Hub : Genes

Selenoo

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr7_122051488_122052585 0.04 0.03 4.3e-03 0 0.02 0.02 0.01 1.4e-01 6.2e-03 7.6e-03 1.4e-02
2 Adipose mRNA stability Selenoo 0.22 0.1 0.0e+00 0.12 0.17 0.15 0.17 9.0e-13 4.0e-18 4.8e-16 1.2e-18
3 LHb mRNA stability Selenoo 0.59 0.2 9.9e-05 0.13 0.13 0.16 0.17 4.8e-04 5.3e-04 1.6e-04 7.7e-05
4 Adipose gene expression Selenoo 0.31 0.12 0.0e+00 0.15 0.16 0.16 0.16 9.2e-17 6.0e-17 3.6e-17 5.2e-17
5 IC gene expression Selenoo 0.57 0.15 0.0e+00 0.47 0.5 0.5 0.49 5.5e-22 5.3e-24 7.7e-24 2.3e-23
6 Eye gene expression Selenoo 0.28 0.17 8.4e-03 0.04 0.06 0.03 0.03 8.8e-02 5.2e-02 1.3e-01 1.1e-01
7 Brain mRNA stability Selenoo 0.66 0.18 0.0e+00 0.39 0.4 0.37 0.4 4.7e-38 3.5e-39 1.4e-36 7.8e-40
8 pVTA gene expression Selenoo 0.5 0.14 0.0e+00 0.61 0.63 0.63 0.63 3.0e-61 9.5e-65 2.4e-64 3.1e-64
9 NAcc mRNA stability Selenoo 0.1 0.05 0.0e+00 0.14 0.15 0.14 0.14 2.6e-21 1.1e-21 1.4e-20 5.9e-21
10 NAcc gene expression Selenoo 0.22 0.09 0.0e+00 0.3 0.31 0.31 0.31 1.5e-46 1.4e-48 4.4e-48 6.2e-48
11 Liver mRNA stability Selenoo 0.13 0.07 2.5e-12 0.09 0.08 0.08 0.08 9.1e-10 3.1e-09 1.6e-09 2.9e-09
12 BLA mRNA stability Selenoo 0.21 0.11 1.1e-10 0.2 0.19 0.18 0.2 1.3e-10 4.0e-10 1.3e-09 7.5e-11
13 PL gene expression Selenoo 0.38 0.14 0.0e+00 0.43 0.45 0.45 0.45 4.0e-51 7.7e-55 2.8e-54 1.8e-54
14 BLA gene expression Selenoo 0.38 0.15 0.0e+00 0.34 0.32 0.32 0.33 6.3e-19 1.1e-17 1.9e-17 2.2e-18
15 OFC gene expression Selenoo 0.58 0.19 2.0e-11 0.49 0.5 0.5 0.51 2.4e-13 1.0e-13 9.6e-14 3.1e-14
16 IC mRNA stability Selenoo 0.3 0.14 1.3e-12 0.28 0.27 0.27 0.26 5.4e-12 8.5e-12 1.4e-11 1.6e-11
17 Brain intron excision ratio chr7_122051430_122054044 0.14 0.08 9.5e-14 0.16 0.16 0.14 0.15 1.1e-14 1.2e-14 2.0e-13 4.2e-14
18 LHb gene expression Selenoo 0.36 0.17 6.3e-06 0.21 0.2 0.18 0.19 9.9e-06 2.0e-05 3.8e-05 2.7e-05
19 IL mRNA stability Selenoo 0.23 0.15 1.9e-04 0.22 0.14 0.19 0.2 4.1e-06 2.9e-04 2.5e-05 1.3e-05
20 pVTA mRNA stability Selenoo 0.22 0.11 0.0e+00 0.28 0.29 0.29 0.29 3.7e-23 1.7e-23 1.5e-23 7.1e-24
21 IL gene expression Selenoo 0.41 0.17 8.0e-08 0.4 0.38 0.35 0.39 1.5e-10 5.9e-10 2.9e-09 2.2e-10
22 PL mRNA stability Selenoo 0.16 0.08 0.0e+00 0.22 0.21 0.2 0.21 2.3e-23 2.5e-22 5.7e-22 3.0e-22
23 Brain gene expression Selenoo 0.53 0.15 0.0e+00 0.52 0.55 0.56 0.56 5.0e-56 1.1e-60 7.8e-62 7.0e-62
24 OFC mRNA stability Selenoo 0.66 0.23 4.8e-09 0.38 0.42 0.43 0.4 7.6e-10 3.8e-11 1.9e-11 1.1e-10
25 Liver gene expression Selenoo 0.25 0.09 0.0e+00 0.2 0.22 0.22 0.22 5.1e-22 1.6e-24 1.3e-23 8.0e-24

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.22.02.9-1.2-1.3-1.5-0.9-1.4-1.4-1.7-1.4-1.5-1.5-0.4-1.6-1.4-1.5-1.6-1.71.7-1.7-1.6-1.5-1.5-1.0-1.5-1.0-1.4
Area under the delay curve0.60.81.8-0.20.1-0.41.0-0.6-0.6-0.6-0.8-0.8-0.81.0-0.8-0.9-0.9-1.0-0.90.9-0.9-0.9-1.0-0.9-1.0-1.2-0.9-1.3
BMI with tail4.615.819.74.44.44.43.44.44.34.24.24.24.23.14.04.24.04.03.9-3.93.93.93.93.93.83.83.73.1
BMI without tail2.26.88.22.52.22.61.12.82.82.82.82.82.80.82.72.82.72.82.7-2.92.82.82.82.72.82.92.42.6
Body weight1.87.910.23.23.13.02.43.13.12.93.13.03.02.03.22.92.82.72.7-2.62.62.62.72.62.92.72.52.2
Weight adjusted by age2.64.06.22.52.42.42.02.22.22.22.12.12.01.82.02.01.91.91.8-1.91.91.91.91.91.91.61.41.2
Bone surface1.01.93.4-0.6-0.5-1.10.4-1.1-1.1-1.5-1.3-1.3-1.40.7-1.5-1.3-1.6-1.6-1.61.8-1.8-1.7-1.4-1.5-1.0-1.7-1.1-1.8
Bone volume1.32.33.4-1.0-0.8-1.3-0.0-1.4-1.4-1.7-1.6-1.6-1.60.3-1.8-1.5-1.7-1.7-1.81.8-1.8-1.7-1.6-1.6-1.3-1.7-1.2-1.8
Breakpoint value in progressive ratio session0.20.31.40.70.90.51.20.50.50.30.40.40.41.00.60.30.30.10.3-0.10.10.10.20.00.50.20.3-0.1
Number of licking bursts0.10.10.4-0.3-0.3-0.5-0.7-0.2-0.2-0.4-0.1-0.2-0.1-0.5-0.1-0.2-0.1-0.3-0.10.3-0.3-0.4-0.1-0.5-0.0-0.1-0.0-0.0
Context. condit. distance diff. score1.92.33.41.20.91.40.01.51.51.71.61.61.6-0.11.71.61.61.71.5-1.81.81.81.61.71.61.81.31.7
Locomotion velocity, session 10.20.20.60.50.60.40.60.50.50.40.50.40.40.70.40.40.40.20.4-0.20.20.20.40.10.50.30.50.2
Locomotion distance, session 12.33.04.2-1.5-1.1-1.7-0.1-1.7-1.8-1.8-1.8-1.9-1.8-0.3-1.7-1.8-1.9-1.9-1.81.9-1.9-1.9-1.9-2.0-1.8-1.8-1.8-1.8
Locomotion velocity, session 20.70.81.61.11.20.90.71.11.00.91.00.91.00.90.81.00.90.80.9-0.80.80.80.90.51.10.71.20.6
Locomotion distance, session 21.11.52.0-1.0-0.9-1.3-0.1-1.2-1.2-1.3-1.2-1.3-1.3-0.2-1.2-1.3-1.4-1.4-1.21.4-1.4-1.4-1.2-1.4-1.2-1.4-1.4-1.3
Locomotion velocity, session 30.50.65.4-0.6-1.2-0.7-2.30.00.0-0.30.30.20.3-2.00.40.20.40.20.3-0.20.20.20.40.20.70.50.11.0
Locomotion distance, session 30.10.10.9-0.5-0.6-0.5-1.0-0.4-0.3-0.4-0.3-0.3-0.3-0.7-0.5-0.2-0.1-0.2-0.20.2-0.2-0.2-0.2-0.0-0.2-0.10.10.1
