Sdhb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	RMTg	gene expression	Sdhb	0.21	0.11	4.8e-03	0.13	0.1	0.11	0.11	2.5e-04	1.5e-03	6.1e-04	7.2e-04
2	Liver	gene expression	Sdhb	0.15	0.08	1.7e-10	0.1	0.09	0.09	0.09	6.6e-11	1.0e-09	6.7e-10	2.4e-10
3	PL	gene expression	Sdhb	0.1	0.07	4.7e-03	0.03	0.02	0.04	0.03	2.4e-04	3.1e-03	4.1e-05	5.5e-04
4	pVTA	gene expression	Sdhb	0.23	0.1	1.1e-06	0.15	0.15	0.09	0.15	4.9e-07	5.3e-07	1.3e-04	5.2e-07
5	LHb	gene expression	Sdhb	0.3	0.13	3.2e-04	0.11	0.04	0.07	0.07	1.8e-03	4.2e-02	7.7e-03	1.1e-02
6	NAcc	gene expression	Sdhb	0.08	0.04	1.9e-06	0.05	0.05	0.05	0.05	7.6e-07	6.8e-07	3.0e-06	1.3e-06
7	Adipose	gene expression	Sdhb	0.14	0.08	4.7e-13	0.12	0.11	0.12	0.12	7.7e-13	4.5e-12	1.4e-13	2.4e-13
8	Adipose	mRNA stability	Sdhb	0.04	0.03	2.0e-05	0.03	0.04	0.04	0.04	2.3e-04	3.4e-05	2.8e-05	4.4e-05
9	Brain	gene expression	Sdhb	0.07	0.04	5.3e-06	0.04	0.04	0.04	0.05	2.7e-04	9.4e-05	6.8e-05	2.7e-05
10	BLA	gene expression	Sdhb	0.08	0.05	4.6e-04	0	0.03	0	0.01	1.9e-01	1.6e-02	1.8e-01	1.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.5	0.9	1.7	1.3	1.2	0.9	1.1	1.2	-0.9	0.5	1.0	-0.5	0.0
Area under the delay curve	0.3	0.3	0.6	0.8	0.5	0.7	0.4	0.3	0.7	0.6	0.8	-0.3	-0.1
BMI with tail	0.9	3.0	5.2	-1.5	-1.6	-2.3	-1.7	-1.2	1.4	-2.1	-2.1	1.9	1.1
BMI without tail	2.3	4.8	8.0	-2.7	-2.8	-1.4	-2.8	-2.2	2.6	-1.8	-1.9	1.9	1.1
Body weight	0.5	2.0	4.4	-0.9	-1.0	-1.3	-1.2	-0.1	0.9	-2.1	-1.8	2.1	1.6
Weight adjusted by age	1.3	1.4	3.4	-1.0	-0.9	-1.8	-0.9	-1.4	0.9	-1.1	-1.0	0.9	1.6
Bone surface	0.6	1.1	2.0	1.4	1.4	1.2	1.3	1.0	-1.1	0.5	1.0	-0.5	0.5
Bone volume	0.7	1.1	2.7	1.3	1.3	1.6	1.2	1.0	-0.8	0.7	1.1	-0.4	0.3
Breakpoint value in progressive ratio session	0.1	0.1	0.6	-0.1	-0.2	0.2	-0.4	-0.8	0.4	0.1	-0.2	0.1	0.2
Number of licking bursts	0.9	1.1	2.3	0.9	0.9	1.5	0.9	0.5	-1.0	1.1	1.2	-1.2	-1.0
Context. condit. distance diff. score	1.0	1.2	5.0	0.8	0.8	2.2	0.8	0.9	-1.3	0.8	1.0	-0.7	-1.1
Locomotion velocity, session 1	1.2	1.2	3.2	0.4	0.3	1.6	0.3	0.4	-0.3	1.5	1.6	-1.1	-1.8
Locomotion distance, session 1	1.8	2.3	5.4	0.9	0.9	1.8	0.8	1.1	-0.2	2.3	1.9	-1.7	-2.2
Locomotion velocity, session 2	0.8	0.9	2.9	0.2	0.2	1.4	0.2	0.4	0.1	1.3	1.1	-1.1	-1.7
Locomotion distance, session 2	0.4	0.5	2.4	-0.9	-0.8	0.4	-0.9	-0.3	1.5	0.1	-0.2	0.3	-0.6
Locomotion velocity, session 3	0.2	0.2	0.7	0.3	0.5	-0.2	0.4	0.7	-0.5	0.1	0.2	-0.2	-0.8
Locomotion distance, session 3	0.2	0.2	0.9	0.1	0.2	0.9	0.1	0.1	-0.5	0.4	0.4	-0.2	-0.3
Stereotopy head waving bouts, day 3	0.2	0.2	1.1	-0.3	-0.3	-0.4	-0.4	-0.2	1.1	0.4	-0.1	0.1	-0.4
Stereotopy head waving duration, day 3	0.2	0.2	1.0	0.1	0.1	-0.8	0.0	0.3	0.5	0.5	0.2	-0.4	-1.0
Locomotion velocity, session 7	0.4	0.4	2.4	0.7	0.8	0.3	0.7	0.0	-1.6	-0.1	-0.1	-0.2	0.2
Locomotion distance, session 7	0.4	0.4	1.5	0.5	0.6	1.2	0.6	-0.2	-0.9	0.6	0.6	-0.6	0.2
Stereotopy head waving bouts, day 7	0.7	0.8	1.1	0.9	1.0	-0.3	0.9	1.0	-0.7	0.9	0.8	-0.8	-1.0
Stereotopy head waving duration, day 7	0.7	0.9	1.9	0.9	0.9	0.1	0.9	1.1	-0.7	1.1	1.0	-0.8	-1.4
Locomotion velocity, session 8	0.6	0.8	4.1	-0.8	-0.8	2.0	-0.9	-0.7	0.8	-0.1	-0.1	0.4	-0.3
Locomotion distance, session 8	0.7	1.0	5.0	0.6	0.7	2.2	0.6	1.0	-0.6	0.8	0.8	-0.4	-1.0
Degree of sensitization distance	0.3	0.3	1.0	-0.3	-0.4	-0.5	-0.3	-1.0	0.4	-0.3	-0.4	0.1	0.8
