Hub : Genes

Selenoo

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Selenoo 0.13 0.07 8.6e-13 0.08 0.09 0.09 0.08 1.6e-09 9.7e-10 1.1e-09 3.1e-09
2 Brain intron excision ratio chr7_120171846_120172943 0.04 0.03 2.3e-03 0.01 0.03 0.03 0.02 4.0e-02 1.8e-03 1.9e-03 6.6e-03
3 Adipose mRNA stability Selenoo 0.23 0.1 0.0e+00 0.11 0.16 0.17 0.17 2.3e-12 5.4e-18 1.1e-18 1.5e-18
4 Brain mRNA stability Selenoo 0.54 0.14 0.0e+00 0.36 0.42 0.4 0.41 2.3e-34 7.9e-42 9.8e-40 1.4e-40
5 pVTA gene expression Selenoo 0.46 0.15 0.0e+00 0.44 0.47 0.47 0.47 8.1e-21 1.6e-22 2.2e-22 2.4e-22
6 Brain intron excision ratio chr7_120171788_120174402 0.14 0.07 1.2e-13 0.14 0.15 0.14 0.15 1.1e-12 1.2e-13 1.3e-12 4.0e-14
7 PL gene expression Selenoo 0.38 0.15 0.0e+00 0.44 0.46 0.46 0.46 2.7e-52 5.9e-56 4.0e-56 2.3e-55
8 BLA mRNA stability Selenoo 0.21 0.11 1.4e-10 0.21 0.17 0.19 0.21 2.4e-11 2.2e-09 2.9e-10 2.3e-11
9 Adipose gene expression Selenoo 0.31 0.12 5.6e-17 0.15 0.15 0.16 0.15 1.8e-16 2.3e-16 7.6e-17 2.2e-16
10 NAcc mRNA stability Selenoo 0.09 0.05 6.2e-13 0.11 0.11 0.1 0.11 1.3e-12 1.4e-12 9.4e-12 8.8e-13
11 OFC mRNA stability Selenoo 0.61 0.23 3.5e-09 0.37 0.4 0.4 0.38 1.3e-09 1.1e-10 1.2e-10 6.9e-10
12 NAcc gene expression Selenoo 0.18 0.09 0.0e+00 0.24 0.24 0.24 0.24 2.7e-27 3.3e-27 1.5e-27 9.7e-28
13 IL gene expression Selenoo 0.37 0.16 1.1e-07 0.39 0.37 0.35 0.38 2.2e-10 8.3e-10 3.0e-09 3.0e-10
14 IL mRNA stability Selenoo 0.22 0.13 1.0e-04 0.17 0.15 0.13 0.18 8.4e-05 1.8e-04 5.1e-04 3.8e-05
15 LHb mRNA stability Selenoo 0.39 0.22 1.5e-04 0.18 0.16 0.14 0.17 3.9e-05 1.4e-04 2.8e-04 6.3e-05
16 OFC gene expression Selenoo 0.58 0.19 5.1e-11 0.5 0.48 0.46 0.49 1.5e-13 3.3e-13 1.8e-12 3.0e-13
17 LHb gene expression Selenoo 0.33 0.16 1.1e-05 0.2 0.19 0.19 0.18 1.6e-05 3.3e-05 2.5e-05 5.7e-05
18 PL mRNA stability Selenoo 0.17 0.08 0.0e+00 0.23 0.22 0.22 0.22 5.6e-25 2.8e-23 7.8e-24 4.6e-24
19 BLA gene expression Selenoo 0.42 0.16 0.0e+00 0.34 0.34 0.35 0.35 9.6e-19 5.3e-19 8.9e-20 1.5e-19
20 pVTA mRNA stability Selenoo 0.15 0.09 4.5e-07 0.16 0.15 0.15 0.16 1.2e-07 3.9e-07 3.7e-07 2.9e-07
21 Brain gene expression Selenoo 0.5 0.14 0.0e+00 0.49 0.54 0.53 0.53 8.3e-52 6.0e-59 1.3e-57 7.3e-58
22 Liver gene expression Selenoo 0.26 0.1 0.0e+00 0.22 0.24 0.23 0.24 1.8e-24 2.0e-26 8.2e-26 5.6e-26

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.91.62.5-0.9-1.01.1-1.3-1.31.41.3-1.40.6-1.3-1.2-1.41.3-1.31.31.31.60.91.31.4-1.4-1.3
Area under the delay curve1.31.42.6-0.2-0.60.3-0.9-1.11.11.3-1.2-1.0-1.3-1.1-1.31.3-1.31.31.31.31.41.31.3-1.4-1.6
BMI with tail5.317.222.24.64.7-4.54.54.4-4.4-4.33.8-3.04.14.44.1-4.24.1-4.1-4.1-4.0-4.0-4.0-4.03.93.3
BMI without tail3.26.58.22.62.9-2.32.62.8-2.7-2.82.3-1.42.72.72.6-2.62.6-2.6-2.6-2.5-2.8-2.6-2.52.52.3
Body weight2.410.213.93.73.7-3.73.63.5-3.4-3.33.3-2.63.23.33.1-2.92.9-2.9-2.9-3.0-3.1-3.1-3.03.02.4
Weight adjusted by age4.34.87.02.62.6-2.42.42.4-2.2-2.22.4-1.62.22.12.1-2.22.2-2.2-2.2-2.2-2.2-2.0-2.12.01.6
Bone surface0.81.42.7-0.1-0.40.3-1.0-1.11.31.2-1.3-0.7-1.3-1.0-1.41.3-1.31.31.31.40.81.31.4-1.5-1.7
Bone volume1.11.82.8-0.5-0.80.7-1.2-1.41.51.4-1.6-0.5-1.5-1.2-1.51.4-1.41.41.41.71.21.51.5-1.6-1.7
Breakpoint value in progressive ratio session1.01.12.11.21.2-1.21.11.2-1.1-1.11.4-1.01.01.01.1-0.80.9-0.9-0.9-0.9-1.0-1.0-0.91.00.8
Number of licking bursts0.10.10.3-0.4-0.30.4-0.2-0.10.20.2-0.00.5-0.0-0.2-0.10.4-0.40.40.40.3-0.10.00.1-0.00.0
Context. condit. distance diff. score1.82.22.70.91.2-0.81.41.5-1.5-1.61.60.11.61.41.6-1.61.6-1.6-1.6-1.6-1.6-1.6-1.51.61.6
Locomotion velocity, session 10.10.10.20.50.5-0.50.50.4-0.4-0.30.4-0.30.40.40.4-0.10.1-0.1-0.1-0.3-0.5-0.4-0.30.30.2
Locomotion distance, session 12.43.14.1-1.2-1.51.1-1.7-1.81.91.9-1.8-0.0-1.9-1.8-1.92.0-2.02.02.01.81.81.91.8-1.9-1.8
Locomotion velocity, session 20.70.81.41.11.1-1.21.11.0-1.0-0.90.8-0.41.01.11.0-0.50.5-0.5-0.5-0.8-1.1-0.9-0.90.90.7
Locomotion distance, session 21.11.62.2-0.9-1.10.9-1.3-1.31.51.3-1.3-0.0-1.3-1.3-1.31.4-1.41.41.41.21.31.51.2-1.4-1.3
Locomotion velocity, session 30.40.44.3-1.0-0.51.1-0.30.2-0.1-0.30.42.10.4-0.00.4-0.20.2-0.2-0.2-0.3-0.7-0.5-0.30.60.9
Locomotion distance, session 30.10.10.8-0.6-0.40.4-0.2-0.30.20.1-0.50.9-0.1-0.1-0.20.0-0.10.00.0-0.00.10.10.1-0.10.1
Stereotopy head waving bouts, day 31.72.03.1-0.9-1.20.8-1.4-1.61.51.5-1.8-0.3-1.6-1.3-1.61.4-1.41.41.41.61.61.61.6-1.6-1.6
Stereotopy head waving duration, day 30.60.81.2-0.9-1.00.9-1.0-1.01.00.9-1.10.3-0.9-0.8-0.90.7-0.70.70.71.01.00.90.9-0.9-0.8