Stereotopy head waving bouts, day 31.61.93.4-1.1-0.9-1.1-0.1-1.5-1.4-1.2-1.6-1.5-1.6-0.0-1.8-1.5-1.6-1.4-1.51.3-1.4-1.3-1.5-1.4-1.5-1.6-1.1-1.6
Stereotopy head waving duration, day 30.60.71.2-0.9-1.0-0.8-0.5-1.0-1.0-0.7-1.0-0.9-1.0-0.6-1.1-0.9-1.0-0.8-0.80.7-0.7-0.7-0.9-0.8-0.9-0.8-0.7-0.7
Locomotion velocity, session 71.21.42.60.40.41.0-0.80.80.81.20.91.01.0-0.60.71.11.41.51.4-1.51.51.51.21.50.71.51.61.5
Locomotion distance, session 70.30.40.70.30.30.4-0.30.50.50.60.60.60.6-0.20.60.60.80.70.8-0.70.70.70.70.70.40.80.70.8
Stereotopy head waving bouts, day 71.31.52.2-1.0-1.4-1.5-0.6-1.2-1.2-1.4-1.1-1.2-1.2-0.6-1.2-1.2-1.4-1.4-1.41.3-1.3-1.3-1.2-1.4-0.8-1.2-1.2-1.1
Stereotopy head waving duration, day 71.31.53.0-1.4-1.7-1.6-1.3-1.3-1.3-1.4-1.2-1.2-1.2-1.3-1.4-1.2-1.3-1.2-1.21.2-1.1-1.2-1.1-1.2-0.8-1.0-1.0-0.8
Locomotion velocity, session 81.21.52.91.00.60.9-0.11.21.21.21.31.31.30.11.01.31.31.31.3-1.31.31.31.31.21.51.31.71.4
Locomotion distance, session 80.50.81.31.10.80.80.81.01.00.91.01.01.00.71.00.90.70.80.8-0.80.80.80.80.81.00.80.50.6
Degree of sensitization distance1.71.82.71.61.61.61.41.51.51.51.41.41.31.41.41.31.21.21.3-1.31.21.31.31.11.11.11.10.8
Degree of sensitization stereotypy0.40.41.3-0.7-1.1-1.0-0.9-0.5-0.5-0.8-0.4-0.5-0.4-1.0-0.3-0.5-0.6-0.6-0.50.6-0.6-0.6-0.4-0.60.0-0.3-0.6-0.2
Conditioned locomotion0.40.50.80.60.40.5-0.10.80.70.60.80.80.80.30.70.80.90.70.9-0.60.60.60.80.50.70.80.90.8
Cocaine response after cond. corrected1.21.41.91.20.91.10.31.31.31.31.31.31.30.41.21.31.21.21.2-1.41.41.21.31.21.41.31.31.1
Cocaine response after cond. not corrected2.73.24.61.71.31.60.21.91.91.81.91.91.90.51.91.91.81.91.8-1.91.91.81.91.92.11.91.81.8
Cocaine response before conditioning1.01.21.61.10.91.20.31.21.21.11.21.21.20.61.01.21.11.21.1-1.11.11.21.21.21.31.11.21.0
Saline control response0.81.13.51.61.61.31.61.21.21.11.01.00.91.90.90.90.70.70.8-0.70.70.70.90.61.00.50.90.1
Bone: connectivity density1.01.62.7-1.1-1.3-1.6-1.4-1.2-1.2-1.6-1.2-1.2-1.2-0.8-1.3-1.2-1.2-1.4-1.41.6-1.6-1.6-1.2-1.4-0.7-1.2-0.7-1.1
Bone: cortical apparent density2.43.34.1-2.0-1.8-1.9-1.3-2.0-2.0-2.0-2.0-1.9-2.0-1.5-1.9-1.9-1.8-1.8-2.01.8-1.8-1.7-1.9-1.7-1.8-1.7-1.7-1.4
Bone: cortical area0.91.45.71.62.01.62.41.11.11.20.90.90.92.10.61.00.80.90.7-0.80.80.90.71.10.40.61.10.1
Bone: cortical porosity0.50.52.41.31.30.81.20.80.80.40.70.60.61.50.60.60.40.30.3-0.00.00.20.30.30.60.10.5-0.2
Bone: cortical porosity1.01.03.41.81.71.11.71.31.20.71.11.01.01.81.10.90.60.50.6-0.30.30.40.60.61.00.30.6-0.0
Bone: cortical thickness0.10.21.30.40.80.71.20.20.20.50.10.20.10.70.00.30.20.40.0-0.30.30.40.00.7-0.30.10.2-0.0
Bone: cortical thickness1.21.43.30.51.01.51.00.70.81.60.71.00.90.30.61.11.21.61.3-1.71.71.70.91.80.01.41.21.2
Bone: cortical tissue density2.23.03.8-1.9-1.8-1.9-1.3-1.9-1.9-1.9-1.9-1.8-1.8-1.5-1.8-1.8-1.7-1.7-1.91.8-1.8-1.7-1.8-1.6-1.7-1.6-1.6-1.4
Condit. Reinf. active minus inactive responses1.92.23.91.81.91.81.21.61.51.61.41.41.41.80.91.51.41.41.4-1.41.41.41.41.31.31.22.00.8
Condit. Reinf. active-inactive response ratio0.20.20.80.50.40.5-0.00.50.50.40.40.40.40.50.10.50.40.40.5-0.40.40.50.50.50.50.30.90.3
Condit. Reinf. active responses2.83.55.42.22.22.11.52.02.02.01.81.91.92.01.41.91.81.81.8-1.81.81.81.81.71.71.72.31.2
Condit. Reinf. inactive responses1.82.23.31.71.81.61.51.61.61.61.51.51.51.61.41.51.41.41.4-1.41.41.31.41.21.41.41.61.0
Incentive salience index mean3.03.76.32.42.52.32.02.02.02.11.81.91.92.41.41.91.81.71.8-1.71.71.81.81.71.61.52.41.0
Condit. Reinf. lever presses2.23.15.12.22.32.11.81.91.91.91.71.71.72.21.41.81.61.61.7-1.61.61.61.71.51.51.32.00.9
Condit. Reinf. active minus inactive responses0.40.65.60.41.20.62.4-0.1-0.10.3-0.3-0.2-0.31.9-0.5-0.2-0.2-0.2-0.30.2-0.2-0.2-0.5-0.2-0.9-0.50.1-0.9
Condit. Reinf. active-inactive response ratio0.10.11.40.10.60.41.2-0.0-0.00.3-0.2-0.1-0.10.9-0.3-0.00.10.10.0-0.10.10.1-0.10.2-0.6-0.10.3-0.3
Condit. Reinf. active responses0.81.18.21.32.01.42.90.70.71.00.40.50.52.50.20.60.50.50.4-0.50.50.50.20.5-0.20.20.8-0.4
Condit. Reinf. inactive responses0.70.93.31.21.61.21.81.01.01.00.80.80.81.60.70.90.70.70.7-0.70.70.70.60.60.50.70.80.2
Condit. Reinf. lever presses1.52.17.21.92.31.82.71.51.51.41.31.31.32.31.01.31.31.11.2-1.01.01.01.11.20.80.91.40.5
Condit. Reinf. lever reinforcers received0.71.08.21.11.91.32.90.60.60.90.30.30.32.50.00.40.30.30.2-0.30.30.30.10.3-0.40.00.6-0.6
Conditioned reinforcement - actives0.50.91.71.31.31.11.31.11.11.01.00.90.91.30.90.90.80.81.0-0.70.70.70.90.70.70.70.60.3
Conditioned reinforcement - inactives0.20.20.50.50.40.40.20.50.50.50.60.50.50.10.70.50.60.50.5-0.50.50.50.50.50.50.60.40.5
Conditioned locomotion2.73.54.32.11.81.91.42.12.02.02.02.02.01.21.91.91.81.92.0-1.91.91.92.01.91.81.81.41.5
Patch foraging indifference point 0 sec0.40.81.41.00.91.20.60.90.91.10.80.90.80.60.80.90.81.00.9-1.01.01.10.91.00.70.70.80.6