Degree of sensitization stereotypy	0.5	0.5	1.2	0.8	0.9	-0.6	0.9	1.1	-0.9	0.3	0.4	-0.4	-0.5
Conditioned locomotion	1.0	1.2	1.9	1.2	1.3	0.9	1.3	1.4	-0.8	1.1	0.7	-1.1	-1.0
Cocaine response after cond. corrected	7.9	8.8	17.9	-2.9	-2.8	-4.2	-2.9	-3.4	2.8	-2.6	-3.0	2.5	2.2
Cocaine response after cond. not corrected	4.4	4.8	11.6	-1.9	-1.8	-3.4	-2.0	-2.7	1.8	-2.0	-2.2	1.8	1.8
Cocaine response before conditioning	4.2	5.1	6.2	2.4	2.3	2.5	2.3	2.1	-2.2	2.1	2.4	-2.2	-1.9
Saline control response	1.3	1.7	3.9	1.7	1.6	0.5	1.5	2.0	-1.6	0.7	0.9	-1.0	-0.3
Bone: connectivity density	0.4	0.7	1.4	1.2	1.2	-0.4	1.1	1.0	-1.0	0.2	0.7	-0.5	0.2
Bone: cortical apparent density	0.9	1.1	2.0	1.1	1.1	-1.4	0.9	0.9	-1.0	0.6	0.8	-1.4	-1.2
Bone: cortical area	1.9	2.9	4.5	2.1	2.1	1.6	2.0	2.0	-1.7	1.5	1.5	-1.2	-0.7
Bone: cortical porosity	1.4	1.5	3.6	1.1	1.1	0.4	1.2	0.8	-0.1	1.9	1.7	-1.8	-0.9
Bone: cortical porosity	0.3	0.3	1.4	-0.4	-0.3	-0.6	-0.3	-0.4	1.2	0.8	0.5	-0.5	-0.3
Bone: cortical thickness	4.4	7.3	11.2	3.4	3.3	0.8	3.2	3.2	-2.8	2.5	2.4	-2.4	-1.9
Bone: cortical thickness	2.7	3.1	5.0	2.2	2.2	1.9	2.2	1.9	-1.7	1.5	1.5	-1.3	-0.4
Bone: cortical tissue density	0.7	0.9	2.2	1.0	0.9	-1.5	0.8	0.7	-0.8	0.5	0.6	-1.3	-1.0
Condit. Reinf. active minus inactive responses	0.5	0.5	1.9	0.2	0.3	0.8	0.2	-0.1	0.3	1.4	1.0	-0.9	-0.9
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.5	-0.4	-0.3	-0.2	-0.3	-0.0	0.7	0.7	0.6	-0.3	-0.6
Condit. Reinf. active responses	0.9	1.1	3.0	0.7	0.8	1.3	0.7	0.2	-0.3	1.7	1.2	-1.2	-1.2
Condit. Reinf. inactive responses	0.2	0.3	0.9	0.6	0.6	0.9	0.5	-0.2	-0.5	0.7	0.2	-0.3	-0.3
Incentive salience index mean	1.2	1.5	3.9	0.7	0.8	1.2	0.7	0.5	-0.1	2.0	1.7	-1.5	-1.5
Condit. Reinf. lever presses	1.3	1.8	3.3	1.0	1.1	1.4	1.0	1.0	-0.6	1.8	1.8	-1.5	-1.6
Condit. Reinf. active minus inactive responses	0.3	0.3	0.8	-0.5	-0.4	-0.6	-0.5	-0.0	0.0	-0.9	-0.7	0.8	0.5
Condit. Reinf. active-inactive response ratio	0.5	0.5	1.3	-0.6	-0.6	-1.2	-0.7	-0.6	0.5	-0.9	-0.8	0.7	0.4
Condit. Reinf. active responses	0.3	0.4	1.8	0.3	0.4	1.3	0.3	0.8	-0.6	0.0	0.5	-0.1	-0.1
Condit. Reinf. inactive responses	2.2	2.7	7.2	1.4	1.5	2.7	1.5	1.7	-1.2	1.5	1.9	-1.5	-1.0
Condit. Reinf. lever presses	0.4	0.5	3.2	0.3	0.3	1.8	0.3	0.4	-0.4	0.5	0.8	-0.4	0.1
Condit. Reinf. lever reinforcers received	0.1	0.2	0.8	-0.0	0.0	0.9	-0.1	0.5	-0.4	-0.5	0.0	0.3	0.4
Conditioned reinforcement - actives	0.2	0.2	0.6	0.2	0.3	-0.2	0.3	0.3	-0.2	0.6	0.4	-0.5	-0.8
Conditioned reinforcement - inactives	0.1	0.1	0.3	0.2	0.2	0.0	0.2	0.6	-0.5	-0.1	-0.1	-0.0	-0.6
Conditioned locomotion	0.2	0.2	0.3	-0.5	-0.4	-0.6	-0.4	-0.6	0.5	0.5	0.4	-0.4	-0.4
Patch foraging indifference point 0 sec	4.4	7.1	13.7	3.3	3.3	0.2	3.0	3.7	-2.9	2.0	2.0	-2.5	-2.0
Patch foraging indifference point AUC	3.3	3.8	6.5	2.1	2.1	2.4	2.3	1.3	-2.5	1.6	2.0	-1.7	-0.4
Delay disc. indifference point, 0s delay	0.5	0.5	1.6	0.5	0.2	1.3	0.1	0.1	1.0	0.8	1.0	-0.3	-0.6
Delay disc. indifference point, 16s delay	0.1	0.1	0.8	0.2	-0.0	0.5	-0.2	-0.1	0.9	0.3	0.2	0.2	0.0
Delay disc. indifference point, 2s delay	0.3	0.4	1.2	1.1	1.0	0.4	0.7	0.5	0.1	0.3	0.5	-0.2	0.6
Delay disc. indifference point, 24s delay	0.5	0.5	0.8	0.6	0.6	0.9	0.9	0.8	-0.3	0.7	0.7	-0.7	-0.4
Delay disc. indifference point, 4s delay	0.2	0.2	1.0	0.2	-0.2	-0.9	-0.3	-0.2	1.0	-0.3	-0.1	0.4	0.4
