Hub : Genes

Sdhaf1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Sdhaf1 0.39 0.16 0.0e+00 0.31 0.31 0.31 0.31 4.9e-35 8.4e-35 9.5e-35 4.2e-35
2 PL gene expression Sdhaf1 0.1 0.06 4.1e-11 0.06 0.09 0.1 0.1 3.6e-07 1.9e-10 7.9e-11 5.0e-11
3 BLA gene expression Sdhaf1 0.05 0.04 3.7e-03 0.03 0.03 0.02 0.03 9.5e-03 1.3e-02 4.7e-02 7.5e-03
4 Liver gene expression Sdhaf1 0.03 0.02 1.5e-03 0.02 0.02 0.02 0.02 2.8e-03 4.6e-03 6.3e-03 4.9e-03
5 Brain gene expression Sdhaf1 0.04 0.03 9.5e-05 0.04 0.05 0.04 0.03 8.6e-05 2.9e-05 2.7e-04 7.5e-04
6 IC gene expression Sdhaf1 0.1 0.06 5.3e-05 0.1 0.05 0.04 0.02 7.7e-05 3.7e-03 6.3e-03 6.2e-02
7 OFC gene expression Sdhaf1 0.3 0.17 2.5e-04 0.07 0.03 0.1 0.05 8.2e-03 6.2e-02 2.8e-03 2.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.61.12.20.90.60.80.91.01.31.5
Area under the delay curve0.60.71.10.81.01.01.10.60.7-0.2
BMI with tail0.10.30.6-0.6-0.1-0.6-0.4-0.6-0.1-0.8
BMI without tail0.30.91.51.01.20.91.20.90.80.3
Body weight3.012.916.53.73.53.33.23.64.13.7
Weight adjusted by age0.10.10.20.00.2-0.5-0.50.00.40.5
Bone surface1.52.83.21.71.81.61.71.61.81.5
Bone volume1.52.73.61.61.61.51.61.61.91.8
Breakpoint value in progressive ratio session1.61.93.21.51.41.71.81.31.10.5
Number of licking bursts2.94.75.8-2.4-1.5-2.4-2.4-2.4-1.9-2.1
Context. condit. distance diff. score0.00.10.2-0.10.4-0.1-0.1-0.2-0.2-0.4
Locomotion velocity, session 10.40.51.0-0.7-1.0-0.6-0.7-0.7-0.60.0
Locomotion distance, session 10.50.61.00.81.00.80.90.60.80.6
Locomotion velocity, session 20.50.61.4-0.7-0.8-0.6-0.5-0.7-1.2-0.8
Locomotion distance, session 21.21.72.5-1.3-0.8-1.3-1.2-1.5-1.4-1.6
Locomotion velocity, session 30.30.30.5-0.6-0.4-0.6-0.7-0.6-0.6-0.4
Locomotion distance, session 32.93.26.42.02.51.91.81.71.40.6
Stereotopy head waving bouts, day 30.50.62.0-0.7-1.4-0.7-0.7-0.6-0.7-0.1
Stereotopy head waving duration, day 31.31.53.8-1.2-1.9-1.2-1.3-1.1-1.0-0.6
Locomotion velocity, session 70.30.41.00.61.00.50.60.50.50.2
Locomotion distance, session 70.20.20.50.40.60.40.40.40.30.7
Stereotopy head waving bouts, day 71.82.02.7-1.4-0.9-1.5-1.5-1.6-1.3-1.6
Stereotopy head waving duration, day 72.22.73.1-1.6-1.5-1.7-1.7-1.8-1.5-1.7
Locomotion velocity, session 83.84.55.2-2.2-1.6-2.1-2.1-2.3-2.2-2.2
Locomotion distance, session 80.81.12.0-1.0-0.1-1.0-1.0-1.2-1.1-1.4
Degree of sensitization distance0.60.61.3-0.9-1.2-0.8-0.7-0.6-0.50.2
Degree of sensitization stereotypy1.41.52.6-1.2-0.5-1.3-1.2-1.4-1.0-1.6
Conditioned locomotion0.40.51.3-0.6-0.5-0.5-0.5-0.8-0.8-1.1
Cocaine response after cond. corrected0.10.10.5-0.3-0.7-0.2-0.2-0.0-0.20.3
Cocaine response after cond. not corrected0.10.10.5-0.1-0.7-0.0-0.00.2-0.20.6
Cocaine response before conditioning1.31.61.81.31.11.31.21.31.31.3
