Hub : Genes

Sgtb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Sgtb 0.09 0.07 7.8e-11 0.08 0.08 0.07 0.08 2.5e-09 5.1e-09 3.0e-08 5.6e-09
2 Brain mRNA stability Sgtb 0.08 0.08 4.7e-07 0.08 0.07 0.07 0.07 1.3e-07 2.9e-07 1.9e-07 1.9e-07
3 Brain isoform ratio NM_181629.3 0.03 0.03 1.1e-03 0.03 0.03 0.03 0.03 4.5e-04 4.4e-04 3.6e-04 4.3e-04
4 NAcc gene expression Sgtb 0.02 0.02 7.2e-03 0.01 0.01 0.01 0.01 4.1e-02 2.9e-02 3.0e-02 5.0e-02
5 Brain isoform ratio XM_006231882.4 0.03 0.03 2.7e-03 0.02 0.02 0.02 0.02 3.0e-03 3.6e-03 1.2e-02 3.5e-03
6 Adipose gene expression Sgtb 0.18 0.1 0.0e+00 0.2 0.2 0.2 0.2 2.3e-21 9.8e-22 1.5e-21 2.3e-21
7 LHb mRNA stability Sgtb 0.32 0.2 4.9e-03 0.05 -0.01 0.03 0.02 2.9e-02 7.0e-01 6.9e-02 1.2e-01
8 NAcc mRNA stability Sgtb 0.18 0.15 3.1e-05 0.03 0.04 0.04 0.04 7.0e-05 1.3e-05 4.5e-05 6.4e-05
9 PL mRNA stability Sgtb 0.02 0.02 7.7e-03 0.01 0 0 0.01 1.3e-02 2.7e-01 1.4e-01 4.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.61.11.31.01.1-1.11.11.0-1.10.9-0.91.2
Area under the delay curve0.80.82.4-0.5-1.00.8-0.7-1.00.7-1.01.6-0.2
BMI with tail1.75.66.62.32.3-2.62.42.6-2.42.5-1.72.5
BMI without tail0.30.50.90.90.7-0.80.70.7-0.80.7-0.30.8
Body weight1.77.18.3-2.6-2.82.5-2.8-2.52.7-2.92.8-2.5
Weight adjusted by age0.20.20.4-0.6-0.40.5-0.4-0.50.4-0.50.1-0.5
Bone surface0.00.10.20.10.2-0.20.20.2-0.20.00.10.5
Bone volume0.10.20.40.30.4-0.50.50.5-0.50.3-0.20.7
Breakpoint value in progressive ratio session2.62.94.61.81.6-1.61.81.6-1.81.7-1.22.1
Number of licking bursts3.43.94.32.02.0-2.02.02.1-2.02.0-1.82.0
Context. condit. distance diff. score1.82.13.5-1.4-1.51.4-1.4-1.51.4-1.41.9-1.0
Locomotion velocity, session 10.30.30.6-0.8-0.60.5-0.6-0.50.6-0.40.6-0.6
Locomotion distance, session 10.70.91.2-0.9-0.90.9-1.0-0.90.9-1.01.1-0.8
Locomotion velocity, session 24.04.65.3-2.3-2.12.2-2.2-2.22.2-2.01.9-2.3
Locomotion distance, session 20.60.91.5-1.0-0.90.9-0.9-0.90.9-0.91.2-0.6
Locomotion velocity, session 34.55.36.0-2.5-2.32.3-2.3-2.22.3-2.32.3-2.1
Locomotion distance, session 37.38.08.6-2.9-2.92.8-2.8-2.82.8-2.92.9-2.5
Stereotopy head waving bouts, day 30.30.30.6-0.5-0.40.7-0.5-0.60.6-0.6-0.0-0.7
Stereotopy head waving duration, day 30.10.10.50.10.2-0.10.10.1-0.10.1-0.7-0.2
Locomotion velocity, session 70.10.10.2-0.2-0.30.3-0.3-0.30.3-0.30.2-0.5
Locomotion distance, session 70.40.50.6-0.6-0.80.7-0.7-0.80.7-0.80.8-0.7
Stereotopy head waving bouts, day 70.10.10.60.40.4-0.20.20.3-0.20.3-0.8-0.1
Stereotopy head waving duration, day 70.10.10.3-0.1-0.10.2-0.2-0.00.2-0.1-0.3-0.6
Locomotion velocity, session 82.42.93.1-1.7-1.61.8-1.7-1.81.7-1.61.5-1.8
Locomotion distance, session 84.26.18.7-2.5-2.52.5-2.4-2.62.4-2.42.9-1.9