Delay disc. indifference point, 8s delay	0.2	0.2	1.6	0.0	-0.1	0.0	-0.2	-0.4	1.3	0.2	0.3	0.1	0.2
Indifference point function ln k	2.6	3.6	7.7	-2.4	-2.2	-2.4	-2.3	-1.5	2.8	-1.1	-1.5	1.2	0.0
Indifference point function log k	2.6	3.6	7.7	-2.4	-2.2	-2.4	-2.3	-1.5	2.8	-1.1	-1.5	1.2	0.0
Patch foraging total patch changes 0 sec	3.9	6.3	12.1	3.1	3.0	0.1	2.8	3.5	-2.7	2.0	2.0	-2.4	-1.9
Patch foraging total patch changes 12 sec	7.2	9.3	13.4	3.7	3.6	2.2	3.5	3.6	-3.5	2.5	2.8	-2.7	-1.7
Patch foraging total patch changes 18 sec	14.7	18.9	27.6	5.3	5.1	3.4	5.0	4.7	-5.2	3.7	3.8	-4.0	-2.3
Patch foraging total patch changes 24 sec	6.2	7.6	11.8	3.3	3.4	2.0	3.4	3.2	-3.3	2.0	2.6	-2.4	-0.7
Patch foraging total patch changes 6 sec	5.9	8.8	13.6	3.4	3.6	1.4	3.6	3.4	-3.7	2.3	2.7	-2.9	-1.4
Patch foraging time to switch 0 sec	0.2	0.2	0.9	-0.0	0.0	-0.6	-0.2	-0.3	-0.0	-0.9	-0.7	0.6	0.6
Patch foraging water rate 0 sec	1.4	2.2	3.7	1.6	1.4	1.0	1.4	1.3	-1.2	1.9	1.7	-1.7	-1.3
Patch foraging water rate 12 sec	0.2	0.3	0.9	0.8	0.5	0.0	0.3	1.0	-0.2	0.6	0.5	-0.3	-0.8
Patch foraging water rate 18 sec	1.0	1.3	3.1	-1.7	-1.7	-0.9	-1.6	-0.7	1.8	-0.1	-0.4	0.6	-0.1
Patch foraging water rate 24 sec	0.2	0.3	0.8	-0.6	-0.7	0.5	-0.7	-0.9	0.5	0.1	-0.3	0.2	0.1
Patch foraging water rate 6 sec	0.6	0.8	1.6	1.1	1.1	0.1	1.0	1.0	-0.6	1.3	1.0	-1.0	-0.7
Seeking ratio, delayed vs. immediate footshock	1.3	1.4	2.5	-1.3	-1.5	-0.3	-1.5	-0.9	1.4	-1.1	-1.1	1.6	0.8
Distance traveled before self-admin	1.8	2.0	2.7	1.6	1.5	1.0	1.4	0.9	-1.4	1.6	1.6	-1.4	-1.4
Distance traveled after self-admin	1.8	2.1	3.0	1.5	1.5	0.5	1.7	1.2	-1.7	1.6	1.4	-1.6	-1.3
Extensor digitorum longus weight	0.0	0.1	0.2	-0.3	-0.2	0.4	-0.2	0.5	0.0	0.0	0.0	0.0	-0.4
Bone: elastic displacement	3.6	4.1	5.9	2.4	2.4	0.4	2.4	1.7	-2.4	1.9	1.9	-2.4	-1.3
Bone: elastic work	4.7	6.0	8.2	2.8	2.9	2.0	2.8	2.2	-2.7	2.6	2.3	-2.5	-1.2
Bone: endosteal estimation	2.8	6.0	8.8	-2.6	-2.7	0.2	-2.6	-2.5	2.3	-2.4	-2.3	3.0	2.7
Bone: endosteal perimeter	1.7	3.6	5.3	-2.2	-2.2	0.2	-2.1	-1.9	2.0	-1.7	-1.9	2.3	1.6
Epididymis fat weight	2.6	6.0	12.0	-2.1	-2.2	-1.8	-2.3	-1.7	1.7	-3.1	-3.1	3.5	2.1
Delta time in closed arm before/after self-admin	5.1	5.0	7.2	-2.2	-2.4	-0.9	-2.6	-2.0	2.6	-2.2	-2.0	2.7	2.1
Delta time in open arm before/after self-admin	0.4	0.4	0.7	-0.7	-0.7	-0.9	-0.7	-0.8	0.7	-0.1	-0.4	0.2	-0.6
Diff in mean of infusions in LGA sessions	0.2	0.2	1.3	0.1	0.2	0.5	0.1	-0.2	-0.3	-0.5	-0.5	0.3	1.1
Delay discount exponential model param	0.2	0.2	0.5	-0.6	-0.4	-0.3	-0.3	-0.3	-0.7	-0.4	-0.5	0.1	-0.1
Extinction: sum of active levers before priming	1.1	1.1	2.7	0.6	0.5	-0.2	0.1	-0.2	1.0	1.7	1.6	-1.6	-1.2
Active lever presses in extinction session 6	0.4	0.4	1.4	-0.6	-0.6	0.8	-0.5	-1.2	1.0	-0.1	-0.1	0.1	0.6
Bone: final force	1.1	1.7	2.8	1.6	1.5	1.7	1.6	1.4	-1.4	1.3	1.1	-0.7	0.2
Bone: final moment	0.9	1.4	2.9	1.4	1.4	1.7	1.4	1.2	-1.2	1.2	1.0	-0.5	0.1
Food consumed during 24 hour testing period	0.9	1.0	1.7	-1.2	-1.2	-0.9	-1.2	-0.5	0.7	-1.3	-0.9	1.0	1.0
Glucose	0.4	0.5	0.7	0.8	0.8	-0.5	0.7	0.7	-0.8	0.9	0.6	-0.7	-0.8
Heart weight	3.4	4.8	9.2	3.0	2.8	0.7	2.6	2.5	-2.8	1.5	1.9	-1.6	-0.9
Delay discount hyperbolic model param	0.2	0.2	0.7	-0.8	-0.6	-0.3	-0.4	-0.3	-0.6	-0.3	-0.5	0.1	-0.2
Intermittent access intake day 1-15 change	0.8	0.8	5.2	0.1	0.1	-2.3	0.1	0.3	-0.5	-1.0	-1.0	0.5	0.5
