Sgsm3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	mRNA stability	Sgsm3	0.02	0.02	4.5e-03	0	0.01	0	0	1.8e-01	2.2e-02	2.7e-01	2.3e-01
2	Liver	gene expression	Sgsm3	0.1	0.05	1.1e-09	0.09	0.08	0.07	0.07	9.6e-10	2.9e-09	2.3e-08	1.7e-08
3	NAcc	mRNA stability	Sgsm3	0.03	0.02	6.5e-05	0.03	0.02	0.03	0.03	2.3e-05	3.9e-04	9.4e-05	9.9e-05
4	NAcc	gene expression	Sgsm3	0.07	0.04	2.0e-08	0.05	0.05	0.05	0.05	1.8e-08	2.0e-08	2.0e-08	2.2e-08
5	Brain	gene expression	Sgsm3	0.08	0.05	4.3e-06	0.06	0.07	0.06	0.07	1.5e-06	2.7e-07	1.1e-06	8.8e-07
6	LHb	gene expression	Sgsm3	0.4	0.14	4.0e-08	0.31	0.35	0.28	0.35	3.9e-08	4.2e-09	2.2e-07	3.1e-09
7	pVTA	gene expression	Sgsm3	0.32	0.11	0.0e+00	0.35	0.34	0.33	0.35	2.9e-29	1.7e-28	4.7e-27	2.5e-29
8	RMTg	gene expression	Sgsm3	0.22	0.15	4.1e-03	0.1	0.07	0.04	0.06	1.7e-03	5.8e-03	4.2e-02	1.2e-02
9	Adipose	gene expression	Sgsm3	0.07	0.04	5.6e-07	0.03	0.04	0.04	0.05	5.8e-04	1.1e-05	7.2e-05	6.4e-06
10	pVTA	mRNA stability	Sgsm3	0.12	0.08	5.3e-06	0.06	0.07	0.06	0.06	2.7e-05	4.1e-06	1.6e-05	9.3e-06
11	Liver	alternative TSS	XM_017594989.3	0.02	0.02	5.6e-03	0.03	0.01	0.02	0.02	7.8e-04	9.9e-03	1.8e-03	1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.2	0.3	0.7	-0.1	-0.4	-0.4	0.5	0.5	0.5	0.6	0.6	-0.9	-0.6	0.3
Area under the delay curve	0.7	0.8	1.3	0.3	-1.0	-1.0	0.9	1.1	0.9	0.8	0.8	-1.2	-0.9	-0.3
BMI with tail	0.2	0.6	3.6	-1.9	-0.6	-0.6	0.6	0.4	0.5	0.5	0.6	0.1	-0.5	1.1
BMI without tail	0.0	0.1	1.2	-0.4	-0.2	-0.2	0.2	-0.1	-0.0	0.1	0.1	-0.1	-0.2	1.1
Body weight	0.4	2.0	6.9	-2.6	-1.2	-1.2	1.2	1.1	1.1	1.2	1.2	-0.2	-1.2	2.0
Weight adjusted by age	0.5	0.7	1.1	0.7	1.0	1.0	-1.0	-0.8	-0.9	-0.9	-0.9	0.9	0.6	-0.1
Bone surface	0.3	0.6	1.2	0.2	-0.7	-0.7	0.7	0.8	0.8	0.8	0.8	-1.1	-1.0	0.1
Bone volume	0.2	0.4	0.7	-0.2	-0.6	-0.6	0.6	0.7	0.7	0.7	0.7	-0.9	-0.7	0.1
Breakpoint value in progressive ratio session	0.4	0.4	0.6	-0.6	-0.6	-0.6	0.6	0.7	0.7	0.8	0.8	-0.8	-0.6	0.4
Number of licking bursts	0.1	0.2	1.5	1.2	0.3	0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.2	0.1	0.2
Context. condit. distance diff. score	1.1	1.3	4.5	-1.7	0.8	0.8	-0.9	-1.0	-0.9	-0.9	-0.9	2.1	0.9	-0.9
Locomotion velocity, session 1	0.5	0.6	1.0	0.1	-0.8	-0.8	0.7	0.9	0.8	0.7	0.7	-0.8	-1.0	0.1
Locomotion distance, session 1	0.3	0.4	2.6	1.6	-0.3	-0.3	0.3	0.5	0.4	0.3	0.3	-0.9	-0.5	-0.5
Locomotion velocity, session 2	0.4	0.4	0.5	-0.7	-0.6	-0.6	0.7	0.7	0.7	0.7	0.7	-0.5	-0.6	0.6
Locomotion distance, session 2	1.6	2.2	5.0	0.9	-1.4	-1.4	1.4	1.5	1.4	1.4	1.4	-2.2	-1.6	1.4
Locomotion velocity, session 3	1.4	1.6	2.9	0.6	1.3	1.3	-1.4	-1.3	-1.3	-1.4	-1.4	1.7	1.1	-0.9
Locomotion distance, session 3	2.7	2.9	4.2	2.1	1.8	1.8	-1.8	-1.6	-1.7	-1.8	-1.8	1.6	1.4	-1.3
Stereotopy head waving bouts, day 3	1.7	2.0	2.2	-1.5	-1.5	-1.5	1.4	1.4	1.5	1.4	1.4	-1.3	-1.3	1.4
Stereotopy head waving duration, day 3	2.4	2.8	5.9	-2.4	-1.7	-1.7	1.7	1.6	1.6	1.7	1.7	-1.1	-1.4	1.7
Locomotion velocity, session 7	0.1	0.1	0.4	-0.2	0.3	0.3	-0.3	-0.3	-0.3	-0.3	-0.3	0.6	0.2	-0.3
Locomotion distance, session 7	0.2	0.3	0.5	-0.2	-0.6	-0.6	0.6	0.7	0.6	0.6	0.6	-0.5	-0.6	0.4
Stereotopy head waving bouts, day 7	0.5	0.6	1.7	-0.7	0.7	0.7	-0.7	-0.7	-0.7	-0.7	-0.7	1.3	0.7	-0.5
Stereotopy head waving duration, day 7	0.8	1.0	2.3	-0.8	0.9	0.9	-0.9	-1.0	-0.9	-0.9	-0.9	1.5	1.2	-0.9
Locomotion velocity, session 8	1.0	1.2	2.3	-1.5	-1.1	-1.1	1.0	1.1	1.1	1.0	1.0	-0.6	-1.3	1.2
Locomotion distance, session 8	0.2	0.4	1.1	-0.4	0.5	0.5	-0.6	-0.6	-0.6	-0.6	-0.6	1.0	0.6	-0.4