Patch foraging indifference point AUC0.81.14.10.40.7-0.22.0-0.4-0.4-0.7-0.6-0.7-0.71.8-1.0-0.8-1.1-1.1-1.11.2-1.2-1.2-1.0-1.1-0.8-1.4-1.0-1.7
Delay disc. indifference point, 0s delay1.11.26.41.71.91.32.51.11.11.00.90.80.82.50.30.80.50.50.6-0.50.50.50.60.50.60.20.7-0.3
Delay disc. indifference point, 16s delay0.20.20.70.20.3-0.10.6-0.2-0.2-0.3-0.3-0.3-0.30.8-0.3-0.4-0.4-0.5-0.40.6-0.6-0.6-0.5-0.6-0.3-0.6-0.3-0.7
Delay disc. indifference point, 2s delay2.62.97.1-0.20.4-0.62.2-1.2-1.2-1.1-1.5-1.6-1.62.3-1.8-1.5-1.9-1.8-1.81.8-1.8-1.8-1.9-1.8-1.9-2.3-1.2-2.7
Delay disc. indifference point, 24s delay0.50.61.20.80.70.90.10.80.80.80.80.80.80.31.10.71.00.80.9-0.80.80.80.80.80.60.60.80.7
Delay disc. indifference point, 4s delay1.11.12.2-0.3-0.1-0.70.9-0.8-0.8-0.9-0.9-1.0-1.00.9-1.1-1.0-1.2-1.2-1.31.3-1.3-1.3-1.2-1.3-1.0-1.3-1.2-1.5
Delay disc. indifference point, 8s delay0.81.01.5-0.9-0.7-0.8-0.1-1.1-1.1-0.9-1.1-1.1-1.1-0.1-0.8-1.1-1.0-1.0-1.11.0-1.0-1.0-1.1-1.0-1.2-1.2-1.2-1.1
Indifference point function ln k1.93.44.61.41.21.80.41.81.82.01.91.91.90.11.82.02.12.12.0-2.12.12.11.92.11.72.11.52.1
Indifference point function log k1.93.44.61.41.21.80.41.81.82.01.91.91.90.11.82.02.12.12.0-2.12.12.11.92.11.72.11.52.1
Patch foraging total patch changes 0 sec0.20.40.70.60.50.80.20.60.60.80.50.60.50.20.50.60.60.70.6-0.70.70.80.60.80.50.50.60.4
Patch foraging total patch changes 12 sec0.30.42.80.91.00.71.70.40.40.40.20.20.11.6-0.20.2-0.10.1-0.0-0.00.00.10.00.1-0.0-0.30.1-0.6
Patch foraging total patch changes 18 sec0.91.43.1-0.5-0.0-0.61.0-1.1-1.1-0.9-1.3-1.3-1.30.9-1.5-1.2-1.4-1.3-1.31.3-1.3-1.2-1.3-1.3-1.4-1.4-0.8-1.8
Patch foraging total patch changes 24 sec0.10.20.7-0.00.40.20.7-0.4-0.4-0.1-0.5-0.5-0.50.7-0.8-0.3-0.5-0.3-0.40.3-0.3-0.3-0.4-0.3-0.7-0.50.2-0.7
Patch foraging total patch changes 6 sec0.10.21.20.60.40.20.80.10.0-0.1-0.1-0.1-0.21.1-0.1-0.2-0.4-0.4-0.50.4-0.4-0.4-0.3-0.4-0.1-0.7-0.5-0.9
Patch foraging time to switch 0 sec0.20.30.8-0.8-0.9-0.8-0.7-0.7-0.7-0.6-0.7-0.6-0.6-0.5-0.5-0.6-0.5-0.5-0.50.4-0.4-0.5-0.5-0.6-0.6-0.4-0.3-0.3
Patch foraging water rate 0 sec0.51.11.60.90.91.10.51.11.11.11.11.11.1-0.01.01.11.11.21.0-1.11.11.21.01.30.91.20.51.1
Patch foraging water rate 12 sec1.53.24.41.71.72.10.91.91.92.11.91.91.80.51.81.91.92.01.8-2.02.02.01.82.01.51.81.21.7
Patch foraging water rate 18 sec3.14.76.71.71.32.10.12.12.22.32.32.32.3-0.12.42.32.32.52.4-2.52.52.52.42.62.12.51.72.5
Patch foraging water rate 24 sec0.81.22.00.70.30.9-0.61.01.01.01.21.21.1-0.81.21.11.01.21.1-1.21.21.31.21.31.31.40.51.4
Patch foraging water rate 6 sec0.50.71.00.70.60.80.00.90.90.91.01.01.0-0.11.00.91.00.90.9-0.90.90.90.90.90.91.00.41.0
Seeking ratio, delayed vs. immediate footshock0.60.81.5-1.0-1.2-1.2-0.6-0.9-0.9-1.1-0.9-0.9-0.8-0.5-0.8-0.9-0.9-0.9-0.70.9-0.9-0.9-0.9-0.9-0.8-0.7-0.7-0.6
Distance traveled before self-admin1.11.51.9-1.2-1.1-1.3-0.2-1.3-1.3-1.2-1.3-1.3-1.3-0.3-1.4-1.3-1.3-1.3-1.31.2-1.2-1.2-1.3-1.3-1.3-1.2-1.3-1.2
Distance traveled after self-admin0.10.10.7-0.5-0.6-0.7-0.8-0.3-0.3-0.4-0.2-0.2-0.1-0.6-0.2-0.2-0.1-0.2-0.10.3-0.3-0.3-0.2-0.3-0.10.00.10.1
Extensor digitorum longus weight0.41.72.41.21.01.20.51.31.31.41.41.41.40.21.41.41.41.41.4-1.41.41.41.41.51.31.51.31.3
Bone: elastic displacement0.60.71.2-0.5-0.9-0.9-1.0-0.7-0.7-1.1-0.7-0.7-0.8-0.7-0.5-0.8-1.0-0.8-1.01.1-1.1-0.8-0.9-0.7-0.4-0.9-1.0-0.8
Bone: elastic work0.20.20.50.70.60.50.60.60.60.30.50.50.40.50.60.50.30.40.2-0.20.20.40.40.50.50.30.20.1
Bone: endosteal estimation0.30.73.51.21.40.91.90.90.80.80.70.70.71.60.50.70.50.40.6-0.40.40.40.60.40.70.40.70.0
Bone: endosteal perimeter1.32.716.52.43.01.93.91.51.41.41.01.01.04.10.51.10.60.60.7-0.50.50.40.60.60.70.31.4-0.6
Epididymis fat weight2.37.913.63.43.73.42.93.03.03.12.72.82.83.12.52.92.72.62.5-2.62.62.62.62.52.32.33.31.7
Delta time in closed arm before/after self-admin0.00.00.20.30.10.30.50.10.10.30.00.1-0.00.40.30.0-0.10.1-0.1-0.20.20.20.10.2-0.1-0.1-0.3-0.2
Delta time in open arm before/after self-admin0.00.00.1-0.10.0-0.10.0-0.1-0.1-0.2-0.1-0.1-0.0-0.1-0.3-0.1-0.0-0.10.00.2-0.2-0.2-0.1-0.2-0.1-0.1-0.1-0.0
Diff in mean of infusions in LGA sessions1.51.94.11.91.91.72.01.51.51.51.31.31.32.01.21.31.01.11.0-1.11.11.11.11.21.21.01.10.4
Delay discount exponential model param0.60.61.40.30.10.4-0.70.60.70.60.80.80.8-0.70.70.80.80.90.9-0.90.90.90.90.91.01.10.91.2
Extinction: sum of active levers before priming0.30.30.90.10.2-0.40.9-0.3-0.3-0.4-0.3-0.4-0.40.9-0.3-0.5-0.6-0.7-0.60.7-0.7-0.7-0.6-0.7-0.2-0.6-0.4-0.9
Active lever presses in extinction session 62.22.22.81.61.31.40.91.71.71.51.71.61.60.81.61.61.51.51.5-1.41.41.41.51.41.61.51.31.3
Bone: final force0.10.11.20.20.50.31.1-0.0-0.00.2-0.1-0.1-0.10.8-0.3-0.00.00.0-0.10.0-0.00.0-0.10.1-0.5-0.20.1-0.3
