Hub : Genes

Shisal1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_039080314.2 0.06 0.04 1.3e-09 0.08 0.09 0.08 0.09 2.6e-09 2.9e-10 2.5e-09 3.4e-10
2 BLA alternative TSS XM_017595274.3 0.06 0.04 2.4e-03 0.01 0.01 0.01 0.01 1.5e-01 6.0e-02 9.1e-02 1.0e-01
3 BLA isoform ratio XM_017595274.3 0.08 0.06 2.7e-04 0.02 0.04 0.03 0.02 2.0e-02 6.0e-03 8.3e-03 1.8e-02
4 BLA alternative TSS XM_039080314.2 0.07 0.05 1.3e-03 0 0.02 0.01 0.01 2.5e-01 4.8e-02 7.1e-02 1.3e-01
5 BLA isoform ratio XM_039080314.2 0.08 0.05 4.7e-04 0.02 0.03 0.01 0.02 3.3e-02 1.7e-02 5.5e-02 3.6e-02
6 PL isoform ratio XM_017595274.3 0.06 0.04 6.5e-09 0.08 0.08 0.08 0.08 6.1e-09 1.7e-09 1.2e-08 4.1e-09
7 NAcc mRNA stability Shisal1 0.06 0.03 2.0e-12 0.07 0.08 0.07 0.07 7.6e-11 1.5e-11 3.5e-11 3.3e-11
8 PL alternative TSS XM_017595274.3 0.06 0.04 3.3e-09 0.08 0.09 0.07 0.08 1.9e-09 1.0e-09 1.6e-08 3.8e-09
9 BLA mRNA stability Shisal1 0.31 0.15 2.4e-12 0.16 0.14 0.15 0.15 7.0e-09 8.3e-08 3.0e-08 2.6e-08
10 PL mRNA stability Shisal1 0.16 0.07 0.0e+00 0.13 0.2 0.18 0.18 4.1e-14 7.0e-21 1.7e-19 1.4e-19
11 PL alternative TSS XM_039080314.2 0.06 0.03 9.3e-10 0.08 0.09 0.08 0.1 2.6e-09 3.2e-10 4.0e-09 1.5e-10
12 NAcc gene expression Shisal1 0.02 0.02 1.7e-04 0.03 0.02 0.01 0.02 8.0e-05 5.7e-04 3.4e-03 3.5e-04
13 PL intron excision ratio chr7_117430075_117455025 0.03 0.03 4.1e-04 0.03 0.03 0.03 0.03 1.6e-04 5.9e-04 2.3e-04 3.4e-04
14 pVTA gene expression Shisal1 0.11 0.09 4.2e-04 0.03 0.03 0.02 0.03 3.0e-03 1.4e-03 8.6e-03 1.9e-03
15 Brain gene expression Shisal1 0.25 0.07 0.0e+00 0.14 0.18 0.2 0.21 9.3e-13 6.5e-17 2.9e-18 3.7e-19
16 pVTA mRNA stability Shisal1 0.1 0.09 8.0e-03 0.01 0.02 0.01 0.02 1.9e-02 5.4e-03 8.1e-02 9.3e-03
17 LHb gene expression Shisal1 0.24 0.13 1.2e-04 0.08 0.15 0.13 0.13 5.5e-03 1.9e-04 6.5e-04 6.5e-04
18 IL mRNA stability Shisal1 0.22 0.13 9.3e-03 0.03 0.02 0.06 0.04 6.3e-02 1.1e-01 1.3e-02 4.7e-02
19 Brain mRNA stability Shisal1 0.16 0.08 1.7e-10 0.09 0.11 0.11 0.11 1.6e-08 1.2e-10 1.6e-10 2.3e-10
20 PL gene expression Shisal1 0.14 0.08 8.5e-11 0.09 0.09 0.08 0.09 6.5e-10 2.6e-10 1.0e-08 7.5e-10
21 IC gene expression Shisal1 0.14 0.09 3.6e-03 0.08 0.04 0.05 0.05 2.3e-04 6.3e-03 3.7e-03 3.5e-03
22 Liver gene expression Shisal1 0.4 0.13 0.0e+00 0.33 0.26 0.33 0.33 5.2e-37 2.4e-29 3.0e-37 4.5e-37
23 pVTA intron excision ratio chr7_117430075_117491440 0.14 0.11 1.2e-03 0.04 0.04 0.04 0.03 3.8e-04 3.2e-04 5.6e-04 1.0e-03
24 BLA gene expression Shisal1 0.53 0.24 1.8e-10 0.09 0.2 0.18 0.19 1.2e-05 1.2e-10 4.3e-10 1.6e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.30.51.80.8-1.0-1.00.90.9-0.8-0.8-0.8-0.5-0.70.60.4-0.30.40.6-1.3-0.7-0.2-0.70.60.4-0.1-0.60.2
Area under the delay curve1.72.03.51.5-1.6-1.61.71.7-1.5-1.7-1.4-1.4-1.81.61.4-1.61.91.6-0.8-0.8-0.6-1.71.51.5-0.20.10.8
BMI with tail1.34.47.2-2.62.52.5-2.4-2.42.62.42.62.42.0-2.5-2.32.5-1.4-1.72.72.41.11.4-1.4-1.31.20.8-0.1
BMI without tail0.31.01.4-1.21.11.1-1.1-1.11.11.21.11.01.2-0.9-1.01.0-0.9-1.10.90.70.51.1-1.2-1.2-0.1-0.5-0.7
Body weight1.14.87.2-2.62.72.6-2.6-2.62.62.52.62.42.2-2.6-2.32.7-1.8-1.92.72.31.51.7-1.6-1.21.21.0-0.2
Weight adjusted by age0.60.91.8-0.91.01.0-1.1-1.10.91.00.91.01.1-0.7-0.70.7-0.8-1.31.30.41.21.0-1.1-1.3-0.30.1-0.9
Bone surface0.10.10.50.4-0.5-0.50.50.5-0.3-0.4-0.3-0.0-0.40.40.3-0.30.30.3-0.7-0.2-0.4-0.50.50.40.2-0.20.3
Bone volume0.10.11.00.4-0.5-0.50.50.5-0.3-0.3-0.4-0.0-0.20.40.2-0.20.10.1-1.0-0.4-0.0-0.30.30.20.1-0.50.1
Breakpoint value in progressive ratio session0.20.31.0-0.50.50.5-0.5-0.50.50.60.50.50.5-0.5-0.50.5-0.4-0.50.80.31.00.3-0.5-0.30.10.2-0.2
Number of licking bursts0.40.72.00.9-0.9-0.90.80.8-0.9-0.8-1.0-1.1-0.40.81.0-1.00.20.4-1.4-1.1-0.10.1-0.00.1-1.1-1.1-0.6
Context. condit. distance diff. score2.93.55.3-2.32.22.2-2.2-2.22.32.22.32.02.0-2.2-2.12.0-1.8-1.81.42.01.91.5-1.5-1.11.20.3-0.1
Locomotion velocity, session 11.71.83.0-1.51.61.6-1.5-1.61.51.51.51.71.3-1.2-1.61.3-1.5-1.31.21.31.50.8-0.8-0.71.10.90.3
Locomotion distance, session 10.10.10.40.2-0.2-0.20.30.2-0.2-0.3-0.2-0.0-0.30.10.10.1-0.10.3-0.6-0.0-0.1-0.40.40.40.50.40.6
Locomotion velocity, session 24.14.77.0-2.32.42.4-2.5-2.52.32.52.22.22.6-1.8-2.11.9-2.4-2.62.21.12.52.3-2.5-2.5-0.1-0.2-1.5
Locomotion distance, session 20.20.31.20.3-0.3-0.30.30.3-0.2-0.4-0.2-0.0-0.60.00.10.10.60.60.40.2-0.3-1.00.90.70.81.11.0
Locomotion velocity, session 32.42.74.7-1.71.81.8-1.9-1.91.61.91.61.62.1-1.2-1.61.1-2.2-1.91.10.71.92.0-2.0-2.0-0.2-0.3-1.2
Locomotion distance, session 30.50.52.30.3-0.1-0.1-0.1-0.0-0.30.0-0.4-0.40.40.70.4-0.7-0.6-0.5-0.3-1.10.61.0-0.9-1.1-1.5-1.1-1.4
Stereotopy head waving bouts, day 31.92.24.0-1.71.71.7-1.6-1.61.81.71.82.01.4-1.5-1.91.6-1.2-1.51.91.61.30.6-0.8-0.81.30.90.2