Degree of sensitization distance	3.2	3.3	6.2	-2.5	-1.9	-1.9	1.9	1.7	1.8	1.9	1.9	-1.4	-1.4	1.4
Degree of sensitization stereotypy	0.7	0.8	2.0	-0.5	0.9	0.9	-0.8	-0.9	-0.9	-0.8	-0.8	1.4	0.8	-0.7
Conditioned locomotion	0.0	0.0	0.3	-0.5	-0.0	-0.0	0.0	-0.0	-0.1	-0.1	-0.1	0.4	0.2	-0.1
Cocaine response after cond. corrected	0.3	0.3	0.4	-0.6	-0.7	-0.7	0.7	0.6	0.6	0.6	0.6	-0.4	-0.4	0.3
Cocaine response after cond. not corrected	0.1	0.1	0.2	-0.4	-0.4	-0.4	0.4	0.3	0.3	0.3	0.3	-0.2	-0.1	0.4
Cocaine response before conditioning	0.4	0.5	0.7	0.7	0.8	0.8	-0.8	-0.8	-0.8	-0.8	-0.8	0.5	0.8	-0.2
Saline control response	1.1	1.4	1.9	0.7	1.1	1.1	-1.1	-1.2	-1.3	-1.3	-1.3	1.3	1.4	-1.1
Bone: connectivity density	0.2	0.3	0.5	-0.2	-0.5	-0.5	0.6	0.5	0.6	0.6	0.6	-0.7	-0.7	0.5
Bone: cortical apparent density	1.8	2.5	3.4	1.8	1.7	1.7	-1.7	-1.7	-1.6	-1.7	-1.7	1.2	1.3	-1.1
Bone: cortical area	2.1	3.2	4.2	-2.1	-1.7	-1.7	1.8	1.8	1.9	1.9	1.9	-1.4	-1.7	1.4
Bone: cortical porosity	0.3	0.3	1.3	-1.1	-0.6	-0.6	0.5	0.4	0.5	0.5	0.5	-0.2	-0.2	-0.0
Bone: cortical porosity	1.2	1.4	3.6	-1.9	-1.2	-1.2	1.2	1.1	1.2	1.2	1.2	-0.7	-0.8	0.5
Bone: cortical thickness	0.8	1.4	1.8	-1.1	-1.1	-1.1	1.1	1.1	1.2	1.2	1.2	-1.1	-1.4	1.3
Bone: cortical thickness	2.3	2.7	4.1	-1.0	-1.5	-1.5	1.6	1.7	1.7	1.7	1.7	-1.6	-1.8	2.0
Bone: cortical tissue density	1.7	2.4	3.2	1.8	1.6	1.6	-1.6	-1.6	-1.6	-1.7	-1.7	1.2	1.2	-1.1
Condit. Reinf. active minus inactive responses	0.1	0.1	0.2	0.4	-0.2	-0.2	0.2	0.2	0.2	0.2	0.2	-0.4	-0.4	0.3
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.4	0.1	0.5	0.5	-0.5	-0.4	-0.4	-0.5	-0.5	0.6	0.4	-0.3
Condit. Reinf. active responses	0.2	0.3	1.7	1.3	0.3	0.3	-0.4	-0.4	-0.4	-0.4	-0.4	-0.3	0.4	-0.3
Condit. Reinf. inactive responses	0.6	0.7	2.7	1.6	0.7	0.7	-0.7	-0.7	-0.8	-0.7	-0.7	-0.0	0.9	-1.0
Incentive salience index mean	0.1	0.1	0.4	0.6	-0.1	-0.1	0.1	0.1	0.1	0.1	0.1	-0.5	-0.3	0.2
Condit. Reinf. lever presses	0.1	0.1	0.6	0.7	-0.1	-0.1	0.0	0.0	-0.0	0.0	0.0	-0.5	-0.1	0.1
Condit. Reinf. active minus inactive responses	1.3	1.6	2.5	-0.2	-1.3	-1.3	1.3	1.5	1.4	1.4	1.4	-1.6	-1.6	0.6
Condit. Reinf. active-inactive response ratio	2.0	2.3	3.1	-0.8	-1.5	-1.5	1.5	1.6	1.6	1.6	1.6	-1.7	-1.8	1.2
Condit. Reinf. active responses	0.9	1.2	1.9	-0.5	-1.1	-1.1	1.1	1.3	1.3	1.2	1.2	-1.1	-1.4	0.5
Condit. Reinf. inactive responses	0.1	0.2	0.3	-0.4	-0.4	-0.4	0.4	0.6	0.5	0.4	0.4	-0.1	-0.6	0.1
Condit. Reinf. lever presses	0.1	0.2	0.4	0.3	-0.5	-0.5	0.5	0.4	0.3	0.3	0.3	-0.6	-0.4	-0.0
Condit. Reinf. lever reinforcers received	0.8	1.2	1.7	-0.5	-1.1	-1.1	1.1	1.2	1.2	1.2	1.2	-1.2	-1.3	0.5
Conditioned reinforcement - actives	0.2	0.4	0.6	-0.4	-0.7	-0.7	0.6	0.8	0.7	0.6	0.6	-0.5	-0.7	0.5
Conditioned reinforcement - inactives	1.7	2.5	4.5	-0.4	-1.6	-1.6	1.6	1.8	1.7	1.7	1.7	-2.1	-1.6	1.1
Conditioned locomotion	2.2	2.9	3.3	-1.8	-1.7	-1.7	1.7	1.8	1.8	1.8	1.8	-1.5	-1.7	1.6
Patch foraging indifference point 0 sec	0.1	0.2	0.8	0.1	-0.4	-0.4	0.4	0.3	0.4	0.4	0.4	-0.9	-0.5	0.6
Patch foraging indifference point AUC	0.2	0.3	0.9	1.0	-0.4	-0.4	0.4	0.6	0.4	0.3	0.3	-0.6	-0.6	0.0
Delay disc. indifference point, 0s delay	1.3	1.4	2.3	-1.5	-1.4	-1.4	1.4	1.2	1.2	1.3	1.3	-0.8	-0.7	0.3
Delay disc. indifference point, 16s delay	0.3	0.3	0.9	0.9	-0.1	-0.1	0.5	0.6	0.4	0.3	0.3	-1.0	-0.5	-0.5
Delay disc. indifference point, 2s delay	0.8	0.9	1.5	-0.2	-1.2	-1.2	1.1	1.0	1.0	0.9	0.9	-1.0	-0.9	0.1
Delay disc. indifference point, 24s delay	0.8	0.9	1.9	0.3	-0.7	-0.7	1.0	1.2	1.1	0.9	0.9	-1.2	-1.4	-0.0
