Hub : Genes

Sf3a2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Sf3a2 0.13 0.09 3.3e-07 0.08 0.1 0.1 0.1 3.8e-05 5.2e-06 4.4e-06 3.6e-06
2 NAcc mRNA stability Sf3a2 0.06 0.05 1.3e-07 0.06 0.06 0.05 0.06 1.2e-07 5.4e-08 1.1e-06 1.1e-07
3 Adipose gene expression Sf3a2 0.05 0.03 2.3e-06 0.05 0.04 0.04 0.05 3.8e-06 1.0e-05 1.2e-05 5.0e-06
4 Brain alternative TSS XM_006240886.3 0.03 0.03 3.1e-03 0.03 0.02 0.02 0.02 1.8e-03 3.5e-03 5.2e-03 2.9e-03
5 Brain gene expression Sf3a2 0.1 0.06 3.8e-11 0.11 0.1 0.09 0.1 2.4e-10 2.5e-09 4.3e-09 1.1e-09
6 Brain isoform ratio XM_006240886.3 0.04 0.03 1.0e-03 0.03 0.03 0.03 0.03 4.4e-04 1.2e-03 2.0e-03 7.5e-04
7 Brain alternative TSS NM_001011986.1 0.06 0.05 2.1e-05 0.05 0.05 0.05 0.05 2.1e-05 4.2e-05 4.2e-05 3.8e-05
8 Liver mRNA stability Sf3a2 0.02 0.02 3.2e-03 0.02 0.02 0.01 0.01 3.1e-03 4.8e-03 9.4e-03 1.3e-02
9 Brain mRNA stability Sf3a2 0.12 0.07 1.9e-11 0.11 0.11 0.1 0.11 5.0e-10 1.0e-10 2.5e-09 3.8e-10
10 PL mRNA stability Sf3a2 0.12 0.08 2.6e-15 0.14 0.15 0.14 0.14 1.1e-15 7.1e-16 1.1e-15 1.4e-15
11 PL gene expression Sf3a2 0.05 0.03 9.6e-07 0.06 0.06 0.06 0.06 2.3e-07 1.6e-07 2.1e-07 4.0e-07
12 NAcc gene expression Sf3a2 0.02 0.02 9.4e-03 0.01 0.01 0.01 0.01 3.3e-02 1.1e-02 9.5e-03 2.0e-02
13 Brain isoform ratio NM_001011986.1 0.07 0.06 4.5e-06 0.06 0.06 0.06 0.06 3.5e-06 6.5e-06 2.6e-06 4.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.60.94.0-0.20.40.7-0.70.7-0.70.7-0.70.91.1-1.22.01.2
Area under the delay curve2.42.53.01.51.71.6-1.71.7-1.71.7-1.71.71.6-1.61.21.2
BMI with tail5.618.223.74.94.74.5-4.54.5-4.44.4-4.54.34.1-4.02.53.6
BMI without tail1.53.15.92.42.11.8-1.91.9-1.91.9-1.91.71.4-1.40.11.0
Body weight1.04.05.42.32.22.1-2.12.1-2.12.1-2.12.11.9-1.91.11.6
Weight adjusted by age0.10.20.60.70.50.3-0.30.3-0.30.3-0.30.2-0.00.1-0.8-0.2
Bone surface0.50.96.0-1.00.00.4-0.40.4-0.40.4-0.40.71.1-1.22.41.0
Bone volume0.50.95.6-1.00.00.4-0.40.4-0.30.3-0.40.71.0-1.22.40.8
Breakpoint value in progressive ratio session5.96.57.2-2.6-2.6-2.62.6-2.62.6-2.62.6-2.7-2.72.7-2.3-2.0
Number of licking bursts0.10.10.90.3-0.0-0.10.1-0.10.1-0.10.1-0.3-0.40.5-1.0-0.3
Context. condit. distance diff. score0.20.30.40.60.60.5-0.60.6-0.60.6-0.60.50.4-0.40.10.4
Locomotion velocity, session 10.20.20.8-0.9-0.6-0.60.5-0.50.5-0.50.4-0.3-0.10.10.60.3
Locomotion distance, session 10.40.53.5-0.5-0.10.2-0.20.2-0.20.2-0.20.30.7-0.71.91.3
Locomotion velocity, session 21.82.14.6-2.2-1.8-1.81.6-1.61.6-1.61.5-1.3-0.90.80.6-0.3
Locomotion distance, session 20.70.92.6-1.6-1.3-1.01.0-1.01.0-1.00.9-0.7-0.20.21.30.4
Locomotion velocity, session 36.17.17.7-2.7-2.7-2.82.8-2.82.8-2.82.7-2.7-2.62.6-2.0-2.6
Locomotion distance, session 30.00.00.10.00.00.0-0.00.0-0.00.00.0-0.0-0.20.1-0.40.1
Stereotopy head waving bouts, day 33.84.46.2-2.5-2.4-2.32.3-2.32.3-2.32.2-2.1-1.91.8-0.8-1.8
Stereotopy head waving duration, day 34.95.97.1-2.7-2.6-2.62.6-2.62.6-2.62.5-2.4-2.22.2-1.3-2.3
Locomotion velocity, session 70.70.81.2-1.0-0.7-0.90.9-0.90.8-0.80.8-0.7-0.90.8-0.9-1.1
Locomotion distance, session 70.10.10.80.40.20.0-0.10.1-0.10.1-0.10.0-0.30.2-0.9-0.2
Stereotopy head waving bouts, day 70.20.21.1-0.20.20.3-0.20.2-0.20.2-0.30.40.6-0.61.10.4
