Hub : Genes

Sf3a2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Sf3a2 0.1 0.08 6.8e-06 0.07 0.08 0.09 0.08 1.0e-04 6.8e-05 1.3e-05 5.2e-05
2 NAcc mRNA stability Sf3a2 0.06 0.05 6.2e-09 0.04 0.05 0.05 0.05 4.8e-07 1.4e-08 1.3e-07 4.0e-08
3 Brain mRNA stability Sf3a2 0.1 0.06 1.2e-10 0.11 0.1 0.1 0.1 1.9e-10 3.0e-09 2.8e-09 1.5e-09
4 Brain intron excision ratio chr7_9563765_9566161 0.03 0.02 4.7e-03 0.01 0.02 0.01 0.01 2.0e-02 9.8e-03 7.5e-02 3.8e-02
5 Adipose gene expression Sf3a2 0.04 0.03 6.8e-06 0.04 0.04 0.04 0.04 8.7e-06 1.7e-05 1.4e-05 9.2e-06
6 PL mRNA stability Sf3a2 0.11 0.07 9.8e-15 0.14 0.14 0.14 0.14 8.0e-15 4.4e-15 1.3e-14 3.4e-15
7 Brain gene expression Sf3a2 0.11 0.06 2.5e-12 0.12 0.12 0.13 0.12 1.5e-11 1.8e-11 8.0e-12 1.3e-11
8 IC gene expression Sf3a2 0.08 0.06 1.9e-03 0.04 0.03 0.01 0.02 8.1e-03 2.7e-02 1.5e-01 4.8e-02
9 LHb mRNA stability Sf3a2 0.13 0.1 4.1e-03 0.1 0.1 0.09 0.09 2.5e-03 2.0e-03 3.1e-03 3.9e-03
10 PL gene expression Sf3a2 0.04 0.03 2.0e-05 0.04 0.04 0.04 0.04 1.3e-05 1.1e-05 3.2e-05 2.1e-05
11 Liver mRNA stability Sf3a2 0.02 0.02 9.1e-03 0 0.01 0 0 1.3e-01 2.1e-02 7.3e-02 1.2e-01
12 NAcc intron excision ratio chr7_9563765_9566161 0.01 0.01 9.5e-03 0.01 0.01 0.01 0.01 1.8e-02 4.3e-03 2.6e-03 3.8e-03
13 NAcc gene expression Sf3a2 0.03 0.02 8.7e-05 0.02 0.02 0.02 0.01 4.8e-04 7.5e-04 3.5e-04 1.8e-03
14 pVTA mRNA stability Sf3a2 0.04 0.04 2.3e-03 0 0.01 0.01 0.01 2.9e-01 5.9e-02 2.3e-02 7.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.61.13.2-0.10.2-0.7-0.50.70.80.70.71.1-1.31.51.81.7-1.3
Area under the delay curve1.52.33.0-1.61.6-1.7-1.61.61.51.51.71.6-1.51.51.01.2-1.7
BMI with tail5.117.925.2-5.04.9-4.6-4.84.64.44.74.64.2-3.93.63.13.3-2.4
BMI without tail0.84.37.0-2.62.6-2.3-2.42.32.22.42.22.0-1.81.61.11.2-1.5
Body weight0.73.24.4-2.12.0-2.0-2.02.01.92.01.91.8-1.71.51.41.4-0.8
Weight adjusted by age0.10.20.4-0.70.7-0.4-0.50.50.40.50.40.2-0.10.00.1-0.0-0.3
Bone surface0.61.23.80.6-0.4-0.30.00.40.60.30.31.0-1.31.61.91.8-1.6
Bone volume0.61.23.60.6-0.4-0.3-0.00.40.60.30.31.1-1.41.71.91.8-1.7
Breakpoint value in progressive ratio session2.74.96.32.2-2.22.32.2-2.2-2.4-2.2-2.1-2.22.2-2.1-2.5-2.21.9
Number of licking bursts0.10.20.6-0.20.10.20.1-0.2-0.3-0.2-0.2-0.50.6-0.7-0.8-0.80.7
Context. condit. distance diff. score0.30.30.5-0.70.7-0.6-0.70.60.50.70.60.6-0.50.50.20.3-0.7
Locomotion velocity, session 10.20.20.80.9-0.70.40.5-0.5-0.0-0.4-0.4-0.1-0.10.20.40.4-0.2
Locomotion distance, session 10.40.52.40.5-0.4-0.10.10.10.30.10.10.6-0.80.91.51.4-0.1
Locomotion velocity, session 21.62.05.02.2-2.11.51.8-1.6-1.4-1.7-1.5-1.10.8-0.50.1-0.00.9
Locomotion distance, session 20.71.02.71.6-1.61.01.2-1.0-0.8-1.1-1.0-0.50.20.00.80.70.8
Locomotion velocity, session 35.56.37.42.7-2.72.62.7-2.7-2.5-2.7-2.6-2.62.5-2.4-2.2-2.31.9
Locomotion distance, session 30.00.00.10.00.00.00.0-0.1-0.2-0.0-0.0-0.10.2-0.2-0.4-0.3-0.1
Stereotopy head waving bouts, day 33.44.06.12.4-2.52.22.3-2.2-2.0-2.4-2.2-1.91.7-1.6-1.1-1.21.6
Stereotopy head waving duration, day 34.45.47.72.7-2.72.52.7-2.5-2.4-2.8-2.5-2.32.1-2.0-1.5-1.71.8
Locomotion velocity, session 70.50.60.80.9-0.70.80.8-0.8-0.9-0.7-0.8-0.70.7-0.6-0.9-0.9-0.6
Locomotion distance, session 70.10.10.5-0.40.4-0.1-0.30.1-0.30.20.1-0.10.2-0.3-0.7-0.6-0.1
Stereotopy head waving bouts, day 70.30.41.0-0.00.1-0.4-0.20.40.50.20.40.7-0.80.91.01.0-0.9