Delay disc. indifference point, 4s delay	1.2	1.3	2.7	-0.1	-1.7	-1.7	1.0	1.1	1.1	1.1	1.1	-1.3	-1.1	0.4
Delay disc. indifference point, 8s delay	0.3	0.3	0.7	0.7	-0.6	-0.6	0.4	0.6	0.4	0.4	0.4	-0.8	-0.5	-0.5
Indifference point function ln k	0.4	0.7	1.4	-0.8	0.9	0.9	-0.9	-1.0	-0.8	-0.7	-0.7	1.2	0.8	-0.4
Indifference point function log k	0.4	0.7	1.4	-0.8	0.9	0.9	-0.9	-1.0	-0.8	-0.7	-0.7	1.2	0.8	-0.4
Patch foraging total patch changes 0 sec	0.1	0.2	0.8	0.3	-0.3	-0.3	0.4	0.3	0.3	0.4	0.4	-0.9	-0.4	0.5
Patch foraging total patch changes 12 sec	0.3	0.4	0.6	-0.1	-0.7	-0.7	0.7	0.7	0.6	0.6	0.6	-0.8	-0.7	0.5
Patch foraging total patch changes 18 sec	1.7	2.5	4.1	-0.5	-1.7	-1.7	1.7	1.8	1.7	1.7	1.7	-2.0	-1.6	0.9
Patch foraging total patch changes 24 sec	0.1	0.2	0.5	0.4	-0.4	-0.4	0.5	0.6	0.5	0.4	0.4	-0.7	-0.3	0.2
Patch foraging total patch changes 6 sec	2.2	3.4	5.5	-0.2	-2.0	-2.0	1.9	2.0	1.8	1.8	1.8	-2.3	-1.9	1.7
Patch foraging time to switch 0 sec	0.1	0.2	0.5	-0.7	-0.7	-0.7	0.7	0.4	0.4	0.5	0.5	-0.3	0.1	-0.0
Patch foraging water rate 0 sec	0.1	0.2	0.5	0.1	-0.2	-0.2	0.2	0.4	0.4	0.4	0.4	-0.7	-0.7	0.5
Patch foraging water rate 12 sec	0.3	0.6	0.9	1.0	0.9	0.9	-1.0	-0.9	-0.8	-0.7	-0.7	0.3	0.7	-0.6
Patch foraging water rate 18 sec	0.1	0.2	0.7	0.8	-0.1	-0.1	0.1	0.2	0.2	0.2	0.2	-0.8	-0.4	0.1
Patch foraging water rate 24 sec	0.0	0.0	0.1	-0.3	0.0	0.0	-0.1	-0.1	-0.1	-0.0	-0.0	-0.0	-0.1	0.2
Patch foraging water rate 6 sec	1.9	2.7	4.0	2.0	1.8	1.8	-1.9	-1.7	-1.6	-1.6	-1.6	1.1	1.4	-1.3
Seeking ratio, delayed vs. immediate footshock	0.2	0.2	1.0	1.0	0.5	0.5	-0.4	-0.4	-0.4	-0.4	-0.4	-0.3	0.0	0.4
Distance traveled before self-admin	0.2	0.2	0.5	-0.1	-0.7	-0.7	0.5	0.3	0.3	0.3	0.3	-0.5	-0.2	0.6
Distance traveled after self-admin	2.6	3.2	4.5	-0.6	-2.0	-2.0	2.0	1.8	1.7	1.6	1.6	-2.1	-1.8	2.1
Extensor digitorum longus weight	0.1	0.4	0.7	0.6	0.7	0.7	-0.6	-0.7	-0.7	-0.6	-0.6	0.3	0.8	-0.5
Bone: elastic displacement	0.0	0.0	0.1	-0.0	0.1	0.1	-0.1	-0.1	-0.1	-0.2	-0.2	0.2	-0.0	-0.1
Bone: elastic work	2.4	3.1	5.6	-2.4	-1.8	-1.8	1.8	1.8	1.8	1.8	1.8	-1.2	-1.5	1.5
Bone: endosteal estimation	0.9	2.0	2.7	-1.6	-1.4	-1.4	1.5	1.6	1.6	1.7	1.7	-1.2	-1.0	0.6
Bone: endosteal perimeter	0.6	1.2	3.3	-1.8	-1.1	-1.1	1.1	1.1	1.2	1.2	1.2	-0.6	-0.7	0.5
Epididymis fat weight	0.4	1.3	8.6	-2.9	-0.7	-0.7	0.8	0.7	0.8	0.8	0.8	0.6	-0.4	1.1
Delta time in closed arm before/after self-admin	0.3	0.3	1.4	-0.5	-0.1	-0.1	0.4	0.5	0.5	0.5	0.5	-0.3	-0.7	1.2
Delta time in open arm before/after self-admin	0.2	0.2	1.7	0.5	-0.2	-0.2	-0.1	-0.1	-0.2	-0.2	-0.2	0.0	0.5	-1.3
Diff in mean of infusions in LGA sessions	0.8	0.9	1.7	-0.8	-0.9	-0.9	0.8	1.1	1.1	1.0	1.0	-0.8	-1.3	0.8
Delay discount exponential model param	0.6	0.7	1.2	-0.4	1.1	1.1	-0.8	-1.0	-0.8	-0.7	-0.7	1.1	0.9	0.4
Extinction: sum of active levers before priming	2.3	2.5	3.2	-1.6	-1.6	-1.6	1.6	1.8	1.8	1.8	1.8	-1.4	-1.5	0.9
Active lever presses in extinction session 6	0.4	0.4	0.7	-0.8	-0.6	-0.6	0.5	0.6	0.7	0.7	0.7	-0.5	-0.5	0.6
Bone: final force	3.5	5.6	6.5	-2.5	-2.4	-2.4	2.5	2.5	2.5	2.5	2.5	-2.0	-2.4	1.6
Bone: final moment	3.9	6.3	7.1	-2.5	-2.6	-2.6	2.6	2.6	2.7	2.7	2.7	-2.1	-2.6	1.8
Food consumed during 24 hour testing period	2.3	3.2	4.1	-2.0	-1.8	-1.8	1.8	1.8	1.8	1.8	1.8	-1.3	-1.8	1.8
Glucose	0.1	0.1	0.2	-0.4	-0.3	-0.3	0.3	0.1	0.2	0.3	0.3	-0.3	-0.1	0.5
Heart weight	3.3	5.0	10.4	-3.2	-2.2	-2.2	2.2	2.1	2.2	2.2	2.2	-1.4	-1.8	2.4
Delay discount hyperbolic model param	0.6	0.7	1.2	-0.4	1.1	1.1	-0.8	-0.9	-0.8	-0.7	-0.7	1.0	0.8	0.3