Bone: final moment0.10.10.6-0.10.20.10.7-0.3-0.2-0.1-0.3-0.3-0.30.5-0.4-0.2-0.3-0.2-0.40.3-0.3-0.1-0.4-0.1-0.6-0.4-0.2-0.5
Food consumed during 24 hour testing period2.23.13.61.71.51.80.81.91.91.91.91.91.81.11.81.91.81.91.9-1.91.91.91.91.91.71.81.61.6
Glucose0.10.20.60.10.1-0.10.7-0.3-0.3-0.2-0.4-0.4-0.40.6-0.5-0.4-0.6-0.5-0.60.4-0.4-0.5-0.6-0.4-0.4-0.6-0.6-0.8
Heart weight0.40.61.30.30.30.7-0.40.60.60.80.70.80.7-0.60.60.80.81.00.7-1.01.01.10.71.10.70.90.81.1
Delay discount hyperbolic model param0.91.02.10.40.10.6-0.80.80.90.81.01.01.0-0.81.01.01.11.11.1-1.11.11.11.11.11.21.31.01.4
Intermittent access intake day 1-15 change0.61.11.71.31.11.21.01.21.21.21.11.11.10.81.11.10.91.11.0-1.11.11.11.11.11.01.00.70.7
Intermittent access intake escalation0.61.31.91.41.21.31.11.21.21.21.21.21.10.91.21.11.01.11.0-1.11.11.11.11.21.11.00.80.7
Intermittent access intake escalation 22.12.44.52.12.01.81.91.71.71.71.61.61.52.01.41.51.31.41.3-1.31.31.31.41.41.41.21.20.7
Intermitt. access day 1 inactive lever presses0.20.91.91.31.41.11.31.11.11.01.00.90.91.20.90.90.80.70.7-0.70.70.70.70.70.80.70.70.4
Intermitt. access day 15 inactive lever presses1.63.34.81.41.01.5-0.31.91.91.72.02.02.0-0.42.11.92.12.02.0-2.02.02.02.02.02.02.21.42.2
Intermitt. access escalation Index0.30.41.0-0.9-0.9-0.8-0.9-0.7-0.7-0.7-0.6-0.6-0.6-1.0-0.6-0.6-0.5-0.5-0.30.5-0.5-0.5-0.3-0.5-0.5-0.3-0.4-0.2
Intermittent access day 1 total infusions0.00.00.2-0.1-0.2-0.1-0.40.10.1-0.10.10.10.1-0.40.20.10.20.20.2-0.10.10.20.10.10.10.2-0.00.3
Intermittent access day 15 total infusions0.20.30.50.50.40.50.30.60.60.50.60.60.50.10.70.50.50.50.6-0.40.40.60.60.50.50.60.10.5
Intermittent access terminal intake (last 3 days)1.31.72.61.61.51.51.31.51.51.31.41.41.41.21.61.31.21.31.3-1.21.21.31.31.31.21.20.80.9
Intermittent access total infusions0.20.20.40.60.50.50.50.60.50.40.50.50.50.40.60.50.50.40.5-0.30.30.40.40.40.40.50.20.3
Intermittent access day 1 locomotion0.00.00.20.10.20.10.40.00.0-0.00.0-0.00.00.3-0.1-0.0-0.0-0.00.10.1-0.1-0.0-0.0-0.1-0.10.0-0.1-0.1
Intermittent access day 15 total locomotion0.71.22.11.41.41.31.31.31.31.21.21.21.11.21.11.10.91.01.0-0.90.91.01.01.01.10.90.70.6
Intermittent access total locomotion0.70.91.11.00.91.00.61.01.01.01.01.01.00.51.01.00.91.01.0-0.90.91.01.01.00.91.00.60.8
Intermittent access standard deviation0.20.50.90.40.10.5-0.50.60.60.60.70.70.7-0.50.90.70.70.80.7-0.80.80.90.70.90.80.90.41.0
Left kidney weight4.721.828.65.44.74.92.95.35.34.95.25.15.13.15.24.94.64.64.5-4.64.54.54.84.55.14.54.13.8
Right kidney weight7.232.643.26.35.55.83.16.46.45.96.46.26.23.46.66.05.75.65.7-5.65.65.55.95.66.25.65.24.8
Cocaine induced anxiety0.71.02.40.80.50.7-0.21.11.10.91.21.11.2-0.21.51.01.21.01.2-1.11.11.01.11.01.21.10.71.2
Post-drug Anxiety1.21.32.80.80.40.7-0.51.11.11.01.31.31.3-0.41.71.11.31.21.2-1.21.21.11.21.11.31.40.81.4
Baseline Anxiety0.40.40.9-0.8-0.8-0.6-0.6-0.8-0.8-0.6-0.7-0.7-0.7-0.6-0.7-0.7-0.7-0.6-0.90.5-0.5-0.5-0.7-0.5-0.6-0.5-0.6-0.5
Tail length0.51.93.0-1.4-1.5-1.7-1.2-1.4-1.4-1.5-1.3-1.4-1.3-1.2-1.2-1.4-1.4-1.5-1.41.4-1.4-1.6-1.3-1.6-1.0-1.2-1.3-1.1
Length with tail0.00.10.40.00.1-0.30.3-0.1-0.1-0.3-0.1-0.2-0.20.30.3-0.3-0.3-0.5-0.40.5-0.5-0.6-0.3-0.5-0.1-0.3-0.3-0.4
Length without tail0.30.93.71.41.61.01.91.11.00.70.90.80.81.91.20.70.50.40.5-0.30.30.20.50.30.70.30.4-0.1
Times rat made contact with spout1.11.23.1-0.1-0.60.2-1.70.70.70.60.91.00.9-1.71.50.81.11.21.2-1.11.11.21.21.21.01.40.21.8
Lifetime Intake0.20.30.60.60.50.50.40.60.60.50.60.60.60.30.80.60.60.50.7-0.40.40.50.50.50.50.60.20.5
Liver weight, left0.30.53.01.11.30.91.70.70.70.70.60.50.51.50.30.50.30.30.3-0.30.40.30.40.30.40.00.0-0.2
Liver weight, right0.10.20.80.00.1-0.20.8-0.3-0.3-0.3-0.3-0.4-0.40.6-0.3-0.4-0.6-0.5-0.50.5-0.4-0.5-0.5-0.5-0.5-0.5-0.9-0.7
Locomotor activity0.40.63.61.31.31.01.90.80.80.70.60.60.51.70.20.60.30.40.3-0.30.30.40.40.50.50.10.3-0.3
Locomotor testing distance0.61.02.0-0.9-0.9-0.9-0.1-1.1-1.0-1.1-1.1-1.0-1.1-0.3-1.4-1.0-1.1-1.0-1.21.1-1.1-0.9-1.1-0.9-1.0-1.1-1.2-1.0
Locomotor testing rearing0.51.17.40.71.00.32.7-0.2-0.2-0.2-0.5-0.5-0.62.4-0.8-0.5-0.9-0.8-0.90.8-0.8-0.8-0.9-0.8-0.9-1.2-0.6-1.7
Locomotion in novel chamber1.21.63.70.4-0.10.5-1.01.01.01.01.31.31.3-1.21.51.31.31.41.5-1.41.41.41.31.41.11.81.11.9
Locomotion in novel chamber post-restriction0.10.10.50.20.2-0.10.7-0.1-0.1-0.2-0.2-0.2-0.20.7-0.5-0.2-0.3-0.3-0.30.3-0.3-0.3-0.5-0.3-0.5-0.30.0-0.6
Fecal boli incidents, locomotor time 10.40.50.7-0.9-0.9-0.8-0.7-0.8-0.8-0.7-0.8-0.8-0.8-0.6-0.7-0.8-0.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.7-0.5-0.6
Change in fecal boli incidents, locomotor task0.40.41.00.70.50.70.30.70.70.70.70.70.70.31.00.60.70.70.7-0.70.70.70.70.70.60.50.40.5
Time >=10cm from walls, locomotor time 10.40.40.90.90.90.70.70.80.80.60.70.60.60.90.50.60.50.50.5-0.40.40.40.50.40.70.30.70.2