Saline control response0.00.10.2-0.2-0.4-0.1-0.1-0.2-0.4-0.0
Bone: connectivity density0.20.40.50.70.50.60.60.70.70.6
Bone: cortical apparent density1.62.22.7-1.7-1.4-1.6-1.6-1.5-1.4-1.1
Bone: cortical area1.62.43.31.51.41.51.61.61.31.8
Bone: cortical porosity1.11.23.4-0.9-0.2-1.0-1.0-1.1-0.9-1.8
Bone: cortical porosity1.71.84.5-1.2-0.4-1.3-1.3-1.4-1.2-2.1
Bone: cortical thickness0.50.91.90.80.60.81.01.00.81.4
Bone: cortical thickness0.60.70.8-0.9-0.9-0.9-0.9-0.8-0.8-0.4
Bone: cortical tissue density1.82.53.0-1.7-1.5-1.7-1.7-1.7-1.5-1.3
Condit. Reinf. active minus inactive responses0.20.20.3-0.4-0.4-0.3-0.4-0.4-0.3-0.5
Condit. Reinf. active-inactive response ratio0.20.20.7-0.4-0.8-0.3-0.4-0.2-0.2-0.2
Condit. Reinf. active responses1.92.43.4-1.6-1.3-1.4-1.4-1.7-1.6-1.8
Condit. Reinf. inactive responses2.22.64.5-1.6-0.9-1.5-1.4-1.8-1.8-2.1
Incentive salience index mean0.20.20.6-0.4-0.3-0.3-0.3-0.4-0.4-0.8
Condit. Reinf. lever presses0.10.10.50.10.30.10.2-0.0-0.2-0.7
Condit. Reinf. active minus inactive responses1.31.72.61.51.11.51.61.50.80.9
Condit. Reinf. active-inactive response ratio0.10.10.3-0.3-0.4-0.3-0.2-0.2-0.5-0.1
Condit. Reinf. active responses3.44.86.12.42.22.42.52.31.81.5
Condit. Reinf. inactive responses4.35.67.72.72.82.62.52.42.11.2
Condit. Reinf. lever presses7.810.712.43.53.13.53.53.43.12.7
Condit. Reinf. lever reinforcers received3.75.16.52.52.42.52.52.41.91.5
Conditioned reinforcement - actives0.61.01.6-1.3-1.3-1.0-1.0-1.0-0.8-0.5
Conditioned reinforcement - inactives0.30.41.10.51.00.60.50.10.1-1.0
Conditioned locomotion2.22.93.2-1.7-1.7-1.7-1.5-1.8-1.8-1.7
Patch foraging indifference point 0 sec0.10.20.30.40.50.60.40.50.3-0.0
Patch foraging indifference point AUC0.60.91.2-0.9-0.9-0.8-1.0-1.0-1.1-0.9
Delay disc. indifference point, 0s delay0.50.51.10.41.01.10.90.10.6-0.4
Delay disc. indifference point, 16s delay1.21.32.41.11.41.51.61.00.7-0.3
Delay disc. indifference point, 2s delay1.01.22.01.21.41.11.10.91.10.5
Delay disc. indifference point, 24s delay2.02.23.31.61.81.51.61.51.30.6
Delay disc. indifference point, 4s delay0.10.10.5-0.10.40.30.2-0.1-0.0-0.7
Delay disc. indifference point, 8s delay0.10.20.30.30.50.40.40.40.40.1
Indifference point function ln k0.30.50.80.60.50.80.90.70.60.7
Indifference point function log k0.30.50.80.60.50.80.90.70.60.7
Patch foraging total patch changes 0 sec0.10.20.40.50.60.70.50.60.40.1
Patch foraging total patch changes 12 sec0.00.00.10.0-0.20.30.20.1-0.1-0.2
Patch foraging total patch changes 18 sec0.10.20.3-0.40.1-0.5-0.6-0.4-0.4-0.4
Patch foraging total patch changes 24 sec0.40.71.80.71.30.70.60.71.00.5
Patch foraging total patch changes 6 sec0.00.00.10.10.1-0.1-0.30.2-0.2-0.1
Patch foraging time to switch 0 sec0.40.71.3-1.0-1.2-0.7-0.4-0.7-1.0-0.7
