Hub : Genes

Scp2d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Scp2d1 0.11 0.05 3.2e-05 0.07 0.11 0.09 0.09 5.6e-04 1.8e-05 1.0e-04 1.5e-04
2 NAcc gene expression Scp2d1 0.15 0.05 0.0e+00 0.2 0.12 0.2 0.2 4.1e-30 2.4e-18 1.9e-29 1.1e-29
3 IL gene expression Scp2d1 0.27 0.13 8.3e-04 0.13 0.06 0.08 0.07 4.7e-04 1.4e-02 5.2e-03 8.0e-03
4 BLA gene expression Scp2d1 0.27 0.11 4.4e-09 0.17 0.16 0.17 0.17 2.7e-09 4.7e-09 3.3e-09 3.5e-09
5 Brain gene expression Scp2d1 0.2 0.07 0.0e+00 0.27 0.24 0.25 0.26 1.4e-25 7.7e-22 3.6e-23 1.9e-24
6 PL gene expression Scp2d1 0.22 0.07 0.0e+00 0.21 0.21 0.21 0.21 1.1e-22 9.8e-23 3.1e-22 9.6e-23
7 RMTg gene expression Scp2d1 0.17 0.08 3.7e-04 0.12 0.03 0.05 0.08 3.7e-04 7.3e-02 1.7e-02 4.3e-03
8 pVTA gene expression Scp2d1 0.09 0.04 1.2e-06 0.09 0.08 0.09 0.09 5.3e-08 4.1e-07 1.2e-07 1.4e-07
9 LHb gene expression Scp2d1 0.35 0.13 3.6e-06 0.18 0.11 0.14 0.04 4.5e-05 1.6e-03 4.1e-04 3.7e-02
10 OFC gene expression Scp2d1 0.4 0.15 2.3e-05 0.16 0.13 0.14 0.1 1.5e-04 5.4e-04 3.8e-04 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.30.50.7-0.7-0.3-0.6-0.60.6-0.5-0.5-0.6-0.5
Area under the delay curve0.81.22.70.8-1.6-0.9-1.1-1.11.0-1.3-1.3-0.8-0.6
BMI with tail6.623.030.0-5.55.15.34.74.7-4.83.93.94.94.9
BMI without tail3.317.422.3-4.74.64.34.34.3-4.33.53.54.04.0
Body weight5.825.534.2-5.85.55.55.25.3-5.14.34.34.74.7
Weight adjusted by age0.51.62.71.3-0.7-1.1-1.2-0.81.1-1.7-1.7-1.4-1.2
Bone surface0.51.01.5-0.70.90.81.11.0-1.01.21.21.01.1
Bone volume0.00.00.10.20.0-0.00.20.20.00.30.3-0.10.0
Breakpoint value in progressive ratio session1.12.03.1-1.31.30.71.81.8-1.71.51.51.11.2
Number of licking bursts0.10.30.70.0-0.5-0.2-0.5-0.40.4-0.9-0.9-0.5-0.5
Context. condit. distance diff. score0.00.00.10.20.3-0.00.20.20.10.10.1-0.2-0.1
Locomotion velocity, session 10.20.30.70.50.3-0.90.50.4-0.30.70.70.20.2
Locomotion distance, session 12.63.45.32.0-2.0-2.3-1.9-2.01.9-1.4-1.4-1.6-1.5
Locomotion velocity, session 20.50.61.81.0-1.3-1.0-0.9-0.90.7-0.2-0.2-0.4-0.3
Locomotion distance, session 23.04.28.62.4-2.0-2.9-1.7-1.82.0-1.2-1.2-2.3-2.3
Locomotion velocity, session 32.12.43.31.8-1.6-1.7-1.5-1.61.6-1.5-1.5-1.4-1.4
Locomotion distance, session 30.91.01.31.1-1.1-1.0-1.0-1.01.1-0.9-0.9-0.9-0.9
Stereotopy head waving bouts, day 30.10.10.1-0.30.40.00.30.3-0.40.30.30.30.2
Stereotopy head waving duration, day 30.30.30.5-0.50.70.30.70.7-0.70.50.50.50.5
Locomotion velocity, session 72.12.32.61.6-1.5-1.5-1.5-1.41.5-1.5-1.5-1.6-1.6
Locomotion distance, session 70.91.11.60.9-0.9-1.2-0.9-0.91.1-1.0-1.0-1.3-1.3
Stereotopy head waving bouts, day 70.00.00.1-0.30.10.20.10.1-0.20.10.10.20.1
Stereotopy head waving duration, day 70.00.00.00.20.0-0.10.0-0.1-0.00.10.10.0-0.1