Degree of sensitization distance3.33.44.62.01.8-1.81.81.7-1.81.9-2.21.4
Degree of sensitization stereotypy0.10.10.20.30.3-0.30.20.4-0.20.3-0.5-0.0
Conditioned locomotion0.10.10.10.40.3-0.10.30.1-0.30.1-0.30.3
Cocaine response after cond. corrected1.51.71.9-1.3-1.31.4-1.3-1.41.3-1.31.3-1.3
Cocaine response after cond. not corrected2.22.52.8-1.6-1.51.6-1.5-1.71.5-1.61.7-1.4
Cocaine response before conditioning0.40.40.7-0.7-0.60.7-0.6-0.70.6-0.80.8-0.4
Saline control response1.21.51.9-1.2-1.11.3-1.2-1.41.2-1.41.3-1.0
Bone: connectivity density0.00.10.10.30.3-0.30.30.2-0.30.2-0.20.4
Bone: cortical apparent density0.10.20.4-0.3-0.40.4-0.4-0.40.4-0.40.1-0.6
Bone: cortical area0.10.10.3-0.3-0.30.3-0.4-0.20.4-0.30.0-0.5
Bone: cortical porosity1.92.14.01.71.4-1.41.31.4-1.31.4-2.00.8
Bone: cortical porosity1.92.13.71.71.4-1.31.31.5-1.31.4-1.90.9
Bone: cortical thickness0.10.20.6-0.3-0.30.4-0.4-0.20.5-0.4-0.3-0.8
Bone: cortical thickness0.91.11.4-1.2-1.20.9-1.0-0.91.0-0.91.2-1.0
Bone: cortical tissue density0.10.20.4-0.3-0.40.5-0.4-0.40.5-0.40.2-0.6
Condit. Reinf. active minus inactive responses1.82.04.31.41.5-1.31.31.5-1.31.3-2.10.9
Condit. Reinf. active-inactive response ratio1.82.04.01.41.4-1.21.41.5-1.31.2-2.01.0
Condit. Reinf. active responses0.30.31.10.60.6-0.40.50.5-0.50.5-1.10.2
Condit. Reinf. inactive responses1.21.41.7-1.1-1.21.2-1.2-1.31.2-1.11.3-1.0
Incentive salience index mean1.21.52.71.21.2-1.11.21.3-1.11.1-1.60.9
Condit. Reinf. lever presses0.40.50.50.70.6-0.70.70.7-0.70.7-0.60.7
Condit. Reinf. active minus inactive responses3.54.34.6-2.2-2.12.0-2.1-2.12.1-2.12.0-2.0
Condit. Reinf. active-inactive response ratio2.02.12.8-1.4-1.41.4-1.5-1.51.5-1.41.0-1.7
Condit. Reinf. active responses1.11.61.8-1.3-1.31.2-1.3-1.31.3-1.31.2-1.2
Condit. Reinf. inactive responses0.10.10.2-0.4-0.30.3-0.3-0.20.3-0.40.5-0.1
Condit. Reinf. lever presses1.72.32.7-1.5-1.51.6-1.5-1.51.5-1.71.5-1.3
Condit. Reinf. lever reinforcers received1.62.22.4-1.5-1.51.5-1.5-1.51.5-1.51.4-1.4
Conditioned reinforcement - actives2.62.62.9-1.6-1.71.7-1.7-1.61.6-1.61.5-1.6
Conditioned reinforcement - inactives0.20.30.5-0.1-0.50.7-0.5-0.60.5-0.6-0.0-0.7
Conditioned locomotion0.60.70.9-0.8-0.90.8-0.9-0.80.9-0.70.7-1.0
Patch foraging indifference point 0 sec4.67.49.2-2.5-2.83.0-2.7-2.92.7-2.92.2-2.7
Patch foraging indifference point AUC1.11.31.71.30.9-1.31.11.2-1.11.2-0.61.2
Delay disc. indifference point, 0s delay0.10.10.20.30.3-0.40.40.4-0.40.4-0.40.1
Delay disc. indifference point, 16s delay1.21.32.9-1.3-1.11.0-1.0-1.10.9-1.21.7-0.4
Delay disc. indifference point, 2s delay0.10.10.40.70.1-0.40.20.4-0.20.2-0.6-0.3
Delay disc. indifference point, 24s delay1.31.23.8-0.8-1.01.1-0.9-1.20.8-1.22.0-0.1
