Sf3b1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Sf3b1 0.03 0.02 4.2e-03 0.02 0.02 0 0.02 6.6e-03 6.2e-03 1.1e-01 2.9e-03
2 PL alternative polyA NM_053426.1 0.33 0.18 0.0e+00 0.21 0.2 0.2 0.22 9.3e-23 2.7e-21 7.0e-22 3.0e-23
3 PL alternative polyA XM_017596654.2 0.31 0.16 0.0e+00 0.21 0.19 0.2 0.21 3.4e-22 9.9e-21 3.2e-21 2.1e-22
4 IL alternative polyA NM_053426.1 0.33 0.19 4.8e-06 0.18 0.15 0.14 0.14 5.0e-05 2.2e-04 3.5e-04 2.8e-04
5 IL alternative polyA XM_017596654.2 0.32 0.18 5.5e-06 0.16 0.15 0.14 0.14 1.5e-04 2.1e-04 3.5e-04 2.9e-04
6 BLA alternative polyA NM_053426.1 0.22 0.11 1.5e-11 0.17 0.19 0.19 0.19 2.8e-09 2.9e-10 1.4e-10 3.0e-10
7 BLA alternative polyA XM_017596654.2 0.21 0.11 1.4e-11 0.17 0.19 0.2 0.19 2.5e-09 2.1e-10 1.0e-10 2.3e-10
8 pVTA alternative polyA NM_053426.1 0.21 0.12 2.0e-06 0.14 0.09 0.11 0.12 1.9e-06 7.4e-05 2.0e-05 4.8e-06
9 pVTA alternative polyA XM_017596654.2 0.21 0.12 2.6e-06 0.13 0.09 0.1 0.12 2.8e-06 1.3e-04 3.1e-05 7.2e-06
10 Brain isoform ratio XM_017596654.2 0.06 0.04 5.7e-05 0.05 0.03 0.03 0.04 1.8e-05 6.0e-04 6.3e-04 1.7e-04
11 Brain alternative polyA XM_017596654.2 0.35 0.14 0.0e+00 0.27 0.27 0.27 0.27 3.8e-25 1.1e-24 7.6e-25 5.7e-25
12 Brain alternative polyA NM_053426.1 0.35 0.14 0.0e+00 0.27 0.26 0.26 0.27 6.1e-25 1.6e-24 1.2e-24 8.4e-25
13 NAcc alternative polyA NM_053426.1 0.16 0.08 6.1e-16 0.13 0.12 0.12 0.13 5.1e-15 8.2e-14 2.0e-13 8.9e-15
14 NAcc alternative polyA XM_017596654.2 0.16 0.09 3.3e-15 0.12 0.12 0.11 0.12 2.4e-14 3.5e-13 5.8e-13 5.3e-14
15 Adipose alternative polyA NM_053426.1 0.05 0.04 3.3e-05 0.03 0.03 0.03 0.03 9.3e-05 4.6e-04 1.2e-04 2.2e-04
16 Adipose alternative polyA XM_017596654.2 0.05 0.04 1.6e-05 0.04 0.03 0.04 0.03 6.0e-05 2.6e-04 9.0e-05 1.5e-04
17 PL isoform ratio NM_053426.1 0.04 0.03 6.4e-04 0.02 0.01 0.01 0.02 9.5e-04 1.6e-02 1.7e-02 4.9e-03
18 RMTg alternative polyA NM_053426.1 0.18 0.13 8.8e-03 0.05 0 0.01 0 1.7e-02 2.3e-01 1.7e-01 3.0e-01
19 RMTg alternative polyA XM_017596654.2 0.18 0.13 8.5e-03 0.06 0.01 -0 0.01 1.3e-02 1.3e-01 4.3e-01 1.3e-01
20 OFC alternative polyA XM_017596654.2 0.33 0.21 2.5e-04 0.05 0.1 0.08 0.07 2.8e-02 2.8e-03 4.9e-03 7.6e-03
21 OFC alternative polyA NM_053426.1 0.35 0.21 1.3e-04 0.05 0.1 0.09 0.08 2.3e-02 2.1e-03 3.5e-03 6.3e-03
22 LHb alternative polyA XM_017596654.2 0.29 0.17 5.2e-06 0.12 0.14 0.09 0.15 1.1e-03 4.2e-04 3.1e-03 2.6e-04
23 LHb alternative polyA NM_053426.1 0.31 0.17 2.0e-06 0.13 0.15 0.1 0.15 6.1e-04 2.6e-04 2.2e-03 1.8e-04
24 PL isoform ratio XM_017596654.2 0.04 0.03 2.4e-04 0.02 0.02 0.02 0.02 2.1e-03 3.8e-03 2.1e-03 2.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density8.013.414.73.83.8-3.8-3.23.2-3.63.6-3.83.83.83.8-3.8-3.73.7-3.83.8-3.8-3.83.8-3.73.7-3.33.33.3
Area under the delay curve0.00.00.2-0.2-0.20.20.2-0.20.2-0.20.0-0.0-0.0-0.00.00.1-0.10.2-0.20.20.2-0.20.1-0.10.4-0.40.1
BMI with tail4.113.215.6-3.9-3.93.93.2-3.23.7-3.83.6-3.6-3.7-3.63.63.8-3.83.6-3.63.63.6-3.63.7-3.73.7-3.7-2.7
BMI without tail0.10.30.9-0.5-0.50.50.9-0.90.4-0.40.4-0.4-0.4-0.50.50.6-0.60.5-0.50.50.5-0.50.2-0.2-0.10.1-1.0
Body weight0.73.14.51.81.8-1.8-2.12.1-2.02.0-1.81.81.71.7-1.7-1.61.6-1.61.6-1.6-1.61.6-1.81.8-1.91.91.3
Weight adjusted by age1.21.31.71.31.2-1.2-1.11.1-1.11.1-1.11.11.21.1-1.1-1.31.3-1.31.3-1.3-1.31.3-0.90.9-0.80.81.3
Bone surface7.613.414.83.93.8-3.8-3.23.2-3.63.6-3.83.83.83.8-3.8-3.73.7-3.83.8-3.8-3.83.8-3.73.7-3.33.33.4
Bone volume8.414.315.74.04.0-4.0-3.33.3-3.73.7-3.93.93.93.9-3.9-3.93.9-3.93.9-3.9-3.93.9-3.73.7-3.33.33.6
Breakpoint value in progressive ratio session0.00.00.2-0.1-0.10.1-0.50.5-0.10.00.1-0.1-0.1-0.10.10.1-0.10.0-0.00.00.0-0.00.2-0.20.2-0.20.4
Number of licking bursts0.50.61.2-0.8-0.80.80.4-0.40.9-0.90.7-0.7-0.7-0.70.70.7-0.70.7-0.70.70.7-0.70.9-0.91.1-1.1-0.3
Context. condit. distance diff. score1.82.13.0-1.5-1.51.51.4-1.41.4-1.41.5-1.5-1.5-1.51.51.6-1.61.6-1.61.61.6-1.61.3-1.30.9-0.9-1.7
Locomotion velocity, session 10.70.73.5-0.7-0.70.71.9-1.91.0-0.90.6-0.6-0.6-0.60.60.6-0.60.6-0.60.60.6-0.60.6-0.60.8-0.8-1.1
Locomotion distance, session 10.10.21.1-0.3-0.30.31.0-1.00.5-0.40.3-0.3-0.3-0.30.30.3-0.30.1-0.10.10.1-0.10.3-0.3-0.00.0-0.8
Locomotion velocity, session 20.30.42.5-0.4-0.40.41.6-1.60.8-0.70.3-0.3-0.3-0.30.30.3-0.30.3-0.30.30.3-0.30.4-0.40.6-0.6-0.6
Locomotion distance, session 20.10.10.4-0.3-0.30.30.6-0.60.4-0.40.3-0.3-0.3-0.30.30.3-0.30.3-0.30.30.3-0.30.3-0.30.2-0.2-0.5
Locomotion velocity, session 30.10.10.60.10.1-0.00.3-0.3-0.10.20.1-0.1-0.1-0.10.10.0-0.00.0-0.00.00.0-0.0-0.10.1-0.80.8-0.7
Locomotion distance, session 30.00.00.2-0.2-0.20.20.3-0.30.1-0.10.3-0.3-0.2-0.20.20.2-0.20.1-0.10.10.1-0.10.2-0.2-0.10.1-0.4
Stereotopy head waving bouts, day 31.61.93.4-1.3-1.31.31.6-1.61.4-1.31.4-1.4-1.4-1.41.41.4-1.41.3-1.31.31.3-1.31.2-1.20.7-0.7-1.9