Locomotion velocity, session 71.31.42.40.10.4-0.31.10.8-1.2-1.30.60.91.21.31.1-1.51.5-1.5-1.5-1.5-0.8-1.4-1.41.31.5
Locomotion distance, session 70.40.50.80.20.3-0.30.80.6-0.8-0.70.60.20.70.70.7-0.80.8-0.8-0.8-0.9-0.4-0.9-0.90.90.9
Stereotopy head waving bouts, day 70.70.71.3-0.8-0.71.1-1.1-0.71.00.8-0.70.7-0.8-1.0-0.80.9-0.90.90.90.90.30.91.0-0.9-0.7
Stereotopy head waving duration, day 71.21.42.6-1.5-1.31.6-1.5-1.21.21.1-1.21.3-1.1-1.2-1.11.2-1.21.21.21.20.71.01.2-1.1-0.8
Locomotion velocity, session 81.31.52.70.71.0-0.61.11.2-1.2-1.41.00.61.41.41.4-1.21.3-1.2-1.2-1.4-1.6-1.3-1.41.31.4
Locomotion distance, session 80.50.81.31.11.1-0.90.81.0-0.8-0.91.0-0.80.90.80.8-0.80.8-0.8-0.8-0.9-1.1-0.7-0.80.70.6
Degree of sensitization distance1.61.62.61.61.5-1.41.51.4-1.3-1.31.4-1.31.21.21.2-1.11.2-1.2-1.2-1.1-1.2-1.2-1.31.10.9
Degree of sensitization stereotypy0.40.41.4-0.9-0.61.2-0.8-0.40.60.5-0.21.2-0.3-0.7-0.40.6-0.60.60.60.4-0.10.40.5-0.4-0.2
Conditioned locomotion0.40.50.90.50.7-0.50.70.8-0.7-0.80.7-0.10.80.80.9-0.50.6-0.5-0.5-0.7-0.7-0.9-0.90.80.8
Cocaine response after cond. corrected1.41.62.21.11.3-1.11.31.4-1.4-1.31.3-0.21.41.31.3-1.21.2-1.2-1.2-1.3-1.5-1.3-1.31.31.2
Cocaine response after cond. not corrected3.33.65.31.51.9-1.41.92.1-2.0-2.02.0-0.02.11.92.0-1.91.9-1.9-1.9-2.0-2.3-1.9-2.02.01.9
Cocaine response before conditioning1.21.41.91.01.2-1.01.21.2-1.2-1.31.0-0.11.21.31.3-1.41.4-1.4-1.4-1.3-1.3-1.2-1.21.21.1
Saline control response1.31.74.32.11.9-1.91.51.4-1.2-1.21.2-1.71.11.41.1-1.01.0-1.0-1.0-1.1-1.2-1.0-1.10.90.5
Bone: connectivity density0.71.11.5-0.9-0.81.1-1.1-1.01.11.1-1.11.0-1.0-0.9-1.11.2-1.21.21.21.20.51.01.1-1.1-1.0
Bone: cortical apparent density2.53.35.0-2.2-2.22.1-1.9-2.01.91.8-1.91.5-1.8-1.8-1.71.6-1.61.61.61.82.01.71.8-1.6-1.3
Bone: cortical area0.71.14.91.61.3-1.81.30.7-0.9-0.80.4-2.20.51.10.6-1.01.0-1.0-1.0-0.6-0.2-0.7-0.80.50.2
Bone: cortical porosity0.40.52.41.41.2-1.30.80.6-0.5-0.40.5-1.60.30.60.2-0.20.2-0.2-0.20.0-0.5-0.1-0.10.1-0.2
Bone: cortical porosity0.80.93.41.81.6-1.61.01.0-0.8-0.71.0-1.80.60.80.6-0.40.5-0.5-0.5-0.3-1.0-0.4-0.40.4-0.0
Bone: cortical thickness0.10.21.10.40.2-0.60.40.0-0.2-0.2-0.1-1.0-0.00.30.0-0.60.6-0.6-0.6-0.10.6-0.2-0.20.10.1
Bone: cortical thickness0.91.12.50.50.5-0.81.10.6-1.0-1.00.5-0.70.81.10.8-1.61.6-1.6-1.6-1.40.0-1.0-1.01.01.0
Bone: cortical tissue density2.33.04.7-2.2-2.22.0-1.9-1.91.81.8-1.81.5-1.8-1.8-1.71.5-1.51.51.51.71.91.61.7-1.6-1.2
Condit. Reinf. active minus inactive responses1.82.03.91.81.7-2.01.71.3-1.5-1.40.8-1.31.41.81.4-1.31.3-1.3-1.3-1.3-1.3-1.3-1.41.20.9
Condit. Reinf. active-inactive response ratio0.20.20.50.50.5-0.60.50.3-0.6-0.50.0-0.20.50.70.4-0.40.5-0.5-0.5-0.4-0.6-0.5-0.40.40.3
Condit. Reinf. active responses2.63.25.02.12.1-2.22.11.7-1.9-1.81.3-1.41.82.21.8-1.71.7-1.7-1.7-1.7-1.7-1.7-1.81.61.3
Condit. Reinf. inactive responses1.61.92.91.71.7-1.71.61.4-1.4-1.41.3-1.21.41.61.4-1.31.3-1.3-1.3-1.4-1.3-1.3-1.41.31.0
Incentive salience index mean2.83.36.62.42.3-2.62.21.7-1.9-1.81.2-1.81.72.21.7-1.71.7-1.7-1.7-1.7-1.6-1.6-1.71.51.1
Condit. Reinf. lever presses2.22.95.72.32.2-2.42.01.7-1.7-1.61.4-1.71.62.01.6-1.51.5-1.5-1.5-1.6-1.5-1.5-1.61.41.0
Condit. Reinf. active minus inactive responses0.30.44.51.00.5-1.30.6-0.2-0.10.1-0.4-2.1-0.30.3-0.20.1-0.10.10.10.20.80.10.1-0.3-0.7
Condit. Reinf. active-inactive response ratio0.10.11.00.50.2-0.80.5-0.1-0.2-0.0-0.3-1.0-0.00.3-0.0-0.10.1-0.1-0.1-0.00.5-0.1-0.1-0.0-0.2
Condit. Reinf. active responses0.81.17.21.81.3-2.11.30.6-0.8-0.60.2-2.70.41.10.5-0.60.6-0.6-0.6-0.50.1-0.5-0.60.3-0.2
Condit. Reinf. inactive responses0.91.12.81.61.4-1.61.31.0-1.0-1.00.8-1.70.81.10.9-0.90.9-0.9-0.9-0.9-0.7-0.8-0.90.80.5
Condit. Reinf. lever presses1.52.05.12.11.8-2.21.81.3-1.4-1.31.1-2.21.21.61.2-1.21.2-1.2-1.2-1.0-0.9-1.2-1.21.10.6
Condit. Reinf. lever reinforcers received0.71.07.11.81.2-2.01.20.5-0.7-0.50.2-2.70.31.00.4-0.50.5-0.5-0.5-0.40.2-0.4-0.40.2-0.3
Conditioned reinforcement - actives0.50.50.80.90.9-0.80.80.8-0.7-0.70.9-0.50.70.60.7-0.60.6-0.6-0.6-0.6-0.5-0.7-0.60.60.5
Conditioned reinforcement - inactives0.40.50.90.40.6-0.40.70.8-0.7-0.70.90.20.70.60.8-0.60.7-0.6-0.6-0.6-0.7-0.8-0.70.80.8
Conditioned locomotion3.74.55.82.32.4-2.12.32.3-2.2-2.22.3-1.32.22.12.1-2.12.1-2.1-2.1-2.2-1.9-2.1-2.22.01.7
Patch foraging indifference point 0 sec0.50.81.50.91.0-0.90.90.8-0.9-0.90.7-0.40.90.90.8-1.21.1-1.1-1.1-1.0-0.9-0.8-0.80.80.7