Delay disc. indifference point, 4s delay0.10.10.20.1-0.40.2-0.2-0.20.2-0.20.3-0.2
Delay disc. indifference point, 8s delay0.40.41.70.1-0.50.4-0.3-0.70.2-0.61.30.4
Indifference point function ln k4.66.47.6-2.6-2.42.8-2.5-2.72.5-2.72.0-2.5
Indifference point function log k4.66.47.6-2.6-2.42.8-2.5-2.72.5-2.72.0-2.5
Patch foraging total patch changes 0 sec5.58.810.5-2.8-3.03.2-3.0-3.13.0-3.22.4-3.0
Patch foraging total patch changes 12 sec0.00.00.10.3-0.2-0.10.00.1-0.10.00.30.2
Patch foraging total patch changes 18 sec0.00.00.10.2-0.20.1-0.0-0.00.0-0.3-0.2-0.1
Patch foraging total patch changes 24 sec0.70.91.1-0.6-1.11.0-0.9-1.00.9-0.90.9-0.9
Patch foraging total patch changes 6 sec0.91.31.9-0.9-1.41.1-1.2-1.01.1-1.21.1-1.2
Patch foraging time to switch 0 sec5.78.89.93.03.0-2.93.02.9-3.13.0-2.53.1
Patch foraging water rate 0 sec5.18.39.4-2.9-3.02.8-2.9-2.82.9-2.92.4-3.1
Patch foraging water rate 12 sec5.07.79.0-3.0-2.72.8-2.8-2.82.8-2.82.2-2.9
Patch foraging water rate 18 sec6.28.49.8-3.1-2.92.8-2.9-2.82.9-2.82.8-2.9
Patch foraging water rate 24 sec2.63.65.5-2.0-1.91.8-2.0-1.82.0-1.81.4-2.3
Patch foraging water rate 6 sec13.619.922.3-4.7-4.44.5-4.5-4.64.5-4.34.1-4.5
Seeking ratio, delayed vs. immediate footshock1.31.51.91.41.0-1.41.21.3-1.21.3-1.01.1
Distance traveled before self-admin2.12.22.6-1.6-1.51.6-1.5-1.51.5-1.41.5-1.3
Distance traveled after self-admin1.51.61.8-1.3-1.21.2-1.3-1.31.3-1.31.3-1.2
Extensor digitorum longus weight4.116.017.33.94.0-4.14.04.1-3.94.2-4.13.6
Bone: elastic displacement1.41.61.81.21.3-1.31.31.3-1.31.1-1.21.2
Bone: elastic work0.60.81.11.00.9-0.90.91.0-0.90.7-0.71.0
Bone: endosteal estimation0.30.61.2-0.7-0.80.7-0.7-0.90.7-0.91.1-0.3
Bone: endosteal perimeter0.00.00.20.30.1-0.10.10.1-0.20.10.30.4
Epididymis fat weight0.00.00.30.10.2-0.20.10.2-0.0-0.0-0.5-0.2
Delta time in closed arm before/after self-admin3.73.65.82.01.9-1.92.01.7-2.01.6-1.22.4
Delta time in open arm before/after self-admin0.00.00.0-0.00.20.10.1-0.1-0.10.1-0.10.1
Diff in mean of infusions in LGA sessions0.30.30.40.60.6-0.50.60.4-0.60.5-0.60.5
Delay discount exponential model param0.80.82.30.41.0-0.80.70.9-0.71.0-1.50.3
Extinction: sum of active levers before priming1.51.52.61.41.2-0.91.31.0-1.31.0-0.91.6
Active lever presses in extinction session 62.22.12.61.61.4-1.41.51.4-1.51.4-1.21.6
Bone: final force0.71.11.5-1.1-1.11.1-1.0-1.01.0-1.11.2-0.8
Bone: final moment0.91.41.7-1.2-1.21.2-1.2-1.11.2-1.31.3-1.0
Food consumed during 24 hour testing period0.81.01.4-1.0-1.01.0-1.0-1.01.1-1.00.7-1.2
Glucose1.01.53.61.21.2-1.21.11.4-1.01.2-1.90.6
Heart weight0.40.60.80.30.8-0.80.80.9-0.80.9-0.80.7
Delay discount hyperbolic model param0.50.51.40.30.9-0.60.60.8-0.60.8-1.20.3