Stereotopy head waving duration, day 34.35.17.7-2.72.62.6-2.6-2.62.72.62.72.82.4-2.5-2.72.6-2.2-2.31.92.22.11.6-1.7-1.51.40.6-0.1
Locomotion velocity, session 70.50.61.3-0.70.90.9-1.0-0.90.70.80.60.40.9-0.6-0.40.6-0.9-0.91.00.20.71.1-1.0-0.8-0.5-0.0-0.8
Locomotion distance, session 70.10.10.20.4-0.3-0.30.30.3-0.4-0.3-0.4-0.4-0.30.30.4-0.40.30.30.2-0.4-0.1-0.20.20.2-0.30.2-0.1
Stereotopy head waving bouts, day 74.65.27.7-2.42.52.5-2.6-2.62.42.62.32.32.7-2.1-2.12.3-2.8-2.71.41.32.62.6-2.6-2.3-0.0-0.4-1.3
Stereotopy head waving duration, day 73.03.65.9-2.02.02.0-2.1-2.11.92.11.81.72.3-1.6-1.61.8-2.3-2.30.90.92.42.4-2.4-2.2-0.4-0.9-1.5
Locomotion velocity, session 88.19.814.1-3.73.73.8-3.7-3.73.73.63.63.53.2-3.5-3.63.5-3.0-2.83.23.13.02.3-2.3-1.92.01.6-0.0
Locomotion distance, session 81.82.73.7-1.91.91.9-1.9-1.91.91.91.81.71.7-1.9-1.81.8-1.6-1.81.51.41.91.4-1.4-1.30.70.4-0.3
Degree of sensitization distance0.91.03.8-0.80.60.6-0.4-0.40.80.41.01.0-0.1-1.1-0.91.00.40.31.21.6-0.1-0.90.80.92.01.61.6
Degree of sensitization stereotypy3.23.55.7-1.92.02.0-2.1-2.11.92.11.81.72.3-1.8-1.62.0-2.4-2.20.70.92.22.4-2.3-2.1-0.4-0.8-1.4
Conditioned locomotion0.30.30.70.5-0.6-0.60.50.5-0.6-0.6-0.6-0.7-0.40.60.8-0.60.50.4-0.7-0.5-0.7-0.10.20.3-0.6-0.6-0.2
Cocaine response after cond. corrected0.30.31.80.0-0.1-0.1-0.1-0.1-0.10.1-0.1-0.20.50.10.2-0.1-0.8-0.5-1.1-0.60.30.8-0.9-0.7-0.9-1.4-0.9
Cocaine response after cond. not corrected0.60.73.50.1-0.1-0.1-0.1-0.1-0.10.2-0.3-0.30.70.20.4-0.1-1.1-0.7-1.5-1.00.41.3-1.3-1.0-1.4-1.9-1.4
Cocaine response before conditioning0.20.20.50.6-0.5-0.50.50.5-0.6-0.5-0.6-0.6-0.30.40.5-0.30.20.5-0.7-0.6-0.5-0.00.10.1-0.6-0.4-0.3
Saline control response0.30.41.9-0.20.10.1-0.2-0.20.10.30.00.10.7-0.2-0.30.4-0.9-0.7-1.0-0.50.60.9-0.9-1.0-0.8-1.4-1.0
Bone: connectivity density0.10.10.60.4-0.5-0.50.50.5-0.4-0.4-0.4-0.2-0.30.40.2-0.00.20.3-0.8-0.40.0-0.40.30.1-0.1-0.40.1
Bone: cortical apparent density1.31.72.81.4-1.5-1.51.61.5-1.4-1.5-1.3-1.2-1.61.31.3-1.11.71.2-0.6-0.8-1.4-1.71.61.40.10.30.8
Bone: cortical area0.40.61.1-0.90.90.9-1.0-0.90.90.90.80.81.0-0.6-0.50.4-1.0-0.80.30.60.81.0-0.9-0.80.0-0.3-0.5
Bone: cortical porosity0.10.10.4-0.10.10.1-0.1-0.10.10.10.1-0.10.30.10.2-0.3-0.2-0.3-0.1-0.10.30.5-0.5-0.5-0.5-0.6-0.6
Bone: cortical porosity0.30.30.6-0.60.60.6-0.6-0.60.60.60.60.40.7-0.5-0.30.1-0.6-0.60.20.30.60.7-0.8-0.7-0.2-0.5-0.5
Bone: cortical thickness0.40.61.30.6-0.6-0.60.70.7-0.6-0.7-0.5-0.5-0.90.60.6-0.80.81.1-0.50.0-1.0-1.11.11.10.70.61.0
Bone: cortical thickness0.30.31.3-0.1-0.0-0.00.20.10.1-0.10.20.2-0.5-0.3-0.20.10.60.70.10.8-0.1-0.90.80.91.10.71.1
Bone: cortical tissue density1.01.42.41.2-1.3-1.31.41.4-1.2-1.3-1.1-1.0-1.51.11.1-0.91.51.1-0.4-0.6-1.3-1.61.51.30.20.40.8
Condit. Reinf. active minus inactive responses1.82.03.01.5-1.5-1.51.51.5-1.5-1.6-1.5-1.6-1.71.41.7-1.71.71.7-0.7-0.9-1.7-1.51.51.4-0.30.40.7
Condit. Reinf. active-inactive response ratio1.11.12.11.1-1.1-1.11.21.2-1.1-1.2-1.0-1.2-1.30.71.3-0.91.31.4-1.1-0.4-1.4-1.11.11.1-0.1-0.10.6
Condit. Reinf. active responses1.92.44.81.8-1.7-1.71.71.7-1.8-1.8-1.8-1.8-1.71.81.9-2.21.71.6-0.7-1.5-1.5-1.21.31.0-0.90.00.2
Condit. Reinf. inactive responses0.50.61.91.0-0.8-0.90.80.8-1.0-0.8-1.0-0.9-0.81.20.9-1.40.70.60.1-1.1-0.5-0.50.50.2-0.80.1-0.2
Incentive salience index mean1.82.33.81.7-1.6-1.61.61.6-1.7-1.7-1.7-1.7-1.71.61.8-2.01.61.7-0.7-1.2-1.7-1.41.51.3-0.50.50.6
Condit. Reinf. lever presses0.60.81.91.2-0.9-0.90.90.9-1.1-1.0-1.1-1.0-1.01.11.1-1.40.70.8-0.2-1.1-1.0-0.70.80.7-0.50.60.3
Condit. Reinf. active minus inactive responses0.40.53.10.00.10.10.00.00.0-0.10.10.2-0.5-0.2-0.20.00.50.60.70.7-0.5-0.91.01.11.31.81.4
Condit. Reinf. active-inactive response ratio0.10.20.90.1-0.0-0.00.10.1-0.1-0.2-0.10.1-0.3-0.1-0.0-0.20.00.4-0.20.3-0.0-0.50.60.70.81.00.9
Condit. Reinf. active responses0.81.14.3-1.01.11.1-0.9-0.91.00.81.11.10.2-1.0-1.20.9-0.1-0.11.71.6-0.1-0.30.50.51.82.11.3
Condit. Reinf. inactive responses1.11.44.1-1.31.31.3-1.2-1.21.31.11.41.30.6-1.1-1.51.2-0.3-0.42.01.70.1-0.00.10.01.61.70.9
Condit. Reinf. lever presses0.40.63.7-0.70.90.9-0.9-0.90.70.70.70.80.4-0.5-0.70.2-0.3-0.61.90.7-0.00.1-0.1-0.10.71.60.4
Condit. Reinf. lever reinforcers received0.50.74.1-0.50.60.7-0.5-0.50.60.40.60.7-0.1-0.5-0.80.40.20.21.51.2-0.4-0.60.80.71.52.01.3
Conditioned reinforcement - actives0.00.10.20.2-0.2-0.20.30.3-0.1-0.2-0.1-0.2-0.30.0-0.20.10.40.3-0.00.1-0.3-0.50.40.30.40.20.3
Conditioned reinforcement - inactives0.20.31.3-0.50.50.5-0.4-0.40.60.40.60.80.2-0.8-0.70.8-0.4-0.20.10.80.5-0.20.30.11.10.70.8
Conditioned locomotion1.41.83.4-1.31.21.2-1.4-1.41.31.51.21.11.7-1.3-1.51.4-1.9-1.80.40.31.71.5-1.6-1.8-0.1-0.8-1.1