Patch foraging indifference point AUC0.91.05.51.10.5-0.9-0.3-0.50.60.8-0.7-2.4-0.9-0.5-0.91.1-0.90.90.91.10.71.00.9-1.1-1.6
Delay disc. indifference point, 0s delay0.60.75.51.71.3-1.70.80.5-0.5-0.4-0.1-2.40.20.70.2-0.10.2-0.1-0.1-0.2-0.2-0.1-0.2-0.0-0.5
Delay disc. indifference point, 16s delay0.40.41.00.30.0-0.2-0.3-0.40.50.6-0.5-0.9-0.6-0.5-0.60.8-0.80.80.80.70.60.70.7-0.7-1.0
Delay disc. indifference point, 2s delay2.73.06.70.5-0.3-0.4-0.9-1.61.51.7-1.8-2.4-1.9-1.2-1.91.8-1.81.81.81.82.02.01.8-2.1-2.6
Delay disc. indifference point, 24s delay0.70.61.30.80.8-0.60.90.8-0.9-0.71.1-0.10.90.80.8-0.80.8-0.8-0.8-0.9-0.6-0.9-0.90.80.7
Delay disc. indifference point, 4s delay1.51.62.7-0.2-0.60.1-1.1-1.11.31.2-1.3-1.2-1.4-1.2-1.41.4-1.41.41.41.41.21.51.4-1.4-1.6
Delay disc. indifference point, 8s delay1.31.31.9-0.8-1.01.0-1.1-1.31.21.3-1.0-0.1-1.3-1.2-1.31.1-1.21.11.11.21.41.21.2-1.3-1.3
Indifference point function ln k2.43.34.41.11.4-1.11.81.9-2.0-2.01.7-0.21.91.82.0-2.12.1-2.1-2.1-2.1-1.6-2.1-1.92.12.1
Indifference point function log k2.43.34.41.11.4-1.11.81.9-2.0-2.01.7-0.21.91.82.0-2.12.1-2.1-2.1-2.1-1.6-2.1-1.92.12.1
Patch foraging total patch changes 0 sec0.20.40.80.50.6-0.50.60.5-0.6-0.60.4-0.00.60.60.5-0.90.8-0.8-0.8-0.7-0.6-0.5-0.60.50.5
Patch foraging total patch changes 12 sec0.30.33.01.20.9-1.10.40.2-0.1-0.2-0.2-1.70.00.4-0.0-0.30.3-0.3-0.3-0.1-0.00.1-0.1-0.2-0.5
Patch foraging total patch changes 18 sec1.11.52.9-0.2-0.60.0-0.9-1.31.21.3-1.6-0.9-1.4-1.0-1.41.2-1.31.21.21.21.21.41.4-1.5-1.7
Patch foraging total patch changes 24 sec0.20.20.90.1-0.1-0.4-0.2-0.60.30.4-0.9-0.5-0.5-0.0-0.50.2-0.20.20.20.30.70.50.4-0.6-0.7
Patch foraging total patch changes 6 sec0.10.21.10.90.6-0.6-0.10.10.20.20.0-1.1-0.2-0.2-0.30.1-0.20.20.20.3-0.10.40.3-0.5-0.7
Patch foraging time to switch 0 sec0.30.51.1-1.0-1.01.0-0.8-0.80.70.7-0.71.0-0.6-0.6-0.60.7-0.70.70.70.50.60.50.6-0.6-0.4
Patch foraging water rate 0 sec0.81.31.70.91.0-1.01.11.3-1.1-1.21.1-0.51.11.01.2-1.31.3-1.3-1.3-1.2-1.0-1.2-1.11.21.2
Patch foraging water rate 12 sec2.33.54.41.71.8-1.82.02.0-2.1-1.91.8-1.11.81.81.8-2.12.1-2.1-2.1-2.0-1.4-1.9-1.91.91.7
Patch foraging water rate 18 sec3.85.17.11.31.8-1.42.12.4-2.3-2.42.50.12.32.02.3-2.72.6-2.6-2.6-2.6-2.2-2.4-2.32.52.6
Patch foraging water rate 24 sec1.01.42.20.50.9-0.50.91.4-1.1-1.31.30.41.20.91.2-1.41.4-1.4-1.4-1.3-1.4-1.2-1.11.31.5
Patch foraging water rate 6 sec0.71.01.40.70.9-0.81.01.2-1.0-1.11.1-0.21.00.91.1-1.11.1-1.1-1.1-1.0-0.9-1.1-1.01.21.2
Seeking ratio, delayed vs. immediate footshock0.70.81.0-0.9-1.01.0-0.9-1.00.90.9-0.80.6-0.9-0.9-0.91.0-0.90.90.90.90.60.81.0-0.8-0.7
Distance traveled before self-admin1.31.41.9-1.3-1.41.2-1.3-1.31.31.2-1.20.6-1.2-1.2-1.21.2-1.11.11.11.11.31.21.1-1.1-0.9
Distance traveled after self-admin0.10.10.9-0.3-0.10.20.10.2-0.3-0.20.10.90.30.30.4-0.10.2-0.2-0.2-0.3-0.0-0.5-0.30.40.5
Extensor digitorum longus weight0.41.52.01.01.2-1.11.21.3-1.3-1.31.3-0.51.21.31.2-1.41.4-1.4-1.4-1.1-1.2-1.2-1.21.31.2
Bone: elastic displacement0.40.50.9-0.6-0.50.9-0.9-0.50.90.7-0.40.7-0.7-0.8-0.90.6-0.60.60.60.90.10.80.9-0.7-0.6
Bone: elastic work0.30.30.70.80.8-0.70.50.7-0.3-0.60.7-0.90.40.40.3-0.70.6-0.6-0.6-0.3-0.6-0.3-0.40.40.3
Bone: endosteal estimation0.20.52.51.21.0-1.20.80.6-0.6-0.50.4-1.60.40.60.3-0.30.3-0.3-0.3-0.4-0.7-0.4-0.50.3-0.0
Bone: endosteal perimeter1.02.014.02.82.1-2.91.60.9-1.0-0.70.3-3.70.51.40.5-0.40.4-0.4-0.4-0.4-0.7-0.4-0.60.2-0.6
Epididymis fat weight2.04.69.42.82.7-3.12.62.0-2.1-2.11.5-2.32.02.62.0-2.02.1-2.1-2.1-2.0-1.6-1.8-2.01.71.3
Delta time in closed arm before/after self-admin0.30.30.50.10.3-0.00.30.5-0.4-0.50.70.30.50.30.4-0.70.7-0.7-0.7-0.7-0.4-0.5-0.70.50.6
Delta time in open arm before/after self-admin0.10.10.3-0.1-0.2-0.0-0.2-0.30.30.3-0.5-0.5-0.4-0.2-0.30.5-0.40.40.40.40.40.30.4-0.3-0.4
Diff in mean of infusions in LGA sessions2.12.32.81.51.6-1.41.51.6-1.5-1.61.6-0.71.51.51.5-1.61.6-1.6-1.6-1.6-1.7-1.4-1.61.41.3
Delay discount exponential model param1.11.22.00.30.7-0.40.91.1-1.1-1.21.10.71.21.11.2-1.21.2-1.2-1.2-1.2-1.3-1.2-1.21.31.4
Extinction: sum of active levers before priming0.10.10.60.50.3-0.5-0.00.00.10.20.1-0.8-0.2-0.2-0.20.4-0.40.40.40.4-0.20.20.4-0.3-0.5
Active lever presses in extinction session 62.02.02.51.31.5-1.31.41.6-1.5-1.51.6-0.61.51.41.5-1.31.4-1.4-1.4-1.4-1.3-1.5-1.41.41.3
Bone: final force0.10.11.20.3-0.0-0.50.3-0.2-0.10.0-0.3-1.1-0.20.2-0.1-0.20.2-0.2-0.20.10.6-0.0-0.1-0.1-0.2