Intermittent access intake day 1-15 change0.10.10.3-0.3-0.00.4-0.2-0.20.2-0.3-0.4-0.6
Intermittent access intake escalation0.20.20.6-0.5-0.10.5-0.3-0.30.4-0.4-0.4-0.8
Intermittent access intake escalation 20.00.00.20.10.3-0.00.10.1-0.10.0-0.4-0.2
Intermitt. access day 1 inactive lever presses2.83.03.61.91.8-1.51.71.7-1.71.7-1.91.6
Intermitt. access day 15 inactive lever presses3.03.33.71.91.8-1.71.81.8-1.81.6-1.91.9
Intermitt. access escalation Index0.20.20.6-0.8-0.30.3-0.4-0.30.4-0.40.5-0.2
Intermittent access day 1 total infusions0.70.91.2-1.0-1.01.1-1.0-0.81.0-0.90.7-0.9
Intermittent access day 15 total infusions1.61.82.7-1.3-1.21.6-1.3-1.31.4-1.40.4-1.6
Intermittent access terminal intake (last 3 days)0.80.81.3-1.0-0.91.1-0.9-0.80.9-0.90.4-1.0
Intermittent access total infusions1.92.12.8-1.5-1.41.7-1.5-1.41.5-1.50.9-1.6
Intermittent access day 1 locomotion2.22.33.2-1.8-1.51.6-1.6-1.41.6-1.41.1-1.7
Intermittent access day 15 total locomotion1.71.83.3-1.1-1.31.5-1.4-1.31.5-1.30.5-1.8
Intermittent access total locomotion4.55.16.5-2.3-2.32.4-2.3-2.22.4-2.11.6-2.5
Intermittent access standard deviation0.50.50.80.70.7-0.80.70.9-0.70.8-0.90.5
Left kidney weight1.02.83.1-1.7-1.61.7-1.7-1.81.7-1.71.6-1.7
Right kidney weight0.30.71.0-0.8-0.90.8-0.9-0.90.9-0.81.0-0.8
Cocaine induced anxiety1.01.22.6-0.7-1.21.1-1.0-1.11.0-1.11.6-0.5
Post-drug Anxiety1.51.63.0-1.3-1.31.1-1.2-1.41.2-1.41.7-0.8
Baseline Anxiety0.00.00.1-0.3-0.00.0-0.1-0.10.1-0.1-0.0-0.1
Tail length8.024.327.0-4.5-4.95.1-5.0-5.15.1-5.24.4-5.1
Length with tail11.843.047.0-6.4-6.66.6-6.7-6.66.7-6.96.0-6.5
Length without tail6.915.216.4-4.1-4.03.8-4.0-3.84.0-4.03.6-3.8
Times rat made contact with spout0.40.40.60.60.7-0.70.70.8-0.70.7-0.60.6
Lifetime Intake1.71.92.6-1.3-1.51.6-1.4-1.31.4-1.40.9-1.5
Liver weight, left0.40.62.5-0.5-0.40.7-0.7-0.50.8-0.6-0.7-1.6
Liver weight, right0.00.10.10.20.4-0.20.30.3-0.30.3-0.20.3
Locomotor activity0.30.51.1-0.8-0.80.7-0.7-0.80.6-0.71.1-0.4
Locomotor testing distance0.30.41.00.60.7-0.50.70.4-0.80.6-0.31.0
Locomotor testing rearing0.20.30.60.30.7-0.40.60.4-0.60.3-0.30.8
Locomotion in novel chamber0.91.12.20.71.2-1.11.11.0-1.11.0-0.71.5
Locomotion in novel chamber post-restriction0.10.10.4-0.00.1-0.20.20.1-0.30.10.30.6
Fecal boli incidents, locomotor time 11.92.12.81.31.5-1.41.61.4-1.61.3-1.21.7
Change in fecal boli incidents, locomotor task0.10.10.30.4-0.0-0.50.00.50.00.6-0.2-0.0
Time >=10cm from walls, locomotor time 11.61.62.01.31.3-1.21.31.2-1.31.2-1.41.2
Bouts of movement, locomotor time 10.30.30.60.80.6-0.40.70.3-0.70.3-0.40.7
Total resting periods, locomotor time 10.10.10.20.30.2-0.10.30.0-0.40.00.20.5
Rest time, locomotor task time 11.61.82.31.11.4-1.41.41.3-1.41.4-0.91.5
