Hub : Genes

Sgsh

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Sgsh 0.15 0.08 1.1e-09 0.1 0.1 0.08 0.1 7.8e-10 1.9e-09 6.0e-08 8.5e-10
2 BLA gene expression Sgsh 0.06 0.05 3.7e-03 0.05 0.02 0.05 0 1.8e-03 2.5e-02 9.4e-04 3.3e-01
3 PL gene expression Sgsh 0.11 0.06 2.3e-13 0.09 0.09 0.09 0.12 1.1e-09 1.9e-10 3.5e-10 5.2e-13
4 NAcc gene expression Sgsh 0.08 0.04 2.9e-09 0.05 0.06 0.06 0.06 6.2e-08 9.2e-09 1.1e-09 6.0e-09
5 LHb isoform ratio NM_001427070.1 0.2 0.12 3.7e-03 0.01 0.05 0.06 0.03 1.9e-01 3.0e-02 1.8e-02 6.2e-02
6 IC intron excision ratio chr10_105105485_105105770 0.09 0.06 6.1e-03 0.05 0.04 0.05 0.06 2.8e-03 1.1e-02 3.4e-03 2.4e-03
7 BLA intron excision ratio chr10_105105485_105105770 0.13 0.07 3.1e-06 0.11 0.11 0.1 0.1 2.8e-06 3.0e-06 7.3e-06 4.9e-06
8 Brain alternative TSS XM_039087539.2 0.04 0.03 9.4e-03 0.01 0.02 0.02 0.02 4.1e-02 6.6e-03 9.5e-03 4.9e-03
9 Brain intron excision ratio chr10_105104221_105105770 0.06 0.04 1.2e-05 0.05 0.05 0.04 0.05 1.3e-05 4.0e-05 5.8e-05 3.6e-05
10 PL intron excision ratio chr10_105104221_105105770 0.06 0.03 3.5e-07 0.05 0.04 0.05 0.04 2.6e-06 3.9e-05 6.1e-06 1.6e-05
11 IC intron excision ratio chr10_105104221_105105770 0.12 0.08 7.0e-04 0.09 0.08 0.06 0.08 1.4e-04 3.7e-04 1.4e-03 3.6e-04
12 pVTA intron excision ratio chr10_105105485_105105770 0.06 0.04 4.2e-04 0.03 0.02 0.01 0.02 1.9e-03 4.5e-03 2.1e-02 5.9e-03
13 BLA intron excision ratio chr10_105104221_105105770 0.23 0.14 5.6e-06 0.13 0.11 0.1 0.1 3.4e-07 1.8e-06 6.3e-06 3.9e-06
14 pVTA intron excision ratio chr10_105104221_105105770 0.08 0.05 4.6e-06 0.08 0.06 0.07 0.08 9.2e-07 1.1e-05 2.1e-06 4.6e-07
15 Brain intron excision ratio chr10_105105485_105105770 0.03 0.02 1.9e-03 0.04 0.01 0.02 0.01 3.2e-04 4.9e-02 9.8e-03 1.2e-02
16 Adipose alternative polyA NM_001427070.1 0.14 0.08 2.6e-14 0.13 0.12 0.11 0.12 8.2e-14 7.3e-13 3.5e-12 1.7e-13
17 Adipose alternative polyA XM_039087538.2 0.15 0.08 1.9e-14 0.13 0.12 0.11 0.12 7.5e-14 5.3e-13 1.9e-12 1.1e-13
18 Adipose alternative polyA NM_001427070.1 0.1 0.07 3.5e-08 0.07 0.05 0.05 0.06 5.4e-08 1.4e-06 5.0e-06 3.3e-07
19 Adipose alternative polyA XM_039087538.2 0.1 0.07 2.8e-08 0.07 0.05 0.05 0.06 4.8e-08 1.2e-06 3.5e-06 2.5e-07
20 Adipose isoform ratio NM_001427070.1 0.15 0.08 8.9e-15 0.12 0.11 0.11 0.12 4.2e-13 3.8e-12 1.2e-12 6.2e-13
21 Adipose mRNA stability Sgsh 0.06 0.04 5.4e-06 0.04 0.04 0.04 0.04 1.0e-05 2.4e-05 5.9e-05 2.6e-05
22 OFC gene expression Sgsh 0.27 0.13 5.2e-05 0.18 0.1 0.18 0.17 4.7e-05 2.8e-03 5.4e-05 8.3e-05
23 Liver gene expression Sgsh 0.12 0.06 4.4e-12 0.05 0.1 0.09 0.09 2.9e-06 4.8e-11 6.9e-10 1.2e-10
24 Adipose gene expression Sgsh 0.06 0.04 2.1e-06 0.07 0.06 0.06 0.06 7.5e-08 7.3e-07 4.7e-07 4.7e-07
25 Adipose isoform ratio XM_039087538.2 0.03 0.02 3.8e-03 0.01 0 -0 0 2.1e-02 2.0e-01 9.9e-01 2.9e-01
26 Adipose intron excision ratio chr10_105105485_105105770 0.04 0.03 2.2e-04 0.03 0.02 0.02 0.02 2.2e-04 3.4e-03 1.1e-03 9.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.10.22.6-0.1-0.1-0.20.3-1.60.60.30.3-0.3-0.3-0.20.2-0.4-0.10.1-0.10.1-0.10.1-0.10.1-0.10.70.50.10.1
Area under the delay curve0.80.95.21.01.11.00.92.3-1.3-1.2-0.60.50.60.8-0.80.50.8-0.80.8-0.80.8-0.80.8-0.80.8-1.00.7-0.7-0.7
BMI with tail0.93.13.9-1.6-1.7-1.8-0.3-0.81.81.92.0-1.9-2.0-1.91.9-1.9-1.91.9-1.81.8-1.81.8-1.81.8-1.81.50.61.91.9
BMI without tail2.57.611.8-3.4-3.3-3.2-1.8-2.02.72.82.9-2.9-2.9-2.92.9-2.8-2.92.8-2.82.8-2.82.8-2.82.8-2.81.7-0.92.82.8
Body weight1.66.918.4-4.3-4.1-3.6-3.3-0.12.02.52.4-2.6-2.6-2.62.6-2.6-2.62.4-2.42.4-2.42.4-2.42.4-2.40.4-2.42.52.5
Weight adjusted by age1.42.15.3-2.3-1.9-1.9-2.1-0.41.01.31.4-1.5-1.5-1.61.6-1.2-1.51.3-1.21.2-1.21.2-1.21.2-1.20.0-1.81.41.4
Bone surface0.20.40.8-0.2-0.10.2-0.80.1-0.5-0.6-0.60.60.60.6-0.60.50.7-0.70.7-0.70.7-0.70.7-0.70.7-0.6-0.9-0.7-0.7
Bone volume0.00.11.0-0.3-0.2-0.2-0.5-1.00.1-0.1-0.00.00.00.1-0.1-0.00.1-0.20.2-0.20.2-0.20.2-0.20.20.2-0.4-0.2-0.2
Breakpoint value in progressive ratio session0.70.81.1-1.0-0.7-1.0-0.1-1.01.01.00.9-1.0-1.0-1.01.0-1.1-1.01.0-0.90.9-0.90.9-0.90.9-0.90.90.21.01.0
Number of licking bursts0.10.10.3-0.5-0.5-0.5-0.40.30.20.30.3-0.3-0.3-0.40.4-0.3-0.40.4-0.40.4-0.40.4-0.40.4-0.4-0.0-0.40.40.4
Context. condit. distance diff. score2.32.73.8-0.7-0.8-1.50.6-0.51.81.91.8-1.9-1.9-1.91.9-1.9-1.91.9-1.71.7-1.71.7-1.71.7-1.71.71.51.71.7
Locomotion velocity, session 15.35.77.82.12.22.50.52.5-2.8-2.7-2.62.52.52.5-2.52.62.5-2.52.5-2.52.5-2.52.5-2.52.5-2.1-0.4-2.4-2.4
Locomotion distance, session 10.50.63.81.61.51.11.9-0.4-0.3-0.4-0.20.30.30.2-0.20.40.3-0.30.5-0.50.5-0.50.5-0.50.50.51.5-0.3-0.3
Locomotion velocity, session 24.45.17.52.72.72.71.70.4-2.3-2.5-2.22.42.32.3-2.32.42.3-2.32.4-2.42.4-2.42.4-2.42.4-1.10.7-2.3-2.3
Locomotion distance, session 20.30.43.50.60.60.21.1-1.90.60.40.6-0.3-0.4-0.40.4-0.2-0.40.4-0.30.3-0.30.3-0.30.3-0.31.01.10.40.4
Locomotion velocity, session 32.12.33.01.41.51.60.51.3-1.7-1.7-1.61.61.61.5-1.51.61.5-1.61.7-1.71.7-1.71.7-1.71.7-1.20.1-1.5-1.5