Bone: final moment0.10.10.6-0.0-0.2-0.1-0.0-0.40.10.2-0.5-0.7-0.4-0.1-0.3-0.00.0-0.0-0.00.40.70.20.1-0.2-0.3
Food consumed during 24 hour testing period2.83.44.01.61.8-1.61.91.9-1.8-1.91.9-0.61.91.91.8-2.02.0-2.0-2.0-1.9-1.8-1.9-2.01.91.8
Glucose0.50.71.2-0.2-0.50.3-0.8-0.81.00.9-0.9-0.5-1.0-0.9-1.00.9-0.80.80.80.80.91.10.9-1.0-1.1
Heart weight0.40.62.5-1.5-1.21.4-0.9-0.80.50.5-0.71.6-0.5-0.6-0.40.2-0.30.30.30.40.50.30.5-0.30.1
Delay discount hyperbolic model param1.31.32.50.20.6-0.20.91.1-1.1-1.21.21.01.31.01.3-1.21.3-1.2-1.2-1.2-1.3-1.3-1.21.41.6
Intermittent access intake day 1-15 change0.80.71.00.70.8-0.60.81.0-0.8-0.91.0-0.10.90.70.9-1.01.0-1.0-1.0-0.9-0.9-0.8-0.90.90.9
Intermittent access intake escalation1.11.11.40.91.1-0.81.01.1-1.0-1.11.1-0.31.11.01.0-1.21.2-1.2-1.2-1.1-1.0-1.0-1.01.01.0
Intermittent access intake escalation 22.52.43.51.81.9-1.71.61.7-1.6-1.61.6-1.01.51.51.5-1.61.6-1.6-1.6-1.5-1.5-1.5-1.41.41.2
Intermitt. access day 1 inactive lever presses1.31.42.71.61.6-1.61.41.3-1.3-1.21.2-1.31.11.21.1-1.01.0-1.0-1.0-1.1-1.2-1.1-1.11.00.7
Intermitt. access day 15 inactive lever presses4.04.46.11.51.9-1.32.02.3-2.2-2.32.50.12.31.92.3-2.22.2-2.2-2.2-2.2-2.4-2.3-2.22.32.3
Intermitt. access escalation Index0.60.61.2-1.1-1.01.0-0.8-0.80.70.7-0.90.9-0.6-0.7-0.60.7-0.70.70.70.60.60.60.6-0.6-0.4
Intermittent access day 1 total infusions0.10.10.30.00.10.00.10.3-0.2-0.20.50.30.30.10.3-0.20.2-0.2-0.2-0.2-0.2-0.3-0.20.30.3
Intermittent access day 15 total infusions0.30.30.80.30.4-0.20.40.6-0.5-0.60.90.20.60.30.6-0.60.6-0.6-0.6-0.5-0.5-0.6-0.50.60.6
Intermittent access terminal intake (last 3 days)2.72.94.71.81.9-1.51.72.0-1.7-1.82.2-0.81.81.51.7-1.81.8-1.8-1.8-1.7-1.6-1.7-1.61.71.5
Intermittent access total infusions0.30.40.90.60.7-0.50.60.8-0.6-0.61.0-0.20.70.50.6-0.60.6-0.6-0.6-0.5-0.5-0.6-0.50.60.5
Intermittent access day 1 locomotion0.10.10.20.20.3-0.20.30.3-0.3-0.30.5-0.10.40.20.3-0.30.3-0.3-0.3-0.3-0.2-0.3-0.30.30.3
Intermittent access day 15 total locomotion0.40.50.70.70.8-0.70.70.8-0.7-0.70.8-0.40.70.60.7-0.70.7-0.7-0.7-0.7-0.6-0.6-0.60.60.6
Intermittent access total locomotion0.70.81.20.50.7-0.40.81.0-0.9-0.91.10.31.00.71.0-1.01.0-1.0-1.0-1.0-0.8-1.0-0.91.01.0
Intermittent access standard deviation0.90.91.70.10.4-0.00.61.0-0.8-1.01.30.91.00.61.0-1.11.1-1.1-1.1-1.0-1.0-1.0-0.91.11.3
Left kidney weight3.910.915.33.03.5-2.73.33.8-3.4-3.53.7-0.63.63.33.6-3.23.2-3.2-3.2-3.3-3.9-3.4-3.33.43.2
Right kidney weight7.721.727.04.75.1-4.44.85.2-4.8-4.95.1-1.74.94.74.8-4.64.6-4.6-4.6-4.6-5.1-4.7-4.74.64.2
Cocaine induced anxiety3.54.15.81.51.8-1.32.02.2-2.1-2.12.40.02.31.92.2-2.02.1-2.0-2.0-2.2-2.2-2.2-2.22.22.2
Post-drug Anxiety3.23.54.91.82.0-1.61.92.1-2.0-2.02.2-0.72.01.81.9-1.81.9-1.8-1.8-2.0-2.1-1.9-1.91.91.7
Baseline Anxiety1.01.01.6-0.5-0.70.4-0.9-1.11.11.0-1.2-0.4-1.3-0.9-1.21.0-1.01.01.01.01.11.21.0-1.2-1.2
Tail length0.61.82.5-1.3-1.41.5-1.5-1.31.31.4-1.30.8-1.3-1.5-1.31.6-1.61.61.61.41.11.21.3-1.3-1.1
Length with tail0.10.30.7-0.0-0.3-0.0-0.3-0.40.40.6-0.1-0.3-0.6-0.5-0.50.8-0.80.80.80.60.50.50.5-0.5-0.7
Length without tail0.51.02.31.31.1-1.51.31.1-1.0-1.01.5-0.80.91.01.0-0.90.8-0.8-0.8-0.9-0.7-0.9-1.01.00.7
Times rat made contact with spout1.11.33.0-0.40.10.50.51.0-1.0-1.01.51.51.20.51.1-1.31.3-1.3-1.3-1.1-1.1-1.3-1.21.41.7
Lifetime Intake0.30.41.10.40.5-0.30.50.7-0.6-0.61.10.10.70.40.7-0.60.6-0.6-0.6-0.5-0.5-0.7-0.50.70.7
Liver weight, left0.10.21.50.40.1-0.5-0.0-0.20.10.3-0.3-1.2-0.4-0.3-0.30.6-0.50.50.50.30.50.30.2-0.4-0.6
Liver weight, right0.81.34.80.4-0.2-0.6-0.5-1.01.01.0-1.3-2.2-1.2-0.7-1.11.1-1.01.01.01.11.41.21.1-1.3-1.6
Locomotor activity0.30.64.01.51.2-1.30.70.6-0.5-0.40.2-2.00.30.60.3-0.40.3-0.3-0.3-0.2-0.5-0.2-0.30.1-0.3
Locomotor testing distance0.50.81.5-0.8-0.81.0-1.0-0.91.00.9-1.20.1-0.9-0.9-0.90.7-0.80.80.81.00.80.91.0-1.0-0.9
Locomotor testing rearing0.60.96.61.20.6-1.1-0.0-0.40.50.6-0.6-2.6-0.8-0.3-0.80.6-0.70.70.70.80.80.90.8-1.0-1.5
Locomotion in novel chamber0.60.72.0-0.40.00.40.40.7-0.6-0.80.91.40.90.60.9-0.90.9-0.9-0.9-0.9-0.5-1.0-0.91.11.4
Locomotion in novel chamber post-restriction0.10.10.50.40.3-0.30.1-0.10.10.1-0.3-0.7-0.20.1-0.10.1-0.10.10.10.10.30.10.2-0.2-0.4
Fecal boli incidents, locomotor time 10.30.40.7-0.8-0.80.8-0.7-0.70.60.6-0.40.7-0.6-0.6-0.60.5-0.50.50.50.50.60.50.5-0.5-0.4
Change in fecal boli incidents, locomotor task0.30.30.90.60.6-0.40.60.6-0.6-0.51.0-0.00.60.40.5-0.60.6-0.6-0.6-0.6-0.4-0.6-0.60.50.4
Time >=10cm from walls, locomotor time 10.50.51.21.11.0-1.10.80.7-0.6-0.60.7-0.90.60.70.5-0.40.5-0.4-0.4-0.4-0.9-0.5-0.40.40.2
