Hub : Genes

Sf3b6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC mRNA stability Sf3b6 0.31 0.14 1.4e-07 0.22 0.26 0.22 0.23 5.0e-06 5.4e-07 5.6e-06 3.8e-06
2 BLA mRNA stability Sf3b6 0.09 0.05 8.0e-06 0.11 0.09 0.09 0.1 1.6e-06 2.2e-05 1.8e-05 8.3e-06
3 NAcc mRNA stability Sf3b6 0.08 0.04 2.0e-14 0.15 0.14 0.13 0.14 1.0e-16 1.3e-15 2.6e-15 2.2e-15
4 PL gene expression Sf3b6 0.06 0.03 2.4e-10 0.1 0.1 0.1 0.11 2.3e-11 2.6e-11 1.0e-10 1.0e-11
5 RMTg mRNA stability Sf3b6 0.18 0.12 3.2e-03 0.09 0.08 0.07 0.06 2.1e-03 3.3e-03 6.5e-03 1.0e-02
6 NAcc gene expression Sf3b6 0.06 0.04 9.4e-09 0.07 0.08 0.07 0.07 4.3e-08 2.2e-09 9.6e-09 1.0e-08
7 pVTA mRNA stability Sf3b6 0.19 0.09 3.0e-10 0.25 0.25 0.24 0.25 4.6e-11 4.5e-11 5.5e-11 2.4e-11
8 BLA gene expression Sf3b6 0.07 0.05 3.1e-04 0.07 0.06 0.06 0.06 1.5e-04 5.8e-04 2.9e-04 2.2e-04
9 PL mRNA stability Sf3b6 0.14 0.06 0.0e+00 0.22 0.23 0.23 0.23 1.3e-23 1.5e-24 1.6e-24 8.9e-25
10 pVTA gene expression Sf3b6 0.1 0.07 1.2e-04 0.1 0.11 0.1 0.1 3.1e-05 1.3e-05 3.7e-05 3.5e-05
11 Adipose gene expression Sf3b6 0.05 0.03 1.1e-06 0.04 0.04 0.03 0.03 2.3e-05 4.2e-05 1.9e-04 1.2e-04
12 LHb gene expression Sf3b6 0.1 0.08 8.5e-03 0.08 0.06 0.02 0.03 7.2e-03 1.4e-02 1.0e-01 5.3e-02
13 Liver gene expression Sf3b6 0.04 0.03 9.3e-04 0.01 0.02 0.02 0.01 1.4e-02 1.8e-03 4.8e-03 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density6.110.214.63.8-3.0-3.03.3-3.23.13.2-3.43.32.9-3.2-3.22.7
Area under the delay curve0.10.10.3-0.00.40.4-0.40.3-0.5-0.30.2-0.3-0.50.30.0-0.5
BMI with tail1.13.45.7-2.41.91.9-2.11.8-2.0-1.81.8-1.8-1.81.81.3-1.6
BMI without tail1.42.93.8-1.81.51.5-1.81.2-1.9-1.51.9-1.8-1.91.61.4-1.8
Body weight1.04.36.8-2.62.52.5-2.32.1-2.1-2.01.9-1.9-1.91.81.3-1.7
Weight adjusted by age0.10.10.3-0.60.30.3-0.20.2-0.1-0.20.2-0.2-0.00.1-0.10.0
Bone surface1.62.85.02.2-1.4-1.41.7-1.81.51.8-1.91.81.5-1.7-1.51.4
Bone volume3.05.18.52.9-2.1-2.12.3-2.32.12.3-2.52.42.0-2.2-2.21.8
Breakpoint value in progressive ratio session1.82.03.71.9-1.4-1.41.5-1.41.21.4-1.31.41.0-1.4-1.80.9
Number of licking bursts0.70.81.8-1.31.01.0-1.10.9-0.9-1.00.8-0.9-0.81.00.3-0.6
Context. condit. distance diff. score2.42.93.71.7-1.7-1.71.7-1.81.71.7-1.71.71.6-1.6-1.91.6
Locomotion velocity, session 10.10.10.4-0.3-0.1-0.1-0.30.4-0.4-0.30.3-0.3-0.30.30.6-0.4
Locomotion distance, session 10.10.10.30.3-0.5-0.50.3-0.20.20.2-0.10.20.2-0.2-0.20.1
Locomotion velocity, session 20.10.10.2-0.4-0.1-0.1-0.30.3-0.4-0.40.4-0.4-0.30.40.3-0.3
Locomotion distance, session 20.10.20.3-0.20.30.3-0.40.5-0.5-0.50.4-0.4-0.50.50.4-0.5
Locomotion velocity, session 30.30.40.70.4-0.7-0.70.5-0.40.60.5-0.60.60.7-0.5-0.80.7
Locomotion distance, session 30.40.41.20.6-0.3-0.30.6-0.30.70.5-0.70.70.7-0.7-1.10.8
Stereotopy head waving bouts, day 33.33.96.82.3-2.6-2.62.1-2.21.72.0-1.81.81.6-1.7-1.61.4
Stereotopy head waving duration, day 30.50.71.50.8-1.2-1.20.8-1.00.70.8-0.70.60.7-0.6-0.40.6
Locomotion velocity, session 70.10.10.30.5-0.5-0.50.4-0.30.30.3-0.40.40.3-0.4-0.30.2
Locomotion distance, session 70.00.00.1-0.0-0.2-0.20.1-0.10.10.1-0.10.20.1-0.2-0.20.2
Stereotopy head waving bouts, day 70.10.10.2-0.30.30.3-0.40.2-0.4-0.30.4-0.4-0.40.50.0-0.4