Stereotopy head waving duration, day 70.10.20.50.6-0.50.20.4-0.20.0-0.3-0.20.2-0.30.50.70.6-0.6
Locomotion velocity, session 80.20.30.90.8-0.70.30.5-0.3-0.3-0.4-0.30.1-0.30.51.00.8-0.4
Locomotion distance, session 80.10.10.20.4-0.40.20.3-0.2-0.1-0.2-0.2-0.0-0.10.20.40.40.1
Degree of sensitization distance0.40.40.5-0.70.7-0.7-0.70.70.50.70.70.6-0.60.60.50.5-0.6
Degree of sensitization stereotypy2.22.53.0-1.31.4-1.6-1.51.51.61.51.61.7-1.71.71.61.7-1.7
Conditioned locomotion0.50.61.8-1.31.2-0.9-1.11.00.80.90.90.5-0.40.2-0.1-0.0-0.1
Cocaine response after cond. corrected2.33.56.9-2.62.6-2.1-2.32.11.92.12.11.6-1.41.10.40.7-1.3
Cocaine response after cond. not corrected2.53.67.4-2.72.6-2.2-2.42.22.02.22.21.6-1.41.10.40.6-1.2
Cocaine response before conditioning0.30.40.60.8-0.80.70.7-0.7-0.6-0.7-0.7-0.60.5-0.4-0.6-0.60.2
Saline control response0.10.10.2-0.40.4-0.2-0.30.10.20.20.20.10.0-0.1-0.5-0.30.3
Bone: connectivity density0.81.32.9-0.50.6-1.0-0.81.01.00.91.01.2-1.41.51.71.6-1.2
Bone: cortical apparent density0.71.11.5-1.11.1-1.1-1.11.11.21.11.11.1-1.11.00.70.8-0.9
Bone: cortical area0.81.32.5-0.60.8-1.0-0.91.01.21.01.01.2-1.31.41.31.3-1.6
Bone: cortical porosity0.10.10.20.5-0.40.20.3-0.2-0.1-0.2-0.2-0.0-0.10.20.50.4-0.2
Bone: cortical porosity0.30.31.20.2-0.1-0.2-0.10.20.40.20.20.5-0.60.81.11.0-0.6
Bone: cortical thickness1.32.12.6-1.21.3-1.5-1.41.41.61.51.51.6-1.61.61.51.5-1.4
Bone: cortical thickness0.30.31.00.1-0.10.40.3-0.4-0.4-0.4-0.4-0.60.7-0.8-1.0-1.00.3
Bone: cortical tissue density0.50.71.0-0.90.9-0.9-0.90.91.00.90.90.9-0.90.80.60.7-0.8
Condit. Reinf. active minus inactive responses3.54.05.12.3-2.22.12.2-2.2-2.0-2.2-2.1-2.01.9-1.8-1.5-1.61.6
Condit. Reinf. active-inactive response ratio2.52.73.01.5-1.51.61.6-1.7-1.6-1.6-1.6-1.71.7-1.7-1.7-1.71.4
Condit. Reinf. active responses2.22.95.12.3-2.21.92.0-1.9-1.6-2.0-1.9-1.61.4-1.2-0.7-0.81.4
Condit. Reinf. inactive responses0.30.41.21.1-1.00.60.8-0.6-0.4-0.6-0.6-0.20.00.10.70.50.3
Incentive salience index mean1.31.73.01.7-1.71.41.6-1.5-1.3-1.5-1.4-1.21.0-0.9-0.5-0.61.1
Condit. Reinf. lever presses0.30.52.10.2-0.2-0.3-0.10.20.40.30.30.7-0.91.01.51.4-0.2
Condit. Reinf. active minus inactive responses2.53.84.71.7-1.81.91.9-2.1-2.0-1.9-1.9-2.12.1-2.1-2.2-2.11.5
Condit. Reinf. active-inactive response ratio0.40.71.40.2-0.30.60.5-0.7-0.7-0.6-0.6-0.91.0-1.1-1.1-1.11.2
Condit. Reinf. active responses2.43.44.11.9-1.81.91.9-2.0-1.9-1.9-1.9-1.91.9-1.8-2.0-1.91.0
Condit. Reinf. inactive responses0.81.21.81.3-1.21.21.2-1.2-1.1-1.2-1.2-1.01.0-0.9-1.3-1.20.1
Condit. Reinf. lever presses2.13.14.31.6-1.61.81.7-1.8-1.8-1.8-1.8-1.81.8-1.8-2.1-2.01.1
Condit. Reinf. lever reinforcers received2.13.04.51.6-1.51.71.7-1.8-1.8-1.7-1.7-1.81.8-1.8-2.1-2.01.0
Conditioned reinforcement - actives0.62.23.01.3-1.31.61.4-1.5-1.6-1.2-1.5-1.61.7-1.7-1.3-1.51.3
Conditioned reinforcement - inactives0.00.00.1-0.20.10.1-0.0-0.1-0.10.10.0-0.20.2-0.3-0.2-0.20.2
Conditioned locomotion6.19.111.63.4-3.33.33.3-3.4-3.3-3.0-3.1-3.02.9-2.7-2.4-2.42.1
Patch foraging indifference point 0 sec0.10.40.5-0.50.5-0.5-0.60.60.70.60.50.7-0.70.70.60.6-0.7
Patch foraging indifference point AUC0.61.52.11.2-1.21.21.2-1.3-1.3-1.2-1.2-1.31.2-1.2-1.0-1.01.5
Delay disc. indifference point, 0s delay9.710.913.4-2.92.9-3.2-3.13.23.33.33.33.5-3.63.63.73.6-3.0
Delay disc. indifference point, 16s delay0.20.20.6-0.50.5-0.6-0.50.50.50.40.50.5-0.50.50.20.4-0.7
