Hub : Genes

Sectm1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_006247882.5 0.03 0.02 3.8e-04 0.03 0.03 0.01 0.02 3.3e-04 6.2e-04 1.9e-02 1.8e-03
2 Liver alternative TSS XM_006247882.5 0.09 0.05 9.0e-13 0.12 0.12 0.11 0.12 3.5e-13 1.0e-12 1.3e-12 4.6e-13
3 Adipose alternative TSS XM_063268790.1 0.03 0.02 5.0e-04 0.03 0.03 0.02 0.03 2.9e-04 7.5e-04 2.3e-03 4.6e-04
4 Adipose gene expression Sectm1b 0.15 0.07 1.8e-13 0.08 0.12 0.11 0.12 2.6e-09 1.1e-12 1.6e-12 1.8e-13
5 Liver gene expression Sectm1b 0.49 0.11 0.0e+00 0.38 0.48 0.48 0.48 2.2e-44 2.8e-60 4.2e-60 4.0e-60
6 Liver intron excision ratio chr10_106824382_106824680 0.08 0.04 3.6e-09 0.05 0.07 0.07 0.07 4.8e-06 1.1e-08 1.1e-08 5.9e-08
7 Liver intron excision ratio chr10_106824115_106824323 0.04 0.03 3.3e-04 0.01 0.03 0.03 0.03 1.3e-02 1.4e-04 1.9e-04 3.1e-04
8 Liver intron excision ratio chr10_106824115_106824680 0.07 0.04 4.0e-07 0.04 0.06 0.06 0.06 4.4e-05 3.0e-07 1.9e-07 3.2e-07
9 Liver mRNA stability Sectm1b 0.07 0.05 3.3e-07 0.07 0.06 0.06 0.06 2.0e-08 5.7e-07 1.7e-07 3.1e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.30.51.10.00.9-0.00.90.50.90.9-1.0-0.7
Area under the delay curve1.01.11.9-1.2-1.11.2-1.00.5-1.1-0.71.01.4
BMI with tail0.20.72.60.41.1-0.31.30.50.4-0.1-0.21.6
BMI without tail1.64.910.11.33.2-1.33.10.72.82.3-2.6-1.1
Body weight0.94.111.62.63.4-2.52.4-0.71.90.8-1.40.5
Weight adjusted by age0.81.22.21.41.5-1.41.5-0.61.10.6-0.8-0.6
Bone surface0.30.62.00.60.7-0.60.5-0.20.80.8-1.0-1.4
Bone volume0.40.71.70.50.9-0.50.70.00.90.9-1.1-1.3
Breakpoint value in progressive ratio session1.21.43.41.70.3-1.7-0.8-1.9-0.7-1.10.80.4
Number of licking bursts0.30.50.9-0.50.40.41.00.80.70.9-0.8-0.5
Context. condit. distance diff. score1.82.24.0-1.00.91.01.91.71.72.0-1.7-0.9
Locomotion velocity, session 12.42.64.60.1-1.7-0.1-2.1-1.1-2.1-2.12.01.4
Locomotion distance, session 12.02.65.1-2.1-1.72.1-0.61.7-1.1-0.71.12.3
Locomotion velocity, session 23.13.66.1-1.3-2.51.4-2.20.2-2.2-1.82.22.1
Locomotion distance, session 20.60.82.1-1.2-0.41.30.41.4-0.00.10.21.5
Locomotion velocity, session 32.02.33.9-0.3-1.70.4-1.9-0.4-2.0-1.81.91.7
Locomotion distance, session 33.23.46.2-1.2-2.21.3-1.90.5-2.2-1.82.22.5
Stereotopy head waving bouts, day 30.60.71.4-0.0-1.0-0.0-1.0-0.3-1.1-1.21.00.8
Stereotopy head waving duration, day 30.30.40.7-0.3-0.90.3-0.60.1-0.8-0.80.80.8
Locomotion velocity, session 70.40.41.0-0.7-1.00.7-0.60.6-0.6-0.20.50.4
Locomotion distance, session 71.82.35.9-2.4-1.72.3-0.52.0-0.70.00.61.2
Stereotopy head waving bouts, day 70.10.10.30.40.6-0.40.4-0.20.30.1-0.3-0.3
Stereotopy head waving duration, day 70.10.20.30.40.6-0.40.5-0.10.40.2-0.4-0.4