Stereotopy head waving duration, day 70.10.10.9-0.7-0.3-0.10.1-0.10.1-0.10.10.10.2-0.30.90.1
Locomotion velocity, session 80.20.31.5-0.9-0.5-0.40.4-0.40.4-0.40.3-0.10.2-0.31.20.1
Locomotion distance, session 80.10.10.4-0.4-0.3-0.30.2-0.20.2-0.20.2-0.10.1-0.10.60.5
Degree of sensitization distance0.30.30.40.60.60.6-0.60.6-0.60.6-0.60.60.6-0.60.40.4
Degree of sensitization stereotypy2.52.73.11.21.61.7-1.71.7-1.71.7-1.61.71.7-1.81.71.6
Conditioned locomotion0.70.82.61.61.20.9-0.90.9-0.90.9-0.90.80.7-0.5-0.30.2
Cocaine response after cond. corrected3.13.56.92.62.31.9-2.02.0-2.02.0-2.11.81.4-1.4-0.01.2
Cocaine response after cond. not corrected3.33.67.62.82.42.0-2.12.1-2.12.1-2.11.81.5-1.4-0.11.1
Cocaine response before conditioning0.40.50.9-0.8-0.7-0.70.7-0.70.7-0.70.7-0.6-0.60.5-0.3-1.0
Saline control response0.00.00.20.30.20.1-0.20.2-0.10.1-0.10.10.1-0.1-0.00.4
Bone: connectivity density0.91.33.30.30.81.0-1.11.1-1.01.0-1.01.21.3-1.41.81.5
Bone: cortical apparent density0.70.91.11.11.01.0-1.01.0-1.01.0-1.00.90.9-0.90.60.9
Bone: cortical area0.81.21.80.61.11.1-1.11.1-1.11.1-1.11.31.2-1.31.30.6
Bone: cortical porosity0.30.30.8-0.9-0.7-0.50.6-0.60.6-0.60.6-0.5-0.40.30.2-0.5
Bone: cortical porosity0.10.21.1-0.30.00.2-0.10.1-0.10.1-0.10.30.4-0.51.10.3
Bone: cortical thickness1.22.02.31.21.41.5-1.41.4-1.41.4-1.41.51.5-1.51.31.0
Bone: cortical thickness0.20.21.10.0-0.1-0.30.3-0.30.3-0.30.3-0.3-0.60.5-1.0-0.7
Bone: cortical tissue density0.50.60.80.90.80.8-0.80.8-0.80.8-0.80.80.8-0.70.50.7
Condit. Reinf. active minus inactive responses3.84.25.0-2.2-2.2-2.22.2-2.22.2-2.22.1-2.1-2.01.9-1.3-1.9
Condit. Reinf. active-inactive response ratio2.62.83.2-1.5-1.6-1.61.7-1.71.7-1.71.6-1.7-1.71.7-1.6-1.8
Condit. Reinf. active responses2.53.15.1-2.3-2.1-1.91.9-1.91.9-1.91.9-1.7-1.51.4-0.3-1.2
Condit. Reinf. inactive responses0.40.41.2-1.1-0.9-0.70.7-0.70.6-0.60.6-0.5-0.20.10.90.1
Incentive salience index mean1.41.73.1-1.8-1.6-1.41.4-1.41.4-1.41.4-1.3-1.11.0-0.2-1.0
Condit. Reinf. lever presses0.40.63.4-0.40.10.4-0.40.4-0.30.3-0.40.60.8-0.91.91.1
Condit. Reinf. active minus inactive responses2.93.64.3-1.7-1.8-1.81.9-1.91.9-1.91.9-2.0-2.12.1-2.0-1.8
Condit. Reinf. active-inactive response ratio0.50.51.6-0.2-0.5-0.60.6-0.60.6-0.60.6-0.8-0.91.0-1.3-0.4
Condit. Reinf. active responses2.43.33.7-1.9-1.8-1.81.8-1.81.8-1.81.8-1.8-1.91.8-1.7-1.9
Condit. Reinf. inactive responses1.11.32.7-1.3-1.1-1.11.1-1.11.2-1.21.1-1.0-1.11.0-0.9-1.6
Condit. Reinf. lever presses2.94.04.4-1.8-1.9-2.02.0-2.02.0-2.02.0-2.0-2.12.1-2.0-2.1
Condit. Reinf. lever reinforcers received2.12.93.6-1.6-1.6-1.61.6-1.61.7-1.71.7-1.7-1.81.8-1.8-1.9
Conditioned reinforcement - actives2.22.22.7-1.7-1.6-1.41.4-1.41.5-1.51.6-1.5-1.61.5-1.1-1.1
Conditioned reinforcement - inactives0.30.30.70.80.70.6-0.60.6-0.60.6-0.60.50.4-0.4-0.20.4
Conditioned locomotion6.88.210.8-3.3-3.2-2.92.9-2.92.9-2.92.9-3.0-3.02.9-2.1-2.1
Patch foraging indifference point 0 sec0.20.30.30.40.50.5-0.50.5-0.50.5-0.50.60.6-0.60.60.3
Patch foraging indifference point AUC0.91.11.3-1.0-1.1-1.01.0-1.01.0-1.01.1-1.1-1.11.1-0.9-0.6
Delay disc. indifference point, 0s delay9.210.112.12.63.03.2-3.13.1-3.13.1-3.13.33.5-3.53.53.3
Delay disc. indifference point, 16s delay0.20.20.20.40.40.4-0.50.5-0.50.5-0.50.40.4-0.40.30.2