Delay disc. indifference point, 2s delay6.77.58.4-2.72.7-2.8-2.82.82.82.82.82.9-2.82.82.22.4-2.9
Delay disc. indifference point, 24s delay0.30.40.7-0.80.8-0.9-0.70.70.50.70.70.5-0.50.40.10.3-0.8
Delay disc. indifference point, 4s delay1.92.04.2-1.31.3-1.5-1.31.41.41.21.41.5-1.51.51.11.3-2.1
Delay disc. indifference point, 8s delay0.50.91.5-1.21.2-1.1-1.11.00.91.01.10.9-0.80.70.40.5-0.8
Indifference point function ln k0.10.21.1-0.50.5-0.4-0.40.40.40.40.40.3-0.30.3-0.10.0-1.0
Indifference point function log k0.10.21.1-0.50.5-0.4-0.40.40.40.40.40.3-0.30.3-0.10.0-1.0
Patch foraging total patch changes 0 sec0.10.30.4-0.50.5-0.5-0.50.60.60.50.50.6-0.60.60.50.5-0.6
Patch foraging total patch changes 12 sec0.20.20.5-0.70.6-0.5-0.60.40.50.50.50.3-0.20.10.10.20.4
Patch foraging total patch changes 18 sec0.41.01.31.1-1.11.11.1-1.1-1.0-1.1-1.1-1.00.9-0.8-0.6-0.80.9
Patch foraging total patch changes 24 sec0.00.10.30.3-0.30.30.3-0.2-0.2-0.2-0.3-0.20.2-0.1-0.2-0.20.5
Patch foraging total patch changes 6 sec0.10.20.40.6-0.60.50.5-0.5-0.3-0.4-0.5-0.30.3-0.20.20.00.5
Patch foraging time to switch 0 sec1.03.76.5-1.31.4-1.9-1.61.82.11.71.72.1-2.22.22.52.5-1.2
Patch foraging water rate 0 sec0.20.72.40.0-0.00.60.3-0.6-0.8-0.4-0.5-0.91.1-1.2-1.5-1.40.3
Patch foraging water rate 12 sec0.10.51.8-1.31.2-0.7-1.00.70.50.80.80.3-0.1-0.1-0.6-0.5-0.3
Patch foraging water rate 18 sec1.02.27.20.0-0.21.10.6-1.0-1.2-0.9-0.9-1.61.8-2.1-2.7-2.51.3
Patch foraging water rate 24 sec0.50.72.6-0.80.60.1-0.3-0.2-0.30.00.0-0.70.9-1.2-1.6-1.50.7
Patch foraging water rate 6 sec1.21.84.90.6-0.61.10.9-1.1-1.3-1.1-1.1-1.51.6-1.7-2.2-2.10.8
Seeking ratio, delayed vs. immediate footshock2.84.05.62.4-2.32.12.2-2.2-2.3-2.1-2.1-1.91.7-1.6-1.9-1.71.0
Distance traveled before self-admin0.10.20.6-0.20.3-0.4-0.40.20.30.60.60.5-0.50.50.30.5-0.8
Distance traveled after self-admin0.00.00.10.2-0.20.10.2-0.3-0.2-0.0-0.1-0.10.1-0.1-0.3-0.1-0.1
Extensor digitorum longus weight3.011.818.3-4.34.3-3.9-4.13.73.53.93.93.3-3.02.71.92.3-2.3
Bone: elastic displacement0.10.20.30.5-0.50.40.5-0.4-0.5-0.4-0.4-0.40.4-0.3-0.1-0.20.2
Bone: elastic work0.40.51.6-0.50.6-0.7-0.60.70.70.70.70.7-0.80.80.60.6-1.3
Bone: endosteal estimation0.20.61.1-0.60.7-0.7-0.70.70.80.70.70.8-0.80.90.70.8-1.0
Bone: endosteal perimeter0.10.20.70.8-0.70.50.6-0.5-0.4-0.6-0.5-0.30.2-0.10.0-0.0-0.4
Epididymis fat weight0.10.31.0-0.20.10.30.1-0.2-0.3-0.3-0.1-0.50.6-0.8-1.0-0.91.0
Delta time in closed arm before/after self-admin0.40.41.5-0.80.7-0.1-0.40.20.00.30.2-0.30.6-0.8-1.2-1.00.7
Delta time in open arm before/after self-admin0.50.60.9-0.80.8-0.9-0.80.80.80.70.90.8-0.80.70.70.7-0.6
Diff in mean of infusions in LGA sessions1.01.82.31.5-1.41.31.4-1.3-1.5-1.5-1.2-1.31.2-1.1-1.4-1.21.2
Delay discount exponential model param1.41.92.61.5-1.51.61.5-1.4-1.3-1.3-1.5-1.41.3-1.3-0.8-1.01.6
Extinction: sum of active levers before priming1.11.62.40.9-1.11.41.1-1.3-1.2-1.1-1.2-1.31.4-1.4-1.6-1.41.5
Active lever presses in extinction session 62.02.03.01.7-1.71.71.6-1.6-1.6-1.4-1.5-1.41.3-1.2-1.1-0.90.8
Bone: final force1.72.84.0-1.31.5-1.6-1.51.61.81.61.61.8-1.81.91.61.7-2.0
Bone: final moment1.42.33.4-1.11.3-1.5-1.41.41.61.51.51.6-1.71.71.51.5-1.8
Food consumed during 24 hour testing period0.20.50.8-0.90.9-0.8-0.80.80.70.80.80.7-0.60.60.10.3-0.8
Glucose2.03.24.4-2.02.1-2.0-2.01.81.82.02.01.8-1.61.51.11.3-1.6