Locomotion velocity, session 80.91.12.6-1.6-0.41.60.51.60.10.30.11.5
Locomotion distance, session 82.53.68.3-2.10.62.02.32.91.72.1-1.50.5
Degree of sensitization distance1.61.73.1-0.31.00.21.50.71.61.8-1.7-1.6
Degree of sensitization stereotypy0.20.20.60.30.8-0.20.70.00.60.4-0.5-0.3
Conditioned locomotion3.74.27.60.52.7-0.52.60.62.72.4-2.5-1.9
Cocaine response after cond. corrected0.50.61.00.4-0.2-0.5-1.0-0.8-0.8-0.91.00.8
Cocaine response after cond. not corrected0.81.01.9-0.1-0.80.1-1.3-0.4-1.1-1.11.41.4
Cocaine response before conditioning0.70.81.6-1.2-1.11.2-0.31.3-0.4-0.00.51.1
Saline control response2.02.64.41.02.1-1.01.80.12.11.8-1.9-1.6
Bone: connectivity density0.50.81.3-0.80.30.80.91.10.91.1-1.1-0.9
Bone: cortical apparent density1.62.23.7-1.1-1.91.2-1.80.3-1.8-1.41.61.4
Bone: cortical area2.13.27.22.72.6-2.71.8-1.01.1-0.2-0.51.2
Bone: cortical porosity2.12.35.32.30.1-2.3-1.1-2.3-0.9-1.50.8-0.2
Bone: cortical porosity1.82.05.42.30.5-2.3-0.6-2.1-0.4-1.00.3-0.6
Bone: cortical thickness2.44.09.63.12.5-3.11.1-1.70.3-1.30.32.1
Bone: cortical thickness0.81.02.51.31.2-1.30.4-0.7-0.1-0.90.51.6
Bone: cortical tissue density1.72.34.2-1.2-2.01.2-1.90.3-1.9-1.41.71.2
Condit. Reinf. active minus inactive responses1.31.53.40.81.8-0.81.6-0.21.51.1-1.4-0.9
Condit. Reinf. active-inactive response ratio0.40.41.20.61.1-0.60.9-0.10.70.4-0.7-0.1
Condit. Reinf. active responses2.93.57.31.12.7-1.02.4-0.12.41.9-2.2-1.6
Condit. Reinf. inactive responses1.11.32.20.51.5-0.51.3-0.11.51.3-1.4-1.3
Incentive salience index mean1.21.52.90.61.7-0.61.60.11.51.3-1.5-1.0
Condit. Reinf. lever presses0.30.40.7-0.70.20.70.70.90.60.8-0.6-0.2
Condit. Reinf. active minus inactive responses0.30.41.90.11.4-0.10.90.10.70.3-0.50.5
Condit. Reinf. active-inactive response ratio1.01.23.71.31.9-1.30.9-1.00.90.3-0.7-0.4
Condit. Reinf. active responses0.20.30.8-0.50.90.50.60.40.50.3-0.40.5
Condit. Reinf. inactive responses0.50.71.7-1.3-0.71.3-0.40.8-0.5-0.20.40.9
Condit. Reinf. lever presses0.50.60.9-0.50.90.51.00.80.90.9-1.0-0.3
Condit. Reinf. lever reinforcers received0.30.40.9-0.71.00.70.80.60.60.5-0.60.4
Conditioned reinforcement - actives0.10.20.4-0.6-0.50.6-0.00.6-0.10.00.10.4
Conditioned reinforcement - inactives0.10.10.20.40.4-0.40.1-0.20.30.2-0.3-0.1
Conditioned locomotion0.10.10.2-0.4-0.10.40.10.50.20.3-0.4-0.2
Patch foraging indifference point 0 sec0.10.10.30.50.5-0.40.0-0.00.30.3-0.4-0.4
Patch foraging indifference point AUC0.20.30.5-0.20.50.20.60.30.60.7-0.7-0.5
Delay disc. indifference point, 0s delay0.10.10.8-0.20.00.2-0.00.2-0.2-0.30.40.9
Delay disc. indifference point, 16s delay1.41.54.5-2.1-0.92.1-0.21.6-0.40.20.31.0
Delay disc. indifference point, 2s delay0.40.50.9-0.3-0.70.3-0.9-0.2-0.8-0.80.80.8