Stereotopy head waving duration, day 30.30.31.4-0.4-0.50.50.8-0.80.5-0.50.6-0.6-0.6-0.60.60.5-0.50.5-0.50.50.5-0.50.4-0.4-0.20.2-1.2
Locomotion velocity, session 70.30.42.7-0.4-0.40.31.7-1.70.7-0.70.2-0.2-0.3-0.30.30.3-0.30.2-0.20.20.2-0.20.3-0.30.6-0.6-0.6
Locomotion distance, session 70.00.00.1-0.2-0.10.10.4-0.40.2-0.20.0-0.0-0.1-0.10.10.1-0.10.2-0.20.20.2-0.20.1-0.10.3-0.3-0.0
Stereotopy head waving bouts, day 70.40.40.60.80.7-0.7-0.00.0-0.50.6-0.70.70.70.7-0.7-0.80.8-0.80.8-0.8-0.80.8-0.70.7-0.60.60.4
Stereotopy head waving duration, day 70.20.20.30.50.5-0.50.4-0.4-0.20.3-0.40.40.40.4-0.4-0.50.5-0.50.5-0.5-0.50.5-0.50.5-0.60.6-0.2
Locomotion velocity, session 80.20.21.4-0.3-0.30.31.2-1.20.6-0.60.2-0.2-0.2-0.20.20.2-0.20.2-0.20.20.2-0.20.4-0.40.8-0.8-0.1
Locomotion distance, session 81.21.82.9-1.4-1.41.41.7-1.71.3-1.31.4-1.4-1.4-1.41.41.4-1.41.3-1.31.31.3-1.31.2-1.20.7-0.7-1.7
Degree of sensitization distance0.10.10.60.20.3-0.3-0.40.4-0.10.2-0.50.50.40.4-0.4-0.30.3-0.20.2-0.2-0.20.2-0.20.20.3-0.30.8
Degree of sensitization stereotypy0.50.60.80.80.8-0.8-0.30.3-0.60.6-0.80.80.80.8-0.8-0.90.9-0.90.9-0.9-0.90.9-0.70.7-0.40.40.8
Conditioned locomotion1.11.34.11.11.1-1.1-2.02.0-1.31.2-1.01.01.01.0-1.0-1.01.0-1.01.0-1.0-1.01.0-0.90.9-0.90.91.3
Cocaine response after cond. corrected2.52.86.01.71.7-1.7-1.71.7-1.61.5-1.81.81.81.8-1.8-1.81.8-1.71.7-1.7-1.71.7-1.41.4-0.70.72.5
Cocaine response after cond. not corrected4.04.47.52.22.2-2.2-1.81.8-2.02.0-2.22.22.22.2-2.2-2.22.2-2.22.2-2.2-2.22.2-1.91.9-1.21.22.7
Cocaine response before conditioning0.00.10.3-0.1-0.20.20.5-0.50.2-0.20.2-0.2-0.2-0.20.20.2-0.20.1-0.10.10.1-0.10.1-0.1-0.20.2-0.5
Saline control response0.30.40.8-0.7-0.70.70.3-0.30.5-0.50.7-0.7-0.7-0.70.70.7-0.70.7-0.70.70.7-0.70.6-0.60.2-0.2-0.9
Bone: connectivity density4.16.57.32.72.7-2.7-2.12.1-2.52.5-2.72.72.72.7-2.7-2.62.6-2.72.7-2.7-2.72.7-2.62.6-2.22.22.4
Bone: cortical apparent density8.511.212.9-3.6-3.63.62.7-2.73.3-3.43.4-3.4-3.4-3.43.43.4-3.43.4-3.43.43.4-3.43.5-3.53.4-3.4-2.7
Bone: cortical area0.20.30.40.60.6-0.6-0.60.6-0.50.5-0.50.50.50.5-0.5-0.60.6-0.60.6-0.6-0.60.6-0.50.5-0.60.60.5
Bone: cortical porosity5.15.67.42.52.4-2.4-2.02.0-2.52.4-2.32.32.32.3-2.3-2.32.3-2.42.4-2.4-2.42.4-2.42.4-2.72.71.6
Bone: cortical porosity7.37.99.52.92.9-2.9-2.62.6-2.92.9-2.82.82.72.7-2.7-2.72.7-2.92.9-2.9-2.92.9-2.92.9-3.13.12.1
Bone: cortical thickness1.52.42.8-1.7-1.71.71.2-1.21.6-1.61.6-1.6-1.6-1.61.61.6-1.61.5-1.51.51.5-1.51.7-1.71.5-1.5-1.3
Bone: cortical thickness0.91.12.3-1.1-1.11.10.9-0.91.2-1.21.0-1.0-1.0-1.01.01.0-1.00.9-0.90.90.9-0.91.2-1.21.5-1.5-0.3
Bone: cortical tissue density8.611.413.1-3.6-3.63.62.7-2.73.4-3.43.4-3.4-3.4-3.43.43.4-3.43.5-3.53.53.5-3.53.5-3.53.4-3.4-2.7
Condit. Reinf. active minus inactive responses0.30.31.60.30.4-0.4-1.11.1-0.40.4-0.40.40.40.4-0.4-0.40.4-0.50.5-0.5-0.50.5-0.20.20.3-0.31.3
Condit. Reinf. active-inactive response ratio0.10.10.50.20.3-0.3-0.30.3-0.10.1-0.30.30.30.3-0.3-0.30.3-0.30.3-0.3-0.30.3-0.10.10.2-0.20.7
Condit. Reinf. active responses1.01.23.70.91.0-1.0-1.91.9-1.01.0-1.01.01.01.0-1.0-1.01.0-1.11.1-1.1-1.11.1-0.70.7-0.20.21.9
Condit. Reinf. inactive responses0.30.41.60.50.5-0.5-1.31.3-0.60.6-0.60.60.60.6-0.6-0.50.5-0.60.6-0.6-0.60.6-0.40.4-0.10.11.1
Incentive salience index mean0.60.73.10.60.7-0.7-1.51.5-0.70.6-0.70.70.80.8-0.8-0.80.8-0.80.8-0.8-0.80.8-0.40.40.2-0.21.8
Condit. Reinf. lever presses0.60.71.90.80.8-0.8-1.41.4-0.80.8-0.80.80.80.8-0.8-0.80.8-0.80.8-0.8-0.80.8-0.60.6-0.20.21.4
Condit. Reinf. active minus inactive responses4.15.19.62.22.2-2.2-3.03.0-2.22.2-2.32.32.32.3-2.3-2.32.3-2.22.2-2.2-2.22.2-1.91.9-1.31.33.1
Condit. Reinf. active-inactive response ratio1.01.13.80.90.9-0.9-1.61.6-0.90.9-1.01.01.01.0-1.0-1.01.0-1.01.0-1.0-1.01.0-0.70.7-0.10.12.0
Condit. Reinf. active responses2.33.27.41.71.7-1.7-2.62.6-1.61.6-1.81.81.81.8-1.8-1.81.8-1.71.7-1.7-1.71.7-1.41.4-0.80.82.7
Condit. Reinf. inactive responses0.30.40.60.60.6-0.6-0.60.6-0.50.5-0.70.70.70.7-0.7-0.60.6-0.70.7-0.7-0.70.7-0.60.6-0.40.40.7
Condit. Reinf. lever presses0.20.21.4-0.4-0.30.3-0.30.30.5-0.50.1-0.1-0.1-0.10.10.2-0.20.2-0.20.20.2-0.20.5-0.51.2-1.20.9
Condit. Reinf. lever reinforcers received2.23.17.81.61.7-1.7-2.52.5-1.61.5-1.81.81.81.8-1.8-1.71.7-1.71.7-1.7-1.71.7-1.31.4-0.60.62.8
Conditioned reinforcement - actives0.10.10.5-0.0-0.10.10.4-0.4-0.00.00.2-0.2-0.1-0.10.10.1-0.10.2-0.20.20.2-0.2-0.10.1-0.40.4-0.7
Conditioned reinforcement - inactives0.10.10.20.30.3-0.30.0-0.0-0.20.2-0.40.40.20.3-0.3-0.20.2-0.10.1-0.1-0.10.1-0.40.4-0.30.3-0.0
Conditioned locomotion0.70.81.1-0.9-0.90.9-0.00.00.8-0.80.9-0.9-0.9-0.90.90.9-0.91.1-1.11.11.1-1.11.0-1.01.1-1.1-0.4
