Hub : Genes

Septin3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Septin3 0.16 0.09 6.8e-03 0.07 0.06 0.04 0.06 1.1e-02 1.8e-02 3.9e-02 1.5e-02
2 Adipose gene expression Septin3 0.04 0.03 4.8e-05 0.01 0.02 0.01 0.01 4.1e-02 1.7e-03 4.3e-02 2.2e-02
3 pVTA gene expression Septin3 0.34 0.14 7.7e-13 0.22 0.25 0.28 0.28 9.2e-10 5.1e-11 9.7e-13 1.8e-12
4 Brain gene expression Septin3 0.58 0.09 0.0e+00 0.59 0.62 0.63 0.63 6.1e-68 8.2e-74 6.3e-75 6.2e-75
5 Brain mRNA stability Septin3 0.24 0.09 0.0e+00 0.2 0.2 0.2 0.21 7.4e-18 7.5e-18 7.9e-19 6.6e-19
6 BLA gene expression Septin3 0.28 0.11 3.8e-08 0.1 0.14 0.14 0.15 5.1e-06 4.1e-08 3.6e-08 2.2e-08
7 PL mRNA stability Septin3 0.05 0.03 1.3e-06 0.04 0.04 0.04 0.03 6.0e-05 1.0e-05 2.0e-05 2.2e-04
8 PL gene expression Septin3 0.22 0.08 0.0e+00 0.23 0.22 0.23 0.23 1.5e-24 1.6e-23 1.5e-24 7.5e-25
9 IL gene expression Septin3 0.26 0.13 2.9e-03 0.03 0.06 0.06 0.06 7.5e-02 1.3e-02 1.5e-02 1.4e-02
10 OFC gene expression Septin3 0.51 0.14 4.4e-07 0.1 0.28 0.27 0.27 2.3e-03 1.9e-07 3.8e-07 3.3e-07
11 BLA mRNA stability Septin3 0.22 0.1 5.5e-07 0.14 0.11 0.13 0.13 4.8e-08 1.2e-06 1.8e-07 1.4e-07
12 OFC mRNA stability Septin3 0.18 0.1 3.5e-03 0.06 0.06 0.05 0.04 1.3e-02 1.3e-02 2.5e-02 3.5e-02
13 NAcc gene expression Septin3 0.27 0.1 0.0e+00 0.18 0.19 0.19 0.2 4.0e-20 7.7e-22 9.5e-22 1.9e-22

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.20.30.7-0.40.8-0.70.80.60.6-0.50.40.40.60.5-0.30.4
Area under the delay curve0.40.41.6-1.30.7-0.60.70.80.7-0.20.70.70.7-0.40.00.4
BMI with tail0.62.06.31.2-1.81.1-1.3-0.7-0.82.50.50.50.5-2.22.20.5
BMI without tail0.10.21.11.0-0.40.0-0.2-0.4-0.30.2-0.3-0.3-0.5-0.40.0-0.7
Body weight0.83.26.92.5-2.62.6-2.3-1.9-1.92.3-0.7-0.8-0.6-0.71.6-0.2
Weight adjusted by age1.11.22.10.5-0.61.0-1.0-1.4-1.1-0.6-1.4-1.4-1.41.1-1.0-1.1
Bone surface0.40.62.10.5-0.00.3-0.4-0.5-0.7-0.7-1.2-1.0-0.51.4-0.9-0.9
Bone volume0.10.20.60.4-0.10.2-0.3-0.4-0.5-0.4-0.7-0.6-0.20.8-0.5-0.5
Breakpoint value in progressive ratio session0.40.40.9-0.10.4-0.80.60.60.70.20.80.70.6-0.60.50.9
Number of licking bursts0.20.31.3-1.10.5-0.50.50.40.4-0.6-0.0-0.0-0.20.4-0.5-0.2
Context. condit. distance diff. score4.04.810.22.7-3.23.0-2.9-2.6-2.72.1-1.5-1.6-1.60.01.1-0.5
Locomotion velocity, session 11.31.43.00.6-0.81.1-1.0-1.2-1.3-0.5-1.7-1.6-1.11.4-0.9-1.5
Locomotion distance, session 10.91.23.7-1.41.2-0.80.70.40.5-1.9-0.6-0.6-0.51.2-1.8-1.0
Locomotion velocity, session 20.50.61.30.8-0.80.7-1.1-0.9-1.20.2-1.0-0.9-0.4-0.2-0.1-0.9
Locomotion distance, session 22.13.07.1-2.72.2-2.22.12.02.0-1.11.41.51.6-0.6-0.40.8
Locomotion velocity, session 31.21.42.31.0-0.91.1-1.3-1.3-1.4-0.3-1.5-1.5-1.11.0-0.8-1.4
Locomotion distance, session 30.80.82.7-0.70.7-0.30.30.00.0-1.6-0.7-0.8-1.01.1-1.6-1.2
Stereotopy head waving bouts, day 30.60.71.41.0-1.11.2-1.1-0.9-1.10.8-0.8-0.6-0.00.20.5-0.2
Stereotopy head waving duration, day 33.03.66.92.6-2.52.5-2.5-2.3-2.41.5-1.8-1.6-0.90.40.7-0.8
Locomotion velocity, session 70.20.20.70.2-0.40.5-0.5-0.5-0.6-0.1-0.5-0.5-0.3-0.3-0.3-0.8
Locomotion distance, session 71.01.22.3-1.50.9-0.91.01.21.10.01.41.31.5-1.30.40.8
Stereotopy head waving bouts, day 75.96.69.83.1-2.73.1-2.9-3.0-3.10.6-3.1-2.9-2.32.0-0.5-2.0