Delay disc. indifference point, 24s delay3.23.66.3-1.1-2.51.1-2.3-0.3-2.5-2.22.01.8
Delay disc. indifference point, 4s delay0.30.30.9-0.2-0.60.2-0.50.1-0.5-0.50.80.9
Delay disc. indifference point, 8s delay0.80.91.8-0.3-0.70.3-1.2-0.5-1.2-1.21.21.3
Indifference point function ln k0.71.33.1-0.9-1.40.9-0.80.7-1.1-0.91.31.8
Indifference point function log k0.71.33.1-0.9-1.40.9-0.80.7-1.1-0.91.31.8
Patch foraging total patch changes 0 sec0.10.10.40.40.6-0.30.20.10.40.4-0.5-0.3
Patch foraging total patch changes 12 sec0.20.30.60.70.7-0.7-0.1-0.50.30.2-0.5-0.8
Patch foraging total patch changes 18 sec0.20.30.8-0.60.40.60.50.90.50.7-0.6-0.2
Patch foraging total patch changes 24 sec0.30.51.20.61.1-0.60.8-0.10.80.6-0.8-0.5
Patch foraging total patch changes 6 sec0.30.51.11.10.8-1.00.3-0.50.50.3-0.7-0.8
Patch foraging time to switch 0 sec0.20.31.0-0.5-1.00.5-0.70.2-0.7-0.40.50.1
Patch foraging water rate 0 sec0.71.54.70.82.2-0.81.5-0.11.61.2-1.2-0.4
Patch foraging water rate 12 sec0.30.51.5-0.60.60.61.00.80.60.4-0.11.2
Patch foraging water rate 18 sec0.50.82.1-0.40.80.41.41.11.00.9-0.70.5
Patch foraging water rate 24 sec1.31.84.4-0.41.80.42.11.11.71.5-1.40.1
Patch foraging water rate 6 sec0.40.53.5-0.40.30.40.30.5-0.1-0.30.51.9
Seeking ratio, delayed vs. immediate footshock0.81.02.10.71.3-0.71.40.01.31.0-1.1-0.6
Distance traveled before self-admin0.60.82.41.50.9-1.50.2-1.20.2-0.2-0.2-0.3
Distance traveled after self-admin0.91.02.30.31.0-0.31.10.31.31.5-1.2-1.3
Extensor digitorum longus weight0.41.43.2-0.80.70.81.81.71.31.4-1.2-0.1
Bone: elastic displacement0.70.82.21.51.0-1.50.7-0.70.60.1-0.6-0.6
Bone: elastic work4.15.315.63.92.6-3.90.9-2.70.8-0.5-0.7-0.8
Bone: endosteal estimation0.30.71.2-0.9-0.10.90.71.10.71.1-0.8-0.6
Bone: endosteal perimeter0.40.91.61.00.8-1.00.8-0.41.00.9-0.9-1.3
Epididymis fat weight0.62.04.50.82.0-0.82.10.61.81.5-1.4-0.2
Delta time in closed arm before/after self-admin0.80.71.9-1.20.31.20.41.40.60.9-0.30.1
Delta time in open arm before/after self-admin0.10.10.2-0.1-0.40.1-0.3-0.2-0.4-0.30.3-0.2
Diff in mean of infusions in LGA sessions0.30.30.80.8-0.1-0.8-0.3-0.9-0.1-0.10.5-0.6
Delay discount exponential model param1.51.62.51.11.4-1.11.4-0.21.51.2-1.4-1.6
Extinction: sum of active levers before priming1.11.22.5-0.1-1.30.1-1.0-0.5-1.5-1.61.41.3
Active lever presses in extinction session 64.54.48.31.3-1.4-1.3-2.2-2.1-2.5-2.92.52.2
Bone: final force2.23.59.62.53.1-2.52.1-0.91.50.3-1.00.7
Bone: final moment2.64.210.42.93.2-2.92.1-1.21.60.3-1.10.4
Food consumed during 24 hour testing period0.50.71.70.41.0-0.40.70.00.90.9-1.1-1.3
Glucose9.114.327.50.6-3.4-0.6-5.2-3.2-4.9-5.04.82.7
Heart weight0.50.71.91.30.9-1.40.5-1.00.1-0.60.00.5
