Hub : Genes

Sf3a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Sf3a1 0.05 0.03 4.6e-07 0.06 0.06 0.06 0.06 1.3e-07 1.2e-07 4.4e-07 2.8e-07
2 Liver gene expression Sf3a1 0.04 0.03 5.6e-04 0.02 0.02 0.01 0.02 2.3e-03 3.5e-03 1.6e-02 1.7e-03
3 Liver mRNA stability Sf3a1 0.06 0.04 1.2e-05 0.05 0.04 0.04 0.05 3.5e-06 1.8e-05 7.0e-05 3.8e-06
4 Brain gene expression Sf3a1 0.4 0.11 0.0e+00 0.3 0.28 0.28 0.3 7.3e-28 1.1e-26 1.1e-25 4.8e-28
5 IC gene expression Sf3a1 0.65 0.12 5.6e-17 0.4 0.38 0.4 0.4 4.5e-18 4.7e-17 4.5e-18 3.4e-18
6 NAcc gene expression Sf3a1 0.36 0.09 0.0e+00 0.33 0.32 0.33 0.34 1.2e-51 1.1e-49 7.6e-52 2.4e-52
7 PL gene expression Sf3a1 0.51 0.11 0.0e+00 0.46 0.44 0.45 0.46 2.7e-56 1.6e-52 2.5e-54 2.6e-56
8 BLA gene expression Sf3a1 0.35 0.12 5.0e-16 0.26 0.25 0.25 0.25 6.3e-14 1.3e-13 1.0e-13 2.5e-13
9 pVTA gene expression Sf3a1 0.21 0.07 0.0e+00 0.25 0.26 0.27 0.27 4.2e-20 8.8e-21 1.6e-21 7.9e-22
10 LHb gene expression Sf3a1 0.33 0.17 9.7e-04 0.16 0.09 0.09 0.14 1.3e-04 4.7e-03 3.2e-03 4.5e-04
11 IL gene expression Sf3a1 0.41 0.14 2.9e-06 0.21 0.14 0.14 0.21 1.0e-05 3.9e-04 3.8e-04 1.1e-05
12 OFC gene expression Sf3a1 0.56 0.14 6.9e-09 0.23 0.21 0.15 0.2 4.4e-06 1.0e-05 1.9e-04 1.6e-05
13 Adipose mRNA stability Sf3a1 0.1 0.05 4.0e-09 0.06 0.06 0.06 0.06 2.4e-07 3.5e-07 1.0e-07 9.3e-08
14 LHb mRNA stability Sf3a1 0.5 0.25 9.8e-03 0.07 0.07 0.05 0.08 8.5e-03 1.1e-02 2.4e-02 6.7e-03
15 RMTg gene expression Sf3a1 0.34 0.14 1.6e-04 0.07 0.07 0.04 0.06 6.9e-03 6.6e-03 2.9e-02 1.2e-02
16 Brain mRNA stability Sf3a1 0.04 0.03 1.7e-03 0.03 0.03 0.03 0.03 1.9e-03 4.9e-04 5.2e-04 9.0e-04
17 BLA mRNA stability Sf3a1 0.09 0.06 2.6e-03 0.03 0.02 0.03 0.03 1.3e-02 4.2e-02 1.6e-02 1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.71.22.91.20.91.01.10.90.91.11.11.21.21.21.20.70.61.70.51.3
Area under the delay curve7.79.011.0-3.3-3.2-3.3-3.3-3.2-3.2-3.2-3.1-3.2-2.9-3.0-3.0-2.5-2.8-3.3-2.80.3
BMI with tail0.51.86.7-1.9-1.2-1.6-1.4-1.4-1.4-1.3-1.2-1.3-1.2-1.0-1.0-0.8-1.1-2.6-0.9-0.6
BMI without tail0.30.93.1-1.5-1.2-1.1-0.9-0.9-0.8-0.7-0.5-0.8-0.5-0.6-0.6-0.4-0.5-1.80.3-1.4
Body weight2.29.719.4-4.4-3.4-3.4-3.1-3.4-3.3-3.2-3.1-3.0-2.7-2.7-2.7-2.7-3.2-3.9-1.5-2.2
Weight adjusted by age0.81.22.9-1.7-1.3-1.0-0.9-1.0-1.1-1.1-1.0-0.7-1.0-0.7-0.7-0.9-1.3-1.6-0.3-1.4
Bone surface0.10.10.3-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.3-0.2-0.2-0.3-0.3-0.5-0.6-0.2-0.30.6
Bone volume0.00.10.50.1-0.0-0.00.1-0.00.00.20.10.20.20.10.1-0.3-0.40.5-0.10.7
Breakpoint value in progressive ratio session0.10.20.3-0.4-0.4-0.5-0.5-0.4-0.3-0.2-0.2-0.5-0.3-0.4-0.4-0.4-0.5-0.1-0.50.2
Number of licking bursts1.01.62.9-1.6-1.7-1.4-1.5-1.2-1.2-1.3-1.0-1.5-1.3-1.4-1.4-1.3-1.0-0.3-0.3-1.2
Context. condit. distance diff. score3.03.65.31.92.31.92.11.81.81.82.12.02.22.22.22.21.91.41.40.7
Locomotion velocity, session 10.10.20.80.90.70.30.10.30.30.20.10.30.30.30.3-0.1-0.0-0.2-0.70.5
Locomotion distance, session 12.43.04.31.81.82.11.82.12.01.81.62.11.92.02.01.41.21.21.20.8
Locomotion velocity, session 20.40.42.31.50.70.20.00.10.10.50.30.20.30.20.2-0.30.01.0-1.11.3
Locomotion distance, session 22.13.06.22.52.01.71.41.81.82.01.71.91.81.71.71.41.51.20.41.9
Locomotion velocity, session 31.51.72.71.31.61.51.51.51.61.61.01.51.31.21.21.51.20.70.80.8
Locomotion distance, session 30.50.51.6-0.4-0.3-0.7-0.6-0.6-0.5-0.5-0.9-0.5-0.8-1.0-1.0-0.6-0.6-1.3-0.90.2
Stereotopy head waving bouts, day 31.72.02.71.61.61.61.51.61.61.51.41.51.51.61.60.90.91.51.20.0
Stereotopy head waving duration, day 33.34.05.42.12.32.22.12.22.22.12.02.12.22.32.31.61.61.61.60.1
Locomotion velocity, session 70.10.10.40.10.2-0.00.0-0.1-0.1-0.1-0.3-0.1-0.1-0.3-0.3-0.6-0.6-0.4-0.4-0.1
Locomotion distance, session 70.60.71.91.21.31.00.90.90.90.90.60.90.80.50.50.70.60.4-0.01.4