Bouts of movement, locomotor time 10.60.61.00.20.4-0.00.60.5-0.7-0.70.90.80.90.80.8-1.01.0-1.0-1.0-1.0-0.7-0.9-1.00.80.9
Total resting periods, locomotor time 10.20.21.2-0.2-0.10.30.20.1-0.3-0.30.61.10.40.30.3-0.50.5-0.5-0.5-0.5-0.3-0.4-0.50.30.5
Rest time, locomotor task time 10.20.32.6-0.7-0.50.8-0.1-0.0-0.1-0.10.41.60.30.10.3-0.30.3-0.3-0.3-0.3-0.1-0.4-0.30.30.6
Distance moved, locomotor task time 10.60.63.01.31.1-1.30.90.8-0.7-0.70.1-1.70.60.70.5-0.50.5-0.5-0.5-0.5-0.6-0.4-0.50.40.2
Vertical activity count, locomotor time 11.61.75.52.01.8-2.01.51.2-1.3-1.10.3-2.31.01.31.0-1.01.0-1.0-1.0-1.0-0.9-1.0-1.00.90.5
Time >=10cm from walls, locomotor time 22.32.54.22.12.0-1.91.81.7-1.7-1.51.7-1.31.51.61.5-1.41.4-1.4-1.4-1.4-1.6-1.5-1.41.41.0
Bouts of movement, locomotor time 20.40.40.6-0.7-0.80.7-0.7-0.70.60.7-0.60.2-0.7-0.7-0.60.7-0.70.70.70.60.70.50.6-0.6-0.5
Total resting periods, locomotor time 20.50.50.7-0.7-0.80.6-0.7-0.80.70.8-0.70.1-0.7-0.7-0.70.7-0.70.70.70.70.80.60.7-0.7-0.6
Rest time, locomotor task time 21.21.43.4-1.9-1.71.7-1.4-1.31.21.1-0.81.7-1.0-1.2-1.00.9-0.90.90.91.01.01.01.0-0.9-0.5
Distance moved, locomotor task time 22.63.05.72.42.3-2.32.01.8-1.8-1.71.1-2.11.61.91.6-1.61.6-1.6-1.6-1.6-1.5-1.5-1.61.41.0
Vertical activity count, locomotor time 23.63.96.92.62.5-2.52.32.0-2.2-1.91.1-2.21.82.11.9-1.91.9-1.9-1.9-1.9-1.6-1.9-1.91.71.2
Light reinforcement 10.30.61.91.41.2-1.30.90.9-0.8-0.70.6-1.20.70.80.7-0.50.5-0.4-0.4-0.5-0.8-0.5-0.50.50.2
Light reinforcement 22.43.27.62.82.5-2.62.12.0-1.7-1.71.7-2.51.61.71.6-1.21.3-1.3-1.3-1.3-1.8-1.4-1.61.40.8
Bone: marrow area0.20.32.21.10.9-1.10.60.4-0.4-0.30.3-1.50.30.50.2-0.10.1-0.1-0.1-0.2-0.5-0.2-0.30.1-0.2
Bone: maximum diameter1.32.46.02.22.0-2.41.91.4-1.6-1.51.0-2.41.21.81.4-1.31.3-1.3-1.3-1.2-1.1-1.3-1.31.20.7
Bone: maximum force0.00.10.80.20.1-0.40.2-0.0-0.0-0.0-0.0-0.9-0.10.1-0.1-0.20.1-0.1-0.10.00.4-0.0-0.10.0-0.1
Bone: maximum moment0.00.00.3-0.0-0.1-0.0-0.1-0.10.20.1-0.1-0.5-0.2-0.2-0.3-0.10.1-0.1-0.10.20.40.20.1-0.1-0.1
Mean time between licks in bursts2.73.96.3-2.5-2.42.4-2.2-2.11.92.0-1.92.1-1.8-2.0-1.81.9-1.91.91.91.91.71.71.8-1.7-1.3
Mean num. licks in bursts0.20.20.6-0.10.00.10.20.4-0.4-0.40.60.40.30.10.3-0.80.7-0.8-0.8-0.6-0.2-0.4-0.40.50.6
Cd content in liver0.20.20.6-0.5-0.60.3-0.4-0.50.30.5-0.40.1-0.5-0.5-0.40.5-0.50.50.50.30.80.30.4-0.4-0.3
Co content in liver0.40.51.41.21.1-1.10.80.8-0.7-0.60.6-0.90.60.80.5-0.50.5-0.5-0.5-0.5-0.9-0.5-0.50.50.2
Cu content in liver1.61.95.8-2.4-2.32.0-1.5-1.51.11.3-1.41.9-1.1-1.3-1.01.1-1.11.11.10.81.60.90.8-0.8-0.3
Fe content in liver0.10.11.10.60.3-0.60.50.1-0.4-0.2-0.1-1.10.10.40.1-0.20.2-0.2-0.2-0.30.3-0.2-0.20.1-0.1
K content in liver0.10.10.4-0.2-0.1-0.0-0.1-0.30.20.2-0.60.7-0.10.10.00.4-0.40.40.40.1-0.00.20.1-0.2-0.2
Mg content in liver0.70.71.1-0.3-0.40.3-0.8-0.80.90.9-1.00.2-0.8-0.6-0.71.1-1.11.11.10.90.51.00.8-1.0-1.0
Mn content in liver0.20.20.9-0.2-0.10.4-0.5-0.30.30.4-0.41.0-0.3-0.2-0.20.8-0.80.80.80.6-0.30.30.5-0.4-0.4
Na content in liver3.63.87.1-0.9-1.50.4-1.4-2.31.72.0-2.7-0.7-2.1-1.4-2.02.2-2.22.22.21.92.42.01.9-2.1-2.3
Rb content in liver0.40.50.7-0.3-0.50.3-0.7-0.70.70.8-0.80.1-0.7-0.6-0.70.7-0.70.70.70.80.70.80.7-0.8-0.8
Se content in liver0.70.91.50.30.7-0.20.71.0-1.0-1.00.91.01.10.91.2-0.90.9-0.9-0.9-1.0-1.2-1.1-0.91.11.2
Sr content in liver1.41.22.8-1.7-1.61.5-1.2-1.21.11.1-1.11.4-1.0-1.1-0.91.0-1.01.01.00.91.10.80.9-0.8-0.5
Zn content in liver0.00.00.1-0.3-0.20.2-0.0-0.0-0.0-0.1-0.10.30.00.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.10.3
Bone: minimum diameter0.50.93.71.51.2-1.71.20.6-0.9-0.80.3-1.90.61.10.6-0.80.8-0.8-0.8-0.6-0.5-0.6-0.80.50.2
Time in familiar zone, hab. session 10.30.31.3-0.3-0.00.50.00.5-0.3-0.30.71.10.50.10.5-0.40.4-0.4-0.4-0.4-0.7-0.5-0.50.60.8
Time in novel zone, hab. session 10.60.61.2-0.1-0.40.0-0.6-0.80.90.7-1.0-0.6-0.9-0.5-1.00.7-0.70.70.70.90.81.00.9-1.0-1.1
Total zone transitions, hab. session 12.73.84.6-1.5-1.81.5-2.0-1.92.12.1-1.7-0.1-2.1-2.1-2.12.1-2.12.12.11.92.12.12.0-2.1-2.0
Total locomotion distance, hab. session 10.40.51.10.2-0.1-0.0-0.6-0.30.80.7-0.1-1.0-0.7-0.9-0.80.8-0.80.80.80.70.50.90.8-0.8-1.0
Locomotion velocity, hab. session 10.50.71.50.2-0.1-0.1-0.6-0.50.80.8-0.3-1.2-0.8-0.9-0.90.9-0.90.90.90.80.71.00.9-1.0-1.2
Time in familiar zone, hab. session 22.02.03.00.61.0-0.81.31.4-1.6-1.51.30.71.61.51.5-1.61.6-1.6-1.6-1.5-1.5-1.7-1.51.61.7
