Hub : Genes

Sgsh

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Sgsh 0.1 0.06 1.2e-03 0.1 0.06 0.05 0.08 5.4e-05 1.1e-03 2.3e-03 1.8e-04
2 Adipose gene expression Sgsh 0.19 0.09 0.0e+00 0.2 0.2 0.2 0.2 4.2e-22 1.5e-21 1.1e-21 7.0e-22
3 Brain gene expression Sgsh 0.28 0.12 0.0e+00 0.25 0.25 0.25 0.25 6.8e-23 5.0e-23 2.1e-23 1.8e-23
4 NAcc gene expression Sgsh 0.14 0.07 5.0e-11 0.09 0.08 0.08 0.08 4.9e-10 1.2e-09 6.2e-10 3.7e-09
5 IL gene expression Sgsh 0.37 0.15 3.5e-06 0.12 0.14 0.06 0.13 1.1e-03 2.7e-04 1.6e-02 4.4e-04
6 BLA gene expression Sgsh 0.39 0.19 1.7e-12 0.2 0.19 0.22 0.17 8.0e-11 2.2e-10 3.7e-12 1.8e-09
7 PL gene expression Sgsh 0.34 0.13 0.0e+00 0.3 0.37 0.36 0.32 1.5e-33 1.6e-42 1.7e-41 7.0e-36
8 Brain intron excision ratio chr10_104606961_104607246 0.03 0.02 2.5e-03 0.02 0.02 0 0.01 4.3e-03 3.3e-03 1.4e-01 2.3e-02
9 pVTA isoform ratio XM_039087539.1 0.1 0.06 2.6e-04 0.04 0.06 0.03 0.04 4.9e-03 1.1e-03 1.9e-02 6.9e-03
10 LHb gene expression Sgsh 0.21 0.13 4.3e-03 0.04 0 -0.01 0 4.2e-02 2.8e-01 5.5e-01 3.2e-01
11 BLA intron excision ratio chr10_104606961_104607246 0.12 0.07 1.4e-05 0.09 0.09 0.09 0.09 1.4e-05 2.6e-05 2.3e-05 1.1e-05
12 pVTA isoform ratio XM_039087537.1 0.12 0.07 6.6e-05 0.08 0.08 0.05 0.06 2.1e-04 2.2e-04 2.6e-03 9.0e-04
13 pVTA intron excision ratio chr10_104605697_104607246 0.09 0.06 4.2e-04 0.09 0.08 0.09 0.09 1.3e-04 2.2e-04 1.1e-04 9.8e-05
14 Liver isoform ratio XM_039087537.1 0.05 0.03 7.4e-05 0.02 0.02 0.03 0.02 3.3e-03 1.2e-03 8.3e-04 1.7e-03
15 PL isoform ratio XM_039087539.1 0.06 0.04 4.6e-06 0.06 0.05 0.05 0.06 6.4e-07 4.0e-06 3.3e-06 4.5e-07
16 PL isoform ratio XM_039087537.1 0.04 0.03 2.6e-03 0.03 0.02 0.02 0.03 3.3e-04 3.4e-03 2.0e-03 7.3e-04
17 Adipose intron excision ratio chr10_104606961_104607246 0.04 0.03 1.9e-04 0.03 0.02 0.03 0.03 1.5e-04 3.8e-03 6.9e-04 7.1e-04
18 Brain intron excision ratio chr10_104605697_104607246 0.06 0.04 1.7e-05 0.06 0.05 0.06 0.05 3.1e-06 2.3e-05 6.8e-06 9.0e-06
19 PL intron excision ratio chr10_104605697_104607246 0.06 0.03 2.7e-07 0.06 0.04 0.04 0.05 5.1e-07 4.7e-05 3.2e-05 8.0e-06
20 BLA intron excision ratio chr10_104605697_104607246 0.24 0.15 1.4e-05 0.11 0.11 0.11 0.1 1.4e-06 1.9e-06 2.0e-06 8.3e-06
21 OFC gene expression Sgsh 0.33 0.14 5.1e-06 0.24 0.13 0.23 0.23 2.5e-06 5.1e-04 3.5e-06 2.8e-06
22 Brain isoform ratio XM_039087537.1 0.03 0.03 3.8e-03 0.03 0.02 0.02 0.02 1.3e-03 3.9e-03 9.7e-03 3.4e-03
23 Brain isoform ratio XM_039087539.1 0.03 0.03 2.9e-03 0.03 0.03 0.04 0.03 4.2e-04 1.0e-03 1.7e-04 7.6e-04
24 Liver gene expression Sgsh 0.27 0.13 0.0e+00 0.11 0.16 0.16 0.16 1.8e-12 8.9e-18 2.1e-17 2.5e-17

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.10.20.60.20.2-0.2-0.0-0.60.3-0.20.7-0.80.60.4-0.4-0.40.1-0.4-0.4-0.30.40.40.40.4-0.40.40.3
Area under the delay curve1.11.12.8-1.5-1.71.1-1.71.6-1.10.9-1.41.5-1.3-1.21.00.90.20.80.70.8-0.8-0.6-0.8-0.70.7-0.2-0.4
BMI with tail1.13.75.41.41.3-1.41.1-2.12.0-2.02.1-2.02.02.1-2.3-2.2-1.6-2.2-2.3-2.32.22.22.21.8-1.81.61.5
BMI without tail7.515.419.23.43.4-3.23.1-4.34.2-4.14.2-3.94.14.2-4.4-4.2-3.4-4.2-4.3-4.34.24.24.23.9-3.93.42.8
Body weight3.112.823.74.94.7-4.94.0-3.94.6-4.52.3-1.62.83.1-3.4-3.5-4.4-3.4-3.5-3.43.43.43.32.9-2.93.30.2
Weight adjusted by age2.02.35.12.12.2-1.82.3-1.71.8-1.80.9-0.61.41.3-1.3-1.3-1.8-1.3-1.3-1.21.11.41.21.2-1.21.5-0.3
Bone surface0.10.10.30.40.4-0.30.40.2-0.0-0.0-0.50.6-0.3-0.40.30.3-0.20.40.40.4-0.3-0.4-0.3-0.40.4-0.2-0.5
Bone volume0.00.10.20.40.4-0.40.3-0.40.3-0.30.3-0.30.30.2-0.2-0.2-0.2-0.2-0.2-0.10.20.20.20.2-0.20.10.1
Breakpoint value in progressive ratio session1.01.11.60.90.9-1.00.9-1.31.1-1.01.2-1.21.11.2-1.1-1.0-0.7-1.1-1.1-1.11.11.01.21.0-1.00.80.7
Number of licking bursts0.10.10.30.50.5-0.50.2-0.40.5-0.50.2-0.10.30.4-0.4-0.4-0.5-0.5-0.4-0.40.40.40.40.1-0.10.20.1
Context. condit. distance diff. score2.32.74.60.70.7-0.70.9-1.31.4-1.71.7-1.62.02.0-1.9-1.9-1.5-1.9-1.9-1.91.91.91.91.7-1.71.52.1
Locomotion velocity, session 15.76.18.1-2.1-2.02.2-1.82.8-2.62.5-2.82.6-2.5-2.62.62.72.12.62.62.7-2.6-2.7-2.6-2.72.7-2.1-1.5
Locomotion distance, session 10.60.83.0-1.7-1.71.6-1.60.8-1.11.10.0-0.3-0.3-0.30.30.41.40.40.30.4-0.4-0.4-0.4-0.80.8-0.90.7
Locomotion velocity, session 24.65.37.7-2.6-2.72.7-2.52.5-2.72.8-1.81.4-2.4-2.32.32.32.82.32.32.3-2.3-2.3-2.3-2.12.1-2.1-0.9
Locomotion distance, session 20.20.21.4-0.6-0.60.6-0.4-0.4-0.20.40.9-1.20.40.3-0.3-0.31.0-0.3-0.3-0.30.30.30.30.1-0.1-0.10.6
Locomotion velocity, session 32.02.33.2-1.6-1.51.5-0.91.8-1.61.5-1.61.5-1.3-1.51.51.61.51.61.61.5-1.6-1.6-1.6-1.71.7-1.5-0.6
Locomotion distance, session 32.22.45.2-2.3-2.22.2-2.01.7-1.91.8-1.00.7-1.0-1.21.21.31.91.31.31.3-1.3-1.3-1.3-1.51.5-1.50.1