Locomotion distance, session 31.82.04.82.22.21.91.80.6-1.2-1.3-1.21.31.31.3-1.31.31.3-1.31.4-1.41.4-1.41.4-1.41.4-0.41.3-1.3-1.3
Stereotopy head waving bouts, day 30.50.60.80.50.70.80.10.7-0.9-0.8-0.80.80.80.9-0.90.80.9-0.90.8-0.80.8-0.80.8-0.80.8-0.6-0.0-0.8-0.8
Stereotopy head waving duration, day 30.20.30.40.40.60.60.30.5-0.4-0.4-0.50.40.50.6-0.60.40.6-0.60.5-0.50.5-0.50.5-0.50.5-0.10.4-0.5-0.5
Locomotion velocity, session 70.30.41.31.11.10.81.10.8-0.5-0.4-0.30.40.40.3-0.30.40.3-0.30.5-0.50.5-0.50.5-0.50.50.11.1-0.5-0.5
Locomotion distance, session 71.01.39.02.01.90.93.0-1.10.60.40.7-0.4-0.4-0.60.6-0.2-0.50.4-0.40.4-0.40.4-0.40.4-0.41.82.80.40.4
Stereotopy head waving bouts, day 70.40.50.8-0.8-0.8-0.9-0.50.60.30.50.6-0.7-0.7-0.80.8-0.7-0.80.7-0.70.7-0.70.7-0.70.7-0.70.0-0.20.70.7
Stereotopy head waving duration, day 70.20.31.2-1.0-0.9-0.8-1.11.00.00.20.2-0.4-0.3-0.30.3-0.4-0.30.3-0.30.3-0.30.3-0.30.3-0.3-0.5-0.80.30.3
Locomotion velocity, session 80.50.62.60.40.3-0.21.31.00.50.70.8-0.9-0.9-0.90.9-0.8-0.90.9-0.60.6-0.60.6-0.60.6-0.60.91.60.70.7
Locomotion distance, session 83.45.08.2-0.4-0.6-1.61.5-2.32.62.42.5-2.5-2.5-2.52.5-2.4-2.52.4-2.22.2-2.22.2-2.22.2-2.22.92.42.22.2
Degree of sensitization distance2.42.53.4-0.9-1.0-1.40.2-1.81.91.81.7-1.7-1.6-1.71.7-1.6-1.71.6-1.71.7-1.71.7-1.71.7-1.71.80.81.61.6
Degree of sensitization stereotypy1.01.11.5-0.9-0.9-1.2-0.3-0.10.91.01.1-1.2-1.2-1.21.2-1.1-1.21.1-1.11.1-1.11.1-1.11.1-1.10.5-0.01.11.1
Conditioned locomotion5.15.87.4-2.3-2.6-2.7-1.1-1.52.42.42.5-2.5-2.6-2.52.5-2.5-2.62.6-2.72.7-2.72.7-2.72.7-2.71.60.12.62.6
Cocaine response after cond. corrected0.10.10.20.40.40.40.30.4-0.2-0.3-0.30.20.30.4-0.40.20.4-0.30.3-0.30.3-0.30.3-0.30.3-0.00.1-0.5-0.5
Cocaine response after cond. not corrected0.70.91.31.11.11.10.60.9-0.8-0.9-0.90.90.91.0-1.00.81.0-1.01.0-1.01.0-1.01.0-1.01.0-0.40.2-1.1-1.1
Cocaine response before conditioning0.60.71.11.01.11.00.71.0-1.0-0.9-0.90.80.80.8-0.80.90.8-0.80.8-0.80.8-0.80.8-0.80.8-0.50.5-0.8-0.8
Saline control response1.01.33.5-1.9-1.7-1.6-1.6-0.31.01.20.9-1.0-1.0-1.01.0-1.0-1.01.0-1.11.1-1.11.1-1.11.1-1.10.1-0.91.21.2
Bone: connectivity density0.10.10.70.30.40.30.7-0.70.30.10.0-0.00.00.1-0.1-0.10.1-0.00.2-0.20.2-0.20.2-0.20.20.40.8-0.1-0.1
Bone: cortical apparent density1.11.54.42.12.01.72.0-0.6-0.9-1.1-1.01.11.11.0-1.01.11.0-1.01.1-1.11.1-1.11.1-1.11.10.11.7-1.1-1.1
Bone: cortical area1.93.012.9-3.2-3.2-2.5-3.60.70.81.11.1-1.3-1.3-1.31.3-1.2-1.31.2-1.21.2-1.21.2-1.21.2-1.2-0.9-2.91.11.1
Bone: cortical porosity1.11.22.9-0.6-0.30.2-1.50.9-1.1-1.0-1.11.01.01.1-1.10.91.1-1.11.1-1.11.1-1.11.1-1.11.1-1.4-1.7-1.1-1.1
Bone: cortical porosity0.60.72.9-1.0-0.8-0.2-1.71.1-0.7-0.5-0.70.50.60.7-0.70.50.6-0.70.6-0.60.6-0.60.6-0.60.6-1.2-1.7-0.6-0.6
Bone: cortical thickness1.62.712.7-3.1-3.1-2.3-3.6-0.00.71.01.0-1.1-1.1-1.21.2-1.0-1.21.2-1.11.1-1.11.1-1.11.1-1.1-0.9-3.01.11.1
Bone: cortical thickness0.70.82.4-1.4-1.6-1.2-1.40.20.60.80.8-0.9-0.9-0.90.9-0.8-0.80.9-0.80.8-0.80.8-0.80.8-0.8-0.3-1.20.70.7
Bone: cortical tissue density1.31.84.82.22.11.82.1-0.6-1.0-1.2-1.11.31.21.1-1.11.21.1-1.11.2-1.21.2-1.21.2-1.21.20.01.8-1.2-1.2
Condit. Reinf. active minus inactive responses1.71.93.6-1.8-1.9-1.7-1.2-0.91.61.61.2-1.5-1.3-1.51.5-1.4-1.51.4-1.31.3-1.31.3-1.31.3-1.30.6-0.61.31.3
Condit. Reinf. active-inactive response ratio1.51.62.2-1.2-1.4-1.3-0.5-0.81.41.51.2-1.4-1.3-1.41.4-1.4-1.41.4-1.31.3-1.31.3-1.31.3-1.30.90.01.31.3
Condit. Reinf. active responses2.32.96.1-2.4-2.5-2.2-1.8-1.41.81.81.5-1.7-1.6-1.81.8-1.7-1.71.7-1.61.6-1.61.6-1.61.6-1.60.7-0.91.51.5
Condit. Reinf. inactive responses0.40.41.1-1.1-1.0-1.0-0.9-1.00.70.60.5-0.6-0.6-0.60.6-0.6-0.60.6-0.60.6-0.60.6-0.60.6-0.60.2-0.50.50.5
Incentive salience index mean1.21.53.2-1.7-1.8-1.6-1.3-0.71.31.31.1-1.2-1.1-1.31.3-1.2-1.31.3-1.21.2-1.21.2-1.21.2-1.20.4-0.71.11.1
Condit. Reinf. lever presses0.40.50.7-0.4-0.4-0.60.0-0.90.70.60.7-0.7-0.6-0.80.8-0.6-0.80.8-0.80.8-0.80.8-0.80.8-0.80.60.30.70.7
Condit. Reinf. active minus inactive responses0.60.81.3-1.0-1.1-1.1-0.80.60.71.00.8-0.9-0.8-1.01.0-1.0-1.01.0-0.90.9-0.90.9-0.90.9-0.90.1-0.10.90.9
Condit. Reinf. active-inactive response ratio0.60.73.2-1.7-1.7-1.2-1.80.40.50.70.5-0.6-0.5-0.60.6-0.7-0.60.6-0.50.5-0.50.5-0.50.5-0.5-0.5-1.30.50.5
Condit. Reinf. active responses1.01.31.7-0.4-0.6-0.90.4-0.51.21.31.3-1.2-1.2-1.31.3-1.2-1.31.3-1.31.3-1.31.3-1.31.3-1.31.01.11.31.3
Condit. Reinf. inactive responses0.60.84.30.90.70.11.7-0.90.60.50.7-0.6-0.6-0.60.6-0.5-0.60.7-0.80.8-0.80.8-0.80.8-0.81.32.10.70.7
Condit. Reinf. lever presses2.63.64.8-0.7-0.8-1.50.8-2.02.12.12.1-1.9-1.9-2.02.0-2.0-2.02.0-2.02.0-2.02.0-2.02.0-2.02.21.71.91.9
Condit. Reinf. lever reinforcers received1.82.53.2-0.4-0.6-1.20.8-1.01.71.81.7-1.7-1.6-1.71.7-1.7-1.71.8-1.81.8-1.81.8-1.81.8-1.81.71.81.71.7
Conditioned reinforcement - actives0.00.11.00.10.50.10.3-1.00.30.30.00.10.10.0-0.0-0.10.00.10.0-0.00.0-0.00.0-0.00.00.70.30.00.0
Conditioned reinforcement - inactives0.50.71.5-1.1-1.2-1.1-1.0-0.40.50.80.8-0.6-0.7-0.80.8-0.8-0.80.9-0.90.9-0.90.9-0.90.9-0.90.3-0.60.90.9