Stereotopy head waving duration, day 74.65.69.83.1-2.42.7-2.6-2.7-2.80.4-2.8-2.7-2.31.7-0.6-2.0
Locomotion velocity, session 81.41.74.11.0-2.01.6-1.8-1.6-1.61.6-1.0-0.9-0.9-0.11.10.2
Locomotion distance, session 80.71.01.91.1-1.41.1-1.4-1.2-1.30.8-0.9-0.9-0.80.20.3-0.3
Degree of sensitization distance2.02.05.40.3-0.70.2-0.20.30.32.21.51.41.7-2.22.31.7
Degree of sensitization stereotypy4.85.27.62.6-2.32.7-2.4-2.6-2.60.2-2.8-2.7-2.42.0-0.8-1.9
Conditioned locomotion0.91.11.71.2-1.11.2-1.2-1.3-1.20.2-1.0-1.2-1.10.8-0.3-0.8
Cocaine response after cond. corrected0.20.20.50.4-0.30.2-0.4-0.5-0.4-0.1-0.5-0.5-0.50.2-0.3-0.7
Cocaine response after cond. not corrected0.30.40.80.6-0.40.1-0.6-0.6-0.7-0.2-0.8-0.8-0.70.3-0.5-0.9
Cocaine response before conditioning0.00.00.1-0.00.2-0.4-0.10.2-0.1-0.3-0.1-0.1-0.1-0.0-0.2-0.2
Saline control response1.51.93.71.4-0.90.9-1.3-1.4-1.6-0.5-1.7-1.7-1.61.9-0.9-1.4
Bone: connectivity density0.10.20.4-0.30.6-0.30.60.60.5-0.30.30.40.60.5-0.10.4
Bone: cortical apparent density0.50.61.6-1.31.0-0.71.00.90.9-0.70.60.60.70.3-0.30.3
Bone: cortical area0.91.42.81.5-1.71.6-1.5-1.4-1.41.4-0.7-0.6-0.4-0.41.0-0.2
Bone: cortical porosity0.50.51.61.3-0.80.7-1.0-0.7-0.90.5-0.6-0.6-0.40.40.2-0.4
Bone: cortical porosity1.01.13.01.7-1.31.1-1.4-1.1-1.30.9-0.8-0.8-0.60.30.5-0.5
Bone: cortical thickness0.81.43.1-0.90.1-0.40.50.80.91.31.51.51.2-1.81.61.5
Bone: cortical thickness1.01.23.0-0.7-0.1-0.30.40.80.71.31.41.30.8-1.71.51.5
Bone: cortical tissue density0.50.61.7-1.31.0-0.71.00.90.9-0.60.70.60.70.3-0.30.4
Condit. Reinf. active minus inactive responses0.60.71.9-1.20.8-0.80.70.90.70.00.90.91.4-0.90.40.7
Condit. Reinf. active-inactive response ratio0.10.20.30.3-0.50.6-0.5-0.4-0.50.5-0.3-0.20.3-0.40.3-0.1
Condit. Reinf. active responses1.41.83.2-1.71.7-1.81.41.61.4-0.71.21.31.5-0.9-0.10.7
Condit. Reinf. inactive responses1.92.24.9-1.72.1-2.21.81.91.7-1.41.31.21.1-0.4-0.70.5
Incentive salience index mean1.31.63.3-1.71.3-1.31.21.41.2-0.11.31.41.8-1.20.40.9
Condit. Reinf. lever presses0.91.22.3-1.41.4-1.41.11.31.1-0.50.91.11.5-1.0-0.00.4
Condit. Reinf. active minus inactive responses0.70.92.0-1.40.3-0.40.60.70.70.70.91.01.3-0.91.01.3
Condit. Reinf. active-inactive response ratio1.21.22.9-1.10.3-0.40.70.90.81.01.21.31.7-1.11.31.6
Condit. Reinf. active responses0.20.31.0-0.3-0.80.7-0.6-0.5-0.51.0-0.10.00.4-0.40.90.6
Condit. Reinf. inactive responses0.70.91.90.6-1.31.3-1.4-1.3-1.30.7-0.9-0.9-0.6-0.00.3-0.5
Condit. Reinf. lever presses0.40.51.3-1.10.7-0.80.90.80.8-0.00.50.71.1-0.00.30.8
Condit. Reinf. lever reinforcers received0.20.30.7-0.5-0.40.4-0.2-0.1-0.10.80.10.30.8-0.30.80.8
Conditioned reinforcement - actives0.30.30.8-0.7-0.80.9-0.8-0.8-0.70.4-0.4-0.5-0.4-0.10.1-0.4
Conditioned reinforcement - inactives0.81.02.5-1.60.5-0.40.70.91.00.51.11.11.1-0.90.81.2
Conditioned locomotion0.81.02.80.4-1.41.2-1.1-0.7-0.81.70.20.10.3-1.41.40.5
Patch foraging indifference point 0 sec0.40.61.3-0.40.9-1.11.01.11.0-0.20.80.90.90.00.30.8
Patch foraging indifference point AUC0.10.10.3-0.60.3-0.40.30.20.2-0.30.00.10.20.3-0.2-0.3
Delay disc. indifference point, 0s delay0.40.41.10.4-0.80.5-0.7-0.4-0.51.10.30.20.3-0.90.90.7
Delay disc. indifference point, 16s delay1.01.02.3-0.91.5-1.31.51.31.4-1.10.70.70.70.4-0.70.0