Intermittent access intake day 1-15 change	0.4	0.7	0.9	0.7	1.0	1.0	-1.0	-0.9	-0.9	-0.8	-0.8	0.6	0.9	-0.8
Intermittent access intake escalation	0.5	1.0	1.3	1.0	1.2	1.2	-1.1	-1.1	-1.0	-1.0	-1.0	0.7	0.9	-0.8
Intermittent access intake escalation 2	0.7	0.8	1.3	0.7	1.1	1.1	-1.0	-0.9	-0.8	-0.8	-0.8	0.6	1.0	-1.0
Intermitt. access day 1 inactive lever presses	0.4	1.7	2.1	-1.3	-1.4	-1.4	1.3	1.2	1.2	1.3	1.3	-1.2	-1.1	1.4
Intermitt. access day 15 inactive lever presses	0.3	0.6	1.3	-0.2	-0.6	-0.6	0.7	0.7	0.8	0.8	0.8	-1.2	-0.8	0.9
Intermitt. access escalation Index	0.2	0.3	0.7	0.8	0.5	0.5	-0.6	-0.7	-0.6	-0.6	-0.6	0.3	0.3	0.3
Intermittent access day 1 total infusions	1.8	2.9	3.7	-1.3	-1.9	-1.9	1.9	1.9	1.8	1.8	1.8	-1.6	-1.7	0.9
Intermittent access day 15 total infusions	0.1	0.1	0.2	0.4	-0.2	-0.2	0.2	0.3	0.2	0.2	0.2	-0.5	-0.1	-0.5
Intermittent access terminal intake (last 3 days)	0.0	0.1	0.5	0.2	-0.1	-0.1	0.1	0.2	0.2	0.2	0.2	-0.2	0.1	-0.7
Intermittent access total infusions	1.7	2.0	2.6	-0.9	-1.6	-1.6	1.6	1.6	1.6	1.5	1.5	-1.5	-1.2	0.3
Intermittent access day 1 locomotion	1.8	2.3	3.2	-1.1	-1.8	-1.8	1.8	1.6	1.6	1.6	1.6	-1.6	-1.3	0.9
Intermittent access day 15 total locomotion	1.0	1.8	2.3	-1.2	-1.4	-1.4	1.5	1.5	1.5	1.5	1.5	-1.4	-1.2	0.2
Intermittent access total locomotion	2.6	3.1	4.0	-1.5	-1.9	-1.9	2.0	2.0	1.9	1.9	1.9	-1.8	-1.5	0.5
Intermittent access standard deviation	0.6	1.3	2.4	-1.6	-1.3	-1.3	1.2	1.1	1.2	1.3	1.3	-0.9	-0.5	0.5
Left kidney weight	2.3	10.8	39.4	-6.3	-2.8	-2.8	3.0	2.9	3.1	3.1	3.1	-0.7	-2.9	3.0
Right kidney weight	3.4	15.3	52.1	-7.2	-3.5	-3.5	3.5	3.4	3.6	3.6	3.6	-1.0	-3.4	4.0
Cocaine induced anxiety	1.0	1.5	3.7	-1.9	-1.0	-1.0	1.2	1.2	1.2	1.2	1.2	-0.5	-1.2	1.1
Post-drug Anxiety	0.1	0.1	0.2	-0.2	0.4	0.4	-0.2	-0.2	-0.2	-0.2	-0.2	0.4	0.0	0.0
Baseline Anxiety	1.8	2.1	5.3	2.3	1.3	1.3	-1.4	-1.4	-1.4	-1.5	-1.5	0.7	1.2	-1.4
Tail length	0.2	0.6	1.6	1.2	0.6	0.6	-0.7	-0.9	-0.9	-0.9	-0.9	0.6	0.8	-0.1
Length with tail	0.0	0.1	0.6	-0.8	-0.1	-0.1	0.1	0.1	0.1	0.1	0.1	0.4	-0.3	0.7
Length without tail	0.9	3.0	8.5	-2.9	-1.6	-1.6	1.6	1.7	1.8	1.7	1.7	-0.6	-1.6	1.5
Times rat made contact with spout	0.5	0.6	1.1	-0.5	-0.7	-0.7	0.7	0.8	0.8	0.8	0.7	-0.6	-1.0	0.8
Lifetime Intake	3.5	4.3	5.3	-1.6	-2.3	-2.3	2.3	2.3	2.2	2.2	2.2	-2.0	-2.0	1.3
Liver weight, left	1.1	1.8	3.6	0.0	1.3	1.3	-1.3	-1.2	-1.2	-1.3	-1.3	1.9	1.3	-1.8
Liver weight, right	2.8	4.9	10.0	-0.4	2.2	2.2	-2.1	-2.3	-2.2	-2.2	-2.2	3.2	2.2	-2.3
Locomotor activity	0.3	0.4	2.1	-1.5	-0.6	-0.6	0.5	0.5	0.5	0.6	0.6	0.1	-0.3	0.4
Locomotor testing distance	0.0	0.0	0.1	0.3	0.1	0.1	-0.2	-0.2	-0.2	-0.2	-0.2	0.1	0.2	-0.3
Locomotor testing rearing	0.1	0.1	1.2	-1.1	-0.2	-0.2	0.1	0.1	0.2	0.2	0.2	0.3	-0.0	0.1
Locomotion in novel chamber	3.4	4.3	5.1	2.2	2.1	2.1	-2.1	-2.2	-2.2	-2.2	-2.2	1.7	2.3	-1.3
Locomotion in novel chamber post-restriction	0.6	1.0	2.1	1.1	0.9	0.9	-1.0	-1.0	-0.9	-0.8	-0.8	0.6	1.1	-1.4
Fecal boli incidents, locomotor time 1	1.3	1.9	2.8	-0.3	-1.6	-1.6	1.3	1.5	1.4	1.4	1.4	-1.7	-1.3	1.0
Change in fecal boli incidents, locomotor task	0.6	0.6	1.4	0.4	0.8	0.8	-0.7	-0.7	-0.8	-0.9	-0.9	1.2	0.3	-0.1
Time >=10cm from walls, locomotor time 1	0.8	0.8	1.2	-1.1	-0.9	-0.9	0.8	0.9	0.9	0.9	0.9	-0.6	-0.8	0.9
Bouts of movement, locomotor time 1	0.2	0.3	1.0	-1.0	-0.3	-0.3	0.5	0.6	0.6	0.5	0.5	0.1	-0.5	-0.0
Total resting periods, locomotor time 1	0.5	0.5	1.1	-1.0	-0.5	-0.5	0.8	0.8	0.8	0.8	0.8	-0.3	-0.8	0.3
Rest time, locomotor task time 1	0.9	1.1	1.6	-1.3	-1.0	-1.0	1.2	1.1	1.1	1.1	1.1	-0.7	-1.1	0.9