Distance moved, locomotor task time 11.61.72.6-1.1-1.41.3-1.5-1.21.5-1.30.9-1.6
Vertical activity count, locomotor time 11.31.32.7-0.9-1.30.9-1.3-0.91.3-1.00.9-1.6
Time >=10cm from walls, locomotor time 20.80.81.31.00.8-0.90.90.9-0.91.0-0.61.1
Bouts of movement, locomotor time 20.30.30.9-0.4-0.60.4-0.4-0.50.4-0.50.9-0.1
Total resting periods, locomotor time 20.00.00.20.1-0.1-0.10.10.1-0.10.00.40.3
Rest time, locomotor task time 23.94.55.22.12.3-2.02.22.1-2.12.1-2.12.0
Distance moved, locomotor task time 22.02.43.1-1.7-1.61.4-1.6-1.51.6-1.31.5-1.5
Vertical activity count, locomotor time 20.50.51.9-0.8-0.80.4-0.8-0.40.8-0.30.2-1.4
Light reinforcement 12.24.05.5-1.8-1.92.1-2.0-2.12.0-2.01.5-2.3
Light reinforcement 20.20.20.40.60.6-0.40.40.4-0.40.3-0.60.2
Bone: marrow area0.30.61.2-0.7-0.70.7-0.7-0.90.6-0.81.1-0.3
Bone: maximum diameter0.50.81.10.90.9-1.00.91.0-0.90.9-0.80.9
Bone: maximum force0.10.20.5-0.5-0.50.5-0.5-0.40.4-0.60.7-0.2
Bone: maximum moment0.30.50.7-0.6-0.70.7-0.7-0.60.6-0.80.8-0.4
Mean time between licks in bursts0.10.10.20.30.3-0.30.30.3-0.30.3-0.50.3
Mean num. licks in bursts2.12.52.9-1.6-1.61.6-1.6-1.61.6-1.61.4-1.7
Cd content in liver0.40.50.6-0.8-0.80.6-0.7-0.70.7-0.40.8-0.7
Co content in liver0.20.30.7-0.5-0.50.5-0.4-0.60.4-0.70.8-0.0
Cu content in liver0.20.20.6-0.4-0.30.5-0.5-0.50.5-0.6-0.1-0.7
Fe content in liver1.41.72.4-1.3-1.21.3-1.3-1.31.4-1.30.8-1.6
K content in liver3.13.06.3-2.0-1.91.5-1.7-1.71.6-1.32.5-1.1
Mg content in liver0.70.83.1-1.0-0.90.6-0.7-0.70.6-0.31.8-0.1
Mn content in liver0.30.30.5-0.6-0.60.6-0.6-0.40.6-0.50.5-0.7
Na content in liver0.20.20.4-0.5-0.50.4-0.5-0.30.5-0.50.6-0.4
Rb content in liver0.81.01.8-0.9-1.01.1-1.0-0.91.0-1.30.8-1.0
Se content in liver0.10.20.30.40.4-0.50.40.4-0.40.5-0.50.3
Sr content in liver2.11.93.61.31.3-1.41.51.3-1.51.3-0.71.9
Zn content in liver0.00.00.2-0.1-0.10.1-0.0-0.4-0.0-0.10.40.2
Bone: minimum diameter1.93.63.9-1.8-1.92.0-1.9-1.91.9-1.91.8-1.8
Time in familiar zone, hab. session 14.44.14.8-2.1-2.21.9-2.1-1.92.1-1.91.9-2.1
Time in novel zone, hab. session 16.16.06.62.52.6-2.32.52.3-2.52.3-2.42.5
Total zone transitions, hab. session 10.00.00.2-0.1-0.20.0-0.2-0.00.1-0.00.50.0
Total locomotion distance, hab. session 10.10.20.9-0.3-0.30.2-0.3-0.30.2-0.21.00.2
Locomotion velocity, hab. session 10.10.10.6-0.2-0.30.2-0.2-0.30.2-0.20.80.1
Time in familiar zone, hab. session 21.51.61.9-1.4-1.21.2-1.3-1.11.3-1.11.3-1.3
Time in novel zone, hab. session 21.91.92.31.51.3-1.31.41.3-1.41.3-1.51.4
Total zone transitions, hab. session 20.10.10.2-0.4-0.40.3-0.4-0.30.4-0.30.5-0.4
Total locomotion distance, hab. session 20.00.10.30.00.1-0.20.10.1-0.10.20.50.4