Stereotopy head waving duration, day 70.00.00.1-0.0-0.3-0.30.0-0.10.10.00.0-0.10.00.1-0.30.0
Locomotion velocity, session 82.32.74.71.6-2.2-2.21.6-1.81.51.6-1.51.41.5-1.3-1.61.4
Locomotion distance, session 81.92.73.61.8-1.7-1.71.7-1.71.61.6-1.61.61.5-1.5-1.91.4
Degree of sensitization distance0.20.20.4-0.6-0.1-0.1-0.40.1-0.6-0.30.5-0.5-0.50.50.6-0.5
Degree of sensitization stereotypy1.41.51.9-1.31.21.2-1.41.1-1.2-1.31.3-1.3-1.31.40.9-1.2
Conditioned locomotion3.54.14.62.1-1.7-1.72.1-2.12.12.1-2.12.12.1-2.1-2.12.0
Cocaine response after cond. corrected0.60.71.0-0.41.01.0-0.80.8-0.8-0.80.7-0.8-1.00.80.4-1.0
Cocaine response after cond. not corrected0.70.81.1-0.51.01.0-0.90.8-0.9-0.90.8-0.9-1.10.90.7-1.1
Cocaine response before conditioning0.10.20.30.3-0.5-0.50.5-0.40.50.3-0.20.30.5-0.30.20.4
Saline control response0.30.41.11.0-0.8-0.80.7-0.50.50.6-0.60.60.4-0.6-0.30.3
Bone: connectivity density3.65.78.52.9-2.3-2.32.4-2.52.22.5-2.52.52.1-2.3-2.31.9
Bone: cortical apparent density0.50.61.7-0.10.50.5-0.70.6-1.1-0.70.8-0.8-1.20.80.6-1.3
Bone: cortical area0.20.30.6-0.40.80.8-0.50.6-0.4-0.50.2-0.3-0.30.40.6-0.3
Bone: cortical porosity0.70.81.31.0-0.5-0.50.9-0.81.10.8-0.90.91.0-0.9-1.11.0
Bone: cortical porosity0.50.50.90.9-0.3-0.30.7-0.60.90.7-0.80.70.7-0.7-1.00.7
Bone: cortical thickness1.62.74.0-1.32.02.0-1.71.9-1.6-1.81.3-1.4-1.51.51.6-1.5
Bone: cortical thickness0.00.00.20.40.10.10.00.2-0.1-0.1-0.0-0.0-0.20.1-0.0-0.3
Bone: cortical tissue density0.50.61.7-0.10.50.5-0.70.6-1.1-0.70.8-0.8-1.20.80.6-1.3
Condit. Reinf. active minus inactive responses2.73.03.9-2.01.61.6-1.91.8-1.9-1.81.7-1.8-1.81.81.4-1.7
Condit. Reinf. active-inactive response ratio1.11.21.6-1.31.01.0-1.21.2-1.2-1.11.1-1.1-1.11.10.9-1.0
Condit. Reinf. active responses0.50.60.8-0.90.70.7-0.80.9-0.8-0.80.7-0.8-0.80.80.4-0.7
Condit. Reinf. inactive responses0.60.81.11.1-0.8-0.80.9-0.80.90.8-0.90.90.8-0.9-1.00.7
Incentive salience index mean1.01.21.8-1.31.01.0-1.21.2-1.1-1.21.0-1.1-1.11.20.8-1.0
Condit. Reinf. lever presses0.10.10.3-0.40.40.4-0.40.5-0.2-0.50.2-0.3-0.20.40.3-0.2
Condit. Reinf. active minus inactive responses0.10.10.20.3-0.5-0.50.3-0.40.20.3-0.20.20.2-0.1-0.20.1
Condit. Reinf. active-inactive response ratio0.00.00.1-0.30.10.1-0.20.2-0.0-0.20.2-0.2-0.10.20.1-0.0
Condit. Reinf. active responses0.30.40.7-0.40.40.4-0.60.5-0.7-0.60.6-0.7-0.70.70.8-0.7
Condit. Reinf. inactive responses0.20.20.7-0.30.30.3-0.40.3-0.6-0.40.4-0.4-0.50.40.8-0.6
Condit. Reinf. lever presses0.50.61.2-0.50.10.1-0.80.3-0.9-0.60.9-1.0-1.01.11.0-1.1
Condit. Reinf. lever reinforcers received0.40.61.1-0.50.40.4-0.70.6-0.9-0.80.8-0.8-0.90.91.0-1.0
Conditioned reinforcement - actives0.60.61.61.3-0.5-0.50.8-0.50.80.6-0.80.80.6-0.7-0.90.5
Conditioned reinforcement - inactives0.40.51.41.2-0.5-0.50.8-0.50.90.6-0.70.70.7-0.7-0.60.5
Conditioned locomotion0.40.51.10.60.90.9-0.31.0-0.5-0.80.4-0.4-0.70.40.8-0.9
Patch foraging indifference point 0 sec0.60.91.10.7-0.9-0.91.0-1.01.01.1-0.91.01.0-1.0-1.01.1
Patch foraging indifference point AUC0.60.71.30.2-0.8-0.80.7-1.11.00.8-0.70.71.1-0.8-0.71.1
Delay disc. indifference point, 0s delay1.71.82.7-1.11.21.2-1.61.1-1.4-1.41.4-1.5-1.51.70.9-1.4
Delay disc. indifference point, 16s delay0.00.00.00.20.10.1-0.0-0.0-0.10.0-0.20.1-0.10.0-0.1-0.1