Bouts of movement, locomotor time 10.60.71.10.4-0.00.6-0.50.60.60.90.70.80.7-0.30.90.80.91.01.0-1.01.01.10.91.10.71.01.00.9
Total resting periods, locomotor time 10.20.20.7-0.0-0.40.1-0.80.20.20.40.20.30.3-0.60.60.30.50.50.5-0.60.60.60.50.60.30.50.60.6
Rest time, locomotor task time 10.30.33.2-0.8-1.1-0.6-1.8-0.4-0.4-0.3-0.3-0.2-0.2-1.50.0-0.20.10.10.1-0.10.10.10.00.1-0.10.20.20.5
Distance moved, locomotor task time 10.30.42.41.01.10.81.50.70.70.60.60.50.51.30.10.50.20.40.4-0.40.40.40.40.40.40.20.3-0.1
Vertical activity count, locomotor time 10.71.65.11.81.91.62.31.41.41.41.21.21.22.00.61.21.01.01.0-1.01.01.01.01.00.80.70.90.3
Time >=10cm from walls, locomotor time 21.62.43.82.01.91.81.41.81.81.61.71.61.61.51.61.61.61.41.4-1.41.41.41.51.41.51.21.41.0
Bouts of movement, locomotor time 20.20.30.5-0.7-0.7-0.7-0.1-0.6-0.6-0.6-0.6-0.6-0.6-0.3-0.5-0.6-0.5-0.6-0.60.6-0.6-0.6-0.6-0.6-0.7-0.4-0.6-0.4
Total resting periods, locomotor time 20.20.40.6-0.7-0.6-0.7-0.0-0.7-0.7-0.6-0.7-0.7-0.6-0.2-0.7-0.7-0.5-0.6-0.60.6-0.6-0.6-0.7-0.6-0.8-0.4-0.6-0.5
Rest time, locomotor task time 20.91.23.1-1.6-1.6-1.3-1.8-1.3-1.2-1.2-1.1-1.1-1.1-1.6-0.8-1.0-0.8-0.8-0.90.8-0.8-0.8-0.9-0.8-0.8-0.6-0.5-0.3
Distance moved, locomotor task time 22.12.54.82.12.11.92.21.81.81.81.61.61.62.01.11.61.41.41.4-1.41.41.41.41.41.31.11.10.7
Vertical activity count, locomotor time 22.12.95.12.22.22.12.21.91.92.01.71.71.72.01.01.71.71.51.6-1.61.61.61.51.61.21.21.20.8
Light reinforcement 10.41.03.01.41.61.31.51.11.11.01.00.90.91.70.50.90.60.70.6-0.70.70.70.70.51.00.50.80.2
Light reinforcement 22.53.88.12.72.82.32.72.32.22.02.11.92.02.81.81.91.51.51.5-1.51.51.41.71.31.81.31.50.7
Bone: marrow area0.20.53.01.01.20.71.70.70.70.60.60.50.51.50.40.50.30.30.4-0.30.30.20.40.20.50.30.6-0.1
Bone: maximum diameter1.63.16.72.22.62.12.51.81.81.81.61.71.72.41.21.81.61.51.5-1.41.41.41.51.61.31.32.10.8
Bone: maximum force0.00.10.70.30.50.30.90.20.20.20.10.10.10.60.10.10.10.10.1-0.10.10.10.10.2-0.1-0.00.1-0.1
Bone: maximum moment0.00.00.20.10.10.00.4-0.1-0.1-0.1-0.1-0.1-0.20.2-0.1-0.1-0.2-0.1-0.20.2-0.2-0.1-0.10.0-0.2-0.2-0.3-0.3
Mean time between licks in bursts1.53.65.7-2.4-2.3-2.3-2.0-2.1-2.1-2.2-2.0-2.0-1.9-1.9-1.9-1.9-1.7-1.8-1.71.8-1.8-1.9-1.7-1.7-1.7-1.6-1.6-1.1
Mean num. licks in bursts0.10.20.70.0-0.30.3-0.40.20.30.40.30.40.3-0.60.70.30.40.60.4-0.60.60.70.40.80.30.6-0.20.7
Cd content in liver0.40.40.8-0.4-0.2-0.40.2-0.7-0.7-0.5-0.7-0.7-0.80.2-0.7-0.7-0.7-0.8-0.80.7-0.7-0.7-0.7-0.7-0.6-0.8-0.6-0.9
Co content in liver0.20.20.91.00.80.60.30.60.60.30.50.50.40.80.40.40.20.20.2-0.00.00.10.40.20.9-0.10.4-0.1
Cu content in liver0.70.94.7-1.7-1.6-1.1-2.1-1.0-1.0-0.7-0.8-0.7-0.6-2.2-0.7-0.6-0.2-0.3-0.10.2-0.2-0.3-0.4-0.3-0.70.1-0.40.5
Fe content in liver0.10.20.60.10.30.00.8-0.2-0.2-0.2-0.3-0.3-0.30.6-0.4-0.3-0.4-0.4-0.30.4-0.4-0.4-0.4-0.4-0.6-0.5-0.4-0.7
K content in liver0.20.20.4-0.4-0.3-0.5-0.5-0.3-0.4-0.5-0.4-0.4-0.3-0.0-0.6-0.3-0.4-0.5-0.30.5-0.5-0.5-0.3-0.5-0.1-0.40.2-0.3
Mg content in liver1.01.11.7-0.6-0.7-1.0-0.3-0.9-0.9-1.1-1.0-1.0-1.00.2-1.2-1.0-1.3-1.2-1.11.2-1.2-1.2-1.1-1.3-0.7-1.3-0.9-1.2
Mn content in liver0.10.10.20.20.2-0.2-0.00.00.0-0.3-0.0-0.1-0.00.4-0.3-0.0-0.1-0.4-0.20.4-0.4-0.40.0-0.50.3-0.30.3-0.3
Na content in liver3.84.06.9-1.7-0.8-1.60.4-2.1-2.1-1.9-2.2-2.2-2.10.4-2.6-2.1-2.0-2.2-2.12.2-2.2-2.2-2.3-2.3-2.4-2.1-1.4-2.3
Rb content in liver0.10.10.60.40.40.20.50.10.1-0.1-0.0-0.1-0.10.8-0.2-0.1-0.3-0.2-0.10.3-0.3-0.2-0.1-0.2-0.1-0.4-0.1-0.5
Se content in liver0.20.20.70.3-0.00.1-0.50.50.50.30.50.50.5-0.30.60.50.50.40.4-0.40.40.40.50.40.80.60.50.6
Sr content in liver1.51.32.5-1.6-1.5-1.3-1.4-1.3-1.3-1.2-1.2-1.2-1.2-1.4-1.2-1.2-1.0-1.0-1.00.9-0.9-1.0-1.1-1.0-1.1-0.8-1.0-0.5
Zn content in liver0.91.02.9-1.4-1.6-1.3-1.7-1.0-1.0-1.0-0.9-0.9-0.9-1.5-0.6-0.9-0.9-0.8-0.80.7-0.7-0.8-0.8-0.9-0.5-0.6-1.0-0.2
Bone: minimum diameter0.71.24.31.41.81.52.01.01.01.20.80.80.82.10.41.00.80.80.8-0.80.80.80.80.90.50.61.20.2
Time in familiar zone, hab. session 10.30.31.4-0.1-0.6-0.2-1.20.30.30.00.40.40.4-1.20.70.30.40.40.5-0.30.30.40.50.40.70.5-0.10.8
Time in novel zone, hab. session 10.50.51.2-0.30.0-0.30.5-0.7-0.7-0.5-0.8-0.8-0.80.6-1.1-0.7-0.9-0.8-1.00.7-0.7-0.7-0.9-0.8-0.8-0.9-0.3-1.1
Total zone transitions, hab. session 12.83.95.5-1.8-1.5-2.10.0-2.0-2.0-2.1-2.0-2.1-2.0-0.5-1.7-2.1-2.1-2.2-2.02.2-2.2-2.2-2.1-2.1-2.1-2.1-2.3-2.0
Total locomotion distance, hab. session 10.40.51.4-0.0-0.0-0.51.0-0.4-0.4-0.7-0.4-0.5-0.60.6-0.1-0.7-0.9-0.9-0.80.9-0.9-0.9-0.8-0.8-0.5-0.8-1.2-1.0
Locomotion velocity, hab. session 10.50.61.5-0.10.1-0.51.1-0.5-0.5-0.7-0.5-0.6-0.70.8-0.3-0.7-1.0-0.9-0.91.0-1.0-1.0-0.9-0.9-0.7-1.0-1.2-1.2
Time in familiar zone, hab. session 21.71.83.00.80.51.1-0.71.21.31.31.31.41.4-0.51.31.41.51.51.5-1.51.51.61.51.61.51.61.51.7