Stereotopy head waving bouts, day 30.40.50.9-0.6-0.70.6-0.51.0-0.70.6-0.90.9-0.8-0.90.70.70.40.70.70.8-0.8-0.8-0.8-0.50.5-0.5-0.3
Stereotopy head waving duration, day 30.10.10.4-0.4-0.50.3-0.00.6-0.30.2-0.50.5-0.2-0.40.30.2-0.00.30.30.3-0.3-0.3-0.3-0.10.1-0.10.2
Locomotion velocity, session 70.40.41.3-1.1-1.01.1-0.80.9-0.90.6-0.50.4-0.1-0.20.50.40.50.40.30.4-0.4-0.4-0.4-0.60.6-0.80.7
Locomotion distance, session 70.91.15.3-2.0-2.02.0-1.90.7-1.00.80.6-1.00.10.4-0.2-0.21.0-0.2-0.2-0.20.20.20.20.1-0.1-0.62.3
Stereotopy head waving bouts, day 70.50.61.20.50.6-0.70.5-0.50.8-1.00.3-0.11.10.7-0.7-0.8-1.1-0.8-0.8-0.80.80.80.80.8-0.80.90.6
Stereotopy head waving duration, day 70.30.41.31.01.0-1.11.1-0.30.8-0.9-0.20.50.80.3-0.3-0.4-1.1-0.4-0.4-0.30.40.40.40.3-0.30.7-0.3
Locomotion velocity, session 80.40.52.5-0.5-0.50.4-0.50.10.2-0.50.3-0.30.80.8-0.9-0.8-0.9-0.8-0.8-0.80.80.80.80.7-0.70.61.6
Locomotion distance, session 82.94.37.90.40.5-0.50.7-1.91.5-1.62.7-2.82.52.5-2.5-2.4-0.9-2.5-2.4-2.42.42.42.42.0-2.01.62.8
Degree of sensitization distance2.22.23.21.00.9-0.91.0-1.51.3-1.31.8-1.81.31.6-1.5-1.6-1.1-1.7-1.6-1.61.61.61.61.7-1.71.11.5
Degree of sensitization stereotypy1.01.12.30.91.0-1.00.6-1.01.2-1.30.8-0.61.51.2-1.1-1.1-1.2-1.2-1.1-1.11.21.21.21.0-1.01.10.7
Conditioned locomotion5.26.17.72.52.4-2.62.3-2.82.8-2.62.4-2.12.52.4-2.5-2.6-2.5-2.6-2.6-2.62.52.62.62.5-2.52.31.0
Cocaine response after cond. corrected0.10.10.4-0.4-0.30.4-0.00.3-0.30.2-0.20.2-0.1-0.10.20.30.20.30.30.2-0.2-0.2-0.2-0.60.6-0.70.2
Cocaine response after cond. not corrected0.80.91.9-1.0-0.91.0-0.51.1-1.00.9-0.80.8-0.6-0.70.91.00.91.01.00.9-0.9-0.9-0.9-1.21.2-1.40.0
Cocaine response before conditioning0.81.01.4-1.1-1.11.1-1.01.2-1.21.0-0.90.8-0.8-0.91.00.90.91.01.01.0-1.0-1.0-1.0-1.01.0-1.1-0.1
Saline control response1.31.74.62.12.1-2.11.8-1.41.6-1.70.6-0.31.31.1-1.0-1.1-1.4-1.0-1.1-1.01.01.01.00.8-0.81.3-0.2
Bone: connectivity density0.00.10.2-0.3-0.20.3-0.3-0.1-0.10.10.4-0.50.30.2-0.2-0.20.0-0.2-0.2-0.10.20.20.20.2-0.20.20.4
Bone: cortical apparent density1.62.14.6-2.1-2.22.0-1.91.4-1.81.9-0.60.2-1.1-1.21.21.22.01.21.21.2-1.2-1.2-1.2-1.31.3-1.6-0.1
Bone: cortical area2.94.413.53.43.3-3.33.7-2.32.6-2.50.8-0.31.71.3-1.4-1.4-2.9-1.5-1.4-1.41.41.41.41.5-1.52.3-1.2
Bone: cortical porosity0.80.92.40.70.6-0.70.60.6-0.20.2-1.31.4-1.1-1.11.01.10.31.01.01.1-1.0-1.0-1.1-0.90.9-0.7-1.5
Bone: cortical porosity0.40.41.20.90.8-0.90.90.20.2-0.3-0.91.1-0.6-0.60.50.5-0.30.50.50.6-0.5-0.5-0.5-0.40.4-0.1-1.1
Bone: cortical thickness2.23.613.03.23.2-3.23.6-2.32.4-2.00.8-0.31.31.0-1.1-1.1-2.2-1.2-1.1-1.11.11.11.11.1-1.11.9-1.8
Bone: cortical thickness1.11.22.71.61.6-1.61.5-1.31.4-1.20.6-0.40.80.8-0.9-0.9-1.6-0.9-0.9-0.90.90.90.90.8-0.81.4-0.7
Bone: cortical tissue density1.92.55.3-2.2-2.32.2-2.11.5-1.92.1-0.70.3-1.2-1.31.31.32.21.31.31.3-1.3-1.3-1.4-1.41.4-1.7-0.1
Condit. Reinf. active minus inactive responses2.12.33.71.81.6-1.81.9-1.91.8-1.61.4-1.31.41.4-1.5-1.4-1.6-1.4-1.4-1.51.41.51.41.6-1.61.60.1
Condit. Reinf. active-inactive response ratio1.71.82.61.21.1-1.21.2-1.51.4-1.31.4-1.31.31.3-1.4-1.3-1.5-1.4-1.4-1.41.41.41.41.6-1.61.50.5
Condit. Reinf. active responses2.93.65.92.42.3-2.42.4-2.42.3-2.01.7-1.51.81.7-1.7-1.7-1.8-1.7-1.7-1.71.71.71.71.8-1.81.9-0.1
Condit. Reinf. inactive responses0.50.61.41.11.2-1.11.0-1.10.9-0.80.8-0.70.80.7-0.6-0.7-0.4-0.7-0.6-0.60.60.60.60.5-0.50.6-0.2
Incentive salience index mean1.51.83.21.71.6-1.71.8-1.71.6-1.41.2-1.01.21.2-1.2-1.2-1.4-1.2-1.2-1.21.21.21.21.3-1.31.4-0.1
Condit. Reinf. lever presses0.20.20.40.30.4-0.30.4-0.60.4-0.40.6-0.60.60.5-0.5-0.5-0.3-0.5-0.4-0.50.50.50.50.6-0.60.50.2
Condit. Reinf. active minus inactive responses1.01.32.81.31.3-1.31.6-1.01.3-1.30.5-0.21.20.9-1.0-1.1-1.6-1.1-1.0-1.01.01.01.01.1-1.11.7-0.1
Condit. Reinf. active-inactive response ratio1.11.23.21.81.8-1.71.7-1.11.4-1.30.30.00.70.6-0.8-0.8-1.3-0.7-0.7-0.80.80.80.80.7-0.71.3-0.8
Condit. Reinf. active responses1.01.42.80.70.7-0.80.9-1.11.1-1.11.1-1.01.41.3-1.3-1.3-1.1-1.3-1.3-1.31.31.31.31.5-1.51.70.7
Condit. Reinf. inactive responses0.30.31.2-0.8-0.70.6-0.4-0.2-0.20.10.8-0.90.60.6-0.5-0.50.2-0.5-0.5-0.50.50.50.50.7-0.70.31.1
Condit. Reinf. lever presses2.12.84.30.70.7-0.70.4-1.71.4-1.32.0-2.12.01.9-1.9-1.8-1.0-1.8-1.8-1.91.91.91.92.1-2.11.81.7
Condit. Reinf. lever reinforcers received1.82.54.20.70.6-0.80.9-1.51.3-1.41.6-1.61.91.8-1.8-1.8-1.3-1.8-1.7-1.81.81.81.82.0-2.02.01.3
Conditioned reinforcement - actives0.30.30.80.70.9-0.40.9-0.80.5-0.50.7-0.70.80.7-0.5-0.3-0.0-0.2-0.2-0.50.40.10.50.3-0.3-0.20.3
Conditioned reinforcement - inactives0.91.02.61.61.4-1.41.4-1.11.3-1.20.6-0.40.80.8-1.0-1.0-1.2-0.9-0.8-0.90.80.60.90.9-0.90.6-0.1
Conditioned locomotion0.30.41.51.21.2-0.81.2-0.90.7-0.60.6-0.60.70.6-0.6-0.20.0-0.1-0.1-0.40.30.00.40.1-0.1-0.4-0.2