Delay disc. indifference point, 2s delay1.21.32.0-0.71.01.0-1.20.9-1.2-1.11.2-1.3-1.41.30.8-1.4
Delay disc. indifference point, 24s delay1.21.13.11.8-0.8-0.81.2-0.80.90.9-1.31.20.7-1.2-1.00.5
Delay disc. indifference point, 4s delay0.10.20.3-0.30.50.5-0.50.5-0.3-0.50.3-0.4-0.40.5-0.1-0.3
Delay disc. indifference point, 8s delay0.00.00.20.4-0.0-0.00.1-0.0-0.20.1-0.10.1-0.2-0.1-0.3-0.3
Indifference point function ln k0.00.10.50.7-0.1-0.10.10.2-0.1-0.1-0.00.0-0.20.10.2-0.4
Indifference point function log k0.00.10.50.7-0.1-0.10.10.2-0.1-0.1-0.00.0-0.20.10.2-0.4
Patch foraging total patch changes 0 sec0.61.01.20.7-1.0-1.01.0-1.01.01.1-0.91.01.0-1.0-1.01.0
Patch foraging total patch changes 12 sec0.10.10.4-0.5-0.2-0.20.1-0.40.40.3-0.30.20.5-0.3-0.50.6
Patch foraging total patch changes 18 sec2.12.74.41.1-1.7-1.71.5-2.11.61.8-1.41.51.6-1.5-1.91.6
Patch foraging total patch changes 24 sec0.00.00.2-0.30.30.30.0-0.10.10.1-0.10.10.1-0.2-0.40.2
Patch foraging total patch changes 6 sec0.30.40.9-0.2-0.7-0.70.5-0.70.70.6-0.60.50.8-0.6-0.71.0
Patch foraging time to switch 0 sec0.20.40.6-0.30.80.8-0.70.6-0.7-0.60.5-0.5-0.80.60.1-0.8
Patch foraging water rate 0 sec1.32.02.61.6-1.5-1.51.6-1.21.51.3-1.41.41.4-1.5-1.21.3
Patch foraging water rate 12 sec1.21.82.9-1.01.71.7-1.31.7-1.2-1.41.2-1.2-1.21.21.2-1.2
Patch foraging water rate 18 sec0.20.20.6-0.10.60.6-0.30.8-0.1-0.60.5-0.4-0.30.40.5-0.4
Patch foraging water rate 24 sec0.00.00.10.2-0.1-0.10.20.00.10.1-0.20.20.1-0.2-0.10.1
Patch foraging water rate 6 sec0.20.30.8-0.30.60.6-0.30.9-0.3-0.60.5-0.4-0.40.30.3-0.4
Seeking ratio, delayed vs. immediate footshock0.10.20.6-0.8-0.0-0.0-0.40.0-0.3-0.20.5-0.5-0.20.50.6-0.1
Distance traveled before self-admin0.10.10.2-0.30.10.1-0.30.0-0.4-0.10.4-0.4-0.50.30.1-0.4
Distance traveled after self-admin0.30.41.00.2-0.9-0.90.6-1.00.50.8-0.40.40.5-0.5-0.40.5
Extensor digitorum longus weight0.41.74.02.0-1.5-1.51.4-1.51.11.3-1.21.10.9-1.1-1.30.7
Bone: elastic displacement0.30.30.90.9-0.5-0.50.6-0.60.50.5-0.60.50.4-0.5-0.30.3
Bone: elastic work0.10.10.70.8-0.3-0.30.5-0.20.30.3-0.50.40.2-0.4-0.20.1
Bone: endosteal estimation0.92.02.61.4-1.6-1.61.4-1.61.41.5-1.31.41.4-1.4-1.31.3
Bone: endosteal perimeter0.30.70.90.7-0.7-0.70.8-1.00.91.0-0.80.91.0-0.9-0.51.0
Epididymis fat weight3.58.120.2-4.53.03.0-3.23.0-2.7-2.72.4-2.5-2.02.52.8-1.6
Delta time in closed arm before/after self-admin0.70.71.80.4-0.8-0.80.7-0.80.90.8-0.80.70.8-0.7-1.40.9
Delta time in open arm before/after self-admin0.30.30.5-0.50.50.5-0.40.5-0.7-0.40.7-0.5-0.60.20.7-0.6
Diff in mean of infusions in LGA sessions0.20.20.40.3-0.5-0.50.4-0.60.40.6-0.30.40.4-0.4-0.60.4
Delay discount exponential model param0.00.00.1-0.3-0.1-0.1-0.0-0.10.10.00.1-0.00.20.00.30.2
Extinction: sum of active levers before priming0.50.51.80.5-0.7-0.70.7-0.70.70.7-0.40.50.6-0.6-1.30.6
Active lever presses in extinction session 60.60.60.80.4-0.8-0.80.8-0.90.90.9-0.50.70.9-0.8-0.80.9
Bone: final force0.20.30.5-0.70.70.7-0.60.6-0.4-0.60.4-0.5-0.40.60.4-0.3
Bone: final moment0.10.10.2-0.50.40.4-0.40.4-0.3-0.40.3-0.4-0.30.40.4-0.2
Food consumed during 24 hour testing period0.10.10.2-0.4-0.4-0.4-0.1-0.50.10.20.1-0.20.10.30.00.2
Glucose0.00.00.10.00.30.3-0.0-0.10.00.2-0.20.10.0-0.1-0.30.1