Time in novel zone, hab. session 22.12.22.9-1.2-1.2-1.4-0.5-1.5-1.5-1.5-1.5-1.6-1.6-0.4-1.5-1.6-1.7-1.6-1.71.6-1.6-1.6-1.6-1.6-1.4-1.7-1.5-1.6
Total zone transitions, hab. session 20.10.10.20.10.00.00.30.20.20.10.30.30.3-0.10.50.20.20.20.4-0.20.20.20.30.30.20.3-0.20.3
Total locomotion distance, hab. session 20.60.81.91.20.90.80.81.11.10.91.11.01.00.61.40.90.80.80.8-0.80.80.70.90.81.10.80.30.6
Locomotion velocity, hab. session 20.60.81.81.21.00.81.01.11.10.81.11.01.00.71.30.90.70.70.8-0.70.70.70.80.71.00.70.20.5
Novel to familiar place preference ratio0.40.52.8-1.0-1.1-1.0-1.7-0.6-0.6-0.7-0.5-0.5-0.4-1.3-0.7-0.4-0.3-0.4-0.30.5-0.5-0.5-0.2-0.4-0.1-0.20.10.1
Novelty place preference0.40.43.3-0.8-1.0-0.9-1.8-0.4-0.4-0.6-0.3-0.3-0.3-1.3-0.4-0.3-0.2-0.3-0.20.3-0.3-0.3-0.1-0.30.2-0.10.20.3
Time in novel zone, NPP test0.50.54.4-1.0-1.3-1.0-2.1-0.6-0.6-0.7-0.4-0.4-0.3-1.6-0.5-0.4-0.2-0.4-0.30.4-0.4-0.4-0.1-0.40.1-0.10.10.3
Total zone transitions, NPP test0.81.12.4-1.0-1.1-1.30.1-1.1-1.1-1.2-1.0-1.1-1.1-0.5-0.7-1.1-1.1-1.1-1.01.2-1.2-1.1-1.1-1.0-1.1-1.0-1.5-0.9
Total locomotion distance, NPP test0.10.10.80.30.2-0.10.90.00.0-0.2-0.0-0.1-0.10.70.1-0.2-0.4-0.3-0.30.4-0.4-0.4-0.3-0.3-0.0-0.3-0.6-0.5
Locomotion velocity, NPP test0.10.11.00.40.30.01.00.20.2-0.10.10.00.00.80.3-0.1-0.2-0.2-0.20.3-0.3-0.3-0.2-0.20.0-0.2-0.5-0.4
Intraocular pressure0.30.43.50.81.20.91.90.30.30.60.10.20.11.7-0.40.30.20.2-0.0-0.20.30.3-0.10.3-0.1-0.20.4-0.5
Delta distance traveled before/after self-admin3.23.34.91.40.91.4-0.71.81.81.61.92.02.0-0.42.02.02.22.02.1-1.91.91.91.92.02.02.22.12.2
Delta ambulatory time before/after self-admin1.72.13.31.00.61.1-0.81.41.41.31.51.61.6-0.41.61.51.71.61.7-1.51.51.51.51.61.51.71.71.8
Parametrial fat weight0.40.93.21.11.51.21.81.01.01.00.90.90.91.30.60.90.90.90.9-0.70.70.80.70.80.40.70.70.5
Pavlov. Cond. lever latency1.82.33.7-1.9-1.9-1.8-1.6-1.7-1.7-1.7-1.5-1.5-1.5-1.8-1.2-1.6-1.5-1.4-1.41.4-1.4-1.4-1.4-1.4-1.3-1.1-1.7-0.9
Pavlov. Cond. magazine entry latency0.00.00.3-0.10.20.2-0.1-0.2-0.20.1-0.3-0.2-0.20.3-0.6-0.1-0.10.1-0.0-0.00.00.1-0.20.2-0.4-0.20.4-0.2
Pavlov. Cond. change in total contacts0.40.42.50.71.10.91.40.30.40.60.10.20.21.6-0.40.40.30.40.3-0.30.30.40.20.5-0.1-0.11.1-0.2
Pavlov. Cond. index score0.20.30.80.50.80.70.70.40.40.60.30.40.40.9-0.00.50.40.50.5-0.50.50.50.30.60.10.20.90.2
Pavlov. Cond. latency score0.40.61.30.81.11.00.90.70.70.90.50.60.61.10.20.70.70.70.7-0.70.70.70.60.80.40.41.10.3
Pavlov. Cond. lever contacts1.72.03.41.71.81.61.41.51.51.61.41.41.41.71.01.51.41.31.4-1.31.31.31.31.41.21.01.80.8
Pavlov. Cond. magazine entry number0.10.10.50.1-0.1-0.2-0.20.30.3-0.00.40.30.4-0.50.70.20.20.00.2-0.10.1-0.00.3-0.10.60.4-0.30.4
Pavlov. Cond. intertrial magazine entries1.41.73.41.71.71.51.81.51.41.41.31.31.31.61.21.31.21.11.2-1.11.11.11.20.91.11.11.20.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.80.40.70.50.70.20.20.40.10.20.20.9-0.20.30.30.30.3-0.30.30.30.10.4-0.10.00.7-0.0
Pavlov. Cond. response bias0.40.51.00.90.90.90.60.70.70.80.60.70.61.00.30.70.70.70.7-0.70.70.80.60.90.50.41.00.4
Pavlov. Cond. lever latency1.72.42.9-1.5-1.6-1.7-1.3-1.6-1.6-1.6-1.5-1.6-1.6-1.1-1.5-1.6-1.7-1.6-1.61.5-1.5-1.6-1.6-1.6-1.3-1.5-1.7-1.3
Pavlov. Cond. magazine entry latency1.01.21.71.01.31.31.21.11.11.21.01.01.10.91.01.11.21.11.2-1.11.11.11.01.00.71.11.30.9
Pavlov. Cond. change in total contacts0.40.64.70.81.41.02.20.50.50.70.40.40.41.60.30.40.50.40.4-0.30.30.40.30.4-0.10.20.6-0.1
Pavlov. Cond. index score1.11.52.41.31.51.41.61.31.31.31.21.21.21.21.31.21.31.21.2-1.11.11.21.11.20.91.11.30.9
Pavlov. Cond. latency score1.82.43.11.61.81.81.51.61.61.61.61.61.61.31.61.61.71.61.6-1.51.51.51.51.51.31.51.61.3
Pavlov. Cond. lever contacts1.82.52.91.61.71.71.41.61.61.61.61.61.61.21.61.61.71.61.6-1.51.51.61.61.61.41.61.71.3
Pavlov. Cond. magazine entry number1.41.72.6-1.3-1.6-1.6-1.5-1.3-1.3-1.5-1.2-1.3-1.3-1.2-1.3-1.3-1.4-1.3-1.31.3-1.3-1.3-1.2-1.2-0.9-1.2-1.4-1.0
Pavlov. Cond. intertrial magazine entries0.20.32.2-0.5-0.9-0.7-1.5-0.3-0.3-0.6-0.1-0.2-0.2-1.20.1-0.3-0.4-0.4-0.40.4-0.4-0.4-0.2-0.30.2-0.1-0.70.0
Pavlov. Cond. lever-magazine prob. diff.1.21.72.51.31.61.51.51.31.31.31.31.31.31.21.31.31.41.31.3-1.21.21.21.21.21.01.21.31.0
Pavlov. Cond. response bias0.70.91.61.01.31.11.21.01.01.00.90.90.91.10.91.01.00.91.0-0.90.90.90.90.90.70.91.20.7
Time in closed arm before self-admin1.01.33.1-0.20.4-0.61.5-0.8-0.8-0.9-1.0-1.1-0.91.4-1.8-0.9-1.0-1.3-1.11.4-1.4-1.4-1.4-1.4-1.1-1.4-0.3-1.6
Time in closed arm after self-admin0.50.64.40.81.10.52.10.10.10.2-0.2-0.2-0.22.1-0.5-0.1-0.4-0.3-0.40.3-0.3-0.3-0.4-0.3-0.4-0.7-0.1-1.1
Time in open arm before self-admin0.10.11.2-0.5-0.7-0.4-1.1-0.2-0.2-0.2-0.1-0.1-0.1-0.90.4-0.2-0.10.0-0.0-0.00.00.00.10.10.10.2-0.30.3