Patch foraging water rate 0 sec0.40.91.6-0.7-0.6-1.0-1.3-0.9-1.1-1.0
Patch foraging water rate 12 sec0.30.71.60.91.10.40.10.61.20.7
Patch foraging water rate 18 sec0.10.20.4-0.1-0.4-0.6-0.6-0.3-0.1-0.3
Patch foraging water rate 24 sec0.20.30.90.10.7-0.4-0.3-0.30.1-0.9
Patch foraging water rate 6 sec0.81.12.81.21.70.70.50.91.30.5
Seeking ratio, delayed vs. immediate footshock1.11.43.10.91.81.11.21.01.40.4
Distance traveled before self-admin0.30.51.50.50.11.11.20.40.10.1
Distance traveled after self-admin2.32.93.51.91.51.81.81.81.41.5
Extensor digitorum longus weight0.20.71.5-0.9-1.2-1.0-1.0-0.7-0.50.3
Bone: elastic displacement0.00.00.20.0-0.3-0.00.00.10.10.4
Bone: elastic work1.92.43.01.51.31.51.61.61.71.6
Bone: endosteal estimation1.73.74.12.02.02.02.02.01.71.7
Bone: endosteal perimeter1.42.93.71.81.91.91.91.71.31.3
Epididymis fat weight0.00.10.2-0.20.0-0.4-0.2-0.10.50.4
Delta time in closed arm before/after self-admin1.11.01.41.11.10.90.71.01.21.1
Delta time in open arm before/after self-admin0.60.61.5-0.7-0.7-1.2-0.9-0.7-0.6-0.5
Diff in mean of infusions in LGA sessions0.40.52.0-0.4-0.4-0.10.1-0.6-1.0-1.4
Delay discount exponential model param0.70.71.2-0.9-1.1-1.0-1.0-0.8-0.80.0
Extinction: sum of active levers before priming4.34.76.12.11.52.22.52.22.12.5
Active lever presses in extinction session 62.42.44.21.50.31.81.81.61.02.1
Bone: final force1.72.83.11.61.61.61.81.81.71.6
Bone: final moment2.33.74.21.91.81.92.02.01.91.9
Food consumed during 24 hour testing period0.70.92.21.01.51.01.00.80.80.2
Glucose0.30.51.3-0.7-1.1-0.7-0.7-0.5-0.40.4
Heart weight0.10.10.30.50.40.10.10.20.2-0.3
Delay discount hyperbolic model param0.50.50.9-0.7-1.0-0.8-0.9-0.6-0.70.1
Intermittent access intake day 1-15 change1.12.24.11.51.50.90.91.42.01.7
Intermittent access intake escalation0.81.63.51.11.10.60.61.21.91.8
Intermittent access intake escalation 21.21.32.20.90.71.11.11.31.31.5
Intermitt. access day 1 inactive lever presses1.66.09.12.72.82.83.02.51.70.9
Intermitt. access day 15 inactive lever presses0.61.23.01.21.70.91.21.00.8-0.3
Intermitt. access escalation Index0.10.10.4-0.3-0.0-0.3-0.2-0.5-0.3-0.7
Intermittent access day 1 total infusions1.42.34.0-1.7-0.9-1.4-1.2-1.9-1.4-2.0
Intermittent access day 15 total infusions0.10.10.2-0.40.2-0.4-0.1-0.40.4-0.3
Intermittent access terminal intake (last 3 days)0.30.31.0-0.7-0.1-0.5-0.2-0.7-0.2-1.0
Intermittent access total infusions0.50.61.3-1.0-0.3-0.7-0.5-1.0-0.4-1.1
Intermittent access day 1 locomotion1.01.24.4-0.9-0.1-0.5-0.3-1.2-1.2-2.1
Intermittent access day 15 total locomotion0.10.10.50.10.50.0-0.0-0.2-0.0-0.7
Intermittent access total locomotion1.01.22.8-1.1-0.6-0.8-0.8-1.3-1.1-1.7
Intermittent access standard deviation2.24.65.52.12.42.22.32.12.31.5
Left kidney weight2.09.113.72.92.72.42.33.03.73.7