Stereotopy head waving bouts, day 70.20.30.8-0.7-0.7-0.5-0.6-0.6-0.6-0.4-0.5-0.3-0.5-0.2-0.2-0.4-0.6-0.9-0.40.1
Stereotopy head waving duration, day 70.10.10.6-0.7-0.6-0.3-0.4-0.3-0.3-0.3-0.4-0.2-0.3-0.0-0.0-0.2-0.4-0.80.0-0.2
Locomotion velocity, session 81.21.44.02.01.61.21.11.11.01.11.31.11.20.90.91.01.41.50.30.8
Locomotion distance, session 88.412.216.63.94.13.73.63.63.53.63.83.63.93.73.73.53.42.92.51.3
Degree of sensitization distance5.05.27.02.52.52.42.42.22.12.12.62.22.62.62.62.02.12.61.70.7
Degree of sensitization stereotypy0.50.61.2-1.1-1.1-0.9-0.9-0.8-0.9-0.7-0.7-0.6-0.8-0.6-0.6-0.5-0.7-1.0-0.4-0.2
Conditioned locomotion0.80.92.00.70.81.10.91.01.10.90.91.01.01.11.11.00.70.50.71.4
Cocaine response after cond. corrected0.80.91.4-0.9-1.1-1.0-1.0-1.0-0.9-0.8-1.1-0.8-1.0-1.0-1.0-1.1-1.2-0.6-1.10.6
Cocaine response after cond. not corrected1.31.62.7-1.6-1.4-1.2-1.2-1.2-1.1-1.0-1.6-1.1-1.3-1.3-1.3-1.5-1.6-0.7-1.10.0
Cocaine response before conditioning0.10.11.2-0.50.10.10.10.10.10.4-0.30.2-0.0-0.0-0.0-0.1-0.1-0.00.5-1.1
Saline control response0.91.22.31.41.51.31.41.21.11.11.01.31.21.31.30.90.80.10.40.2
Bone: connectivity density0.71.01.41.01.01.11.11.01.01.20.81.01.11.21.20.80.61.10.51.2
Bone: cortical apparent density0.10.20.4-0.6-0.6-0.4-0.5-0.5-0.6-0.6-0.2-0.5-0.4-0.4-0.4-0.00.1-0.4-0.10.2
Bone: cortical area2.03.07.4-2.7-1.8-1.4-1.4-1.6-1.6-1.6-1.7-1.5-1.5-1.5-1.5-1.7-1.9-2.1-0.1-2.6
Bone: cortical porosity0.30.31.1-0.3-0.6-0.3-0.5-0.10.00.0-0.8-0.4-0.8-1.1-1.1-0.6-0.6-0.0-0.40.3
Bone: cortical porosity0.10.10.4-0.2-0.30.0-0.10.20.40.4-0.4-0.1-0.4-0.7-0.7-0.0-0.10.10.10.1
Bone: cortical thickness1.32.26.3-2.5-1.6-1.0-1.1-1.3-1.3-1.3-1.5-1.3-1.3-1.4-1.4-1.3-1.5-1.80.2-2.2
Bone: cortical thickness0.70.81.40.30.81.01.20.90.81.00.91.11.01.11.11.00.70.21.20.5
Bone: cortical tissue density0.20.30.6-0.6-0.7-0.5-0.6-0.6-0.7-0.8-0.3-0.6-0.5-0.5-0.5-0.1-0.0-0.5-0.20.2
Condit. Reinf. active minus inactive responses0.20.20.70.30.30.0-0.0-0.1-0.2-0.1-0.4-0.1-0.1-0.2-0.2-0.5-0.6-0.8-0.90.7
Condit. Reinf. active-inactive response ratio0.20.31.41.00.70.20.00.10.10.10.00.10.1-0.0-0.00.10.1-0.6-1.01.2
Condit. Reinf. active responses0.10.10.30.30.60.40.40.20.20.3-0.00.20.20.10.1-0.2-0.2-0.5-0.20.2
Condit. Reinf. inactive responses0.10.21.7-0.6-0.00.10.30.0-0.00.1-0.00.00.10.00.0-0.2-0.20.20.9-1.3
Incentive salience index mean0.40.61.9-0.5-0.3-0.5-0.5-0.7-0.7-0.7-0.9-0.6-0.6-0.6-0.6-0.9-1.1-1.4-1.00.1
Condit. Reinf. lever presses0.40.51.8-1.1-0.6-0.6-0.5-0.7-0.6-0.7-0.8-0.4-0.6-0.3-0.3-0.7-0.9-1.3-0.4-0.6
Condit. Reinf. active minus inactive responses1.11.52.01.01.41.31.41.11.01.11.21.41.41.41.41.21.10.71.3-1.1
Condit. Reinf. active-inactive response ratio0.10.10.30.20.30.20.20.10.00.20.20.30.30.30.30.30.1-0.4-0.20.5
Condit. Reinf. active responses2.23.14.51.92.11.92.11.81.61.61.82.02.02.02.01.71.61.11.4-0.3
Condit. Reinf. inactive responses2.33.04.42.02.12.02.11.91.81.61.71.81.81.81.81.51.61.41.4-0.3
Condit. Reinf. lever presses0.70.91.60.81.11.11.31.01.00.80.91.11.01.01.01.00.80.11.0-0.5
Condit. Reinf. lever reinforcers received1.92.64.11.72.01.92.01.71.51.41.61.81.81.81.81.61.40.71.2-0.2
Conditioned reinforcement - actives1.32.33.9-1.6-1.5-1.5-1.6-1.6-1.6-1.6-2.0-1.6-1.5-1.5-1.5-1.3-1.4-1.3-1.40.1
Conditioned reinforcement - inactives3.34.86.5-2.2-2.3-2.2-2.2-2.2-2.3-2.5-2.6-2.2-2.4-2.2-2.2-2.0-2.1-2.4-1.9-0.6
Conditioned locomotion1.72.23.1-1.7-1.6-1.4-1.5-1.5-1.6-1.6-1.7-1.6-1.8-1.6-1.6-1.6-1.4-0.8-1.0-0.6
Patch foraging indifference point 0 sec0.20.30.9-0.6-0.7-0.6-0.4-0.7-0.8-0.7-0.1-0.4-0.2-0.1-0.1-0.9-0.8-0.2-0.1-0.6
Patch foraging indifference point AUC0.20.31.01.00.80.30.50.50.60.70.40.50.50.50.5-0.4-0.4-0.1-0.20.2
Delay disc. indifference point, 0s delay5.15.67.5-2.7-2.5-2.4-2.5-2.4-2.4-2.3-2.6-2.5-2.7-2.4-2.4-1.5-1.9-2.7-2.31.8