Intermittent access intake escalation	1.0	1.0	4.9	-0.0	0.0	-2.2	-0.0	-0.1	-0.3	-1.3	-1.3	0.8	0.9
Intermittent access intake escalation 2	0.5	0.5	2.8	-0.2	-0.2	-1.7	-0.2	0.0	-0.1	-1.0	-0.8	0.6	0.7
Intermitt. access day 1 inactive lever presses	0.1	0.1	0.4	-0.2	-0.1	-0.2	-0.2	0.2	-0.0	-0.6	-0.4	0.5	0.0
Intermitt. access day 15 inactive lever presses	0.0	0.0	0.2	-0.3	-0.2	-0.4	-0.1	-0.1	-0.1	-0.0	-0.0	-0.0	0.0
Intermitt. access escalation Index	0.7	0.6	1.0	0.7	0.6	0.6	0.8	0.6	-0.8	1.0	1.0	-0.7	-0.8
Intermittent access day 1 total infusions	0.6	0.7	1.5	-1.0	-1.0	0.8	-0.9	-0.6	1.2	0.7	0.6	-0.3	-0.8
Intermittent access day 15 total infusions	1.0	1.1	2.2	-1.2	-1.2	-1.5	-1.2	-1.0	1.1	-0.8	-0.9	0.7	0.3
Intermittent access terminal intake (last 3 days)	0.6	0.6	1.5	-1.1	-1.0	-1.2	-1.0	-0.3	0.7	-0.7	-0.7	0.5	0.1
Intermittent access total infusions	0.9	1.0	2.1	-1.5	-1.4	-1.0	-1.4	-1.0	1.3	-0.2	-0.3	0.3	-0.3
Intermittent access day 1 locomotion	0.2	0.2	0.5	-0.5	-0.5	0.4	-0.5	-0.2	0.5	0.4	0.3	-0.2	-0.7
Intermittent access day 15 total locomotion	0.8	0.9	2.9	-1.1	-1.1	-1.7	-1.0	-0.2	0.9	-0.8	-0.7	0.7	0.4
Intermittent access total locomotion	0.3	0.3	2.2	-0.6	-0.5	-1.5	-0.5	-0.3	0.5	-0.3	-0.3	-0.0	-0.0
Intermittent access standard deviation	0.7	0.7	1.6	-1.1	-1.1	-1.0	-1.3	-0.4	1.0	-0.3	-0.5	0.6	-0.4
Left kidney weight	0.3	0.7	2.0	1.2	0.8	0.9	0.7	1.4	-0.6	0.6	0.9	-0.2	-0.3
Right kidney weight	0.0	0.1	0.4	0.2	-0.1	-0.2	-0.3	0.6	0.3	-0.0	0.0	0.7	0.1
Cocaine induced anxiety	0.6	0.7	1.9	1.1	1.2	-0.3	1.3	0.6	-1.4	0.1	0.0	-0.4	0.5
Post-drug Anxiety	1.0	1.1	2.6	1.5	1.6	-0.0	1.6	1.1	-1.6	-0.2	0.1	-0.3	0.6
Baseline Anxiety	0.5	0.5	1.2	0.6	0.6	0.6	0.5	1.1	-0.4	0.6	0.9	-0.6	-0.9
Tail length	0.7	2.1	3.2	-1.6	-1.8	1.1	-1.8	-1.2	1.7	-1.1	-1.0	1.4	1.4
Length with tail	0.2	0.6	1.9	0.2	0.1	0.9	0.0	0.6	-0.1	-0.9	-0.7	1.1	1.4
Length without tail	0.9	2.0	5.4	1.9	2.0	0.1	1.9	2.3	-2.0	-0.0	0.3	-0.1	-0.0
Times rat made contact with spout	1.1	1.3	3.0	0.7	0.7	1.5	0.7	0.8	-0.2	1.7	1.7	-1.2	-1.1
Lifetime Intake	1.1	1.2	2.9	-1.7	-1.6	-0.5	-1.6	-1.3	1.5	0.0	-0.2	0.2	-0.5
Liver weight, left	0.1	0.2	0.6	-0.6	-0.6	-0.2	-0.6	0.6	0.7	-0.3	0.1	0.3	-0.2
Liver weight, right	0.3	0.4	1.2	0.4	0.5	-0.7	0.6	1.1	-0.8	-0.8	-0.5	0.3	0.4
Locomotor activity	2.3	3.6	9.7	2.0	2.0	-0.5	1.9	3.1	-1.9	1.6	1.5	-1.4	-2.0
Locomotor testing distance	3.7	6.2	9.2	2.2	2.3	0.3	2.3	2.7	-2.2	3.0	2.6	-3.0	-3.0
Locomotor testing rearing	3.0	4.7	7.5	1.8	1.8	0.5	1.9	2.1	-2.0	2.7	2.4	-2.6	-2.7
Locomotion in novel chamber	1.0	1.3	2.4	1.5	1.5	1.5	1.4	0.8	-1.3	0.7	0.8	-0.6	0.4
Locomotion in novel chamber post-restriction	0.8	0.9	2.5	1.6	1.4	-0.0	1.4	1.1	-1.0	0.5	0.6	-0.3	-0.4
Fecal boli incidents, locomotor time 1	1.2	1.3	6.5	-0.3	0.2	-2.6	-0.2	0.3	-0.1	-1.2	-1.5	1.2	1.1
Change in fecal boli incidents, locomotor task	0.3	0.3	1.0	-0.4	-0.4	0.8	-0.2	-1.0	0.6	0.3	0.4	-0.5	-0.4
Time >=10cm from walls, locomotor time 1	0.8	0.8	1.9	0.9	0.8	-1.4	0.6	1.1	-1.3	-0.7	-1.0	0.5	0.1
Bouts of movement, locomotor time 1	0.6	0.7	2.5	0.0	-0.1	-0.9	0.2	-0.5	-0.2	-1.2	-1.2	0.7	1.6
Total resting periods, locomotor time 1	0.7	0.8	3.4	0.1	0.1	-0.9	0.4	-0.7	-0.5	-1.2	-1.1	0.6	1.8
Rest time, locomotor task time 1	0.7	0.8	2.2	0.1	0.2	-0.9	0.1	-1.1	-0.7	-1.1	-1.1	0.6	1.5
Distance moved, locomotor task time 1	2.9	3.1	6.4	1.5	1.3	1.5	1.2	2.2	-0.8	2.1	2.1	-1.8	-2.5