Right kidney weight2.612.017.63.42.83.13.03.54.04.2
Cocaine induced anxiety0.00.00.00.0-0.0-0.10.10.10.10.1
Post-drug Anxiety0.10.10.4-0.1-0.10.30.3-0.1-0.4-0.6
Baseline Anxiety0.10.10.50.20.50.40.20.0-0.2-0.7
Tail length4.919.221.44.64.24.44.34.54.34.3
Length with tail6.929.833.45.85.25.45.15.65.75.4
Length without tail3.09.612.63.32.92.72.53.23.53.4
Times rat made contact with spout0.80.91.4-1.2-1.2-1.1-1.1-0.9-0.30.4
Lifetime Intake0.70.91.4-1.2-0.6-1.0-0.8-1.2-0.6-1.0
Liver weight, left0.50.81.1-1.0-1.0-1.1-1.0-1.0-0.8-0.6
Liver weight, right0.30.51.1-0.6-1.0-0.8-0.6-0.6-0.9-0.3
Locomotor activity0.40.62.1-0.7-1.5-0.5-0.9-0.5-0.70.1
Locomotor testing distance0.61.02.1-1.1-1.5-0.9-1.1-0.9-0.8-0.2
Locomotor testing rearing1.83.65.3-2.1-1.9-2.3-2.2-1.9-1.6-1.0
Locomotion in novel chamber0.20.30.7-0.1-0.70.50.4-0.1-0.8-0.5
Locomotion in novel chamber post-restriction0.30.41.30.1-0.21.01.20.2-0.4-0.5
Fecal boli incidents, locomotor time 12.13.04.8-1.6-2.2-1.4-0.9-1.5-2.2-1.9
Change in fecal boli incidents, locomotor task0.10.10.40.1-0.40.1-0.10.2-0.10.6
Time >=10cm from walls, locomotor time 10.10.10.2-0.4-0.3-0.2-0.1-0.1-0.4-0.2
Bouts of movement, locomotor time 10.80.92.00.91.41.21.10.70.70.0
Total resting periods, locomotor time 10.80.91.70.81.21.31.20.70.6-0.1
Rest time, locomotor task time 11.11.42.8-1.0-1.4-0.5-0.5-1.2-1.5-1.7
Distance moved, locomotor task time 10.10.10.2-0.10.4-0.3-0.4-0.10.20.5
Vertical activity count, locomotor time 10.81.93.61.51.91.00.91.41.41.3
Time >=10cm from walls, locomotor time 21.11.63.1-1.2-1.2-0.8-0.9-1.2-1.7-1.5
Bouts of movement, locomotor time 20.00.00.0-0.1-0.00.00.2-0.00.00.1
Total resting periods, locomotor time 20.00.00.1-0.2-0.2-0.20.0-0.2-0.2-0.1
Rest time, locomotor task time 20.30.40.8-0.4-0.7-0.4-0.3-0.5-0.7-0.9
Distance moved, locomotor task time 20.20.20.7-0.40.2-0.5-0.9-0.50.1-0.0
Vertical activity count, locomotor time 20.60.91.91.01.41.00.60.81.00.7
Light reinforcement 10.10.30.6-0.5-0.1-0.6-0.8-0.5-0.3-0.5
Light reinforcement 22.23.33.9-1.8-1.9-2.0-1.8-1.8-1.8-1.7
Bone: marrow area1.73.84.32.01.92.12.12.01.71.8
Bone: maximum diameter1.42.52.81.61.61.61.71.71.41.6
Bone: maximum force2.85.05.62.22.22.22.32.32.42.1
Bone: maximum moment3.46.06.42.42.42.42.52.52.52.4
Mean time between licks in bursts0.00.10.30.20.50.10.10.1-0.1-0.6
Mean num. licks in bursts1.32.04.11.30.61.31.51.51.42.0
Cd content in liver0.20.20.5-0.4-0.4-0.6-0.7-0.4-0.1-0.1
Co content in liver0.40.50.7-0.6-0.8-0.8-0.7-0.6-0.8-0.5
Cu content in liver1.11.31.61.21.21.11.01.11.31.0
Fe content in liver0.30.30.5-0.5-0.7-0.5-0.4-0.5-0.6-0.7
K content in liver0.10.10.10.30.20.30.20.3-0.0-0.1
Mg content in liver0.40.40.9-0.5-1.0-0.5-0.6-0.4-0.9-0.5