Heart weight1.01.63.00.7-0.81.11.0-1.1-1.2-1.2-1.1-1.41.5-1.5-1.7-1.61.2
Delay discount hyperbolic model param2.73.44.71.9-2.02.01.9-1.9-1.9-1.8-2.0-1.91.8-1.8-1.2-1.52.2
Intermittent access intake day 1-15 change1.47.78.62.6-2.72.92.8-2.9-2.9-2.7-2.9-2.92.9-2.9-2.6-2.72.3
Intermittent access intake escalation1.26.87.62.5-2.52.72.6-2.7-2.8-2.6-2.7-2.72.7-2.7-2.5-2.52.2
Intermittent access intake escalation 23.45.86.52.4-2.42.52.4-2.5-2.5-2.4-2.5-2.52.5-2.4-2.3-2.41.9
Intermitt. access day 1 inactive lever presses0.11.02.70.4-0.40.80.6-0.9-1.1-0.6-0.7-1.11.3-1.4-1.6-1.30.9
Intermitt. access day 15 inactive lever presses0.10.30.50.7-0.70.60.6-0.6-0.6-0.6-0.6-0.50.5-0.5-0.2-0.30.5
Intermitt. access escalation Index0.51.63.0-0.90.9-1.2-1.11.11.21.21.11.4-1.41.51.71.5-1.3
Intermittent access day 1 total infusions0.10.40.70.3-0.30.60.5-0.6-0.6-0.5-0.4-0.70.8-0.8-0.8-0.80.3
Intermittent access day 15 total infusions1.74.15.01.9-2.02.22.1-2.1-2.2-2.0-2.0-2.22.2-2.1-2.0-2.01.4
Intermittent access terminal intake (last 3 days)1.52.73.51.6-1.61.91.7-1.7-1.8-1.6-1.6-1.71.7-1.7-1.5-1.61.0
Intermittent access total infusions1.11.41.81.1-1.11.41.2-1.3-1.3-1.1-1.1-1.31.3-1.3-1.0-1.10.7
Intermittent access day 1 locomotion1.52.73.51.3-1.31.71.5-1.6-1.7-1.5-1.5-1.81.8-1.9-1.9-1.81.5
Intermittent access day 15 total locomotion1.66.37.22.4-2.42.62.5-2.7-2.7-2.4-2.5-2.72.7-2.6-2.1-2.22.5
Intermittent access total locomotion2.93.54.11.7-1.82.01.9-2.0-2.0-1.7-1.8-2.02.0-2.0-1.8-1.81.7
Intermittent access standard deviation1.47.29.03.0-2.93.02.9-3.0-2.9-2.7-2.8-2.82.7-2.5-2.1-2.11.8
Left kidney weight0.00.20.7-0.10.10.20.0-0.2-0.3-0.1-0.2-0.40.5-0.6-0.9-0.80.4
Right kidney weight0.42.94.41.4-1.31.71.5-1.6-1.7-1.6-1.6-1.81.9-1.9-2.1-2.11.3
Cocaine induced anxiety0.30.71.91.4-1.30.91.1-0.9-0.8-0.9-1.0-0.60.4-0.30.1-0.00.6
Post-drug Anxiety0.40.51.51.2-1.10.70.9-0.7-0.6-0.9-0.7-0.40.2-0.00.00.10.3
Baseline Anxiety0.10.10.60.3-0.20.30.3-0.3-0.3-0.3-0.1-0.30.3-0.3-0.8-0.5-0.2
Tail length2.412.614.73.8-3.73.83.8-3.8-3.7-3.7-3.8-3.63.5-3.4-3.2-3.42.0
Length with tail1.87.99.23.0-3.03.03.0-3.0-2.9-3.0-3.0-2.92.8-2.7-2.4-2.62.1
Length without tail0.00.00.0-0.10.1-0.0-0.10.0-0.00.10.10.0-0.0-0.0-0.0-0.00.1
Times rat made contact with spout0.10.10.2-0.50.5-0.2-0.30.20.20.20.20.00.1-0.1-0.4-0.30.1
Lifetime Intake0.60.81.20.8-0.81.10.9-1.0-1.0-0.8-0.8-1.01.0-1.0-0.8-0.80.5
Liver weight, left0.71.32.0-1.41.3-1.2-1.31.21.21.21.31.1-1.00.90.70.8-0.7
Liver weight, right0.30.61.1-1.01.0-0.8-0.90.80.70.90.90.7-0.50.50.00.2-0.7
Locomotor activity2.03.15.82.4-2.32.02.2-2.0-1.9-2.0-2.0-1.61.4-1.1-1.0-1.10.9
Locomotor testing distance0.82.03.71.9-1.91.61.7-1.6-1.5-1.5-1.6-1.21.1-0.9-1.0-0.90.6
Locomotor testing rearing0.10.20.90.1-0.20.30.3-0.4-0.3-0.4-0.3-0.40.5-0.5-0.9-0.80.1
Locomotion in novel chamber1.41.93.11.2-1.31.31.3-1.4-1.4-1.2-1.3-1.41.4-1.4-1.4-1.21.8
Locomotion in novel chamber post-restriction0.61.83.41.3-1.31.31.4-1.3-1.2-1.4-1.4-1.31.3-1.3-1.9-1.70.4
Fecal boli incidents, locomotor time 10.51.32.1-1.21.3-1.2-1.31.21.31.41.31.1-1.00.90.80.90.3
Change in fecal boli incidents, locomotor task0.30.32.60.6-0.50.50.5-0.4-0.4-0.3-0.4-0.20.10.0-0.2-0.3-1.6
Time >=10cm from walls, locomotor time 10.60.81.9-0.30.5-0.7-0.60.50.70.90.60.9-1.01.11.41.3-1.0
Bouts of movement, locomotor time 10.30.40.50.6-0.60.70.6-0.7-0.7-0.6-0.7-0.70.7-0.7-0.5-0.60.5