Vertical activity count, locomotor time 1	2.2	2.3	5.7	1.2	0.7	1.1	0.7	2.0	-0.3	1.9	1.9	-1.6	-2.4
Time >=10cm from walls, locomotor time 2	0.2	0.2	1.4	0.2	0.2	0.0	0.6	0.3	-1.2	-0.4	-0.5	-0.1	-0.3
Bouts of movement, locomotor time 2	0.3	0.4	1.9	0.7	0.6	-1.4	0.5	0.7	-0.1	-0.0	-0.1	-0.3	0.2
Total resting periods, locomotor time 2	0.5	0.5	1.2	1.0	0.9	-1.1	0.8	0.9	-0.4	0.3	0.2	-0.5	0.0
Rest time, locomotor task time 2	0.3	0.4	0.8	0.9	0.7	-0.7	0.7	-0.2	-0.8	0.1	-0.1	-0.1	0.8
Distance moved, locomotor task time 2	0.3	0.4	0.9	0.6	0.5	0.3	0.7	0.9	-0.8	0.1	0.4	-0.5	-0.7
Vertical activity count, locomotor time 2	1.0	1.1	3.3	0.9	0.7	-0.1	0.8	1.8	-0.9	0.9	0.9	-1.0	-1.5
Light reinforcement 1	1.3	2.3	4.8	1.4	1.6	0.2	1.7	2.2	-1.7	1.3	1.6	-1.5	-1.2
Light reinforcement 2	0.4	0.5	1.3	-1.1	-0.8	-1.1	-0.7	-0.6	0.3	-0.4	-0.7	0.6	0.2
Bone: marrow area	2.8	6.0	8.8	-2.6	-2.7	0.2	-2.6	-2.6	2.3	-2.4	-2.4	3.0	2.7
Bone: maximum diameter	0.3	0.6	3.8	0.4	0.3	2.0	0.3	0.6	-0.1	0.7	0.8	-0.3	-0.2
Bone: maximum force	0.8	1.4	2.1	1.5	1.4	1.4	1.3	1.4	-1.2	1.2	1.0	-0.5	0.1
Bone: maximum moment	0.6	1.0	2.1	1.2	1.1	1.5	1.1	1.2	-1.0	1.1	0.8	-0.2	0.0
Mean time between licks in bursts	0.1	0.2	1.0	-0.2	-0.2	1.0	-0.4	0.1	0.5	0.2	0.4	-0.1	-0.2
Mean num. licks in bursts	0.1	0.2	0.7	-0.4	-0.3	-0.4	-0.4	-0.2	0.9	0.1	-0.1	0.3	0.3
Cd content in liver	0.8	0.8	1.7	0.3	0.3	-1.0	0.3	0.8	-1.0	-1.3	-1.3	1.2	0.9
Co content in liver	0.1	0.1	0.3	-0.4	-0.4	0.4	-0.4	0.2	0.2	-0.5	-0.2	0.5	-0.1
Cu content in liver	1.8	2.2	7.1	1.9	1.9	-0.8	1.7	2.7	-1.9	0.1	0.2	-0.4	-0.7
Fe content in liver	2.0	2.3	5.9	1.3	1.3	2.4	1.0	1.1	-0.8	2.0	2.0	-1.5	-1.0
K content in liver	1.2	1.2	1.9	-1.3	-1.3	-1.2	-1.4	-0.7	0.9	-1.0	-1.2	1.0	0.4
Mg content in liver	0.2	0.2	0.8	-0.2	-0.2	-0.8	-0.0	0.9	-0.2	0.0	-0.2	-0.0	-0.6
Mn content in liver	1.3	1.4	2.4	-1.3	-1.3	-1.1	-1.2	-0.6	1.0	-1.3	-1.3	1.6	1.0
Na content in liver	0.4	0.4	1.0	0.5	0.5	1.0	0.4	0.8	-0.0	0.7	0.9	-0.3	0.0
Rb content in liver	0.2	0.3	0.8	-0.9	-0.9	-0.4	-0.6	-0.1	0.1	-0.4	-0.7	0.3	0.1
Se content in liver	1.1	1.4	2.5	-1.0	-1.0	-1.6	-1.1	-0.3	1.0	-1.3	-1.5	1.4	1.0
Sr content in liver	0.1	0.1	0.1	-0.4	-0.4	-0.2	-0.3	0.1	0.2	0.1	0.1	0.2	-0.0
Zn content in liver	0.9	1.0	4.1	0.5	0.5	-1.6	0.8	2.0	-1.1	-0.1	0.1	-0.3	-1.0
Bone: minimum diameter	0.9	1.6	3.7	-1.0	-1.0	-0.0	-0.9	-1.2	0.7	-1.5	-1.4	1.8	1.9
Time in familiar zone, hab. session 1	2.2	2.1	3.5	1.8	1.8	0.8	1.8	1.9	-1.7	1.0	1.1	-1.1	-0.9
Time in novel zone, hab. session 1	0.1	0.1	0.2	-0.1	-0.1	-0.5	-0.1	-0.5	0.1	0.1	-0.3	-0.1	-0.2
Total zone transitions, hab. session 1	1.7	2.4	6.4	1.4	1.2	2.5	1.2	1.0	-0.5	2.2	1.9	-1.4	-1.0
Total locomotion distance, hab. session 1	0.9	1.3	6.6	0.9	0.7	2.6	0.7	0.2	-0.1	1.7	1.3	-0.7	-0.3
Locomotion velocity, hab. session 1	0.9	1.3	6.7	0.6	0.4	2.6	0.4	0.0	0.4	1.7	1.5	-0.7	-0.2
Time in familiar zone, hab. session 2	1.2	1.3	2.6	1.5	1.5	0.3	1.3	0.9	-1.6	0.8	0.8	-1.2	-0.6
Time in novel zone, hab. session 2	0.5	0.5	0.9	-1.0	-0.9	-0.8	-0.8	-0.6	1.0	-0.6	-0.6	0.6	0.2
Total zone transitions, hab. session 2	0.1	0.2	0.7	-0.3	-0.4	-0.2	-0.4	-0.5	0.8	0.6	0.2	-0.2	-0.4
Total locomotion distance, hab. session 2	0.1	0.1	0.6	0.2	0.1	0.4	-0.0	0.1	0.4	0.8	0.5	-0.3	-0.2
Locomotion velocity, hab. session 2	0.1	0.2	0.7	0.1	-0.0	0.6	-0.1	0.1	0.6	0.8	0.6	-0.3	-0.2