Time in novel zone, hab. session 22.52.53.2-1.2-1.31.4-1.7-1.61.81.6-1.50.3-1.6-1.6-1.71.6-1.61.61.61.71.41.81.7-1.7-1.6
Total zone transitions, hab. session 20.10.10.20.10.1-0.00.10.3-0.1-0.30.4-0.10.30.10.3-0.30.3-0.3-0.3-0.4-0.2-0.2-0.40.30.3
Total locomotion distance, hab. session 20.60.81.71.11.2-0.90.81.2-0.7-0.91.3-0.80.90.60.8-0.80.8-0.8-0.8-0.9-1.1-0.7-0.80.80.6
Locomotion velocity, hab. session 20.60.71.61.21.2-1.00.81.1-0.7-0.81.3-0.90.80.60.8-0.70.7-0.7-0.7-0.8-1.0-0.6-0.70.70.5
Novel to familiar place preference ratio0.50.53.4-1.2-0.91.2-0.7-0.60.40.4-0.51.9-0.3-0.4-0.30.5-0.50.50.50.50.10.10.4-0.20.1
Novelty place preference0.40.43.9-1.1-0.81.2-0.5-0.40.20.3-0.32.0-0.1-0.3-0.10.3-0.30.40.40.3-0.1-0.10.2-0.00.3
Time in novel zone, NPP test0.50.55.0-1.3-0.91.4-0.7-0.40.30.3-0.32.2-0.2-0.4-0.20.4-0.40.40.40.4-0.1-0.00.3-0.00.3
Total zone transitions, NPP test0.81.11.7-1.0-1.11.1-1.2-1.01.31.1-0.80.2-1.1-1.3-1.11.0-1.01.01.00.91.11.21.0-1.1-0.9
Total locomotion distance, NPP test0.10.10.50.40.3-0.2-0.20.00.30.20.1-0.7-0.2-0.3-0.30.3-0.30.30.30.20.10.50.3-0.4-0.5
Locomotion velocity, NPP test0.10.10.70.50.4-0.3-0.10.20.20.10.2-0.8-0.1-0.2-0.10.2-0.20.20.20.1-0.00.30.2-0.2-0.4
Intraocular pressure0.20.32.91.00.7-1.10.70.1-0.5-0.2-0.5-1.70.00.60.0-0.40.2-0.2-0.2-0.1-0.1-0.20.1-0.0-0.3
Delta distance traveled before/after self-admin3.43.65.01.31.7-1.31.92.0-2.1-2.01.90.42.12.02.2-2.02.0-2.0-2.0-1.9-1.9-2.2-1.92.12.1
Delta ambulatory time before/after self-admin1.92.12.91.01.2-0.91.41.5-1.6-1.51.40.31.61.51.7-1.51.5-1.5-1.5-1.5-1.5-1.7-1.51.61.6
Parametrial fat weight0.10.20.40.00.1-0.10.20.4-0.3-0.50.30.00.40.30.4-0.60.6-0.6-0.6-0.5-0.4-0.3-0.50.50.6
Pavlov. Cond. lever latency1.31.63.0-1.6-1.61.7-1.5-1.31.31.2-1.01.0-1.2-1.5-1.31.2-1.11.11.11.11.11.11.2-1.1-0.8
Pavlov. Cond. magazine entry latency0.10.10.7-0.2-0.3-0.0-0.1-0.50.40.2-0.80.1-0.30.1-0.3-0.10.0-0.0-0.00.20.70.30.2-0.3-0.3
Pavlov. Cond. change in total contacts0.30.31.60.90.7-1.20.80.1-0.5-0.4-0.5-1.20.30.90.3-0.50.5-0.5-0.5-0.30.1-0.3-0.30.2-0.1
Pavlov. Cond. index score0.20.30.80.60.5-0.90.70.2-0.4-0.5-0.1-0.50.40.80.5-0.60.6-0.6-0.6-0.5-0.1-0.4-0.50.40.2
Pavlov. Cond. latency score0.40.61.40.90.8-1.21.00.5-0.7-0.70.1-0.70.71.10.7-0.90.8-0.8-0.8-0.7-0.3-0.6-0.70.60.4
Pavlov. Cond. lever contacts2.22.64.42.01.9-2.11.91.5-1.6-1.61.1-1.11.62.01.6-1.61.6-1.6-1.6-1.5-1.4-1.5-1.61.41.1
Pavlov. Cond. magazine entry number0.10.10.6-0.10.10.3-0.10.4-0.2-0.10.70.30.2-0.20.20.2-0.20.20.2-0.1-0.6-0.3-0.10.20.3
Pavlov. Cond. intertrial magazine entries1.31.63.11.81.6-1.81.51.3-1.5-1.21.1-1.61.11.31.2-1.01.0-0.9-0.9-1.0-1.3-1.2-1.11.00.7
Pavlov. Cond. lever-magazine prob. diff.0.20.20.80.60.4-0.90.60.2-0.4-0.4-0.2-0.60.30.70.4-0.50.5-0.5-0.5-0.40.0-0.3-0.40.30.2
Pavlov. Cond. response bias0.40.51.10.90.8-1.10.90.5-0.6-0.70.2-0.60.61.00.6-0.90.9-0.9-0.9-0.6-0.4-0.5-0.70.50.4
Pavlov. Cond. lever latency1.92.63.3-1.5-1.61.7-1.8-1.61.71.7-1.41.0-1.6-1.8-1.71.7-1.71.71.71.51.31.71.6-1.6-1.4
Pavlov. Cond. magazine entry latency0.80.91.30.90.8-1.11.20.8-1.1-1.00.7-0.70.91.11.0-1.01.0-1.0-1.0-0.9-0.6-1.0-1.01.00.8
Pavlov. Cond. change in total contacts0.50.63.61.20.9-1.51.10.5-0.7-0.60.4-1.90.50.80.5-0.60.6-0.6-0.6-0.50.1-0.6-0.60.40.1
Pavlov. Cond. index score1.31.72.51.41.4-1.61.61.3-1.4-1.31.2-1.21.31.41.3-1.31.3-1.3-1.3-1.2-1.0-1.3-1.31.31.0
Pavlov. Cond. latency score1.82.33.11.51.5-1.71.81.5-1.6-1.51.4-1.11.51.61.5-1.61.6-1.6-1.6-1.5-1.2-1.6-1.51.51.3
Pavlov. Cond. lever contacts1.52.12.61.41.5-1.51.61.5-1.5-1.51.4-0.91.51.61.5-1.51.5-1.5-1.5-1.4-1.3-1.5-1.41.41.3
Pavlov. Cond. magazine entry number0.91.11.7-1.2-1.11.3-1.3-1.01.11.1-0.91.0-1.0-1.2-1.01.1-1.11.11.11.10.71.11.1-1.0-0.8
Pavlov. Cond. intertrial magazine entries0.20.31.7-0.7-0.50.9-0.7-0.10.40.40.11.3-0.3-0.7-0.20.4-0.40.40.40.4-0.10.40.4-0.2-0.0
Pavlov. Cond. lever-magazine prob. diff.1.21.52.11.31.3-1.41.41.2-1.3-1.21.2-1.11.21.31.2-1.21.2-1.2-1.2-1.1-0.9-1.3-1.21.21.0
Pavlov. Cond. response bias0.71.01.41.11.0-1.21.20.9-1.0-1.00.8-0.91.01.11.0-1.01.0-1.0-1.0-0.9-0.8-1.0-1.00.90.8
Time in closed arm before self-admin1.31.45.00.60.0-0.7-0.3-1.00.71.0-1.7-2.2-1.2-0.4-1.01.3-1.31.31.31.31.21.11.3-1.3-1.7
Time in closed arm after self-admin0.40.44.11.30.9-1.30.60.2-0.3-0.1-0.2-2.0-0.00.5-0.0-0.10.1-0.1-0.1-0.1-0.20.0-0.1-0.2-0.6
Time in open arm before self-admin0.30.33.2-0.8-0.50.8-0.20.2-0.0-0.20.71.80.3-0.20.2-0.30.3-0.3-0.3-0.3-0.4-0.3-0.30.40.7