Locomotion velocity, hab. session 20.10.10.6-0.3-0.30.2-0.3-0.30.2-0.10.80.0
Novel to familiar place preference ratio2.02.12.61.61.5-1.41.51.3-1.51.3-1.41.4
Novelty place preference1.51.52.01.41.3-1.11.31.1-1.31.1-1.31.2
Time in novel zone, NPP test1.71.72.11.51.4-1.21.41.2-1.41.2-1.41.2
Total zone transitions, NPP test1.42.02.2-1.5-1.41.3-1.5-1.31.5-1.41.5-1.4
Total locomotion distance, NPP test0.10.20.5-0.5-0.30.3-0.4-0.40.4-0.30.7-0.1
Locomotion velocity, NPP test0.60.91.4-1.0-0.90.9-1.0-1.00.9-0.91.2-0.7
Intraocular pressure4.25.811.12.52.6-2.12.42.3-2.32.2-3.31.7
Delta distance traveled before/after self-admin0.40.50.6-0.6-0.70.5-0.7-0.70.6-0.70.8-0.7
Delta ambulatory time before/after self-admin0.50.50.9-0.7-0.80.6-0.7-0.70.7-0.80.9-0.7
Parametrial fat weight0.00.10.30.30.2-0.20.10.3-0.10.1-0.5-0.1
Pavlov. Cond. lever latency0.10.10.30.20.4-0.30.20.3-0.20.3-0.5-0.0
Pavlov. Cond. magazine entry latency2.53.26.1-1.9-2.01.6-1.7-1.81.7-1.72.5-1.2
Pavlov. Cond. change in total contacts3.53.84.9-2.0-2.11.9-1.9-1.91.9-1.92.2-1.6
Pavlov. Cond. index score0.70.92.1-0.9-1.10.8-0.9-0.90.8-0.91.4-0.4
Pavlov. Cond. latency score0.30.31.1-0.5-0.70.5-0.5-0.50.5-0.51.0-0.1
Pavlov. Cond. lever contacts0.50.61.4-0.8-0.90.7-0.8-0.70.7-0.71.2-0.4
Pavlov. Cond. magazine entry number2.83.47.41.92.1-1.61.71.7-1.71.7-2.71.0
Pavlov. Cond. intertrial magazine entries5.56.79.62.62.7-2.52.62.6-2.52.5-3.12.1
Pavlov. Cond. lever-magazine prob. diff.0.91.12.3-1.1-1.21.0-1.0-1.01.0-1.01.5-0.6
Pavlov. Cond. response bias2.53.15.3-1.8-2.01.6-1.7-1.71.6-1.62.3-1.2
Pavlov. Cond. lever latency1.92.63.11.61.6-1.61.61.7-1.51.7-1.81.3
Pavlov. Cond. magazine entry latency1.11.32.6-1.2-1.21.1-1.1-1.21.0-1.11.6-0.6
Pavlov. Cond. change in total contacts5.37.28.1-2.8-2.72.6-2.7-2.82.6-2.82.9-2.3
Pavlov. Cond. index score2.73.54.9-1.9-1.91.8-1.8-1.91.8-2.02.2-1.4
Pavlov. Cond. latency score2.83.55.0-1.9-1.91.9-1.8-2.01.8-2.02.2-1.4
Pavlov. Cond. lever contacts2.02.73.0-1.7-1.61.7-1.6-1.71.6-1.71.7-1.4
Pavlov. Cond. magazine entry number2.02.54.71.61.6-1.41.51.6-1.51.6-2.21.0
Pavlov. Cond. intertrial magazine entries0.10.10.3-0.1-0.10.2-0.2-0.10.2-0.2-0.5-0.6
Pavlov. Cond. lever-magazine prob. diff.2.93.75.1-2.0-1.91.9-1.9-2.01.8-2.02.3-1.4
Pavlov. Cond. response bias1.72.32.9-1.5-1.51.5-1.5-1.51.5-1.51.7-1.2
Time in closed arm before self-admin0.00.00.1-0.3-0.20.2-0.2-0.30.2-0.10.2-0.3
Time in closed arm after self-admin0.50.50.70.70.6-0.90.70.8-0.70.8-0.40.9
Time in open arm before self-admin0.10.10.2-0.2-0.30.2-0.3-0.20.3-0.30.5-0.1
Time in open arm after self-admin0.30.30.50.60.7-0.40.60.4-0.60.5-0.70.5
Bone: periosteal estimation0.20.30.5-0.5-0.60.6-0.6-0.60.6-0.70.6-0.5