Locomotion velocity, session 80.20.21.00.7-0.1-1.00.00.10.10.50.5-0.3-0.3
Locomotion distance, session 81.92.84.82.0-1.5-2.2-1.4-1.41.7-1.2-1.2-1.8-1.7
Degree of sensitization distance0.00.00.1-0.30.2-0.10.10.20.00.10.1-0.2-0.3
Degree of sensitization stereotypy0.20.30.4-0.50.50.40.60.6-0.50.50.50.40.4
Conditioned locomotion0.10.10.40.40.3-0.50.60.5-0.20.00.0-0.3-0.3
Cocaine response after cond. corrected2.53.74.41.7-1.8-2.0-2.0-1.92.0-1.8-1.8-2.1-2.1
Cocaine response after cond. not corrected4.46.47.62.4-2.4-2.6-2.5-2.52.7-2.3-2.3-2.7-2.8
Cocaine response before conditioning0.30.30.70.8-0.6-0.4-0.4-0.60.7-0.2-0.2-0.6-0.6
Saline control response0.50.71.7-0.21.1-0.41.00.9-0.51.31.3-0.1-0.2
Bone: connectivity density0.00.00.10.4-0.40.1-0.2-0.30.10.00.00.00.1
Bone: cortical apparent density0.10.20.50.3-0.30.7-0.3-0.10.0-0.6-0.60.50.5
Bone: cortical area0.20.30.9-0.10.30.90.10.1-0.3-0.0-0.00.90.9
Bone: cortical porosity0.91.01.4-0.90.90.80.90.8-1.11.01.01.21.2
Bone: cortical porosity1.11.21.7-1.01.10.91.11.0-1.21.11.11.31.3
Bone: cortical thickness0.61.02.9-0.30.51.70.50.5-0.80.10.11.71.6
Bone: cortical thickness1.11.32.71.1-1.3-0.4-1.2-1.31.1-1.6-1.6-0.4-0.4
Bone: cortical tissue density0.10.20.40.3-0.30.6-0.3-0.10.0-0.6-0.60.50.4
Condit. Reinf. active minus inactive responses0.30.30.90.3-0.5-0.5-0.5-0.40.5-0.1-0.1-0.9-1.0
Condit. Reinf. active-inactive response ratio0.50.51.20.4-0.6-0.7-0.6-0.50.7-0.7-0.7-1.0-1.1
Condit. Reinf. active responses0.30.30.80.4-0.6-0.6-0.5-0.50.6-0.1-0.1-0.9-0.9
Condit. Reinf. inactive responses0.10.10.3-0.00.10.10.20.2-0.20.60.60.20.2
Incentive salience index mean0.60.71.30.6-1.1-0.6-1.1-1.11.0-0.6-0.6-0.8-0.8
Condit. Reinf. lever presses0.50.81.90.4-1.3-0.2-1.4-1.41.0-0.7-0.7-0.3-0.2
Condit. Reinf. active minus inactive responses1.32.03.2-1.11.81.11.71.6-1.51.51.51.21.2
Condit. Reinf. active-inactive response ratio0.81.31.9-1.21.20.81.41.3-1.21.31.30.80.8
Condit. Reinf. active responses1.42.02.8-1.01.71.51.41.3-1.41.11.11.71.6
Condit. Reinf. inactive responses0.50.72.2-0.30.81.30.40.4-0.70.20.21.51.3
Condit. Reinf. lever presses3.55.16.7-2.02.61.92.52.4-2.32.62.61.81.7
Condit. Reinf. lever reinforcers received2.12.94.0-1.32.01.71.81.7-1.81.61.61.91.8
Conditioned reinforcement - actives0.31.02.91.0-0.6-1.70.2-0.60.80.30.3-1.6-1.5
Conditioned reinforcement - inactives0.61.53.51.3-0.6-1.7-0.6-0.71.2-0.8-0.8-1.9-1.8
Conditioned locomotion0.00.10.10.3-0.2-0.20.1-0.20.10.30.3-0.30.0
Patch foraging indifference point 0 sec0.51.42.21.2-0.3-1.2-1.1-0.91.2-1.4-1.4-1.3-1.5
Patch foraging indifference point AUC0.10.10.50.5-0.7-0.3-0.3-0.30.2-0.4-0.4-0.0-0.1
Delay disc. indifference point, 0s delay0.30.40.6-0.8-0.10.40.60.5-0.60.60.60.60.8
Delay disc. indifference point, 16s delay1.21.72.61.1-1.6-1.2-1.3-1.51.2-1.3-1.3-1.1-1.1