Patch foraging indifference point 0 sec0.30.52.4-0.6-0.60.60.5-0.51.0-0.90.5-0.5-0.4-0.50.50.4-0.40.4-0.40.40.4-0.40.9-0.91.5-1.50.3
Patch foraging indifference point AUC0.10.10.20.40.4-0.4-0.30.3-0.30.4-0.40.40.40.4-0.4-0.40.4-0.30.3-0.3-0.30.3-0.50.5-0.30.30.4
Delay disc. indifference point, 0s delay1.92.02.5-1.5-1.51.51.3-1.31.6-1.61.4-1.4-1.4-1.41.41.4-1.41.4-1.41.41.4-1.41.5-1.51.6-1.6-1.1
Delay disc. indifference point, 16s delay0.00.00.00.00.1-0.10.1-0.10.1-0.0-0.10.10.10.1-0.1-0.10.1-0.10.1-0.1-0.10.1-0.00.00.2-0.20.2
Delay disc. indifference point, 2s delay1.01.13.1-1.1-1.11.10.2-0.21.0-1.10.9-0.9-0.9-0.90.91.0-1.01.0-1.01.01.0-1.01.2-1.21.8-1.80.1
Delay disc. indifference point, 24s delay0.40.40.7-0.6-0.60.60.7-0.70.6-0.60.6-0.6-0.6-0.60.60.7-0.70.6-0.60.60.6-0.60.6-0.60.4-0.4-0.8
Delay disc. indifference point, 4s delay0.70.70.9-0.9-0.90.90.9-0.90.9-0.90.8-0.8-0.8-0.80.80.8-0.80.7-0.70.70.7-0.70.9-0.90.9-0.9-0.7
Delay disc. indifference point, 8s delay0.40.40.60.70.7-0.7-0.10.1-0.60.6-0.80.80.70.7-0.7-0.60.6-0.60.6-0.6-0.60.6-0.80.8-0.60.60.5
Indifference point function ln k0.91.23.0-1.1-1.11.10.9-0.91.3-1.31.0-1.0-1.0-1.01.01.0-1.00.9-0.90.90.9-0.91.3-1.31.7-1.7-0.3
Indifference point function log k0.91.23.0-1.1-1.11.10.9-0.91.3-1.31.0-1.0-1.0-1.01.01.0-1.00.9-0.90.90.9-0.91.3-1.31.7-1.7-0.3
Patch foraging total patch changes 0 sec0.50.82.8-0.8-0.80.80.6-0.61.1-1.10.7-0.7-0.6-0.70.70.6-0.60.6-0.60.60.6-0.61.1-1.11.7-1.70.1
Patch foraging total patch changes 12 sec0.20.20.9-0.4-0.40.4-0.20.20.5-0.50.3-0.3-0.3-0.30.30.2-0.20.3-0.30.30.3-0.30.6-0.61.0-1.00.4
Patch foraging total patch changes 18 sec1.51.93.8-1.3-1.31.31.9-1.91.6-1.61.3-1.3-1.2-1.21.21.2-1.21.2-1.21.21.2-1.21.3-1.31.7-1.7-0.9
Patch foraging total patch changes 24 sec0.00.00.00.10.1-0.1-0.00.0-0.00.1-0.10.10.20.1-0.1-0.10.1-0.10.1-0.1-0.10.1-0.10.1-0.00.00.1
Patch foraging total patch changes 6 sec0.10.10.5-0.3-0.20.20.4-0.40.6-0.50.2-0.2-0.2-0.20.20.1-0.10.1-0.10.10.1-0.10.4-0.40.7-0.70.2
Patch foraging time to switch 0 sec0.10.10.70.30.2-0.20.4-0.4-0.20.3-0.10.10.10.1-0.1-0.10.1-0.10.1-0.1-0.10.1-0.40.4-0.80.8-0.7
Patch foraging water rate 0 sec0.10.10.50.10.1-0.1-0.70.7-0.20.2-0.20.20.10.2-0.2-0.10.1-0.20.2-0.2-0.20.2-0.00.00.1-0.10.7
Patch foraging water rate 12 sec0.30.42.1-0.6-0.50.5-0.10.10.7-0.70.4-0.4-0.3-0.40.40.4-0.40.3-0.30.30.3-0.30.8-0.81.5-1.50.7
Patch foraging water rate 18 sec0.30.42.20.30.4-0.4-1.51.5-0.40.4-0.40.40.50.4-0.4-0.40.4-0.50.5-0.5-0.50.5-0.10.10.0-0.01.2
Patch foraging water rate 24 sec0.10.10.30.20.2-0.20.0-0.0-0.30.3-0.20.20.10.1-0.1-0.20.2-0.30.3-0.3-0.30.3-0.20.2-0.60.6-0.1
Patch foraging water rate 6 sec0.10.10.5-0.3-0.30.3-0.70.70.0-0.10.3-0.3-0.2-0.30.30.3-0.30.2-0.20.20.2-0.20.4-0.40.3-0.30.4
Seeking ratio, delayed vs. immediate footshock1.92.22.81.61.5-1.5-1.71.7-1.51.5-1.41.41.51.5-1.5-1.51.5-1.61.6-1.6-1.61.6-1.41.4-1.31.31.4
Distance traveled before self-admin2.52.63.31.61.6-1.6-1.81.8-1.71.6-1.81.81.71.7-1.7-1.61.6-1.61.6-1.6-1.61.6-1.61.6-1.21.21.8
Distance traveled after self-admin0.60.71.1-1.0-0.90.9-0.00.00.7-0.70.8-0.8-0.8-0.80.80.9-0.90.9-0.90.90.9-0.90.9-0.91.1-1.1-0.3
Extensor digitorum longus weight2.28.610.9-3.0-3.03.03.0-3.02.9-2.93.0-3.0-3.0-3.03.03.0-3.03.0-3.03.03.0-3.02.7-2.72.1-2.1-3.3
Bone: elastic displacement0.40.51.1-0.7-0.70.70.0-0.00.7-0.70.7-0.7-0.7-0.70.70.6-0.60.6-0.60.60.6-0.60.9-0.91.1-1.10.1
Bone: elastic work1.21.52.11.21.2-1.2-1.41.4-1.21.2-1.11.11.21.2-1.2-1.21.2-1.31.3-1.3-1.31.3-1.11.1-0.90.91.5
Bone: endosteal estimation5.612.213.53.73.6-3.6-3.43.4-3.53.5-3.53.53.53.5-3.5-3.53.5-3.63.6-3.6-3.63.6-3.43.4-3.23.23.3
Bone: endosteal perimeter5.110.612.03.53.4-3.4-2.92.9-3.33.3-3.33.33.33.3-3.3-3.33.3-3.33.3-3.3-3.33.3-3.33.3-3.13.12.9
Epididymis fat weight1.12.74.21.71.6-1.6-2.12.1-2.01.9-1.51.51.61.5-1.5-1.41.4-1.41.4-1.4-1.41.4-1.71.7-2.02.01.1
Delta time in closed arm before/after self-admin0.40.41.3-0.5-0.50.51.1-1.10.6-0.50.5-0.5-0.6-0.60.60.6-0.60.5-0.50.50.5-0.50.3-0.3-0.10.1-1.0
Delta time in open arm before/after self-admin6.96.77.92.72.7-2.7-2.42.4-2.52.5-2.72.72.72.7-2.7-2.72.7-2.72.7-2.7-2.72.7-2.52.5-1.81.82.8
Diff in mean of infusions in LGA sessions0.40.51.10.70.7-0.7-0.60.6-0.60.6-0.70.70.60.6-0.6-0.80.8-0.90.9-0.9-0.90.9-0.50.5-0.30.31.0
Delay discount exponential model param0.00.00.20.20.2-0.2-0.10.1-0.20.2-0.00.00.00.0-0.0-0.10.1-0.20.2-0.2-0.20.2-0.10.1-0.40.4-0.2
Extinction: sum of active levers before priming0.90.92.31.00.9-0.9-1.51.5-1.01.0-0.80.80.80.8-0.8-0.90.9-0.90.9-0.9-0.90.9-0.70.7-0.90.91.0
Active lever presses in extinction session 60.30.31.20.50.5-0.5-1.11.1-0.70.6-0.50.50.60.6-0.6-0.50.5-0.40.4-0.4-0.40.4-0.40.4-0.00.00.9
Bone: final force1.32.23.71.51.4-1.4-1.91.9-1.61.6-1.31.31.31.3-1.3-1.31.3-1.41.4-1.4-1.41.4-1.41.4-1.91.91.0