Novel to familiar place preference ratio	3.6	3.7	7.1	-2.0	-2.1	-1.2	-2.0	-2.7	1.2	-1.9	-2.2	1.8	1.6
Novelty place preference	3.5	3.5	6.7	-1.9	-2.0	-1.2	-1.9	-2.6	1.2	-1.9	-2.2	1.8	1.6
Time in novel zone, NPP test	2.5	2.6	5.5	-1.6	-1.7	-1.0	-1.6	-2.3	0.9	-1.6	-2.0	1.5	1.3
Total zone transitions, NPP test	3.3	4.8	7.6	1.9	1.9	2.6	1.9	2.0	-1.1	2.8	2.4	-2.3	-2.4
Total locomotion distance, NPP test	1.8	2.5	4.6	1.7	1.5	2.0	1.5	1.4	-0.9	2.2	1.7	-1.5	-1.1
Locomotion velocity, NPP test	0.9	1.3	3.0	1.2	1.1	1.7	1.0	1.0	-0.5	1.5	1.2	-0.9	-0.5
Intraocular pressure	1.6	2.3	3.7	-1.2	-1.2	-1.6	-1.6	-1.4	1.3	-1.7	-1.5	1.9	1.5
Delta distance traveled before/after self-admin	0.5	0.5	1.3	-0.7	-0.6	-0.9	-0.2	-0.6	0.2	-0.9	-1.1	0.5	1.1
Delta ambulatory time before/after self-admin	1.8	2.0	3.7	-1.5	-1.4	-1.4	-1.1	-1.2	0.9	-1.7	-1.9	1.4	1.3
Parametrial fat weight	0.1	0.1	0.4	-0.3	-0.3	0.2	-0.3	-0.3	0.3	-0.2	-0.2	0.0	0.6
Pavlov. Cond. lever latency	0.3	0.4	3.4	0.4	0.3	-1.8	0.3	-0.1	-0.3	-0.3	-0.6	-0.2	0.1
Pavlov. Cond. magazine entry latency	0.2	0.3	0.9	-0.6	-0.5	0.5	-0.6	-0.4	1.0	0.4	0.7	-0.0	0.5
Pavlov. Cond. change in total contacts	0.5	0.5	1.7	-0.7	-0.6	1.3	-0.7	-0.6	0.8	-0.1	0.1	0.5	0.9
Pavlov. Cond. index score	0.4	0.5	2.8	-0.3	-0.2	1.7	-0.3	-0.0	0.5	0.8	1.2	-0.3	-0.1
Pavlov. Cond. latency score	0.3	0.4	2.6	-0.5	-0.4	1.6	-0.4	-0.0	0.6	0.5	0.8	0.1	0.1
Pavlov. Cond. lever contacts	0.8	1.0	5.9	-0.3	-0.3	2.4	-0.3	0.1	0.8	1.0	1.2	-0.3	-0.5
Pavlov. Cond. magazine entry number	0.3	0.4	1.9	0.2	0.1	-1.4	0.2	0.2	-0.5	-0.6	-1.1	0.3	-0.7
Pavlov. Cond. intertrial magazine entries	1.9	2.2	5.0	1.4	1.5	1.0	1.5	0.7	-1.0	1.8	1.2	-2.0	-2.2
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.6	2.6	-0.4	-0.3	1.6	-0.4	-0.1	0.6	0.8	1.2	-0.3	-0.2
Pavlov. Cond. response bias	0.9	1.1	5.9	-0.1	-0.1	2.4	-0.1	-0.0	0.6	1.3	1.7	-0.7	-0.2
Pavlov. Cond. lever latency	1.6	2.1	2.7	-1.6	-1.6	-1.0	-1.6	-1.6	1.7	-1.5	-1.4	1.6	0.9
Pavlov. Cond. magazine entry latency	0.4	0.5	1.3	-0.9	-0.9	0.1	-0.9	-0.8	1.1	-0.0	-0.3	0.2	0.3
Pavlov. Cond. change in total contacts	0.2	0.3	1.4	-0.5	-0.5	0.0	-0.6	-0.2	0.0	-0.6	-0.6	0.6	1.2
Pavlov. Cond. index score	0.1	0.2	0.4	0.4	0.4	0.6	0.4	0.4	-0.5	0.4	0.2	-0.4	0.2
Pavlov. Cond. latency score	0.0	0.0	0.2	0.1	0.1	0.3	0.1	0.2	-0.3	0.1	-0.2	-0.1	0.5
Pavlov. Cond. lever contacts	1.0	1.4	1.7	1.2	1.2	1.2	1.2	1.3	-1.2	1.3	1.2	-1.3	-0.7
Pavlov. Cond. magazine entry number	0.1	0.1	0.6	0.2	0.1	-0.7	0.1	-0.1	-0.3	-0.3	-0.1	0.1	0.1
Pavlov. Cond. intertrial magazine entries	0.3	0.4	2.0	0.5	0.6	-1.4	0.6	0.5	-0.6	0.1	0.4	-0.6	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	0.2	0.2	0.5	0.2	0.3	-0.4	0.3	0.1	-0.2	0.3
Pavlov. Cond. response bias	0.4	0.6	1.8	0.6	0.6	1.4	0.5	0.7	-0.5	0.9	0.9	-0.8	-0.4
Time in closed arm before self-admin	3.2	3.6	5.5	1.5	1.8	0.7	2.1	2.1	-2.3	1.7	2.0	-2.3	-1.7
Time in closed arm after self-admin	0.7	0.7	1.4	-1.0	-1.0	0.4	-0.8	-1.2	0.5	-0.8	-0.7	0.8	1.0
Time in open arm before self-admin	2.6	2.8	4.9	-1.3	-1.4	-0.4	-1.5	-1.4	1.7	-2.0	-1.8	2.2	2.2
Time in open arm after self-admin	0.3	0.4	1.2	-0.7	-0.7	-1.1	-0.6	-0.2	0.7	0.0	-0.2	0.2	-0.7
Bone: periosteal estimation	0.3	0.7	1.8	-0.6	-0.6	1.1	-0.6	-0.6	0.5	-0.7	-0.6	1.2	1.3
Bone: periosteal perimeter	0.1	0.2	0.9	-0.2	-0.2	0.4	-0.2	0.1	0.1	-0.5	-0.6	1.0	0.8