Patch foraging indifference point 0 sec0.71.22.71.00.7-0.90.6-1.41.2-0.81.6-1.71.00.9-1.3-1.2-0.3-1.1-1.0-1.31.01.11.11.3-1.30.80.6
Patch foraging indifference point AUC0.10.20.40.1-0.0-0.3-0.3-0.30.5-0.30.5-0.50.40.3-0.6-0.3-0.2-0.3-0.4-0.60.60.40.30.5-0.50.40.4
Delay disc. indifference point, 0s delay0.10.10.70.00.2-0.20.20.4-0.1-0.2-0.60.8-0.0-0.00.20.1-0.60.30.20.3-0.00.0-0.1-0.20.20.1-0.2
Delay disc. indifference point, 16s delay0.40.41.9-1.2-1.40.7-1.30.3-0.30.30.3-0.4-0.10.00.1-0.4-0.0-0.5-0.4-0.20.30.40.20.6-0.60.60.9
Delay disc. indifference point, 2s delay0.30.31.3-0.6-0.60.2-0.60.8-0.30.2-1.01.1-0.7-0.60.40.4-0.40.40.30.3-0.4-0.2-0.4-0.30.30.3-0.7
Delay disc. indifference point, 24s delay4.24.17.4-2.7-2.72.3-2.72.3-2.32.2-1.81.6-2.4-2.22.21.81.91.71.62.0-1.8-1.7-1.8-1.71.7-1.6-0.8
Delay disc. indifference point, 4s delay0.20.21.1-0.5-0.70.1-0.70.8-0.1-0.0-0.91.1-0.6-0.40.20.3-0.60.30.1-0.0-0.10.0-0.1-0.10.10.5-0.2
Delay disc. indifference point, 8s delay2.12.15.6-1.3-1.41.2-1.42.0-1.41.1-2.22.4-1.7-1.61.51.50.31.41.31.5-1.4-1.3-1.4-1.31.3-0.6-1.1
Indifference point function ln k0.40.51.7-1.2-1.11.3-0.90.6-1.00.9-0.0-0.3-0.5-0.30.40.41.20.40.40.4-0.5-0.4-0.4-0.50.5-0.90.5
Indifference point function log k0.40.51.7-1.2-1.11.3-0.90.6-1.00.9-0.0-0.3-0.5-0.30.40.41.20.40.40.4-0.5-0.4-0.4-0.50.5-0.90.5
Patch foraging total patch changes 0 sec1.21.94.41.00.7-0.90.6-1.71.4-1.02.0-2.11.31.2-1.6-1.5-0.4-1.5-1.4-1.61.41.51.41.6-1.61.01.0
Patch foraging total patch changes 12 sec0.50.61.80.60.1-0.8-0.1-1.11.0-0.51.2-1.30.60.3-0.8-0.70.2-0.7-0.7-1.00.90.90.81.0-1.00.60.2
Patch foraging total patch changes 18 sec1.62.04.20.2-0.1-0.5-0.1-1.31.3-1.01.9-2.11.31.3-1.7-1.6-0.6-1.6-1.7-1.91.81.71.51.7-1.71.41.7
Patch foraging total patch changes 24 sec2.02.43.51.71.3-1.51.2-1.71.9-1.61.5-1.31.61.4-1.6-1.5-1.5-1.6-1.6-1.81.61.61.51.7-1.71.70.6
Patch foraging total patch changes 6 sec0.30.51.51.10.9-1.20.6-1.21.1-0.50.9-1.00.40.2-0.6-0.30.1-0.3-0.4-0.70.50.40.50.5-0.50.3-0.5
Patch foraging time to switch 0 sec1.01.52.3-1.2-1.31.1-1.31.5-1.41.2-1.31.2-1.5-1.31.41.21.11.21.31.3-1.3-1.3-1.2-1.11.1-0.7-0.7
Patch foraging water rate 0 sec5.58.810.62.82.7-2.72.6-3.23.2-3.12.9-2.73.23.0-3.2-3.2-3.0-3.2-3.2-3.13.13.23.03.1-3.12.81.7
Patch foraging water rate 12 sec1.92.95.50.70.8-0.41.1-1.71.3-1.32.3-2.42.02.1-1.9-2.1-0.9-2.1-2.0-1.71.91.91.71.7-1.71.02.2
Patch foraging water rate 18 sec3.04.06.81.61.7-1.41.8-2.32.0-2.02.4-2.32.62.5-2.2-2.1-1.4-2.1-2.1-2.12.22.12.21.6-1.60.92.0
Patch foraging water rate 24 sec9.212.817.52.32.4-2.52.6-3.83.5-3.54.2-4.13.93.9-3.8-4.1-2.6-4.1-4.1-3.94.04.03.93.6-3.62.93.3
Patch foraging water rate 6 sec0.81.22.30.80.8-0.41.0-1.21.0-1.11.4-1.41.41.5-1.4-1.1-0.6-1.1-1.2-1.21.21.11.20.6-0.60.21.3
Seeking ratio, delayed vs. immediate footshock0.40.41.61.11.3-0.81.2-0.70.6-0.60.00.20.40.4-0.4-0.3-0.8-0.2-0.1-0.2-0.00.20.20.3-0.31.0-1.0
Distance traveled before self-admin0.50.52.01.01.0-1.01.0-0.50.8-0.9-0.00.30.50.6-0.4-0.7-1.4-0.6-0.6-0.60.40.50.50.6-0.61.1-0.3
Distance traveled after self-admin1.61.73.40.71.1-0.71.1-1.51.1-1.11.8-1.81.71.8-1.3-1.3-0.7-1.3-1.3-1.41.21.21.41.3-1.31.11.4
Extensor digitorum longus weight0.93.67.80.30.2-0.4-0.1-1.91.4-1.32.6-2.82.12.3-2.2-2.2-0.6-2.1-2.2-2.22.22.22.22.2-2.21.52.3
Bone: elastic displacement1.21.33.11.51.6-1.51.8-1.61.4-1.11.2-1.11.41.0-1.0-0.9-0.7-1.0-1.0-0.91.00.91.00.8-0.80.9-0.4
Bone: elastic work2.53.210.43.23.2-3.23.0-2.22.4-2.00.9-0.51.51.0-1.1-1.0-1.8-1.1-1.1-1.11.11.01.11.0-1.01.6-1.6
Bone: endosteal estimation0.20.41.60.0-0.10.1-0.5-0.30.4-0.50.6-0.60.60.7-0.7-0.7-0.7-0.7-0.7-0.70.70.70.70.9-0.90.81.3
Bone: endosteal perimeter0.20.41.61.11.1-1.00.9-0.10.6-0.7-0.50.8-0.1-0.00.0-0.0-1.20.00.00.0-0.0-0.0-0.00.1-0.10.6-0.6
Epididymis fat weight1.74.15.32.12.0-2.01.9-2.22.3-2.31.9-1.61.92.1-2.0-2.2-2.1-2.3-2.3-2.12.12.12.21.8-1.81.61.1
Delta time in closed arm before/after self-admin0.20.20.70.60.2-0.10.20.20.0-0.0-0.60.7-0.3-0.30.40.4-0.10.50.40.2-0.4-0.4-0.2-0.40.4-0.0-0.8
Delta time in open arm before/after self-admin1.21.12.20.60.5-0.80.5-1.11.1-0.91.3-1.31.01.0-1.5-1.0-0.6-1.0-1.0-1.31.21.01.21.2-1.21.20.9
Diff in mean of infusions in LGA sessions0.00.10.20.1-0.2-0.1-0.2-0.10.2-0.20.2-0.2-0.00.1-0.5-0.2-0.2-0.3-0.3-0.20.30.20.30.3-0.30.40.1
Delay discount exponential model param1.61.74.11.82.0-1.32.0-1.91.3-1.11.7-1.71.61.5-1.3-1.1-0.4-1.0-0.9-1.01.00.91.00.9-0.90.30.6
Extinction: sum of active levers before priming0.50.51.3-1.1-1.11.0-1.10.6-0.90.8-0.1-0.1-0.2-0.20.20.71.00.70.60.4-0.4-0.6-0.5-0.50.5-0.70.5
Active lever presses in extinction session 60.60.61.00.50.4-0.60.4-0.70.8-0.70.7-0.60.60.7-0.7-0.9-0.9-0.9-0.9-0.80.80.70.80.9-0.91.00.3