Bone: final moment0.91.53.01.21.1-1.1-1.71.7-1.41.3-1.01.01.01.0-1.0-1.01.0-1.11.1-1.1-1.11.1-1.11.1-1.61.60.8
Food consumed during 24 hour testing period0.00.00.10.10.1-0.1-0.40.4-0.20.2-0.10.10.10.1-0.1-0.10.1-0.10.1-0.1-0.10.1-0.20.2-0.30.30.0
Glucose0.91.42.8-1.2-1.21.20.3-0.30.8-0.91.3-1.3-1.3-1.31.31.3-1.31.4-1.41.41.4-1.41.0-1.00.3-0.3-1.7
Heart weight0.00.10.3-0.2-0.20.2-0.30.30.1-0.10.1-0.1-0.0-0.10.10.2-0.20.1-0.10.10.1-0.10.3-0.30.5-0.50.5
Delay discount hyperbolic model param0.10.10.40.40.4-0.4-0.30.3-0.40.4-0.20.20.20.2-0.2-0.40.4-0.40.4-0.4-0.40.4-0.40.3-0.70.70.0
Intermittent access intake day 1-15 change0.70.71.1-0.9-0.90.90.3-0.30.7-0.71.1-1.1-0.9-1.01.00.9-0.90.9-0.90.90.9-0.90.9-0.90.4-0.4-0.9
Intermittent access intake escalation0.60.60.9-0.8-0.80.80.2-0.20.6-0.60.9-0.9-0.8-0.90.90.8-0.80.8-0.80.80.8-0.80.8-0.80.4-0.4-0.8
Intermittent access intake escalation 20.00.00.30.10.1-0.1-0.50.5-0.20.20.0-0.00.10.1-0.1-0.10.1-0.20.2-0.2-0.20.2-0.0-0.0-0.40.40.1
Intermitt. access day 1 inactive lever presses2.12.33.1-1.7-1.61.61.0-1.01.4-1.41.4-1.4-1.7-1.61.61.7-1.71.8-1.81.81.8-1.81.3-1.30.9-0.9-1.5
Intermitt. access day 15 inactive lever presses0.10.10.2-0.4-0.40.40.3-0.30.3-0.30.3-0.3-0.4-0.40.40.4-0.40.4-0.40.40.4-0.40.3-0.30.2-0.2-0.3
Intermitt. access escalation Index0.20.21.20.20.2-0.2-0.70.7-0.60.5-0.10.10.10.1-0.1-0.10.1-0.20.2-0.2-0.20.2-0.40.4-1.11.1-0.2
Intermittent access day 1 total infusions0.50.62.20.70.7-0.7-1.51.5-0.90.9-0.60.60.60.6-0.6-0.60.6-0.50.5-0.5-0.50.5-0.60.6-0.70.70.7
Intermittent access day 15 total infusions0.10.21.3-0.1-0.10.1-1.11.1-0.30.30.2-0.2-0.2-0.20.20.1-0.10.2-0.20.20.2-0.20.1-0.1-0.40.4-0.1
Intermittent access terminal intake (last 3 days)0.10.11.1-0.2-0.20.2-1.01.0-0.10.10.3-0.3-0.2-0.20.20.2-0.20.3-0.30.30.3-0.30.3-0.3-0.10.1-0.1
Intermittent access total infusions0.30.42.40.40.4-0.4-1.51.5-0.70.7-0.30.30.30.3-0.3-0.30.3-0.20.2-0.2-0.20.2-0.40.4-0.70.70.4
Intermittent access day 1 locomotion0.10.10.2-0.3-0.30.3-0.40.40.1-0.20.2-0.2-0.3-0.30.30.3-0.30.4-0.40.40.4-0.40.2-0.20.3-0.3-0.1
Intermittent access day 15 total locomotion0.40.51.70.70.7-0.7-1.31.3-0.80.8-0.60.60.60.6-0.6-0.70.7-0.50.5-0.5-0.50.5-0.50.5-0.40.40.6
Intermittent access total locomotion0.10.10.90.10.1-0.1-0.90.9-0.30.3-0.10.10.10.1-0.1-0.10.10.1-0.10.10.1-0.1-0.10.1-0.20.20.2
Intermittent access standard deviation0.80.81.2-1.0-1.01.0-0.20.20.6-0.61.1-1.1-1.0-1.01.01.0-1.01.1-1.11.11.1-1.11.0-1.00.5-0.5-0.6
Left kidney weight0.20.40.80.60.6-0.6-0.90.9-0.60.6-0.70.70.70.7-0.7-0.60.6-0.60.6-0.6-0.60.6-0.60.6-0.30.30.7
Right kidney weight0.20.60.80.80.8-0.8-0.80.8-0.70.7-0.80.80.80.8-0.8-0.80.8-0.90.9-0.9-0.90.9-0.60.6-0.50.50.9
Cocaine induced anxiety0.20.20.3-0.4-0.50.50.1-0.10.3-0.30.6-0.6-0.4-0.50.50.4-0.40.5-0.50.50.5-0.50.5-0.50.2-0.2-0.3
Post-drug Anxiety0.00.00.1-0.2-0.10.1-0.10.10.2-0.2-0.00.0-0.1-0.10.10.1-0.10.1-0.10.10.1-0.10.1-0.10.3-0.30.3
Baseline Anxiety0.40.40.70.60.7-0.7-0.40.4-0.50.5-0.80.80.70.7-0.7-0.70.7-0.70.7-0.7-0.70.7-0.70.7-0.30.30.7
Tail length10.331.239.86.05.9-5.9-5.05.0-6.06.0-5.55.55.65.5-5.5-5.55.5-5.45.4-5.4-5.45.4-5.95.8-6.36.33.6
Length with tail11.040.445.86.76.7-6.6-6.06.0-6.86.7-6.46.46.46.3-6.3-6.36.3-6.26.2-6.2-6.26.2-6.66.6-6.86.84.5
Length without tail1.22.74.41.71.7-1.7-2.12.1-1.71.7-1.71.71.51.6-1.6-1.61.6-1.61.6-1.6-1.61.6-1.61.6-1.41.41.6
Times rat made contact with spout0.00.00.20.00.0-0.00.2-0.2-0.10.10.0-0.0-0.0-0.00.00.0-0.00.0-0.00.00.0-0.0-0.10.1-0.40.4-0.4
Lifetime Intake0.10.11.00.00.0-0.0-1.01.0-0.30.30.1-0.1-0.1-0.10.10.1-0.10.1-0.10.10.1-0.1-0.10.0-0.50.5-0.1
Liver weight, left1.93.03.31.81.8-1.8-1.41.4-1.71.7-1.81.81.81.8-1.8-1.81.8-1.81.8-1.8-1.81.8-1.71.7-1.61.61.5
Liver weight, right1.42.32.61.61.6-1.6-1.31.3-1.41.5-1.61.61.61.6-1.6-1.51.5-1.61.6-1.6-1.61.6-1.61.6-1.41.41.2
Locomotor activity0.10.20.50.30.3-0.3-0.70.7-0.40.4-0.40.40.30.4-0.4-0.30.3-0.40.4-0.4-0.40.4-0.30.3-0.40.40.5
Locomotor testing distance0.00.10.4-0.00.0-0.0-0.50.50.0-0.0-0.10.10.00.1-0.1-0.10.1-0.10.1-0.1-0.10.10.1-0.10.3-0.30.7
Locomotor testing rearing0.20.30.50.50.5-0.5-0.70.7-0.60.6-0.60.60.40.5-0.5-0.50.5-0.40.4-0.4-0.40.4-0.50.5-0.60.60.5
Locomotion in novel chamber1.72.12.6-1.6-1.61.61.0-1.01.5-1.51.5-1.5-1.5-1.51.51.6-1.61.5-1.51.51.5-1.51.6-1.51.5-1.5-0.9
Locomotion in novel chamber post-restriction1.31.62.1-1.2-1.21.21.5-1.51.3-1.31.2-1.2-1.2-1.21.21.2-1.21.3-1.31.31.3-1.31.2-1.21.2-1.2-1.2
Fecal boli incidents, locomotor time 13.74.04.92.12.2-2.2-1.31.3-1.91.9-2.12.12.12.1-2.1-2.22.2-2.22.2-2.2-2.22.2-1.91.9-1.41.42.2
Change in fecal boli incidents, locomotor task0.30.30.4-0.5-0.50.50.0-0.00.5-0.50.6-0.6-0.6-0.60.60.5-0.50.5-0.50.50.5-0.50.6-0.60.3-0.3-0.5