Delay disc. indifference point, 16s delay5.66.28.2-2.3-2.5-2.9-2.8-2.8-2.8-2.9-2.4-2.7-2.3-2.5-2.5-2.3-2.3-2.2-2.70.7
Delay disc. indifference point, 2s delay4.85.38.0-2.8-2.6-2.4-2.5-2.4-2.3-2.3-2.7-2.4-2.5-2.3-2.3-1.7-2.1-2.6-1.90.4
Delay disc. indifference point, 24s delay4.04.56.2-2.1-2.1-2.2-2.3-2.2-2.2-2.2-2.5-2.2-2.1-2.2-2.2-1.6-1.9-2.1-2.51.6
Delay disc. indifference point, 4s delay3.94.15.7-2.3-2.2-2.1-2.1-2.0-2.0-2.0-2.4-2.0-2.1-2.0-2.0-1.9-2.1-2.3-1.7-0.1
Delay disc. indifference point, 8s delay2.02.34.1-1.6-1.5-1.7-1.7-1.6-1.6-1.8-1.3-1.6-1.3-1.5-1.5-1.4-1.5-2.0-1.2-0.6
Indifference point function ln k0.20.31.20.10.20.70.60.60.50.40.30.50.50.40.40.50.41.10.7-0.2
Indifference point function log k0.20.31.20.10.20.70.60.60.50.40.30.50.50.40.40.50.41.10.7-0.2
Patch foraging total patch changes 0 sec0.20.51.1-0.7-0.8-0.7-0.6-0.8-0.9-0.8-0.2-0.6-0.4-0.3-0.3-1.1-1.0-0.4-0.2-0.9
Patch foraging total patch changes 12 sec0.10.20.7-0.5-0.2-0.4-0.2-0.4-0.4-0.1-0.1-0.2-0.2-0.3-0.3-0.9-0.8-0.20.1-0.6
Patch foraging total patch changes 18 sec0.71.12.1-0.6-0.8-1.0-1.0-1.2-1.1-1.0-0.9-1.1-1.0-0.9-0.9-1.5-1.3-1.3-1.0-0.5
Patch foraging total patch changes 24 sec1.42.43.71.71.81.51.61.41.41.61.91.61.81.81.81.61.60.51.20.2
Patch foraging total patch changes 6 sec0.20.31.3-0.3-0.4-0.5-0.3-0.5-0.6-0.5-0.2-0.3-0.3-0.2-0.2-1.1-1.0-0.4-0.2-0.9
Patch foraging time to switch 0 sec0.10.21.4-0.6-0.4-0.1-0.2-0.3-0.3-0.50.2-0.3-0.2-0.2-0.21.01.2-0.00.70.2
Patch foraging water rate 0 sec0.51.06.5-0.8-0.4-0.7-0.5-0.5-0.5-0.2-0.8-0.5-0.6-0.5-0.5-1.6-1.6-0.9-0.3-2.5
Patch foraging water rate 12 sec0.30.53.50.20.50.70.50.81.01.10.00.60.40.40.4-0.1-0.2-0.20.8-1.9
Patch foraging water rate 18 sec1.82.86.70.61.31.82.01.71.51.51.51.71.61.51.51.41.21.52.6-2.3
Patch foraging water rate 24 sec0.60.910.40.00.60.70.60.60.60.80.20.50.30.10.10.10.30.11.3-3.2
Patch foraging water rate 6 sec0.60.910.0-0.20.30.40.50.60.81.00.10.50.30.20.2-0.3-0.2-0.01.4-3.2
Seeking ratio, delayed vs. immediate footshock0.10.10.70.9-0.00.4-0.10.10.20.00.50.0-0.3-0.3-0.3-0.2-0.10.8-0.50.2
Distance traveled before self-admin0.20.22.00.5-0.4-0.2-0.3-0.4-0.5-0.40.4-0.20.20.10.1-0.4-0.40.3-0.61.4
Distance traveled after self-admin0.20.32.1-0.0-0.6-0.4-0.4-0.5-0.6-0.6-0.1-0.5-0.3-0.5-0.5-0.3-0.5-0.1-0.61.4
Extensor digitorum longus weight2.28.615.3-3.9-3.3-2.9-2.7-3.0-3.0-2.9-3.0-2.5-2.8-2.5-2.5-3.6-3.7-2.8-1.3-2.7
Bone: elastic displacement0.30.41.50.00.30.70.80.50.3-0.00.60.40.50.30.30.80.80.71.2-1.0
Bone: elastic work0.50.66.3-0.9-0.20.30.50.1-0.1-0.20.20.20.20.00.00.20.20.41.6-2.5
Bone: endosteal estimation0.10.11.3-0.1-0.1-0.20.1-0.2-0.2-0.10.30.20.20.30.3-0.2-0.10.20.4-1.1
Bone: endosteal perimeter0.41.01.9-1.1-1.0-0.9-0.9-1.2-1.3-1.1-0.8-0.8-0.7-0.6-0.6-1.1-1.1-0.9-0.4-1.4
Epididymis fat weight0.72.56.1-2.5-2.1-1.9-1.8-1.9-1.8-1.7-1.4-1.6-1.0-1.3-1.3-1.2-1.4-1.5-0.7-0.6
Delta time in closed arm before/after self-admin5.95.58.02.22.52.42.42.52.42.52.52.52.22.52.52.82.32.21.61.7
Delta time in open arm before/after self-admin8.07.99.7-2.7-3.1-3.0-3.0-3.1-3.1-3.1-2.6-3.0-2.8-3.1-3.1-2.9-2.6-2.9-2.2-0.8
Diff in mean of infusions in LGA sessions0.30.33.40.3-0.2-0.4-0.3-0.1-0.00.00.3-0.2-0.0-0.3-0.30.60.4-0.4-0.81.8
Delay discount exponential model param7.58.410.53.23.13.23.23.13.03.13.03.02.82.82.82.52.83.22.6-0.2
Extinction: sum of active levers before priming1.31.43.8-0.7-1.0-1.3-1.2-1.2-1.2-1.1-1.1-1.2-1.2-1.1-1.1-0.8-0.9-1.0-1.91.7
Active lever presses in extinction session 60.80.82.5-0.7-0.9-0.9-0.9-0.7-0.7-0.8-1.2-0.9-1.1-1.0-1.0-0.4-0.5-0.3-1.11.6
Bone: final force0.30.53.4-1.1-0.6-0.5-0.3-0.6-0.6-0.5-0.2-0.5-0.4-0.5-0.5-0.5-0.4-0.90.6-1.8
Bone: final moment0.40.63.7-1.2-0.8-0.6-0.4-0.7-0.8-0.6-0.3-0.6-0.5-0.7-0.7-0.6-0.5-0.70.6-1.9
Food consumed during 24 hour testing period0.20.32.3-0.1-0.2-0.5-0.5-0.5-0.5-0.5-0.1-0.4-0.2-0.3-0.3-0.9-0.7-0.4-0.4-1.5