Conditioned locomotion0.40.51.7-1.0-0.8-0.7-0.5-1.31.11.20.6-0.6-0.6-0.70.7-0.7-0.70.7-0.60.6-0.60.6-0.60.6-0.61.00.00.50.5
Patch foraging indifference point 0 sec1.01.88.0-1.2-0.9-1.20.0-2.81.41.21.4-1.2-1.2-1.31.3-1.1-1.31.2-1.41.4-1.41.4-1.41.4-1.41.40.71.31.3
Patch foraging indifference point AUC0.10.20.4-0.5-0.4-0.40.2-0.20.50.50.6-0.6-0.6-0.30.3-0.6-0.40.5-0.30.3-0.30.3-0.30.3-0.30.40.10.40.4
Delay disc. indifference point, 0s delay0.10.12.7-0.10.2-0.2-0.31.7-0.10.30.0-0.2-0.2-0.00.0-0.2-0.10.00.1-0.10.1-0.10.1-0.10.1-0.4-0.1-0.1-0.1
Delay disc. indifference point, 16s delay0.40.53.10.80.80.11.70.0-0.1-0.20.5-0.5-0.4-0.50.5-0.5-0.50.4-0.50.5-0.50.5-0.50.5-0.50.61.80.60.6
Delay disc. indifference point, 2s delay0.30.32.60.10.40.3-0.01.6-1.0-0.6-0.20.30.20.3-0.30.30.3-0.40.4-0.40.4-0.40.4-0.40.4-1.0-0.1-0.3-0.3
Delay disc. indifference point, 24s delay3.23.66.22.52.12.31.31.3-2.3-2.4-1.71.81.92.0-2.01.82.0-2.01.9-1.91.9-1.91.9-1.91.9-1.40.4-1.8-1.8
Delay disc. indifference point, 4s delay0.20.23.60.10.40.10.31.9-0.7-0.4-0.0-0.1-0.00.2-0.2-0.10.2-0.30.3-0.30.3-0.30.3-0.30.3-0.70.4-0.2-0.2
Delay disc. indifference point, 8s delay1.92.211.31.01.01.40.13.4-1.9-1.6-1.41.21.31.4-1.41.21.4-1.41.4-1.41.4-1.41.4-1.41.4-1.9-0.5-1.3-1.3
Indifference point function ln k0.20.41.81.21.20.91.3-1.0-0.0-0.3-0.30.40.40.3-0.30.30.4-0.40.3-0.30.3-0.30.3-0.30.30.61.3-0.4-0.4
Indifference point function log k0.20.41.81.21.20.91.3-1.0-0.0-0.3-0.30.40.40.3-0.30.30.4-0.40.3-0.30.3-0.30.3-0.30.30.61.3-0.4-0.4
Patch foraging total patch changes 0 sec1.42.69.6-1.2-1.0-1.40.2-3.11.71.51.7-1.5-1.5-1.71.7-1.5-1.61.5-1.71.7-1.71.7-1.71.7-1.71.81.01.61.6
Patch foraging total patch changes 12 sec0.60.75.6-1.0-0.8-0.9-0.1-2.40.70.50.8-0.8-0.8-0.60.6-0.8-0.60.6-0.80.8-0.80.8-0.80.8-0.80.80.10.80.8
Patch foraging total patch changes 18 sec1.72.64.8-0.7-0.5-1.31.2-2.21.61.41.8-1.8-1.7-1.71.7-1.6-1.71.6-1.71.7-1.71.7-1.71.7-1.71.91.81.71.7
Patch foraging total patch changes 24 sec1.22.03.8-2.0-1.7-1.7-0.9-1.01.51.71.5-1.5-1.6-1.51.5-1.5-1.41.5-1.41.4-1.41.4-1.41.4-1.40.9-0.31.41.4
Patch foraging total patch changes 6 sec0.40.65.6-1.4-1.2-0.9-1.0-2.40.60.40.6-0.5-0.5-0.40.4-0.5-0.30.3-0.40.4-0.40.4-0.40.4-0.40.2-0.90.30.3
Patch foraging time to switch 0 sec0.61.32.01.41.41.30.70.9-1.3-1.3-1.21.11.11.1-1.11.21.1-1.21.1-1.11.1-1.11.1-1.11.1-1.10.1-1.0-1.0
Patch foraging water rate 0 sec3.77.99.7-3.0-2.9-3.1-1.1-1.92.93.03.1-3.0-3.1-3.03.0-3.0-3.03.0-3.03.0-3.03.0-3.03.0-3.02.30.12.92.9
Patch foraging water rate 12 sec1.73.66.4-0.8-0.9-1.50.6-1.92.32.12.1-1.9-2.0-2.12.1-1.9-2.12.1-2.02.0-2.02.0-2.02.0-2.02.51.52.02.0
Patch foraging water rate 18 sec2.53.96.0-1.6-1.5-1.9-0.1-2.32.42.32.3-2.1-2.2-2.02.0-2.2-2.02.0-2.02.0-2.02.0-2.02.0-2.02.40.81.91.9
Patch foraging water rate 24 sec9.513.416.6-2.6-2.6-3.50.2-3.64.03.84.1-4.0-4.0-3.93.9-4.0-3.93.8-3.83.8-3.83.8-3.83.8-3.83.91.73.93.9
Patch foraging water rate 6 sec0.60.92.2-0.7-0.5-0.70.4-0.81.41.51.2-1.1-1.1-0.90.9-1.2-0.91.2-0.80.8-0.80.8-0.80.8-0.81.30.70.80.8
Seeking ratio, delayed vs. immediate footshock0.20.31.8-0.9-0.2-0.6-1.10.20.20.30.0-0.2-0.1-0.20.2-0.1-0.20.3-0.40.4-0.40.4-0.40.4-0.4-0.7-1.30.40.4
Distance traveled before self-admin0.71.01.6-1.2-1.2-1.3-1.00.20.70.81.0-1.0-1.1-1.11.1-0.9-1.11.0-1.01.0-1.01.0-1.01.0-1.0-0.0-0.81.01.0
Distance traveled after self-admin2.22.74.1-1.2-1.2-1.60.0-2.02.01.71.7-1.7-1.6-1.71.7-1.7-1.71.8-1.81.8-1.81.8-1.81.8-1.81.80.81.61.6
Extensor digitorum longus weight1.04.07.0-0.4-0.6-1.41.3-2.72.42.12.1-2.1-2.1-2.12.1-2.1-2.12.1-2.12.1-2.12.1-2.12.1-2.12.41.72.12.1
Bone: elastic displacement1.01.22.7-1.6-1.6-1.4-1.3-1.41.11.00.9-1.0-1.0-1.01.0-1.0-1.11.1-1.01.0-1.01.0-1.01.0-1.00.5-0.41.01.0
Bone: elastic work1.82.312.0-3.3-3.1-2.3-3.5-0.60.81.00.8-1.0-1.0-1.01.0-1.0-1.01.0-0.80.8-0.80.8-0.80.8-0.8-0.6-2.50.90.9
Bone: endosteal estimation0.10.20.50.20.1-0.10.60.00.50.40.6-0.6-0.6-0.40.4-0.5-0.40.4-0.40.4-0.40.4-0.40.4-0.40.60.70.30.3
Bone: endosteal perimeter0.20.53.4-1.0-0.9-0.5-1.71.9-0.5-0.3-0.20.10.10.2-0.20.20.2-0.20.2-0.20.2-0.20.2-0.20.2-1.2-1.6-0.3-0.3
Epididymis fat weight1.34.66.6-2.2-2.4-2.4-1.0-0.82.52.62.4-2.3-2.3-2.32.3-2.5-2.32.4-2.12.1-2.12.1-2.12.1-2.11.7-0.22.22.2
Delta time in closed arm before/after self-admin0.00.00.2-0.2-0.1-0.1-0.30.40.00.30.1-0.1-0.10.1-0.1-0.10.00.1-0.10.1-0.10.1-0.10.1-0.1-0.00.00.10.1
Delta time in open arm before/after self-admin0.40.41.9-0.7-0.5-0.70.1-1.40.60.50.6-0.7-0.5-0.80.8-0.8-0.80.6-0.60.6-0.60.6-0.60.6-0.60.60.10.60.6
Diff in mean of infusions in LGA sessions0.20.20.6-0.7-0.7-0.8-0.60.0-0.10.20.3-0.3-0.4-0.40.4-0.4-0.40.3-0.50.5-0.50.5-0.50.5-0.5-0.2-0.60.60.6
Delay discount exponential model param1.21.46.1-1.2-1.3-1.2-1.0-2.51.71.50.9-0.8-0.9-1.01.0-0.8-1.01.1-1.01.0-1.01.0-1.01.0-1.01.2-0.70.90.9
Extinction: sum of active levers before priming0.20.20.70.50.40.60.8-0.4-0.0-0.1-0.20.20.30.5-0.50.10.5-0.30.4-0.40.4-0.40.4-0.40.40.50.9-0.5-0.5
Active lever presses in extinction session 60.00.00.2-0.4-0.2-0.3-0.2-0.2-0.3-0.40.1-0.0-0.1-0.30.30.0-0.30.1-0.10.1-0.10.1-0.10.1-0.1-0.2-0.30.20.2