Delay disc. indifference point, 2s delay6.37.07.82.52.72.8-2.72.7-2.72.7-2.72.82.8-2.82.32.3
Delay disc. indifference point, 24s delay0.50.50.80.90.80.7-0.80.8-0.80.8-0.80.80.5-0.60.30.5
Delay disc. indifference point, 4s delay1.51.61.91.01.31.2-1.31.3-1.31.3-1.31.41.3-1.41.20.9
Delay disc. indifference point, 8s delay0.80.81.31.11.11.0-1.01.0-1.01.0-1.01.00.8-0.80.20.5
Indifference point function ln k0.20.30.40.60.60.5-0.60.6-0.60.6-0.60.60.4-0.50.00.2
Indifference point function log k0.20.30.40.60.60.5-0.60.6-0.60.6-0.60.60.4-0.50.00.2
Patch foraging total patch changes 0 sec0.10.10.20.40.40.4-0.40.4-0.40.4-0.30.40.4-0.40.40.2
Patch foraging total patch changes 12 sec0.10.10.50.70.50.4-0.40.4-0.40.4-0.40.30.2-0.1-0.20.2
Patch foraging total patch changes 18 sec1.11.41.6-1.2-1.3-1.21.2-1.21.2-1.21.3-1.2-1.21.2-0.8-0.9
Patch foraging total patch changes 24 sec0.10.10.1-0.2-0.3-0.30.3-0.30.3-0.30.3-0.3-0.20.2-0.0-0.1
Patch foraging total patch changes 6 sec0.20.30.4-0.6-0.6-0.60.6-0.60.6-0.60.6-0.5-0.40.4-0.1-0.6
Patch foraging time to switch 0 sec2.13.26.71.31.61.6-1.51.5-1.61.6-1.71.82.2-2.12.61.6
Patch foraging water rate 0 sec0.40.63.60.0-0.3-0.30.3-0.30.3-0.30.4-0.6-1.01.0-1.9-0.7
Patch foraging water rate 12 sec0.40.62.01.41.00.7-0.80.8-0.80.8-0.80.60.2-0.2-0.90.2
Patch foraging water rate 18 sec1.21.67.90.0-0.6-0.90.8-0.80.8-0.80.8-1.2-1.61.7-2.8-1.3
Patch foraging water rate 24 sec0.40.54.50.90.20.0-0.10.1-0.10.10.0-0.4-0.80.9-2.1-0.5
Patch foraging water rate 6 sec1.01.54.8-0.5-0.8-1.11.0-1.01.0-1.01.0-1.2-1.51.5-2.2-1.3
Seeking ratio, delayed vs. immediate footshock3.64.16.4-2.5-2.3-2.12.1-2.12.1-2.12.2-2.0-2.01.9-1.1-1.5
Distance traveled before self-admin0.70.82.10.50.60.9-0.90.9-0.90.9-0.70.80.7-0.80.91.4
Distance traveled after self-admin0.50.61.3-1.2-0.9-0.80.7-0.70.7-0.70.8-0.7-0.80.7-0.3-0.3
Extensor digitorum longus weight3.714.519.84.54.24.2-4.14.1-4.14.1-4.13.83.4-3.31.63.4
Bone: elastic displacement0.20.20.4-0.6-0.5-0.50.5-0.50.5-0.50.5-0.5-0.40.4-0.2-0.1
Bone: elastic work0.30.40.50.30.60.5-0.60.6-0.60.6-0.60.70.6-0.70.50.6
Bone: endosteal estimation0.30.60.80.50.80.7-0.80.8-0.80.8-0.80.90.8-0.90.70.6
Bone: endosteal perimeter0.10.20.8-0.9-0.5-0.50.4-0.40.4-0.40.4-0.3-0.30.10.2-0.4
Epididymis fat weight0.30.60.8-0.5-0.8-0.80.8-0.80.8-0.80.8-0.9-0.70.9-0.8-0.7
Delta time in closed arm before/after self-admin0.40.31.81.20.50.4-0.40.4-0.40.4-0.30.0-0.30.3-1.30.0
Delta time in open arm before/after self-admin1.31.31.61.01.21.1-1.11.1-1.11.1-1.11.21.3-1.31.20.9
Diff in mean of infusions in LGA sessions1.61.82.2-1.4-1.5-1.51.4-1.41.4-1.41.4-1.4-1.31.3-0.9-0.9
Delay discount exponential model param2.12.22.6-1.4-1.6-1.51.6-1.61.6-1.61.6-1.6-1.51.5-1.0-1.0
Extinction: sum of active levers before priming1.71.72.6-1.1-1.3-1.21.2-1.21.2-1.21.3-1.5-1.51.6-1.6-1.0
Active lever presses in extinction session 62.52.44.3-2.1-1.8-1.61.6-1.61.6-1.61.6-1.6-1.61.5-1.0-0.8
Bone: final force1.52.43.01.21.61.6-1.51.5-1.61.6-1.61.71.6-1.71.50.9
Bone: final moment1.11.92.41.01.41.4-1.41.4-1.41.4-1.41.61.5-1.61.30.8
Food consumed during 24 hour testing period0.50.60.90.80.80.9-0.90.9-0.90.9-0.90.70.6-0.60.20.6
Glucose1.21.82.11.41.41.4-1.51.5-1.51.5-1.51.31.2-1.20.71.4