Time in open arm after self-admin0.00.00.1-0.1-0.1-0.1-0.40.10.00.00.10.10.1-0.30.10.10.10.10.2-0.10.10.10.20.00.10.30.10.3
Bone: periosteal estimation0.71.57.51.72.11.62.71.21.21.21.01.00.92.40.61.00.80.80.8-0.70.70.80.80.90.60.61.10.1
Bone: periosteal perimeter1.72.811.42.42.92.13.41.71.71.71.31.31.33.30.91.41.11.11.1-1.11.11.01.01.20.90.81.60.1
Bone: post-yield work0.60.91.9-1.4-1.2-1.0-0.8-1.2-1.2-0.8-1.1-1.1-1.1-1.2-0.8-1.1-0.9-0.8-0.70.6-0.6-0.7-0.8-0.8-1.1-0.7-1.1-0.5
Progressive ratio test 1 active lever presses0.10.21.2-0.5-0.7-0.4-1.0-0.1-0.1-0.20.10.10.1-1.10.40.00.30.10.3-0.00.00.10.10.10.10.4-0.10.6
Progressive ratio test 1 breakpoint0.10.21.2-0.5-0.7-0.5-1.0-0.2-0.2-0.3-0.0-0.00.0-1.10.3-0.10.20.00.30.1-0.10.00.1-0.00.10.3-0.10.5
Progressive ratio test 1 inactive lever presses0.10.10.40.50.40.40.40.40.40.30.40.40.40.40.60.30.40.30.2-0.30.30.30.20.30.30.30.20.2
Progressive ratio test 2 active lever presses0.80.91.51.10.90.90.61.11.10.91.11.11.10.51.21.01.01.01.0-0.90.90.91.00.91.11.00.80.8
Progressive ratio test 2 breakpoint0.60.71.10.90.80.80.50.90.90.70.90.90.90.51.00.90.80.80.9-0.70.70.80.80.80.90.90.70.7
Progressive ratio test 2 inactive lever presses0.71.11.81.31.21.11.11.21.21.01.21.21.10.91.31.10.91.01.0-0.90.91.01.01.01.11.00.70.7
Incentive Sensitization - Responses1.11.63.01.71.71.51.61.41.41.31.31.31.31.61.21.21.11.11.1-1.01.01.01.11.01.21.01.00.6
Incentive Sensitization - Breakpoint1.11.42.71.71.71.41.51.41.41.21.31.21.21.51.11.21.01.01.0-1.01.01.01.11.01.10.91.00.5
Sum of active levers in priming session hrs 5-60.10.10.40.40.50.30.30.30.30.30.30.30.30.50.30.30.20.20.2-0.10.10.10.30.10.50.20.60.0
Progressive ratio0.20.30.70.50.10.2-0.20.60.60.40.60.60.60.10.80.50.60.60.6-0.50.50.50.60.50.80.60.70.6
Food seeking constrained by brief footshock2.73.34.72.21.81.81.42.12.11.82.12.02.01.22.21.91.91.71.8-1.71.71.71.91.71.91.61.31.4
Seeking ratio, punishment vs. effort0.10.21.70.60.80.61.30.30.30.30.20.10.10.9-0.00.20.10.00.1-0.10.10.10.00.1-0.1-0.1-0.3-0.3
Retroperitoneal fat weight2.611.216.94.04.13.93.33.73.73.63.53.53.53.13.13.53.23.23.2-3.13.13.13.33.03.12.93.22.3
Reaction time number correct0.50.91.3-1.0-0.8-1.1-0.5-1.0-1.0-1.1-1.0-1.0-0.9-0.2-0.9-1.0-0.8-1.0-0.91.1-1.1-1.1-1.0-1.1-1.0-0.8-0.9-0.8
Reaction time mean minus median0.10.20.40.50.50.50.70.40.40.40.40.30.30.60.40.30.20.30.3-0.30.30.30.30.20.40.10.40.1
Reaction time mean minus median AUC0.10.10.30.50.30.30.30.50.40.30.50.40.40.30.50.40.30.30.4-0.40.40.30.40.30.60.30.30.3
Reaction time num false alarms0.00.00.1-0.2-0.2-0.0-0.2-0.2-0.20.0-0.3-0.3-0.20.1-0.3-0.2-0.2-0.1-0.2-0.00.0-0.0-0.3-0.2-0.2-0.10.4-0.2
Reaction time num false alarms AUC0.00.00.3-0.2-0.30.0-0.6-0.1-0.10.2-0.1-0.1-0.0-0.3-0.00.00.00.20.1-0.30.30.30.00.10.00.20.50.2
Reaction time trials correct on left0.50.91.3-1.0-0.8-1.1-0.5-1.0-1.0-1.1-1.0-1.0-0.9-0.2-0.9-1.0-0.8-1.0-0.91.1-1.1-1.1-1.0-1.1-1.0-0.8-0.9-0.8
Reaction time trials on left0.50.91.3-1.0-0.9-1.1-0.6-1.0-1.0-1.1-1.0-1.0-0.9-0.3-0.9-1.0-0.8-1.0-0.91.1-1.1-1.1-1.0-1.1-1.0-0.8-0.9-0.8
Reaction time mean0.20.32.0-0.9-0.9-0.6-1.2-0.5-0.5-0.4-0.3-0.3-0.3-1.4-0.2-0.30.0-0.1-0.00.1-0.1-0.1-0.1-0.2-0.20.1-0.20.4
Reaction time mean AUC0.20.31.8-1.0-1.0-0.7-1.1-0.6-0.6-0.5-0.4-0.4-0.4-1.4-0.3-0.4-0.1-0.3-0.10.2-0.2-0.3-0.2-0.4-0.3-0.1-0.30.2
Median of all reaction times0.40.64.3-1.3-1.3-0.9-1.8-0.6-0.6-0.6-0.4-0.4-0.3-2.1-0.3-0.40.0-0.2-0.00.1-0.1-0.2-0.1-0.3-0.20.2-0.30.6
Reaction time omissions0.20.31.0-0.8-1.0-0.5-1.0-0.6-0.6-0.4-0.6-0.5-0.5-1.0-0.4-0.5-0.4-0.2-0.30.1-0.1-0.1-0.4-0.2-0.4-0.2-0.2-0.1
Reaction time false alarm rate0.10.20.70.30.20.6-0.00.30.30.70.20.30.30.00.20.40.30.60.4-0.70.70.60.40.50.30.40.80.3
Reaction time premature initiation rate3.44.79.43.03.02.82.92.42.42.52.12.12.03.11.52.11.81.91.8-2.02.01.91.81.81.81.42.00.7
Reaction time premature initiations1.01.85.81.92.01.72.11.41.41.51.21.21.22.40.81.21.01.01.0-1.01.01.00.90.90.90.71.10.2
Std. dev. reaction times0.10.20.40.20.10.40.10.40.40.50.40.40.4-0.10.50.40.50.50.6-0.60.60.60.50.50.40.50.40.6
Reaction time trials completed0.50.91.3-1.0-0.9-1.1-0.6-1.0-1.0-1.1-1.0-1.0-0.9-0.3-0.9-1.0-0.8-1.0-0.91.1-1.1-1.1-1.0-1.1-1.0-0.8-0.9-0.8
Reaction time trials AUC0.30.60.9-0.8-0.7-0.9-0.4-0.8-0.8-0.9-0.8-0.8-0.7-0.1-0.7-0.8-0.6-0.8-0.70.9-0.9-0.9-0.8-0.8-0.9-0.6-0.7-0.6
Run reversals in cocaine runway, females0.10.10.6-0.1-0.4-0.1-0.80.10.10.10.20.20.2-0.70.40.20.20.30.2-0.30.30.30.40.30.50.30.10.5
Run reversals in cocaine runway, males0.80.81.5-0.4-0.2-0.60.6-0.8-0.8-0.8-0.9-0.9-0.90.5-1.0-0.9-1.0-1.0-1.01.0-1.0-1.0-1.0-1.0-0.9-1.1-0.8-1.2
Latency to leave start box in cocaine runway1.71.93.01.10.81.10.21.51.51.31.61.61.60.11.71.51.71.51.5-1.51.51.51.51.51.51.61.01.6