Delay disc. indifference point, 2s delay0.20.20.9-0.90.0-0.0-0.00.20.20.40.60.50.7-0.80.50.4
Delay disc. indifference point, 24s delay0.30.30.8-0.40.10.5-0.1-0.2-0.3-0.7-0.6-0.6-0.50.9-0.8-0.8
Delay disc. indifference point, 4s delay1.01.02.1-1.40.5-0.60.70.90.80.71.21.31.4-1.01.01.2
Delay disc. indifference point, 8s delay0.80.82.0-1.41.2-1.11.11.11.1-0.70.80.70.7-0.1-0.40.3
Indifference point function ln k0.50.81.51.2-1.21.2-1.2-0.8-1.01.0-0.5-0.5-0.4-0.30.60.5
Indifference point function log k0.50.81.51.2-1.21.2-1.2-0.8-1.01.0-0.5-0.5-0.4-0.30.60.5
Patch foraging total patch changes 0 sec0.50.81.5-0.51.1-1.21.11.21.1-0.30.90.90.90.20.20.7
Patch foraging total patch changes 12 sec0.20.21.0-0.30.2-0.40.20.50.30.40.70.51.0-0.10.60.2
Patch foraging total patch changes 18 sec0.50.61.4-0.50.6-0.70.90.80.90.31.01.01.2-0.30.71.0
Patch foraging total patch changes 24 sec0.10.20.30.40.6-0.60.50.30.5-0.40.20.20.30.3-0.2-0.3
Patch foraging total patch changes 6 sec0.20.40.9-0.80.6-1.00.60.70.60.10.60.70.6-0.30.40.0
Patch foraging time to switch 0 sec0.10.10.30.50.20.10.0-0.1-0.1-0.4-0.0-0.30.20.2-0.4-0.5
Patch foraging water rate 0 sec0.20.30.8-0.40.3-0.90.50.50.60.20.30.6-0.0-0.30.50.7
Patch foraging water rate 12 sec0.10.20.80.90.4-0.40.30.10.2-0.6-0.3-0.2-0.40.6-0.6-0.3
Patch foraging water rate 18 sec0.40.51.3-0.21.1-1.00.70.70.5-1.2-0.2-0.1-0.10.9-0.90.1
Patch foraging water rate 24 sec0.10.10.30.2-0.2-0.10.10.00.20.5-0.00.20.3-0.30.60.1
Patch foraging water rate 6 sec0.60.82.70.10.6-0.30.2-0.2-0.2-1.4-1.1-0.8-0.61.6-1.4-1.1
Seeking ratio, delayed vs. immediate footshock2.83.26.2-1.52.5-2.52.42.52.3-1.41.41.51.60.3-0.60.3
Distance traveled before self-admin2.22.33.8-1.60.8-1.31.31.61.60.82.01.92.0-1.61.31.3
Distance traveled after self-admin0.40.41.1-0.30.1-0.30.20.60.40.80.70.91.0-0.61.00.7
Extensor digitorum longus weight0.10.20.50.10.5-0.60.40.10.1-0.7-0.3-0.2-0.70.7-0.6-0.6
Bone: elastic displacement1.31.52.61.4-0.91.1-1.1-1.3-1.3-0.3-1.5-1.5-1.61.0-0.8-1.3
Bone: elastic work1.51.94.72.2-1.91.7-1.7-1.5-1.61.5-1.0-0.9-0.8-0.40.9-0.2
Bone: endosteal estimation3.06.510.63.2-2.42.5-2.9-3.1-3.20.1-3.3-3.0-2.31.9-0.9-2.4
Bone: endosteal perimeter4.28.715.23.9-3.03.3-3.4-3.6-3.60.5-3.5-3.3-2.61.8-0.8-2.7
Epididymis fat weight2.35.410.63.0-3.13.3-3.1-2.9-2.81.8-1.7-1.8-1.4-0.40.8-1.7
Delta time in closed arm before/after self-admin0.60.61.9-0.3-0.90.4-0.7-0.3-0.31.40.50.50.6-1.31.30.6
Delta time in open arm before/after self-admin0.50.51.10.70.10.3-0.1-0.4-0.4-0.9-0.6-0.9-0.91.0-1.1-0.5
Diff in mean of infusions in LGA sessions0.91.04.6-2.20.9-1.11.01.01.0-0.30.80.80.8-0.20.00.7
Delay discount exponential model param0.40.41.91.4-0.70.6-0.7-0.7-0.60.3-0.6-0.6-0.70.20.1-0.3
Extinction: sum of active levers before priming0.20.20.4-0.70.1-0.50.20.30.30.20.50.40.3-0.50.30.6
Active lever presses in extinction session 60.20.20.5-0.5-0.2-0.4-0.1-0.10.00.50.30.30.2-0.70.60.6
Bone: final force0.71.23.90.1-1.00.7-0.6-0.2-0.22.00.80.81.1-1.31.91.4
Bone: final moment0.81.24.30.3-1.20.9-0.7-0.4-0.42.10.60.70.9-1.22.01.3
Food consumed during 24 hour testing period0.70.82.5-0.4-1.11.0-0.8-0.4-0.61.60.40.30.3-1.21.40.7
Glucose0.30.50.9-0.41.0-1.00.80.90.8-0.40.70.70.9-0.2-0.10.1