Heart weight0.60.81.3-0.5-0.8-0.90.9-0.90.9-0.90.8-0.9-1.01.0-1.1-1.0
Delay discount hyperbolic model param3.03.13.7-1.7-1.9-1.91.9-1.91.9-1.91.9-1.9-1.81.8-1.3-1.3
Intermittent access intake day 1-15 change7.06.97.6-2.7-2.8-2.72.7-2.72.7-2.72.6-2.7-2.82.7-2.2-2.3
Intermittent access intake escalation7.87.79.3-2.5-2.8-2.72.7-2.72.8-2.82.6-2.9-3.13.0-2.8-2.5
Intermittent access intake escalation 29.99.711.0-2.8-3.1-3.13.1-3.13.2-3.23.1-3.2-3.33.3-3.0-3.1
Intermitt. access day 1 inactive lever presses0.40.51.5-0.6-0.6-0.50.5-0.50.5-0.50.5-0.8-1.00.9-1.2-0.2
Intermitt. access day 15 inactive lever presses0.60.70.8-0.8-0.8-0.90.9-0.90.8-0.80.8-0.8-0.90.9-0.8-0.9
Intermitt. access escalation Index0.80.71.50.30.60.8-0.80.8-0.80.8-0.70.80.9-0.91.21.1
Intermittent access day 1 total infusions0.00.10.10.10.30.2-0.20.2-0.20.2-0.30.30.3-0.30.2-0.0
Intermittent access day 15 total infusions2.42.73.1-1.5-1.6-1.71.7-1.71.6-1.61.6-1.7-1.71.7-1.7-1.7
Intermittent access terminal intake (last 3 days)1.31.41.6-1.2-1.2-1.21.2-1.21.2-1.21.1-1.2-1.31.2-1.1-1.3
Intermittent access total infusions0.30.30.5-0.5-0.5-0.50.5-0.50.5-0.50.5-0.6-0.60.6-0.7-0.6
Intermittent access day 1 locomotion0.40.40.5-0.6-0.6-0.70.7-0.70.7-0.70.6-0.7-0.60.7-0.6-0.7
Intermittent access day 15 total locomotion3.63.94.5-2.1-2.1-2.02.0-2.02.1-2.11.9-2.1-2.02.0-1.5-1.7
Intermittent access total locomotion0.81.01.5-1.2-1.1-1.01.0-1.01.0-1.00.9-1.1-1.11.0-0.7-0.6
Intermittent access standard deviation3.53.74.4-1.9-1.9-1.91.9-1.91.9-1.91.8-2.0-2.12.0-1.9-1.8
Left kidney weight0.00.00.3-0.3-0.1-0.10.1-0.10.1-0.10.10.10.1-0.20.60.2
Right kidney weight1.23.54.6-2.1-2.0-2.02.0-2.01.9-1.92.0-1.9-1.81.7-1.1-1.6
Cocaine induced anxiety0.30.40.9-1.0-0.8-0.70.7-0.70.7-0.70.7-0.5-0.30.20.6-0.3
Post-drug Anxiety0.30.40.7-0.7-0.5-0.70.7-0.70.7-0.70.6-0.20.0-0.10.7-0.8
Baseline Anxiety0.40.41.9-0.1-0.3-0.60.6-0.60.6-0.60.5-0.5-0.50.6-0.9-1.4
Tail length3.39.911.0-3.1-3.2-3.33.2-3.23.2-3.23.2-3.2-3.33.2-2.7-2.8
Length with tail1.65.87.9-2.8-2.6-2.62.6-2.62.5-2.52.6-2.4-2.32.2-1.4-2.0
Length without tail0.10.10.9-0.5-0.20.00.0-0.00.0-0.00.00.20.3-0.41.00.4
Times rat made contact with spout0.10.10.30.50.40.3-0.30.3-0.30.3-0.30.20.0-0.0-0.50.0
Lifetime Intake0.10.10.2-0.3-0.3-0.30.3-0.30.3-0.30.3-0.3-0.30.4-0.4-0.3
Liver weight, left2.03.25.12.32.01.8-1.81.8-1.81.8-1.91.71.7-1.61.01.5
Liver weight, right1.82.93.21.81.71.8-1.71.7-1.81.8-1.71.71.8-1.71.41.6
Locomotor activity2.33.67.0-2.7-2.2-2.02.0-2.02.0-2.02.1-1.8-1.71.5-0.4-1.4
Locomotor testing distance1.52.54.3-2.1-1.8-1.71.7-1.71.7-1.71.7-1.5-1.51.3-0.6-1.3
Locomotor testing rearing0.20.20.8-0.1-0.2-0.40.4-0.40.4-0.40.4-0.4-0.50.5-0.8-0.9
Locomotion in novel chamber0.40.50.8-0.6-0.8-0.70.6-0.60.7-0.70.7-0.8-0.90.9-0.7-0.1
Locomotion in novel chamber post-restriction1.01.23.1-1.0-0.9-1.01.0-1.01.2-1.21.0-1.0-1.11.0-1.1-1.8
Fecal boli incidents, locomotor time 11.21.32.11.51.21.2-1.11.1-1.11.1-1.11.11.0-1.00.61.4
Change in fecal boli incidents, locomotor task0.20.20.7-0.8-0.3-0.30.4-0.40.4-0.40.4-0.1-0.30.1-0.1-0.8
Time >=10cm from walls, locomotor time 10.60.61.70.40.60.7-0.70.7-0.70.7-0.70.90.8-1.01.30.9
Bouts of movement, locomotor time 10.20.20.3-0.4-0.4-0.50.5-0.50.5-0.50.5-0.5-0.50.5-0.5-0.5