Delay discount hyperbolic model param1.31.52.21.01.4-1.01.4-0.11.41.1-1.4-1.5
Intermittent access intake day 1-15 change0.51.02.61.60.7-1.6-0.2-1.40.40.3-0.4-1.1
Intermittent access intake escalation0.40.82.21.50.7-1.5-0.2-1.20.30.3-0.3-0.9
Intermittent access intake escalation 21.72.05.42.30.9-2.3-0.2-2.20.2-0.1-0.1-1.2
Intermitt. access day 1 inactive lever presses0.62.44.50.82.1-0.81.70.32.12.0-1.8-1.2
Intermitt. access day 15 inactive lever presses0.61.22.1-0.21.20.21.30.71.41.5-1.3-1.2
Intermitt. access escalation Index0.81.12.1-0.31.00.31.00.61.31.4-1.4-1.3
Intermittent access day 1 total infusions0.00.10.30.10.2-0.10.50.10.20.0-0.40.1
Intermittent access day 15 total infusions0.30.50.80.80.7-0.80.5-0.40.60.5-0.9-0.7
Intermittent access terminal intake (last 3 days)0.60.81.41.00.8-1.00.5-0.70.70.6-1.0-1.2
Intermittent access total infusions0.20.20.40.40.5-0.40.5-0.10.50.4-0.6-0.3
Intermittent access day 1 locomotion0.10.10.5-0.3-0.10.3-0.10.3-0.2-0.20.20.7
Intermittent access day 15 total locomotion0.20.30.70.80.7-0.80.1-0.50.40.2-0.5-0.5
Intermittent access total locomotion0.10.10.20.40.4-0.4-0.0-0.20.1-0.0-0.20.2
Intermittent access standard deviation1.02.13.21.1-1.0-1.1-1.8-1.6-1.7-1.81.71.1
Left kidney weight0.21.03.20.80.2-0.8-0.5-0.6-0.8-1.31.01.8
Right kidney weight0.21.04.50.40.1-0.4-0.5-0.4-1.0-1.41.12.1
Cocaine induced anxiety2.63.67.92.60.2-2.6-1.3-2.8-1.3-2.01.61.1
Post-drug Anxiety3.23.55.91.8-0.5-1.8-1.9-2.4-1.8-2.41.81.6
Baseline Anxiety0.50.61.4-1.2-0.91.2-0.80.5-0.6-0.20.20.1
Tail length2.38.915.52.83.9-2.82.9-0.83.42.8-3.2-3.1
Length with tail0.93.810.93.32.5-3.30.6-2.01.00.1-0.5-0.3
Length without tail1.24.06.52.20.2-2.2-1.4-2.5-1.6-2.52.12.2
Times rat made contact with spout2.52.910.71.91.4-1.90.2-1.70.90.7-1.5-3.3
Lifetime Intake0.00.00.10.10.1-0.10.0-0.10.00.0-0.20.1
Liver weight, left1.01.73.00.0-1.4-0.0-1.7-0.2-1.6-1.51.71.7
Liver weight, right1.11.93.61.11.9-1.11.60.41.71.5-1.6-0.9
Locomotor activity0.40.61.0-0.6-1.00.6-1.00.2-1.0-0.80.80.6
Locomotor testing distance0.81.42.5-1.6-1.61.5-0.91.1-1.1-0.61.01.1
Locomotor testing rearing0.20.51.3-1.2-0.81.1-0.30.9-0.20.30.0-0.3
Locomotion in novel chamber0.30.41.2-1.1-0.41.1-0.10.7-0.20.10.50.8
Locomotion in novel chamber post-restriction2.33.75.51.72.2-1.71.9-0.72.21.9-2.2-2.3
Fecal boli incidents, locomotor time 10.20.30.8-0.9-0.50.9-0.00.9-0.10.1-0.2-0.2
Change in fecal boli incidents, locomotor task2.32.34.90.5-1.6-0.5-2.2-1.6-1.8-1.81.80.6
Time >=10cm from walls, locomotor time 11.71.93.3-0.51.50.51.61.01.61.8-1.8-1.2
Bouts of movement, locomotor time 10.91.13.3-0.6-1.80.6-1.10.1-1.3-1.11.00.7
Total resting periods, locomotor time 11.21.33.9-0.4-2.00.4-1.3-0.0-1.5-1.31.10.7