Time >=10cm from walls, locomotor time 10.60.62.30.70.8-0.80.1-0.1-0.30.4-1.01.01.01.0-1.0-0.90.9-0.80.8-0.8-0.80.8-0.60.60.4-0.41.5
Bouts of movement, locomotor time 10.20.20.40.50.5-0.5-0.30.3-0.20.3-0.50.50.50.5-0.5-0.60.6-0.60.6-0.6-0.60.6-0.40.4-0.20.20.6
Total resting periods, locomotor time 10.10.10.3-0.2-0.20.20.4-0.40.5-0.40.2-0.2-0.2-0.20.20.1-0.10.1-0.10.10.1-0.10.3-0.30.6-0.60.1
Rest time, locomotor task time 10.20.30.4-0.5-0.50.50.3-0.30.5-0.50.6-0.6-0.6-0.60.60.5-0.50.5-0.50.50.5-0.50.6-0.60.3-0.3-0.5
Distance moved, locomotor task time 10.20.30.40.50.6-0.6-0.40.4-0.30.4-0.60.60.60.6-0.6-0.60.6-0.60.6-0.6-0.60.6-0.50.5-0.10.10.6
Vertical activity count, locomotor time 10.20.20.6-0.4-0.40.40.8-0.80.3-0.40.4-0.4-0.4-0.40.40.4-0.40.4-0.40.40.4-0.40.2-0.20.1-0.1-0.7
Time >=10cm from walls, locomotor time 21.41.54.41.21.2-1.2-1.31.3-1.00.9-1.31.31.31.3-1.3-1.31.3-1.31.3-1.3-1.31.3-0.90.9-0.00.02.1
Bouts of movement, locomotor time 20.50.51.6-0.8-0.70.70.4-0.40.9-0.90.6-0.6-0.6-0.60.60.6-0.60.6-0.60.60.6-0.60.8-0.81.3-1.30.0
Total resting periods, locomotor time 20.50.51.7-0.8-0.70.70.4-0.40.9-0.90.6-0.6-0.6-0.60.60.6-0.60.6-0.60.60.6-0.60.9-0.91.3-1.30.0
Rest time, locomotor task time 20.20.20.5-0.4-0.40.40.6-0.60.3-0.30.5-0.5-0.5-0.50.50.4-0.40.4-0.40.40.4-0.40.3-0.30.0-0.0-0.7
Distance moved, locomotor task time 20.30.30.70.50.5-0.5-0.50.5-0.30.4-0.70.70.70.7-0.7-0.60.6-0.60.6-0.6-0.60.6-0.50.50.1-0.10.8
Vertical activity count, locomotor time 20.30.30.5-0.7-0.60.60.4-0.40.6-0.60.5-0.5-0.5-0.50.50.6-0.60.5-0.50.50.5-0.50.6-0.60.7-0.7-0.3
Light reinforcement 13.05.56.9-2.6-2.62.60.8-0.82.2-2.22.6-2.6-2.5-2.62.62.5-2.52.4-2.42.42.4-2.42.6-2.62.1-2.1-1.9
Light reinforcement 20.20.21.3-0.3-0.30.3-1.11.10.2-0.20.3-0.3-0.2-0.20.20.2-0.20.2-0.20.20.2-0.20.5-0.50.8-0.80.5
Bone: marrow area5.211.312.63.53.5-3.5-3.33.3-3.33.4-3.43.43.43.4-3.4-3.43.4-3.43.4-3.4-3.43.4-3.33.3-3.13.13.2
Bone: maximum diameter1.12.12.41.51.5-1.5-1.31.3-1.41.4-1.41.41.51.5-1.5-1.51.5-1.61.6-1.6-1.61.6-1.41.4-1.31.31.3
Bone: maximum force2.74.75.92.22.2-2.2-2.42.4-2.32.3-2.02.02.02.0-2.0-2.02.0-2.12.1-2.1-2.12.1-2.12.1-2.42.41.7
Bone: maximum moment2.03.45.01.91.8-1.8-2.22.2-2.01.9-1.71.71.71.7-1.7-1.71.7-1.81.8-1.8-1.81.8-1.81.8-2.12.11.4
Mean time between licks in bursts0.50.71.9-0.7-0.70.81.0-1.00.6-0.60.8-0.8-0.8-0.80.80.8-0.80.9-0.90.90.9-0.90.6-0.60.2-0.2-1.4
Mean num. licks in bursts0.20.30.80.50.5-0.5-0.20.2-0.60.6-0.40.40.40.4-0.4-0.40.4-0.50.5-0.5-0.50.5-0.60.6-0.90.9-0.1
Cd content in liver0.20.21.10.40.4-0.4-0.20.2-0.60.5-0.20.20.20.2-0.2-0.20.2-0.30.3-0.3-0.30.3-0.50.5-1.11.1-0.4
Co content in liver0.80.91.7-1.0-1.01.01.1-1.10.9-0.91.0-1.0-1.0-1.01.01.0-1.01.0-1.01.01.0-1.00.9-0.90.5-0.5-1.3
Cu content in liver0.10.10.30.30.3-0.3-0.60.6-0.30.3-0.30.30.30.3-0.3-0.30.3-0.30.3-0.3-0.30.3-0.20.2-0.10.10.6
Fe content in liver1.82.24.01.51.5-1.5-2.02.0-1.61.5-1.41.41.41.4-1.4-1.41.4-1.41.4-1.4-1.41.4-1.41.4-1.31.31.7
K content in liver0.00.00.0-0.0-0.00.0-0.10.10.0-0.0-0.00.00.00.0-0.0-0.00.0-0.00.0-0.0-0.00.00.0-0.00.1-0.10.1
Mg content in liver0.20.20.50.40.4-0.4-0.70.7-0.50.5-0.40.40.40.4-0.4-0.40.4-0.40.4-0.4-0.40.4-0.40.4-0.30.30.6
Mn content in liver2.02.22.6-1.6-1.61.61.4-1.41.5-1.61.5-1.5-1.5-1.51.51.5-1.51.4-1.41.41.4-1.41.5-1.51.4-1.4-1.3
Na content in liver1.11.12.11.11.1-1.1-1.21.2-1.01.0-1.11.11.11.1-1.1-1.11.1-1.01.0-1.0-1.01.0-1.01.0-0.50.51.4
Rb content in liver1.21.52.91.21.2-1.2-1.21.2-1.11.1-1.31.31.31.3-1.3-1.31.3-1.31.3-1.3-1.31.3-1.01.0-0.50.51.7
Se content in liver0.10.10.9-0.3-0.30.3-0.90.9-0.0-0.10.2-0.2-0.2-0.20.20.2-0.20.3-0.30.30.3-0.30.3-0.30.4-0.40.4
Sr content in liver0.40.41.2-0.5-0.60.60.0-0.00.1-0.20.7-0.7-0.7-0.70.70.7-0.70.7-0.70.70.7-0.70.3-0.3-0.60.6-1.1
Zn content in liver0.00.00.1-0.0-0.00.00.2-0.2-0.00.00.1-0.1-0.1-0.10.10.1-0.10.1-0.10.10.1-0.1-0.10.1-0.10.1-0.3
Bone: minimum diameter0.91.72.71.31.3-1.3-1.61.6-1.31.3-1.21.21.21.2-1.2-1.21.2-1.31.3-1.3-1.31.3-1.11.1-1.21.21.3
Time in familiar zone, hab. session 10.10.10.50.00.0-0.00.7-0.70.0-0.00.1-0.1-0.1-0.10.10.0-0.00.0-0.00.00.0-0.0-0.20.2-0.50.5-0.7
Time in novel zone, hab. session 10.10.10.4-0.1-0.00.0-0.50.50.0-0.0-0.10.10.00.0-0.0-0.00.00.0-0.00.00.0-0.00.2-0.20.5-0.50.6
Total zone transitions, hab. session 10.10.10.30.20.2-0.20.5-0.50.1-0.1-0.30.30.30.3-0.3-0.30.3-0.30.3-0.3-0.30.3-0.10.10.3-0.30.2
Total locomotion distance, hab. session 10.30.41.30.50.6-0.6-0.80.8-0.40.4-0.60.60.60.6-0.6-0.60.6-0.80.8-0.8-0.80.8-0.30.30.0-0.01.1
Locomotion velocity, hab. session 10.50.71.20.70.7-0.7-1.11.1-0.70.7-0.80.80.80.8-0.8-0.80.8-1.01.0-1.0-1.01.0-0.60.6-0.50.51.0
Time in familiar zone, hab. session 21.41.41.8-1.2-1.21.21.1-1.11.3-1.21.1-1.1-1.1-1.11.11.1-1.11.2-1.21.21.2-1.21.2-1.21.3-1.3-0.9