Bone: final force2.23.511.4-3.4-3.1-2.7-3.00.11.41.71.5-1.8-1.8-1.71.7-1.7-1.61.6-1.61.6-1.61.6-1.61.6-1.6-0.2-2.11.51.5
Bone: final moment2.64.113.3-3.6-3.4-2.9-3.3-0.21.51.81.7-1.9-1.9-1.81.8-1.8-1.81.7-1.71.7-1.71.7-1.71.7-1.7-0.1-2.41.61.6
Food consumed during 24 hour testing period1.52.13.0-1.2-1.7-1.5-0.6-0.21.41.61.5-1.5-1.5-1.61.6-1.5-1.61.7-1.61.6-1.61.6-1.61.6-1.61.00.11.61.6
Glucose8.813.916.93.53.64.01.32.2-3.9-4.1-3.94.04.04.0-4.04.04.0-3.94.1-4.14.1-4.14.1-4.14.1-2.70.0-4.0-4.0
Heart weight0.20.31.8-1.1-1.2-0.6-1.30.50.40.30.1-0.3-0.2-0.30.3-0.3-0.30.4-0.30.3-0.30.3-0.30.3-0.3-0.2-0.80.20.2
Delay discount hyperbolic model param1.11.26.0-1.1-1.1-1.1-0.9-2.41.71.40.8-0.7-0.8-0.90.9-0.7-0.91.0-1.01.0-1.01.0-1.01.0-1.01.2-0.60.90.9
Intermittent access intake day 1-15 change0.00.00.8-0.20.0-0.1-0.30.9-0.1-0.10.10.0-0.1-0.00.00.0-0.0-0.00.1-0.10.1-0.10.1-0.10.1-0.3-0.30.10.1
Intermittent access intake escalation0.00.00.6-0.20.10.0-0.30.8-0.1-0.00.00.1-0.00.0-0.00.10.0-0.00.1-0.10.1-0.10.1-0.10.1-0.2-0.30.00.0
Intermittent access intake escalation 20.10.10.9-0.5-0.3-0.1-0.81.0-0.2-0.1-0.10.20.10.1-0.10.10.1-0.20.2-0.20.2-0.20.2-0.20.2-0.5-0.8-0.1-0.1
Intermitt. access day 1 inactive lever presses1.45.48.6-2.4-2.9-2.8-1.2-1.72.12.32.5-2.4-2.5-2.42.4-2.5-2.42.4-2.52.5-2.52.5-2.52.5-2.51.7-0.22.42.4
Intermitt. access day 15 inactive lever presses1.32.63.6-1.5-1.3-1.7-0.2-1.31.91.91.7-1.7-1.8-1.71.7-1.8-1.71.7-1.71.7-1.71.7-1.71.7-1.71.40.51.71.7
Intermitt. access escalation Index0.50.71.1-1.0-1.0-1.0-0.7-0.70.90.70.8-0.9-0.9-0.80.8-0.9-0.80.9-0.80.8-0.80.8-0.80.8-0.80.3-0.30.80.8
Intermittent access day 1 total infusions0.10.11.5-0.4-0.2-0.2-0.2-1.20.50.60.2-0.2-0.2-0.20.2-0.3-0.20.2-0.20.2-0.20.2-0.20.2-0.20.60.00.00.0
Intermittent access day 15 total infusions0.10.20.8-0.9-0.5-0.5-0.7-0.40.40.60.4-0.3-0.4-0.40.4-0.4-0.40.4-0.30.3-0.30.3-0.30.3-0.30.3-0.50.30.3
Intermittent access terminal intake (last 3 days)0.10.10.9-1.0-0.4-0.4-0.9-0.20.40.50.3-0.2-0.2-0.20.2-0.3-0.20.3-0.10.1-0.10.1-0.10.1-0.10.1-0.70.20.2
Intermittent access total infusions0.10.10.6-0.8-0.2-0.3-0.5-0.60.40.60.3-0.2-0.3-0.30.3-0.4-0.30.3-0.20.2-0.20.2-0.20.2-0.20.4-0.30.20.2
Intermittent access day 1 locomotion0.10.10.9-0.6-0.7-0.3-0.5-1.00.30.50.1-0.2-0.2-0.20.2-0.3-0.20.3-0.30.3-0.30.3-0.30.3-0.30.5-0.10.20.2
Intermittent access day 15 total locomotion0.20.31.1-1.1-0.9-0.7-1.00.10.50.70.5-0.5-0.5-0.50.5-0.6-0.50.5-0.40.4-0.40.4-0.40.4-0.40.3-0.60.50.5
Intermittent access total locomotion0.20.30.8-0.9-0.7-0.6-0.6-0.40.40.60.4-0.5-0.4-0.50.5-0.6-0.50.5-0.50.5-0.50.5-0.50.5-0.50.5-0.30.50.5
Intermittent access standard deviation0.20.56.10.40.50.5-0.02.5-0.9-0.5-0.50.60.40.5-0.50.50.5-0.40.5-0.50.5-0.50.5-0.50.5-0.9-0.2-0.5-0.5
Left kidney weight0.10.74.1-0.5-0.40.1-1.12.0-1.0-0.6-0.60.50.50.6-0.60.30.6-0.70.8-0.80.8-0.80.8-0.80.8-1.2-1.2-0.9-0.9
Right kidney weight0.10.52.2-0.4-0.50.1-1.01.5-0.7-0.5-0.50.30.40.5-0.50.20.5-0.50.8-0.80.8-0.80.8-0.80.8-1.0-1.0-0.8-0.8
Cocaine induced anxiety0.50.74.4-1.3-1.4-1.0-2.01.0-0.3-0.10.2-0.3-0.3-0.30.3-0.2-0.30.2-0.50.5-0.50.5-0.50.5-0.5-1.1-2.10.20.2
Post-drug Anxiety0.10.20.6-0.4-0.6-0.4-0.50.6-0.8-0.70.1-0.1-0.1-0.10.1-0.0-0.1-0.0-0.30.3-0.30.3-0.30.3-0.3-0.6-0.80.10.1
Baseline Anxiety0.80.93.21.41.41.21.8-0.5-0.9-1.3-0.60.70.70.9-0.90.60.9-0.80.8-0.80.8-0.80.8-0.80.80.31.4-0.7-0.7
Tail length1.55.820.4-4.5-4.3-3.4-4.1-0.31.62.01.8-2.1-2.1-2.02.0-2.2-2.01.9-2.02.0-2.02.0-2.02.0-2.0-0.2-3.31.91.9
Length with tail0.62.717.3-3.6-3.2-2.1-4.21.8-0.10.60.1-0.5-0.4-0.40.4-0.7-0.40.3-0.30.3-0.30.3-0.30.3-0.3-1.9-4.00.30.3
Length without tail0.41.25.2-1.2-1.1-0.3-2.12.3-0.9-0.4-0.90.50.60.7-0.70.40.6-0.70.8-0.80.8-0.80.8-0.80.8-1.9-2.2-0.8-0.8
Times rat made contact with spout0.40.52.5-1.3-1.6-0.9-1.5-0.80.60.50.3-0.4-0.3-0.40.4-0.4-0.40.4-0.40.4-0.40.4-0.40.4-0.40.1-0.70.50.5
Lifetime Intake0.00.00.2-0.30.1-0.0-0.1-0.30.30.40.2-0.0-0.1-0.10.1-0.2-0.10.1-0.00.0-0.00.0-0.00.0-0.00.40.10.00.0
Liver weight, left0.91.52.10.91.21.10.00.8-1.5-1.4-1.31.41.41.4-1.41.41.3-1.41.3-1.31.3-1.31.3-1.31.3-1.2-0.3-1.4-1.4
Liver weight, right1.32.27.9-2.8-2.5-2.3-2.7-0.31.01.31.2-1.2-1.3-1.31.3-1.3-1.31.2-1.21.2-1.21.2-1.21.2-1.2-0.3-1.81.11.1
Locomotor activity0.30.41.00.81.00.80.8-0.1-0.2-0.3-0.60.60.60.7-0.70.50.7-0.60.6-0.60.6-0.60.6-0.60.60.20.8-0.6-0.6
Locomotor testing distance0.10.22.20.71.00.51.3-0.20.20.1-0.10.10.10.2-0.20.10.1-0.10.0-0.00.0-0.00.0-0.00.00.71.5-0.0-0.0
Locomotor testing rearing0.91.72.9-0.4-0.3-0.80.9-1.31.51.31.3-1.2-1.3-1.31.3-1.3-1.31.3-1.41.4-1.41.4-1.41.4-1.41.71.71.51.5
Locomotion in novel chamber0.10.20.6-0.4-0.6-0.3-0.1-0.80.60.60.5-0.5-0.4-0.40.4-0.7-0.30.3-0.10.1-0.10.1-0.10.1-0.10.60.20.30.3
Locomotion in novel chamber post-restriction0.30.42.4-1.1-1.4-0.9-1.6-0.60.40.40.3-0.3-0.1-0.50.5-0.2-0.50.3-0.40.4-0.40.4-0.40.4-0.4-0.0-1.40.40.4
Fecal boli incidents, locomotor time 10.10.21.01.00.90.70.4-0.50.1-0.1-0.20.50.30.3-0.30.60.3-0.30.3-0.30.3-0.30.3-0.30.30.10.2-0.4-0.4