Total resting periods, locomotor time 10.20.30.3-0.6-0.5-0.50.5-0.50.5-0.50.5-0.5-0.60.5-0.5-0.5
Rest time, locomotor task time 10.10.10.4-0.6-0.5-0.30.4-0.40.4-0.40.4-0.4-0.30.3-0.0-0.1
Distance moved, locomotor task time 10.80.81.70.60.80.8-0.90.9-0.90.9-0.91.01.0-1.11.30.7
Vertical activity count, locomotor time 10.10.10.30.20.30.2-0.10.1-0.10.1-0.10.2-0.1-0.0-0.5-0.5
Time >=10cm from walls, locomotor time 20.80.91.21.11.11.0-1.01.0-1.01.0-1.00.90.7-0.70.30.9
Bouts of movement, locomotor time 20.10.10.5-0.7-0.5-0.30.3-0.30.3-0.30.3-0.3-0.00.00.70.3
Total resting periods, locomotor time 20.10.10.6-0.7-0.5-0.30.2-0.20.2-0.20.2-0.20.0-0.00.80.3
Rest time, locomotor task time 20.30.40.7-0.8-0.7-0.70.6-0.60.6-0.60.6-0.5-0.40.40.2-0.6
Distance moved, locomotor task time 20.50.61.01.00.80.8-0.80.8-0.80.8-0.80.70.6-0.60.20.9
Vertical activity count, locomotor time 20.30.30.80.90.70.7-0.50.5-0.50.5-0.50.40.3-0.2-0.50.4
Light reinforcement 14.98.911.3-3.4-3.4-3.23.2-3.23.2-3.23.2-3.1-2.82.7-1.4-2.2
Light reinforcement 21.62.12.9-1.7-1.6-1.51.6-1.61.6-1.61.6-1.5-1.31.3-0.6-1.2
Bone: marrow area0.30.60.80.50.80.8-0.80.8-0.80.8-0.90.90.8-0.90.80.6
Bone: maximum diameter0.30.61.9-1.4-0.9-0.80.8-0.80.8-0.80.8-0.6-0.50.40.3-0.9
Bone: maximum force1.32.22.91.21.61.5-1.51.5-1.61.6-1.61.71.6-1.61.30.8
Bone: maximum moment1.11.82.41.11.51.4-1.41.4-1.41.4-1.41.51.4-1.51.20.6
Mean time between licks in bursts4.56.36.9-2.4-2.6-2.62.6-2.62.6-2.62.6-2.6-2.52.5-2.0-2.3
Mean num. licks in bursts0.10.10.20.10.30.3-0.30.3-0.30.3-0.30.30.3-0.40.40.1
Cd content in liver0.20.20.30.40.50.5-0.50.5-0.40.4-0.50.50.5-0.50.50.3
Co content in liver0.60.70.8-0.8-0.9-0.90.9-0.90.9-0.90.9-0.9-0.90.9-0.7-0.4
Cu content in liver0.40.51.40.10.40.5-0.60.6-0.60.6-0.60.70.8-0.81.20.9
Fe content in liver0.10.10.3-0.0-0.2-0.30.3-0.30.3-0.30.3-0.3-0.40.4-0.5-0.2
K content in liver0.30.31.4-0.20.10.3-0.40.4-0.30.3-0.30.40.5-0.61.21.1
Mg content in liver0.30.31.5-0.20.20.3-0.40.4-0.40.4-0.40.50.6-0.71.20.9
Mn content in liver0.30.41.8-1.3-0.7-0.50.4-0.40.4-0.40.4-0.10.1-0.21.20.3
Na content in liver1.92.04.70.91.11.2-1.41.4-1.31.3-1.31.31.5-1.41.72.2
Rb content in liver0.91.12.40.40.81.0-0.90.9-1.01.0-0.91.11.2-1.21.61.3
Se content in liver0.10.10.2-0.5-0.4-0.20.3-0.30.3-0.30.4-0.4-0.30.3-0.10.1
Sr content in liver0.20.20.90.1-0.2-0.20.2-0.20.2-0.20.3-0.4-0.50.6-0.9-0.3
Zn content in liver3.03.35.9-1.2-1.7-1.61.7-1.71.7-1.71.8-2.0-2.12.2-2.4-1.6
Bone: minimum diameter0.10.10.3-0.10.20.3-0.30.3-0.30.3-0.30.40.4-0.50.5-0.0
Time in familiar zone, hab. session 12.92.74.1-1.3-1.5-1.81.7-1.71.7-1.71.6-1.6-1.61.6-1.6-2.0
Time in novel zone, hab. session 11.71.72.40.81.11.4-1.31.3-1.31.3-1.21.31.3-1.41.51.4
Total zone transitions, hab. session 10.40.51.5-1.2-1.0-0.80.7-0.70.8-0.80.7-0.6-0.20.20.90.1
Total locomotion distance, hab. session 10.40.61.9-1.4-0.9-0.80.7-0.70.7-0.70.6-0.30.0-0.11.3-0.0
Locomotion velocity, hab. session 10.71.02.5-1.6-1.2-1.11.1-1.11.1-1.11.0-0.7-0.30.31.0-0.2
Time in familiar zone, hab. session 27.47.78.2-2.4-2.7-2.92.8-2.82.8-2.82.8-2.8-2.92.9-2.7-2.8
Time in novel zone, hab. session 25.65.66.32.02.32.5-2.42.4-2.42.4-2.42.52.5-2.52.32.2
Total zone transitions, hab. session 21.11.56.30.30.50.7-0.80.8-0.80.8-0.81.01.4-1.42.51.9