Bone: post-yield work	1.1	1.5	2.7	-1.3	-1.4	-1.4	-1.5	-0.9	1.7	-0.7	-0.9	1.2	0.5
Progressive ratio test 1 active lever presses	0.9	0.9	2.1	-1.5	-1.4	0.1	-1.2	-1.3	1.3	-0.0	-0.2	0.2	-0.2
Progressive ratio test 1 breakpoint	0.5	0.6	1.4	-1.2	-1.1	0.1	-1.0	-1.1	0.9	-0.0	-0.2	0.1	-0.2
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.3	-0.6	-0.4	-0.2	-0.5	-0.4	0.4	-0.2	-0.1	0.2	-0.5
Progressive ratio test 2 active lever presses	0.5	0.6	1.4	-1.2	-1.1	-0.6	-0.9	-0.6	0.8	-0.5	-0.5	0.5	0.0
Progressive ratio test 2 breakpoint	0.7	0.8	1.9	-1.4	-1.3	-1.0	-1.1	-0.5	1.0	-0.6	-0.6	0.5	0.0
Progressive ratio test 2 inactive lever presses	0.2	0.2	1.0	-0.3	-0.1	-0.3	-0.1	1.0	-0.2	-0.3	-0.1	0.1	-0.8
Incentive Sensitization - Responses	0.3	0.3	0.8	-0.7	-0.8	-0.9	-0.6	0.4	0.5	-0.4	-0.4	0.3	-0.1
Incentive Sensitization - Breakpoint	0.3	0.3	0.9	-0.6	-0.8	-0.9	-0.6	0.5	0.4	-0.4	-0.4	0.2	-0.1
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.4	0.1	0.3	0.6	0.3	-0.5	0.3	0.4	0.5	-0.4	0.6
Progressive ratio	0.5	0.6	2.5	0.5	0.9	1.6	0.6	0.7	-0.9	-0.1	0.3	-0.0	0.8
Food seeking constrained by brief footshock	0.6	0.8	1.3	0.7	0.7	0.6	1.0	1.1	-1.1	0.8	0.8	-1.1	-0.7
Seeking ratio, punishment vs. effort	0.3	0.3	1.0	-0.2	-0.5	-1.0	-0.1	0.0	0.4	0.6	0.3	-0.6	-1.0
Retroperitoneal fat weight	0.7	2.3	4.4	-1.1	-1.1	-1.9	-1.2	-1.0	0.3	-2.1	-2.0	1.9	1.4
Reaction time number correct	0.6	0.9	2.1	-0.0	0.2	1.3	0.3	0.6	-0.2	1.4	1.1	-1.2	-1.4
Reaction time mean minus median	0.2	0.3	1.2	0.0	-0.2	-1.1	-0.4	-0.5	-0.0	-0.6	-0.7	0.5	0.6
Reaction time mean minus median AUC	0.6	0.8	2.2	0.1	-0.1	-0.9	-0.3	-0.3	-0.6	-1.4	-1.3	1.1	1.5
Reaction time num false alarms	0.8	1.1	2.9	-0.2	0.1	0.5	0.3	0.9	0.2	1.5	1.5	-1.4	-1.7
Reaction time num false alarms AUC	0.7	1.0	2.8	-0.3	-0.1	0.8	0.1	0.5	0.5	1.6	1.4	-1.3	-1.7
Reaction time trials correct on left	0.6	0.9	2.1	-0.0	0.2	1.3	0.3	0.6	-0.2	1.4	1.1	-1.2	-1.4
Reaction time trials on left	0.6	0.8	2.0	-0.1	0.2	1.2	0.2	0.5	-0.1	1.3	1.1	-1.2	-1.4
Reaction time mean	2.1	3.0	4.6	-1.5	-1.7	-2.1	-1.8	-1.5	1.3	-2.0	-2.0	1.8	1.3
Reaction time mean AUC	3.4	4.5	5.6	-2.1	-2.2	-2.3	-2.3	-2.0	1.8	-2.3	-2.4	2.2	1.6
Median of all reaction times	3.2	4.3	5.5	-2.2	-2.4	-2.2	-2.3	-2.0	2.0	-2.1	-2.2	2.1	1.3
Reaction time omissions	1.7	2.3	4.8	-1.6	-1.5	-2.2	-1.4	-1.5	1.8	-1.4	-1.4	1.3	0.8
Reaction time false alarm rate	0.1	0.2	0.6	-0.6	-0.5	-0.1	-0.4	-0.1	0.8	0.4	0.3	-0.2	-0.6
Reaction time premature initiation rate	1.6	2.2	4.1	1.3	1.5	0.6	1.6	1.3	-1.5	1.7	1.3	-2.0	-1.6
Reaction time premature initiations	2.5	3.6	6.6	1.4	1.7	1.3	1.8	1.6	-1.7	2.4	1.9	-2.6	-2.2
Std. dev. reaction times	0.3	0.4	1.3	-0.0	-0.3	-1.1	-0.4	-0.4	-0.1	-0.8	-0.8	0.6	0.5
Reaction time trials completed	0.6	0.8	2.0	-0.1	0.2	1.2	0.2	0.5	-0.1	1.3	1.1	-1.2	-1.4
Reaction time trials AUC	0.7	1.0	2.5	0.0	0.3	1.3	0.3	0.8	-0.2	1.4	1.3	-1.3	-1.6
Run reversals in cocaine runway, females	1.5	1.4	3.2	1.5	1.8	0.4	1.2	1.2	-1.6	1.0	0.7	-0.7	-1.1
Run reversals in cocaine runway, males	1.4	1.4	2.2	-1.4	-1.5	-0.1	-1.2	-1.2	1.0	-1.3	-1.1	1.0	1.2
Latency to leave start box in cocaine runway	0.6	0.7	4.3	-0.0	0.0	2.1	-0.1	0.1	0.9	0.8	0.9	-0.3	-0.1
Latency to leave start box in cocaine runway, F	0.4	0.4	2.2	-0.1	-0.0	1.5	0.0	-0.1	0.8	0.6	0.8	-0.3	0.3