Distance moved, locomotor task time 1	0.5	0.7	1.3	0.2	0.7	0.7	-1.0	-1.0	-1.0	-0.9	-0.9	1.2	1.1	-0.2
Vertical activity count, locomotor time 1	0.0	0.0	0.1	0.0	-0.1	-0.1	-0.2	-0.1	-0.1	-0.0	-0.0	-0.0	0.2	0.3
Time >=10cm from walls, locomotor time 2	0.1	0.2	0.3	-0.1	-0.4	-0.4	0.4	0.3	0.3	0.3	0.3	-0.5	-0.4	0.6
Bouts of movement, locomotor time 2	0.0	0.1	0.4	-0.4	0.0	0.0	-0.1	-0.2	-0.2	-0.1	-0.1	0.4	0.0	0.6
Total resting periods, locomotor time 2	0.1	0.1	0.5	-0.5	-0.4	-0.4	0.3	0.3	0.3	0.3	0.3	-0.1	-0.4	0.7
Rest time, locomotor task time 2	0.1	0.2	0.4	0.1	-0.4	-0.4	0.3	0.5	0.4	0.4	0.4	-0.5	-0.6	0.3
Distance moved, locomotor task time 2	0.3	0.4	1.1	-0.2	0.5	0.5	-0.5	-0.7	-0.7	-0.7	-0.7	1.1	0.8	-0.2
Vertical activity count, locomotor time 2	0.2	0.2	0.6	-0.6	-0.8	-0.8	0.3	0.4	0.3	0.3	0.3	-0.1	-0.2	0.7
Light reinforcement 1	0.0	0.1	0.2	0.1	-0.2	-0.2	0.2	0.3	0.2	0.2	0.2	-0.4	-0.2	0.2
Light reinforcement 2	0.5	0.8	1.7	-0.4	0.9	0.9	-0.9	-1.0	-0.9	-0.9	-0.9	1.3	0.9	-0.3
Bone: marrow area	1.1	2.3	3.1	-1.6	-1.5	-1.5	1.6	1.7	1.7	1.8	1.8	-1.3	-1.1	0.7
Bone: maximum diameter	3.3	6.2	10.1	-3.2	-2.4	-2.4	2.5	2.5	2.6	2.6	2.6	-1.8	-2.4	2.1
Bone: maximum force	5.2	9.2	10.6	-3.0	-3.1	-3.1	3.1	3.2	3.2	3.3	3.3	-2.6	-3.0	2.4
Bone: maximum moment	5.6	9.8	11.1	-3.1	-3.2	-3.2	3.2	3.3	3.3	3.3	3.3	-2.6	-3.1	2.6
Mean time between licks in bursts	0.2	0.5	0.7	0.8	0.7	0.7	-0.7	-0.8	-0.8	-0.7	-0.7	0.4	0.8	0.0
Mean num. licks in bursts	0.2	0.3	2.0	-1.4	-0.4	-0.4	0.4	0.5	0.5	0.5	0.5	0.2	-0.5	0.1
Cd content in liver	0.1	0.1	0.4	-0.3	-0.1	-0.1	0.2	0.3	0.2	0.1	0.1	0.1	-0.6	0.0
Co content in liver	1.1	1.3	2.8	-0.4	-1.1	-1.1	1.1	1.0	1.0	1.0	1.0	-1.2	-1.4	1.7
Cu content in liver	0.4	0.5	4.1	2.0	0.2	0.2	-0.1	-0.2	-0.2	-0.2	-0.2	-1.0	0.1	-0.6
Fe content in liver	2.2	2.7	3.2	-1.8	-1.8	-1.8	1.7	1.6	1.6	1.7	1.7	-1.5	-1.3	1.6
K content in liver	0.5	0.5	1.4	1.2	0.7	0.7	-0.7	-0.7	-0.7	-0.6	-0.6	0.2	0.4	-0.1
Mg content in liver	0.1	0.1	0.4	0.6	0.2	0.2	-0.0	0.1	0.1	0.1	0.1	-0.5	-0.3	0.0
Mn content in liver	0.8	0.9	1.3	0.7	1.2	1.2	-1.0	-0.9	-0.9	-0.9	-0.9	1.0	0.7	-0.6
Na content in liver	0.1	0.2	1.0	1.0	0.1	0.1	-0.2	-0.3	-0.3	-0.3	-0.3	-0.3	0.4	-0.2
Rb content in liver	1.9	2.2	2.8	-0.8	-1.5	-1.5	1.5	1.6	1.6	1.5	1.5	-1.5	-1.7	1.6
Se content in liver	1.3	1.6	1.8	1.2	1.3	1.3	-1.3	-1.3	-1.3	-1.3	-1.3	1.1	1.1	-1.1
Sr content in liver	1.9	1.7	3.0	1.7	1.3	1.3	-1.3	-1.4	-1.4	-1.3	-1.3	0.8	1.2	-0.9
Zn content in liver	0.1	0.1	0.7	0.5	0.2	0.2	-0.2	-0.2	-0.2	-0.2	-0.2	0.1	0.0	-0.8
Bone: minimum diameter	0.9	1.7	2.4	-1.3	-1.3	-1.3	1.4	1.4	1.5	1.5	1.5	-1.2	-1.0	0.5
Time in familiar zone, hab. session 1	0.8	0.8	1.3	-0.3	-0.9	-0.9	0.9	1.0	1.0	0.9	0.9	-0.9	-1.2	0.7
Time in novel zone, hab. session 1	0.4	0.4	1.0	-0.5	0.6	0.6	-0.5	-0.7	-0.6	-0.5	-0.5	0.8	1.0	-0.2
Total zone transitions, hab. session 1	2.4	3.3	9.3	3.1	1.8	1.8	-1.8	-1.6	-1.7	-1.8	-1.8	1.0	1.2	-1.9
Total locomotion distance, hab. session 1	2.6	3.6	7.2	2.7	1.9	1.9	-1.9	-1.7	-1.8	-1.9	-1.9	1.4	1.7	-1.9
Locomotion velocity, hab. session 1	1.6	2.3	6.5	2.5	1.4	1.4	-1.5	-1.3	-1.4	-1.4	-1.5	0.8	1.3	-1.5
Time in familiar zone, hab. session 2	1.9	2.0	2.9	0.8	1.4	1.4	-1.4	-1.4	-1.4	-1.4	-1.4	1.6	1.6	-1.7
Time in novel zone, hab. session 2	1.6	1.6	2.2	-0.8	-1.2	-1.2	1.3	1.3	1.3	1.3	1.3	-1.3	-1.3	1.5
Total zone transitions, hab. session 2	0.7	0.9	2.2	0.8	-0.9	-0.9	0.9	1.0	0.9	0.9	0.9	-1.5	-1.3	0.6
Total locomotion distance, hab. session 2	0.4	0.5	1.5	0.8	-0.6	-0.6	0.6	0.7	0.6	0.6	0.6	-1.2	-0.7	0.7