Rest time, locomotor task time 10.50.71.50.6-1.2-0.6-1.1-0.8-0.9-0.90.6-0.2
Distance moved, locomotor task time 10.10.20.7-0.00.90.00.40.00.40.5-0.10.3
Vertical activity count, locomotor time 10.30.71.4-0.21.10.21.20.51.11.1-0.8-0.3
Time >=10cm from walls, locomotor time 20.10.10.40.10.5-0.10.60.10.30.1-0.40.2
Bouts of movement, locomotor time 20.61.02.1-1.0-1.01.0-0.80.6-0.8-0.51.21.5
Total resting periods, locomotor time 20.40.61.3-1.1-0.71.1-0.30.9-0.3-0.00.71.1
Rest time, locomotor task time 20.10.10.6-0.0-0.60.00.00.10.20.4-0.2-0.8
Distance moved, locomotor task time 20.20.21.3-0.10.20.10.00.0-0.3-0.40.51.1
Vertical activity count, locomotor time 20.20.31.0-0.60.40.60.50.80.10.00.01.0
Light reinforcement 11.12.74.9-0.51.50.52.21.22.02.2-2.0-1.6
Light reinforcement 21.11.73.60.41.5-0.41.90.51.71.5-1.5-1.0
Bone: marrow area0.30.61.1-0.9-0.10.90.71.00.71.0-0.7-0.5
Bone: maximum diameter0.40.82.01.41.1-1.41.0-0.50.6-0.0-0.30.5
Bone: maximum force2.13.710.82.33.3-2.32.4-0.71.80.6-1.30.6
Bone: maximum moment2.44.211.32.73.4-2.72.3-1.11.80.5-1.30.3
Mean time between licks in bursts0.61.42.8-1.1-1.71.1-1.10.7-1.2-0.81.21.4
Mean num. licks in bursts0.61.02.21.40.5-1.4-0.5-1.50.1-0.2-0.2-1.5
Cd content in liver0.60.61.8-1.1-0.31.10.51.30.30.7-0.40.3
Co content in liver0.10.20.80.50.1-0.5-0.0-0.00.10.2-0.4-0.9
Cu content in liver0.91.13.31.80.7-1.8-0.2-1.30.2-0.1-0.3-1.1
Fe content in liver0.30.41.1-0.7-1.10.7-0.20.9-0.40.00.30.3
K content in liver2.32.24.5-0.31.20.31.81.31.82.1-1.9-1.4
Mg content in liver2.93.05.5-1.30.81.31.92.11.82.3-2.0-1.3
Mn content in liver0.00.00.2-0.10.20.10.40.20.20.1-0.20.3
Na content in liver0.20.20.7-0.6-0.20.60.30.90.30.6-0.3-0.0
Rb content in liver2.42.75.1-0.11.80.12.31.02.12.0-2.2-1.4
Se content in liver0.70.82.20.10.8-0.10.80.21.01.1-1.2-1.5
Sr content in liver1.10.91.90.7-0.5-0.7-1.1-1.4-1.0-1.21.10.3
Zn content in liver1.61.83.00.61.5-0.61.30.21.61.6-1.7-1.7
Bone: minimum diameter1.32.45.52.32.0-2.31.5-0.91.40.7-1.1-0.7
Time in familiar zone, hab. session 10.20.20.50.3-0.0-0.3-0.5-0.7-0.4-0.60.40.3
Time in novel zone, hab. session 10.10.10.3-0.20.00.20.40.50.30.4-0.3-0.3
Total zone transitions, hab. session 10.30.41.2-0.8-0.60.8-0.00.6-0.4-0.40.51.1
Total locomotion distance, hab. session 10.20.30.7-0.40.20.40.80.80.40.4-0.30.4
Locomotion velocity, hab. session 10.20.30.8-0.40.20.40.90.90.50.4-0.40.4
Time in familiar zone, hab. session 20.10.20.4-0.6-0.50.6-0.20.4-0.3-0.10.20.3
Time in novel zone, hab. session 20.10.10.3-0.1-0.10.2-0.00.1-0.1-0.20.20.5
Total zone transitions, hab. session 21.31.64.4-1.70.21.71.32.10.91.1-0.90.5
Total locomotion distance, hab. session 21.72.34.3-1.21.01.22.12.01.71.8-1.5-0.1