Mn content in liver0.50.61.7-0.6-1.3-0.6-0.6-0.5-1.0-0.3
Na content in liver0.70.70.90.91.00.90.90.90.80.8
Rb content in liver0.10.10.7-0.2-0.1-0.1-0.2-0.4-0.3-0.8
Se content in liver5.56.59.1-2.6-3.0-2.5-2.5-2.4-2.8-1.9
Sr content in liver0.20.20.3-0.3-0.5-0.4-0.5-0.3-0.5-0.2
Zn content in liver2.32.53.4-1.5-1.6-1.8-1.8-1.5-1.5-1.3
Bone: minimum diameter3.46.18.62.62.92.72.82.52.01.6
Time in familiar zone, hab. session 10.50.52.00.50.10.50.40.70.51.4
Time in novel zone, hab. session 11.51.53.9-1.1-0.6-1.2-1.1-1.2-1.0-2.0
Total zone transitions, hab. session 10.00.00.1-0.10.40.00.1-0.2-0.1-0.3
Total locomotion distance, hab. session 11.21.82.71.41.31.61.61.31.10.6
Locomotion velocity, hab. session 10.81.21.91.10.91.31.41.10.90.6
Time in familiar zone, hab. session 22.12.23.01.70.91.71.61.71.11.3
Time in novel zone, hab. session 21.31.31.9-1.4-0.9-1.4-1.3-1.3-0.8-0.9
Total zone transitions, hab. session 22.93.84.5-2.0-1.5-1.9-1.8-2.1-2.0-2.1
Total locomotion distance, hab. session 20.20.21.1-0.20.1-0.1-0.2-0.4-0.2-1.0
Locomotion velocity, hab. session 20.20.21.0-0.3-0.1-0.2-0.3-0.5-0.4-1.0
Novel to familiar place preference ratio0.10.10.30.30.50.10.20.30.40.1
Novelty place preference0.10.10.20.20.5-0.00.00.20.30.1
Time in novel zone, NPP test0.00.00.1-0.00.3-0.2-0.2-0.10.1-0.1
Total zone transitions, NPP test0.00.00.1-0.2-0.2-0.1-0.1-0.3-0.20.0
Total locomotion distance, NPP test2.73.74.52.01.62.12.11.91.91.8
Locomotion velocity, NPP test2.94.05.12.11.62.32.22.02.01.8
Intraocular pressure0.10.10.3-0.10.00.00.3-0.2-0.5-0.5
Delta distance traveled before/after self-admin1.81.92.61.61.60.90.81.51.61.6
Delta ambulatory time before/after self-admin1.62.02.91.61.70.80.71.51.71.5
Parametrial fat weight0.30.61.6-0.4-1.3-0.9-0.9-0.2-0.60.7
Pavlov. Cond. lever latency0.10.10.50.20.10.10.10.30.50.7
Pavlov. Cond. magazine entry latency0.70.91.2-1.0-1.1-1.0-0.9-0.9-0.8-0.8
Pavlov. Cond. change in total contacts0.50.51.6-0.5-0.1-0.5-0.5-0.7-0.8-1.2
Pavlov. Cond. index score0.50.60.8-0.8-0.7-0.8-0.6-0.8-0.8-0.9
Pavlov. Cond. latency score0.20.30.7-0.5-0.4-0.5-0.3-0.5-0.7-0.9
Pavlov. Cond. lever contacts0.10.10.20.20.20.20.40.1-0.3-0.4
Pavlov. Cond. magazine entry number0.50.60.80.90.80.90.80.90.70.8
Pavlov. Cond. intertrial magazine entries0.70.91.7-0.9-1.0-0.7-0.9-1.0-1.3-0.7
Pavlov. Cond. lever-magazine prob. diff.0.81.01.2-1.0-0.9-1.0-0.9-1.0-1.0-1.1
Pavlov. Cond. response bias0.30.40.7-0.6-0.8-0.6-0.5-0.5-0.6-0.4
Pavlov. Cond. lever latency5.16.97.7-2.7-2.7-2.6-2.6-2.7-2.8-2.1
Pavlov. Cond. magazine entry latency3.64.45.12.22.02.32.22.22.11.5
Pavlov. Cond. change in total contacts7.011.313.23.43.63.33.43.43.62.6
Pavlov. Cond. index score5.97.99.02.92.82.82.92.93.02.3
Pavlov. Cond. latency score5.26.97.62.72.72.72.72.72.82.0