Locomotion velocity, hab. session 2	0.5	0.6	1.9	1.0	-0.6	-0.6	0.6	0.7	0.7	0.6	0.6	-1.4	-0.7	0.7
Novel to familiar place preference ratio	0.2	0.2	1.1	-1.0	0.2	0.2	-0.1	-0.1	-0.1	-0.1	-0.1	0.8	0.2	0.1
Novelty place preference	0.3	0.3	1.3	-1.1	0.4	0.4	-0.3	-0.3	-0.3	-0.3	-0.3	1.1	0.3	0.0
Time in novel zone, NPP test	0.3	0.3	1.7	-1.3	0.3	0.3	-0.2	-0.3	-0.2	-0.2	-0.2	1.1	0.2	0.1
Total zone transitions, NPP test	1.1	1.6	7.5	2.7	1.1	1.1	-1.1	-0.9	-1.0	-1.1	-1.1	0.3	0.6	-1.5
Total locomotion distance, NPP test	0.3	0.4	2.8	1.7	0.4	0.4	-0.4	-0.3	-0.3	-0.4	-0.4	-0.2	0.1	-0.4
Locomotion velocity, NPP test	0.5	0.7	4.1	2.0	0.6	0.6	-0.7	-0.6	-0.6	-0.7	-0.7	-0.0	0.5	-0.6
Intraocular pressure	0.0	0.0	0.2	-0.3	0.0	0.0	-0.1	0.0	0.0	-0.0	-0.0	0.4	-0.0	0.0
Delta distance traveled before/after self-admin	1.3	1.4	2.2	-0.8	-1.1	-1.1	1.4	1.3	1.2	1.2	1.2	-1.1	-1.5	1.1
Delta ambulatory time before/after self-admin	1.6	1.9	3.0	-0.9	-1.3	-1.3	1.6	1.5	1.4	1.3	1.3	-1.4	-1.7	1.3
Parametrial fat weight	0.7	1.6	2.4	0.6	1.2	1.2	-1.3	-1.3	-1.3	-1.3	-1.3	1.5	1.5	-1.1
Pavlov. Cond. lever latency	0.0	0.0	0.3	-0.6	-0.0	-0.0	0.2	0.2	0.2	0.2	0.2	0.2	-0.1	-0.1
Pavlov. Cond. magazine entry latency	0.2	0.2	0.5	0.4	-0.4	-0.4	0.3	0.4	0.3	0.3	0.3	-0.7	-0.5	0.6
Pavlov. Cond. change in total contacts	1.2	1.2	2.7	0.4	-1.0	-1.0	1.0	1.1	1.0	1.0	1.0	-1.6	-1.3	1.3
Pavlov. Cond. index score	0.3	0.3	0.6	0.1	-0.6	-0.6	0.5	0.6	0.5	0.5	0.5	-0.8	-0.7	0.8
Pavlov. Cond. latency score	0.1	0.2	0.4	0.2	-0.4	-0.4	0.3	0.3	0.3	0.3	0.3	-0.6	-0.4	0.6
Pavlov. Cond. lever contacts	0.1	0.1	0.8	0.9	-0.0	-0.0	-0.1	-0.1	-0.1	-0.1	-0.1	-0.5	0.1	-0.1
Pavlov. Cond. magazine entry number	0.2	0.2	0.5	-0.5	0.3	0.3	-0.3	-0.3	-0.3	-0.3	-0.3	0.6	0.5	-0.7
Pavlov. Cond. intertrial magazine entries	0.4	0.4	1.2	0.6	-0.6	-0.6	0.6	0.7	0.6	0.6	0.6	-1.1	-0.6	0.3
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.4	0.3	-0.4	-0.4	0.3	0.4	0.3	0.3	0.3	-0.6	-0.5	0.5
Pavlov. Cond. response bias	0.2	0.2	0.5	0.5	-0.4	-0.4	0.3	0.4	0.3	0.3	0.3	-0.7	-0.5	0.5
Pavlov. Cond. lever latency	0.1	0.1	0.8	-0.4	0.3	0.3	-0.3	-0.2	-0.2	-0.3	-0.3	0.9	0.2	-0.2
Pavlov. Cond. magazine entry latency	1.1	1.3	3.6	0.5	-1.1	-1.1	1.1	1.1	1.1	1.1	1.1	-1.9	-1.2	0.9
Pavlov. Cond. change in total contacts	2.6	4.2	7.2	-0.9	-2.1	-2.1	2.1	2.0	2.1	2.2	2.2	-2.7	-2.2	1.7
Pavlov. Cond. index score	0.5	0.6	2.1	0.4	-0.7	-0.7	0.7	0.7	0.7	0.8	0.8	-1.5	-0.8	0.5
Pavlov. Cond. latency score	0.5	0.7	2.4	0.6	-0.7	-0.7	0.7	0.7	0.7	0.8	0.8	-1.6	-0.8	0.5
Pavlov. Cond. lever contacts	0.1	0.1	0.7	0.5	-0.2	-0.2	0.2	0.1	0.1	0.2	0.2	-0.8	-0.2	0.1
Pavlov. Cond. magazine entry number	0.5	0.7	2.0	-0.4	0.7	0.7	-0.7	-0.7	-0.8	-0.8	-0.8	1.4	0.9	-0.6
Pavlov. Cond. intertrial magazine entries	0.5	0.7	1.9	-1.4	-0.9	-0.9	0.9	0.9	0.8	0.7	0.7	-0.2	-0.9	1.0
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.6	2.0	0.5	-0.7	-0.7	0.7	0.6	0.7	0.8	0.8	-1.4	-0.7	0.5
Pavlov. Cond. response bias	0.6	0.8	2.3	0.1	-0.9	-0.9	0.9	0.8	0.8	0.9	0.9	-1.5	-0.9	0.8
Time in closed arm before self-admin	0.4	0.5	1.5	0.9	-0.9	-0.9	0.7	0.4	0.3	0.4	0.4	-1.2	-0.0	-0.5
Time in closed arm after self-admin	0.5	0.5	0.8	-0.6	-0.8	-0.8	0.9	0.8	0.8	0.8	0.8	-0.6	-0.5	0.4
Time in open arm before self-admin	1.5	1.6	2.7	0.7	1.6	1.6	-1.4	-1.3	-1.3	-1.3	-1.3	1.4	1.1	-0.6
Time in open arm after self-admin	1.2	1.3	2.3	1.1	1.0	1.0	-1.1	-1.1	-1.1	-1.2	-1.2	1.0	1.3	-1.5
Bone: periosteal estimation	1.8	3.9	5.0	-2.2	-2.0	-2.0	2.1	2.1	2.2	2.2	2.2	-1.6	-1.7	1.2