Glucose15.524.335.2-3.4-4.2-5.4-5.3-5.2-5.2-5.1-5.3-5.4-4.9-4.8-4.8-5.8-5.2-4.9-5.9-0.7
Heart weight0.40.61.1-0.9-0.4-0.8-0.8-0.8-0.8-0.8-0.9-0.6-1.0-0.7-0.7-0.7-0.7-0.8-0.8-0.5
Delay discount hyperbolic model param7.68.511.03.33.13.23.23.13.03.13.13.02.82.92.92.52.83.32.6-0.1
Intermittent access intake day 1-15 change0.81.62.7-0.9-1.0-1.4-1.3-1.4-1.5-1.5-1.3-1.3-1.4-1.2-1.2-1.2-1.1-1.1-1.60.6
Intermittent access intake escalation0.81.72.8-1.0-1.0-1.4-1.3-1.4-1.5-1.5-1.4-1.3-1.4-1.3-1.3-1.3-1.3-1.0-1.70.5
Intermittent access intake escalation 20.60.71.1-0.7-0.7-1.0-0.8-1.0-1.0-1.0-0.8-0.9-1.1-0.8-0.8-0.8-0.6-0.4-0.6-0.5
Intermitt. access day 1 inactive lever presses0.00.10.2-0.30.10.00.1-0.1-0.1-0.4-0.40.1-0.00.10.10.2-0.3-0.4-0.30.2
Intermitt. access day 15 inactive lever presses0.81.74.9-1.2-0.9-1.2-1.0-1.2-1.3-1.5-1.4-1.2-1.2-1.1-1.1-1.2-1.4-2.2-1.2-1.6
Intermitt. access escalation Index0.50.81.30.81.10.91.00.80.80.90.91.01.11.21.20.80.70.10.5-0.1
Intermittent access day 1 total infusions1.93.14.5-1.7-2.1-1.8-2.0-1.8-1.8-1.8-1.8-1.9-2.0-2.0-2.0-1.3-1.4-1.5-1.50.7
Intermittent access day 15 total infusions3.95.97.2-2.3-2.6-2.6-2.6-2.5-2.5-2.7-2.6-2.5-2.7-2.6-2.6-2.4-2.3-2.0-2.40.4
Intermittent access terminal intake (last 3 days)2.93.84.9-1.8-2.1-2.1-2.1-2.1-2.1-2.2-2.0-2.1-2.2-2.2-2.2-1.9-1.8-1.5-1.80.0
Intermittent access total infusions3.54.25.2-1.9-2.3-2.1-2.2-2.1-2.1-2.3-2.2-2.2-2.2-2.3-2.3-2.1-2.0-1.4-1.90.3
Intermittent access day 1 locomotion0.10.10.90.4-0.3-0.1-0.2-0.1-0.10.0-0.0-0.2-0.2-0.3-0.30.00.20.3-0.30.9
Intermittent access day 15 total locomotion2.74.86.6-2.5-2.3-2.3-2.3-2.3-2.3-2.4-2.2-2.4-2.6-2.4-2.4-1.8-1.9-2.1-1.6-0.6
Intermittent access total locomotion2.22.63.2-1.5-1.7-1.6-1.7-1.6-1.6-1.7-1.7-1.7-1.7-1.8-1.8-1.8-1.8-1.3-1.60.1
Intermittent access standard deviation0.10.10.2-0.3-0.2-0.3-0.1-0.4-0.4-0.4-0.5-0.4-0.5-0.4-0.4-0.2-0.1-0.5-0.1-0.3
Left kidney weight0.21.18.7-1.30.30.60.80.50.50.50.10.60.40.40.40.50.10.22.2-3.0
Right kidney weight0.20.84.5-1.4-0.20.30.60.40.40.40.40.60.60.60.60.90.40.32.1-1.8
Cocaine induced anxiety1.62.33.5-1.3-1.4-1.6-1.5-1.6-1.6-1.5-1.5-1.6-1.5-1.4-1.4-1.9-1.8-1.5-1.4-0.8
Post-drug Anxiety2.72.93.7-1.6-1.6-1.8-1.8-1.8-1.7-1.4-1.9-1.9-1.9-1.8-1.8-1.7-1.8-1.7-1.80.4
Baseline Anxiety0.30.43.8-0.3-0.3-0.4-0.5-0.4-0.3-0.2-0.7-0.5-0.4-0.5-0.5-0.0-0.0-0.3-0.72.0
Tail length0.93.56.2-2.4-2.3-1.8-1.6-1.7-1.7-1.7-1.8-1.6-1.5-1.9-1.9-2.3-2.3-1.1-0.2-2.5
Length with tail1.14.910.7-3.3-2.6-2.1-1.9-2.2-2.1-2.1-2.1-1.9-1.7-1.8-1.8-2.5-2.6-1.5-0.1-3.2
Length without tail0.61.94.9-2.2-1.4-1.4-1.3-1.5-1.5-1.6-1.5-1.3-1.3-1.0-1.0-1.4-1.5-0.9-0.5-1.3
Times rat made contact with spout0.10.21.00.80.1-0.3-0.5-0.5-0.30.00.0-0.2-0.2-0.3-0.3-0.30.0-0.1-1.00.0
Lifetime Intake3.13.74.9-1.7-2.2-2.0-2.1-2.0-2.0-2.2-2.1-2.0-2.0-2.1-2.1-2.1-2.0-1.2-1.80.2
Liver weight, left0.81.22.10.51.01.21.41.21.21.01.11.41.11.41.40.90.60.91.5-0.4
Liver weight, right1.01.84.00.51.21.41.61.41.41.31.31.51.31.51.51.21.10.72.0-1.1
Locomotor activity0.71.12.4-0.4-1.0-1.4-1.2-1.1-1.0-0.5-1.2-0.9-1.1-1.2-1.2-1.5-1.1-0.7-1.1-1.0
Locomotor testing distance0.61.11.8-1.2-1.1-1.0-0.9-1.0-0.9-0.6-1.2-0.8-1.1-1.4-1.4-1.2-1.1-0.8-0.2-1.0
Locomotor testing rearing1.42.94.4-1.7-1.7-1.7-1.6-1.7-1.6-1.7-2.0-1.7-1.9-2.1-2.1-1.7-1.6-1.4-1.3-1.0
Locomotion in novel chamber0.60.81.20.70.70.80.81.01.01.10.71.00.90.90.91.10.90.80.80.6
Locomotion in novel chamber post-restriction1.11.93.81.91.71.31.21.31.21.21.41.11.31.41.41.61.50.60.11.7
Fecal boli incidents, locomotor time 10.30.40.90.90.80.60.60.60.60.50.60.70.70.90.9-0.00.10.80.10.3
Change in fecal boli incidents, locomotor task0.10.10.60.80.40.20.20.20.20.30.30.20.00.00.00.30.20.1-0.20.2
Time >=10cm from walls, locomotor time 10.10.11.0-0.2-0.1-0.1-0.2-0.10.00.10.3-0.00.2-0.1-0.10.60.5-0.20.01.0