Delay disc. indifference point, 2s delay0.10.10.5-0.7-0.40.3-0.3-0.0-0.20.20.20.30.3
Delay disc. indifference point, 24s delay3.96.38.52.4-2.9-2.5-2.3-2.62.7-2.6-2.6-2.3-2.1
Delay disc. indifference point, 4s delay0.20.20.8-0.1-0.90.0-0.5-0.50.4-0.7-0.7-0.2-0.0
Delay disc. indifference point, 8s delay0.30.51.20.9-1.1-0.8-0.5-0.40.6-0.8-0.8-0.6-0.3
Indifference point function ln k0.10.20.40.60.0-0.4-0.4-0.50.6-0.3-0.3-0.5-0.6
Indifference point function log k0.10.20.40.60.0-0.4-0.4-0.50.6-0.3-0.3-0.5-0.6
Patch foraging total patch changes 0 sec0.51.52.21.3-0.4-1.4-1.1-0.91.2-1.4-1.4-1.3-1.5
Patch foraging total patch changes 12 sec0.10.10.30.10.1-0.0-0.30.10.0-0.6-0.60.30.1
Patch foraging total patch changes 18 sec0.71.72.41.5-1.0-1.4-1.1-0.91.1-1.5-1.5-1.3-1.4
Patch foraging total patch changes 24 sec0.10.30.60.4-0.3-0.8-0.7-0.50.5-0.7-0.7-0.5-0.4
Patch foraging total patch changes 6 sec1.01.72.51.1-0.8-1.1-1.4-1.21.4-1.6-1.6-1.2-1.3
Patch foraging time to switch 0 sec0.41.52.6-1.61.01.61.01.1-1.21.11.11.21.2
Patch foraging water rate 0 sec0.82.84.11.9-1.5-1.6-1.7-1.61.5-2.0-2.0-1.4-1.4
Patch foraging water rate 12 sec1.35.37.12.5-2.7-2.1-2.3-2.52.4-2.4-2.4-1.9-1.9
Patch foraging water rate 18 sec7.316.218.74.1-4.1-4.3-4.0-4.14.2-3.8-3.8-4.0-3.8
Patch foraging water rate 24 sec4.86.89.42.5-2.5-3.1-2.2-2.22.5-2.6-2.6-2.9-2.8
Patch foraging water rate 6 sec4.16.08.32.9-2.3-2.6-2.2-2.32.5-2.6-2.6-2.1-2.2
Seeking ratio, delayed vs. immediate footshock0.50.71.2-1.01.10.60.70.6-0.70.90.90.90.6
Distance traveled before self-admin0.10.10.4-0.6-0.10.70.20.0-0.3-0.0-0.00.40.6
Distance traveled after self-admin0.10.20.70.10.10.8-0.00.2-0.3-0.5-0.50.60.8
Extensor digitorum longus weight0.00.20.4-0.10.5-0.00.50.6-0.30.60.60.00.1
Bone: elastic displacement1.31.72.4-1.21.01.11.41.3-1.31.21.21.51.6
Bone: elastic work2.83.75.1-2.11.82.01.81.8-1.91.61.62.32.3
Bone: endosteal estimation0.30.81.7-1.21.2-0.10.90.9-0.61.31.3-0.1-0.0
Bone: endosteal perimeter0.10.20.5-0.10.4-0.70.30.20.00.60.6-0.5-0.5
Epididymis fat weight4.422.426.2-5.15.14.74.85.0-4.74.74.74.24.0
Delta time in closed arm before/after self-admin0.30.30.50.5-0.6-0.2-0.7-0.40.5-0.5-0.5-0.7-0.7
Delta time in open arm before/after self-admin1.82.22.7-1.61.51.51.61.5-1.51.51.51.21.3
Diff in mean of infusions in LGA sessions0.10.10.4-0.5-0.40.60.1-0.2-0.20.20.20.50.5
Delay discount exponential model param1.11.63.3-1.01.81.01.31.3-1.21.41.41.00.8
Extinction: sum of active levers before priming0.10.10.30.2-0.3-0.40.30.10.00.20.2-0.6-0.4
Active lever presses in extinction session 63.63.64.4-1.62.11.62.11.9-2.01.91.91.91.8
Bone: final force0.00.10.2-0.20.30.4-0.1-0.00.0-0.2-0.20.40.4
Bone: final moment0.00.10.2-0.10.30.3-0.1-0.10.1-0.2-0.20.40.4