Patch foraging indifference point 0 sec0.10.10.60.4-0.4-0.40.40.4-0.4-0.4-0.4-0.3-0.20.00.20.20.00.2-0.7-0.40.0-0.20.20.3-0.1-0.1-0.0
Patch foraging indifference point AUC0.40.61.40.6-0.6-0.60.70.7-0.6-0.7-0.5-0.6-1.00.50.4-0.40.91.0-0.10.0-1.1-1.11.21.10.61.01.0
Delay disc. indifference point, 0s delay0.30.30.8-0.60.50.4-0.5-0.50.60.60.60.50.6-0.3-0.30.3-0.4-0.90.40.20.90.6-0.9-0.6-0.4-0.8-0.7
Delay disc. indifference point, 16s delay1.92.13.61.6-1.7-1.71.81.7-1.6-1.7-1.5-1.6-1.81.61.4-1.51.91.6-0.7-1.1-0.6-1.71.41.4-0.40.10.5
Delay disc. indifference point, 2s delay0.70.81.30.9-1.0-1.01.11.1-0.9-1.0-0.8-0.8-1.10.90.7-1.01.11.1-0.8-0.4-0.2-1.11.00.90.1-0.00.7
Delay disc. indifference point, 24s delay0.70.81.90.8-0.7-0.70.80.8-0.8-0.9-0.8-0.9-1.10.90.8-0.91.21.10.3-0.2-0.7-1.11.11.40.21.10.8
Delay disc. indifference point, 4s delay0.70.72.20.5-0.8-0.80.90.9-0.4-0.8-0.3-0.2-1.10.20.2-0.41.11.1-0.70.30.3-1.51.21.21.00.31.3
Delay disc. indifference point, 8s delay2.32.75.31.8-1.8-1.81.91.9-1.8-1.9-1.7-1.8-2.01.91.8-2.02.31.7-0.5-1.1-1.2-1.71.71.6-0.60.20.5
Indifference point function ln k1.11.83.3-1.31.31.3-1.5-1.41.31.51.21.21.7-1.0-1.11.0-1.7-1.80.60.31.61.8-1.8-1.7-0.5-0.9-1.4
Indifference point function log k1.11.83.3-1.31.31.3-1.5-1.41.31.51.21.21.7-1.0-1.11.0-1.7-1.80.60.31.61.8-1.8-1.7-0.5-0.9-1.4
Patch foraging total patch changes 0 sec0.10.20.90.6-0.6-0.50.50.5-0.6-0.5-0.6-0.5-0.20.20.4-0.00.00.2-0.9-0.70.0-0.10.10.3-0.3-0.4-0.2
Patch foraging total patch changes 12 sec0.20.31.3-0.10.10.1-0.0-0.00.1-0.10.20.1-0.3-0.4-0.30.50.30.50.30.7-0.6-0.60.60.91.01.11.0
Patch foraging total patch changes 18 sec0.40.63.00.9-1.0-1.01.01.0-0.8-0.9-0.9-0.6-0.80.30.5-0.10.30.9-1.7-0.6-0.5-0.80.90.90.3-0.20.7
Patch foraging total patch changes 24 sec0.30.41.1-0.20.30.3-0.5-0.50.20.50.10.30.8-0.2-0.20.4-1.0-1.1-0.1-0.50.81.0-1.0-1.0-0.8-0.7-1.0
Patch foraging total patch changes 6 sec0.40.61.90.7-0.7-0.70.80.8-0.7-0.8-0.6-0.6-0.90.20.3-0.00.61.1-1.1-0.0-1.0-1.01.11.40.80.41.0
Patch foraging time to switch 0 sec0.10.21.3-0.10.10.1-0.2-0.20.20.30.10.20.40.2-0.40.0-0.2-0.60.6-0.31.10.4-0.6-0.9-0.7-0.5-0.8
Patch foraging water rate 0 sec0.10.30.9-0.60.70.7-0.7-0.70.60.60.60.40.6-1.0-0.30.7-0.7-0.40.10.6-0.00.6-0.4-0.00.30.20.1
Patch foraging water rate 12 sec1.02.15.2-0.90.90.9-1.2-1.10.81.20.70.61.8-1.0-0.60.9-2.1-1.9-0.6-0.51.52.3-2.2-2.1-1.5-2.0-2.1
Patch foraging water rate 18 sec0.00.00.20.1-0.1-0.10.10.1-0.1-0.1-0.1-0.00.00.10.2-0.1-0.1-0.0-0.5-0.1-0.40.10.00.10.0-0.1-0.0
Patch foraging water rate 24 sec1.31.83.0-1.51.51.5-1.5-1.51.51.61.51.41.6-1.3-1.41.1-1.6-1.60.90.91.71.4-1.5-1.30.2-0.3-0.7
Patch foraging water rate 6 sec0.20.30.70.5-0.5-0.50.40.4-0.6-0.4-0.6-0.6-0.20.50.8-0.80.0-0.0-0.7-0.8-0.80.2-0.0-0.1-0.8-0.6-0.5
Seeking ratio, delayed vs. immediate footshock1.51.83.71.6-1.5-1.51.41.4-1.6-1.4-1.7-1.9-1.11.51.7-1.51.00.9-1.1-1.8-1.2-0.30.50.2-1.7-1.1-0.8
Distance traveled before self-admin0.30.40.60.7-0.7-0.70.70.7-0.7-0.7-0.7-0.7-0.70.60.5-0.40.50.8-0.7-0.5-0.7-0.60.70.60.10.20.5
Distance traveled after self-admin0.10.10.6-0.10.10.1-0.2-0.20.10.20.10.40.3-0.2-0.40.3-0.8-0.4-0.6-0.10.40.2-0.0-0.20.3-0.10.2
Extensor digitorum longus weight0.31.32.7-1.11.21.1-1.3-1.31.01.31.00.81.4-0.8-0.81.0-1.2-1.51.20.21.21.5-1.6-1.6-0.8-0.5-1.3
Bone: elastic displacement1.31.53.4-1.31.31.3-1.4-1.41.31.41.21.21.6-1.1-1.20.9-1.9-1.30.20.61.51.6-1.6-1.2-0.1-0.5-0.8
Bone: elastic work4.86.39.4-2.92.92.9-3.0-3.02.83.02.82.73.0-2.6-2.72.4-3.1-2.61.61.82.62.6-2.6-2.20.7-0.0-0.9
Bone: endosteal estimation3.47.411.2-3.03.03.0-3.2-3.22.93.22.82.73.3-2.6-2.42.5-3.2-3.22.01.62.93.2-3.2-2.9-0.1-0.7-1.8
Bone: endosteal perimeter3.06.313.1-2.42.52.5-2.8-2.82.32.72.11.83.2-1.9-1.61.8-3.2-3.21.30.62.93.6-3.5-3.4-1.3-1.6-2.7
Epididymis fat weight0.31.13.3-1.31.21.2-1.1-1.11.31.01.30.90.5-1.3-1.11.3-0.1-0.31.81.6-0.20.1-0.2-0.21.01.10.6
Delta time in closed arm before/after self-admin0.70.62.70.4-0.5-0.50.70.6-0.3-0.6-0.3-0.0-0.90.10.1-0.00.71.1-0.40.4-0.1-1.41.31.21.21.11.6
Delta time in open arm before/after self-admin3.13.17.1-1.51.51.6-1.8-1.81.41.81.31.22.4-1.3-1.11.2-2.6-2.60.2-0.11.42.7-2.6-2.3-1.1-1.6-2.1
Diff in mean of infusions in LGA sessions0.60.72.80.1-0.2-0.20.40.4-0.1-0.40.00.3-0.8-0.3-0.40.30.81.00.10.8-0.9-1.41.41.41.61.41.7
Delay discount exponential model param1.82.13.6-1.51.61.6-1.7-1.71.51.71.41.41.8-1.5-1.31.6-1.9-1.70.80.70.61.8-1.6-1.60.0-0.3-1.0
Extinction: sum of active levers before priming0.40.52.5-0.70.70.7-0.6-0.60.70.50.80.70.1-0.4-0.40.30.20.11.61.00.3-0.20.10.60.81.30.7
Active lever presses in extinction session 60.30.31.0-0.60.60.6-0.5-0.50.60.40.60.50.1-0.4-0.40.30.1-0.00.90.91.0-0.10.10.20.70.70.5
Bone: final force0.40.72.1-1.00.90.9-0.7-0.71.00.71.11.00.3-0.9-1.00.7-0.1-0.00.91.40.4-0.20.20.21.40.90.9