Total resting periods, locomotor time 10.40.40.60.7-0.70.70.7-0.8-0.7-0.7-0.7-0.70.7-0.7-0.6-0.60.3
Rest time, locomotor task time 10.10.20.40.7-0.50.50.5-0.6-0.4-0.3-0.4-0.30.3-0.2-0.1-0.20.0
Distance moved, locomotor task time 10.51.53.2-0.90.8-1.1-1.01.11.11.11.01.3-1.41.41.61.5-1.8
Vertical activity count, locomotor time 10.00.21.0-0.50.5-0.3-0.40.30.30.40.30.2-0.20.2-0.2-0.1-1.0
Time >=10cm from walls, locomotor time 20.20.71.2-1.11.1-0.9-1.10.80.91.10.90.8-0.70.60.20.4-0.6
Bouts of movement, locomotor time 20.10.20.70.7-0.60.30.4-0.4-0.2-0.4-0.3-0.1-0.00.20.90.60.2
Total resting periods, locomotor time 20.10.21.00.6-0.50.20.4-0.3-0.2-0.4-0.30.0-0.10.31.00.80.1
Rest time, locomotor task time 20.20.40.80.9-0.90.60.8-0.7-0.6-0.7-0.7-0.50.4-0.30.0-0.10.3
Distance moved, locomotor task time 20.30.50.9-1.00.9-0.7-0.80.70.70.80.70.6-0.50.40.50.5-0.1
Vertical activity count, locomotor time 20.10.20.6-0.80.8-0.5-0.70.50.50.60.50.2-0.1-0.0-0.2-0.20.2
Light reinforcement 11.77.711.33.4-3.32.93.2-3.0-2.9-3.1-3.1-2.62.4-2.2-1.8-2.02.3
Light reinforcement 20.81.93.01.7-1.71.51.6-1.5-1.4-1.5-1.5-1.31.2-1.0-0.8-0.91.0
Bone: marrow area0.20.61.0-0.60.7-0.7-0.70.70.80.70.70.8-0.80.90.70.7-1.0
Bone: maximum diameter0.40.72.01.4-1.31.01.1-1.0-0.8-1.0-1.0-0.60.5-0.3-0.2-0.2-0.1
Bone: maximum force1.42.74.0-1.41.5-1.6-1.61.61.81.61.61.7-1.71.81.41.5-2.0
Bone: maximum moment1.22.33.4-1.21.4-1.5-1.51.51.71.51.51.6-1.61.61.31.4-1.8
Mean time between licks in bursts1.06.06.82.5-2.62.62.6-2.6-2.6-2.6-2.6-2.52.4-2.4-1.9-2.12.3
Mean num. licks in bursts0.10.10.4-0.10.2-0.3-0.30.30.40.30.30.4-0.40.50.30.4-0.6
Cd content in liver0.10.20.30.5-0.50.40.5-0.4-0.4-0.4-0.4-0.30.3-0.3-0.2-0.20.4
Co content in liver1.82.12.41.4-1.51.51.5-1.5-1.6-1.5-1.5-1.51.5-1.5-1.3-1.41.3
Cu content in liver0.10.10.40.6-0.50.20.3-0.3-0.2-0.2-0.20.0-0.20.30.60.5-0.2
Fe content in liver0.20.30.50.3-0.40.50.4-0.5-0.5-0.5-0.5-0.60.6-0.6-0.4-0.40.7
K content in liver0.10.10.40.2-0.2-0.10.00.00.10.10.10.3-0.40.50.70.6-0.1
Mg content in liver0.20.20.40.6-0.60.50.5-0.5-0.5-0.5-0.5-0.30.2-0.20.0-0.00.3
Mn content in liver0.60.62.01.4-1.20.81.0-0.8-0.7-0.8-0.8-0.30.10.10.70.4-0.5
Na content in liver1.41.63.1-0.90.9-1.2-1.11.11.21.21.21.3-1.41.51.81.7-0.8
Rb content in liver0.20.20.70.2-0.1-0.2-0.10.20.30.20.20.5-0.60.80.90.8-0.7
Se content in liver0.20.20.30.5-0.50.50.5-0.5-0.5-0.5-0.5-0.50.5-0.5-0.2-0.30.6
Sr content in liver0.00.00.1-0.10.10.0-0.0-0.0-0.1-0.0-0.0-0.10.2-0.2-0.3-0.30.2
Zn content in liver5.66.68.22.1-2.12.42.3-2.5-2.6-2.5-2.4-2.72.8-2.9-2.8-2.82.7
Bone: minimum diameter0.10.20.8-0.00.1-0.3-0.20.30.40.30.30.5-0.50.60.50.5-0.9
Time in familiar zone, hab. session 12.12.32.81.4-1.41.51.5-1.4-1.7-1.7-1.5-1.61.6-1.6-1.6-1.71.0
Time in novel zone, hab. session 11.51.72.6-0.91.0-1.2-1.11.11.31.31.21.4-1.41.51.51.5-1.6
Total zone transitions, hab. session 10.30.51.31.2-1.10.70.9-0.7-0.6-0.8-0.7-0.30.10.10.70.50.4
Total locomotion distance, hab. session 10.40.61.81.3-1.20.70.9-0.6-0.5-0.8-0.7-0.1-0.20.41.00.8-0.2
Locomotion velocity, hab. session 10.60.92.51.6-1.51.01.2-1.0-0.8-1.2-1.0-0.50.2-0.00.70.50.6
Time in familiar zone, hab. session 26.77.68.62.5-2.62.82.7-2.8-2.9-2.8-2.8-2.92.9-2.9-2.8-2.92.3
Time in novel zone, hab. session 25.45.96.6-2.12.2-2.4-2.42.42.62.42.42.5-2.62.62.42.5-2.4
Total zone transitions, hab. session 21.31.75.8-0.30.3-0.9-0.70.91.20.80.91.4-1.61.72.42.3-0.5