Heart weight1.31.95.91.3-1.61.1-1.1-0.4-0.62.40.70.70.2-1.82.31.3
Delay discount hyperbolic model param0.30.41.71.3-0.50.4-0.5-0.6-0.50.1-0.7-0.6-0.70.4-0.1-0.4
Intermittent access intake day 1-15 change0.20.20.7-0.20.7-0.60.80.60.7-0.40.40.40.30.0-0.2-0.1
Intermittent access intake escalation0.30.30.8-0.10.7-0.60.90.70.8-0.40.40.40.30.1-0.2-0.1
Intermittent access intake escalation 20.10.10.10.20.3-0.10.30.10.2-0.4-0.1-0.1-0.10.3-0.3-0.2
Intermitt. access day 1 inactive lever presses1.01.13.2-0.4-0.1-0.10.40.60.61.31.11.21.1-1.41.51.8
Intermitt. access day 15 inactive lever presses2.52.85.5-1.5-0.1-0.60.81.21.11.91.91.91.9-2.22.32.4
Intermitt. access escalation Index0.40.30.6-0.60.4-0.50.60.60.70.30.70.80.8-0.40.50.7
Intermittent access day 1 total infusions0.50.51.6-0.3-0.80.9-0.6-0.4-0.41.30.40.30.5-1.01.10.7
Intermittent access day 15 total infusions0.30.40.7-0.70.2-0.10.50.60.70.50.80.80.8-0.60.70.5
Intermittent access terminal intake (last 3 days)0.00.00.2-0.1-0.20.4-0.1-0.1-0.00.30.20.10.1-0.20.20.0
Intermittent access total infusions0.20.20.6-0.4-0.30.5-0.10.00.10.70.50.50.5-0.70.70.5
Intermittent access day 1 locomotion0.40.41.0-0.6-0.30.2-0.20.00.10.90.50.50.7-1.00.90.9
Intermittent access day 15 total locomotion0.10.10.5-0.0-0.20.4-0.10.00.00.40.20.20.3-0.20.40.7
Intermittent access total locomotion0.40.51.0-0.5-0.30.2-0.10.30.21.00.70.70.9-1.01.00.9
Intermittent access standard deviation0.60.71.70.8-0.40.40.00.20.31.20.90.80.8-1.31.30.7
Left kidney weight6.217.639.84.3-6.35.8-5.5-4.6-4.85.7-1.9-1.9-1.1-2.14.10.3
Right kidney weight6.418.040.64.2-6.45.7-5.6-4.4-4.76.1-1.4-1.5-0.9-2.74.60.5
Cocaine induced anxiety0.91.02.6-0.5-0.3-0.30.30.40.61.41.31.21.1-1.61.60.9
Post-drug Anxiety0.20.20.8-0.3-0.2-0.30.30.10.30.80.60.50.4-0.60.90.5
Baseline Anxiety0.70.72.1-0.60.7-0.40.20.1-0.1-1.4-0.8-0.7-0.81.4-1.4-0.7
Tail length0.20.61.20.80.2-0.00.1-0.3-0.1-1.0-0.8-0.8-1.11.1-1.1-0.8
Length with tail0.41.53.31.8-1.41.8-1.4-1.5-1.40.5-1.3-1.2-0.90.90.0-0.5
Length without tail0.51.02.90.7-1.41.7-1.3-0.9-1.11.5-0.2-0.20.5-0.11.20.5
Times rat made contact with spout0.40.51.3-0.6-0.70.4-0.4-0.1-0.21.10.50.40.1-1.11.10.7
Lifetime Intake0.91.02.5-0.5-0.40.40.00.30.41.51.11.11.2-1.51.61.3
Liver weight, left1.82.85.42.3-1.62.2-1.9-2.0-1.90.2-1.8-1.8-1.21.4-0.6-1.5
Liver weight, right3.05.09.03.0-2.52.9-2.7-2.8-2.70.7-2.2-2.3-1.71.1-0.3-2.1
Locomotor activity1.52.44.61.5-2.12.1-2.1-2.0-2.01.3-1.4-1.4-1.10.20.6-0.7
Locomotor testing distance0.00.00.1-0.20.00.1-0.0-0.1-0.0-0.2-0.2-0.20.00.4-0.2-0.2
Locomotor testing rearing0.91.32.81.0-1.71.7-1.7-1.5-1.41.1-0.8-0.8-0.7-0.40.6-0.6
Locomotion in novel chamber2.43.05.62.1-0.40.8-0.9-1.6-1.3-1.6-2.1-2.2-2.41.4-2.1-2.1
Locomotion in novel chamber post-restriction0.40.51.50.11.0-0.80.80.70.6-1.20.0-0.0-0.00.6-1.1-0.5
Fecal boli incidents, locomotor time 10.30.31.1-1.00.7-0.90.70.30.6-0.50.30.30.20.1-0.30.2
Change in fecal boli incidents, locomotor task1.31.32.91.0-1.11.7-1.1-1.3-1.30.1-1.3-1.2-1.20.9-0.4-1.1
Time >=10cm from walls, locomotor time 10.00.00.20.4-0.10.1-0.2-0.1-0.20.20.10.00.4-0.00.20.2
Bouts of movement, locomotor time 10.10.10.4-0.7-0.10.10.10.30.00.30.40.30.4-0.60.30.1