Locomotion velocity, hab. session 21.72.34.8-0.91.20.92.21.91.81.8-1.7-0.2
Novel to familiar place preference ratio1.61.74.52.11.6-2.10.4-1.70.6-0.1-0.4-0.8
Novelty place preference1.61.74.52.11.5-2.10.3-1.80.5-0.2-0.4-0.8
Time in novel zone, NPP test1.21.33.31.81.4-1.80.4-1.50.5-0.1-0.4-0.7
Total zone transitions, NPP test1.72.46.7-2.1-0.12.21.32.60.91.4-0.90.6
Total locomotion distance, NPP test2.12.96.5-1.80.71.82.02.61.51.9-1.50.1
Locomotion velocity, NPP test1.52.14.3-1.30.81.31.92.11.51.7-1.5-0.1
Intraocular pressure0.81.22.30.21.5-0.31.20.21.51.4-1.3-1.0
Delta distance traveled before/after self-admin0.50.51.1-1.0-0.51.00.21.00.30.8-0.2-0.4
Delta ambulatory time before/after self-admin0.91.12.7-1.7-1.01.7-0.01.40.20.9-0.1-0.4
Parametrial fat weight0.71.62.80.41.5-0.41.40.51.51.5-1.7-1.5
Pavlov. Cond. lever latency1.11.43.8-1.9-0.51.90.41.90.20.7-0.20.7
Pavlov. Cond. magazine entry latency1.62.15.62.41.5-2.3-0.1-2.10.3-0.4-0.1-0.7
Pavlov. Cond. change in total contacts1.31.43.11.6-0.0-1.6-1.0-1.8-0.8-1.20.90.1
Pavlov. Cond. index score1.72.25.62.41.7-2.30.5-1.80.80.1-0.6-1.1
Pavlov. Cond. latency score1.62.05.52.31.4-2.30.2-1.90.5-0.1-0.4-1.1
Pavlov. Cond. lever contacts0.50.61.81.40.5-1.30.1-1.10.2-0.2-0.1-0.6
Pavlov. Cond. magazine entry number2.43.08.1-2.9-1.32.80.52.70.10.8-0.20.7
Pavlov. Cond. intertrial magazine entries0.91.11.9-0.60.80.61.41.01.21.3-1.3-0.6
Pavlov. Cond. lever-magazine prob. diff.1.62.05.42.31.6-2.30.4-1.70.70.1-0.5-0.9
Pavlov. Cond. response bias1.72.15.92.41.0-2.4-0.4-2.3-0.1-0.80.2-0.5
Pavlov. Cond. lever latency1.52.03.40.3-1.6-0.3-1.8-0.9-1.7-1.81.91.3
Pavlov. Cond. magazine entry latency1.01.23.3-1.8-1.01.8-0.31.7-0.30.20.20.6
Pavlov. Cond. change in total contacts0.30.41.1-1.10.21.10.41.00.30.6-0.4-0.0
Pavlov. Cond. index score0.30.51.1-0.90.20.90.51.00.40.7-0.6-0.2
Pavlov. Cond. latency score0.50.71.5-1.00.31.00.61.20.60.9-0.8-0.3
Pavlov. Cond. lever contacts1.31.83.1-0.41.40.51.61.01.61.7-1.8-1.4
Pavlov. Cond. magazine entry number0.70.92.41.60.7-1.60.2-1.40.3-0.3-0.2-0.6
Pavlov. Cond. intertrial magazine entries0.91.42.60.61.6-0.61.6-0.11.51.2-1.5-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.41.1-1.0-0.01.00.21.00.20.5-0.4-0.1
Pavlov. Cond. response bias0.40.60.9-0.80.60.90.81.00.70.9-0.8-0.3
Time in closed arm before self-admin0.60.81.70.6-0.8-0.6-0.9-0.9-1.0-1.30.90.6
Time in closed arm after self-admin0.80.82.00.2-0.9-0.2-1.4-0.8-1.1-1.01.10.6
Time in open arm before self-admin1.01.02.0-1.00.61.01.11.41.01.2-1.0-0.4
Time in open arm after self-admin0.20.20.6-0.70.10.70.40.70.20.3-0.30.1
Bone: periosteal estimation0.51.12.61.31.6-1.31.5-0.21.10.5-0.80.3