Bone: final force3.04.811.33.33.3-3.43.2-2.42.8-2.71.1-0.61.81.7-1.8-1.8-2.8-1.8-1.8-1.81.81.81.81.5-1.52.4-0.6
Bone: final moment3.45.513.13.53.6-3.63.4-2.63.0-2.91.3-0.71.91.8-1.9-1.9-2.9-1.9-1.9-1.91.91.91.91.7-1.72.5-0.6
Food consumed during 24 hour testing period1.72.12.91.31.3-1.21.5-1.41.4-1.61.3-1.11.71.5-1.5-1.5-1.7-1.6-1.6-1.41.51.51.51.5-1.51.31.1
Glucose4.26.48.7-2.5-2.62.4-1.82.6-2.72.8-2.21.8-2.5-2.72.72.62.92.72.62.6-2.6-2.7-2.6-2.62.6-2.7-1.3
Heart weight0.30.40.90.80.8-0.91.0-0.90.9-0.70.7-0.70.70.6-0.4-0.7-0.4-0.6-0.6-0.60.60.50.70.5-0.50.30.2
Delay discount hyperbolic model param1.41.43.71.61.9-1.21.9-1.71.1-1.01.6-1.61.51.4-1.1-1.0-0.3-1.0-0.8-0.90.90.80.90.8-0.80.20.6
Intermittent access intake day 1-15 change0.10.10.50.20.3-0.20.3-0.10.3-0.4-0.10.20.20.2-0.2-0.3-0.7-0.4-0.5-0.20.20.20.20.3-0.30.20.1
Intermittent access intake escalation0.20.20.70.30.5-0.40.5-0.30.5-0.60.2-0.10.40.4-0.4-0.5-0.8-0.5-0.5-0.40.40.40.40.5-0.50.50.2
Intermittent access intake escalation 20.10.10.50.60.7-0.60.7-0.30.5-0.5-0.20.30.10.2-0.2-0.2-0.7-0.2-0.2-0.10.00.10.20.1-0.10.2-0.4
Intermitt. access day 1 inactive lever presses1.21.33.11.81.6-1.61.6-1.21.5-1.50.6-0.41.00.9-1.1-1.0-1.6-1.0-1.0-1.00.90.91.01.0-1.00.8-0.1
Intermitt. access day 15 inactive lever presses2.22.43.11.61.7-1.41.7-1.81.7-1.61.5-1.41.71.7-1.6-1.5-1.5-1.5-1.4-1.61.51.41.61.5-1.51.40.8
Intermitt. access escalation Index1.41.32.01.31.4-1.41.4-1.31.3-1.30.9-0.71.11.0-1.0-1.2-1.3-1.2-1.1-1.01.11.21.01.0-1.01.00.2
Intermittent access day 1 total infusions0.20.20.60.80.7-0.50.7-0.70.5-0.40.6-0.60.50.4-0.4-0.30.0-0.1-0.1-0.40.30.10.40.2-0.20.20.0
Intermittent access day 15 total infusions0.50.51.00.91.0-0.91.0-0.90.9-0.80.6-0.50.70.6-0.7-0.7-0.8-0.6-0.6-0.70.60.50.70.6-0.60.60.1
Intermittent access terminal intake (last 3 days)0.40.51.61.11.3-1.01.3-0.90.9-0.80.4-0.30.70.6-0.6-0.5-0.7-0.4-0.4-0.60.50.30.60.4-0.40.5-0.2
Intermittent access total infusions0.40.41.11.01.0-0.81.0-0.90.8-0.70.6-0.60.80.6-0.7-0.6-0.4-0.4-0.4-0.60.50.30.60.5-0.50.40.0
Intermittent access day 1 locomotion0.60.71.31.11.0-1.01.0-1.11.0-0.81.0-0.90.80.7-0.9-0.8-0.4-0.6-0.5-0.80.70.50.90.7-0.70.40.1
Intermittent access day 15 total locomotion0.10.10.60.80.8-0.60.8-0.40.5-0.40.10.00.20.2-0.2-0.1-0.3-0.00.1-0.20.1-0.10.20.0-0.00.1-0.5
Intermittent access total locomotion0.50.61.21.11.1-1.01.1-1.11.0-0.90.8-0.70.70.6-0.8-0.6-0.5-0.6-0.5-0.80.70.50.80.6-0.60.20.1
Intermittent access standard deviation0.40.41.6-0.6-0.50.5-0.51.0-0.60.4-1.21.3-0.6-0.70.50.7-0.20.70.60.6-0.7-0.7-0.5-0.50.5-0.3-0.5
Left kidney weight0.30.84.10.60.5-0.90.50.70.0-0.2-1.72.0-1.0-0.90.90.7-0.70.80.70.8-0.7-0.8-0.8-0.60.60.1-1.6
Right kidney weight0.10.31.60.50.5-1.00.30.20.5-0.4-0.91.3-0.7-0.60.40.1-0.90.10.00.1-0.0-0.1-0.2-0.40.40.4-1.2
Cocaine induced anxiety2.73.17.62.82.4-2.52.4-1.82.3-2.30.8-0.31.31.3-1.5-1.5-2.3-1.6-1.7-1.51.61.71.61.4-1.41.3-0.5
Post-drug Anxiety1.71.93.01.00.7-1.50.7-1.21.7-1.60.9-0.70.60.9-1.4-1.7-1.7-1.7-1.7-1.61.61.71.61.5-1.51.50.6
Baseline Anxiety3.43.610.9-3.3-3.12.7-3.12.2-2.32.2-1.10.7-1.8-1.61.61.52.11.41.61.4-1.5-1.5-1.5-1.31.3-1.20.6
Tail length4.312.924.24.84.9-4.84.4-4.14.5-4.42.7-2.03.13.2-3.4-3.2-4.0-3.2-3.3-3.43.33.23.43.1-3.13.20.4
Length with tail1.34.615.63.83.8-3.93.1-2.02.9-2.90.20.60.91.1-1.3-1.4-3.2-1.3-1.3-1.31.41.31.31.3-1.32.0-1.5
Length without tail1.22.68.20.0-0.1-0.3-0.21.6-0.80.8-2.62.9-2.0-2.01.91.50.01.61.61.8-1.6-1.6-1.8-1.61.6-0.7-2.5
Times rat made contact with spout0.50.62.21.41.5-1.21.5-1.00.9-0.80.5-0.41.00.5-0.4-0.4-0.4-0.3-0.4-0.40.40.40.40.2-0.2-0.0-0.5
Lifetime Intake0.10.10.40.50.6-0.30.6-0.40.3-0.30.2-0.20.40.3-0.3-0.1-0.10.0-0.0-0.20.1-0.10.20.1-0.10.0-0.1
Liver weight, left0.71.13.1-0.2-0.30.30.21.2-0.80.6-1.61.7-0.9-1.11.31.20.31.21.21.2-1.2-1.2-1.2-1.31.3-0.6-1.0
Liver weight, right0.91.55.72.42.2-2.42.2-1.01.4-1.3-0.30.80.20.1-0.2-0.4-1.6-0.4-0.5-0.30.30.40.30.5-0.51.5-1.9
Locomotor activity0.20.30.8-0.8-0.80.9-0.70.7-0.60.6-0.30.2-0.3-0.30.10.50.90.60.60.2-0.4-0.5-0.5-0.70.7-0.70.4
Locomotor testing distance0.10.10.6-0.5-0.50.7-0.50.3-0.30.20.1-0.20.20.1-0.3-0.00.30.00.1-0.20.00.0-0.1-0.30.3-0.40.7
Locomotor testing rearing0.91.42.40.50.3-0.40.5-1.11.0-1.01.5-1.61.31.3-1.5-1.5-0.6-1.5-1.4-1.51.31.41.31.0-1.01.01.5
Locomotion in novel chamber0.20.30.60.40.0-0.50.1-0.60.6-0.50.7-0.70.40.5-0.6-0.5-0.2-0.5-0.6-0.80.60.60.80.6-0.60.40.7
Locomotion in novel chamber post-restriction0.20.21.00.91.0-0.91.0-0.60.6-0.50.3-0.20.30.2-0.3-0.1-0.1-0.2-0.1-0.20.10.10.10.1-0.1-0.2-0.3
Fecal boli incidents, locomotor time 10.30.41.3-0.6-0.41.1-0.40.4-0.90.9-0.0-0.2-0.3-0.40.40.31.00.30.30.9-0.6-0.6-0.5-0.40.4-1.00.1
Change in fecal boli incidents, locomotor task3.23.05.8-2.1-2.41.9-2.31.9-1.92.0-1.31.0-2.0-1.81.61.72.01.71.71.5-1.6-1.6-1.6-1.61.6-1.5-0.4