Bouts of movement, locomotor time 10.20.21.1-0.2-0.1-0.2-0.3-0.4-0.5-0.3-0.5-0.3-0.5-0.3-0.3-0.3-0.4-0.6-0.81.0
Total resting periods, locomotor time 10.30.31.1-0.2-0.2-0.3-0.3-0.4-0.5-0.4-0.6-0.4-0.6-0.4-0.4-0.2-0.4-1.0-1.01.0
Rest time, locomotor task time 10.00.00.10.40.30.20.30.10.10.2-0.20.2-0.10.20.2-0.1-0.1-0.3-0.1-0.3
Distance moved, locomotor task time 10.10.20.4-0.4-0.6-0.5-0.4-0.4-0.4-0.40.1-0.4-0.0-0.4-0.4-0.5-0.20.30.3-0.5
Vertical activity count, locomotor time 10.10.21.00.3-0.5-0.4-0.5-0.4-0.3-0.40.4-0.30.2-0.3-0.3-0.30.00.7-0.41.0
Time >=10cm from walls, locomotor time 20.10.20.50.60.60.50.50.40.30.40.40.10.4-0.0-0.00.50.50.40.10.7
Bouts of movement, locomotor time 20.10.20.5-0.10.70.50.50.50.50.50.20.50.10.30.30.50.0-0.40.3-0.0
Total resting periods, locomotor time 20.10.10.5-0.10.70.50.40.40.40.50.10.40.00.20.20.3-0.2-0.70.10.0
Rest time, locomotor task time 20.40.50.90.80.70.70.70.70.70.60.60.90.70.90.90.40.30.30.5-0.2
Distance moved, locomotor task time 20.00.00.2-0.10.00.10.0-0.1-0.2-0.20.1-0.20.1-0.2-0.20.20.40.40.3-0.0
Vertical activity count, locomotor time 20.20.21.50.0-0.3-0.2-0.3-0.3-0.4-0.4-0.2-0.5-0.2-0.6-0.6-0.2-0.10.4-0.61.2
Light reinforcement 10.10.32.4-1.0-0.2-0.20.1-0.1-0.2-0.2-0.40.0-0.1-0.1-0.1-0.4-0.6-0.70.6-1.6
Light reinforcement 20.20.33.2-0.6-0.2-0.10.30.10.00.10.40.30.30.30.3-0.10.0-0.11.3-1.8
Bone: marrow area0.00.10.9-0.1-0.1-0.20.1-0.2-0.2-0.10.30.20.30.30.3-0.2-0.10.20.3-0.9
Bone: maximum diameter3.05.79.0-3.0-2.3-2.2-2.3-2.4-2.4-2.4-2.4-2.2-2.2-2.0-2.0-2.7-2.7-2.6-1.2-3.0
Bone: maximum force0.20.44.3-0.9-0.4-0.20.0-0.4-0.4-0.30.1-0.1-0.0-0.1-0.1-0.2-0.1-0.51.0-2.1
Bone: maximum moment0.30.54.9-1.0-0.6-0.3-0.0-0.5-0.6-0.40.0-0.2-0.1-0.2-0.2-0.4-0.2-0.21.0-2.2
Mean time between licks in bursts0.10.10.90.90.60.00.20.20.10.20.3-0.00.30.20.2-0.20.00.5-0.5-0.3
Mean num. licks in bursts0.81.34.12.01.71.11.10.80.91.21.01.31.11.11.11.11.00.2-0.41.2
Cd content in liver0.70.71.2-0.6-0.8-1.1-0.9-1.1-1.1-0.8-0.7-0.9-0.6-0.7-0.7-1.1-1.0-0.7-0.9-0.3
Co content in liver0.40.41.0-0.8-0.7-0.6-0.6-0.6-0.6-0.5-0.8-0.5-0.4-0.5-0.5-0.8-1.0-0.8-0.5-0.1
Cu content in liver0.10.11.7-0.0-0.0-0.1-0.1-0.2-0.2-0.1-0.1-0.10.20.10.1-0.0-0.2-0.1-0.71.3
Fe content in liver1.51.85.61.81.41.31.21.41.31.11.01.21.31.21.21.61.30.7-0.22.4
K content in liver2.12.03.2-1.8-1.7-1.3-1.4-1.4-1.5-1.4-1.6-1.3-1.2-1.3-1.3-1.2-1.6-1.0-1.31.3
Mg content in liver2.32.34.5-2.1-1.7-1.6-1.6-1.6-1.5-1.4-1.9-1.5-1.5-1.6-1.6-1.3-1.5-1.4-1.20.0
Mn content in liver0.10.10.2-0.1-0.3-0.1-0.2-0.00.00.0-0.4-0.1-0.2-0.4-0.4-0.5-0.40.2-0.30.4
Na content in liver4.65.08.6-1.7-2.1-2.1-2.2-2.0-2.1-2.2-2.4-2.3-2.4-2.3-2.3-2.1-2.4-2.3-2.91.6
Rb content in liver0.70.91.4-1.1-1.2-1.1-1.0-1.2-1.1-1.1-0.7-0.9-0.5-0.7-0.7-1.1-1.0-0.9-0.60.0
Se content in liver1.61.83.2-1.8-1.8-1.5-1.5-1.4-1.4-1.5-1.6-1.4-1.1-1.3-1.3-1.1-1.4-0.8-1.20.1
Sr content in liver3.22.83.9-1.8-1.8-1.8-1.8-1.7-1.7-1.8-1.6-2.0-1.7-1.7-1.7-1.6-1.5-1.7-1.1-1.7
Zn content in liver0.20.22.0-0.5-0.1-0.10.10.00.00.1-0.10.00.1-0.1-0.1-0.4-0.40.20.6-1.4
Bone: minimum diameter0.30.52.30.00.40.70.60.50.50.70.50.70.60.90.90.40.30.41.1-1.5
Time in familiar zone, hab. session 10.50.51.11.00.60.70.60.60.50.31.10.50.70.50.50.81.10.70.70.2
Time in novel zone, hab. session 10.40.41.0-1.0-0.8-0.7-0.6-0.6-0.5-0.3-0.8-0.4-0.7-0.6-0.6-0.8-0.8-0.2-0.2-0.8
Total zone transitions, hab. session 10.20.31.41.20.80.80.60.70.70.60.60.60.50.20.20.20.30.20.10.4
Total locomotion distance, hab. session 10.10.10.60.60.20.30.00.20.20.4-0.10.1-0.0-0.2-0.2-0.2-0.20.0-0.50.8
Locomotion velocity, hab. session 10.10.20.60.80.60.50.30.50.50.60.00.30.20.00.0-0.0-0.1-0.1-0.40.8
Time in familiar zone, hab. session 23.13.25.72.01.92.01.72.01.91.51.91.41.71.51.52.32.41.81.41.2
Time in novel zone, hab. session 22.93.05.8-2.0-1.8-1.9-1.5-1.9-1.8-1.4-1.6-1.3-1.5-1.2-1.2-2.3-2.1-1.7-0.6-2.4