Time in novel zone, hab. session 20.60.61.10.70.7-0.7-1.01.0-0.80.8-0.60.60.70.7-0.7-0.70.7-0.70.7-0.7-0.70.7-0.60.6-0.90.90.6
Total zone transitions, hab. session 20.10.20.70.40.3-0.30.3-0.3-0.30.3-0.20.20.20.2-0.2-0.30.3-0.40.4-0.4-0.40.4-0.30.3-0.80.8-0.4
Total locomotion distance, hab. session 20.40.51.40.70.7-0.7-0.60.6-0.80.7-0.60.60.60.6-0.6-0.60.6-0.80.8-0.8-0.80.8-0.70.7-1.21.20.1
Locomotion velocity, hab. session 20.60.82.20.90.9-0.8-0.60.6-0.90.9-0.80.80.80.8-0.8-0.80.8-1.01.0-1.0-1.01.0-0.90.9-1.51.50.1
Novel to familiar place preference ratio1.92.05.11.31.3-1.3-2.32.3-1.51.5-1.31.31.31.3-1.3-1.31.3-1.21.2-1.2-1.21.2-1.21.1-1.11.11.7
Novelty place preference2.02.04.91.41.4-1.4-2.22.2-1.51.5-1.31.31.31.3-1.3-1.31.3-1.31.3-1.3-1.31.3-1.21.2-1.21.21.6
Time in novel zone, NPP test1.61.64.41.21.2-1.2-2.12.1-1.31.3-1.21.21.21.2-1.2-1.21.2-1.11.1-1.1-1.11.1-1.01.0-0.90.91.5
Total zone transitions, NPP test0.10.20.2-0.4-0.40.40.4-0.40.4-0.40.4-0.4-0.4-0.40.40.4-0.40.3-0.30.30.3-0.30.4-0.40.2-0.2-0.4
Total locomotion distance, NPP test0.20.20.5-0.6-0.60.6-0.20.20.5-0.50.5-0.5-0.5-0.50.50.6-0.60.3-0.30.30.3-0.30.7-0.70.5-0.50.0
Locomotion velocity, NPP test0.20.20.5-0.6-0.60.6-0.10.10.5-0.50.6-0.6-0.6-0.60.60.6-0.60.4-0.40.40.4-0.40.7-0.70.4-0.4-0.1
Intraocular pressure3.65.05.7-2.4-2.42.42.1-2.12.4-2.32.3-2.3-2.2-2.22.22.3-2.32.2-2.22.22.2-2.22.3-2.32.0-2.0-2.1
Delta distance traveled before/after self-admin2.52.63.3-1.8-1.81.80.9-0.91.5-1.61.8-1.8-1.8-1.81.81.7-1.71.7-1.71.71.7-1.71.8-1.81.4-1.4-1.4
Delta ambulatory time before/after self-admin1.92.12.7-1.6-1.61.60.2-0.21.3-1.31.7-1.7-1.6-1.61.61.6-1.61.5-1.51.51.5-1.51.7-1.71.2-1.2-1.2
Parametrial fat weight0.00.00.00.0-0.00.0-0.10.1-0.00.00.1-0.1-0.1-0.10.10.0-0.00.0-0.00.00.0-0.00.1-0.10.0-0.0-0.1
Pavlov. Cond. lever latency0.50.62.3-0.7-0.70.71.4-1.40.6-0.60.7-0.7-0.7-0.70.70.8-0.80.6-0.60.60.6-0.60.4-0.4-0.20.2-1.5
Pavlov. Cond. magazine entry latency0.30.42.00.50.5-0.5-1.21.2-0.40.4-0.60.60.60.6-0.6-0.60.6-0.50.5-0.5-0.50.5-0.30.30.4-0.41.4
Pavlov. Cond. change in total contacts0.20.21.90.10.1-0.1-0.80.8-0.0-0.0-0.30.30.30.3-0.3-0.30.3-0.20.2-0.2-0.20.20.2-0.10.9-0.91.4
Pavlov. Cond. index score0.40.52.10.50.5-0.5-1.51.5-0.50.5-0.60.60.60.6-0.6-0.60.6-0.50.5-0.5-0.50.5-0.30.30.3-0.31.4
Pavlov. Cond. latency score0.70.93.00.80.8-0.8-1.71.7-0.80.8-0.90.90.90.9-0.9-0.90.9-0.80.8-0.8-0.80.8-0.50.50.1-0.11.7
Pavlov. Cond. lever contacts0.40.42.10.50.5-0.5-1.41.4-0.50.5-0.60.60.60.6-0.6-0.60.6-0.40.4-0.4-0.40.4-0.20.30.3-0.31.4
Pavlov. Cond. magazine entry number0.50.61.9-0.7-0.70.71.1-1.10.6-0.60.8-0.8-0.8-0.80.80.8-0.80.7-0.70.70.7-0.70.5-0.5-0.10.1-1.4
Pavlov. Cond. intertrial magazine entries0.81.01.41.01.0-1.0-1.21.2-1.21.1-0.90.90.90.9-0.9-0.90.9-0.90.9-0.9-0.90.9-1.01.0-1.11.10.8
Pavlov. Cond. lever-magazine prob. diff.0.20.31.60.30.3-0.3-1.21.2-0.30.3-0.40.40.40.4-0.4-0.40.4-0.30.3-0.3-0.30.3-0.10.10.5-0.51.3
Pavlov. Cond. response bias0.30.31.30.40.4-0.4-1.11.1-0.40.4-0.50.50.50.5-0.5-0.50.5-0.40.4-0.4-0.40.4-0.30.30.2-0.21.1
Pavlov. Cond. lever latency0.20.21.10.40.4-0.4-0.60.6-0.70.7-0.20.20.20.2-0.2-0.20.2-0.20.2-0.2-0.20.2-0.50.5-1.01.0-0.3
Pavlov. Cond. magazine entry latency0.10.11.1-0.1-0.10.11.0-1.00.4-0.30.1-0.1-0.1-0.10.10.1-0.10.1-0.10.10.1-0.10.0-0.00.2-0.2-0.5
Pavlov. Cond. change in total contacts0.10.10.9-0.00.0-0.00.1-0.10.3-0.3-0.20.20.20.2-0.2-0.20.2-0.20.2-0.2-0.20.20.2-0.10.9-0.90.9
Pavlov. Cond. index score0.10.10.6-0.2-0.20.20.5-0.50.5-0.40.0-0.0-0.0-0.00.00.1-0.10.0-0.00.00.0-0.00.3-0.30.8-0.80.4
Pavlov. Cond. latency score0.10.10.4-0.2-0.10.10.4-0.40.4-0.40.0-0.0-0.0-0.00.00.0-0.00.0-0.00.00.0-0.00.2-0.20.6-0.60.3
Pavlov. Cond. lever contacts0.10.10.9-0.1-0.10.10.1-0.10.4-0.4-0.10.10.10.1-0.1-0.10.1-0.10.1-0.1-0.10.10.3-0.30.9-0.90.9
Pavlov. Cond. magazine entry number0.20.20.3-0.5-0.50.50.2-0.20.3-0.40.6-0.6-0.6-0.60.60.5-0.50.6-0.60.60.6-0.60.5-0.50.3-0.3-0.5
Pavlov. Cond. intertrial magazine entries0.10.20.3-0.4-0.40.4-0.50.50.2-0.20.4-0.4-0.4-0.40.40.4-0.40.4-0.40.40.4-0.40.5-0.50.5-0.50.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.6-0.2-0.20.20.5-0.50.5-0.50.1-0.1-0.1-0.10.10.1-0.10.1-0.10.10.1-0.10.3-0.30.8-0.80.4
Pavlov. Cond. response bias0.20.31.00.50.5-0.5-0.00.0-0.10.2-0.60.60.60.6-0.6-0.60.6-0.60.6-0.6-0.60.6-0.40.40.3-0.31.0
Time in closed arm before self-admin6.16.97.42.72.7-2.7-2.72.7-2.72.7-2.72.72.72.7-2.7-2.62.6-2.72.7-2.7-2.72.7-2.62.6-2.22.22.5
Time in closed arm after self-admin1.31.31.81.21.2-1.2-0.90.9-1.01.0-1.31.31.31.3-1.3-1.21.2-1.21.2-1.2-1.21.2-1.11.1-0.60.61.4
Time in open arm before self-admin8.39.010.5-3.2-3.23.22.4-2.42.8-2.83.2-3.2-3.2-3.23.23.2-3.23.2-3.23.23.2-3.22.9-2.92.2-2.2-3.1