Latency to leave start box in cocaine runway, F3.23.76.81.10.61.2-1.01.81.81.62.12.12.1-1.02.22.02.32.12.2-2.12.12.12.22.12.22.41.42.6
Latency to leave start box in cocaine runway, M0.30.32.50.50.80.41.60.10.10.1-0.0-0.1-0.11.4-0.1-0.1-0.2-0.2-0.20.2-0.2-0.2-0.3-0.2-0.3-0.4-0.2-0.7
Std. dev. time between licks in bursts0.81.03.41.61.61.21.81.21.20.91.11.00.91.71.20.90.60.60.7-0.60.60.50.80.70.90.50.40.2
Total sessions with >9 infusions0.20.30.70.30.10.3-0.20.50.50.40.60.60.6-0.40.80.50.70.60.7-0.50.50.60.50.60.50.70.30.8
Short access day 1 total inactive lever presses3.95.17.22.11.62.10.42.42.42.32.52.52.50.32.72.42.42.52.3-2.52.52.52.42.52.42.51.82.4
Short access day 10 total inactive lever presses3.78.912.33.53.33.42.33.33.33.33.23.23.12.32.93.12.92.93.0-3.03.02.93.12.92.82.72.52.1
Short access day 1 total infusions0.91.22.40.80.40.8-0.11.11.10.91.21.21.2-0.31.51.11.31.21.4-1.11.11.21.31.11.21.40.71.4
Short access day 10 total infusions0.81.11.81.00.70.90.31.11.11.01.21.21.20.21.41.11.21.11.2-1.01.01.11.11.11.11.20.81.1
Short access total infusions0.70.91.70.80.60.80.31.01.00.81.11.01.00.11.31.01.11.01.2-0.90.91.01.00.90.91.10.51.0
Short access day 1 locomotion0.91.11.90.80.50.8-0.01.11.10.91.21.21.2-0.31.31.11.31.21.2-1.11.11.11.11.11.21.40.81.3
Short access day 10 total locomotion0.71.41.71.10.91.20.61.21.21.31.21.21.20.41.21.21.21.31.3-1.31.31.31.31.31.11.30.91.1
Short access total locomotion0.60.71.10.80.70.80.50.90.90.90.90.90.90.30.90.90.90.91.0-0.90.91.00.90.90.81.00.60.8
One hour access (0.3 mA shock)1.01.12.41.51.51.11.51.31.21.01.21.11.11.51.11.00.90.81.0-0.80.80.81.00.71.00.80.60.4
Compulsive drug intake0.00.00.10.00.10.10.2-0.1-0.1-0.0-0.1-0.1-0.10.2-0.2-0.0-0.1-0.0-0.10.0-0.0-0.0-0.0-0.1-0.1-0.20.1-0.1
One hour access (shock baseline)0.50.71.71.21.10.91.31.01.00.80.90.80.81.11.00.80.70.60.8-0.60.60.60.70.60.70.70.40.3
Social response proportion0.20.20.8-0.10.2-0.00.7-0.3-0.3-0.1-0.4-0.4-0.40.8-0.8-0.3-0.3-0.3-0.30.3-0.3-0.3-0.4-0.2-0.9-0.5-0.1-0.6
Social responses0.10.21.30.10.50.11.2-0.1-0.1-0.0-0.3-0.2-0.21.0-0.6-0.1-0.2-0.2-0.30.2-0.2-0.2-0.3-0.2-0.7-0.40.1-0.5
Social time0.40.51.30.1-0.20.2-0.80.50.50.50.70.70.7-0.60.80.60.80.80.7-0.80.80.80.80.80.50.90.31.1
Soleus weight1.13.24.01.71.41.71.31.91.91.81.91.91.90.72.01.91.91.91.7-1.91.81.91.81.91.82.01.61.8
Bone: stiffness0.10.10.3-0.4-0.2-0.30.2-0.4-0.4-0.3-0.4-0.4-0.4-0.1-0.3-0.4-0.2-0.3-0.30.3-0.3-0.4-0.3-0.4-0.5-0.3-0.4-0.3
Tibialis anterior weight0.10.20.50.30.30.40.20.40.40.50.40.40.50.00.30.50.40.50.4-0.50.50.50.40.50.50.70.70.5
Time to tail flick, vehicle, before self-admin1.81.93.11.81.81.61.51.61.61.41.51.41.41.51.31.41.21.21.2-1.21.21.21.31.21.41.11.20.8
Time to tail flick, vehicle, after self-admin0.60.81.21.11.10.91.01.01.00.91.01.01.00.80.91.01.00.80.9-0.70.70.70.80.80.80.80.70.6
Time to tail flick, test, before self-admin0.60.60.80.80.80.80.70.80.80.80.80.80.80.50.50.80.90.80.9-0.80.80.80.80.70.70.80.80.6
Time to tail flick, test, after self-admin3.33.44.51.61.11.60.21.91.91.82.02.02.0-0.01.92.02.12.02.1-2.02.02.02.02.02.02.11.52.1
Delta time to tail flick, vehicle, before/after SA0.70.71.1-1.1-1.0-1.0-0.6-1.0-0.9-0.9-0.9-0.9-0.8-0.8-0.9-0.8-0.7-0.8-0.70.8-0.8-0.8-0.8-0.7-1.0-0.6-0.9-0.5
Delta time to tail flick, test, before/after SA0.20.20.40.2-0.10.2-0.40.40.40.30.50.50.4-0.50.60.40.40.40.4-0.40.40.40.40.50.50.50.10.6
Tibia length1.33.65.4-2.0-1.4-1.9-0.4-2.1-2.1-2.0-2.0-2.1-2.1-0.9-1.7-2.1-1.9-2.0-1.82.0-2.0-2.1-2.0-1.9-2.3-1.8-2.3-1.7
Ambulatory time before self-admin0.30.40.8-0.9-0.9-0.9-0.6-0.7-0.7-0.7-0.7-0.7-0.6-0.7-0.7-0.7-0.6-0.6-0.60.6-0.6-0.6-0.6-0.7-0.6-0.4-0.7-0.3
Ambulatory time after self-admin0.10.20.9-0.2-0.3-0.2-1.00.20.20.10.30.30.4-0.70.30.30.50.30.5-0.30.30.30.30.20.30.60.60.7
Bone: tissue strength2.32.34.7-1.5-2.2-2.0-2.1-1.4-1.4-1.8-1.2-1.3-1.3-2.0-0.7-1.4-1.4-1.4-1.41.5-1.5-1.4-1.3-1.4-0.9-1.2-2.2-0.9
Total heroin consumption0.20.21.30.60.80.51.20.40.40.40.40.30.30.90.40.30.30.20.3-0.20.20.20.20.10.40.30.3-0.0
Bone: trabecular number1.01.62.3-1.0-1.3-1.4-1.4-1.2-1.2-1.5-1.2-1.2-1.2-0.7-1.3-1.2-1.3-1.4-1.51.4-1.4-1.4-1.3-1.3-0.7-1.2-0.8-1.2
Bone: trabecular spacing2.12.73.71.61.51.81.01.81.81.81.81.81.70.81.91.71.71.81.8-1.81.81.81.71.71.41.71.21.5
Bone: trabecular thickness0.20.31.90.30.60.21.4-0.1-0.1-0.1-0.2-0.2-0.21.3-0.5-0.2-0.3-0.3-0.50.3-0.3-0.4-0.4-0.3-0.3-0.50.0-0.7
Bone: trabecular tissue density1.62.33.4-1.6-1.0-1.40.2-1.6-1.7-1.6-1.6-1.6-1.6-0.7-1.4-1.7-1.4-1.6-1.41.7-1.7-1.7-1.6-1.7-1.9-1.5-1.6-1.4
Water consumed over 24 hours0.10.10.70.40.20.20.10.50.50.20.50.40.40.10.80.30.40.30.4-0.20.20.30.40.20.50.4-0.20.3
Number of responses in last shaping day0.20.20.8-0.7-0.8-0.6-0.8-0.5-0.5-0.4-0.4-0.4-0.4-0.9-0.1-0.4-0.3-0.3-0.30.2-0.2-0.2-0.3-0.3-0.4-0.1-0.5-0.0