Heart weight1.92.75.1-2.31.81.8-1.81.6-1.5-1.61.5-1.6-1.31.61.6-1.2
Delay discount hyperbolic model param0.10.10.2-0.1-0.3-0.30.2-0.30.40.3-0.10.20.5-0.20.00.5
Intermittent access intake day 1-15 change0.80.82.71.7-0.8-0.81.0-0.70.80.8-0.90.90.6-0.9-0.70.5
Intermittent access intake escalation1.51.53.21.8-1.2-1.21.3-1.11.11.1-1.21.21.0-1.2-1.30.9
Intermittent access intake escalation 20.80.81.51.2-1.1-1.10.9-1.00.80.9-0.90.90.7-0.8-0.80.7
Intermitt. access day 1 inactive lever presses0.10.10.3-0.50.50.5-0.40.5-0.1-0.40.1-0.2-0.10.3-0.0-0.1
Intermitt. access day 15 inactive lever presses0.80.91.30.4-1.0-1.00.9-1.01.01.0-1.00.81.1-0.8-0.51.1
Intermitt. access escalation Index1.71.52.0-1.21.31.3-1.21.3-1.3-1.31.4-1.2-1.21.11.0-1.2
Intermittent access day 1 total infusions0.00.00.10.4-0.1-0.10.2-0.10.30.1-0.10.10.1-0.1-0.20.0
Intermittent access day 15 total infusions0.10.10.70.9-0.2-0.20.3-0.10.20.2-0.20.20.0-0.2-0.2-0.1
Intermittent access terminal intake (last 3 days)0.30.30.60.00.40.4-0.40.5-0.4-0.50.6-0.6-0.60.60.8-0.7
Intermittent access total infusions0.00.10.10.40.30.3-0.00.3-0.1-0.20.1-0.1-0.20.20.1-0.3
Intermittent access day 1 locomotion0.60.61.0-0.00.90.9-0.60.9-0.7-0.80.7-0.7-0.90.80.6-1.0
Intermittent access day 15 total locomotion0.30.30.5-0.20.70.7-0.50.7-0.4-0.70.4-0.5-0.50.50.5-0.5
Intermittent access total locomotion0.91.01.8-0.31.31.3-0.91.4-0.9-1.20.8-0.8-1.00.90.8-1.1
Intermittent access standard deviation0.10.10.60.5-0.4-0.40.2-0.30.30.3-0.30.30.2-0.2-0.80.3
Left kidney weight0.10.10.4-0.40.50.5-0.30.3-0.3-0.30.3-0.4-0.30.20.6-0.3
Right kidney weight0.10.41.1-1.00.90.9-0.70.5-0.5-0.40.5-0.5-0.30.40.6-0.2
Cocaine induced anxiety3.54.04.82.2-2.0-2.02.1-2.01.92.0-2.12.11.9-2.0-1.91.8
Post-drug Anxiety1.11.31.70.7-1.1-1.11.1-1.21.21.2-1.11.11.3-1.1-0.91.3
Baseline Anxiety1.92.03.4-1.81.31.3-1.51.3-1.3-1.41.5-1.5-1.21.41.5-1.1
Tail length0.00.00.1-0.10.20.20.0-0.3-0.10.10.2-0.2-0.1-0.10.2-0.2
Length with tail0.31.02.1-1.01.51.5-1.01.0-0.9-0.90.8-0.9-0.90.80.7-0.8
Length without tail0.10.10.4-0.30.70.7-0.30.7-0.1-0.4-0.0-0.1-0.00.2-0.10.1
Times rat made contact with spout2.22.63.51.6-1.8-1.81.6-1.61.61.5-1.51.51.5-1.4-1.91.5
Lifetime Intake0.00.00.30.50.20.20.10.20.1-0.10.00.0-0.1-0.0-0.1-0.2
Liver weight, left4.06.38.2-2.92.52.5-2.62.4-2.5-2.52.6-2.6-2.42.52.3-2.3
Liver weight, right1.42.35.8-2.41.51.5-1.61.5-1.4-1.51.5-1.5-1.21.31.4-0.9
Locomotor activity0.81.32.6-1.61.31.3-1.31.3-1.1-1.21.0-1.0-0.91.00.9-0.8
Locomotor testing distance0.20.31.1-1.00.70.7-0.70.7-0.5-0.60.4-0.4-0.30.40.3-0.2
Locomotor testing rearing0.10.10.3-0.50.50.5-0.40.4-0.3-0.30.3-0.3-0.20.20.3-0.2
Locomotion in novel chamber3.03.74.1-1.92.02.0-2.01.9-2.0-1.91.9-1.9-2.01.91.7-1.9
Locomotion in novel chamber post-restriction0.60.81.4-1.00.60.6-1.00.6-0.8-0.80.8-1.0-0.81.11.2-0.8
Fecal boli incidents, locomotor time 10.90.92.81.7-0.8-0.81.1-0.80.90.9-1.01.00.6-1.0-1.00.5
Change in fecal boli incidents, locomotor task0.40.41.0-1.00.70.7-0.80.7-0.4-0.70.5-0.5-0.30.70.3-0.1
Time >=10cm from walls, locomotor time 10.70.71.41.1-1.1-1.11.0-1.20.51.0-0.70.80.5-0.9-0.10.4
Bouts of movement, locomotor time 10.10.10.20.4-0.5-0.50.4-0.40.00.40.00.10.0-0.30.0-0.1