Bone: final moment0.71.13.2-1.31.21.1-1.0-1.01.31.01.41.30.5-1.2-1.31.0-0.3-0.21.21.80.5-0.10.10.21.71.11.0
Food consumed during 24 hour testing period1.41.94.2-1.61.51.6-1.4-1.41.61.31.61.70.9-1.8-1.71.6-0.9-0.31.12.00.60.2-0.10.12.01.51.2
Glucose1.62.54.11.7-1.8-1.81.81.8-1.7-1.8-1.6-1.6-1.91.21.7-1.31.81.9-1.6-0.8-2.0-1.71.71.60.0-0.01.0
Heart weight2.94.58.1-2.82.52.5-2.4-2.42.72.42.82.72.0-2.7-2.52.6-1.7-1.41.52.91.51.1-1.2-0.82.00.60.6
Delay discount hyperbolic model param1.61.83.1-1.41.51.5-1.6-1.61.31.61.31.21.7-1.4-1.21.5-1.7-1.60.90.60.41.8-1.6-1.5-0.1-0.2-1.0
Intermittent access intake day 1-15 change0.30.62.20.7-0.7-0.70.50.5-0.7-0.5-0.8-0.9-0.10.90.9-0.70.2-0.0-0.4-1.2-0.40.4-0.3-0.8-1.5-1.1-1.3
Intermittent access intake escalation0.30.62.40.8-0.7-0.70.60.6-0.8-0.5-0.9-0.9-0.21.01.0-0.80.2-0.0-0.5-1.3-0.40.4-0.3-0.8-1.5-1.1-1.3
Intermittent access intake escalation 21.11.21.91.3-1.3-1.31.31.3-1.3-1.2-1.4-1.4-1.01.21.3-1.01.01.0-1.1-1.3-1.2-0.50.60.2-1.1-0.7-0.4
Intermitt. access day 1 inactive lever presses0.10.41.3-0.70.60.6-0.5-0.50.80.60.80.90.3-0.8-0.70.9-0.2-0.30.71.00.2-0.30.20.11.10.80.8
Intermitt. access day 15 inactive lever presses0.30.52.3-0.40.30.3-0.1-0.20.50.20.60.7-0.3-0.5-0.50.60.30.40.71.1-0.3-0.90.70.61.51.41.4
Intermitt. access escalation Index0.20.30.50.7-0.7-0.70.70.7-0.7-0.6-0.7-0.7-0.50.40.5-0.50.50.3-0.7-0.70.6-0.30.20.2-0.5-0.5-0.2
Intermittent access day 1 total infusions0.50.81.9-1.01.11.1-1.0-1.01.01.01.00.80.9-1.1-1.21.1-0.9-0.80.90.81.40.7-0.6-0.40.60.5-0.1
Intermittent access day 15 total infusions0.20.41.5-0.00.10.1-0.3-0.20.00.3-0.1-0.20.60.0-0.10.2-0.6-0.7-0.1-0.60.80.9-0.8-1.1-1.0-0.8-1.2
Intermittent access terminal intake (last 3 days)0.20.20.8-0.20.30.3-0.4-0.30.20.40.1-0.00.5-0.2-0.30.4-0.5-0.60.3-0.20.90.7-0.6-0.9-0.5-0.3-0.8
Intermittent access total infusions0.50.61.8-0.60.70.7-0.8-0.80.60.80.50.30.9-0.6-0.70.7-0.8-0.90.60.11.31.0-1.0-1.0-0.4-0.4-1.0
Intermittent access day 1 locomotion0.20.20.8-0.10.10.1-0.2-0.20.10.30.1-0.00.5-0.2-0.30.3-0.4-0.6-0.1-0.40.90.5-0.6-0.7-0.5-0.8-0.8
Intermittent access day 15 total locomotion0.81.53.7-1.01.11.1-1.2-1.21.01.30.90.81.5-0.8-0.90.9-1.4-1.70.80.01.41.7-1.6-1.9-0.7-0.9-1.6
Intermittent access total locomotion1.82.25.5-1.31.41.4-1.5-1.51.31.51.21.11.8-1.1-1.21.1-1.5-2.01.30.32.01.8-1.9-2.3-0.7-0.7-1.7
Intermittent access standard deviation0.10.21.2-0.50.40.4-0.4-0.40.50.50.50.50.4-0.5-0.40.7-0.1-0.40.80.40.60.2-0.4-1.10.00.0-0.4
Left kidney weight12.859.485.4-9.29.29.2-9.1-9.19.29.09.28.78.0-8.5-8.78.2-7.3-7.38.07.66.95.9-6.0-5.24.42.8-0.7
Right kidney weight13.461.190.9-9.49.49.4-9.1-9.19.59.09.59.17.6-9.0-8.98.7-6.7-6.78.68.66.65.0-5.2-4.15.74.00.5
Cocaine induced anxiety0.81.13.4-1.31.21.2-1.1-1.11.31.11.41.20.7-1.1-1.10.9-0.1-0.71.91.60.40.1-0.3-0.31.20.90.4
Post-drug Anxiety0.20.20.90.0-0.1-0.20.30.30.0-0.20.10.1-0.50.20.2-0.30.90.30.60.50.2-0.80.50.30.60.50.5
Baseline Anxiety1.71.93.51.7-1.7-1.71.61.6-1.7-1.6-1.8-1.6-1.31.71.6-1.50.81.1-1.9-1.7-0.4-0.80.70.5-1.2-0.7-0.1
Tail length0.20.71.91.0-0.9-0.90.80.8-1.0-0.8-1.1-1.0-0.41.01.0-1.00.10.3-1.4-1.3-0.40.1-0.10.1-1.1-0.9-0.7
Length with tail0.10.61.1-0.81.01.0-1.0-1.00.80.90.80.80.9-1.0-0.70.9-0.9-0.70.60.70.70.8-0.7-0.30.40.5-0.1
Length without tail0.92.96.5-1.81.81.8-1.6-1.61.81.51.91.90.8-2.2-1.82.1-0.6-0.42.22.50.7-0.10.20.52.52.61.7
Times rat made contact with spout0.50.62.2-0.90.80.8-0.6-0.60.90.71.01.00.3-1.0-1.00.9-0.2-0.10.51.40.2-0.20.10.31.50.70.9
Lifetime Intake0.70.82.1-0.90.90.9-1.0-1.00.81.00.80.51.1-0.9-1.00.9-1.0-1.10.70.41.41.1-1.1-1.0-0.1-0.3-0.9
Liver weight, left0.20.41.1-0.70.70.7-0.7-0.70.70.70.70.70.6-0.3-0.60.3-0.5-0.71.00.40.60.4-0.4-0.60.20.4-0.1
Liver weight, right0.10.10.3-0.40.50.4-0.4-0.40.40.40.40.30.30.0-0.2-0.2-0.3-0.30.30.40.50.3-0.2-0.20.10.10.0
Locomotor activity1.42.14.0-1.71.61.6-1.6-1.61.61.71.61.51.7-2.0-1.61.9-1.8-1.40.41.11.41.5-1.4-1.20.5-0.2-0.4
Locomotor testing distance0.10.21.10.4-0.5-0.50.40.4-0.4-0.4-0.5-0.4-0.20.10.3-0.10.00.2-1.0-0.5-0.0-0.00.1-0.1-0.4-0.7-0.2
Locomotor testing rearing0.20.41.7-0.50.50.5-0.6-0.60.50.60.50.40.8-0.7-0.40.6-0.8-0.6-0.20.21.30.8-0.8-0.8-0.3-0.6-0.6
Locomotion in novel chamber1.41.88.10.3-0.3-0.3-0.00.0-0.40.1-0.6-0.70.90.50.3-0.4-1.2-1.4-1.2-1.91.41.7-1.8-1.9-2.5-2.8-2.6
Locomotion in novel chamber post-restriction0.60.92.01.1-1.0-1.00.90.9-1.2-1.0-1.2-1.0-0.71.21.4-1.30.80.6-0.7-1.2-1.2-0.10.30.3-1.3-0.7-0.6
Fecal boli incidents, locomotor time 10.20.21.2-0.40.60.6-0.5-0.50.40.40.40.40.3-0.3-0.40.3-0.2-0.21.10.40.30.10.10.10.51.10.4
Change in fecal boli incidents, locomotor task0.30.31.1-0.30.40.4-0.5-0.50.30.50.20.20.8-0.2-0.20.2-0.8-0.8-0.4-0.2-0.11.1-0.9-0.7-0.6-0.9-0.9