Total locomotion distance, hab. session 20.40.61.41.2-1.20.70.9-0.7-0.5-0.9-0.7-0.30.10.00.70.50.9
Locomotion velocity, hab. session 20.40.61.41.2-1.20.60.9-0.6-0.4-0.8-0.6-0.2-0.10.31.10.90.8
Novel to familiar place preference ratio4.45.86.9-2.02.1-2.4-2.32.32.42.52.42.5-2.62.62.62.6-2.4
Novelty place preference2.93.74.8-1.51.6-1.9-1.81.81.81.91.92.0-2.12.12.12.2-2.0
Time in novel zone, NPP test3.34.04.8-1.61.8-2.0-1.91.92.02.12.02.1-2.22.22.12.2-2.1
Total zone transitions, NPP test0.40.62.6-0.0-0.0-0.4-0.20.40.60.20.40.7-0.80.91.61.50.5
Total locomotion distance, NPP test0.40.62.5-0.00.0-0.5-0.30.50.70.30.50.8-0.91.01.61.4-0.1
Locomotion velocity, NPP test0.30.41.80.3-0.3-0.20.00.20.40.00.20.5-0.70.81.31.20.2
Intraocular pressure0.40.72.1-0.20.00.40.2-0.4-0.5-0.4-0.4-0.81.0-1.1-1.5-1.31.4
Delta distance traveled before/after self-admin0.40.50.80.5-0.60.60.6-0.6-0.5-0.7-0.9-0.70.7-0.7-0.8-0.90.7
Delta ambulatory time before/after self-admin0.20.30.70.5-0.60.50.6-0.5-0.4-0.6-0.8-0.50.5-0.5-0.4-0.60.5
Parametrial fat weight0.00.00.20.0-0.0-0.1-0.00.00.20.20.10.2-0.30.30.40.40.1
Pavlov. Cond. lever latency0.30.41.4-0.00.00.30.2-0.3-0.5-0.2-0.3-0.60.8-0.9-1.2-1.10.4
Pavlov. Cond. magazine entry latency2.63.44.11.9-2.02.02.0-1.9-1.7-2.0-2.0-1.81.8-1.7-1.3-1.51.9
Pavlov. Cond. change in total contacts0.00.00.10.2-0.20.20.2-0.2-0.0-0.2-0.2-0.10.1-0.10.10.00.4
Pavlov. Cond. index score0.20.20.50.7-0.70.50.6-0.5-0.3-0.6-0.5-0.30.2-0.10.10.00.5
Pavlov. Cond. latency score0.10.20.50.6-0.70.40.5-0.4-0.2-0.5-0.4-0.1-0.00.10.40.30.3
Pavlov. Cond. lever contacts0.30.31.2-0.00.0-0.3-0.20.30.50.20.30.6-0.70.81.11.0-0.4
Pavlov. Cond. magazine entry number0.70.91.2-0.91.0-1.0-1.00.90.81.01.00.9-0.90.90.70.8-1.1
Pavlov. Cond. intertrial magazine entries0.40.51.00.3-0.40.60.5-0.6-0.5-0.6-0.6-0.80.8-0.9-1.0-1.00.9
Pavlov. Cond. lever-magazine prob. diff.0.30.30.70.8-0.80.60.7-0.6-0.5-0.7-0.6-0.50.4-0.3-0.0-0.10.6
Pavlov. Cond. response bias0.70.81.20.9-1.01.01.0-0.9-0.8-1.0-1.0-0.90.8-0.8-0.6-0.71.1
Pavlov. Cond. lever latency0.81.11.7-1.11.0-1.1-1.11.11.11.11.11.0-1.00.91.31.20.2
Pavlov. Cond. magazine entry latency0.30.40.60.8-0.70.70.7-0.7-0.7-0.7-0.7-0.60.6-0.6-0.7-0.7-0.2
Pavlov. Cond. change in total contacts0.41.11.61.0-0.91.01.0-1.1-1.1-1.0-1.0-1.11.1-1.1-1.3-1.20.4
Pavlov. Cond. index score0.61.01.51.0-0.91.01.0-1.0-1.1-1.0-1.0-1.01.0-0.9-1.2-1.2-0.1
Pavlov. Cond. latency score0.50.91.21.1-0.91.01.0-1.0-1.0-1.0-1.0-0.90.9-0.8-1.0-1.0-0.2
Pavlov. Cond. lever contacts0.71.02.00.9-0.81.00.9-1.0-1.0-1.0-1.0-1.01.0-1.0-1.4-1.3-0.2
Pavlov. Cond. magazine entry number0.60.71.1-1.00.9-0.9-0.90.91.00.90.90.8-0.80.70.80.90.3
Pavlov. Cond. intertrial magazine entries0.10.20.5-0.70.6-0.5-0.60.50.40.50.50.3-0.20.1-0.4-0.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.60.91.21.1-0.91.01.0-1.0-1.0-1.0-1.0-0.90.9-0.8-1.1-1.1-0.2
Pavlov. Cond. response bias1.92.63.91.6-1.51.61.6-1.6-1.7-1.6-1.6-1.61.6-1.6-2.0-1.90.3
Time in closed arm before self-admin0.61.01.7-0.70.7-0.9-0.81.01.10.90.91.1-1.21.31.31.2-0.9
Time in closed arm after self-admin0.40.41.40.3-0.30.50.4-0.4-0.4-0.5-0.5-0.60.7-0.7-1.2-1.10.7
Time in open arm before self-admin0.20.20.40.6-0.50.50.5-0.6-0.6-0.3-0.6-0.40.4-0.3-0.1-0.10.1
Time in open arm after self-admin0.80.91.2-1.01.0-1.1-1.00.90.91.11.00.9-0.90.81.11.1-0.8
Bone: periosteal estimation0.51.12.3-0.50.7-0.9-0.80.91.10.90.91.2-1.21.31.21.2-1.5