Total resting periods, locomotor time 10.50.60.90.9-0.9-0.90.9-0.90.50.9-0.50.70.6-0.8-0.30.4
Rest time, locomotor task time 10.10.10.30.5-0.3-0.30.4-0.20.10.2-0.10.20.2-0.30.50.1
Distance moved, locomotor task time 10.50.51.0-1.00.80.8-0.80.6-0.7-0.70.7-0.8-0.70.70.2-0.6
Vertical activity count, locomotor time 11.01.11.5-0.81.11.1-1.11.0-1.1-1.01.1-1.1-1.21.00.5-1.2
Time >=10cm from walls, locomotor time 21.61.72.81.7-1.5-1.51.4-1.51.01.4-1.31.20.9-1.3-0.80.8
Bouts of movement, locomotor time 20.10.10.2-0.10.20.2-0.40.3-0.3-0.30.1-0.3-0.30.40.4-0.4
Total resting periods, locomotor time 20.00.00.00.1-0.0-0.0-0.10.1-0.1-0.0-0.1-0.0-0.00.20.2-0.1
Rest time, locomotor task time 20.20.20.30.5-0.5-0.50.5-0.40.30.5-0.40.50.4-0.6-0.00.3
Distance moved, locomotor task time 20.91.11.5-1.11.01.0-1.00.9-1.0-1.01.2-1.2-1.11.00.8-1.1
Vertical activity count, locomotor time 20.20.20.5-0.30.30.3-0.40.4-0.5-0.40.7-0.6-0.70.40.3-0.7
Light reinforcement 10.10.10.2-0.30.40.4-0.30.4-0.3-0.40.3-0.3-0.40.30.2-0.4
Light reinforcement 20.10.10.80.90.20.20.3-0.10.40.1-0.40.30.2-0.2-0.60.1
Bone: marrow area0.81.82.31.3-1.5-1.51.4-1.51.31.4-1.21.31.3-1.3-1.21.2
Bone: maximum diameter0.40.71.10.7-0.7-0.70.8-0.90.90.9-1.00.91.1-0.9-0.51.1
Bone: maximum force0.00.10.2-0.40.30.3-0.30.2-0.1-0.30.2-0.3-0.20.30.1-0.1
Bone: maximum moment0.00.00.0-0.20.00.0-0.10.0-0.0-0.10.0-0.1-0.00.10.00.0
Mean time between licks in bursts0.10.20.5-0.7-0.7-0.7-0.2-0.4-0.30.10.3-0.2-0.10.20.6-0.1
Mean num. licks in bursts2.63.14.62.2-2.0-2.01.9-1.81.71.8-1.61.71.6-1.7-1.41.4
Cd content in liver0.20.20.60.2-0.5-0.50.5-0.80.50.7-0.20.40.5-0.5-0.40.4
Co content in liver0.00.10.10.20.30.3-0.10.1-0.0-0.20.3-0.3-0.20.20.2-0.3
Cu content in liver0.00.00.10.1-0.1-0.10.1-0.30.00.2-0.20.20.1-0.3-0.40.1
Fe content in liver2.12.53.01.4-1.5-1.51.6-1.41.71.5-1.61.61.7-1.6-1.41.7
K content in liver0.20.21.1-1.10.70.7-0.50.5-0.1-0.30.2-0.20.10.30.40.3
Mg content in liver0.00.00.3-0.50.30.3-0.20.1-0.0-0.10.1-0.10.10.00.00.2
Mn content in liver0.91.01.4-0.51.21.2-1.01.0-1.0-1.00.9-0.9-1.10.90.9-1.1
Na content in liver0.00.00.20.30.10.10.20.10.4-0.0-0.10.10.3-0.1-0.10.3
Rb content in liver0.81.01.90.1-1.1-1.10.8-1.11.11.0-0.90.91.3-0.9-0.81.4
Se content in liver0.20.30.5-0.60.60.6-0.60.7-0.5-0.50.4-0.4-0.40.50.4-0.4
Sr content in liver0.00.00.10.30.00.00.1-0.1-0.00.2-0.10.1-0.1-0.1-0.1-0.1
Zn content in liver2.62.96.2-2.51.81.8-1.91.7-1.5-1.71.6-1.6-1.31.61.6-1.1
Bone: minimum diameter0.50.91.2-1.01.11.1-1.01.0-0.9-0.90.8-0.8-0.80.90.9-0.7
Time in familiar zone, hab. session 10.80.70.9-0.90.90.9-0.90.9-0.9-0.90.8-0.8-0.90.80.8-0.8
Time in novel zone, hab. session 10.40.30.60.3-0.7-0.70.5-0.80.50.7-0.60.50.6-0.5-0.50.6
Total zone transitions, hab. session 10.20.30.50.3-0.7-0.70.5-0.30.60.4-0.50.50.6-0.5-0.50.6
Total locomotion distance, hab. session 10.00.00.10.1-0.3-0.30.2-0.10.10.10.1-0.00.0-0.00.00.0
Locomotion velocity, hab. session 10.00.00.00.1-0.2-0.20.10.10.1-0.10.2-0.2-0.10.10.2-0.1
Time in familiar zone, hab. session 20.00.00.00.2-0.0-0.0-0.00.1-0.1-0.0-0.00.0-0.1-0.00.0-0.1
Time in novel zone, hab. session 20.10.10.20.2-0.4-0.40.3-0.50.20.4-0.30.30.2-0.3-0.30.2
Total zone transitions, hab. session 20.81.01.60.7-0.8-0.81.0-0.81.20.9-1.01.11.2-1.1-0.91.3