Time >=10cm from walls, locomotor time 10.30.30.7-0.60.60.6-0.6-0.60.60.60.70.50.5-0.6-0.60.8-0.3-0.20.80.50.80.3-0.4-0.20.20.0-0.2
Bouts of movement, locomotor time 10.20.20.60.2-0.2-0.20.30.3-0.2-0.3-0.1-0.1-0.50.10.2-0.10.80.40.40.2-0.4-0.70.60.80.40.60.6
Total resting periods, locomotor time 10.30.41.30.4-0.4-0.50.60.6-0.3-0.5-0.2-0.3-0.80.20.3-0.21.10.70.40.2-0.4-1.10.91.00.50.70.8
Rest time, locomotor task time 10.40.52.3-0.80.90.8-0.8-0.80.80.70.80.60.4-0.8-0.60.6-0.2-0.51.50.80.20.2-0.2-0.20.51.00.2
Distance moved, locomotor task time 10.00.10.60.1-0.2-0.20.20.2-0.1-0.1-0.10.00.0-0.1-0.20.2-0.20.1-0.8-0.10.2-0.10.2-0.30.3-0.40.1
Vertical activity count, locomotor time 10.10.21.30.4-0.6-0.60.60.6-0.4-0.5-0.4-0.3-0.40.20.1-0.10.30.7-1.1-0.20.0-0.50.50.40.3-0.40.3
Time >=10cm from walls, locomotor time 20.10.21.00.3-0.3-0.30.20.2-0.3-0.2-0.4-0.40.00.30.4-0.30.20.00.2-0.70.30.3-0.4-0.3-1.0-0.7-1.0
Bouts of movement, locomotor time 20.71.13.10.9-0.9-1.01.11.1-0.8-1.1-0.8-0.8-1.31.01.3-1.21.81.20.2-0.1-1.5-1.41.21.30.00.50.7
Total resting periods, locomotor time 20.81.43.90.9-1.0-1.01.11.1-0.9-1.2-0.8-0.9-1.51.01.3-1.22.01.40.4-0.0-1.8-1.61.41.50.20.81.0
Rest time, locomotor task time 20.20.20.60.4-0.4-0.50.50.5-0.4-0.5-0.4-0.4-0.50.40.5-0.50.50.5-0.2-0.3-0.8-0.50.40.6-0.20.10.3
Distance moved, locomotor task time 21.01.22.1-1.11.21.2-1.3-1.31.11.31.01.01.4-1.0-1.11.0-1.5-1.30.60.51.21.5-1.2-1.2-0.0-0.3-0.8
Vertical activity count, locomotor time 20.91.22.2-1.11.21.2-1.3-1.31.11.31.01.01.4-0.9-1.11.1-1.4-1.30.90.41.11.4-1.3-1.5-0.1-0.2-0.9
Light reinforcement 11.22.96.7-1.51.51.5-1.7-1.71.51.91.31.62.2-1.3-1.61.3-2.6-2.40.20.12.12.3-2.2-2.1-0.5-1.2-1.6
Light reinforcement 21.92.95.3-1.61.71.6-1.8-1.81.51.91.41.42.1-1.2-1.51.3-2.0-2.31.50.32.12.2-2.3-2.1-0.8-0.9-1.8
Bone: marrow area3.57.511.2-3.03.13.1-3.2-3.23.03.22.92.73.3-2.7-2.52.6-3.1-3.22.01.72.93.2-3.1-2.80.0-0.6-1.8
Bone: maximum diameter3.97.410.8-3.13.23.2-3.3-3.33.03.23.02.73.3-2.6-2.42.4-3.1-2.92.12.02.73.1-2.9-2.50.4-0.2-1.4
Bone: maximum force0.91.63.4-1.61.51.5-1.3-1.41.61.31.61.51.0-1.6-1.41.4-0.7-0.51.31.90.90.4-0.4-0.31.50.90.7
Bone: maximum moment1.32.24.9-1.91.81.8-1.6-1.61.91.61.91.81.2-1.9-1.71.7-0.9-0.71.52.21.00.5-0.5-0.31.81.10.8
Mean time between licks in bursts1.12.84.61.9-1.9-1.91.81.8-2.0-1.8-2.0-2.1-1.42.02.1-2.11.21.3-2.1-1.8-1.4-0.60.70.8-1.6-1.3-0.5
Mean num. licks in bursts1.42.25.3-1.71.61.5-1.3-1.41.81.41.91.90.7-1.7-1.91.8-0.4-0.61.92.30.4-0.20.10.22.31.71.3
Cd content in liver0.30.30.8-0.60.40.4-0.4-0.50.60.60.50.60.7-0.8-0.60.9-0.8-0.6-0.60.40.50.5-0.5-0.40.3-0.6-0.2
Co content in liver0.30.30.8-0.50.30.3-0.3-0.40.50.50.50.70.7-0.7-0.70.6-0.9-0.7-0.70.1-0.20.5-0.6-0.70.1-0.8-0.3
Cu content in liver3.13.78.02.4-2.3-2.32.12.1-2.4-2.0-2.5-2.3-1.52.32.2-2.11.31.0-1.6-2.8-1.4-0.60.60.0-2.5-1.5-1.2
Fe content in liver0.60.71.4-1.00.80.8-0.8-0.80.90.90.90.90.9-1.1-1.11.0-1.0-0.6-0.40.81.20.6-0.6-0.40.8-0.30.1
K content in liver0.30.31.4-0.30.40.4-0.4-0.40.40.50.40.70.3-0.3-0.70.3-0.4-0.51.20.10.6-0.0-0.1-0.50.40.90.1
Mg content in liver0.10.10.60.2-0.1-0.20.20.2-0.1-0.1-0.10.1-0.30.2-0.2-0.20.20.10.7-0.20.2-0.50.4-0.00.20.80.3
Mn content in liver0.70.81.5-0.91.01.0-1.0-1.00.91.10.90.91.1-0.7-1.10.5-1.2-1.20.90.30.60.9-1.1-1.2-0.00.1-0.6
Na content in liver1.61.73.11.5-1.4-1.41.41.4-1.6-1.5-1.6-1.7-1.41.51.5-1.81.21.5-1.0-1.2-1.1-0.91.11.1-0.70.10.3
Rb content in liver0.10.10.40.0-0.2-0.20.30.2-0.0-0.20.00.0-0.4-0.1-0.0-0.10.50.4-0.10.4-0.2-0.60.50.60.60.20.6
Se content in liver0.10.10.50.4-0.4-0.40.30.3-0.4-0.2-0.4-0.2-0.10.30.10.0-0.1-0.1-0.3-0.70.10.0-0.0-0.3-0.5-0.3-0.4
Sr content in liver0.70.61.01.0-0.9-0.90.90.9-0.9-0.9-0.9-0.8-0.90.90.8-0.70.90.7-0.3-0.8-1.0-0.80.70.5-0.40.10.2
Zn content in liver0.50.61.3-0.70.70.7-0.8-0.80.80.80.71.00.8-0.8-0.91.1-0.9-0.90.70.30.80.5-0.6-0.90.20.2-0.2
Bone: minimum diameter1.32.46.2-1.11.31.3-1.5-1.51.11.50.90.92.0-0.8-0.60.6-2.2-2.10.2-0.31.62.5-2.3-2.3-1.4-1.5-2.1
Time in familiar zone, hab. session 10.70.61.2-0.90.90.9-0.9-1.00.90.90.91.00.9-0.7-0.80.5-1.1-1.00.50.51.00.8-0.8-0.70.30.1-0.2
Time in novel zone, hab. session 10.20.21.20.3-0.4-0.40.40.4-0.3-0.3-0.4-0.5-0.20.10.4-0.00.20.4-1.1-0.3-0.20.1-0.10.0-0.5-1.0-0.4
Total zone transitions, hab. session 11.41.92.71.6-1.6-1.61.61.6-1.6-1.6-1.6-1.4-1.61.61.5-1.51.41.4-1.2-1.2-1.2-1.31.31.1-0.4-0.10.5
Total locomotion distance, hab. session 10.20.31.1-0.10.30.2-0.4-0.40.20.40.10.30.60.2-0.1-0.2-0.6-0.80.5-0.50.70.7-0.7-1.1-0.8-0.4-0.9
Locomotion velocity, hab. session 10.20.31.2-0.20.40.4-0.5-0.50.30.50.20.40.60.1-0.3-0.1-0.6-0.90.8-0.40.80.7-0.7-1.1-0.6-0.1-0.8
Time in familiar zone, hab. session 20.20.20.7-0.10.10.1-0.2-0.20.10.20.00.10.40.20.1-0.2-0.5-0.60.1-0.50.90.6-0.6-0.8-0.7-0.5-0.8