Bone: periosteal perimeter1.73.09.13.01.8-3.00.6-2.10.5-0.5-0.2-0.2
Bone: post-yield work0.10.10.4-0.50.10.50.30.50.10.10.00.6
Progressive ratio test 1 active lever presses0.10.10.30.40.5-0.40.2-0.10.40.4-0.5-0.3
Progressive ratio test 1 breakpoint0.20.20.40.50.6-0.50.3-0.20.40.4-0.6-0.4
Progressive ratio test 1 inactive lever presses1.82.54.30.62.0-0.62.00.52.11.9-2.0-1.4
Progressive ratio test 2 active lever presses0.20.20.50.20.7-0.20.30.00.60.6-0.7-0.4
Progressive ratio test 2 breakpoint0.20.20.50.30.7-0.30.3-0.00.60.6-0.6-0.4
Progressive ratio test 2 inactive lever presses0.10.20.50.70.5-0.7-0.1-0.60.1-0.1-0.00.1
Incentive Sensitization - Responses0.40.61.30.20.9-0.20.60.10.90.9-1.1-1.0
Incentive Sensitization - Breakpoint0.40.51.00.20.8-0.20.40.00.80.8-1.0-0.9
Sum of active levers in priming session hrs 5-61.21.13.11.60.4-1.6-0.5-1.8-0.4-0.80.3-0.3
Progressive ratio0.40.61.0-0.7-0.90.7-0.80.3-1.0-0.90.70.9
Food seeking constrained by brief footshock0.40.51.10.7-0.5-0.7-0.7-1.0-0.7-0.80.4-0.5
Seeking ratio, punishment vs. effort0.20.20.40.10.4-0.10.60.10.60.7-0.6-0.6
Retroperitoneal fat weight1.98.113.71.63.7-1.63.60.53.63.2-3.4-2.4
Reaction time number correct2.44.59.6-2.50.72.52.33.11.92.4-1.9-0.2
Reaction time mean minus median0.20.60.90.5-0.9-0.5-0.8-1.0-0.8-0.80.8-0.1
Reaction time mean minus median AUC0.00.10.20.2-0.4-0.2-0.1-0.4-0.2-0.20.3-0.1
Reaction time num false alarms0.10.10.2-0.3-0.40.3-0.40.1-0.3-0.20.0-0.3
Reaction time num false alarms AUC0.20.30.6-0.7-0.80.7-0.40.5-0.4-0.20.2-0.0
Reaction time trials correct on left2.44.59.6-2.50.72.52.33.11.92.4-1.9-0.2
Reaction time trials on left2.54.710.0-2.60.72.52.43.21.92.4-1.9-0.2
Reaction time mean0.10.20.60.20.4-0.20.8-0.10.50.4-0.6-0.7
Reaction time mean AUC0.20.41.2-0.20.30.21.10.50.70.7-0.7-0.6
Median of all reaction times0.30.41.20.00.7-0.01.10.30.70.6-0.8-0.6
Reaction time omissions0.10.20.4-0.10.20.10.60.50.40.5-0.5-0.4
Reaction time false alarm rate0.81.12.30.6-1.0-0.6-1.5-1.2-1.3-1.31.0-0.1
Reaction time premature initiation rate0.50.71.4-0.9-1.20.9-1.10.2-0.9-0.60.80.5
Reaction time premature initiations0.81.54.3-2.1-0.62.10.31.90.30.8-0.40.2
Std. dev. reaction times0.10.20.8-0.5-0.90.5-0.20.1-0.5-0.30.4-0.0
Reaction time trials completed2.54.710.0-2.60.72.52.43.21.92.4-1.9-0.2
Reaction time trials AUC2.54.79.9-2.60.72.52.43.11.92.4-1.9-0.3
Run reversals in cocaine runway, females0.60.61.8-1.3-0.41.30.21.10.10.4-0.4-0.2
Run reversals in cocaine runway, males1.21.33.31.81.0-1.80.1-1.60.50.1-0.3-1.0
Latency to leave start box in cocaine runway0.20.30.8-0.8-0.40.80.00.90.00.3-0.0-0.1
Latency to leave start box in cocaine runway, F1.31.54.3-1.7-0.31.71.02.10.71.1-0.6-0.1