Food consumed during 24 hour testing period0.20.30.80.1-0.7-0.3-0.7-0.90.8-0.4-0.4-0.6-0.6
Glucose1.01.62.7-1.11.40.81.41.5-1.31.61.60.80.8
Heart weight1.22.03.1-1.31.81.21.31.4-1.51.31.31.41.3
Delay discount hyperbolic model param0.71.02.3-0.61.50.71.11.0-0.91.11.10.80.5
Intermittent access intake day 1-15 change0.10.71.2-1.01.10.70.70.8-0.81.01.00.60.5
Intermittent access intake escalation0.10.40.7-0.80.90.50.40.5-0.60.80.80.50.4
Intermittent access intake escalation 20.20.31.0-1.00.80.70.40.3-0.40.60.60.30.2
Intermitt. access day 1 inactive lever presses0.11.01.61.2-0.8-1.2-1.0-0.81.1-0.8-0.8-1.1-1.3
Intermitt. access day 15 inactive lever presses0.00.10.50.00.70.00.10.3-0.0-0.1-0.1-0.5-0.6
Intermitt. access escalation Index0.92.74.0-0.81.51.12.01.9-1.72.02.01.41.3
Intermittent access day 1 total infusions0.10.30.7-0.10.30.30.80.6-0.40.50.50.60.8
Intermittent access day 15 total infusions0.40.91.2-0.81.10.91.00.9-0.90.90.90.91.0
Intermittent access terminal intake (last 3 days)0.81.31.8-1.11.21.11.21.1-1.21.11.11.31.3
Intermittent access total infusions1.11.41.7-1.01.31.01.31.2-1.21.21.21.11.2
Intermittent access day 1 locomotion0.10.10.40.2-0.40.10.3-0.1-0.10.30.30.40.7
Intermittent access day 15 total locomotion0.31.22.0-0.90.90.81.11.2-1.11.41.40.70.9
Intermittent access total locomotion0.20.30.6-0.30.20.30.50.5-0.50.70.70.50.7
Intermittent access standard deviation0.00.00.2-0.20.20.1-0.4-0.40.1-0.1-0.1-0.00.2
Left kidney weight0.76.07.0-2.42.62.22.62.6-2.52.62.62.22.1
Right kidney weight0.32.12.7-1.51.51.11.41.6-1.61.61.61.21.1
Cocaine induced anxiety0.10.20.50.40.5-0.10.20.7-0.60.30.30.30.3
Post-drug Anxiety0.20.30.5-0.40.60.60.50.6-0.70.30.30.50.6
Baseline Anxiety0.40.72.4-1.50.71.30.80.5-0.50.40.40.80.7
Tail length0.10.51.0-0.81.00.60.71.0-0.80.40.40.40.5
Length with tail0.83.45.3-2.02.11.72.02.3-1.91.81.81.21.2
Length without tail0.52.43.2-1.71.81.81.41.7-1.51.51.51.31.2
Times rat made contact with spout3.64.25.8-2.31.91.82.12.1-2.12.42.41.51.6
Lifetime Intake0.81.01.3-0.91.10.71.21.0-1.01.01.00.81.0
Liver weight, left0.40.71.4-0.91.20.61.01.1-0.90.60.60.40.4
Liver weight, right0.61.01.6-1.21.30.91.21.1-0.91.01.00.70.7
Locomotor activity0.20.30.6-0.80.60.40.50.6-0.60.50.50.50.5
Locomotor testing distance0.00.00.1-0.30.10.1-0.20.1-0.30.10.10.20.2
Locomotor testing rearing0.20.61.1-1.00.80.50.40.8-1.00.80.80.50.6
Locomotion in novel chamber0.60.82.21.5-0.4-1.1-0.5-0.20.7-0.7-0.7-1.0-1.1
Locomotion in novel chamber post-restriction0.72.23.21.8-1.0-1.8-1.4-1.41.5-1.5-1.5-1.3-1.4
Fecal boli incidents, locomotor time 10.92.33.91.6-1.3-2.0-1.5-1.01.3-1.3-1.3-1.8-1.8
Change in fecal boli incidents, locomotor task0.40.40.7-0.30.70.60.90.4-0.60.80.80.70.8