Total locomotion distance, hab. session 21.01.31.70.7-1.0-1.01.1-1.11.21.2-1.11.11.2-1.2-1.11.3
Locomotion velocity, hab. session 21.01.42.10.7-1.0-1.01.2-1.21.31.2-1.11.21.4-1.3-1.21.4
Novel to familiar place preference ratio0.00.00.10.00.30.30.1-0.00.10.10.00.10.0-0.10.10.0
Novelty place preference0.20.20.3-0.40.60.6-0.40.4-0.4-0.30.4-0.4-0.30.30.5-0.3
Time in novel zone, NPP test0.00.00.1-0.10.30.3-0.10.1-0.2-0.10.2-0.1-0.20.00.3-0.2
Total zone transitions, NPP test1.21.72.11.1-1.3-1.31.3-1.21.41.3-1.21.31.4-1.3-1.41.4
Total locomotion distance, NPP test1.72.42.81.5-1.6-1.61.6-1.51.61.5-1.41.51.5-1.5-1.71.4
Locomotion velocity, NPP test1.31.82.21.2-1.4-1.41.4-1.31.51.3-1.21.31.4-1.3-1.51.4
Intraocular pressure0.50.71.2-0.80.90.9-1.00.8-1.1-0.80.7-0.7-1.00.80.6-0.9
Delta distance traveled before/after self-admin0.20.20.4-0.2-0.5-0.50.3-0.60.50.5-0.40.30.6-0.3-0.20.6
Delta ambulatory time before/after self-admin0.60.70.80.6-0.8-0.80.9-0.90.90.9-0.90.90.9-0.9-0.40.9
Parametrial fat weight9.318.125.1-5.04.74.7-4.54.6-4.3-4.34.2-4.0-4.03.93.4-3.6
Pavlov. Cond. lever latency0.10.10.2-0.20.50.5-0.30.3-0.4-0.30.4-0.3-0.40.20.4-0.4
Pavlov. Cond. magazine entry latency0.60.81.00.7-0.8-0.80.8-1.00.80.9-1.00.90.9-0.9-0.80.9
Pavlov. Cond. change in total contacts0.10.10.40.30.10.1-0.20.1-0.4-0.20.1-0.2-0.50.2-0.1-0.6
Pavlov. Cond. index score0.30.30.40.5-0.7-0.70.5-0.70.60.6-0.70.50.5-0.4-0.60.6
Pavlov. Cond. latency score0.50.70.90.7-1.0-1.00.7-0.90.80.8-0.90.80.8-0.7-0.80.8
Pavlov. Cond. lever contacts0.20.20.30.3-0.5-0.50.3-0.50.50.4-0.50.40.5-0.2-0.50.5
Pavlov. Cond. magazine entry number0.81.01.3-0.81.11.1-0.91.1-0.9-1.01.1-0.9-0.90.91.1-0.9
Pavlov. Cond. intertrial magazine entries0.30.41.21.1-0.5-0.50.6-0.60.50.6-0.60.60.4-0.5-0.70.3
Pavlov. Cond. lever-magazine prob. diff.0.50.60.80.8-0.8-0.80.7-0.90.80.8-0.90.80.7-0.6-0.90.7
Pavlov. Cond. response bias1.21.41.71.2-1.2-1.21.2-1.31.21.2-1.31.11.1-1.1-1.21.1
Pavlov. Cond. lever latency0.40.51.2-0.50.90.9-0.71.1-0.8-0.80.6-0.5-0.80.50.5-0.7
Pavlov. Cond. magazine entry latency0.50.51.00.3-1.0-1.00.6-0.80.80.7-0.70.60.8-0.5-0.60.8
Pavlov. Cond. change in total contacts0.20.20.50.1-0.7-0.70.3-0.70.50.5-0.30.30.5-0.2-0.30.5
Pavlov. Cond. index score0.40.51.00.4-1.0-1.00.6-0.90.80.7-0.60.50.8-0.4-0.60.8
Pavlov. Cond. latency score0.60.81.20.5-1.1-1.10.8-1.01.00.8-0.70.70.9-0.6-0.70.9
Pavlov. Cond. lever contacts0.10.20.4-0.1-0.4-0.40.3-0.70.50.4-0.30.20.5-0.2-0.30.6
Pavlov. Cond. magazine entry number0.40.51.0-0.31.01.0-0.60.7-0.7-0.60.6-0.5-0.70.50.7-0.8
Pavlov. Cond. intertrial magazine entries1.82.33.0-1.01.71.7-1.51.5-1.7-1.51.4-1.4-1.71.41.4-1.7
Pavlov. Cond. lever-magazine prob. diff.0.40.50.80.3-0.9-0.90.6-0.90.80.7-0.60.50.7-0.4-0.50.7
Pavlov. Cond. response bias0.60.81.20.5-1.0-1.00.8-1.11.00.9-0.80.71.0-0.6-0.81.0
Time in closed arm before self-admin0.10.10.20.0-0.3-0.30.2-0.30.40.3-0.40.30.4-0.2-0.00.5
Time in closed arm after self-admin0.70.72.0-1.40.90.9-1.00.8-0.5-0.90.8-0.9-0.51.10.7-0.4
Time in open arm before self-admin0.70.71.2-0.60.70.7-0.90.7-0.9-0.80.9-0.9-1.11.00.3-1.1
Time in open arm after self-admin0.10.10.30.5-0.0-0.00.00.0-0.40.00.1-0.1-0.5-0.10.1-0.5