Time in open arm after self-admin0.10.10.7-0.4-0.20.3-0.10.1-0.0-0.10.20.80.2-0.10.2-0.10.1-0.1-0.1-0.2-0.1-0.2-0.20.20.4
Bone: periosteal estimation0.61.26.21.81.4-2.01.30.8-0.9-0.80.5-2.50.61.10.6-0.80.8-0.8-0.8-0.6-0.6-0.6-0.80.50.1
Bone: periosteal perimeter1.22.010.62.52.0-2.71.71.0-1.2-1.00.5-3.30.71.50.8-0.90.9-0.9-0.9-0.6-0.7-0.7-0.90.6-0.1
Bone: post-yield work0.50.71.5-1.2-1.21.1-0.9-0.90.80.8-0.70.7-0.8-1.0-0.80.7-0.70.70.70.61.10.70.6-0.7-0.5
Progressive ratio test 1 active lever presses0.40.42.0-0.5-0.20.60.20.5-0.5-0.51.11.40.70.20.7-0.50.5-0.5-0.5-0.5-0.5-0.8-0.50.81.1
Progressive ratio test 1 breakpoint0.50.51.9-0.4-0.10.50.30.6-0.6-0.61.21.40.80.20.8-0.60.6-0.6-0.6-0.5-0.6-0.8-0.50.91.1
Progressive ratio test 1 inactive lever presses0.30.30.70.10.20.00.40.6-0.5-0.50.90.50.60.30.6-0.60.6-0.6-0.6-0.5-0.5-0.7-0.50.70.7
Progressive ratio test 2 active lever presses0.40.40.80.60.7-0.60.60.8-0.7-0.70.9-0.10.70.50.7-0.60.6-0.6-0.6-0.5-0.6-0.7-0.50.60.6
Progressive ratio test 2 breakpoint0.30.30.60.60.7-0.60.60.7-0.6-0.60.8-0.20.60.50.6-0.50.5-0.5-0.5-0.4-0.5-0.6-0.40.60.5
Progressive ratio test 2 inactive lever presses0.40.51.00.80.8-0.70.70.9-0.7-0.71.0-0.50.70.60.7-0.70.7-0.7-0.7-0.6-0.8-0.6-0.50.60.5
Incentive Sensitization - Responses0.50.51.31.11.0-1.10.80.7-0.6-0.60.5-1.00.60.70.6-0.50.5-0.5-0.5-0.5-0.5-0.5-0.50.40.2
Incentive Sensitization - Breakpoint0.40.41.01.00.9-1.00.70.6-0.6-0.60.4-0.80.50.60.5-0.50.5-0.5-0.5-0.4-0.5-0.4-0.40.40.2
Sum of active levers in priming session hrs 5-60.30.30.50.60.6-0.70.60.5-0.5-0.60.6-0.30.60.60.6-0.40.5-0.5-0.5-0.5-0.5-0.5-0.50.50.4
Progressive ratio0.30.41.10.10.4-0.00.40.6-0.5-0.60.80.60.80.50.7-0.60.5-0.5-0.5-0.5-1.0-0.7-0.60.70.8
Food seeking constrained by brief footshock2.83.45.02.22.2-1.91.92.2-1.9-1.82.2-1.51.91.61.9-1.71.7-1.6-1.6-1.6-2.1-1.8-1.81.71.4
Seeking ratio, punishment vs. effort0.10.21.80.70.5-0.70.30.2-0.2-0.10.0-1.4-0.10.10.0-0.00.1-0.1-0.1-0.10.2-0.0-0.1-0.0-0.2
Retroperitoneal fat weight1.13.66.12.52.5-2.32.02.2-2.0-1.91.8-1.71.92.02.0-1.51.5-1.5-1.5-1.6-2.1-1.7-1.81.71.3
Reaction time number correct0.71.01.4-1.0-1.11.0-1.1-1.01.01.0-1.00.4-1.0-1.0-0.91.1-1.01.11.11.21.10.91.1-0.9-0.8
Reaction time mean minus median0.10.10.20.50.4-0.40.30.3-0.3-0.30.3-0.30.30.40.2-0.30.3-0.3-0.3-0.3-0.3-0.2-0.30.20.1
Reaction time mean minus median AUC0.10.10.30.20.3-0.00.20.3-0.2-0.30.50.10.30.30.4-0.30.3-0.3-0.3-0.3-0.4-0.3-0.30.30.3
Reaction time num false alarms0.00.10.2-0.1-0.20.0-0.2-0.40.30.2-0.40.3-0.30.0-0.20.1-0.10.10.1-0.00.40.30.3-0.3-0.3
Reaction time num false alarms AUC0.00.00.4-0.4-0.30.3-0.2-0.30.30.0-0.20.6-0.10.1-0.0-0.10.1-0.1-0.1-0.20.20.10.1-0.10.1
Reaction time trials correct on left0.71.01.4-1.0-1.11.0-1.1-1.01.01.0-1.00.4-1.0-1.0-0.91.1-1.01.11.11.21.10.91.1-0.9-0.8
Reaction time trials on left0.71.01.5-1.1-1.11.0-1.1-1.01.01.0-1.00.4-1.0-1.0-0.91.1-1.01.11.11.21.10.91.1-0.9-0.8
Reaction time mean0.20.31.8-1.2-0.91.0-0.4-0.40.20.3-0.21.3-0.1-0.4-0.10.3-0.30.30.30.10.2-0.10.10.00.3
Reaction time mean AUC0.30.41.7-1.2-1.01.0-0.5-0.60.30.4-0.41.3-0.3-0.5-0.30.4-0.40.40.40.20.30.10.2-0.10.1
Median of all reaction times0.50.63.8-1.8-1.41.5-0.7-0.60.30.4-0.42.0-0.2-0.6-0.20.4-0.40.40.40.20.3-0.10.10.00.4
Reaction time omissions0.81.12.3-1.5-1.31.5-1.2-1.21.11.0-1.01.4-0.9-1.0-0.90.8-0.80.80.80.80.90.90.9-0.9-0.6
Reaction time false alarm rate0.10.10.40.20.3-0.30.30.1-0.2-0.40.10.20.30.50.3-0.50.5-0.5-0.5-0.7-0.1-0.2-0.30.20.3
Reaction time premature initiation rate3.34.410.13.22.9-3.22.52.1-2.2-2.01.4-2.81.82.31.8-1.71.8-1.8-1.8-2.0-1.7-1.7-1.81.50.9
Reaction time premature initiations1.21.64.62.11.9-2.11.51.2-1.3-1.10.7-2.11.01.41.1-0.90.9-0.9-0.9-1.0-0.9-1.0-0.90.80.3
Std. dev. reaction times0.10.10.2-0.00.10.00.30.2-0.4-0.30.40.30.40.30.4-0.40.4-0.4-0.4-0.5-0.2-0.5-0.40.40.5
Reaction time trials completed0.71.01.5-1.1-1.11.0-1.1-1.01.01.0-1.00.4-1.0-1.0-0.91.1-1.01.11.11.21.10.91.1-0.9-0.8
Reaction time trials AUC0.40.61.0-0.8-0.90.8-0.8-0.80.80.8-0.70.3-0.8-0.8-0.60.8-0.80.80.81.00.90.70.9-0.7-0.6
Run reversals in cocaine runway, females0.10.10.6-0.5-0.30.6-0.2-0.10.20.10.20.80.1-0.2-0.10.0-0.00.00.00.0-0.20.1-0.00.00.2
Run reversals in cocaine runway, males0.90.91.4-0.4-0.70.4-0.8-1.00.91.0-1.0-0.4-1.1-0.9-1.11.1-1.11.11.11.11.11.01.1-1.1-1.2
Latency to leave start box in cocaine runway1.71.82.51.11.3-1.01.31.5-1.6-1.41.6-0.41.41.21.4-1.31.4-1.4-1.4-1.4-1.4-1.5-1.31.51.4