Bone: periosteal perimeter0.00.10.2-0.1-0.30.3-0.2-0.20.2-0.30.40.1
Bone: post-yield work0.00.00.0-0.10.1-0.00.0-0.0-0.00.0-0.2-0.1
Progressive ratio test 1 active lever presses0.80.91.1-0.9-1.01.0-1.0-0.91.0-0.90.6-0.9
Progressive ratio test 1 breakpoint1.01.01.3-1.0-1.11.1-1.1-1.01.1-1.00.8-0.9
Progressive ratio test 1 inactive lever presses0.50.50.8-0.6-0.80.9-0.7-0.70.7-0.80.4-0.7
Progressive ratio test 2 active lever presses0.20.20.4-0.5-0.50.6-0.5-0.40.5-0.50.1-0.6
Progressive ratio test 2 breakpoint0.10.20.3-0.4-0.40.5-0.4-0.30.4-0.40.0-0.5
Progressive ratio test 2 inactive lever presses0.10.20.4-0.2-0.30.6-0.3-0.30.4-0.4-0.3-0.6
Incentive Sensitization - Responses0.60.60.8-0.7-0.70.9-0.7-0.80.7-0.90.5-0.8
Incentive Sensitization - Breakpoint0.30.30.5-0.6-0.50.7-0.5-0.60.6-0.70.3-0.7
Sum of active levers in priming session hrs 5-61.11.11.51.10.9-1.01.01.2-1.01.1-1.10.9
Progressive ratio0.00.00.1-0.30.1-0.10.10.0-0.10.0-0.10.2
Food seeking constrained by brief footshock2.42.93.4-1.8-1.81.7-1.7-1.71.7-1.71.8-1.5
Seeking ratio, punishment vs. effort0.60.81.1-0.6-1.00.9-0.9-0.80.9-0.80.9-1.1
Retroperitoneal fat weight0.82.84.31.91.7-1.71.51.7-1.51.6-2.11.0
Reaction time number correct8.912.915.0-3.9-3.63.6-3.6-3.63.6-3.53.3-3.6
Reaction time mean minus median0.10.10.1-0.3-0.30.2-0.3-0.20.3-0.40.4-0.1
Reaction time mean minus median AUC0.30.40.5-0.7-0.70.6-0.7-0.50.7-0.70.6-0.6
Reaction time num false alarms0.60.81.31.20.7-0.90.91.0-0.90.8-1.00.8
Reaction time num false alarms AUC1.11.52.01.41.1-1.21.21.3-1.21.1-1.41.0
Reaction time trials correct on left8.912.915.0-3.9-3.63.6-3.6-3.63.6-3.53.3-3.6
Reaction time trials on left9.113.115.1-3.9-3.63.6-3.6-3.63.6-3.53.3-3.6
Reaction time mean1.52.02.41.51.5-1.41.41.4-1.41.3-1.31.5
Reaction time mean AUC1.31.72.01.41.3-1.31.31.3-1.31.2-1.11.4
Median of all reaction times2.63.54.22.11.9-1.91.91.9-1.91.8-1.71.9
Reaction time omissions0.10.10.5-0.2-0.30.3-0.4-0.20.4-0.3-0.2-0.7
Reaction time false alarm rate6.18.510.33.22.8-2.92.93.0-2.92.8-3.02.7
Reaction time premature initiation rate3.95.26.2-2.3-2.42.2-2.3-2.32.3-2.22.5-2.0
Reaction time premature initiations11.416.117.5-4.2-4.13.9-4.0-4.04.0-3.94.1-3.7
Std. dev. reaction times0.10.10.10.30.3-0.40.30.4-0.30.2-0.30.3
Reaction time trials completed9.113.115.1-3.9-3.63.6-3.6-3.63.6-3.53.3-3.6
Reaction time trials AUC8.311.913.5-3.7-3.53.5-3.5-3.53.5-3.43.1-3.5
Run reversals in cocaine runway, females0.60.50.70.80.8-0.80.80.6-0.80.6-0.60.8
Run reversals in cocaine runway, males0.10.10.9-0.1-0.3-0.1-0.00.0-0.00.00.90.5
Latency to leave start box in cocaine runway2.32.52.91.51.6-1.71.61.6-1.61.6-1.41.5
Latency to leave start box in cocaine runway, F0.30.40.60.70.6-0.70.60.6-0.60.6-0.60.4