Pavlov. Cond. lever contacts5.47.48.42.82.92.72.72.82.92.2
Pavlov. Cond. magazine entry number4.35.27.0-2.3-2.2-2.2-2.2-2.3-2.7-2.1
Pavlov. Cond. intertrial magazine entries1.01.52.1-1.2-0.9-1.3-1.3-1.3-1.5-1.1
Pavlov. Cond. lever-magazine prob. diff.5.57.48.72.82.72.72.82.83.02.3
Pavlov. Cond. response bias6.48.610.13.03.12.92.93.03.22.4
Time in closed arm before self-admin1.62.03.3-1.8-1.0-1.4-1.2-1.6-1.3-1.6
Time in closed arm after self-admin0.40.41.00.20.61.01.00.20.1-0.6
Time in open arm before self-admin4.65.06.12.41.72.42.12.51.92.4
Time in open arm after self-admin0.80.82.11.10.60.30.31.01.01.4
Bone: periosteal estimation2.34.95.52.22.22.32.32.32.02.3
Bone: periosteal perimeter1.52.63.61.61.41.81.91.71.11.5
Bone: post-yield work2.23.25.11.82.31.91.91.71.71.0
Progressive ratio test 1 active lever presses0.10.10.2-0.10.40.10.4-0.20.2-0.4
Progressive ratio test 1 breakpoint0.10.10.30.00.50.30.5-0.10.3-0.4
Progressive ratio test 1 inactive lever presses0.40.61.50.41.20.60.80.10.1-1.1
Progressive ratio test 2 active lever presses0.20.30.8-0.9-0.6-0.2-0.2-0.7-0.2-0.3
Progressive ratio test 2 breakpoint0.30.41.1-1.0-0.7-0.3-0.3-0.8-0.3-0.4
Progressive ratio test 2 inactive lever presses0.60.92.10.51.11.41.40.40.2-0.8
Incentive Sensitization - Responses0.50.71.5-1.2-0.9-0.7-0.6-0.9-0.7-0.5
Incentive Sensitization - Breakpoint0.50.61.4-1.2-0.9-0.7-0.6-0.9-0.6-0.5
Sum of active levers in priming session hrs 5-60.00.00.1-0.1-0.20.10.1-0.2-0.4-0.0
Progressive ratio0.10.10.3-0.0-0.10.20.50.0-0.3-0.5
Food seeking constrained by brief footshock2.93.55.12.11.72.22.32.01.51.3
Seeking ratio, punishment vs. effort0.40.61.10.91.00.80.60.70.70.5
Retroperitoneal fat weight0.72.87.3-1.4-2.7-1.8-1.8-1.0-1.30.6
Reaction time number correct0.10.10.30.0-0.2-0.6-0.6-0.10.00.2
Reaction time mean minus median0.20.50.70.80.80.50.30.70.70.8
Reaction time mean minus median AUC0.41.01.81.11.10.60.31.01.21.3
Reaction time num false alarms1.11.52.5-1.4-1.0-1.6-1.4-1.2-0.8-1.0
Reaction time num false alarms AUC1.11.82.7-1.4-1.2-1.6-1.5-1.3-1.0-1.1
Reaction time trials correct on left0.10.10.30.0-0.2-0.6-0.6-0.10.00.2
Reaction time trials on left0.10.10.40.0-0.2-0.6-0.6-0.10.00.3
Reaction time mean0.10.20.40.30.5-0.0-0.10.30.60.7
Reaction time mean AUC0.10.10.30.20.4-0.1-0.10.20.50.5
Median of all reaction times0.00.10.1-0.10.1-0.4-0.4-0.10.20.2
Reaction time omissions0.10.20.4-0.2-0.3-0.6-0.6-0.10.10.5
Reaction time false alarm rate0.60.91.3-1.1-0.8-1.0-0.8-1.0-0.7-1.0
Reaction time premature initiation rate0.10.20.50.30.60.30.20.10.3-0.7
Reaction time premature initiations0.10.10.40.30.5-0.1-0.2-0.00.2-0.6
Std. dev. reaction times0.40.81.40.91.20.40.30.71.21.0
Reaction time trials completed0.10.10.40.0-0.2-0.6-0.6-0.10.00.3