Total locomotion distance, hab. session 20.40.61.2-1.1-0.9-0.80.8-0.80.8-0.80.7-0.6-0.10.21.00.0
Locomotion velocity, hab. session 20.40.52.0-1.1-0.9-0.70.7-0.70.7-0.70.6-0.40.1-0.11.40.3
Novel to familiar place preference ratio5.55.76.51.82.22.4-2.42.4-2.42.4-2.32.52.5-2.52.52.4
Novelty place preference3.63.64.61.41.72.0-1.91.9-1.91.9-1.92.02.0-2.12.21.9
Time in novel zone, NPP test3.83.94.51.51.92.0-2.02.0-2.02.0-2.02.12.1-2.12.12.0
Total zone transitions, NPP test0.30.42.70.00.10.2-0.20.2-0.20.2-0.30.40.8-0.71.61.2
Total locomotion distance, NPP test0.40.63.00.10.30.3-0.40.4-0.40.4-0.50.60.9-0.91.71.1
Locomotion velocity, NPP test0.20.32.4-0.2-0.10.0-0.10.1-0.10.1-0.20.30.6-0.61.50.9
Intraocular pressure0.40.62.70.2-0.3-0.50.5-0.50.5-0.50.5-0.7-0.91.0-1.6-1.0
Delta distance traveled before/after self-admin1.81.92.8-1.4-1.4-1.51.5-1.51.5-1.51.4-1.3-1.21.2-0.8-1.7
Delta ambulatory time before/after self-admin1.61.82.4-1.5-1.4-1.51.4-1.41.4-1.41.4-1.3-1.21.1-0.7-1.5
Parametrial fat weight0.51.11.6-1.0-1.0-1.01.0-1.01.0-1.01.0-1.0-1.11.1-1.1-1.3
Pavlov. Cond. lever latency0.20.31.50.1-0.2-0.40.3-0.30.3-0.30.4-0.5-0.70.7-1.2-0.4
Pavlov. Cond. magazine entry latency3.03.84.2-1.9-2.0-2.02.0-2.02.0-2.02.0-2.0-1.91.9-1.4-2.0
Pavlov. Cond. change in total contacts0.00.00.1-0.2-0.2-0.10.2-0.20.2-0.20.2-0.2-0.10.10.1-0.2
Pavlov. Cond. index score0.20.30.6-0.7-0.6-0.50.6-0.60.6-0.60.5-0.4-0.30.20.3-0.6
Pavlov. Cond. latency score0.20.20.6-0.8-0.5-0.40.5-0.50.5-0.50.4-0.3-0.10.00.6-0.4
Pavlov. Cond. lever contacts0.20.21.6-0.30.00.3-0.20.2-0.10.1-0.20.40.6-0.61.30.2
Pavlov. Cond. magazine entry number0.60.81.10.90.90.9-0.90.9-1.01.0-0.90.90.8-0.80.51.1
Pavlov. Cond. intertrial magazine entries0.30.41.1-0.2-0.5-0.60.6-0.60.5-0.50.6-0.7-0.70.8-1.1-0.8
Pavlov. Cond. lever-magazine prob. diff.0.50.61.0-1.0-0.9-0.80.9-0.90.9-0.90.8-0.7-0.60.50.0-0.9
Pavlov. Cond. response bias1.01.21.5-1.1-1.2-1.11.2-1.21.2-1.21.1-1.1-1.01.0-0.6-1.2
Pavlov. Cond. lever latency1.01.32.91.21.01.1-1.21.2-1.11.1-1.11.01.1-1.01.01.7
Pavlov. Cond. magazine entry latency0.50.61.1-0.9-0.7-0.70.8-0.80.7-0.70.7-0.6-0.70.6-0.6-1.1
Pavlov. Cond. change in total contacts0.91.31.8-1.1-1.0-1.11.1-1.11.1-1.11.1-1.1-1.21.1-1.1-1.3
Pavlov. Cond. index score1.11.42.5-1.2-1.0-1.21.2-1.21.2-1.21.2-1.0-1.21.1-1.1-1.6
Pavlov. Cond. latency score0.91.22.2-1.2-1.0-1.11.1-1.11.1-1.11.1-0.9-1.00.9-0.9-1.5
Pavlov. Cond. lever contacts1.11.53.2-1.1-1.0-1.11.2-1.21.2-1.21.2-1.1-1.31.2-1.3-1.8
Pavlov. Cond. magazine entry number0.70.91.41.20.90.9-1.01.0-0.90.9-0.90.80.9-0.80.71.2
Pavlov. Cond. intertrial magazine entries0.10.20.50.70.50.4-0.40.4-0.50.5-0.40.30.2-0.2-0.30.3
Pavlov. Cond. lever-magazine prob. diff.1.01.32.2-1.2-1.0-1.11.2-1.21.1-1.11.1-1.0-1.11.0-0.9-1.5
Pavlov. Cond. response bias2.33.14.8-1.6-1.6-1.71.8-1.81.7-1.71.7-1.7-1.81.7-1.8-2.2
Time in closed arm before self-admin1.51.73.50.71.01.2-1.21.2-1.21.2-1.21.31.5-1.51.91.4
Time in closed arm after self-admin0.00.00.10.1-0.1-0.10.1-0.10.1-0.10.2-0.2-0.10.2-0.2-0.4
Time in open arm before self-admin0.91.01.5-1.0-1.1-0.90.9-0.90.9-0.91.0-1.1-1.21.1-1.1-0.3
Time in open arm after self-admin0.70.71.10.80.90.9-0.90.9-0.90.9-0.90.90.7-0.80.51.1
Bone: periosteal estimation0.61.21.80.51.01.1-1.01.0-1.11.1-1.11.21.2-1.31.40.6