Time >=10cm from walls, locomotor time 10.70.71.80.20.10.10.1-0.50.4-0.60.8-0.91.11.1-0.9-0.9-0.8-0.9-0.9-0.90.80.80.81.0-1.00.81.4
Bouts of movement, locomotor time 11.51.73.4-1.4-1.71.8-1.61.3-1.51.6-0.70.4-1.2-1.10.91.31.81.31.31.1-1.2-1.2-1.1-1.21.2-1.6-0.0
Total resting periods, locomotor time 12.32.64.9-1.6-1.92.1-1.81.6-1.81.9-0.90.6-1.5-1.51.21.72.21.71.71.4-1.6-1.6-1.4-1.61.6-2.0-0.3
Rest time, locomotor task time 11.01.12.7-0.1-0.40.8-0.40.8-0.91.0-0.80.7-1.0-1.00.81.31.41.31.31.0-1.2-1.3-1.1-1.41.4-1.6-0.8
Distance moved, locomotor task time 11.21.33.30.80.7-1.30.7-1.01.3-1.20.8-0.60.90.9-0.9-1.4-1.5-1.4-1.4-1.21.11.31.11.4-1.41.80.3
Vertical activity count, locomotor time 11.92.03.40.91.0-1.21.0-1.41.2-1.31.4-1.31.91.7-1.4-1.7-1.6-1.7-1.7-1.31.41.51.31.5-1.51.51.1
Time >=10cm from walls, locomotor time 20.00.00.20.30.1-0.50.1-0.20.3-0.20.1-0.1-0.3-0.20.2-0.20.0-0.2-0.2-0.10.10.20.10.1-0.1-0.3-0.1
Bouts of movement, locomotor time 20.80.92.1-1.4-1.31.4-1.41.1-1.11.2-0.60.4-0.8-0.80.80.81.00.90.80.8-0.8-0.8-0.8-0.80.8-0.90.0
Total resting periods, locomotor time 20.50.51.4-1.1-1.01.2-1.00.8-0.80.9-0.40.3-0.5-0.50.50.60.80.70.60.5-0.6-0.6-0.6-0.60.6-0.80.1
Rest time, locomotor task time 20.30.30.9-0.2-0.50.5-0.50.5-0.50.5-0.40.4-0.6-0.60.30.80.70.80.80.5-0.5-0.7-0.4-0.70.7-1.0-0.2
Distance moved, locomotor task time 20.20.31.00.60.5-0.90.4-0.40.7-0.6-0.00.20.00.1-0.1-0.5-0.8-0.6-0.5-0.60.20.40.20.5-0.51.0-0.5
Vertical activity count, locomotor time 20.70.81.30.90.7-0.80.6-0.80.9-0.90.7-0.60.80.9-0.9-1.1-1.1-1.1-1.1-0.90.81.00.81.0-1.01.10.5
Light reinforcement 12.54.66.92.22.1-1.92.6-2.62.2-2.02.4-2.42.62.3-2.4-1.9-1.4-1.9-1.9-2.22.12.02.22.1-2.11.81.1
Light reinforcement 21.72.26.22.12.1-2.02.5-1.71.6-1.71.1-0.81.81.5-1.3-1.2-1.5-1.2-1.1-1.11.41.21.31.2-1.21.40.1
Bone: marrow area0.20.51.60.0-0.10.1-0.5-0.30.4-0.50.6-0.60.60.7-0.7-0.7-0.7-0.7-0.7-0.70.70.70.70.9-0.90.91.3
Bone: maximum diameter0.71.24.52.01.9-1.91.8-0.71.3-1.4-0.40.90.40.4-0.4-0.5-2.1-0.5-0.5-0.40.40.40.40.6-0.61.4-0.9
Bone: maximum force2.84.811.13.33.3-3.33.3-2.52.8-2.71.3-0.81.71.7-1.8-1.8-2.6-1.7-1.7-1.81.81.81.81.6-1.62.3-0.6
Bone: maximum moment3.25.512.73.63.6-3.53.5-2.73.0-2.81.4-0.91.91.8-1.9-1.9-2.7-1.9-1.9-1.91.91.91.91.8-1.82.4-0.6
Mean time between licks in bursts0.71.02.6-1.4-1.61.3-1.01.3-1.21.1-0.80.6-1.0-1.00.90.81.00.80.80.9-0.9-0.8-0.9-0.70.7-0.70.2
Mean num. licks in bursts0.10.20.60.50.6-0.50.7-0.60.4-0.20.6-0.60.70.3-0.2-0.20.0-0.2-0.2-0.20.20.20.30.4-0.40.1-0.1
Cd content in liver0.40.41.7-1.1-1.31.0-1.10.1-0.40.40.6-0.80.30.3-0.5-0.40.5-0.4-0.4-0.40.40.40.4-0.10.1-0.31.1
Co content in liver0.20.31.1-0.0-0.00.10.0-0.60.2-0.10.9-1.10.60.6-0.6-0.60.1-0.5-0.6-0.60.60.60.60.5-0.50.10.8
Cu content in liver0.20.21.00.30.4-0.30.40.2-0.10.3-0.50.5-0.4-0.60.60.60.30.50.60.6-0.6-0.6-0.6-0.50.5-0.4-1.0
Fe content in liver0.20.31.2-1.1-0.90.9-0.60.5-0.60.4-0.0-0.1-0.3-0.20.10.10.60.20.10.1-0.1-0.1-0.1-0.30.3-0.70.9
K content in liver1.71.73.31.71.8-1.61.5-1.51.5-1.41.1-0.91.51.3-1.1-1.1-1.4-1.1-1.1-1.11.11.11.11.3-1.31.40.1
Mg content in liver0.80.92.00.50.5-0.30.3-1.10.7-0.61.3-1.41.21.1-0.9-0.9-0.3-1.0-0.9-0.90.90.90.91.2-1.20.80.9
Mn content in liver0.10.20.70.50.5-0.40.70.30.1-0.2-0.60.8-0.0-0.20.30.3-0.70.20.30.3-0.3-0.3-0.30.1-0.10.4-0.4
Na content in liver0.30.30.60.10.10.00.30.4-0.40.3-0.70.8-0.2-0.40.70.70.10.70.70.7-0.7-0.7-0.7-0.60.6-0.3-0.8
Rb content in liver2.22.83.61.21.1-1.31.2-1.91.7-1.61.9-1.81.81.8-1.8-1.8-1.2-1.9-1.8-1.81.81.81.81.8-1.81.61.1
Se content in liver0.50.60.90.70.6-0.60.5-0.70.8-0.90.7-0.60.80.9-1.0-0.9-0.9-0.9-0.9-0.90.90.90.90.9-0.90.70.8
Sr content in liver1.81.62.7-0.2-0.50.3-0.81.0-0.91.1-1.31.2-1.6-1.51.41.41.31.51.41.4-1.4-1.4-1.4-1.51.5-1.4-1.6
Zn content in liver1.21.32.50.1-0.00.2-0.20.9-0.80.9-1.31.3-1.2-1.31.31.30.81.31.31.3-1.3-1.3-1.3-1.21.2-1.0-1.6
Bone: minimum diameter2.03.78.62.92.8-2.92.6-2.12.4-2.41.0-0.61.61.4-1.6-1.6-2.5-1.5-1.5-1.61.61.61.51.6-1.62.1-0.3
Time in familiar zone, hab. session 10.10.10.5-0.2-0.40.2-0.1-0.2-0.00.10.4-0.60.20.2-0.1-0.20.4-0.2-0.2-0.20.20.20.2-0.10.1-0.70.4
Time in novel zone, hab. session 10.10.10.40.10.2-0.10.50.20.1-0.3-0.30.50.20.1-0.1-0.0-0.60.0-0.0-0.10.10.10.1-0.10.10.30.1
Total zone transitions, hab. session 10.30.41.1-0.5-0.50.4-0.8-0.30.0-0.00.9-1.10.40.6-0.6-0.60.3-0.6-0.6-0.50.60.60.60.6-0.60.31.1
Total locomotion distance, hab. session 11.62.33.40.70.7-0.80.9-1.61.3-1.31.8-1.81.71.7-1.8-1.7-1.1-1.7-1.7-1.71.71.71.71.6-1.61.31.5
Locomotion velocity, hab. session 11.42.13.40.80.7-0.80.6-1.61.3-1.21.8-1.81.51.6-1.7-1.6-0.9-1.7-1.6-1.61.61.61.61.6-1.61.41.3
Time in familiar zone, hab. session 20.20.21.2-0.4-0.50.4-0.2-0.1-0.0-0.10.5-0.60.40.4-0.4-0.50.2-0.4-0.4-0.40.40.40.40.0-0.0-0.61.1