Latency to leave start box in cocaine runway, F2.12.34.20.30.7-0.21.21.5-1.6-1.61.61.21.71.21.7-1.51.7-1.7-1.7-1.7-1.8-1.9-1.51.82.1
Latency to leave start box in cocaine runway, M0.30.32.71.00.7-1.00.40.2-0.20.00.1-1.6-0.10.2-0.00.1-0.10.10.10.10.30.10.1-0.2-0.5
Std. dev. time between licks in bursts0.81.03.01.71.5-1.41.01.2-0.7-0.91.3-1.70.80.80.7-0.60.6-0.6-0.6-0.7-1.0-0.6-0.80.60.3
Total sessions with >9 infusions0.50.51.30.70.7-0.50.80.9-0.8-0.71.2-0.30.80.60.8-0.70.7-0.7-0.7-0.7-0.6-0.8-0.70.80.7
Short access day 1 total inactive lever presses4.14.57.71.21.7-1.11.92.4-2.2-2.32.80.52.31.82.3-2.22.2-2.2-2.2-2.2-2.3-2.4-2.22.42.5
Short access day 10 total inactive lever presses9.110.113.73.63.7-3.43.43.5-3.3-3.33.1-2.13.33.23.2-3.13.1-3.1-3.1-3.2-3.2-3.0-3.22.92.5
Short access day 1 total infusions0.80.82.00.30.5-0.10.81.0-0.9-0.91.40.51.10.61.0-0.90.9-0.9-0.9-0.9-0.8-1.1-0.91.11.2
Short access day 10 total infusions1.11.22.50.70.9-0.61.01.3-1.2-1.21.60.21.20.91.2-1.11.1-1.1-1.1-1.1-1.1-1.3-1.11.31.2
Short access total infusions0.50.61.70.30.5-0.20.70.9-0.8-0.81.30.30.90.50.9-0.80.8-0.8-0.8-0.7-0.7-0.9-0.70.91.0
Short access day 1 locomotion0.60.71.40.20.5-0.10.70.9-0.9-0.81.20.50.90.61.0-0.80.8-0.8-0.8-0.8-0.9-1.0-0.81.01.1
Short access day 10 total locomotion3.94.45.61.51.8-1.32.02.2-2.1-2.22.2-0.12.32.02.2-2.32.3-2.3-2.3-2.4-2.1-2.2-2.42.22.2
Short access total locomotion1.31.32.10.70.9-0.61.11.3-1.2-1.21.5-0.01.31.01.3-1.31.3-1.3-1.3-1.3-1.1-1.3-1.31.31.3
One hour access (0.3 mA shock)0.30.41.61.21.0-1.10.70.7-0.6-0.50.7-1.30.50.50.5-0.30.3-0.3-0.3-0.3-0.5-0.4-0.30.30.0
Compulsive drug intake0.60.61.2-0.4-0.60.3-0.6-0.90.80.8-1.1-0.4-0.9-0.6-0.90.8-0.80.80.80.80.70.90.8-0.9-0.9
One hour access (shock baseline)0.91.12.21.51.4-1.31.11.2-1.0-1.01.3-1.21.00.91.0-0.90.9-0.9-0.9-0.9-0.8-0.9-0.80.80.6
Social response proportion0.10.10.6-0.0-0.2-0.1-0.1-0.50.10.4-0.8-0.5-0.4-0.1-0.40.2-0.20.20.20.30.70.30.3-0.4-0.5
Social responses0.10.10.90.20.0-0.40.0-0.30.00.3-0.7-0.9-0.40.0-0.20.2-0.30.30.30.40.50.20.4-0.4-0.5
Social time0.30.41.1-0.30.00.40.30.6-0.6-0.60.70.90.60.30.7-0.80.7-0.7-0.7-0.6-0.6-0.8-0.60.81.0
Soleus weight0.92.63.51.41.6-1.31.61.8-1.7-1.81.9-0.81.71.61.6-1.71.7-1.7-1.7-1.6-1.7-1.7-1.61.71.6
Bone: stiffness0.10.20.8-0.5-0.60.3-0.3-0.50.40.5-0.4-0.4-0.5-0.5-0.40.4-0.40.40.40.30.90.40.3-0.3-0.3
Tibialis anterior weight0.00.10.10.20.2-0.30.30.2-0.2-0.30.1-0.00.20.40.2-0.40.4-0.4-0.4-0.2-0.3-0.3-0.20.30.3
Time to tail flick, vehicle, before self-admin1.11.11.71.31.3-1.31.21.2-1.1-1.10.9-0.81.11.11.0-0.91.0-1.0-1.0-1.0-1.1-1.0-1.00.90.7
Time to tail flick, vehicle, after self-admin1.11.22.11.41.4-1.41.31.1-1.2-1.00.9-1.41.01.21.1-1.00.9-0.9-0.9-0.9-1.0-1.0-0.90.90.7
Time to tail flick, test, before self-admin1.11.01.70.70.9-0.81.10.9-1.2-1.00.5-0.21.11.21.1-1.01.1-1.1-1.1-1.1-1.3-1.2-1.11.11.0
Time to tail flick, test, after self-admin2.12.22.71.41.5-1.31.61.6-1.6-1.61.1-0.61.61.61.6-1.51.5-1.5-1.5-1.5-1.4-1.6-1.51.51.4
Delta time to tail flick, vehicle, before/after SA0.60.60.8-0.7-0.80.7-0.8-0.90.80.9-0.8-0.1-0.9-0.8-0.80.8-0.80.80.80.80.90.80.8-0.8-0.8
Delta time to tail flick, test, before/after SA0.00.00.10.20.2-0.10.10.2-0.1-0.20.1-0.10.20.10.1-0.20.1-0.1-0.1-0.1-0.0-0.1-0.10.10.1
Tibia length1.33.75.8-1.8-2.21.6-1.9-2.02.02.1-1.70.2-2.1-2.2-2.12.0-2.02.02.02.02.41.91.9-1.9-1.8
Ambulatory time before self-admin0.40.41.2-1.1-1.00.9-0.8-0.60.60.5-0.50.9-0.5-0.7-0.40.5-0.40.40.40.40.60.40.4-0.3-0.1
Ambulatory time after self-admin0.30.31.3-0.20.00.10.30.4-0.6-0.50.41.10.60.50.7-0.40.5-0.5-0.5-0.5-0.3-0.7-0.50.70.9
Bone: tissue strength1.71.73.3-1.5-1.31.8-1.7-0.91.51.3-0.51.6-1.1-1.7-1.21.2-1.21.21.21.40.71.31.3-1.1-0.8
Total heroin consumption0.30.30.90.80.7-0.80.70.6-0.6-0.60.6-1.00.50.60.5-0.40.5-0.4-0.4-0.4-0.6-0.5-0.40.50.3
Bone: trabecular number0.71.11.7-0.8-0.81.0-1.1-1.01.11.0-1.10.8-1.1-0.9-1.21.1-1.11.11.11.30.61.01.2-1.1-1.0
Bone: trabecular spacing1.92.43.41.41.5-1.41.61.7-1.7-1.61.8-0.81.61.51.6-1.61.6-1.6-1.6-1.9-1.4-1.5-1.61.61.5
Bone: trabecular thickness0.20.21.80.70.4-0.60.2-0.10.10.1-0.4-1.3-0.30.2-0.20.2-0.20.20.20.50.30.20.2-0.3-0.6
Bone: trabecular tissue density1.82.63.7-1.5-1.81.3-1.5-1.71.41.7-1.50.2-1.7-1.7-1.61.8-1.81.81.81.81.91.41.6-1.5-1.4
Water consumed over 24 hours0.40.51.10.70.7-0.50.70.8-0.6-0.71.0-0.60.70.50.5-0.70.7-0.7-0.7-0.6-0.8-0.6-0.70.70.6
Number of responses in last shaping day0.00.00.2-0.3-0.20.4-0.10.1-0.0-0.10.40.50.1-0.10.1-0.20.1-0.2-0.2-0.2-0.1-0.1-0.20.10.3