Latency to leave start box in cocaine runway, M0.30.30.70.6-0.0-0.6-0.8-0.8-0.5-0.60.4-0.1
Std. dev. time between licks in bursts2.02.75.4-1.50.91.52.12.31.72.0-1.50.2
Total sessions with >9 infusions0.30.30.6-0.4-0.80.4-0.60.1-0.8-0.60.30.8
Short access day 1 total inactive lever presses0.30.41.1-0.8-0.00.80.21.00.10.20.11.1
Short access day 10 total inactive lever presses1.02.45.71.02.4-1.01.70.12.01.8-1.7-1.1
Short access day 1 total infusions1.11.52.5-1.1-1.61.1-1.10.5-1.4-1.21.11.5
Short access day 10 total infusions0.81.01.71.30.9-1.30.5-0.90.70.5-1.1-1.3
Short access total infusions0.10.10.2-0.0-0.30.0-0.4-0.2-0.4-0.40.20.3
Short access day 1 locomotion0.60.81.80.2-0.8-0.2-0.9-0.6-1.2-1.30.91.1
Short access day 10 total locomotion0.61.01.81.0-0.6-1.0-1.2-1.3-1.1-1.30.90.2
Short access total locomotion0.70.91.50.8-0.5-0.8-1.0-1.1-1.1-1.20.90.7
One hour access (0.3 mA shock)0.40.51.00.10.7-0.10.70.30.80.9-1.0-0.9
Compulsive drug intake1.11.32.5-0.41.10.41.41.01.51.6-1.2-1.0
One hour access (shock baseline)0.10.10.5-0.10.10.10.30.20.30.4-0.7-0.5
Social response proportion0.40.41.3-0.9-0.20.9-0.50.6-0.5-0.30.51.1
Social responses0.30.41.8-0.6-0.30.6-0.30.8-0.5-0.30.51.3
Social time0.20.31.4-0.5-0.40.5-0.10.7-0.4-0.40.41.2
Soleus weight1.03.14.51.42.1-1.42.0-0.32.01.6-2.0-2.1
Bone: stiffness0.40.74.00.31.1-0.30.90.20.2-0.40.22.0
Tibialis anterior weight0.10.50.9-0.30.20.30.90.80.80.8-0.9-0.6
Time to tail flick, vehicle, before self-admin0.10.10.2-0.4-0.30.4-0.10.2-0.2-0.1-0.0-0.2
Time to tail flick, vehicle, after self-admin1.41.82.9-1.4-1.71.4-1.11.0-1.2-0.91.51.6
Time to tail flick, test, before self-admin0.10.10.50.0-0.2-0.0-0.7-0.2-0.2-0.10.20.3
Time to tail flick, test, after self-admin1.41.53.2-0.0-1.20.0-1.8-0.6-1.5-1.31.51.3
Delta time to tail flick, vehicle, before/after SA0.30.30.8-0.7-0.30.70.20.90.30.50.00.1
Delta time to tail flick, test, before/after SA1.21.22.40.2-0.9-0.2-1.2-0.8-1.4-1.51.41.3
Tibia length4.111.425.45.04.9-5.02.7-3.12.50.6-2.0-1.2
Ambulatory time before self-admin1.01.53.81.91.7-1.90.8-1.30.70.1-0.6-0.4
Ambulatory time after self-admin0.30.40.80.30.7-0.30.80.10.80.9-0.7-0.6
Bone: tissue strength1.01.12.70.61.5-0.61.60.61.20.9-1.1-0.0
Total heroin consumption1.51.83.21.0-0.7-1.0-0.9-1.5-1.4-1.81.71.5
Bone: trabecular number0.10.20.80.10.5-0.10.1-0.10.30.3-0.5-0.9
Bone: trabecular spacing1.62.15.1-1.50.51.51.82.31.41.7-1.20.3
Bone: trabecular thickness1.41.74.52.00.8-2.0-0.7-2.1-0.2-0.70.1-1.1
Bone: trabecular tissue density0.50.81.4-1.0-1.21.0-0.70.5-0.9-0.70.81.0
Water consumed over 24 hours0.30.40.90.8-0.1-0.8-0.8-1.0-0.4-0.50.2-0.9
Number of responses in last shaping day0.40.42.1-0.2-0.30.2-0.50.1-0.7-0.80.61.4