Bone: periosteal perimeter0.10.10.70.5-0.30.10.2-0.10.1-0.1-0.10.2-0.30.40.50.4-0.8
Bone: post-yield work0.40.81.1-1.01.0-1.0-1.00.91.00.91.00.9-0.80.80.50.6-0.8
Progressive ratio test 1 active lever presses0.20.30.70.1-0.20.50.3-0.4-0.5-0.4-0.4-0.70.8-0.9-0.8-0.80.4
Progressive ratio test 1 breakpoint0.20.30.70.0-0.10.50.3-0.4-0.5-0.4-0.3-0.60.8-0.8-0.8-0.80.3
Progressive ratio test 1 inactive lever presses0.20.50.70.5-0.50.70.6-0.6-0.7-0.6-0.6-0.80.8-0.8-0.8-0.80.6
Progressive ratio test 2 active lever presses0.60.91.70.5-0.50.90.7-1.0-1.1-0.6-0.7-1.11.2-1.3-1.1-1.10.7
Progressive ratio test 2 breakpoint0.81.01.80.5-0.61.00.8-1.0-1.1-0.7-0.8-1.21.3-1.4-1.2-1.10.8
Progressive ratio test 2 inactive lever presses0.10.20.40.4-0.40.60.5-0.6-0.6-0.3-0.4-0.50.5-0.5-0.1-0.20.4
Incentive Sensitization - Responses0.10.20.7-0.10.00.40.1-0.4-0.5-0.0-0.2-0.60.7-0.8-0.5-0.50.8
Incentive Sensitization - Breakpoint0.10.30.70.1-0.10.50.2-0.5-0.6-0.1-0.3-0.60.7-0.8-0.5-0.50.8
Sum of active levers in priming session hrs 5-60.00.00.4-0.00.10.0-0.10.0-0.20.10.00.0-0.00.0-0.6-0.2-0.1
Progressive ratio0.10.31.5-0.80.6-0.5-0.60.40.40.40.50.3-0.20.10.60.51.2
Food seeking constrained by brief footshock0.20.21.50.3-0.40.30.4-0.3-0.3-0.3-0.3-0.30.2-0.20.20.11.2
Seeking ratio, punishment vs. effort0.10.20.50.7-0.60.40.5-0.4-0.3-0.4-0.4-0.20.2-0.1-0.3-0.3-0.1
Retroperitoneal fat weight0.20.92.3-1.51.4-1.2-1.31.11.21.11.20.7-0.60.40.10.30.3
Reaction time number correct0.10.30.9-1.00.9-0.4-0.60.50.30.40.40.10.1-0.3-0.7-0.6-0.3
Reaction time mean minus median0.10.81.21.0-0.91.00.9-1.1-1.1-0.9-0.9-0.90.9-0.9-0.9-0.90.1
Reaction time mean minus median AUC0.00.31.40.10.0-0.2-0.10.10.20.20.30.5-0.50.70.80.7-1.2
Reaction time num false alarms0.10.10.7-0.40.4-0.2-0.30.00.00.20.2-0.10.2-0.3-0.5-0.4-0.8
Reaction time num false alarms AUC0.10.10.4-0.40.5-0.2-0.3-0.0-0.00.20.2-0.20.3-0.4-0.6-0.5-0.7
Reaction time trials correct on left0.10.30.9-1.00.9-0.4-0.60.50.30.40.40.10.1-0.3-0.7-0.6-0.3
Reaction time trials on left0.10.30.9-1.00.9-0.4-0.60.50.30.50.50.10.1-0.2-0.6-0.5-0.4
Reaction time mean0.10.20.8-0.00.2-0.3-0.20.20.30.30.30.4-0.50.60.70.5-0.9
Reaction time mean AUC0.10.20.9-0.10.2-0.4-0.30.30.40.30.30.5-0.50.60.70.6-1.0
Median of all reaction times0.50.71.2-0.50.6-0.8-0.70.70.80.80.70.9-1.01.01.11.0-1.1
Reaction time omissions0.00.10.30.6-0.50.30.3-0.4-0.2-0.2-0.2-0.1-0.00.10.20.30.0
Reaction time false alarm rate0.00.10.6-0.10.2-0.2-0.20.00.10.20.20.1-0.10.10.10.1-0.8
Reaction time premature initiation rate1.11.72.01.1-1.21.31.3-1.4-1.3-1.3-1.3-1.41.4-1.4-1.3-1.41.1
Reaction time premature initiations0.61.83.30.7-0.81.31.0-1.2-1.2-1.2-1.2-1.51.6-1.7-1.8-1.81.0
Std. dev. reaction times0.00.10.30.6-0.40.40.4-0.5-0.5-0.4-0.4-0.30.3-0.2-0.1-0.2-0.3
Reaction time trials completed0.10.30.9-1.00.9-0.4-0.60.50.30.50.50.10.1-0.2-0.6-0.5-0.4
Reaction time trials AUC0.10.30.9-0.90.8-0.3-0.60.40.20.40.4-0.00.2-0.4-0.8-0.7-0.2
Run reversals in cocaine runway, females0.20.30.60.7-0.80.60.7-0.7-0.6-0.6-0.5-0.40.3-0.2-0.2-0.1-0.0
Run reversals in cocaine runway, males0.91.01.71.2-1.31.11.2-1.1-0.9-1.2-1.1-0.90.8-0.7-0.9-0.90.5
Latency to leave start box in cocaine runway0.20.30.90.9-0.80.60.7-0.6-0.5-0.4-0.4-0.20.10.10.20.3-0.3
Latency to leave start box in cocaine runway, F0.50.61.80.1-0.1-0.2-0.20.20.50.50.50.7-0.91.11.21.3-1.2