Change in fecal boli incidents, locomotor task2.62.63.81.62.01.81.40.1-1.8-1.9-1.51.51.51.7-1.71.51.7-1.81.8-1.81.8-1.81.8-1.81.8-0.80.5-1.6-1.6
Time >=10cm from walls, locomotor time 10.80.91.5-0.1-0.0-0.60.70.20.91.01.0-1.0-0.9-1.01.0-0.9-1.01.1-1.01.0-1.01.0-1.01.0-1.01.11.21.11.1
Bouts of movement, locomotor time 11.21.32.41.51.31.61.10.4-0.8-0.9-1.21.21.21.2-1.21.11.2-1.11.3-1.31.3-1.31.3-1.31.3-0.20.6-1.1-1.1
Total resting periods, locomotor time 12.02.23.71.71.51.91.10.2-1.1-1.3-1.61.61.61.6-1.61.41.6-1.51.7-1.71.7-1.71.7-1.71.7-0.40.5-1.6-1.6
Rest time, locomotor task time 11.82.23.20.90.81.5-0.20.4-1.1-1.1-1.61.71.71.7-1.71.51.7-1.71.7-1.71.7-1.71.7-1.71.7-1.1-0.6-1.8-1.8
Distance moved, locomotor task time 10.91.32.2-1.2-0.9-1.5-0.5-0.30.50.71.3-1.3-1.3-1.41.4-1.0-1.41.2-1.31.3-1.31.3-1.31.3-1.30.4-0.31.51.5
Vertical activity count, locomotor time 10.92.23.3-1.0-1.0-1.6-0.3-0.51.51.61.7-1.6-1.6-1.71.7-1.2-1.71.7-1.71.7-1.71.7-1.71.7-1.71.20.71.81.8
Time >=10cm from walls, locomotor time 20.00.00.1-0.20.2-0.2-0.3-0.3-0.3-0.20.1-0.2-0.1-0.00.0-0.0-0.0-0.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.30.10.1
Bouts of movement, locomotor time 20.40.71.81.30.91.21.10.8-0.7-0.8-0.90.80.80.8-0.80.80.8-0.70.8-0.80.8-0.80.8-0.80.8-0.20.8-0.8-0.8
Total resting periods, locomotor time 20.20.40.91.00.60.90.90.7-0.4-0.5-0.70.50.60.6-0.60.50.6-0.50.5-0.50.5-0.50.5-0.50.5-0.00.7-0.6-0.6
Rest time, locomotor task time 20.40.40.70.30.00.6-0.20.7-0.5-0.6-0.80.70.80.8-0.80.60.8-0.70.7-0.70.7-0.70.7-0.70.7-0.3-0.2-0.9-0.9
Distance moved, locomotor task time 20.20.30.8-0.9-0.2-0.8-0.6-0.0-0.10.30.5-0.5-0.5-0.60.6-0.3-0.60.4-0.50.5-0.50.5-0.50.5-0.5-0.4-0.50.70.7
Vertical activity count, locomotor time 20.50.61.1-0.5-0.3-0.9-0.1-0.20.80.90.8-0.9-0.8-0.90.9-0.6-0.90.9-0.90.9-0.90.9-0.90.9-0.90.40.61.11.1
Light reinforcement 11.84.37.0-1.8-1.9-2.2-0.6-2.52.62.62.0-2.1-2.1-2.02.0-2.2-2.02.1-2.22.2-2.22.2-2.22.2-2.22.00.42.12.1
Light reinforcement 21.11.73.4-1.6-1.9-1.7-1.6-0.41.31.41.1-1.3-1.2-1.21.2-1.3-1.31.3-1.31.3-1.31.3-1.31.3-1.30.5-0.91.31.3
Bone: marrow area0.10.20.60.20.1-0.10.60.00.50.50.6-0.6-0.6-0.50.5-0.5-0.40.4-0.40.4-0.40.4-0.40.4-0.40.60.70.40.4
Bone: maximum diameter0.51.06.0-1.8-1.7-1.1-2.52.2-0.30.10.2-0.3-0.3-0.30.3-0.1-0.30.2-0.20.2-0.20.2-0.20.2-0.2-1.4-2.20.10.1
Bone: maximum force2.03.611.3-3.4-3.1-2.7-2.9-0.31.41.71.6-1.8-1.7-1.71.7-1.7-1.71.6-1.61.6-1.61.6-1.61.6-1.6-0.1-2.21.61.6
Bone: maximum moment2.34.012.8-3.6-3.3-2.8-3.2-0.61.51.71.7-1.8-1.8-1.81.8-1.7-1.81.7-1.71.7-1.71.7-1.71.7-1.7-0.0-2.41.71.7
Mean time between licks in bursts0.30.71.61.31.11.10.90.9-1.0-1.0-0.90.90.90.8-0.80.90.8-0.70.7-0.70.7-0.70.7-0.70.7-0.40.2-0.8-0.8
Mean num. licks in bursts0.10.21.8-0.5-0.7-0.4-0.4-1.30.50.40.3-0.3-0.4-0.30.3-0.3-0.30.2-0.30.3-0.30.3-0.30.3-0.30.40.30.30.3
Cd content in liver1.82.03.90.30.1-0.61.6-1.91.61.31.5-1.4-1.4-1.41.4-1.4-1.41.4-1.41.4-1.41.4-1.41.4-1.42.01.81.41.4
Co content in liver0.00.00.3-0.1-0.20.0-0.3-0.60.10.0-0.20.10.10.2-0.20.00.2-0.00.1-0.10.1-0.10.1-0.10.10.0-0.5-0.1-0.1
Cu content in liver0.20.21.7-0.9-0.8-0.4-1.30.3-0.10.1-0.20.20.20.1-0.10.00.1-0.00.1-0.10.1-0.10.1-0.10.1-0.4-1.10.00.0
Fe content in liver0.30.41.10.20.3-0.11.0-0.60.50.40.8-0.7-0.7-0.50.5-0.7-0.50.5-0.60.6-0.60.6-0.60.6-0.61.00.90.50.5
K content in liver1.51.42.2-1.3-1.5-1.3-0.8-0.71.41.51.0-1.1-1.1-1.21.2-1.2-1.21.3-1.31.3-1.31.3-1.31.3-1.30.8-0.11.31.3
Mg content in liver1.21.22.3-0.4-0.7-0.80.3-1.51.51.41.0-1.0-1.0-1.11.1-1.2-1.11.2-1.11.1-1.11.1-1.11.1-1.11.40.71.21.2
Mn content in liver0.10.10.6-0.2-0.2-0.3-0.40.8-0.10.1-0.0-0.0-0.0-0.20.20.0-0.20.3-0.40.4-0.40.4-0.40.4-0.4-0.3-0.10.40.4
Na content in liver0.00.00.1-0.0-0.0-0.1-0.00.10.20.30.1-0.1-0.1-0.20.2-0.1-0.10.2-0.20.2-0.20.2-0.20.2-0.20.20.10.10.1
Rb content in liver3.84.45.7-1.7-1.9-2.1-0.4-1.42.32.42.2-2.2-2.2-2.32.3-2.4-2.32.3-2.22.2-2.22.2-2.22.2-2.21.80.32.32.3
Se content in liver1.01.21.7-0.5-0.6-0.90.2-0.81.11.21.2-1.1-1.1-1.11.1-1.1-1.11.2-1.31.3-1.31.3-1.31.3-1.31.10.61.31.3
Sr content in liver1.00.91.20.40.50.8-0.3-0.1-1.0-1.1-1.01.11.11.0-1.01.11.0-1.11.0-1.01.0-1.01.0-1.01.0-0.8-0.4-1.0-1.0
Zn content in liver0.30.32.0-1.2-1.2-0.7-1.4-0.40.60.70.1-0.2-0.2-0.20.2-0.4-0.20.3-0.10.1-0.10.1-0.10.1-0.1-0.0-1.20.30.3
Bone: minimum diameter1.42.68.3-2.9-2.8-2.3-2.80.01.21.41.3-1.5-1.5-1.31.3-1.4-1.31.3-1.31.3-1.31.3-1.31.3-1.3-0.2-2.21.31.3
Time in familiar zone, hab. session 10.10.10.80.20.1-0.00.4-0.90.10.10.5-0.3-0.3-0.20.2-0.2-0.20.1-0.10.1-0.10.1-0.10.1-0.10.60.30.00.0
Time in novel zone, hab. session 10.10.11.3-0.10.00.1-0.21.10.00.2-0.20.10.10.3-0.3-0.10.3-0.10.3-0.30.3-0.30.3-0.30.3-0.30.1-0.2-0.2
Total zone transitions, hab. session 10.30.41.90.40.4-0.11.2-1.40.70.50.6-0.6-0.5-0.60.6-0.6-0.50.5-0.40.4-0.40.4-0.40.4-0.41.11.10.40.4
Total locomotion distance, hab. session 11.21.73.3-0.7-0.7-1.10.5-1.71.81.81.5-1.6-1.6-1.41.4-1.7-1.31.4-1.21.2-1.21.2-1.21.2-1.21.70.91.21.2
Locomotion velocity, hab. session 11.31.93.5-0.8-0.8-1.20.4-1.91.71.71.5-1.5-1.5-1.61.6-1.6-1.51.5-1.31.3-1.31.3-1.31.3-1.31.60.61.31.3