Time in novel zone, hab. session 20.10.10.3-0.3-0.20.2-0.20.4-0.30.4-0.50.6-0.3-0.50.40.50.00.40.40.4-0.4-0.4-0.4-0.10.10.3-0.5
Total zone transitions, hab. session 21.01.34.4-0.3-0.10.2-0.4-1.10.5-0.41.8-2.11.21.3-1.3-1.20.3-1.3-1.2-1.21.21.21.21.3-1.30.71.6
Total locomotion distance, hab. session 22.22.96.20.90.9-0.91.1-2.01.5-1.32.3-2.52.01.8-1.9-1.8-0.5-1.9-1.8-1.81.81.81.81.8-1.81.51.4
Locomotion velocity, hab. session 22.23.05.81.21.2-1.11.2-2.11.6-1.42.3-2.42.01.9-1.9-1.8-0.7-1.9-1.9-1.81.81.91.81.8-1.81.61.2
Novel to familiar place preference ratio2.02.04.01.61.5-1.61.7-2.01.6-1.31.7-1.71.51.3-1.3-1.3-0.6-1.4-1.4-1.41.31.41.31.3-1.31.4-0.1
Novelty place preference1.71.73.41.51.4-1.61.6-1.81.5-1.21.5-1.51.31.2-1.2-1.2-0.6-1.2-1.2-1.21.21.21.21.2-1.21.2-0.2
Time in novel zone, NPP test1.81.83.51.41.3-1.51.5-1.91.5-1.21.7-1.71.41.3-1.3-1.3-0.5-1.3-1.3-1.31.31.31.31.3-1.31.30.1
Total zone transitions, NPP test0.71.03.0-0.5-0.40.4-0.2-0.80.4-0.31.5-1.70.91.1-1.1-1.10.1-1.2-1.1-1.11.11.11.11.1-1.10.81.6
Total locomotion distance, NPP test2.43.38.20.50.5-0.50.9-2.01.4-1.12.6-2.92.02.0-2.1-2.0-0.4-2.1-2.0-2.02.02.02.02.0-2.01.51.9
Locomotion velocity, NPP test2.02.86.90.60.6-0.71.1-2.01.4-1.12.4-2.61.81.9-1.9-1.9-0.4-1.9-1.9-1.91.81.91.81.8-1.81.41.6
Intraocular pressure0.91.22.50.70.5-0.90.2-1.41.2-0.91.5-1.61.11.0-1.2-1.1-0.4-1.1-1.2-1.31.31.21.41.3-1.30.80.7
Delta distance traveled before/after self-admin0.90.93.6-0.10.10.10.2-1.00.5-0.41.7-1.91.31.2-1.0-0.70.2-0.8-0.9-1.01.00.81.01.0-1.00.41.7
Delta ambulatory time before/after self-admin0.40.52.3-0.6-0.40.6-0.4-0.5-0.10.11.2-1.50.70.7-0.5-0.20.8-0.3-0.4-0.50.50.30.50.5-0.5-0.21.5
Parametrial fat weight0.81.74.52.01.9-2.11.7-1.51.7-1.60.9-0.61.01.0-1.0-1.1-1.4-1.0-1.1-1.01.11.01.01.0-1.00.7-0.2
Pavlov. Cond. lever latency1.31.78.3-0.9-1.01.0-0.9-0.40.1-0.41.5-1.71.51.6-1.3-1.4-0.5-1.3-1.4-1.41.41.31.41.2-1.20.52.9
Pavlov. Cond. magazine entry latency0.60.83.31.81.8-1.81.5-0.51.0-1.0-0.60.9-0.1-0.20.00.1-1.10.00.10.0-0.0-0.1-0.00.2-0.20.7-1.5
Pavlov. Cond. change in total contacts0.10.11.10.40.4-0.40.3-0.20.10.2-0.10.1-0.4-0.40.40.50.50.40.40.3-0.4-0.4-0.4-0.20.2-0.0-1.0
Pavlov. Cond. index score1.01.25.02.22.2-2.22.0-0.91.3-1.1-0.40.8-0.1-0.1-0.1-0.0-1.1-0.1-0.0-0.10.10.10.10.3-0.30.9-1.9
Pavlov. Cond. latency score0.91.15.41.81.8-1.91.8-0.40.8-0.6-0.91.3-0.6-0.70.50.5-0.70.40.50.5-0.5-0.5-0.5-0.30.30.4-2.3
Pavlov. Cond. lever contacts0.50.64.21.01.1-1.11.0-0.30.30.0-0.60.7-0.7-0.80.60.70.30.60.60.6-0.6-0.6-0.6-0.60.6-0.1-2.0
Pavlov. Cond. magazine entry number0.60.72.8-1.5-1.51.5-1.20.1-0.70.60.9-1.20.60.6-0.4-0.50.8-0.4-0.5-0.40.40.40.40.1-0.1-0.31.7
Pavlov. Cond. intertrial magazine entries0.60.82.20.20.2-0.20.2-1.00.6-0.41.3-1.51.11.0-0.9-1.0-0.3-0.9-0.9-0.90.90.90.91.1-1.10.70.9
Pavlov. Cond. lever-magazine prob. diff.1.11.35.32.22.3-2.32.1-1.11.5-1.3-0.10.50.20.1-0.3-0.2-1.2-0.3-0.3-0.30.30.30.30.5-0.51.1-1.7
Pavlov. Cond. response bias0.60.73.51.61.6-1.61.3-0.40.7-0.5-0.60.9-0.5-0.60.40.4-0.60.30.40.4-0.4-0.4-0.4-0.10.10.3-1.9
Pavlov. Cond. lever latency3.04.06.0-1.2-1.21.2-0.92.2-1.81.7-2.42.5-2.4-2.32.22.21.22.12.22.2-2.2-2.2-2.2-2.42.4-1.9-1.8
Pavlov. Cond. magazine entry latency1.11.25.5-0.9-1.10.8-1.6-0.40.1-0.11.5-1.81.11.2-1.1-1.10.3-1.0-1.1-1.11.11.11.10.7-0.7-0.12.3
Pavlov. Cond. change in total contacts1.31.84.5-0.2-0.20.1-0.5-1.20.7-0.71.9-2.11.61.6-1.5-1.5-0.3-1.5-1.5-1.51.51.51.51.4-1.41.02.0
Pavlov. Cond. index score2.02.55.30.20.1-0.2-0.3-1.41.0-1.12.2-2.31.91.9-1.9-1.8-0.6-1.8-1.8-1.81.91.81.81.7-1.71.02.3
Pavlov. Cond. latency score2.22.75.20.30.2-0.3-0.3-1.51.1-1.22.2-2.31.92.0-1.9-1.9-0.8-1.8-1.9-1.91.91.91.91.7-1.71.12.3
Pavlov. Cond. lever contacts3.54.87.01.51.4-1.41.1-2.42.1-2.02.6-2.52.62.5-2.4-2.4-1.5-2.4-2.4-2.42.42.42.42.5-2.52.11.9
Pavlov. Cond. magazine entry number1.41.76.20.70.8-0.61.10.8-0.30.4-1.92.1-1.7-1.51.41.3-0.11.31.41.4-1.4-1.4-1.4-1.11.1-0.3-2.5
Pavlov. Cond. intertrial magazine entries1.11.54.11.61.6-1.52.0-1.11.4-1.30.5-0.21.00.8-0.9-0.9-1.6-1.0-0.9-0.90.90.90.91.3-1.31.9-0.4
Pavlov. Cond. lever-magazine prob. diff.1.82.35.7-0.0-0.1-0.0-0.5-1.30.9-0.92.1-2.31.91.8-1.8-1.7-0.5-1.7-1.7-1.71.81.81.71.6-1.60.92.4
Pavlov. Cond. response bias2.23.05.60.60.5-0.60.3-1.71.4-1.32.3-2.42.22.0-2.0-1.9-0.8-1.9-1.9-2.02.02.02.01.9-1.91.32.1
Time in closed arm before self-admin0.80.91.7-1.3-1.20.8-1.21.1-0.90.9-0.90.8-1.2-1.21.00.80.90.80.80.8-0.8-0.8-0.8-0.80.8-0.9-0.4
Time in closed arm after self-admin2.52.65.1-1.3-1.61.0-1.61.8-1.31.4-1.81.8-2.2-2.11.91.61.31.61.61.4-1.5-1.6-1.4-1.61.6-1.6-1.4
Time in open arm before self-admin0.20.20.6-0.10.20.30.20.4-0.60.3-0.70.7-0.0-0.10.60.3-0.20.30.30.8-0.6-0.4-0.7-0.40.4-0.1-0.5