Total resting periods, locomotor time 10.50.61.1-1.00.4-0.50.60.90.70.31.10.90.9-1.00.50.7
Rest time, locomotor task time 11.41.54.1-0.70.3-0.70.81.01.01.01.71.51.5-2.01.31.3
Distance moved, locomotor task time 11.01.12.11.1-1.11.4-1.5-1.4-1.40.3-1.2-1.1-0.80.6-0.1-0.4
Vertical activity count, locomotor time 10.10.10.40.1-0.20.4-0.3-0.3-0.3-0.0-0.4-0.3-0.10.6-0.1-0.0
Time >=10cm from walls, locomotor time 20.10.10.40.60.2-0.10.1-0.1-0.1-0.5-0.2-0.2-0.10.5-0.5-0.2
Bouts of movement, locomotor time 20.91.02.0-1.30.1-0.30.50.70.70.91.31.21.3-1.41.21.0
Total resting periods, locomotor time 21.21.22.4-1.50.3-0.40.60.90.90.91.41.41.4-1.51.21.1
Rest time, locomotor task time 20.40.52.1-1.50.6-0.60.80.80.7-0.10.70.70.6-0.50.20.2
Distance moved, locomotor task time 20.91.02.21.5-1.31.3-1.5-1.3-1.30.6-0.8-0.9-0.8-0.00.2-0.2
Vertical activity count, locomotor time 20.60.72.41.6-0.91.0-0.9-1.0-0.90.4-0.7-0.7-0.70.40.1-0.1
Light reinforcement 11.01.85.52.4-0.90.9-1.3-1.4-1.5-0.3-1.7-1.6-1.01.5-0.8-1.1
Light reinforcement 20.50.72.51.6-1.00.8-1.1-1.0-1.10.6-0.6-0.60.00.10.2-0.4
Bone: marrow area3.16.810.93.3-2.42.5-3.0-3.2-3.20.2-3.3-3.0-2.31.9-0.9-2.3
Bone: maximum diameter3.25.810.93.2-3.33.2-3.2-3.0-3.02.2-2.0-1.8-1.30.01.2-0.9
Bone: maximum force1.11.96.10.9-1.81.4-1.4-1.0-1.02.50.20.30.5-1.52.21.0
Bone: maximum moment1.22.16.71.1-2.01.5-1.6-1.2-1.22.60.00.20.4-1.52.20.9
Mean time between licks in bursts0.30.51.0-1.00.9-0.90.90.70.9-0.70.60.50.00.4-0.50.1
Mean num. licks in bursts0.70.92.00.9-1.41.3-1.2-0.9-0.91.4-0.1-0.1-0.1-0.91.10.3
Cd content in liver1.11.33.41.2-1.51.2-1.4-1.3-1.20.7-0.8-1.0-1.9-0.20.2-0.8
Co content in liver0.20.30.8-0.2-0.60.0-0.4-0.3-0.10.90.40.3-0.3-0.50.90.8
Cu content in liver1.92.35.6-1.32.4-2.02.11.61.7-2.00.60.81.01.0-1.30.2
Fe content in liver0.60.72.21.5-0.50.6-0.8-0.8-0.9-0.1-1.1-0.9-0.51.0-0.4-0.4
K content in liver0.80.81.9-0.91.0-1.11.00.91.0-0.20.70.91.4-0.60.20.8
Mg content in liver1.91.94.6-1.31.6-1.51.61.61.6-0.21.41.62.1-0.60.51.2
Mn content in liver0.40.40.80.5-0.60.6-0.9-0.9-0.8-0.0-0.8-0.8-0.50.4-0.3-0.9
Na content in liver1.51.63.6-1.41.9-1.81.71.41.5-1.50.80.80.70.4-1.00.4
Rb content in liver0.10.10.4-0.30.1-0.10.20.20.30.30.40.40.6-0.10.40.4
Se content in liver0.30.41.4-0.20.7-0.50.30.10.2-1.2-0.4-0.4-0.10.9-1.1-0.7
Sr content in liver0.50.51.4-1.20.9-1.00.80.60.8-0.90.40.4-0.5-0.3-0.6-0.1
Zn content in liver0.50.62.0-0.30.9-0.60.60.30.3-1.3-0.4-0.4-0.41.4-1.2-0.5
Bone: minimum diameter1.32.44.52.1-1.61.6-1.8-2.0-1.90.4-1.9-1.7-1.20.7-0.3-1.5
Time in familiar zone, hab. session 10.20.20.40.0-0.40.5-0.4-0.5-0.4-0.1-0.5-0.5-0.4-0.1-0.3-0.7
Time in novel zone, hab. session 10.80.82.11.4-1.00.7-1.0-1.0-1.00.5-0.8-0.7-1.30.50.2-0.2
Total zone transitions, hab. session 11.41.95.6-1.81.7-1.31.20.80.8-2.4-0.5-0.4-0.51.6-2.1-1.0
Total locomotion distance, hab. session 11.82.56.20.00.5-0.1-0.3-0.6-0.8-2.2-2.0-1.9-1.62.2-2.5-2.3
Locomotion velocity, hab. session 11.21.75.0-0.40.9-0.60.2-0.0-0.3-2.2-1.4-1.3-0.91.7-2.2-1.8
Time in familiar zone, hab. session 21.31.32.81.4-0.60.8-0.9-0.9-1.0-0.8-1.3-1.4-1.60.9-1.2-1.7
Time in novel zone, hab. session 20.50.51.5-0.90.0-0.40.30.30.40.80.70.80.7-0.51.11.2
Total zone transitions, hab. session 20.40.52.3-1.50.9-0.80.70.60.6-0.60.30.30.60.3-0.30.4