Total zone transitions, hab. session 20.10.10.70.0-0.0-0.1-0.2-0.1-0.10.1-0.20.1-0.00.10.1-0.8-0.8-0.8-0.2-0.5
Total locomotion distance, hab. session 20.40.51.3-0.5-0.6-0.7-0.8-0.7-0.6-0.4-0.7-0.5-0.6-0.5-0.5-1.1-1.0-1.0-0.6-0.9
Locomotion velocity, hab. session 20.60.81.8-0.7-0.8-0.9-1.0-0.9-0.8-0.6-0.9-0.7-0.8-0.7-0.7-1.4-1.3-1.2-0.9-0.6
Novel to familiar place preference ratio2.02.24.1-0.9-1.2-1.5-1.5-1.5-1.5-1.3-1.6-1.4-1.5-1.4-1.4-1.5-1.6-2.0-2.00.7
Novelty place preference1.82.03.4-1.0-1.2-1.5-1.4-1.4-1.4-1.3-1.6-1.4-1.4-1.4-1.4-1.5-1.6-1.8-1.80.4
Time in novel zone, NPP test1.51.62.9-0.9-1.0-1.3-1.2-1.3-1.3-1.2-1.4-1.3-1.3-1.3-1.3-1.4-1.4-1.7-1.60.1
Total zone transitions, NPP test0.40.61.10.50.81.10.80.90.90.80.61.00.91.01.00.50.30.40.70.4
Total locomotion distance, NPP test0.10.10.70.20.20.40.10.30.30.4-0.00.30.20.30.30.0-0.2-0.0-0.10.8
Locomotion velocity, NPP test0.10.11.6-0.0-0.10.1-0.2-0.0-0.00.1-0.30.0-0.10.00.0-0.3-0.4-0.2-0.61.3
Intraocular pressure0.20.31.7-0.1-0.2-0.5-0.5-0.5-0.6-0.2-0.5-0.5-0.4-0.4-0.4-0.6-0.3-1.3-0.4-0.7
Delta distance traveled before/after self-admin0.20.20.7-0.5-0.2-0.2-0.2-0.2-0.0-0.1-0.8-0.4-0.7-0.6-0.60.20.1-0.5-0.20.4
Delta ambulatory time before/after self-admin0.10.10.90.10.20.20.20.30.30.3-0.30.1-0.1-0.2-0.20.50.40.2-0.10.9
Parametrial fat weight2.66.012.5-1.2-1.9-2.9-2.7-2.7-2.6-2.4-2.3-2.4-2.3-2.2-2.2-2.5-2.2-3.5-3.30.6
Pavlov. Cond. lever latency0.20.20.6-0.1-0.4-0.5-0.5-0.4-0.5-0.5-0.4-0.5-0.4-0.6-0.6-0.4-0.30.2-0.80.4
Pavlov. Cond. magazine entry latency1.11.52.31.51.31.31.31.41.41.31.21.21.21.21.21.21.30.91.00.0
Pavlov. Cond. change in total contacts1.21.21.9-0.7-1.0-1.0-1.1-1.1-1.0-0.9-1.2-1.0-1.2-1.3-1.3-1.4-1.2-1.4-1.10.2
Pavlov. Cond. index score1.01.31.81.21.21.31.21.31.31.31.11.21.11.21.21.21.20.61.00.5
Pavlov. Cond. latency score0.91.21.61.11.11.21.21.21.31.21.01.11.01.11.11.11.10.61.10.2
Pavlov. Cond. lever contacts0.50.60.80.60.80.90.80.80.90.90.70.90.70.80.80.80.70.20.9-0.1
Pavlov. Cond. magazine entry number1.01.32.6-1.6-1.3-1.2-1.1-1.4-1.5-1.4-1.0-1.2-1.0-1.1-1.1-1.0-1.0-0.5-0.5-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.7-0.20.40.30.1-0.00.0-0.20.10.10.00.0-0.2-0.40.30.4-0.1
Pavlov. Cond. lever-magazine prob. diff.1.21.52.21.31.31.51.31.41.41.31.21.31.21.31.31.31.20.81.10.4
Pavlov. Cond. response bias0.30.40.70.70.70.80.60.80.80.80.40.70.50.60.60.40.40.30.30.5
Pavlov. Cond. lever latency1.52.13.9-2.0-2.0-1.5-1.5-1.4-1.5-1.3-1.6-1.4-1.5-1.5-1.5-1.5-1.6-0.6-0.8-0.2
Pavlov. Cond. magazine entry latency0.10.10.3-0.3-0.3-0.3-0.1-0.3-0.3-0.4-0.0-0.3-0.2-0.1-0.1-0.1-0.1-0.60.1-0.4
Pavlov. Cond. change in total contacts0.40.71.21.01.10.91.10.80.70.41.00.80.90.90.90.90.90.10.6-0.1
Pavlov. Cond. index score0.60.81.51.11.21.01.10.90.90.61.10.81.01.01.01.01.00.20.7-0.1
Pavlov. Cond. latency score0.81.11.71.21.31.11.21.11.00.81.21.01.11.11.11.11.10.30.9-0.2
Pavlov. Cond. lever contacts1.82.54.42.12.11.61.61.61.61.51.71.61.61.61.61.71.70.80.80.6
Pavlov. Cond. magazine entry number0.10.11.00.20.00.1-0.00.20.30.4-0.20.30.00.00.0-0.1-0.30.3-0.31.0
Pavlov. Cond. intertrial magazine entries0.10.20.40.40.50.50.30.60.60.50.10.60.40.40.40.20.00.7-0.10.6
Pavlov. Cond. lever-magazine prob. diff.0.70.91.51.11.21.01.11.00.90.71.10.91.01.01.01.11.10.30.8-0.1
Pavlov. Cond. response bias0.60.81.71.31.30.91.00.80.80.71.10.80.90.90.91.01.20.40.50.3
Time in closed arm before self-admin0.70.93.10.10.70.80.90.80.80.70.90.81.10.80.80.50.70.91.7-1.8
Time in closed arm after self-admin4.54.85.91.52.32.32.42.32.22.22.42.32.32.42.42.42.12.22.4-0.2
Time in open arm before self-admin0.00.00.10.20.20.20.20.30.40.4-0.10.2-0.30.10.10.10.00.20.00.1
Time in open arm after self-admin2.52.74.0-1.3-1.6-1.8-1.7-1.7-1.7-1.6-1.6-1.7-1.8-1.8-1.8-1.6-1.4-2.0-1.7-0.2