Time in open arm after self-admin0.20.20.60.10.2-0.10.2-0.50.2-0.30.6-0.60.70.7-0.8-0.4-0.2-0.4-0.3-0.40.40.40.40.6-0.60.50.6
Bone: periosteal estimation1.22.55.12.22.1-2.12.0-1.61.9-1.90.8-0.51.41.2-1.3-1.3-2.3-1.3-1.3-1.31.31.31.31.5-1.52.0-0.0
Bone: periosteal perimeter0.91.55.82.42.3-2.32.4-0.61.2-1.1-0.91.4-0.0-0.30.20.1-1.80.20.20.2-0.2-0.2-0.2-0.10.10.8-2.0
Bone: post-yield work0.10.20.80.0-0.0-0.10.1-0.60.3-0.10.8-0.90.30.5-0.5-0.4-0.0-0.4-0.4-0.50.50.40.50.4-0.40.30.3
Progressive ratio test 1 active lever presses0.60.61.61.31.2-0.71.2-1.00.8-0.80.8-0.71.00.8-0.7-0.8-0.6-0.6-0.6-0.70.50.30.70.6-0.60.30.1
Progressive ratio test 1 breakpoint0.70.71.71.31.3-0.81.3-1.10.9-0.80.9-0.81.10.9-0.7-0.8-0.6-0.6-0.6-0.70.50.30.70.6-0.60.20.2
Progressive ratio test 1 inactive lever presses3.13.45.82.42.3-2.12.3-2.12.1-2.11.4-1.21.91.8-1.8-1.8-2.2-1.8-1.7-1.71.71.61.81.8-1.81.90.3
Progressive ratio test 2 active lever presses0.20.20.70.80.8-0.60.8-0.60.6-0.50.4-0.30.50.4-0.4-0.3-0.3-0.2-0.2-0.40.30.10.40.2-0.20.1-0.1
Progressive ratio test 2 breakpoint0.30.40.80.90.9-0.70.9-0.80.8-0.70.6-0.50.60.6-0.6-0.5-0.5-0.4-0.5-0.60.50.30.60.4-0.40.20.1
Progressive ratio test 2 inactive lever presses0.30.30.90.80.9-0.80.9-0.60.7-0.70.3-0.10.50.4-0.5-0.5-0.7-0.3-0.3-0.50.40.20.60.4-0.40.4-0.2
Incentive Sensitization - Responses0.00.00.1-0.00.20.10.20.1-0.10.0-0.30.3-0.1-0.10.20.30.10.30.20.2-0.2-0.3-0.2-0.30.3-0.2-0.2
Incentive Sensitization - Breakpoint0.10.10.2-0.00.20.10.20.2-0.10.0-0.30.4-0.1-0.10.20.30.10.40.20.2-0.3-0.3-0.2-0.30.3-0.3-0.3
Sum of active levers in priming session hrs 5-60.60.61.40.40.7-0.50.7-0.90.7-0.71.0-1.01.21.1-0.7-0.7-0.6-0.7-0.8-0.80.80.70.80.8-0.80.80.7
Progressive ratio0.30.31.3-0.4-0.71.0-0.70.4-0.70.7-0.0-0.1-0.4-0.30.30.51.10.60.60.5-0.6-0.6-0.3-0.60.6-0.80.2
Food seeking constrained by brief footshock0.00.10.30.1-0.40.5-0.30.3-0.20.2-0.20.2-0.1-0.10.10.20.20.20.30.1-0.2-0.4-0.1-0.20.2-0.10.2
Seeking ratio, punishment vs. effort0.20.31.00.40.4-0.50.4-0.30.6-0.60.10.00.50.4-0.5-0.5-1.0-0.5-0.5-0.60.60.50.40.6-0.60.90.2
Retroperitoneal fat weight5.116.825.85.14.9-4.94.7-4.44.8-4.83.2-2.53.73.9-3.9-4.1-4.8-4.1-4.1-4.04.14.03.93.8-3.83.71.2
Reaction time number correct4.66.613.81.00.9-0.71.0-2.52.0-2.23.4-3.52.83.2-3.1-2.9-1.3-2.9-2.9-2.92.92.92.92.6-2.61.63.7
Reaction time mean minus median0.60.81.5-0.6-0.50.5-0.61.0-0.80.9-1.21.2-1.0-1.21.21.00.31.01.01.1-1.2-1.1-1.2-0.40.4-0.2-1.1
Reaction time mean minus median AUC0.20.31.10.30.2-0.40.10.40.10.0-0.81.0-0.6-0.60.50.4-0.50.40.30.3-0.5-0.5-0.50.2-0.20.6-1.0
Reaction time num false alarms0.10.20.7-0.5-0.80.5-0.80.4-0.40.5-0.1-0.0-0.8-0.60.30.30.70.30.30.2-0.2-0.1-0.10.0-0.0-0.3-0.0
Reaction time num false alarms AUC0.20.31.5-0.7-1.10.7-1.20.6-0.60.7-0.20.0-1.0-0.70.40.30.80.40.40.3-0.3-0.2-0.20.0-0.0-0.40.1
Reaction time trials correct on left4.66.613.81.00.9-0.71.0-2.52.0-2.23.4-3.52.83.2-3.1-2.9-1.3-2.9-2.9-2.92.92.92.92.6-2.61.63.7
Reaction time trials on left4.86.914.21.00.9-0.81.0-2.52.1-2.23.4-3.52.93.2-3.1-3.0-1.4-2.9-3.0-2.93.02.92.92.6-2.61.73.8
Reaction time mean0.30.51.00.40.5-0.50.2-0.60.6-0.70.6-0.50.60.8-0.6-0.8-0.9-0.7-0.8-0.70.70.70.71.0-1.01.00.6
Reaction time mean AUC0.50.71.30.40.5-0.50.4-0.70.7-0.80.8-0.80.90.9-0.8-0.9-0.9-0.9-0.9-0.90.80.80.81.1-1.11.10.8
Median of all reaction times0.60.91.20.60.5-0.60.2-0.80.8-0.90.9-0.90.91.1-1.0-1.1-1.0-1.1-1.1-1.11.11.01.11.0-1.01.01.0
Reaction time omissions0.30.41.40.60.6-0.70.5-0.40.6-0.80.20.00.70.6-0.4-0.7-1.2-0.7-0.6-0.50.50.60.50.9-0.91.00.3
Reaction time false alarm rate2.12.95.2-1.2-1.51.1-1.61.8-1.61.7-1.91.8-2.3-2.21.91.81.51.81.81.7-1.8-1.7-1.7-1.41.4-1.3-1.7
Reaction time premature initiation rate0.60.82.8-1.5-1.71.2-1.50.7-1.01.3-0.0-0.3-0.9-0.80.70.61.60.50.60.7-0.5-0.6-0.6-0.20.2-0.90.1
Reaction time premature initiations1.01.45.2-0.8-0.90.7-0.8-0.80.2-0.11.9-2.30.81.0-1.1-1.20.5-1.2-1.2-1.01.31.11.11.5-1.50.42.2
Std. dev. reaction times0.20.21.2-0.8-0.90.6-1.10.5-0.40.5-0.20.2-0.4-0.40.30.10.00.10.10.2-0.3-0.2-0.30.5-0.50.40.3
Reaction time trials completed4.86.914.21.00.9-0.81.0-2.52.1-2.23.4-3.52.93.2-3.1-3.0-1.4-2.9-3.0-2.93.02.92.92.6-2.61.73.8
Reaction time trials AUC5.07.214.31.11.0-0.81.1-2.62.2-2.33.5-3.62.93.3-3.2-3.0-1.4-3.0-3.0-3.03.03.03.02.7-2.71.73.8
Run reversals in cocaine runway, females0.40.41.8-0.5-0.90.4-0.9-0.10.1-0.10.7-0.90.20.4-0.7-0.50.1-0.5-0.5-0.70.80.50.70.6-0.60.51.4
Run reversals in cocaine runway, males0.30.30.80.80.6-0.30.60.00.00.0-0.50.5-0.3-0.30.50.80.40.60.70.4-0.5-0.7-0.5-0.70.7-0.7-0.9
Latency to leave start box in cocaine runway0.50.61.6-1.1-0.81.0-0.70.6-1.00.9-0.1-0.1-0.2-0.30.70.71.20.70.70.6-0.7-0.7-0.8-0.80.8-1.10.4