Time in novel zone, hab. session 20.10.10.80.0-0.2-0.20.30.3-0.1-0.2-0.0-0.1-0.2-0.3-0.10.30.20.4-0.90.3-0.6-0.40.40.70.6-0.20.5
Total zone transitions, hab. session 20.50.61.9-0.70.70.7-0.6-0.60.70.60.81.00.3-0.9-0.91.1-0.4-0.20.90.90.5-0.30.30.31.31.41.0
Total locomotion distance, hab. session 20.30.41.0-0.60.70.7-0.7-0.70.60.70.60.70.7-0.4-0.60.5-0.7-0.80.90.31.00.5-0.5-0.70.10.5-0.2
Locomotion velocity, hab. session 20.20.20.9-0.40.50.5-0.5-0.50.40.50.40.60.4-0.3-0.50.3-0.5-0.61.00.20.70.2-0.3-0.50.20.70.0
Novel to familiar place preference ratio0.30.40.8-0.70.60.6-0.6-0.60.70.70.70.60.7-0.9-0.50.8-0.6-0.5-0.10.60.50.7-0.6-0.40.2-0.5-0.3
Novelty place preference0.70.71.2-1.00.90.9-0.9-0.91.01.00.90.81.1-1.1-0.71.0-1.0-0.9-0.00.70.81.0-1.0-0.60.2-0.6-0.5
Time in novel zone, NPP test0.91.01.6-1.11.01.0-1.0-1.01.11.11.00.91.2-1.3-0.81.2-1.2-0.9-0.20.81.01.2-1.1-0.70.2-0.8-0.5
Total zone transitions, NPP test0.10.20.70.3-0.3-0.30.40.4-0.3-0.4-0.3-0.1-0.50.10.20.00.40.6-0.10.0-0.5-0.70.70.70.60.80.8
Total locomotion distance, NPP test0.40.61.4-0.60.70.7-0.8-0.80.60.80.60.70.9-0.5-0.70.5-1.1-1.00.6-0.11.00.9-1.0-1.2-0.3-0.1-0.7
Locomotion velocity, NPP test0.20.20.9-0.10.30.3-0.4-0.40.20.40.10.20.50.1-0.2-0.0-0.6-0.70.7-0.50.60.6-0.6-0.9-0.6-0.0-0.7
Intraocular pressure0.10.11.0-0.10.10.1-0.1-0.10.00.00.0-0.20.1-0.00.10.0-0.00.1-0.30.01.00.3-0.3-0.3-0.3-0.5-0.3
Delta distance traveled before/after self-admin1.61.73.7-1.41.31.4-1.4-1.41.41.51.31.51.6-1.3-1.41.2-1.9-1.70.10.71.31.5-1.4-1.20.3-0.5-0.6
Delta ambulatory time before/after self-admin1.11.43.0-1.31.21.2-1.3-1.31.21.31.21.31.4-1.3-1.31.2-1.7-1.3-0.10.71.41.2-1.1-1.10.4-0.4-0.3
Parametrial fat weight0.51.32.51.3-1.4-1.41.31.3-1.3-1.2-1.4-1.5-0.81.41.1-1.30.60.6-1.5-1.6-0.7-0.50.30.1-1.2-1.2-0.5
Pavlov. Cond. lever latency0.70.91.8-1.31.11.1-1.0-1.01.31.11.31.10.8-1.1-1.01.2-0.4-0.81.01.31.00.5-0.6-0.50.70.10.0
Pavlov. Cond. magazine entry latency2.93.75.52.2-2.2-2.22.22.2-2.2-2.3-2.1-2.0-2.21.72.0-1.82.02.2-1.7-1.4-2.4-1.92.01.8-0.30.21.0
Pavlov. Cond. change in total contacts3.23.44.52.1-2.1-2.12.12.1-2.1-2.1-2.1-1.9-2.11.91.9-2.01.81.9-1.7-1.4-2.1-1.81.91.7-0.20.10.9
Pavlov. Cond. index score2.43.04.92.0-1.9-1.92.02.0-2.0-2.0-1.9-1.8-2.01.61.8-1.71.72.0-1.5-1.3-2.2-1.71.91.7-0.20.41.0
Pavlov. Cond. latency score1.62.03.21.7-1.6-1.51.61.6-1.7-1.6-1.7-1.5-1.51.41.5-1.51.11.5-1.4-1.2-1.8-1.21.41.3-0.30.20.7
Pavlov. Cond. lever contacts1.92.33.81.9-1.8-1.71.71.7-1.9-1.7-2.0-1.7-1.51.81.7-1.91.11.4-1.4-1.8-1.6-1.01.10.9-1.0-0.10.1
Pavlov. Cond. magazine entry number4.15.17.9-2.52.52.5-2.6-2.62.52.62.52.42.7-2.1-2.42.2-2.5-2.61.81.52.82.3-2.4-2.30.3-0.3-1.2
Pavlov. Cond. intertrial magazine entries0.10.10.20.3-0.4-0.40.40.4-0.3-0.3-0.3-0.1-0.30.40.2-0.30.10.3-0.4-0.4-0.2-0.30.20.10.0-0.20.1
Pavlov. Cond. lever-magazine prob. diff.2.83.45.02.1-2.1-2.02.12.1-2.1-2.2-2.1-2.0-2.11.82.0-1.91.82.0-1.6-1.5-2.2-1.71.91.7-0.40.30.9
Pavlov. Cond. response bias3.84.76.52.6-2.5-2.52.52.5-2.5-2.5-2.5-2.4-2.42.22.4-2.32.22.3-1.7-1.8-2.5-2.02.11.8-0.70.10.8
Pavlov. Cond. lever latency0.30.41.70.5-0.6-0.60.50.6-0.5-0.5-0.5-0.8-0.30.40.7-0.20.30.3-1.3-0.5-0.10.1-0.20.0-0.8-1.3-0.5
Pavlov. Cond. magazine entry latency0.70.82.10.8-0.7-0.70.80.8-0.7-0.9-0.6-0.4-1.20.80.5-0.91.20.90.6-0.2-0.7-1.51.41.10.71.41.1
Pavlov. Cond. change in total contacts0.50.73.9-0.40.50.5-0.3-0.30.50.30.60.9-0.2-0.5-0.90.40.10.21.21.0-0.4-0.90.90.71.72.01.5
Pavlov. Cond. index score0.30.42.20.3-0.2-0.20.20.2-0.2-0.3-0.10.1-0.60.3-0.1-0.40.60.41.00.1-0.6-1.00.90.70.81.51.0
Pavlov. Cond. latency score0.30.42.20.3-0.2-0.20.20.2-0.2-0.3-0.20.1-0.60.3-0.1-0.50.60.41.00.1-0.5-0.90.90.60.81.50.9
Pavlov. Cond. lever contacts0.20.32.0-0.30.40.4-0.3-0.30.30.30.40.6-0.0-0.2-0.50.1-0.0-0.11.20.5-0.1-0.40.40.20.91.40.7
Pavlov. Cond. magazine entry number0.30.42.0-0.30.20.2-0.3-0.30.20.30.2-0.10.6-0.40.00.5-0.5-0.4-0.9-0.00.61.0-1.0-0.7-0.8-1.4-0.9
Pavlov. Cond. intertrial magazine entries0.30.51.9-0.80.70.7-0.6-0.60.80.50.90.60.2-1.1-0.61.10.20.20.61.40.3-0.10.10.31.00.50.7
Pavlov. Cond. lever-magazine prob. diff.0.20.31.90.2-0.1-0.10.20.1-0.1-0.2-0.10.2-0.50.3-0.1-0.40.40.21.00.0-0.4-0.80.70.50.61.40.7
Pavlov. Cond. response bias0.30.52.70.2-0.1-0.10.20.2-0.1-0.3-0.10.2-0.60.1-0.1-0.30.60.60.90.3-0.7-1.01.10.91.01.61.2
Time in closed arm before self-admin2.43.04.72.1-2.0-2.01.91.9-2.1-1.9-2.1-2.1-1.52.22.2-2.21.50.9-1.5-2.1-1.5-0.80.80.5-1.8-1.2-0.8
Time in closed arm after self-admin1.51.73.51.6-1.6-1.61.61.6-1.6-1.5-1.6-1.4-1.21.41.3-1.40.90.9-1.9-1.5-0.5-0.90.90.7-0.8-0.8-0.0
Time in open arm before self-admin0.10.10.40.2-0.1-0.10.10.1-0.2-0.2-0.2-0.2-0.30.40.3-0.30.40.50.40.00.4-0.20.40.30.10.60.4