Latency to leave start box in cocaine runway, M2.32.22.51.4-1.41.51.4-1.5-1.6-1.5-1.5-1.51.5-1.5-1.5-1.51.3
Std. dev. time between licks in bursts0.30.61.21.1-1.00.80.9-0.8-0.8-0.8-0.8-0.60.5-0.4-0.2-0.3-0.5
Total sessions with >9 infusions0.50.61.10.5-0.50.90.7-0.8-0.8-0.5-0.6-0.80.9-0.9-1.0-0.90.3
Short access day 1 total inactive lever presses0.20.51.20.6-0.60.80.7-0.7-0.7-0.6-0.7-0.70.7-0.8-0.3-0.41.1
Short access day 10 total inactive lever presses0.00.20.50.1-0.10.30.2-0.4-0.4-0.2-0.2-0.50.6-0.6-0.7-0.60.7
Short access day 1 total infusions0.20.30.60.6-0.60.70.6-0.6-0.6-0.5-0.6-0.60.6-0.6-0.4-0.50.5
Short access day 10 total infusions0.10.20.50.1-0.20.50.3-0.4-0.5-0.3-0.2-0.60.6-0.7-0.7-0.60.3
Short access total infusions0.40.50.80.6-0.60.90.7-0.8-0.8-0.6-0.6-0.80.8-0.9-0.7-0.70.5
Short access day 1 locomotion1.11.92.31.4-1.31.51.4-1.4-1.5-1.2-1.4-1.41.4-1.4-1.5-1.40.7
Short access day 10 total locomotion2.49.711.32.9-2.93.33.0-3.2-3.3-2.9-3.0-3.33.4-3.3-3.1-3.12.8
Short access total locomotion2.33.54.51.8-1.72.11.9-2.0-2.0-1.7-1.8-2.02.0-2.0-2.1-2.01.3
One hour access (0.3 mA shock)0.00.00.0-0.10.10.1-0.0-0.0-0.10.10.1-0.10.1-0.20.10.1-0.1
Compulsive drug intake1.32.03.1-0.91.0-1.3-1.21.31.41.41.41.6-1.61.71.61.7-1.4
One hour access (shock baseline)0.30.91.50.6-0.71.00.8-0.9-1.0-0.9-0.9-1.11.2-1.2-1.0-1.10.6
Social response proportion0.40.61.41.1-1.00.70.9-0.6-0.6-0.9-0.8-0.60.5-0.40.20.01.2
Social responses5.26.911.23.4-3.12.93.0-2.8-2.8-2.9-2.9-2.52.3-2.1-1.7-1.81.7
Social time0.30.50.7-0.80.7-0.8-0.80.80.70.70.70.7-0.60.60.50.60.3
Soleus weight7.522.027.3-5.25.2-5.0-5.15.15.05.15.04.7-4.54.33.43.6-3.9
Bone: stiffness2.74.95.8-2.02.2-2.3-2.22.22.42.32.32.3-2.22.21.92.0-2.2
Tibialis anterior weight0.93.03.9-2.02.0-2.0-1.91.71.71.92.01.7-1.71.60.91.3-1.6
Time to tail flick, vehicle, before self-admin0.10.10.40.3-0.30.20.2-0.2-0.2-0.2-0.1-0.1-0.00.1-0.6-0.2-0.2
Time to tail flick, vehicle, after self-admin0.51.02.00.4-0.50.70.6-0.7-0.8-0.9-0.6-1.11.2-1.3-1.4-1.41.3
Time to tail flick, test, before self-admin0.10.10.30.6-0.50.40.4-0.3-0.2-0.3-0.5-0.10.00.00.30.0-0.3
Time to tail flick, test, after self-admin0.10.10.10.2-0.20.20.2-0.2-0.0-0.3-0.2-0.20.2-0.2-0.3-0.40.2
Delta time to tail flick, vehicle, before/after SA0.10.20.4-0.60.5-0.2-0.30.20.10.00.3-0.20.4-0.5-0.4-0.50.7
Delta time to tail flick, test, before/after SA0.20.20.8-0.10.10.10.1-0.2-0.2-0.3-0.2-0.40.5-0.6-0.9-0.80.7
Tibia length0.82.32.81.6-1.61.61.6-1.6-1.6-1.7-1.6-1.61.6-1.5-1.2-1.31.2
Ambulatory time before self-admin0.10.20.5-0.20.3-0.3-0.30.20.20.50.60.4-0.40.40.20.5-0.7
Ambulatory time after self-admin0.00.00.00.1-0.1-0.00.0-0.1-0.00.1-0.00.0-0.10.1-0.10.1-0.2
Bone: tissue strength1.92.02.4-1.41.4-1.5-1.51.51.61.51.51.5-1.51.41.41.5-0.8
Total heroin consumption1.31.52.21.5-1.41.31.3-1.3-1.5-1.3-1.2-1.11.0-1.0-1.2-1.00.8
Bone: trabecular number0.10.20.70.8-0.70.40.6-0.4-0.4-0.5-0.4-0.1-0.10.20.40.3-0.4
Bone: trabecular spacing0.30.41.5-0.80.7-0.1-0.40.1-0.00.10.1-0.40.6-0.8-1.2-1.10.7
Bone: trabecular thickness1.31.85.50.20.1-0.7-0.40.70.90.70.71.4-1.71.92.42.2-1.8
Bone: trabecular tissue density0.81.32.3-1.51.4-1.3-1.41.31.41.31.31.1-1.00.80.80.9-0.1
Water consumed over 24 hours0.61.11.8-0.91.0-1.1-1.01.11.11.11.11.1-1.21.20.70.9-1.3
Number of responses in last shaping day1.82.33.21.3-1.31.71.5-1.5-1.6-1.4-1.4-1.61.6-1.6-1.8-1.70.9