Latency to leave start box in cocaine runway, M	1.1	1.1	3.8	0.5	0.5	2.0	0.1	0.5	0.3	1.2	1.2	-0.7	-1.6
Std. dev. time between licks in bursts	3.0	3.6	6.9	2.3	2.3	1.9	2.2	2.3	-2.6	1.1	1.2	-1.1	-0.7
Total sessions with >9 infusions	0.4	0.4	1.4	-0.9	-0.9	0.3	-0.8	-1.2	0.5	0.4	-0.1	-0.1	-0.3
Short access day 1 total inactive lever presses	0.4	0.4	2.1	-0.3	-0.3	0.5	-0.4	-0.1	0.3	0.8	0.6	-0.5	-1.5
Short access day 10 total inactive lever presses	0.1	0.1	0.3	0.1	0.1	-0.3	-0.0	0.6	-0.3	-0.4	-0.2	0.4	-0.5
Short access day 1 total infusions	1.3	1.4	3.0	-1.7	-1.7	0.4	-1.6	-1.2	1.5	-0.5	-0.8	0.9	0.1
Short access day 10 total infusions	2.6	2.8	6.0	-2.5	-2.4	-0.9	-2.3	-2.0	2.2	-0.6	-0.9	0.9	0.3
Short access total infusions	1.1	1.2	2.9	-1.7	-1.6	0.5	-1.5	-1.4	1.3	0.0	-0.1	0.2	-0.3
Short access day 1 locomotion	0.3	0.3	1.0	0.6	0.7	0.8	0.7	0.2	-1.0	0.3	0.2	-0.3	-0.2
Short access day 10 total locomotion	0.4	0.4	0.9	-0.8	-0.9	-0.6	-0.9	-0.5	0.7	-0.4	-0.6	0.3	0.1
Short access total locomotion	0.3	0.4	0.7	-0.8	-0.9	-0.4	-0.9	-0.8	0.5	-0.2	-0.4	0.2	-0.1
One hour access (0.3 mA shock)	0.7	0.8	2.2	-1.2	-1.0	-1.5	-1.0	-0.6	0.8	0.1	-0.0	-0.0	-0.9
Compulsive drug intake	0.1	0.1	0.7	-0.1	0.1	-0.0	0.2	-0.8	0.1	-0.1	0.1	0.3	0.5
One hour access (shock baseline)	0.4	0.5	1.0	-0.9	-0.9	-0.9	-0.9	-0.0	0.6	0.1	-0.0	-0.0	-1.0
Social response proportion	0.2	0.2	0.9	0.3	0.2	-0.6	0.3	-0.3	-0.2	-0.3	-0.6	0.4	0.9
Social responses	1.7	2.1	3.4	1.8	1.7	0.3	1.8	1.8	-1.7	1.4	1.1	-1.4	-0.8
Social time	0.8	1.1	3.1	-1.3	-1.3	-1.8	-1.2	-0.8	1.3	-0.3	-0.7	0.5	0.2
Soleus weight	0.2	0.5	2.4	-0.3	-0.4	1.5	-0.4	-0.2	0.6	0.9	1.0	-0.2	-0.4
Bone: stiffness	0.5	0.8	2.2	-0.6	-0.6	1.2	-0.7	0.1	1.1	-0.5	-0.5	1.5	1.1
Tibialis anterior weight	0.0	0.1	0.5	-0.1	0.0	0.5	-0.0	0.7	0.1	0.2	0.3	0.1	-0.5
Time to tail flick, vehicle, before self-admin	0.5	0.5	1.7	-0.9	-0.8	0.1	-1.0	-1.3	0.8	-0.4	-0.3	0.3	-0.2
Time to tail flick, vehicle, after self-admin	0.6	0.6	1.9	-0.6	-0.4	-0.3	-0.3	-1.3	0.2	-0.9	-0.8	0.7	1.4
Time to tail flick, test, before self-admin	2.2	2.2	4.5	1.2	1.2	1.4	1.3	1.1	-1.2	1.6	1.5	-1.7	-2.1
Time to tail flick, test, after self-admin	0.8	0.8	4.6	-0.5	-0.4	2.2	-0.4	-0.3	0.8	0.8	0.9	-0.4	-0.8
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	1.7	-0.1	-0.2	-0.3	-0.1	-0.2	0.3	-0.6	-0.7	0.7	1.3
Delta time to tail flick, test, before/after SA	1.5	1.4	2.9	-1.7	-1.5	0.1	-1.6	-0.7	1.7	-0.7	-0.5	1.3	0.7
Tibia length	0.3	0.9	4.4	-0.5	-0.5	0.8	-0.6	-0.7	0.7	-1.0	-0.5	1.2	2.1
Ambulatory time before self-admin	3.0	3.1	4.6	1.8	1.9	1.5	1.6	1.0	-1.5	2.1	2.1	-1.9	-1.7
Ambulatory time after self-admin	1.1	1.2	1.9	1.1	1.1	-0.3	1.2	0.6	-1.1	1.3	0.9	-1.4	-1.1
Bone: tissue strength	0.9	0.9	1.2	-1.0	-1.0	-0.8	-1.0	-0.8	0.9	-0.9	-1.1	1.1	0.7
Total heroin consumption	0.5	0.5	1.5	0.1	0.3	1.2	0.1	0.1	0.4	1.0	1.2	-1.0	-0.5
Bone: trabecular number	0.4	0.6	1.4	1.2	1.2	-0.1	1.1	1.0	-0.9	0.3	0.7	-0.4	0.0
Bone: trabecular spacing	0.4	0.5	1.1	-1.0	-1.0	-0.7	-0.9	-0.5	1.0	-0.3	-0.3	0.2	-0.4
Bone: trabecular thickness	1.3	1.5	2.5	1.6	1.5	1.5	1.4	1.5	-1.2	0.8	1.1	-0.7	-0.1
Bone: trabecular tissue density	0.4	0.6	1.5	0.7	0.6	0.7	0.6	1.0	-0.6	0.6	0.7	-0.8	-1.2
Water consumed over 24 hours	0.3	0.3	1.0	0.0	0.1	-0.1	0.1	0.1	0.5	0.8	1.0	-0.6	-1.0
Number of responses in last shaping day	1.4	1.4	2.3	-1.3	-1.4	-0.8	-1.5	-0.9	1.3	-1.1	-1.4	1.4	0.5