Time in open arm after self-admin2.83.14.7-1.82.02.0-2.1-2.11.82.01.71.52.2-1.5-1.41.4-2.0-2.11.80.71.82.2-2.2-2.1-0.4-0.2-1.5
Bone: periosteal estimation2.34.97.6-2.42.52.5-2.6-2.62.42.62.32.22.7-2.0-1.91.8-2.6-2.61.61.32.32.7-2.6-2.3-0.0-0.6-1.5
Bone: periosteal perimeter2.44.29.6-1.92.12.1-2.3-2.31.82.21.71.42.7-1.5-1.21.2-2.6-2.50.80.52.33.1-2.9-2.6-1.1-1.5-2.2
Bone: post-yield work0.71.13.90.0-0.2-0.20.50.50.0-0.50.20.1-1.0-0.50.00.41.21.4-0.01.3-1.2-1.61.61.61.91.32.0
Progressive ratio test 1 active lever presses0.10.11.0-0.00.00.0-0.0-0.00.00.00.0-0.30.0-0.1-0.20.10.2-0.10.30.01.00.1-0.1-0.4-0.2-0.2-0.3
Progressive ratio test 1 breakpoint0.10.10.60.2-0.2-0.20.20.2-0.2-0.2-0.2-0.5-0.20.1-0.0-0.10.40.10.1-0.10.8-0.10.1-0.3-0.3-0.2-0.3
Progressive ratio test 1 inactive lever presses0.30.41.3-0.70.60.6-0.6-0.60.70.70.70.50.6-0.7-0.50.7-0.6-0.70.40.51.20.4-0.6-0.60.2-0.1-0.2
Progressive ratio test 2 active lever presses0.91.12.5-1.11.11.1-1.0-1.01.21.01.21.10.6-1.3-1.41.4-0.3-0.51.61.41.10.1-0.1-0.31.21.10.5
Progressive ratio test 2 breakpoint0.80.92.2-1.11.01.0-1.0-1.01.11.01.11.00.6-1.2-1.31.3-0.3-0.51.51.21.20.2-0.2-0.41.00.90.4
Progressive ratio test 2 inactive lever presses0.10.20.8-0.30.40.4-0.3-0.30.30.30.30.20.1-0.4-0.50.6-0.0-0.10.90.40.5-0.10.2-0.10.60.90.4
Incentive Sensitization - Responses1.42.03.6-1.61.51.5-1.3-1.41.71.41.71.80.9-1.8-1.81.9-0.6-0.61.81.91.30.1-0.2-0.21.81.40.9
Incentive Sensitization - Breakpoint1.72.24.1-1.71.61.6-1.5-1.51.81.51.81.80.9-1.9-1.92.0-0.7-0.72.02.01.30.1-0.2-0.21.91.50.9
Sum of active levers in priming session hrs 5-60.40.40.7-0.70.70.7-0.7-0.70.70.70.70.50.8-0.6-0.60.6-0.7-0.80.60.30.70.7-0.8-0.8-0.1-0.2-0.5
Progressive ratio0.81.22.91.0-1.0-1.01.11.1-1.0-1.2-0.9-1.0-1.40.90.8-0.81.51.7-0.4-0.1-0.8-1.41.61.70.60.81.2
Food seeking constrained by brief footshock0.40.51.2-0.70.60.6-0.6-0.60.80.70.70.90.6-1.0-1.01.1-0.9-0.6-0.30.6-0.10.3-0.2-0.60.7-0.00.4
Seeking ratio, punishment vs. effort0.60.81.4-1.00.90.9-1.0-1.01.01.01.01.21.0-1.1-1.11.1-1.2-1.10.50.60.10.7-0.8-1.10.4-0.0-0.2
Retroperitoneal fat weight1.25.210.9-2.82.92.9-2.7-2.72.82.62.82.52.0-2.7-2.52.4-1.5-1.63.32.80.81.2-1.2-1.01.92.00.6
Reaction time number correct0.51.02.01.2-1.0-1.00.90.9-1.2-1.0-1.3-1.4-0.81.31.4-1.40.80.7-0.5-1.3-0.4-0.20.40.5-1.2-0.4-0.5
Reaction time mean minus median0.00.10.30.1-0.1-0.00.10.1-0.2-0.2-0.2-0.2-0.20.20.1-0.30.10.5-0.40.1-0.0-0.10.30.50.30.20.4
Reaction time mean minus median AUC0.10.30.6-0.60.80.8-0.7-0.70.60.60.60.30.5-0.5-0.40.3-0.4-0.20.70.70.50.6-0.3-0.00.30.50.1
Reaction time num false alarms0.50.63.30.7-0.8-0.70.70.7-0.8-0.6-0.8-0.8-0.20.80.9-1.2-0.00.3-1.8-0.9-0.50.3-0.00.0-0.9-1.4-0.6
Reaction time num false alarms AUC0.20.32.70.5-0.5-0.50.40.4-0.5-0.4-0.6-0.5-0.10.50.6-0.9-0.20.2-1.7-0.6-0.40.20.00.1-0.5-1.0-0.3
Reaction time trials correct on left0.51.02.01.2-1.0-1.00.90.9-1.2-1.0-1.3-1.4-0.81.31.4-1.40.80.7-0.5-1.3-0.4-0.20.40.5-1.2-0.4-0.5
Reaction time trials on left0.61.12.21.3-1.1-1.11.01.0-1.3-1.1-1.3-1.5-0.91.41.4-1.40.90.7-0.5-1.3-0.4-0.30.50.5-1.2-0.3-0.4
Reaction time mean0.50.81.90.9-0.9-0.91.01.0-0.9-1.0-0.8-0.9-1.10.70.7-0.91.21.4-0.6-0.3-0.4-1.01.11.00.00.10.7
Reaction time mean AUC0.50.81.90.9-0.9-0.90.90.9-0.9-1.0-0.8-0.9-1.10.70.7-0.91.21.4-0.4-0.2-0.5-1.01.11.10.10.30.7
Median of all reaction times0.81.12.41.1-1.1-1.21.21.2-1.0-1.2-1.0-1.0-1.40.80.8-0.91.51.5-0.7-0.4-0.5-1.31.31.20.10.10.8
Reaction time omissions0.50.71.40.8-0.8-0.80.90.9-0.8-1.0-0.8-0.9-1.00.80.9-1.01.01.2-0.8-0.3-0.4-0.91.01.00.10.20.7
Reaction time false alarm rate0.10.11.6-0.1-0.1-0.10.10.00.00.10.00.10.2-0.10.0-0.3-0.5-0.1-1.3-0.1-0.30.3-0.2-0.2-0.0-0.9-0.1
Reaction time premature initiation rate1.01.47.2-0.80.90.9-0.6-0.70.90.51.00.9-0.2-0.9-1.10.90.50.52.31.7-0.1-1.00.90.72.02.71.7
Reaction time premature initiations0.40.75.0-0.20.30.3-0.1-0.10.2-0.00.30.2-0.6-0.1-0.40.10.80.81.81.0-0.0-1.01.00.91.32.21.3
Std. dev. reaction times0.10.10.50.3-0.3-0.30.30.3-0.3-0.4-0.3-0.4-0.40.20.2-0.30.40.7-0.30.00.2-0.30.50.40.10.10.4
Reaction time trials completed0.61.12.21.3-1.1-1.11.01.0-1.3-1.1-1.3-1.5-0.91.41.4-1.40.90.7-0.5-1.3-0.4-0.30.50.5-1.2-0.3-0.4
Reaction time trials AUC0.40.71.51.0-0.8-0.80.70.8-1.1-0.9-1.1-1.2-0.71.21.2-1.20.70.5-0.3-1.1-0.1-0.10.30.4-1.1-0.3-0.5
Run reversals in cocaine runway, females1.61.64.61.3-1.4-1.41.21.2-1.3-1.0-1.4-1.3-0.41.41.2-1.20.3-0.1-1.5-2.20.40.2-0.4-0.8-2.0-2.1-1.7
Run reversals in cocaine runway, males0.70.71.6-0.91.01.0-1.0-1.00.91.00.80.81.1-0.8-0.40.6-1.3-0.90.10.5-0.11.3-1.0-0.9-0.0-0.3-0.5
Latency to leave start box in cocaine runway1.11.22.2-1.21.21.2-1.2-1.21.31.21.21.51.2-1.2-1.31.4-1.2-0.91.01.00.90.8-0.9-0.90.70.4-0.1