Bone: periosteal estimation0.51.04.9-1.5-1.0-0.8-0.6-0.9-1.0-0.8-0.6-0.6-0.6-0.4-0.4-1.0-1.0-0.90.3-2.2
Bone: periosteal perimeter1.42.55.3-2.3-1.7-1.4-1.4-1.6-1.6-1.5-1.6-1.2-1.4-1.2-1.2-1.6-1.8-2.0-0.6-2.0
Bone: post-yield work0.10.10.30.1-0.5-0.5-0.4-0.4-0.4-0.20.1-0.2-0.2-0.2-0.2-0.30.00.5-0.2-0.0
Progressive ratio test 1 active lever presses2.32.84.7-1.2-1.8-1.6-1.8-1.6-1.7-1.8-1.7-1.7-1.6-1.7-1.7-1.7-1.8-1.1-2.21.6
Progressive ratio test 1 breakpoint2.32.84.7-1.2-1.7-1.6-1.7-1.6-1.6-1.8-1.7-1.7-1.6-1.7-1.7-1.6-1.8-1.1-2.21.6
Progressive ratio test 1 inactive lever presses3.95.78.1-2.0-2.5-2.4-2.4-2.5-2.5-2.8-2.3-2.4-2.4-2.4-2.4-2.5-2.7-2.3-2.50.4
Progressive ratio test 2 active lever presses3.33.95.2-1.7-2.1-2.1-2.2-2.1-2.1-2.3-2.0-2.1-2.3-2.2-2.2-1.9-1.7-1.6-1.80.3
Progressive ratio test 2 breakpoint3.03.54.6-1.6-2.0-2.0-2.0-1.9-2.0-2.1-1.9-2.0-2.1-2.1-2.1-1.7-1.6-1.5-1.70.2
Progressive ratio test 2 inactive lever presses4.16.68.8-2.7-2.6-2.7-2.7-2.8-2.8-2.7-2.5-2.8-2.9-2.7-2.7-2.3-2.3-3.0-2.0-1.2
Incentive Sensitization - Responses1.82.53.6-1.6-1.7-1.8-1.8-1.8-1.8-1.8-1.5-1.8-1.9-1.7-1.7-1.2-0.9-1.5-1.0-0.7
Incentive Sensitization - Breakpoint1.72.33.2-1.6-1.6-1.7-1.7-1.7-1.7-1.7-1.4-1.7-1.8-1.7-1.7-1.1-0.8-1.5-0.8-0.9
Sum of active levers in priming session hrs 5-60.50.51.5-0.7-0.7-0.7-0.6-0.5-0.4-0.5-0.8-0.8-1.0-0.8-0.80.1-0.1-0.4-0.81.2
Progressive ratio0.30.51.2-0.6-1.0-0.7-0.8-0.9-1.0-1.1-0.6-0.9-0.8-0.8-0.8-0.5-0.1-0.2-0.2-0.2
Food seeking constrained by brief footshock3.54.26.4-2.2-2.5-2.1-2.1-2.1-2.1-2.2-2.2-2.1-2.5-2.3-2.3-2.1-2.0-1.6-1.1-0.3
Seeking ratio, punishment vs. effort0.10.20.9-0.50.10.00.30.20.30.4-0.40.2-0.3-0.0-0.0-0.5-0.9-0.50.1-0.6
Retroperitoneal fat weight0.52.39.2-1.2-1.1-1.8-1.7-1.5-1.6-1.4-1.4-1.4-1.0-1.1-1.1-1.4-1.4-3.0-1.7-0.0
Reaction time number correct0.20.54.00.70.60.50.50.40.50.50.50.30.50.40.4-0.00.30.60.8-2.0
Reaction time mean minus median0.10.31.0-0.2-0.4-1.0-0.7-0.9-0.8-0.6-0.3-0.6-0.4-0.4-0.4-0.10.0-0.0-0.90.6
Reaction time mean minus median AUC0.20.51.1-0.9-0.6-1.1-0.7-0.9-0.8-0.6-0.7-0.8-0.7-0.7-0.7-0.3-0.3-0.7-0.6-0.1
Reaction time num false alarms0.50.81.6-1.2-1.0-0.9-0.8-0.8-0.9-0.9-0.9-0.9-0.9-0.8-0.8-0.7-0.9-1.2-0.50.4
Reaction time num false alarms AUC0.30.51.6-1.3-0.9-0.7-0.6-0.7-0.7-0.7-0.6-0.8-0.7-0.7-0.7-0.4-0.6-1.00.0-0.0
Reaction time trials correct on left0.20.54.00.70.60.50.50.40.50.50.50.30.50.40.4-0.00.30.60.8-2.0
Reaction time trials on left0.30.53.80.70.60.60.60.50.50.50.50.30.50.50.50.00.40.60.8-2.0
Reaction time mean0.10.21.7-0.1-0.0-0.5-0.2-0.4-0.3-0.3-0.2-0.4-0.3-0.4-0.40.40.50.3-0.61.3
Reaction time mean AUC0.10.21.4-0.00.1-0.30.1-0.2-0.1-0.1-0.0-0.2-0.1-0.1-0.10.60.60.5-0.31.2
Median of all reaction times0.10.22.10.10.2-0.10.2-0.00.0-0.00.0-0.2-0.1-0.2-0.20.60.60.6-0.31.5
Reaction time omissions0.20.30.70.60.70.50.60.60.70.60.20.50.40.20.20.90.80.20.20.6
Reaction time false alarm rate0.60.92.5-1.6-1.1-0.9-0.9-0.8-0.9-0.9-0.9-0.9-1.0-0.9-0.9-0.4-0.7-1.2-0.30.8
Reaction time premature initiation rate4.86.68.42.32.82.92.92.92.92.92.62.92.72.72.72.62.21.72.50.1
Reaction time premature initiations3.05.36.82.22.62.62.62.52.52.62.32.52.42.32.32.11.91.62.3-0.9
Std. dev. reaction times0.30.51.2-0.5-0.5-1.1-0.8-1.1-1.0-0.7-0.5-0.9-0.7-0.7-0.7-0.10.1-0.4-0.90.6
Reaction time trials completed0.30.53.80.70.60.60.60.50.50.50.50.30.50.50.50.00.40.60.8-2.0
Reaction time trials AUC0.20.43.80.60.50.50.50.40.40.40.50.30.50.40.4-0.10.20.70.7-2.0
Run reversals in cocaine runway, females0.50.55.40.40.0-0.1-0.1-0.1-0.3-0.20.2-0.10.30.10.11.01.0-0.1-0.52.3
Run reversals in cocaine runway, males0.00.00.3-0.2-0.2-0.3-0.1-0.2-0.3-0.30.2-0.00.20.10.10.0-0.1-0.20.1-0.5
Latency to leave start box in cocaine runway0.10.10.6-0.0-0.3-0.0-0.1-0.2-0.3-0.4-0.3-0.00.00.20.20.2-0.1-0.5-0.40.8