Total locomotion distance, hab. session 20.30.31.0-1.00.8-1.00.70.60.5-0.70.10.20.3-0.0-0.5-0.0
Locomotion velocity, hab. session 20.50.71.6-1.21.2-1.30.90.80.7-1.10.10.20.40.1-0.8-0.2
Novel to familiar place preference ratio2.93.05.32.1-2.12.3-2.0-2.1-1.91.0-1.7-1.6-2.01.10.3-0.6
Novelty place preference3.93.97.02.4-2.52.6-2.3-2.4-2.21.2-1.9-1.8-2.31.10.3-0.9
Time in novel zone, NPP test4.54.68.32.6-2.82.9-2.6-2.7-2.51.4-2.0-1.9-2.51.10.4-0.9
Total zone transitions, NPP test1.01.43.8-1.81.4-1.11.00.70.7-2.0-0.4-0.4-0.51.4-1.7-0.7
Total locomotion distance, NPP test0.50.71.7-1.31.1-1.00.80.60.5-1.3-0.1-0.1-0.10.6-1.0-0.3
Locomotion velocity, NPP test0.81.23.1-1.41.5-1.31.10.90.8-1.8-0.1-0.1-0.00.8-1.5-0.7
Intraocular pressure0.20.31.00.3-0.81.0-0.8-0.7-0.70.3-0.6-0.6-0.60.00.0-0.2
Delta distance traveled before/after self-admin1.92.03.21.7-1.41.6-1.7-1.7-1.80.2-1.7-1.6-1.51.1-0.4-0.9
Delta ambulatory time before/after self-admin1.92.13.61.3-1.51.7-1.8-1.9-1.90.3-1.9-1.7-1.61.1-0.3-0.8
Parametrial fat weight0.20.30.8-0.4-0.0-0.20.00.40.20.60.80.70.6-0.90.80.8
Pavlov. Cond. lever latency1.01.32.31.5-1.51.5-1.2-1.4-1.20.7-0.9-1.0-1.50.70.2-0.4
Pavlov. Cond. magazine entry latency1.92.44.1-2.01.6-1.91.61.91.7-0.41.71.71.6-1.40.30.9
Pavlov. Cond. change in total contacts2.83.05.4-2.31.7-2.01.72.11.8-0.21.91.91.9-1.80.51.3
Pavlov. Cond. index score1.92.43.9-2.01.4-1.61.31.81.60.11.81.81.9-1.80.81.2
Pavlov. Cond. latency score1.62.03.1-1.71.2-1.51.21.61.40.11.71.61.7-1.60.71.1
Pavlov. Cond. lever contacts1.92.23.8-1.91.8-1.91.51.81.6-0.71.51.51.7-1.30.00.7
Pavlov. Cond. magazine entry number1.62.03.92.0-1.41.5-1.4-1.8-1.50.2-1.7-1.6-1.41.5-0.4-0.9
Pavlov. Cond. intertrial magazine entries0.60.81.6-1.21.2-1.01.21.01.1-0.60.70.70.60.3-0.20.6
Pavlov. Cond. lever-magazine prob. diff.2.02.44.3-2.11.5-1.71.41.81.6-0.11.81.81.9-1.70.51.1
Pavlov. Cond. response bias2.42.94.8-2.21.7-1.91.62.01.8-0.31.91.92.0-1.60.41.2
Pavlov. Cond. lever latency0.50.71.40.7-1.21.2-1.1-1.1-0.90.6-0.4-0.6-1.1-0.30.1-0.8
Pavlov. Cond. magazine entry latency4.95.79.3-2.82.9-2.83.02.83.0-0.92.32.52.7-0.50.22.1
Pavlov. Cond. change in total contacts2.43.27.8-1.61.5-1.61.82.01.80.51.82.12.8-0.91.32.5
Pavlov. Cond. index score2.93.76.1-2.32.3-2.32.52.32.3-0.71.71.92.3-0.30.31.9
Pavlov. Cond. latency score3.84.77.4-2.62.6-2.52.72.62.6-0.72.02.22.5-0.50.32.1
Pavlov. Cond. lever contacts0.81.12.4-0.91.3-1.31.31.31.1-0.40.70.91.60.10.21.1
Pavlov. Cond. magazine entry number3.34.06.62.3-2.32.1-2.5-2.3-2.40.5-1.9-2.1-2.60.6-0.4-2.1
Pavlov. Cond. intertrial magazine entries1.21.64.80.3-1.61.0-1.2-0.6-0.72.20.60.4-0.2-2.21.90.9
Pavlov. Cond. lever-magazine prob. diff.2.73.55.8-2.12.3-2.22.42.22.2-0.81.61.82.3-0.10.11.7
Pavlov. Cond. response bias1.52.04.2-1.41.6-1.61.71.71.6-0.31.21.42.0-0.20.41.6
Time in closed arm before self-admin2.83.17.5-1.32.6-2.72.42.32.1-2.10.71.00.71.0-1.3-0.4
Time in closed arm after self-admin0.20.20.40.2-0.50.0-0.6-0.3-0.40.6-0.00.10.2-0.70.6-0.5
Time in open arm before self-admin0.50.51.00.6-0.40.8-0.6-0.8-0.7-0.4-1.0-0.8-0.70.5-0.7-0.8
Time in open arm after self-admin0.91.02.21.30.10.5-0.2-0.6-0.5-1.2-1.0-1.2-1.11.4-1.5-0.8