Latency to leave start box in cocaine runway, F0.50.61.6-0.90.80.8-0.8-0.80.90.80.91.30.6-0.9-1.11.0-0.7-0.30.70.9-0.00.2-0.3-0.10.90.70.5
Latency to leave start box in cocaine runway, M1.11.03.0-1.01.01.0-1.1-1.11.01.10.90.91.2-0.8-0.90.9-1.0-1.20.80.51.71.1-1.2-1.5-0.2-0.3-0.9
Std. dev. time between licks in bursts0.40.61.20.8-0.6-0.60.70.7-0.8-0.8-0.8-0.8-0.91.00.8-1.10.90.80.3-0.5-0.9-0.70.80.8-0.20.70.4
Total sessions with >9 infusions2.22.63.8-1.91.91.9-1.9-1.91.81.91.81.71.8-2.0-1.91.9-1.6-1.61.41.51.81.4-1.3-1.10.90.5-0.3
Short access day 1 total inactive lever presses2.33.06.3-2.11.92.0-1.8-1.82.11.92.12.11.5-2.5-2.12.5-1.6-1.21.02.20.80.6-0.6-0.22.11.21.0
Short access day 10 total inactive lever presses1.02.44.4-1.81.71.7-1.7-1.71.81.81.81.91.6-1.8-1.81.8-1.8-1.40.81.42.11.1-1.2-1.21.10.20.0
Short access day 1 total infusions0.81.02.3-1.21.11.1-1.1-1.11.21.11.21.21.1-1.5-1.31.5-1.3-0.90.11.00.60.7-0.6-0.21.00.20.2
Short access day 10 total infusions0.10.10.4-0.10.20.2-0.3-0.20.10.20.1-0.20.2-0.1-0.20.20.1-0.30.60.10.50.4-0.3-0.3-0.30.0-0.5
Short access total infusions1.01.22.0-1.31.31.3-1.3-1.31.31.31.31.01.2-1.4-1.41.4-1.0-1.01.11.11.20.9-0.8-0.50.60.4-0.2
Short access day 1 locomotion0.50.61.5-0.80.70.6-0.7-0.70.80.90.80.90.9-0.9-0.91.0-1.0-1.00.10.41.20.7-0.8-0.80.2-0.6-0.5
Short access day 10 total locomotion0.20.41.00.7-0.7-0.70.60.6-0.7-0.5-0.7-0.6-0.30.70.7-0.60.3-0.1-0.6-1.0-0.3-0.0-0.1-0.4-1.0-0.9-0.7
Short access total locomotion0.20.20.7-0.00.00.0-0.1-0.10.00.2-0.0-0.00.4-0.1-0.10.0-0.4-0.6-0.2-0.40.80.5-0.6-0.8-0.6-0.8-0.8
One hour access (0.3 mA shock)0.30.31.2-0.30.40.4-0.5-0.50.30.50.2-0.10.6-0.3-0.40.4-0.3-0.60.9-0.21.10.8-0.7-0.7-0.6-0.2-1.0
Compulsive drug intake1.01.25.1-0.30.30.4-0.1-0.20.30.00.40.7-0.5-0.4-0.60.40.31.00.51.3-1.4-1.11.32.02.12.22.2
One hour access (shock baseline)0.81.25.6-0.00.10.0-0.3-0.2-0.00.3-0.1-0.60.80.10.1-0.1-0.5-1.20.1-1.11.71.4-1.5-1.8-2.0-1.9-2.4
Social response proportion0.30.30.6-0.60.60.6-0.6-0.60.60.70.60.70.6-0.4-0.50.5-0.6-0.80.60.40.40.5-0.5-0.10.30.2-0.2
Social responses0.10.21.0-0.20.50.5-0.5-0.50.30.40.20.30.50.1-0.30.1-0.5-0.61.0-0.10.10.5-0.4-0.3-0.00.7-0.3
Social time2.73.65.22.1-2.1-2.12.22.2-2.0-2.1-2.0-1.6-2.22.01.9-2.02.12.0-1.4-1.2-2.2-2.22.12.30.00.41.2
Soleus weight0.30.92.7-0.90.80.8-0.6-0.60.90.61.01.00.0-1.1-1.01.20.20.31.21.6-0.4-0.60.50.51.61.51.4
Bone: stiffness0.20.30.80.1-0.2-0.20.40.4-0.1-0.4-0.0-0.2-0.6-0.20.30.00.70.9-0.50.6-0.6-0.70.80.80.80.20.9
Tibialis anterior weight0.00.00.10.2-0.2-0.20.20.2-0.2-0.2-0.2-0.2-0.20.30.2-0.00.20.00.3-0.4-0.3-0.20.0-0.1-0.30.1-0.1
Time to tail flick, vehicle, before self-admin0.30.30.8-0.50.40.4-0.3-0.40.50.40.60.70.1-0.5-0.50.50.2-0.10.90.8-0.9-0.20.20.50.80.70.5
Time to tail flick, vehicle, after self-admin0.10.10.40.1-0.1-0.1-0.00.0-0.10.0-0.1-0.10.10.30.3-0.40.0-0.30.1-0.3-0.30.3-0.3-0.6-0.6-0.5-0.6
Time to tail flick, test, before self-admin0.00.00.2-0.0-0.0-0.0-0.0-0.0-0.00.0-0.0-0.00.2-0.00.10.1-0.2-0.3-0.2-0.20.10.3-0.3-0.3-0.4-0.4-0.4
Time to tail flick, test, after self-admin0.40.40.70.8-0.8-0.80.80.8-0.8-0.7-0.8-0.6-0.60.70.7-0.80.50.4-0.7-0.7-0.0-0.50.40.1-0.5-0.3-0.1
Delta time to tail flick, vehicle, before/after SA0.50.50.9-0.80.80.8-0.7-0.70.80.70.90.80.5-0.9-0.90.9-0.5-0.30.60.90.80.2-0.2-0.70.80.50.4
Delta time to tail flick, test, before/after SA0.30.30.40.6-0.7-0.70.70.6-0.6-0.6-0.6-0.4-0.60.60.4-0.60.40.5-0.6-0.5-0.3-0.60.50.3-0.10.00.2
Tibia length0.20.62.0-0.90.90.9-0.8-0.80.90.80.90.90.7-1.1-0.71.4-0.8-0.40.11.00.40.6-0.4-0.10.70.20.3
Ambulatory time before self-admin0.10.20.60.4-0.4-0.40.40.4-0.4-0.4-0.4-0.3-0.40.30.3-0.2-0.00.5-0.8-0.3-0.4-0.40.50.50.30.30.7
Ambulatory time after self-admin0.10.11.50.2-0.2-0.20.10.1-0.2-0.1-0.20.00.1-0.0-0.10.1-0.7-0.2-1.2-0.40.10.10.0-0.10.1-0.30.2
Bone: tissue strength0.20.20.7-0.50.50.5-0.4-0.40.50.40.60.50.2-0.8-0.60.7-0.10.10.40.80.1-0.10.10.10.80.60.6
Total heroin consumption1.11.32.9-1.21.31.3-1.2-1.21.21.01.31.30.6-1.2-1.21.2-0.4-0.21.71.60.10.1-0.00.31.41.61.0
Bone: trabecular number0.61.03.91.1-1.3-1.31.21.2-1.1-1.0-1.2-1.0-0.70.91.0-0.60.50.6-2.0-1.2-0.2-0.30.30.1-0.9-1.5-0.5
Bone: trabecular spacing1.72.25.4-1.71.91.9-1.8-1.81.71.61.71.51.3-1.6-1.61.4-1.1-1.02.31.60.80.9-0.8-0.61.01.50.3
Bone: trabecular thickness0.10.20.50.5-0.6-0.60.50.5-0.5-0.4-0.5-0.1-0.30.60.3-0.30.10.0-0.5-0.70.0-0.30.2-0.1-0.3-0.3-0.1
Bone: trabecular tissue density0.40.61.10.8-0.8-0.80.90.9-0.7-0.8-0.7-0.6-1.00.70.6-0.71.00.8-0.1-0.4-0.7-1.11.00.80.20.40.6
Water consumed over 24 hours1.31.73.7-1.61.51.5-1.4-1.41.61.41.61.61.2-1.9-1.61.7-1.2-0.70.61.70.70.7-0.7-0.31.40.60.5
Number of responses in last shaping day0.60.61.20.8-1.0-1.01.01.0-0.8-0.9-0.7-0.4-1.00.70.5-0.70.90.8-0.8-0.4-0.8-1.11.00.60.20.00.6