Time in familiar zone, hab. session 20.20.21.20.40.30.10.9-0.30.30.30.5-0.4-0.4-0.30.3-0.4-0.30.3-0.40.4-0.40.4-0.40.4-0.40.91.10.30.3
Time in novel zone, hab. session 20.10.10.30.20.30.3-0.10.4-0.4-0.4-0.50.40.40.4-0.40.40.4-0.40.4-0.40.4-0.40.4-0.40.4-0.6-0.2-0.3-0.3
Total zone transitions, hab. session 21.51.97.00.20.1-0.61.4-2.71.71.31.4-1.3-1.3-1.31.3-1.2-1.31.3-1.31.3-1.31.3-1.31.3-1.32.01.51.41.4
Total locomotion distance, hab. session 22.22.98.2-0.9-0.9-1.40.4-2.92.31.91.8-1.8-1.8-1.81.8-1.8-1.71.7-1.61.6-1.61.6-1.61.6-1.62.10.91.61.6
Locomotion velocity, hab. session 22.22.97.5-1.1-1.1-1.50.1-2.72.32.11.8-1.8-1.8-1.81.8-1.8-1.81.8-1.61.6-1.61.6-1.61.6-1.61.90.61.61.6
Novel to familiar place preference ratio1.82.06.2-1.7-1.7-1.6-1.1-2.51.61.41.3-1.3-1.3-1.41.4-1.4-1.41.3-1.41.4-1.41.4-1.41.4-1.40.9-0.61.41.4
Novelty place preference1.51.65.1-1.6-1.6-1.5-1.1-2.31.51.21.1-1.1-1.2-1.21.2-1.2-1.21.2-1.21.2-1.21.2-1.21.2-1.20.8-0.71.21.2
Time in novel zone, NPP test1.71.86.0-1.5-1.5-1.5-0.8-2.51.61.31.2-1.3-1.2-1.31.3-1.3-1.31.3-1.31.3-1.31.3-1.31.3-1.31.0-0.41.41.4
Total zone transitions, NPP test0.91.43.40.30.3-0.51.5-1.81.41.11.3-1.2-1.2-1.21.2-1.1-1.21.2-1.01.0-1.01.0-1.01.0-1.01.71.51.11.1
Total locomotion distance, NPP test2.83.811.4-0.5-0.6-1.41.1-3.42.52.12.1-2.1-2.0-2.02.0-2.0-2.02.0-1.91.9-1.91.9-1.91.9-1.92.61.41.91.9
Locomotion velocity, NPP test2.33.39.7-0.7-0.8-1.40.7-3.12.32.02.0-1.9-1.9-1.91.9-1.8-1.91.9-1.71.7-1.71.7-1.71.7-1.72.31.11.81.8
Intraocular pressure0.91.33.1-1.0-1.2-1.00.1-1.81.41.31.2-1.3-1.3-1.11.1-1.5-1.11.1-1.01.0-1.01.0-1.01.0-1.01.20.31.01.0
Delta distance traveled before/after self-admin0.50.52.3-0.00.1-0.21.0-1.51.10.80.6-0.6-0.4-0.50.5-0.7-0.50.6-0.60.6-0.60.6-0.60.6-0.61.51.40.40.4
Delta ambulatory time before/after self-admin0.40.43.00.70.90.51.5-1.40.60.30.1-0.00.10.0-0.0-0.20.00.10.0-0.00.0-0.00.0-0.00.01.41.7-0.1-0.1
Parametrial fat weight0.51.32.5-1.2-1.6-1.3-0.9-1.11.21.11.2-1.2-1.1-1.21.2-1.1-1.21.1-1.11.1-1.11.1-1.11.1-1.11.0-0.41.11.1
Pavlov. Cond. lever latency1.51.97.61.11.00.02.5-0.61.51.51.3-1.2-1.2-1.11.1-1.3-1.11.2-1.11.1-1.11.1-1.11.1-1.12.22.81.11.1
Pavlov. Cond. magazine entry latency0.70.95.8-1.9-1.6-1.1-2.41.2-0.30.1-0.1-0.1-0.1-0.20.2-0.0-0.20.1-0.30.3-0.30.3-0.30.3-0.3-1.3-2.20.20.2
Pavlov. Cond. change in total contacts0.20.20.7-0.5-0.4-0.0-0.8-0.8-0.3-0.4-0.50.40.50.4-0.40.30.4-0.40.4-0.40.4-0.40.4-0.40.4-0.5-0.8-0.4-0.4
Pavlov. Cond. index score0.91.28.6-2.3-2.1-1.4-2.90.5-0.2-0.00.0-0.1-0.1-0.20.2-0.1-0.20.1-0.30.3-0.30.3-0.30.3-0.3-1.4-2.70.20.2
Pavlov. Cond. latency score1.01.28.8-2.0-1.8-0.9-3.00.9-0.8-0.5-0.50.40.40.3-0.30.40.3-0.40.2-0.20.2-0.20.2-0.20.2-1.8-2.8-0.3-0.3
Pavlov. Cond. lever contacts0.60.74.1-1.2-1.0-0.3-2.0-0.3-0.7-0.8-0.60.60.60.5-0.50.60.5-0.60.5-0.50.5-0.50.5-0.50.5-1.2-2.0-0.6-0.6
Pavlov. Cond. magazine entry number0.70.96.11.71.50.82.5-1.10.70.40.4-0.3-0.3-0.20.2-0.3-0.20.3-0.10.1-0.10.1-0.10.1-0.11.62.40.20.2
Pavlov. Cond. intertrial magazine entries0.60.73.0-0.1-0.3-0.50.5-1.71.31.00.8-0.9-0.8-0.80.8-0.9-0.80.9-0.60.6-0.60.6-0.60.6-0.61.20.80.70.7
Pavlov. Cond. lever-magazine prob. diff.0.91.17.5-2.3-2.1-1.5-2.70.20.00.20.2-0.4-0.3-0.40.4-0.3-0.40.3-0.50.5-0.50.5-0.50.5-0.5-1.1-2.40.40.4
Pavlov. Cond. response bias0.70.85.6-1.6-1.4-0.7-2.40.7-0.7-0.5-0.50.40.50.4-0.40.50.4-0.40.3-0.30.3-0.30.3-0.30.3-1.6-2.3-0.4-0.4
Pavlov. Cond. lever latency3.54.86.01.41.62.1-0.12.0-2.4-2.4-2.42.32.32.3-2.32.42.3-2.32.4-2.42.4-2.42.4-2.42.4-2.2-1.0-2.3-2.3
Pavlov. Cond. magazine entry latency1.11.45.60.90.7-0.02.3-1.61.21.01.1-1.0-0.9-0.90.9-1.1-0.90.9-0.90.9-0.90.9-0.90.9-0.92.12.40.90.9
Pavlov. Cond. change in total contacts1.32.14.50.2-0.0-0.71.6-2.01.71.61.6-1.4-1.4-1.41.4-1.5-1.41.5-1.41.4-1.41.4-1.41.4-1.42.11.91.31.3
Pavlov. Cond. index score2.12.85.2-0.2-0.4-1.11.3-2.01.91.81.8-1.7-1.7-1.71.7-1.8-1.71.7-1.71.7-1.71.7-1.71.7-1.72.31.91.61.6
Pavlov. Cond. latency score2.12.84.9-0.2-0.4-1.11.3-1.81.91.91.8-1.7-1.7-1.71.7-1.8-1.71.8-1.71.7-1.71.7-1.71.7-1.72.21.81.71.7
Pavlov. Cond. lever contacts3.34.66.0-1.2-1.3-1.90.4-2.32.42.42.3-2.2-2.2-2.22.2-2.3-2.22.3-2.32.3-2.32.3-2.32.3-2.32.31.22.22.2
Pavlov. Cond. magazine entry number1.21.55.1-0.7-0.50.2-2.01.6-1.4-1.2-1.21.11.11.0-1.01.21.0-1.11.0-1.01.0-1.01.0-1.01.0-2.0-2.3-0.9-0.9
Pavlov. Cond. intertrial magazine entries0.91.42.5-1.6-1.6-1.5-1.40.20.91.11.1-1.1-1.2-1.21.2-1.0-1.21.2-1.21.2-1.21.2-1.21.2-1.20.1-0.51.31.3
Pavlov. Cond. lever-magazine prob. diff.1.72.24.80.1-0.1-0.81.5-1.91.71.61.6-1.5-1.5-1.41.4-1.6-1.41.5-1.41.4-1.41.4-1.41.4-1.42.22.01.41.4
Pavlov. Cond. response bias2.23.05.5-0.4-0.6-1.21.1-2.32.11.91.9-1.8-1.8-1.71.7-1.9-1.71.8-1.81.8-1.81.8-1.81.8-1.82.31.71.71.7
Time in closed arm before self-admin0.81.12.60.80.31.00.00.6-1.4-1.6-1.01.11.11.0-1.01.01.0-1.21.1-1.11.1-1.11.1-1.11.1-0.9-0.3-1.1-1.1
Time in closed arm after self-admin1.61.73.31.00.41.30.11.2-1.8-1.7-1.21.31.31.4-1.41.11.4-1.51.4-1.41.4-1.41.4-1.41.4-1.0-0.2-1.3-1.3