Latency to leave start box in cocaine runway, F0.10.10.8-0.7-0.50.2-0.3-0.1-0.10.10.5-0.70.30.3-0.2-0.20.5-0.2-0.2-0.20.20.20.10.0-0.0-0.20.9
Latency to leave start box in cocaine runway, M0.60.61.8-0.5-0.30.8-0.30.4-0.91.0-0.20.0-0.3-0.40.91.01.31.01.00.8-0.8-1.0-0.8-0.90.9-1.2-0.4
Std. dev. time between licks in bursts2.63.14.71.00.9-1.01.5-1.81.6-1.72.0-2.02.21.9-2.0-2.0-1.4-2.0-1.9-2.02.02.02.01.7-1.71.41.8
Total sessions with >9 infusions0.50.61.1-0.6-0.61.1-0.60.9-1.00.8-0.80.8-0.5-0.60.80.80.60.80.80.8-0.9-1.0-0.7-0.80.8-0.8-0.2
Short access day 1 total inactive lever presses0.10.10.50.70.6-0.40.6-0.20.3-0.3-0.10.20.30.1-0.1-0.2-0.4-0.1-0.0-0.10.1-0.10.10.1-0.10.1-0.3
Short access day 10 total inactive lever presses2.72.95.42.12.1-2.32.1-1.82.2-2.11.0-0.71.41.5-1.5-1.5-2.3-1.6-1.6-1.61.51.51.61.6-1.61.80.0
Short access day 1 total infusions0.80.91.7-1.1-1.21.3-1.21.1-1.11.0-0.80.7-0.9-0.90.80.91.00.90.80.8-0.9-1.0-0.7-0.80.8-1.0-0.1
Short access day 10 total infusions0.20.21.10.91.0-0.61.0-0.60.5-0.50.3-0.20.60.4-0.4-0.1-0.3-0.1-0.0-0.30.2-0.10.30.1-0.10.0-0.3
Short access total infusions0.10.10.2-0.00.00.30.00.1-0.20.2-0.10.00.0-0.10.10.30.40.40.30.2-0.3-0.5-0.2-0.30.3-0.4-0.1
Short access day 1 locomotion1.11.11.9-0.5-0.60.7-0.61.0-0.90.9-1.21.2-1.0-1.11.01.31.01.31.21.1-1.2-1.4-1.0-1.31.3-1.3-1.0
Short access day 10 total locomotion0.70.81.2-0.6-0.50.4-0.50.9-0.70.8-1.01.0-0.9-1.00.81.10.81.01.00.9-1.0-1.1-0.9-1.01.0-0.9-0.9
Short access total locomotion1.81.93.0-0.9-0.81.1-0.81.4-1.31.3-1.41.4-1.3-1.31.31.71.31.61.61.4-1.6-1.7-1.4-1.61.6-1.7-1.1
One hour access (0.3 mA shock)1.41.72.61.31.5-1.31.5-1.61.4-1.41.5-1.41.51.4-1.3-1.3-1.0-1.2-1.2-1.31.31.11.31.2-1.20.80.8
Compulsive drug intake1.21.22.00.70.8-1.20.8-1.31.3-1.21.3-1.21.01.0-1.1-1.1-0.9-1.2-1.2-1.31.41.31.21.1-1.10.90.8
One hour access (shock baseline)0.10.10.60.60.8-0.30.8-0.30.2-0.20.00.00.40.3-0.10.10.00.30.20.1-0.2-0.4-0.0-0.10.1-0.3-0.3
Social response proportion0.40.41.9-0.2-0.4-0.0-0.1-0.30.4-0.30.5-0.60.20.4-0.5-0.6-0.6-0.7-0.6-0.70.50.60.71.3-1.31.40.5
Social responses0.60.82.00.60.2-0.60.3-0.70.9-0.80.7-0.60.40.6-0.9-0.9-0.9-0.9-0.9-1.10.80.90.91.4-1.41.40.5
Social time0.20.30.7-0.1-0.10.1-0.0-0.50.3-0.20.8-0.90.60.6-0.7-0.6-0.3-0.6-0.6-0.70.50.70.70.7-0.70.50.6
Soleus weight0.72.16.22.42.5-2.42.1-2.11.8-1.51.2-1.10.91.0-1.0-1.0-1.0-0.9-1.0-1.01.01.11.01.1-1.11.2-0.9
Bone: stiffness0.20.31.10.90.9-1.01.0-0.30.7-0.7-0.20.40.20.2-0.3-0.3-1.0-0.2-0.2-0.30.30.30.30.1-0.10.6-0.5
Tibialis anterior weight0.00.10.4-0.2-0.20.1-0.6-0.20.00.10.5-0.60.00.2-0.2-0.10.5-0.1-0.1-0.10.10.10.10.1-0.1-0.10.3
Time to tail flick, vehicle, before self-admin0.00.00.20.30.4-0.50.3-0.30.3-0.10.2-0.20.20.1-0.20.20.10.20.1-0.10.10.00.1-0.00.00.0-0.3
Time to tail flick, vehicle, after self-admin1.92.02.9-1.5-1.61.4-1.61.6-1.61.6-1.41.2-1.7-1.71.51.21.31.31.31.5-1.3-1.2-1.5-1.31.3-1.2-0.8
Time to tail flick, test, before self-admin0.10.10.2-0.2-0.30.1-0.20.3-0.20.2-0.30.4-0.4-0.40.40.10.00.10.10.3-0.2-0.1-0.3-0.10.1-0.1-0.3
Time to tail flick, test, after self-admin0.10.10.30.1-0.2-0.3-0.20.10.2-0.3-0.20.3-0.00.0-0.2-0.1-0.5-0.0-0.1-0.20.30.20.30.2-0.20.6-0.0
Delta time to tail flick, vehicle, before/after SA0.20.20.60.0-0.20.1-0.1-0.20.1-0.10.5-0.60.10.2-0.1-0.8-0.2-0.7-0.7-0.30.40.60.30.5-0.50.20.6
Delta time to tail flick, test, before/after SA0.10.10.3-0.3-0.50.5-0.60.6-0.30.2-0.40.5-0.3-0.30.00.40.00.40.30.2-0.3-0.3-0.1-0.20.20.00.1
Tibia length3.18.727.95.25.3-5.24.8-1.93.5-3.8-1.02.21.00.9-1.1-1.2-5.1-1.3-1.2-1.21.21.21.21.8-1.83.6-2.7
Ambulatory time before self-admin1.51.54.21.51.6-1.71.6-1.11.5-1.60.40.01.01.1-1.0-1.2-2.0-1.1-1.0-1.11.01.11.11.0-1.01.6-0.2
Ambulatory time after self-admin1.61.72.80.71.1-0.91.1-1.41.2-1.21.5-1.51.61.7-1.3-1.3-1.1-1.3-1.3-1.41.31.31.41.4-1.41.41.2
Bone: tissue strength2.82.74.21.61.6-1.61.6-2.11.8-1.61.9-1.81.81.7-1.7-1.6-1.0-1.7-1.7-1.61.71.71.71.6-1.61.40.7
Total heroin consumption0.10.10.80.40.3-0.10.4-0.00.1-0.3-0.20.40.50.5-0.2-0.3-0.9-0.3-0.3-0.10.00.20.10.2-0.20.6-0.1
Bone: trabecular number0.10.10.3-0.4-0.30.3-0.60.3-0.40.5-0.30.2-0.4-0.50.40.40.40.40.40.5-0.4-0.4-0.4-0.20.20.0-0.4
Bone: trabecular spacing4.55.98.31.01.1-1.11.6-2.02.1-2.42.3-2.22.62.9-2.8-2.8-2.4-2.8-2.8-2.82.82.82.82.7-2.72.52.7
Bone: trabecular thickness0.91.13.50.10.1-0.1-0.30.4-0.61.0-0.80.8-0.9-1.31.31.21.01.21.31.3-1.3-1.3-1.3-1.01.0-0.9-1.9
Bone: trabecular tissue density0.71.01.7-1.0-1.11.0-1.01.3-1.11.0-1.21.1-1.2-1.01.01.00.61.01.01.0-1.0-1.0-1.1-0.80.8-0.7-0.4
Water consumed over 24 hours0.20.20.50.10.2-0.00.30.2-0.30.4-0.40.4-0.0-0.40.60.60.50.60.60.6-0.6-0.6-0.6-0.60.6-0.6-0.7
Number of responses in last shaping day0.40.42.41.11.5-0.91.5-0.40.5-0.7-0.30.60.70.4-0.3-0.1-0.9-0.2-0.2-0.0-0.00.00.00.0-0.00.4-0.9