Bone: periosteal estimation2.65.39.43.1-2.62.6-2.9-2.9-2.90.9-2.6-2.4-1.81.0-0.1-1.7
Bone: periosteal perimeter4.37.213.83.7-3.23.3-3.4-3.4-3.31.4-2.7-2.6-2.00.80.2-1.9
Bone: post-yield work0.30.41.1-0.4-0.3-0.1-0.10.00.11.00.50.60.5-1.01.10.9
Progressive ratio test 1 active lever presses0.91.02.4-0.7-0.10.10.30.60.71.11.21.11.2-1.61.31.3
Progressive ratio test 1 breakpoint0.60.61.6-0.7-0.00.10.20.40.50.80.90.90.9-1.30.91.0
Progressive ratio test 1 inactive lever presses2.72.95.8-0.90.3-0.61.01.31.41.62.22.12.1-2.42.12.3
Progressive ratio test 2 active lever presses1.21.32.4-1.60.6-0.60.91.11.20.61.51.41.4-1.21.01.2
Progressive ratio test 2 breakpoint1.41.62.6-1.60.4-0.60.91.11.20.91.61.51.5-1.61.31.4
Progressive ratio test 2 inactive lever presses2.73.25.0-2.21.2-1.41.81.92.00.72.22.22.0-1.51.41.8
Incentive Sensitization - Responses1.11.11.8-1.30.8-0.81.11.21.30.31.31.21.1-0.90.71.1
Incentive Sensitization - Breakpoint1.21.22.1-1.30.6-0.81.01.11.30.51.41.31.2-1.11.01.2
Sum of active levers in priming session hrs 5-60.10.10.30.20.3-0.50.20.30.3-0.10.30.20.2-0.1-0.00.4
Progressive ratio0.30.41.4-1.20.5-0.70.60.70.60.00.50.60.5-0.30.30.3
Food seeking constrained by brief footshock0.70.92.1-0.0-1.41.4-1.2-1.0-1.11.4-0.3-0.20.1-0.91.00.3
Seeking ratio, punishment vs. effort0.40.41.00.8-0.91.0-0.8-0.8-0.70.9-0.1-0.20.0-0.50.60.3
Retroperitoneal fat weight1.65.411.62.7-3.43.3-3.2-2.6-2.72.9-0.9-1.0-0.4-1.32.0-0.5
Reaction time number correct0.91.33.9-0.20.7-0.20.3-0.1-0.1-1.9-1.2-1.0-0.91.9-2.0-1.5
Reaction time mean minus median0.40.62.10.3-0.80.6-0.9-0.7-0.90.1-0.5-0.8-1.40.6-0.2-0.8
Reaction time mean minus median AUC0.40.61.50.2-1.11.0-1.0-0.7-0.90.6-0.3-0.6-1.20.10.2-0.6
Reaction time num false alarms1.11.52.60.9-0.70.6-1.1-1.2-1.3-0.7-1.5-1.6-1.61.5-1.2-1.6
Reaction time num false alarms AUC1.21.63.00.7-0.60.5-1.0-1.1-1.3-0.8-1.5-1.7-1.61.6-1.3-1.7
Reaction time trials correct on left0.91.33.9-0.20.7-0.20.3-0.1-0.1-1.9-1.2-1.0-0.91.9-2.0-1.5
Reaction time trials on left1.01.44.2-0.20.8-0.20.3-0.1-0.1-1.9-1.2-1.1-0.91.9-2.1-1.6
Reaction time mean0.10.10.2-0.50.3-0.30.30.40.3-0.20.30.2-0.10.3-0.1-0.1
Reaction time mean AUC0.10.10.3-0.60.3-0.30.30.40.4-0.20.30.2-0.10.0-0.1-0.1
Median of all reaction times0.20.30.7-0.80.7-0.70.80.70.8-0.40.60.50.40.1-0.10.2
Reaction time omissions0.30.41.1-0.70.2-0.10.1-0.0-0.1-0.8-0.4-0.5-1.00.6-0.8-1.0
Reaction time false alarm rate0.30.40.80.5-0.80.4-0.9-0.8-0.90.3-0.5-0.7-0.90.3-0.0-0.7
Reaction time premature initiation rate0.50.61.9-0.40.7-1.10.80.90.60.10.60.81.4-0.20.50.9
Reaction time premature initiations0.30.41.0-0.50.9-1.00.80.80.6-0.50.20.41.00.5-0.20.2
Std. dev. reaction times0.40.61.20.5-1.00.9-1.0-0.8-1.00.5-0.5-0.7-1.10.30.1-0.5
Reaction time trials completed1.01.44.2-0.20.8-0.20.3-0.1-0.1-1.9-1.2-1.1-0.91.9-2.1-1.6
Reaction time trials AUC0.91.23.5-0.30.6-0.10.2-0.1-0.2-1.7-1.2-1.1-0.81.9-1.9-1.5
Run reversals in cocaine runway, females1.21.13.00.30.30.2-0.3-0.5-0.7-1.5-1.2-1.2-0.91.7-1.7-1.5
Run reversals in cocaine runway, males1.41.42.60.8-1.21.6-1.4-1.5-1.50.2-1.3-1.3-1.30.6-0.3-1.2
Latency to leave start box in cocaine runway0.10.10.70.8-0.30.1-0.3-0.2-0.20.40.10.0-0.0-0.50.3-0.0