Bone: periosteal perimeter	1.6	2.7	7.0	-2.6	-1.5	-1.5	1.7	1.7	1.7	1.8	1.8	-0.9	-1.3	1.0
Bone: post-yield work	2.8	4.1	4.8	-1.2	-2.0	-2.0	2.0	2.2	2.2	2.1	2.1	-2.0	-2.2	2.1
Progressive ratio test 1 active lever presses	2.1	2.6	3.3	-1.0	-1.8	-1.8	1.8	1.8	1.7	1.7	1.6	-1.6	-1.6	0.9
Progressive ratio test 1 breakpoint	1.6	2.0	2.6	-0.8	-1.6	-1.6	1.6	1.6	1.5	1.4	1.4	-1.4	-1.4	0.8
Progressive ratio test 1 inactive lever presses	2.3	3.3	4.2	-1.2	-2.0	-2.0	2.0	1.9	1.9	1.9	1.9	-2.0	-1.5	1.1
Progressive ratio test 2 active lever presses	1.8	2.1	2.9	-0.7	-1.5	-1.5	1.5	1.7	1.6	1.5	1.5	-1.6	-1.6	0.6
Progressive ratio test 2 breakpoint	1.6	1.8	2.6	-0.6	-1.4	-1.4	1.4	1.6	1.5	1.4	1.4	-1.5	-1.5	0.5
Progressive ratio test 2 inactive lever presses	0.2	0.3	0.8	0.4	-0.6	-0.6	0.5	0.6	0.6	0.6	0.6	-0.9	-0.3	-0.5
Incentive Sensitization - Responses	0.0	0.0	0.3	0.5	0.2	0.2	-0.2	-0.0	-0.0	-0.1	-0.1	-0.2	-0.1	-0.3
Incentive Sensitization - Breakpoint	0.0	0.0	0.1	0.3	0.0	0.0	-0.1	0.1	0.1	0.0	0.0	-0.3	-0.3	-0.1
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	-0.2	0.1	0.1	-0.0	0.0	0.0	0.1	0.1	-0.1	0.1	-0.3
Progressive ratio	0.1	0.2	0.3	-0.3	-0.5	-0.5	0.5	0.5	0.5	0.5	0.5	-0.6	-0.2	-0.2
Food seeking constrained by brief footshock	0.9	1.2	2.1	-1.1	-1.0	-1.0	1.1	1.0	1.1	1.1	1.1	-0.7	-1.0	1.5
Seeking ratio, punishment vs. effort	0.3	0.5	1.7	-0.6	-0.6	-0.6	0.6	0.6	0.6	0.6	0.6	-0.4	-0.7	1.3
Retroperitoneal fat weight	0.6	2.4	14.7	-3.8	-1.0	-1.0	1.0	0.9	1.0	1.0	1.0	0.9	-0.8	1.8
Reaction time number correct	1.7	3.2	5.2	1.8	1.8	1.8	-1.9	-1.7	-1.7	-1.8	-1.8	1.5	1.5	-2.3
Reaction time mean minus median	0.1	0.1	1.0	-0.2	0.1	0.1	-0.2	-0.2	-0.2	-0.1	-0.1	0.3	0.6	-1.0
Reaction time mean minus median AUC	0.1	0.4	1.3	-0.6	0.3	0.3	-0.4	-0.5	-0.4	-0.4	-0.4	0.8	0.8	-1.1
Reaction time num false alarms	0.2	0.2	0.4	0.3	0.5	0.5	-0.5	-0.5	-0.5	-0.4	-0.4	0.4	0.6	-0.5
Reaction time num false alarms AUC	0.4	0.6	0.8	0.7	0.8	0.8	-0.8	-0.8	-0.8	-0.7	-0.7	0.6	0.9	-0.7
Reaction time trials correct on left	1.7	3.2	5.2	1.8	1.8	1.8	-1.9	-1.7	-1.7	-1.8	-1.8	1.5	1.5	-2.3
Reaction time trials on left	1.8	3.4	5.6	1.9	1.8	1.8	-1.9	-1.8	-1.8	-1.8	-1.8	1.5	1.5	-2.4
Reaction time mean	0.1	0.1	0.3	0.1	0.3	0.3	-0.4	-0.4	-0.3	-0.3	-0.2	0.1	0.6	-0.1
Reaction time mean AUC	0.1	0.1	0.3	0.2	0.3	0.3	-0.3	-0.4	-0.3	-0.3	-0.3	0.2	0.5	-0.1
Median of all reaction times	0.1	0.1	0.2	0.2	0.3	0.3	-0.4	-0.5	-0.3	-0.3	-0.3	0.1	0.5	0.2
Reaction time omissions	0.4	0.6	1.8	0.9	0.7	0.7	-0.7	-0.7	-0.7	-0.7	-0.7	0.5	0.8	-1.3
Reaction time false alarm rate	0.0	0.0	0.1	-0.3	0.0	0.0	0.0	-0.1	0.0	0.1	0.1	-0.0	0.2	0.4
Reaction time premature initiation rate	2.1	2.9	5.5	-0.8	-1.5	-1.5	1.6	1.6	1.6	1.7	1.7	-2.1	-1.7	2.4
Reaction time premature initiations	0.4	0.6	1.3	-0.1	-0.6	-0.6	0.6	0.7	0.8	0.8	0.8	-1.1	-0.9	1.2
Std. dev. reaction times	0.1	0.2	0.5	-0.3	0.2	0.2	-0.3	-0.4	-0.3	-0.2	-0.2	0.5	0.7	-0.7
Reaction time trials completed	1.8	3.4	5.6	1.9	1.8	1.8	-1.9	-1.8	-1.8	-1.8	-1.8	1.5	1.5	-2.4
Reaction time trials AUC	1.3	2.5	4.3	1.6	1.6	1.6	-1.7	-1.5	-1.6	-1.6	-1.6	1.4	1.3	-2.1
Run reversals in cocaine runway, females	0.6	0.6	0.9	0.9	0.9	0.9	-0.8	-0.8	-0.8	-0.8	-0.8	0.6	0.7	-0.8
Run reversals in cocaine runway, males	0.1	0.1	0.3	-0.3	-0.1	-0.1	0.1	0.2	0.1	-0.0	-0.0	0.5	-0.1	-0.3
Latency to leave start box in cocaine runway	0.3	0.3	0.8	-0.5	0.5	0.5	-0.4	-0.5	-0.6	-0.6	-0.6	0.9	0.5	-0.4
Latency to leave start box in cocaine runway, F	0.1	0.1	0.1	0.1	0.4	0.4	-0.3	-0.3	-0.3	-0.2	-0.2	0.3	0.2	-0.2