Time in open arm after self-admin0.40.40.60.70.7-0.7-0.80.8-0.70.7-0.70.70.70.7-0.7-0.60.6-0.60.6-0.6-0.60.6-0.60.6-0.50.50.7
Bone: periosteal estimation3.47.17.72.82.7-2.7-2.72.7-2.72.7-2.62.62.62.6-2.6-2.72.7-2.72.7-2.7-2.72.7-2.62.6-2.52.52.5
Bone: periosteal perimeter2.54.14.62.12.1-2.1-2.12.1-2.02.0-2.02.02.02.0-2.0-2.02.0-2.12.1-2.1-2.12.1-1.91.9-1.91.91.9
Bone: post-yield work1.01.42.11.21.2-1.2-1.51.5-1.31.3-1.11.11.11.1-1.1-1.11.1-1.11.1-1.1-1.11.1-1.21.2-1.51.50.7
Progressive ratio test 1 active lever presses0.10.10.2-0.0-0.10.1-0.20.2-0.10.10.2-0.2-0.1-0.20.20.2-0.20.3-0.30.30.3-0.3-0.10.1-0.40.4-0.4
Progressive ratio test 1 breakpoint0.00.00.20.10.0-0.0-0.30.3-0.20.20.1-0.1-0.0-0.00.00.0-0.00.1-0.10.10.1-0.1-0.10.1-0.50.5-0.3
Progressive ratio test 1 inactive lever presses3.33.66.8-1.9-2.02.01.3-1.31.4-1.42.1-2.1-2.2-2.12.12.2-2.22.2-2.22.22.2-2.21.5-1.50.2-0.2-2.6
Progressive ratio test 2 active lever presses0.10.10.90.30.3-0.3-0.20.2-0.50.5-0.10.10.20.2-0.2-0.20.2-0.10.1-0.1-0.10.1-0.40.4-0.90.9-0.5
Progressive ratio test 2 breakpoint0.10.10.5-0.2-0.20.2-0.00.00.0-0.00.4-0.4-0.3-0.30.30.3-0.30.4-0.40.40.4-0.40.2-0.2-0.30.3-0.7
Progressive ratio test 2 inactive lever presses0.40.50.9-0.7-0.70.70.2-0.20.4-0.40.7-0.7-0.8-0.80.80.8-0.80.9-0.90.90.9-0.90.5-0.50.1-0.1-1.0
Incentive Sensitization - Responses0.50.51.30.80.8-0.8-0.50.5-0.90.9-0.60.60.70.7-0.7-0.70.7-0.70.7-0.7-0.70.7-0.80.8-1.11.1-0.0
Incentive Sensitization - Breakpoint0.40.41.10.70.7-0.6-0.40.4-0.80.8-0.50.50.60.6-0.6-0.60.6-0.60.6-0.6-0.60.6-0.70.7-1.01.0-0.1
Sum of active levers in priming session hrs 5-61.21.21.71.11.1-1.1-1.31.3-1.21.1-1.11.11.11.1-1.1-1.11.1-1.11.1-1.1-1.11.1-1.01.0-0.80.81.2
Progressive ratio0.81.02.1-0.9-0.80.81.5-1.51.0-0.90.9-0.9-0.9-0.90.90.9-0.91.1-1.11.11.1-1.10.7-0.70.9-0.9-1.3
Food seeking constrained by brief footshock0.00.00.30.20.1-0.10.2-0.2-0.10.1-0.10.10.10.1-0.1-0.10.1-0.20.2-0.2-0.20.2-0.20.2-0.50.5-0.2
Seeking ratio, punishment vs. effort1.21.52.31.21.1-1.1-1.31.3-1.31.2-1.11.11.11.1-1.1-1.11.1-1.31.3-1.3-1.31.3-1.01.0-1.51.51.1
Retroperitoneal fat weight0.00.21.0-0.3-0.30.3-1.01.0-0.10.00.3-0.3-0.3-0.40.40.3-0.30.4-0.40.40.4-0.40.3-0.3-0.10.1-0.1
Reaction time number correct0.40.60.9-0.8-0.80.80.5-0.50.8-0.80.7-0.7-0.8-0.80.80.7-0.70.7-0.70.70.7-0.70.9-0.90.9-0.9-0.4
Reaction time mean minus median0.40.51.60.50.5-0.5-1.31.3-1.00.9-0.40.40.50.4-0.4-0.40.4-0.40.4-0.4-0.40.4-0.60.6-1.21.20.3
Reaction time mean minus median AUC0.20.30.80.40.4-0.4-0.90.9-0.80.7-0.40.40.40.4-0.4-0.30.3-0.30.3-0.3-0.30.3-0.40.4-0.80.80.3
Reaction time num false alarms3.85.25.9-2.4-2.42.42.3-2.32.3-2.32.4-2.4-2.4-2.32.32.3-2.32.2-2.22.22.2-2.22.2-2.21.8-1.8-2.4
Reaction time num false alarms AUC4.36.06.9-2.5-2.52.52.6-2.62.5-2.52.6-2.6-2.5-2.52.52.5-2.52.4-2.42.42.4-2.42.4-2.41.9-1.9-2.6
Reaction time trials correct on left0.40.60.9-0.8-0.80.80.5-0.50.8-0.80.7-0.7-0.8-0.80.80.7-0.70.7-0.70.70.7-0.70.9-0.90.9-0.9-0.4
Reaction time trials on left0.30.50.7-0.8-0.70.70.4-0.40.8-0.80.7-0.7-0.7-0.70.70.7-0.70.6-0.60.60.6-0.60.8-0.80.9-0.9-0.4
Reaction time mean1.52.13.61.51.4-1.4-1.61.6-1.81.7-1.31.31.41.3-1.3-1.31.3-1.31.3-1.3-1.31.3-1.51.5-1.91.90.9
Reaction time mean AUC1.01.32.81.11.1-1.1-1.51.5-1.51.4-0.90.91.00.9-0.9-1.01.0-0.90.9-0.9-0.90.9-1.21.2-1.71.70.5
Median of all reaction times1.52.03.21.51.5-1.5-1.41.4-1.71.6-1.31.31.41.3-1.3-1.31.3-1.31.3-1.3-1.31.3-1.51.5-1.81.80.9
Reaction time omissions0.30.41.50.50.5-0.5-1.21.2-0.70.7-0.50.50.40.5-0.5-0.50.5-0.40.4-0.4-0.40.4-0.60.6-0.90.90.3
Reaction time false alarm rate2.02.83.7-1.7-1.71.71.9-1.91.7-1.71.8-1.8-1.7-1.71.71.7-1.71.7-1.71.71.7-1.71.5-1.51.1-1.1-1.9
Reaction time premature initiation rate1.52.06.3-1.5-1.51.50.6-0.61.6-1.61.2-1.2-1.2-1.21.21.3-1.31.3-1.31.31.3-1.31.7-1.72.5-2.50.3
Reaction time premature initiations2.23.18.1-1.9-1.81.80.8-0.81.9-2.01.6-1.6-1.6-1.61.61.6-1.61.6-1.61.61.6-1.62.1-2.12.8-2.8-0.1
Std. dev. reaction times1.31.93.21.31.3-1.3-1.81.8-1.61.6-1.21.21.31.3-1.3-1.21.2-1.21.2-1.2-1.21.2-1.41.4-1.71.71.0
Reaction time trials completed0.30.50.7-0.8-0.70.70.4-0.40.8-0.80.7-0.7-0.7-0.70.70.7-0.70.6-0.60.60.6-0.60.8-0.80.9-0.9-0.4
Reaction time trials AUC0.40.60.8-0.8-0.80.80.5-0.50.8-0.80.8-0.8-0.8-0.80.80.7-0.70.7-0.70.70.7-0.70.9-0.90.9-0.9-0.5
Run reversals in cocaine runway, females0.10.10.80.10.1-0.10.9-0.90.1-0.00.1-0.10.20.2-0.2-0.00.0-0.00.0-0.0-0.00.0-0.10.1-0.40.4-0.9
Run reversals in cocaine runway, males0.10.10.7-0.3-0.30.3-0.20.20.4-0.40.2-0.2-0.2-0.20.20.2-0.20.2-0.20.20.2-0.20.5-0.50.9-0.90.4
Latency to leave start box in cocaine runway6.97.58.1-2.8-2.82.82.7-2.72.8-2.82.8-2.8-2.7-2.82.82.7-2.72.8-2.82.82.8-2.82.7-2.72.4-2.4-2.5