Bone: periosteal perimeter0.00.10.5-0.5-0.00.0-0.00.0-0.00.0-0.00.20.2-0.40.7-0.2
Bone: post-yield work0.40.60.80.90.90.8-0.80.8-0.80.8-0.80.80.7-0.70.20.3
Progressive ratio test 1 active lever presses0.00.00.10.40.30.2-0.20.2-0.20.2-0.20.10.1-0.0-0.4-0.1
Progressive ratio test 1 breakpoint0.10.10.20.50.40.3-0.30.3-0.30.3-0.30.20.2-0.1-0.20.0
Progressive ratio test 1 inactive lever presses0.00.00.0-0.2-0.1-0.00.0-0.0-0.00.00.0-0.1-0.10.1-0.10.1
Progressive ratio test 2 active lever presses0.40.41.1-0.4-0.5-0.50.5-0.50.5-0.50.4-0.6-0.80.8-1.0-0.5
Progressive ratio test 2 breakpoint0.30.30.6-0.6-0.6-0.50.5-0.50.5-0.50.4-0.6-0.70.7-0.8-0.5
Progressive ratio test 2 inactive lever presses0.00.00.1-0.3-0.2-0.20.2-0.20.1-0.10.0-0.2-0.20.1-0.10.1
Incentive Sensitization - Responses0.40.41.1-0.5-0.6-0.40.4-0.40.4-0.40.4-0.7-0.90.8-1.1-0.2
Incentive Sensitization - Breakpoint0.40.41.0-0.5-0.6-0.50.5-0.50.5-0.50.4-0.7-0.90.8-1.0-0.3
Sum of active levers in priming session hrs 5-60.00.00.4-0.2-0.10.0-0.00.0-0.00.0-0.1-0.0-0.00.00.00.6
Progressive ratio0.10.10.50.70.40.3-0.30.3-0.30.3-0.40.30.3-0.20.20.5
Food seeking constrained by brief footshock0.10.10.2-0.3-0.4-0.30.3-0.30.4-0.40.2-0.3-0.10.20.30.3
Seeking ratio, punishment vs. effort0.10.10.3-0.5-0.4-0.30.2-0.20.3-0.30.3-0.3-0.20.10.2-0.0
Retroperitoneal fat weight0.20.71.31.11.00.9-0.90.9-0.90.9-0.90.90.9-0.80.40.5
Reaction time number correct0.30.41.11.10.70.6-0.60.6-0.60.6-0.60.30.1-0.0-1.0-0.0
Reaction time mean minus median0.81.01.2-1.0-1.0-1.01.0-1.01.0-1.01.0-1.0-1.11.0-1.1-1.0
Reaction time mean minus median AUC0.10.10.5-0.20.20.1-0.20.2-0.20.2-0.20.40.3-0.50.70.4
Reaction time num false alarms0.10.11.00.20.30.2-0.10.1-0.10.1-0.10.0-0.30.3-1.0-0.6
Reaction time num false alarms AUC0.10.21.30.40.30.2-0.20.2-0.20.2-0.2-0.0-0.30.3-1.1-0.5
Reaction time trials correct on left0.30.41.11.10.70.6-0.60.6-0.60.6-0.60.30.1-0.0-1.0-0.0
Reaction time trials on left0.30.41.11.10.70.7-0.70.7-0.60.6-0.60.40.1-0.1-0.90.0
Reaction time mean0.00.10.2-0.10.20.0-0.10.1-0.20.2-0.20.30.3-0.40.40.1
Reaction time mean AUC0.10.10.3-0.00.30.1-0.20.2-0.30.3-0.30.40.4-0.50.50.1
Median of all reaction times0.40.50.90.40.70.6-0.70.7-0.70.7-0.70.80.8-0.90.90.6
Reaction time omissions0.10.20.5-0.7-0.6-0.40.4-0.40.4-0.40.5-0.5-0.40.40.00.0
Reaction time false alarm rate0.00.00.00.00.10.1-0.10.1-0.10.1-0.10.1-0.0-0.0-0.2-0.2
Reaction time premature initiation rate1.62.13.3-1.2-1.3-1.41.5-1.51.5-1.51.4-1.4-1.51.5-1.5-1.8
Reaction time premature initiations1.42.04.3-0.7-1.0-1.21.3-1.31.3-1.31.2-1.4-1.51.6-2.1-1.9
Std. dev. reaction times0.20.20.3-0.6-0.5-0.50.5-0.50.5-0.50.5-0.4-0.50.4-0.4-0.5
Reaction time trials completed0.30.41.11.10.70.7-0.70.7-0.60.6-0.60.40.1-0.1-0.90.0
Reaction time trials AUC0.20.41.31.00.70.6-0.60.6-0.50.5-0.50.2-0.00.1-1.2-0.1
Run reversals in cocaine runway, females0.20.20.5-0.7-0.6-0.50.5-0.50.5-0.50.4-0.4-0.40.4-0.2-0.4
Run reversals in cocaine runway, males1.01.01.3-1.1-1.1-1.01.0-1.01.1-1.11.0-0.9-0.80.8-0.3-1.1
Latency to leave start box in cocaine runway0.40.41.9-1.4-0.9-0.70.7-0.70.5-0.50.6-0.5-0.50.30.40.0
Latency to leave start box in cocaine runway, F0.50.52.4-0.40.20.4-0.50.5-0.50.5-0.50.60.7-0.91.51.1