Time in open arm before self-admin0.10.10.20.10.3-0.2-0.20.40.30.30.2-0.1-0.2-0.30.30.2-0.30.4-0.40.4-0.40.4-0.40.4-0.4-0.1-0.20.40.4
Time in open arm after self-admin0.50.51.8-0.40.0-0.60.4-1.30.80.60.6-0.6-0.5-0.90.9-0.6-0.90.8-0.80.8-0.80.8-0.80.8-0.80.80.40.80.8
Bone: periosteal estimation0.61.33.9-1.9-1.9-1.6-2.00.60.60.90.9-1.1-1.1-1.01.0-0.9-0.90.9-0.90.9-0.90.9-0.90.9-0.9-0.3-1.50.80.8
Bone: periosteal perimeter1.22.113.7-2.3-2.1-1.0-3.72.4-1.1-0.6-0.60.40.50.5-0.50.60.5-0.50.5-0.50.5-0.50.5-0.50.5-2.5-3.6-0.6-0.6
Bone: post-yield work0.00.00.50.10.00.10.2-0.70.30.10.2-0.1-0.1-0.20.2-0.1-0.10.1-0.00.0-0.00.0-0.00.0-0.00.30.2-0.0-0.0
Progressive ratio test 1 active lever presses0.20.20.7-0.5-0.3-0.4-0.1-0.80.70.80.5-0.4-0.3-0.50.5-0.5-0.50.5-0.30.3-0.30.3-0.30.3-0.30.70.30.50.5
Progressive ratio test 1 breakpoint0.20.20.7-0.5-0.4-0.4-0.2-0.80.70.80.5-0.4-0.3-0.40.4-0.5-0.40.5-0.30.3-0.30.3-0.30.3-0.30.70.20.40.4
Progressive ratio test 1 inactive lever presses4.26.07.9-2.6-2.7-2.8-1.3-1.32.42.72.5-2.5-2.5-2.52.5-2.5-2.52.6-2.72.7-2.72.7-2.72.7-2.71.6-0.22.62.6
Progressive ratio test 2 active lever presses0.20.30.7-0.5-0.4-0.5-0.1-0.80.60.60.7-0.5-0.5-0.60.6-0.6-0.60.5-0.40.4-0.40.4-0.40.4-0.40.80.30.50.5
Progressive ratio test 2 breakpoint0.20.20.7-0.5-0.3-0.4-0.1-0.70.60.60.7-0.5-0.5-0.60.6-0.6-0.60.5-0.40.4-0.40.4-0.40.4-0.40.80.30.50.5
Progressive ratio test 2 inactive lever presses0.20.40.7-0.8-0.6-0.9-0.6-0.20.30.50.7-0.6-0.6-0.60.6-0.8-0.60.6-0.60.6-0.60.6-0.60.6-0.60.3-0.50.60.6
Incentive Sensitization - Responses0.00.00.1-0.1-0.3-0.1-0.20.30.10.10.2-0.2-0.2-0.10.1-0.2-0.10.10.0-0.00.0-0.00.0-0.00.00.30.10.00.0
Incentive Sensitization - Breakpoint0.00.00.1-0.1-0.2-0.1-0.20.30.10.10.3-0.2-0.2-0.10.1-0.2-0.10.10.0-0.00.0-0.00.0-0.00.00.30.10.00.0
Sum of active levers in priming session hrs 5-60.50.41.0-0.3-0.3-0.50.4-0.90.90.70.8-0.7-0.7-0.60.6-0.7-0.60.8-0.60.6-0.60.6-0.60.6-0.61.00.70.60.6
Progressive ratio0.40.71.61.21.31.11.1-0.9-0.4-0.5-0.90.80.90.8-0.80.50.8-0.80.7-0.70.7-0.70.7-0.70.70.10.7-0.8-0.8
Food seeking constrained by brief footshock0.20.20.60.50.50.60.30.8-0.4-0.4-0.60.70.70.5-0.50.30.4-0.40.4-0.40.4-0.40.4-0.40.4-0.30.2-0.4-0.4
Seeking ratio, punishment vs. effort0.20.31.3-0.6-0.6-0.5-0.21.10.30.40.6-0.5-0.5-0.60.6-0.4-0.60.7-0.50.5-0.50.5-0.50.5-0.50.10.10.60.6
Retroperitoneal fat weight4.318.426.0-4.8-5.1-4.9-2.5-1.44.44.84.5-4.5-4.5-4.54.5-4.8-4.54.6-4.54.5-4.54.5-4.54.5-4.52.9-0.74.44.4
Reaction time number correct3.87.313.0-1.0-1.0-2.01.5-2.73.33.23.1-3.0-3.1-2.82.8-2.9-2.82.8-2.72.7-2.72.7-2.72.7-2.73.62.32.72.7
Reaction time mean minus median0.30.71.40.40.40.7-0.40.9-1.1-1.1-1.00.90.90.9-0.91.20.9-0.90.8-0.80.8-0.80.8-0.80.8-1.1-0.7-0.9-0.9
Reaction time mean minus median AUC0.10.31.7-0.5-0.5-0.1-1.01.1-0.7-0.5-0.30.30.30.2-0.20.50.2-0.30.1-0.10.1-0.10.1-0.10.1-1.0-1.3-0.2-0.2
Reaction time num false alarms0.10.20.30.60.50.50.5-0.5-0.4-0.5-0.40.40.40.5-0.50.20.5-0.50.4-0.40.4-0.40.4-0.40.40.0-0.0-0.6-0.6
Reaction time num false alarms AUC0.20.30.60.80.80.60.8-0.5-0.5-0.6-0.40.50.50.5-0.50.30.5-0.60.4-0.40.4-0.40.4-0.40.40.00.2-0.6-0.6
Reaction time trials correct on left3.87.313.0-1.0-1.0-2.01.5-2.73.33.23.1-3.0-3.1-2.82.8-2.9-2.82.8-2.72.7-2.72.7-2.72.7-2.73.62.32.72.7
Reaction time trials on left4.07.513.2-1.0-1.0-2.11.5-2.73.43.23.2-3.1-3.1-2.92.9-3.0-2.92.9-2.82.8-2.82.8-2.82.8-2.83.62.32.82.8
Reaction time mean0.40.61.0-0.4-0.5-0.80.0-0.20.80.80.7-0.7-0.7-0.70.7-0.7-0.70.8-1.01.0-1.01.0-1.01.0-1.00.60.20.80.8
Reaction time mean AUC0.50.81.3-0.4-0.5-0.80.1-0.50.90.90.9-0.8-0.8-0.90.9-0.8-0.90.9-1.11.1-1.11.1-1.11.1-1.10.80.31.01.0
Median of all reaction times0.71.01.5-0.5-0.6-1.00.2-0.41.21.21.0-1.0-1.0-1.01.0-1.0-1.01.1-1.21.2-1.21.2-1.21.2-1.20.90.51.11.1
Reaction time omissions0.30.40.7-0.6-0.5-0.9-0.60.80.30.50.5-0.6-0.6-0.70.7-0.4-0.70.6-0.70.7-0.70.7-0.70.7-0.7-0.2-0.60.70.7
Reaction time false alarm rate2.23.14.51.21.31.7-0.00.9-2.1-2.1-2.02.02.01.9-1.91.82.0-2.01.8-1.81.8-1.81.8-1.81.8-1.8-1.0-2.0-2.0
Reaction time premature initiation rate0.40.62.61.41.30.91.6-1.0-0.5-0.8-0.50.60.60.5-0.50.60.5-0.50.5-0.50.5-0.50.5-0.50.50.41.3-0.5-0.5
Reaction time premature initiations1.22.16.40.70.6-0.42.4-2.51.51.11.4-1.2-1.3-1.31.3-1.2-1.21.2-1.21.2-1.21.2-1.21.2-1.22.42.51.21.2
Std. dev. reaction times0.00.10.60.50.60.30.80.2-0.3-0.3-0.10.10.1-0.00.00.30.0-0.1-0.10.1-0.10.1-0.10.1-0.10.00.50.00.0
Reaction time trials completed4.07.513.2-1.0-1.0-2.11.5-2.73.43.23.2-3.1-3.1-2.92.9-3.0-2.92.9-2.82.8-2.82.8-2.82.8-2.83.62.32.82.8
Reaction time trials AUC4.27.914.0-1.1-1.0-2.21.5-2.93.53.33.3-3.1-3.2-3.03.0-3.0-2.92.9-2.82.8-2.82.8-2.82.8-2.83.72.42.82.8
Run reversals in cocaine runway, females0.40.43.20.60.90.21.8-0.40.40.40.4-0.4-0.4-0.30.3-0.6-0.40.2-0.20.2-0.20.2-0.20.2-0.21.01.80.30.3
Run reversals in cocaine runway, males0.30.32.1-0.5-0.3-0.0-1.3-0.30.10.0-0.60.40.50.5-0.50.40.5-0.40.4-0.40.4-0.40.4-0.40.4-0.6-1.4-0.4-0.4
Latency to leave start box in cocaine runway0.60.71.91.21.41.11.2-0.7-0.2-0.7-0.60.60.70.8-0.80.70.8-0.70.8-0.80.8-0.80.8-0.80.80.40.9-0.7-0.7