Latency to leave start box in cocaine runway, M2.42.33.01.11.5-1.71.61.6-1.61.6-1.21.7
Std. dev. time between licks in bursts1.01.21.51.11.1-1.21.11.2-1.11.1-0.81.2
Total sessions with >9 infusions0.70.81.2-1.1-1.10.9-0.9-0.70.9-0.80.8-0.8
Short access day 1 total inactive lever presses0.10.10.20.20.00.3-0.1-0.20.1-0.2-0.5-0.4
Short access day 10 total inactive lever presses0.40.51.00.70.7-0.70.80.5-0.80.5-0.51.0
Short access day 1 total infusions1.11.21.6-1.1-1.11.3-1.1-1.01.1-1.00.7-1.2
Short access day 10 total infusions1.11.21.7-0.9-1.31.3-1.2-1.01.2-1.10.9-1.1
Short access total infusions1.61.82.2-1.2-1.51.5-1.4-1.21.4-1.31.0-1.4
Short access day 1 locomotion0.20.30.4-0.6-0.50.6-0.6-0.30.6-0.30.1-0.7
Short access day 10 total locomotion0.00.00.2-0.10.10.10.00.10.00.1-0.5-0.2
Short access total locomotion1.41.52.5-1.4-1.21.3-1.3-1.01.4-1.00.5-1.6
One hour access (0.3 mA shock)0.91.01.9-1.0-1.01.1-1.1-0.91.1-0.90.5-1.4
Compulsive drug intake0.20.20.30.10.4-0.50.40.4-0.40.5-0.40.3
One hour access (shock baseline)1.92.22.9-1.3-1.51.7-1.5-1.41.6-1.51.1-1.7
Social response proportion0.10.10.1-0.00.3-0.30.30.2-0.30.3-0.30.3
Social responses1.62.03.9-1.6-1.51.3-1.3-1.51.3-1.22.0-0.9
Social time0.00.00.10.20.20.10.1-0.0-0.1-0.1-0.3-0.1
Soleus weight0.20.71.90.70.9-0.60.70.8-0.70.7-1.40.4
Bone: stiffness0.40.61.1-0.7-0.80.8-0.7-0.70.7-0.81.1-0.4
Tibialis anterior weight2.48.29.02.92.8-3.02.92.9-2.83.0-2.82.6
Time to tail flick, vehicle, before self-admin4.44.55.3-2.0-2.12.3-2.1-2.32.1-2.31.7-2.2
Time to tail flick, vehicle, after self-admin2.02.23.3-1.6-1.61.5-1.4-1.51.4-1.41.8-1.0
Time to tail flick, test, before self-admin0.10.10.3-0.2-0.30.4-0.3-0.30.4-0.30.1-0.6
Time to tail flick, test, after self-admin0.91.02.50.80.9-1.10.81.1-0.71.1-1.60.1
Delta time to tail flick, vehicle, before/after SA1.01.01.60.90.9-1.11.01.1-1.01.1-0.41.3
Delta time to tail flick, test, before/after SA0.10.10.20.10.2-0.50.20.3-0.20.4-0.30.1
Tibia length6.217.521.6-4.1-4.04.5-4.2-4.34.2-4.63.2-4.5
Ambulatory time before self-admin0.70.70.9-0.6-0.80.9-0.9-0.90.9-0.90.9-0.7
Ambulatory time after self-admin1.01.11.5-1.0-0.91.0-1.0-1.11.0-1.11.2-0.8
Bone: tissue strength1.11.11.61.31.1-0.91.01.0-1.00.8-1.11.0
Total heroin consumption1.41.62.20.71.3-1.31.31.4-1.31.5-1.41.2
Bone: trabecular number0.00.00.10.00.1-0.20.10.1-0.10.00.10.3
Bone: trabecular spacing0.20.31.20.50.3-0.50.30.6-0.20.5-1.1-0.4
Bone: trabecular thickness0.91.02.01.01.0-0.91.10.9-1.10.9-0.51.4
Bone: trabecular tissue density2.43.33.91.82.0-1.81.81.9-1.81.8-1.71.7
Water consumed over 24 hours0.60.80.90.81.0-0.90.91.0-0.90.9-0.90.8
Number of responses in last shaping day0.50.50.80.90.7-0.50.60.8-0.60.7-0.90.6