Latency to leave start box in cocaine runway, F0.20.20.40.40.5-0.60.30.20.2-0.6-0.2-0.0-0.10.5-0.5-0.5
Latency to leave start box in cocaine runway, M1.01.02.70.4-1.10.8-0.7-0.4-0.31.60.80.50.5-1.61.51.0
Std. dev. time between licks in bursts0.91.12.3-1.51.4-1.31.41.31.2-0.60.80.91.10.1-0.10.7
Total sessions with >9 infusions1.01.13.20.4-1.00.8-0.6-0.2-0.21.80.70.70.8-1.51.71.1
Short access day 1 total inactive lever presses0.70.82.70.4-1.00.8-0.7-0.3-0.41.60.30.40.5-1.21.51.0
Short access day 10 total inactive lever presses0.40.51.00.9-1.00.9-0.8-0.9-0.80.7-0.5-0.5-0.5-0.10.40.3
Short access day 1 total infusions1.21.33.90.4-1.10.8-0.6-0.3-0.22.00.80.80.9-1.71.91.4
Short access day 10 total infusions0.60.72.1-0.7-0.30.1-0.00.30.31.21.00.91.0-1.41.30.9
Short access total infusions2.02.36.1-0.1-0.90.5-0.20.10.32.41.61.41.5-2.52.52.0
Short access day 1 locomotion0.70.71.8-0.50.1-0.40.30.70.50.81.11.01.2-1.31.00.9
Short access day 10 total locomotion0.40.51.2-0.70.3-0.60.30.70.60.30.80.80.9-1.10.50.5
Short access total locomotion1.31.34.6-0.5-0.50.1-0.20.30.31.61.21.11.3-2.11.71.4
One hour access (0.3 mA shock)0.30.31.2-1.10.7-0.40.80.60.8-0.30.70.50.4-0.2-0.1-0.0
Compulsive drug intake0.80.81.7-0.91.2-1.11.20.71.0-1.30.10.1-0.21.0-1.0-0.5
One hour access (shock baseline)0.10.10.4-0.30.00.3-0.00.30.10.20.40.40.5-0.60.30.0
Social response proportion0.50.51.10.50.1-0.40.40.50.60.71.00.90.6-0.91.01.1
Social responses0.30.41.61.1-0.20.1-0.3-0.5-0.4-0.4-0.8-0.7-0.60.7-0.6-1.3
Social time1.41.83.7-1.61.8-1.91.61.81.7-1.11.21.11.0-0.2-0.50.1
Soleus weight0.20.52.5-1.60.6-0.80.70.60.7-0.00.60.70.6-0.20.31.0
Bone: stiffness0.71.13.50.8-1.20.9-0.9-0.7-0.61.90.40.40.6-1.31.70.8
Tibialis anterior weight0.72.44.4-2.11.8-2.12.11.82.0-0.71.61.60.8-0.30.01.0
Time to tail flick, vehicle, before self-admin0.50.61.20.1-0.60.5-0.8-0.8-1.0-0.2-1.0-1.0-1.10.6-0.5-0.7
Time to tail flick, vehicle, after self-admin2.42.55.00.80.10.3-0.5-1.2-1.0-1.9-1.9-1.9-2.02.2-2.2-2.2
Time to tail flick, test, before self-admin1.21.23.90.4-0.70.7-1.0-1.2-1.2-0.5-1.3-1.3-1.30.8-0.9-2.0
Time to tail flick, test, after self-admin0.50.61.6-0.71.0-0.70.80.70.6-1.3-0.1-0.1-0.10.8-1.1-0.6
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.20.5-0.40.50.40.5-0.20.30.30.30.0-0.1-0.2
Delta time to tail flick, test, before/after SA1.31.12.5-0.71.6-1.31.51.41.3-1.30.40.60.50.8-0.80.4
Tibia length0.41.23.51.2-1.61.9-1.3-1.2-1.21.4-0.7-0.6-0.20.61.00.3
Ambulatory time before self-admin1.31.42.6-0.70.7-0.91.11.31.30.61.61.61.5-1.31.11.2
Ambulatory time after self-admin0.20.21.6-1.30.5-0.50.40.50.4-0.20.10.30.30.40.0-0.0
Bone: tissue strength0.10.10.20.4-0.40.5-0.3-0.4-0.30.4-0.3-0.20.10.10.2-0.1
Total heroin consumption0.30.41.8-1.30.0-0.60.20.30.30.50.40.50.4-0.60.61.0
Bone: trabecular number0.20.31.00.6-0.10.4-0.3-0.4-0.4-0.4-0.5-0.6-0.41.0-0.6-0.6
Bone: trabecular spacing0.50.72.50.2-0.90.8-0.5-0.2-0.31.40.40.40.5-1.61.30.7
Bone: trabecular thickness0.10.10.50.10.4-0.70.30.10.2-0.40.10.10.30.4-0.30.0
Bone: trabecular tissue density1.11.53.8-1.41.6-1.91.61.51.5-0.71.11.10.7-0.1-0.10.9
Water consumed over 24 hours0.40.51.2-0.0-1.11.1-1.0-0.7-0.81.0-0.2-0.4-0.7-0.20.70.2
Number of responses in last shaping day2.82.94.2-1.91.5-2.01.92.02.00.12.02.02.0-1.30.91.4