Latency to leave start box in cocaine runway, F0.30.31.90.20.50.01.1-1.40.80.30.5-0.5-0.5-0.40.4-0.4-0.30.4-0.30.3-0.30.3-0.30.3-0.31.21.20.40.4
Latency to leave start box in cocaine runway, M1.51.42.11.51.31.40.60.1-0.7-0.9-1.21.11.31.3-1.31.31.3-1.21.3-1.31.3-1.31.3-1.31.3-0.50.1-1.3-1.3
Std. dev. time between licks in bursts2.63.54.6-0.9-1.6-1.60.2-1.41.91.82.0-2.0-1.9-2.02.0-2.0-2.02.1-2.12.1-2.12.1-2.12.1-2.12.00.52.12.1
Total sessions with >9 infusions0.20.30.80.60.90.80.70.1-0.10.0-0.40.50.60.4-0.40.40.4-0.30.5-0.50.5-0.50.5-0.50.50.20.8-0.5-0.5
Short access day 1 total inactive lever presses0.10.20.9-0.5-0.6-0.4-0.70.90.00.50.2-0.2-0.1-0.20.2-0.2-0.20.3-0.40.4-0.40.4-0.40.4-0.4-0.3-0.40.40.4
Short access day 10 total inactive lever presses2.25.39.7-2.7-3.1-3.0-1.9-0.51.72.02.3-2.3-2.4-2.32.3-2.3-2.32.3-2.52.5-2.52.5-2.52.5-2.50.8-1.02.42.4
Short access day 1 total infusions0.30.42.21.21.20.91.5-0.0-0.4-0.4-0.20.50.40.3-0.30.40.3-0.40.4-0.40.4-0.40.4-0.40.40.41.4-0.4-0.4
Short access day 10 total infusions0.30.41.4-1.2-1.2-0.7-1.2-0.70.80.80.4-0.4-0.4-0.50.5-0.5-0.50.6-0.40.4-0.40.4-0.40.4-0.40.3-0.80.40.4
Short access total infusions0.10.10.5-0.10.1-0.00.3-0.40.50.60.3-0.2-0.2-0.30.3-0.3-0.30.3-0.20.2-0.20.2-0.20.2-0.20.70.70.20.2
Short access day 1 locomotion0.70.81.20.80.91.10.40.4-0.8-0.8-0.91.01.01.0-1.00.91.0-0.91.0-1.01.0-1.01.0-1.01.0-0.50.1-1.1-1.1
Short access day 10 total locomotion0.61.21.80.60.51.0-0.30.5-1.3-1.2-1.31.31.31.2-1.21.21.2-1.11.1-1.11.1-1.11.1-1.11.1-1.0-0.8-1.1-1.1
Short access total locomotion0.91.11.50.60.61.1-0.30.9-1.0-0.9-1.21.21.21.2-1.21.11.2-1.01.2-1.21.2-1.21.2-1.21.2-0.9-0.6-1.2-1.2
One hour access (0.3 mA shock)0.50.51.5-0.3-0.2-0.40.4-1.20.90.80.8-0.7-0.7-0.70.7-0.8-0.70.8-0.60.6-0.60.6-0.60.6-0.61.20.90.60.6
Compulsive drug intake0.70.91.4-0.8-1.2-1.1-0.3-0.70.90.81.0-1.1-1.0-1.01.0-1.1-1.01.1-1.01.0-1.01.0-1.01.0-1.00.70.30.90.9
One hour access (shock baseline)0.00.10.1-0.10.20.3-0.3-0.2-0.00.0-0.20.30.30.3-0.30.20.3-0.30.4-0.40.4-0.40.4-0.40.40.1-0.3-0.3-0.3
Social response proportion0.40.40.7-0.20.0-0.40.7-0.30.40.40.7-0.7-0.7-0.70.7-0.7-0.70.7-0.80.8-0.80.8-0.80.8-0.80.50.90.80.8
Social responses0.50.71.0-0.8-0.6-0.70.1-0.30.70.81.0-0.9-1.0-0.90.9-0.9-0.90.8-0.90.9-0.90.9-0.90.9-0.90.50.40.90.9
Social time0.30.50.80.0-0.2-0.30.4-0.20.50.50.7-0.7-0.7-0.70.7-0.6-0.70.7-0.90.9-0.90.9-0.90.9-0.90.60.60.80.8
Soleus weight0.51.45.7-2.3-2.2-1.6-2.4-1.00.70.80.8-0.9-0.9-0.80.8-0.7-0.80.8-0.80.8-0.80.8-0.80.8-0.8-0.3-2.10.80.8
Bone: stiffness0.10.20.9-0.7-0.6-0.5-0.90.9-0.00.20.2-0.2-0.2-0.20.2-0.2-0.20.2-0.30.3-0.30.3-0.30.3-0.3-0.5-0.90.20.2
Tibialis anterior weight0.00.11.20.20.30.10.5-1.10.2-0.0-0.00.10.1-0.00.00.1-0.0-0.10.0-0.00.0-0.00.0-0.00.00.20.20.00.0
Time to tail flick, vehicle, before self-admin0.90.91.50.40.20.9-0.30.2-0.8-0.9-0.90.91.01.0-1.00.81.0-1.11.2-1.21.2-1.21.2-1.21.2-0.7-0.5-1.2-1.2
Time to tail flick, vehicle, after self-admin1.01.32.41.21.01.20.21.2-1.5-1.5-1.21.21.21.3-1.31.51.3-1.21.1-1.11.1-1.11.1-1.11.1-1.2-0.2-1.0-1.0
Time to tail flick, test, before self-admin0.40.51.20.70.60.80.40.3-1.1-1.0-0.70.70.70.7-0.70.80.7-0.70.6-0.60.6-0.60.6-0.60.6-0.6-0.2-0.6-0.6
Time to tail flick, test, after self-admin0.90.93.90.40.50.8-0.02.0-1.3-0.9-0.80.70.70.9-0.90.70.9-0.91.1-1.11.1-1.11.1-1.11.1-1.1-0.2-1.0-1.0
Delta time to tail flick, vehicle, before/after SA0.80.81.3-0.5-0.5-0.9-0.2-0.20.60.81.0-1.0-1.1-0.90.9-0.7-0.91.0-1.11.1-1.11.1-1.11.1-1.10.50.21.11.1
Delta time to tail flick, test, before/after SA0.40.52.90.50.70.60.21.7-0.6-0.5-0.50.50.50.6-0.60.40.6-0.60.7-0.70.7-0.70.7-0.70.7-0.70.2-0.6-0.6
Tibia length2.67.136.3-5.4-4.8-3.6-6.04.70.11.30.8-1.2-1.2-1.31.3-1.2-1.41.3-1.31.3-1.31.3-1.31.3-1.3-2.8-4.91.31.3
Ambulatory time before self-admin1.82.64.6-2.1-2.1-2.1-1.60.11.31.41.6-1.7-1.8-1.71.7-1.7-1.71.7-1.71.7-1.71.7-1.71.7-1.70.3-1.01.71.7
Ambulatory time after self-admin2.42.83.7-1.3-1.3-1.70.0-1.51.91.71.8-1.9-1.8-1.81.8-1.8-1.81.9-1.81.8-1.81.8-1.81.8-1.81.70.81.71.7
Bone: tissue strength2.92.94.7-2.0-1.9-1.9-1.0-2.21.71.71.9-1.7-1.7-1.91.9-1.7-1.81.7-1.71.7-1.71.7-1.71.7-1.71.2-0.31.71.7
Total heroin consumption0.20.30.8-0.4-0.1-0.5-0.30.90.30.50.4-0.5-0.5-0.60.6-0.2-0.60.6-0.60.6-0.60.6-0.60.6-0.6-0.1-0.00.60.6
Bone: trabecular number0.40.60.90.40.60.70.1-0.2-0.6-0.8-0.90.80.90.9-0.90.70.9-0.91.0-1.01.0-1.01.0-1.01.0-0.5-0.1-0.9-0.9
Bone: trabecular spacing5.16.89.0-1.2-1.3-2.10.8-0.92.72.93.0-3.0-3.0-2.92.9-2.9-2.92.9-2.92.9-2.92.9-2.92.9-2.92.51.92.82.8
Bone: trabecular thickness1.41.73.4-0.10.00.6-1.2-0.6-1.1-1.3-1.41.31.41.4-1.41.31.4-1.41.4-1.41.4-1.41.4-1.41.4-1.2-1.8-1.5-1.5
Bone: trabecular tissue density0.60.91.71.01.01.00.51.3-1.0-0.9-1.00.90.91.0-1.00.91.0-0.90.9-0.90.9-0.90.9-0.90.9-0.80.1-1.0-1.0
Water consumed over 24 hours0.30.40.60.00.10.5-0.6-0.2-0.6-0.7-0.80.80.80.8-0.80.80.8-0.80.7-0.70.7-0.70.7-0.70.7-0.6-0.4-0.7-0.7
Number of responses in last shaping day0.20.20.30.1-0.00.3-0.50.3-0.4-0.2-0.30.50.40.5-0.50.50.5-0.40.5-0.50.5-0.50.5-0.50.5-0.5-0.6-0.5-0.5