Latency to leave start box in cocaine runway, M	0.5	0.4	1.4	-0.7	0.5	0.5	-0.4	-0.6	-0.7	-0.7	-0.7	1.2	0.6	-0.4
Std. dev. time between licks in bursts	0.5	0.7	1.7	0.6	-0.7	-0.7	0.7	0.7	0.6	0.6	0.6	-1.3	-0.8	1.3
Total sessions with >9 infusions	5.5	6.7	9.1	-2.8	-2.7	-2.7	2.6	2.5	2.5	2.5	2.5	-1.9	-2.7	3.0
Short access day 1 total inactive lever presses	7.7	10.1	12.1	-2.0	-3.5	-3.5	3.4	3.3	3.3	3.3	3.3	-3.5	-3.1	2.5
Short access day 10 total inactive lever presses	0.1	0.2	0.5	-0.7	-0.4	-0.4	0.5	0.5	0.6	0.6	0.6	-0.3	-0.2	-0.2
Short access day 1 total infusions	2.7	3.6	4.7	-1.6	-2.2	-2.2	2.0	1.8	1.8	1.8	1.8	-1.7	-1.8	2.0
Short access day 10 total infusions	3.0	3.9	5.2	-2.1	-2.3	-2.3	2.1	1.9	1.9	1.9	1.9	-1.6	-1.8	1.7
Short access total infusions	6.4	8.2	9.7	-2.6	-3.1	-3.1	3.0	2.9	2.8	2.8	2.8	-2.5	-2.9	2.8
Short access day 1 locomotion	0.9	1.1	1.8	-1.1	-1.3	-1.3	1.1	0.9	0.9	0.9	0.9	-0.9	-0.8	1.3
Short access day 10 total locomotion	0.2	0.4	1.0	-0.5	-1.0	-1.0	0.8	0.5	0.5	0.6	0.6	-0.7	-0.1	0.3
Short access total locomotion	1.9	2.3	3.2	-1.7	-1.8	-1.8	1.7	1.3	1.3	1.4	1.4	-1.2	-1.2	1.8
One hour access (0.3 mA shock)	0.2	0.2	0.8	0.1	-0.4	-0.4	0.4	0.5	0.5	0.5	0.5	-0.7	-0.0	-0.9
Compulsive drug intake	0.2	0.2	1.2	1.1	0.5	0.5	-0.4	0.0	-0.1	-0.2	-0.2	-0.2	-0.5	0.0
One hour access (shock baseline)	0.2	0.2	0.5	-0.5	-0.6	-0.6	0.5	0.3	0.4	0.5	0.5	-0.3	0.2	-0.7
Social response proportion	0.4	0.4	2.4	-0.9	-0.5	-0.5	0.4	0.2	0.3	0.4	0.4	-0.4	-0.2	1.6
Social responses	0.1	0.1	0.3	0.3	-0.2	-0.2	0.1	0.2	0.2	0.2	0.2	-0.4	-0.2	0.5
Social time	0.1	0.2	1.6	1.3	0.1	0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.6	0.2	-0.2
Soleus weight	0.1	0.4	0.9	0.5	-0.5	-0.5	0.5	0.6	0.6	0.5	0.5	-0.9	-1.0	0.8
Bone: stiffness	3.7	6.1	7.0	-2.5	-2.5	-2.5	2.5	2.5	2.6	2.6	2.6	-2.2	-2.3	2.1
Tibialis anterior weight	0.0	0.1	0.9	1.0	-0.1	-0.1	0.1	0.2	0.1	0.1	0.1	-0.8	-0.1	-0.2
Time to tail flick, vehicle, before self-admin	0.3	0.4	0.5	-0.4	-0.7	-0.7	0.7	0.7	0.6	0.6	0.6	-0.7	-0.5	0.0
Time to tail flick, vehicle, after self-admin	0.3	0.4	2.1	0.9	0.4	0.4	-0.4	-0.3	-0.3	-0.3	-0.3	0.1	0.5	-1.5
Time to tail flick, test, before self-admin	0.3	0.3	0.9	-0.0	0.5	0.5	-0.4	-0.5	-0.5	-0.6	-0.6	0.9	0.6	-0.7
Time to tail flick, test, after self-admin	0.4	0.4	0.6	0.8	0.7	0.7	-0.6	-0.6	-0.6	-0.6	-0.6	0.4	0.7	-0.2
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.2	-0.2	-0.3	-0.3	0.3	0.4	0.4	0.4	0.4	-0.4	-0.1	-0.1
Delta time to tail flick, test, before/after SA	0.5	0.6	2.2	1.5	0.8	0.8	-0.7	-0.7	-0.7	-0.7	-0.6	-0.1	0.6	-0.0
Tibia length	0.7	2.0	2.9	-1.5	-1.4	-1.4	1.4	1.6	1.5	1.4	1.4	-1.0	-1.7	1.1
Ambulatory time before self-admin	0.0	0.1	0.3	0.6	-0.0	-0.0	-0.2	-0.2	-0.2	-0.2	-0.2	-0.1	0.3	0.2
Ambulatory time after self-admin	0.8	0.9	2.1	0.6	-1.0	-1.0	1.0	0.9	0.7	0.7	0.7	-1.4	-1.1	1.1
Bone: tissue strength	0.0	0.0	0.1	-0.3	-0.1	-0.1	0.1	0.1	0.1	0.1	0.1	0.1	-0.2	0.0
Total heroin consumption	1.0	1.2	1.7	-0.8	-1.1	-1.1	1.1	1.2	1.2	1.1	1.1	-1.1	-1.3	1.0
Bone: trabecular number	0.2	0.4	0.9	0.3	0.7	0.7	-0.6	-0.6	-0.5	-0.6	-0.6	0.6	0.5	-0.9
Bone: trabecular spacing	3.0	4.0	4.6	-1.8	-2.0	-2.0	2.0	2.1	2.1	2.1	2.1	-1.6	-2.0	2.1
Bone: trabecular thickness	0.5	0.6	1.1	0.4	0.8	0.8	-0.7	-0.9	-0.8	-0.7	-0.7	0.5	1.0	-1.0
Bone: trabecular tissue density	0.1	0.1	0.8	0.9	0.2	0.2	-0.2	-0.3	-0.2	-0.1	-0.1	-0.6	0.3	0.0
Water consumed over 24 hours	0.8	1.1	1.4	-0.8	-1.1	-1.1	1.1	1.1	1.1	1.0	1.0	-0.9	-1.2	1.1
Number of responses in last shaping day	3.3	3.6	5.6	-1.0	-2.2	-2.2	2.0	1.9	1.9	2.0	2.0	-2.4	-1.7	1.3