Latency to leave start box in cocaine runway, M3.73.54.3-1.6-1.8-1.91.9-1.91.7-1.71.9-2.0-2.12.1-2.0-1.6
Std. dev. time between licks in bursts0.50.61.4-1.2-0.8-0.90.8-0.80.8-0.80.7-0.6-0.70.5-0.3-0.7
Total sessions with >9 infusions0.10.10.3-0.10.10.3-0.30.3-0.30.3-0.10.20.2-0.20.30.5
Short access day 1 total inactive lever presses0.00.00.2-0.2-0.3-0.10.1-0.10.0-0.00.2-0.3-0.10.2-0.10.4
Short access day 10 total inactive lever presses0.10.10.2-0.3-0.3-0.20.2-0.20.1-0.10.2-0.3-0.50.4-0.40.3
Short access day 1 total infusions0.00.10.2-0.4-0.3-0.20.2-0.20.1-0.10.3-0.10.1-0.10.40.1
Short access day 10 total infusions0.10.10.4-0.1-0.1-0.10.1-0.10.1-0.10.1-0.2-0.30.3-0.6-0.2
Short access total infusions0.00.00.0-0.00.00.1-0.10.1-0.10.1-0.00.00.1-0.10.00.2
Short access day 1 locomotion0.60.71.6-1.3-0.9-0.90.9-0.90.8-0.80.9-0.8-0.70.6-0.3-0.6
Short access day 10 total locomotion3.94.45.6-2.2-2.3-2.02.0-2.02.0-2.02.2-2.3-2.42.3-2.0-1.3
Short access total locomotion0.70.71.3-1.1-1.0-0.80.8-0.80.8-0.81.0-0.9-1.00.9-0.7-0.4
One hour access (0.3 mA shock)0.10.20.30.40.50.4-0.40.4-0.40.4-0.60.40.4-0.30.10.3
Compulsive drug intake1.71.72.61.01.21.3-1.31.3-1.31.3-1.21.31.3-1.31.31.6
One hour access (shock baseline)0.20.30.9-0.2-0.3-0.40.4-0.40.4-0.40.3-0.5-0.50.6-0.9-0.8
Social response proportion0.40.50.7-0.8-0.8-0.80.8-0.80.8-0.80.7-0.6-0.30.40.3-0.6
Social responses5.67.210.6-3.3-2.9-2.92.8-2.82.9-2.92.8-2.6-2.52.3-1.3-2.4
Social time0.60.81.61.00.80.7-0.80.8-0.80.8-0.80.80.9-0.80.91.3
Soleus weight8.424.528.75.45.45.3-5.25.2-5.25.2-5.25.04.8-4.73.04.2
Bone: stiffness3.14.85.72.12.42.3-2.32.3-2.32.3-2.32.42.3-2.31.71.6
Tibialis anterior weight1.13.84.91.92.12.2-2.12.1-2.12.1-2.12.01.8-1.81.21.9
Time to tail flick, vehicle, before self-admin0.10.10.6-0.8-0.5-0.30.4-0.40.4-0.40.3-0.3-0.10.10.50.1
Time to tail flick, vehicle, after self-admin0.50.51.50.0-0.4-0.60.6-0.60.6-0.60.6-0.7-0.70.8-1.2-1.0
Time to tail flick, test, before self-admin0.10.10.4-0.3-0.3-0.20.2-0.20.2-0.20.2-0.10.1-0.20.6-0.0
Time to tail flick, test, after self-admin0.10.10.2-0.2-0.4-0.30.3-0.30.3-0.30.3-0.3-0.10.10.2-0.4
Delta time to tail flick, vehicle, before/after SA0.20.21.00.90.50.1-0.20.2-0.20.2-0.20.1-0.10.2-1.0-0.5
Delta time to tail flick, test, before/after SA0.30.30.7-0.1-0.4-0.50.5-0.50.5-0.50.5-0.6-0.60.7-0.9-0.7
Tibia length1.02.73.4-1.6-1.7-1.81.8-1.81.7-1.71.7-1.7-1.61.6-1.3-1.4
Ambulatory time before self-admin0.60.61.80.40.60.8-0.80.8-0.80.8-0.70.70.6-0.70.71.3
Ambulatory time after self-admin0.30.30.9-0.9-0.7-0.50.5-0.50.5-0.50.6-0.5-0.60.5-0.1-0.0
Bone: tissue strength1.81.71.91.21.31.3-1.31.3-1.31.3-1.31.41.4-1.41.21.2
Total heroin consumption1.72.03.2-1.8-1.6-1.41.5-1.51.5-1.51.4-1.5-1.41.4-1.0-0.9
Bone: trabecular number0.20.31.3-1.1-0.7-0.50.5-0.50.6-0.60.6-0.3-0.20.10.7-0.1
Bone: trabecular spacing0.30.32.70.90.40.0-0.10.1-0.10.1-0.1-0.2-0.50.6-1.6-0.4
Bone: trabecular thickness1.21.46.9-0.50.40.8-0.70.7-0.80.8-0.71.11.4-1.52.61.4
Bone: trabecular tissue density1.21.72.91.71.41.3-1.31.3-1.31.3-1.41.21.2-1.10.61.3
Water consumed over 24 hours0.81.01.30.61.01.0-1.01.0-1.01.0-1.01.11.1-1.11.10.7
Number of responses in last shaping day0.10.10.3-0.5-0.4-0.30.3-0.30.2-0.20.3-0.4-0.40.4-0.5-0.1