Latency to leave start box in cocaine runway, F0.20.21.1-0.9-0.6-0.3-0.2-0.5-0.6-0.6-0.4-0.3-0.3-0.1-0.10.1-0.1-1.10.2-0.7
Latency to leave start box in cocaine runway, M0.30.32.80.80.10.10.00.10.1-0.0-0.20.10.20.20.2-0.2-0.30.1-1.11.7
Std. dev. time between licks in bursts0.70.91.91.41.21.11.11.00.90.91.00.71.01.01.00.60.71.00.50.3
Total sessions with >9 infusions0.10.10.30.40.20.40.30.30.30.20.30.40.50.40.40.40.10.10.20.3
Short access day 1 total inactive lever presses2.53.35.3-1.8-2.1-1.9-1.7-1.8-1.9-2.0-1.7-1.8-1.7-1.7-1.7-2.3-2.3-1.7-1.2-1.4
Short access day 10 total inactive lever presses0.20.43.3-0.10.50.40.70.40.40.10.30.60.50.70.70.2-0.1-0.10.7-1.8
Short access day 1 total infusions0.00.10.20.10.10.30.40.20.10.2-0.00.20.40.30.30.20.10.20.30.2
Short access day 10 total infusions0.10.10.80.2-0.4-0.2-0.3-0.1-0.1-0.2-0.1-0.2-0.1-0.3-0.3-0.1-0.10.0-0.40.9
Short access total infusions0.30.30.8-0.4-0.9-0.5-0.6-0.5-0.6-0.7-0.7-0.5-0.5-0.6-0.6-0.7-0.7-0.2-0.50.2
Short access day 1 locomotion0.70.91.70.80.70.81.00.70.60.71.30.91.31.21.20.80.71.01.2-0.4
Short access day 10 total locomotion1.42.65.32.31.41.71.51.71.71.61.81.71.81.61.61.41.41.90.91.0
Short access total locomotion2.53.04.62.11.71.91.91.81.81.82.01.92.01.91.91.41.31.71.50.1
One hour access (0.3 mA shock)2.63.05.0-1.3-1.8-1.9-1.9-1.9-2.0-2.2-1.6-1.9-1.9-1.7-1.7-1.7-1.5-1.1-1.90.8
Compulsive drug intake3.64.35.42.22.12.12.02.12.12.11.92.02.12.32.32.32.22.11.12.1
One hour access (shock baseline)4.97.49.3-2.4-2.9-2.9-2.9-2.9-2.9-3.0-2.8-2.9-3.0-3.0-3.0-2.8-2.7-2.0-2.60.0
Social response proportion0.30.41.10.0-0.3-0.6-0.5-0.6-0.6-0.5-0.3-0.8-0.5-0.7-0.7-1.1-0.6-0.2-0.6-0.8
Social responses0.50.61.3-0.3-0.6-0.9-0.8-0.7-0.6-0.5-0.6-0.9-0.8-0.9-0.9-1.1-0.8-0.5-0.7-1.1
Social time0.20.20.70.80.50.30.20.40.40.40.50.10.30.20.20.50.90.90.10.3
Soleus weight0.72.012.8-2.1-1.7-1.1-0.9-1.1-1.0-0.9-1.0-0.8-1.0-0.9-0.9-1.5-1.4-0.40.8-3.6
Bone: stiffness0.10.20.40.10.50.40.50.40.50.60.40.60.50.50.50.40.2-0.30.40.1
Tibialis anterior weight1.55.07.7-2.8-2.6-2.4-2.3-2.4-2.4-2.2-2.3-2.2-2.3-1.9-1.9-2.4-2.3-2.1-1.3-1.7
Time to tail flick, vehicle, before self-admin0.20.20.7-0.6-0.4-0.2-0.4-0.5-0.5-0.4-0.4-0.5-0.8-0.6-0.60.10.3-0.50.3-0.1
Time to tail flick, vehicle, after self-admin0.30.33.30.60.20.20.00.30.30.3-0.10.20.20.10.10.90.7-0.2-0.61.8
Time to tail flick, test, before self-admin0.80.81.80.61.00.80.91.31.41.20.61.00.90.80.80.50.40.70.9-0.9
Time to tail flick, test, after self-admin1.31.36.1-1.3-1.1-0.9-0.9-0.7-0.7-0.7-1.1-0.9-1.1-1.1-1.1-1.7-1.5-0.8-0.0-2.5
Delta time to tail flick, vehicle, before/after SA0.50.53.41.00.50.30.20.50.50.40.30.40.70.50.50.50.30.2-0.81.8
Delta time to tail flick, test, before/after SA1.21.21.9-1.1-1.1-1.1-1.1-1.3-1.4-1.3-0.9-1.2-1.2-1.1-1.1-1.3-1.1-0.9-0.8-0.9
Tibia length0.30.82.8-0.20.20.60.80.60.60.70.90.90.91.01.01.00.90.91.7-0.6
Ambulatory time before self-admin0.30.53.10.2-0.8-0.5-0.7-0.8-0.8-0.80.1-0.5-0.1-0.3-0.3-0.6-0.60.1-0.91.8
Ambulatory time after self-admin0.40.45.20.4-0.4-0.2-0.3-0.4-0.4-0.40.2-0.30.2-0.2-0.2-0.2-0.30.4-0.82.3
Bone: tissue strength0.50.54.40.10.20.50.50.30.30.20.60.20.30.00.00.40.80.91.2-2.1
Total heroin consumption0.40.41.00.50.60.60.70.70.70.61.00.60.70.60.60.50.50.90.7-0.2
Bone: trabecular number0.40.61.60.60.50.70.80.70.80.90.70.90.91.01.00.60.41.30.60.9
Bone: trabecular spacing1.41.83.0-1.2-1.4-1.4-1.4-1.4-1.4-1.7-1.0-1.6-1.3-1.3-1.3-1.2-1.0-1.7-0.7-1.6
Bone: trabecular thickness2.22.75.91.31.61.71.61.61.61.91.51.91.71.71.71.41.32.41.31.2
Bone: trabecular tissue density0.10.10.80.3-0.0-0.1-0.4-0.2-0.2-0.20.0-0.3-0.2-0.3-0.30.30.50.1-0.60.9
Water consumed over 24 hours0.10.20.80.90.1-0.2-0.1-0.2-0.2-0.00.70.00.20.10.1-0.40.20.7-0.1-0.9
Number of responses in last shaping day0.20.22.10.30.20.00.1-0.2-0.2-0.0-0.0-0.20.1-0.1-0.10.30.1-0.6-0.61.5