Latency to leave start box in cocaine runway, F5.86.47.4-2.6-2.62.62.7-2.72.5-2.52.6-2.6-2.5-2.62.62.5-2.52.5-2.52.52.5-2.52.4-2.42.1-2.1-2.6
Latency to leave start box in cocaine runway, M1.00.91.4-1.1-1.00.91.0-1.01.2-1.10.9-0.9-0.9-0.90.90.9-0.91.0-1.01.01.0-1.01.0-1.01.1-1.1-0.7
Std. dev. time between licks in bursts4.14.95.9-2.4-2.42.41.4-1.42.2-2.22.3-2.3-2.3-2.32.32.3-2.32.3-2.32.32.3-2.32.3-2.32.0-2.0-2.0
Total sessions with >9 infusions1.21.31.9-1.2-1.21.20.9-0.90.9-1.01.4-1.4-1.3-1.31.31.3-1.31.2-1.21.21.2-1.21.1-1.10.5-0.5-1.4
Short access day 1 total inactive lever presses0.40.41.0-0.7-0.60.6-0.90.90.4-0.50.3-0.3-0.6-0.50.50.6-0.60.7-0.70.70.7-0.70.6-0.61.0-1.00.4
Short access day 10 total inactive lever presses0.20.20.3-0.6-0.50.50.2-0.20.3-0.40.3-0.3-0.5-0.50.50.6-0.60.6-0.60.60.6-0.60.3-0.30.3-0.3-0.2
Short access day 1 total infusions0.30.30.5-0.6-0.60.6-0.30.30.4-0.40.7-0.7-0.7-0.70.70.7-0.70.4-0.40.40.4-0.40.6-0.60.0-0.0-0.6
Short access day 10 total infusions0.30.32.40.40.4-0.4-1.61.6-0.60.6-0.30.30.30.3-0.3-0.40.4-0.30.3-0.3-0.30.3-0.20.2-0.30.30.7
Short access total infusions0.30.30.4-0.6-0.60.6-0.40.40.3-0.40.7-0.7-0.6-0.60.60.6-0.60.5-0.50.50.5-0.50.6-0.60.2-0.2-0.5
Short access day 1 locomotion0.30.31.0-0.5-0.50.50.4-0.40.4-0.40.7-0.7-0.6-0.60.60.6-0.60.7-0.70.70.7-0.70.4-0.40.1-0.1-1.0
Short access day 10 total locomotion0.10.10.5-0.3-0.20.2-0.60.60.1-0.20.1-0.1-0.2-0.20.20.2-0.20.2-0.20.20.2-0.20.4-0.40.7-0.70.4
Short access total locomotion0.10.10.30.20.2-0.2-0.40.4-0.30.3-0.10.10.10.1-0.1-0.10.1-0.10.1-0.1-0.10.1-0.20.2-0.50.5-0.2
One hour access (0.3 mA shock)0.10.21.80.20.1-0.1-1.31.3-0.30.3-0.00.00.20.1-0.1-0.20.2-0.00.0-0.0-0.00.00.0-0.0-0.00.00.4
Compulsive drug intake0.10.10.2-0.2-0.20.20.5-0.50.4-0.40.2-0.2-0.2-0.20.20.2-0.20.3-0.30.30.3-0.30.2-0.20.3-0.3-0.4
One hour access (shock baseline)0.50.63.50.60.6-0.6-1.91.9-0.90.9-0.40.40.60.6-0.6-0.60.6-0.50.5-0.5-0.50.5-0.40.4-0.50.50.9
Social response proportion4.44.87.42.22.2-2.2-2.72.7-2.32.3-2.12.12.12.1-2.1-2.22.2-2.12.1-2.1-2.12.1-2.02.0-2.02.02.2
Social responses0.91.24.41.00.9-0.9-2.12.1-1.31.2-0.80.80.70.7-0.7-0.80.8-0.90.9-0.9-0.90.9-0.80.8-1.41.40.9
Social time0.20.21.30.30.3-0.3-1.11.1-0.70.6-0.30.30.30.3-0.3-0.20.2-0.20.2-0.2-0.20.2-0.30.3-0.80.80.1
Soleus weight0.10.40.80.50.5-0.5-0.90.9-0.60.6-0.60.60.60.6-0.6-0.60.6-0.60.6-0.6-0.60.6-0.50.5-0.30.30.9
Bone: stiffness3.14.97.72.32.3-2.3-2.22.2-2.42.4-2.12.12.12.1-2.1-2.12.1-2.12.1-2.1-2.12.1-2.32.3-2.82.81.3
Tibialis anterior weight0.62.03.0-1.4-1.41.41.7-1.71.4-1.41.5-1.5-1.4-1.41.41.4-1.41.4-1.41.41.4-1.41.3-1.31.0-1.0-1.6
Time to tail flick, vehicle, before self-admin0.20.21.5-0.2-0.20.21.2-1.20.2-0.20.2-0.2-0.2-0.20.20.2-0.20.2-0.20.20.2-0.20.0-0.0-0.10.1-0.8
Time to tail flick, vehicle, after self-admin0.30.30.40.60.6-0.60.4-0.4-0.50.5-0.50.50.60.6-0.6-0.50.5-0.60.6-0.6-0.60.6-0.60.6-0.60.60.2
Time to tail flick, test, before self-admin0.60.61.1-0.9-0.90.80.7-0.70.8-0.80.7-0.7-0.7-0.70.70.8-0.80.7-0.70.70.7-0.70.8-0.81.0-1.0-0.5
Time to tail flick, test, after self-admin1.11.21.7-1.2-1.21.21.0-1.01.0-1.01.1-1.1-1.2-1.21.21.2-1.21.2-1.21.21.2-1.20.9-0.90.4-0.4-1.3
Delta time to tail flick, vehicle, before/after SA0.00.00.10.00.0-0.0-0.40.4-0.10.10.0-0.00.00.0-0.0-0.00.00.1-0.10.10.1-0.1-0.00.00.0-0.00.2
Delta time to tail flick, test, before/after SA0.40.30.5-0.5-0.60.60.5-0.50.5-0.50.6-0.6-0.6-0.60.60.6-0.60.7-0.70.70.7-0.70.4-0.50.1-0.1-0.7
Tibia length6.016.820.84.44.4-4.4-3.23.2-4.34.3-4.14.14.14.1-4.1-4.14.1-4.04.0-4.0-4.04.0-4.44.4-4.64.62.8
Ambulatory time before self-admin1.01.11.51.01.0-1.0-1.21.2-1.11.1-1.21.21.11.1-1.1-1.01.0-0.90.9-0.9-0.90.9-1.11.1-0.70.71.2
Ambulatory time after self-admin1.92.13.0-1.7-1.61.60.1-0.11.3-1.41.4-1.4-1.5-1.51.51.6-1.61.5-1.51.51.5-1.51.6-1.61.7-1.7-0.7
Bone: tissue strength0.50.51.90.70.6-0.6-0.40.4-0.80.8-0.50.50.50.5-0.5-0.50.5-0.50.5-0.5-0.50.5-0.80.8-1.41.4-0.4
Total heroin consumption0.00.00.10.10.1-0.1-0.20.2-0.30.2-0.20.20.10.1-0.1-0.10.1-0.20.2-0.2-0.20.2-0.20.2-0.20.20.1
Bone: trabecular number5.07.98.83.03.0-3.0-2.22.2-2.72.8-2.92.92.92.9-2.9-2.82.8-2.92.9-2.9-2.92.9-2.92.9-2.72.72.3
Bone: trabecular spacing0.50.61.2-0.8-0.80.81.1-1.10.9-0.90.6-0.6-0.7-0.70.70.8-0.80.8-0.80.80.8-0.80.7-0.70.9-0.9-0.7
Bone: trabecular thickness2.42.93.31.81.8-1.8-1.61.6-1.61.6-1.71.71.81.8-1.8-1.81.8-1.71.7-1.7-1.71.7-1.61.6-1.31.31.8
Bone: trabecular tissue density0.30.51.1-0.7-0.70.70.5-0.50.5-0.50.7-0.7-0.7-0.70.70.7-0.70.8-0.80.80.8-0.80.5-0.60.2-0.2-1.0
Water consumed over 24 hours0.60.81.1-0.9-0.90.90.7-0.71.0-1.00.8-0.8-0.8-0.80.80.8-0.80.8-0.80.80.8-0.80.9-0.91.0-1.0-0.7
Number of responses in last shaping day1.31.33.5-1.1-1.11.11.5-1.50.9-0.91.2-1.2-1.2-1.21.21.2-1.21.2-1.21.21.2-1.20.8-0.80.1-0.1-1.9