Bone: periosteal estimation0.30.60.80.9-0.6-0.60.8-0.70.80.7-0.90.80.8-0.8-0.50.8
Bone: periosteal perimeter0.10.20.50.2-0.0-0.00.4-0.30.50.4-0.50.50.7-0.60.00.7
Bone: post-yield work2.23.04.01.5-2.0-2.01.8-1.91.71.8-1.51.61.6-1.6-1.71.6
Progressive ratio test 1 active lever presses0.30.30.7-0.50.80.8-0.40.8-0.3-0.60.5-0.5-0.40.40.6-0.4
Progressive ratio test 1 breakpoint0.30.40.8-0.50.90.9-0.40.8-0.3-0.60.5-0.5-0.40.40.7-0.5
Progressive ratio test 1 inactive lever presses0.30.40.70.5-0.4-0.40.6-0.40.90.5-0.60.60.8-0.5-0.60.8
Progressive ratio test 2 active lever presses0.00.00.40.7-0.0-0.00.2-0.0-0.00.0-0.10.0-0.2-0.0-0.2-0.3
Progressive ratio test 2 breakpoint0.10.10.50.7-0.0-0.00.2-0.0-0.00.0-0.00.0-0.30.0-0.2-0.4
Progressive ratio test 2 inactive lever presses0.60.71.21.1-0.9-0.90.9-0.90.90.8-0.80.80.8-0.7-0.60.7
Incentive Sensitization - Responses0.30.31.20.70.10.1-0.30.2-0.7-0.30.4-0.4-0.90.50.4-1.1
Incentive Sensitization - Breakpoint0.60.61.90.40.40.4-0.60.5-1.0-0.60.7-0.7-1.20.80.6-1.4
Sum of active levers in priming session hrs 5-60.80.83.30.9-0.9-0.90.7-0.90.80.8-0.80.70.6-0.6-1.80.6
Progressive ratio0.40.50.70.4-0.7-0.70.6-0.60.70.7-0.70.60.7-0.6-0.80.8
Food seeking constrained by brief footshock4.96.08.62.9-2.6-2.62.5-2.42.42.5-2.42.42.3-2.3-2.22.1
Seeking ratio, punishment vs. effort0.40.51.01.0-0.8-0.80.8-0.70.70.7-0.60.70.7-0.7-0.20.5
Retroperitoneal fat weight12.541.270.9-8.46.86.8-7.06.5-6.5-6.36.1-6.1-5.76.05.6-5.1
Reaction time number correct0.10.20.30.6-0.3-0.30.5-0.50.30.5-0.40.50.4-0.60.20.2
Reaction time mean minus median0.40.51.2-0.40.60.6-0.60.6-1.1-0.50.7-0.5-1.00.40.8-1.0
Reaction time mean minus median AUC0.50.71.3-0.80.80.8-0.80.7-1.1-0.60.8-0.7-1.00.50.9-1.0
Reaction time num false alarms0.10.20.7-0.50.10.1-0.00.20.40.0-0.70.50.6-0.2-0.30.8
Reaction time num false alarms AUC0.10.10.4-0.70.50.5-0.30.60.0-0.3-0.40.20.30.00.10.4
Reaction time trials correct on left0.10.20.30.6-0.3-0.30.5-0.50.30.5-0.40.50.4-0.60.20.2
Reaction time trials on left0.10.10.30.5-0.2-0.20.5-0.50.20.5-0.40.40.3-0.50.20.2
Reaction time mean0.30.51.40.10.40.4-0.50.4-1.1-0.50.7-0.6-1.10.50.7-1.2
Reaction time mean AUC0.40.51.50.00.50.5-0.50.5-1.1-0.50.7-0.6-1.10.50.6-1.2
Median of all reaction times0.20.31.20.40.10.1-0.30.2-0.9-0.30.5-0.4-1.00.40.5-1.1
Reaction time omissions0.10.10.20.1-0.5-0.50.1-0.4-0.20.3-0.10.2-0.1-0.2-0.2-0.1
Reaction time false alarm rate0.30.41.2-1.10.90.9-0.81.1-0.3-0.80.1-0.3-0.10.60.10.1
Reaction time premature initiation rate0.50.71.20.4-0.8-0.80.9-1.01.00.9-0.70.81.1-0.9-0.41.1
Reaction time premature initiations0.81.11.50.8-1.0-1.01.2-1.21.11.1-0.91.11.2-1.2-0.31.2
Std. dev. reaction times0.30.41.1-0.20.70.7-0.50.5-1.1-0.40.5-0.4-0.90.30.6-1.0
Reaction time trials completed0.10.10.30.5-0.2-0.20.5-0.50.20.5-0.40.40.3-0.50.20.2
Reaction time trials AUC0.00.10.20.4-0.1-0.10.3-0.30.00.3-0.20.20.1-0.30.4-0.0
Run reversals in cocaine runway, females0.70.71.10.8-1.0-1.00.8-0.90.90.8-0.70.70.8-0.6-0.80.8
Run reversals in cocaine runway, males0.30.20.6-0.40.40.4-0.50.4-0.3-0.50.5-0.6-0.40.70.8-0.5
Latency to leave start box in cocaine runway7.88.410.32.7-2.6-2.62.9-2.52.92.8-3.23.23.2-3.1-2.73.1
Latency to leave start box in cocaine runway, F3.43.85.41.5-1.6-1.61.9-1.62.11.8-2.22.12.3-2.0-1.82.3