Reaction time trials AUC0.10.20.5-0.1-0.5-0.7-0.7-0.2-0.10.3
Run reversals in cocaine runway, females0.60.61.40.91.20.20.20.61.10.7
Run reversals in cocaine runway, males0.40.41.3-0.3-1.1-0.6-0.50.1-0.10.8
Latency to leave start box in cocaine runway0.20.30.90.60.90.2-0.00.10.80.2
Latency to leave start box in cocaine runway, F0.10.20.30.20.6-0.4-0.6-0.20.3-0.2
Latency to leave start box in cocaine runway, M0.10.10.30.10.40.30.20.00.50.2
Std. dev. time between licks in bursts0.50.61.30.81.10.80.70.5-0.2-1.1
Total sessions with >9 infusions1.21.52.2-1.5-1.3-1.3-1.3-1.3-1.0-0.6
Short access day 1 total inactive lever presses0.60.82.50.81.60.80.90.40.6-0.7
Short access day 10 total inactive lever presses1.74.17.02.02.52.62.51.81.30.3
Short access day 1 total infusions0.10.10.2-0.30.1-0.2-0.1-0.2-0.4-0.3
Short access day 10 total infusions0.30.40.8-0.9-0.7-0.6-0.4-0.8-0.4-0.4
Short access total infusions0.81.01.7-1.3-1.0-1.0-0.9-1.1-0.9-0.6
Short access day 1 locomotion1.21.52.2-1.4-1.0-1.4-1.5-1.2-1.0-0.9
Short access day 10 total locomotion0.40.82.00.71.11.21.40.70.3-0.4
Short access total locomotion1.11.32.1-1.3-0.9-0.9-0.8-1.2-1.3-1.5
One hour access (0.3 mA shock)0.60.71.50.71.20.90.90.50.9-0.1
Compulsive drug intake0.10.10.40.30.6-0.0-0.1-0.0-0.1-0.7
One hour access (shock baseline)0.00.10.2-0.20.10.30.4-0.10.4-0.2
Social response proportion2.52.84.71.91.52.22.21.71.20.8
Social responses0.91.22.31.51.01.41.31.10.30.0
Social time2.73.75.02.12.22.02.21.81.81.2
Soleus weight0.00.10.2-0.3-0.3-0.4-0.3-0.3-0.30.0
Bone: stiffness1.52.42.81.51.51.61.71.51.61.3
Tibialis anterior weight0.10.40.8-0.6-0.9-0.7-0.6-0.3-0.20.9
Time to tail flick, vehicle, before self-admin0.30.30.8-0.5-0.3-0.9-0.7-0.6-0.4-0.5
Time to tail flick, vehicle, after self-admin0.70.92.51.00.41.61.50.80.20.1
Time to tail flick, test, before self-admin0.30.30.5-0.40.5-0.6-0.7-0.60.6-0.4
Time to tail flick, test, after self-admin0.10.10.2-0.3-0.4-0.1-0.2-0.2-0.4-0.3
Delta time to tail flick, vehicle, before/after SA0.90.91.71.10.71.31.01.00.70.5
Delta time to tail flick, test, before/after SA0.50.51.7-0.4-1.2-0.1-0.1-0.1-1.3-0.2
Tibia length2.67.110.12.52.52.52.52.63.22.8
Ambulatory time before self-admin0.40.61.70.60.31.21.30.5-0.0-0.1
Ambulatory time after self-admin4.45.26.72.62.32.42.42.32.11.8
Bone: tissue strength2.92.94.61.72.11.71.81.71.81.0
Total heroin consumption0.50.61.00.71.00.91.00.50.80.0
Bone: trabecular number1.32.13.11.41.41.31.41.41.81.4
Bone: trabecular spacing0.30.30.60.70.20.70.60.80.50.6
Bone: trabecular thickness0.10.20.5-0.5-0.2-0.7-0.5-0.40.10.2
Bone: trabecular tissue density1.82.75.9-1.8-2.4-1.6-1.7-1.5-1.4-0.0
Water consumed over 24 hours0.40.61.00.60.60.70.70.80.91.0
Number of responses in last shaping day0.10.20.50.10.40.70.50.20.40.2