Latency to leave start box in cocaine runway, M5.95.76.82.6-2.2-2.22.4-2.12.32.4-2.52.62.4-2.5-2.52.3
Std. dev. time between licks in bursts0.10.20.20.3-0.5-0.50.4-0.50.20.5-0.50.40.4-0.40.20.4
Total sessions with >9 infusions0.91.01.5-0.31.21.2-0.81.1-0.8-1.11.1-1.0-1.11.00.4-1.2
Short access day 1 total inactive lever presses0.10.10.40.5-0.0-0.00.4-0.00.40.2-0.40.30.3-0.3-0.60.2
Short access day 10 total inactive lever presses1.92.12.60.8-1.5-1.51.4-1.61.41.5-1.41.51.6-1.5-1.31.6
Short access day 1 total infusions0.10.10.40.6-0.2-0.20.3-0.10.20.2-0.20.1-0.0-0.1-0.6-0.1
Short access day 10 total infusions0.10.10.50.7-0.1-0.10.3-0.10.30.1-0.20.30.2-0.3-0.40.1
Short access total infusions0.10.10.40.6-0.2-0.20.4-0.20.40.2-0.20.20.1-0.2-0.60.1
Short access day 1 locomotion0.10.10.30.40.50.5-0.10.5-0.2-0.30.0-0.1-0.40.2-0.2-0.5
Short access day 10 total locomotion0.10.10.40.50.20.2-0.10.2-0.3-0.30.2-0.2-0.50.30.1-0.6
Short access total locomotion0.40.41.00.30.80.8-0.40.8-0.6-0.80.5-0.5-0.90.5-0.0-1.0
One hour access (0.3 mA shock)1.82.14.82.2-1.5-1.51.6-1.51.31.5-1.41.41.1-1.4-1.50.9
Compulsive drug intake0.70.71.70.6-0.9-0.90.7-1.00.80.9-0.80.80.7-0.7-1.30.8
One hour access (shock baseline)0.10.11.01.0-0.2-0.20.5-0.10.30.2-0.30.30.1-0.30.0-0.0
Social response proportion0.80.81.9-0.41.31.3-0.81.4-0.8-1.10.7-0.7-0.80.70.7-0.8
Social responses0.00.10.2-0.20.20.2-0.10.5-0.2-0.3-0.00.0-0.00.00.40.0
Social time1.51.92.6-0.81.51.5-1.41.6-1.4-1.51.1-1.2-1.41.51.6-1.4
Soleus weight1.64.77.02.7-2.3-2.32.3-2.12.22.1-2.12.11.9-2.0-2.11.8
Bone: stiffness0.10.20.6-0.80.30.3-0.50.4-0.2-0.40.4-0.4-0.20.50.3-0.1
Tibialis anterior weight0.41.52.61.6-1.6-1.61.3-1.41.01.2-1.01.00.8-1.0-1.00.7
Time to tail flick, vehicle, before self-admin2.42.42.9-1.61.41.4-1.61.4-1.7-1.51.6-1.6-1.61.61.5-1.6
Time to tail flick, vehicle, after self-admin0.70.82.7-1.60.80.8-1.00.8-0.8-0.80.8-0.8-0.60.80.9-0.4
Time to tail flick, test, before self-admin0.20.20.40.20.50.5-0.20.4-0.3-0.40.3-0.4-0.50.40.1-0.7
Time to tail flick, test, after self-admin0.20.20.50.30.40.4-0.30.4-0.4-0.30.3-0.4-0.60.4-0.1-0.7
Delta time to tail flick, vehicle, before/after SA0.50.51.00.2-0.5-0.50.6-0.50.80.7-0.80.80.9-0.7-0.51.0
Delta time to tail flick, test, before/after SA0.50.41.21.1-0.6-0.60.7-0.50.50.6-0.60.60.4-0.7-0.80.4
Tibia length1.13.14.2-2.11.91.9-1.91.7-1.8-1.71.7-1.8-1.71.71.6-1.5
Ambulatory time before self-admin0.40.40.8-0.70.30.3-0.70.3-0.8-0.50.9-0.8-0.80.70.5-0.8
Ambulatory time after self-admin0.10.10.6-0.1-0.6-0.60.2-0.80.20.5-0.10.10.2-0.20.00.2
Bone: tissue strength1.91.82.2-1.21.21.2-1.41.3-1.5-1.31.4-1.4-1.51.31.3-1.5
Total heroin consumption1.41.63.82.0-1.4-1.41.4-1.30.91.4-1.01.10.7-1.3-1.60.5
Bone: trabecular number4.16.59.73.1-2.5-2.52.6-2.62.42.5-2.72.62.2-2.4-2.52.1
Bone: trabecular spacing3.64.65.5-2.32.02.0-2.12.2-2.1-2.22.3-2.3-2.12.12.2-2.0
Bone: trabecular thickness3.33.94.52.1-2.1-2.12.0-2.11.82.0-2.12.01.8-1.9-1.81.7
Bone: trabecular tissue density0.40.50.80.4-0.8-0.80.8-0.50.80.6-0.70.70.8-0.8-0.90.9
Water consumed over 24 hours1.82.13.01.4-1.7-1.71.4-1.61.31.5-1.31.31.3-1.3-1.61.2
Number of responses in last shaping day0.40.41.01.0-0.4-0.40.7-0.40.60.5-0.70.70.5-0.7-0.90.5