Time >=10cm from walls, locomotor time 10.20.30.50.6-0.5-0.5-0.3-0.70.6-0.2-0.2-0.6-0.7
Bouts of movement, locomotor time 13.14.05.51.6-2.2-2.3-1.6-1.91.9-1.8-1.8-2.3-2.3
Total resting periods, locomotor time 14.35.07.01.9-2.4-2.6-1.8-2.12.2-1.9-1.9-2.6-2.6
Rest time, locomotor task time 11.42.34.81.1-1.7-2.1-0.6-1.31.5-0.7-0.7-2.2-2.1
Distance moved, locomotor task time 10.10.40.90.2-0.20.8-0.9-0.4-0.1-0.4-0.40.90.8
Vertical activity count, locomotor time 10.10.61.1-0.70.61.10.30.4-0.80.70.70.90.9
Time >=10cm from walls, locomotor time 20.51.32.2-1.21.10.71.31.1-1.01.51.50.90.8
Bouts of movement, locomotor time 20.20.81.1-0.90.60.71.10.8-1.00.90.90.90.9
Total resting periods, locomotor time 20.20.81.3-0.90.70.81.11.0-1.00.90.90.90.9
Rest time, locomotor task time 20.20.30.50.4-0.7-0.6-0.3-0.30.4-0.6-0.6-0.7-0.7
Distance moved, locomotor task time 20.20.30.90.4-0.7-0.3-0.9-0.90.6-0.3-0.3-0.2-0.3
Vertical activity count, locomotor time 20.10.20.5-0.30.10.20.30.0-0.20.70.70.40.3
Light reinforcement 10.20.82.00.7-0.5-1.4-0.6-0.40.8-0.6-0.6-1.4-1.4
Light reinforcement 20.30.71.70.20.8-0.71.31.3-0.80.90.9-0.3-0.2
Bone: marrow area0.40.91.8-1.21.2-0.10.90.9-0.71.41.4-0.00.0
Bone: maximum diameter0.00.10.2-0.40.40.20.30.1-0.00.40.4-0.0-0.1
Bone: maximum force0.00.10.20.00.10.3-0.4-0.30.2-0.4-0.40.10.2
Bone: maximum moment0.00.10.20.10.10.2-0.4-0.40.3-0.3-0.30.10.2
Mean time between licks in bursts0.00.20.60.8-0.2-0.5-0.4-0.40.5-0.6-0.6-0.2-0.3
Mean num. licks in bursts0.82.03.9-1.21.31.01.41.3-1.32.02.01.21.2
Cd content in liver1.61.82.80.7-1.6-1.1-1.2-1.31.5-1.2-1.2-1.7-1.6
Co content in liver0.40.40.80.8-0.6-0.9-0.4-0.40.6-0.7-0.7-0.7-0.7
Cu content in liver1.11.32.11.0-1.2-0.9-1.1-1.21.1-1.5-1.5-0.9-0.9
Fe content in liver1.21.42.2-1.51.11.50.90.9-1.21.21.21.31.2
K content in liver0.60.61.00.9-0.7-0.2-0.8-1.00.7-1.0-1.00.50.4
Mg content in liver0.20.20.7-0.10.50.40.30.3-0.3-0.1-0.10.80.7
Mn content in liver0.20.31.11.10.5-0.80.50.6-0.2-0.0-0.0-0.0-0.0
Na content in liver2.02.34.4-1.01.31.81.11.1-1.51.31.32.12.0
Rb content in liver0.30.41.0-0.1-0.5-0.1-0.8-0.70.6-1.0-1.0-0.3-0.3
Se content in liver0.10.20.5-0.4-0.00.5-0.1-0.2-0.0-0.2-0.20.70.7
Sr content in liver0.60.51.11.0-0.5-0.9-0.5-0.50.7-0.6-0.6-0.9-0.9
Zn content in liver0.30.30.70.4-0.7-0.4-0.7-0.80.6-0.6-0.6-0.1-0.2
Bone: minimum diameter0.40.71.0-0.61.00.90.80.7-0.80.80.80.90.9
Time in familiar zone, hab. session 10.10.10.3-0.5-0.40.4-0.1-0.2-0.10.10.10.30.2
Time in novel zone, hab. session 10.20.30.8-0.30.9-0.00.60.7-0.50.60.60.00.1
Total zone transitions, hab. session 10.50.61.40.7-1.2-1.0-0.8-0.90.7-0.4-0.4-0.8-0.8
Total locomotion distance, hab. session 10.81.22.21.1-1.5-1.2-1.2-1.31.0-0.8-0.8-1.0-1.0
Locomotion velocity, hab. session 11.21.72.71.4-1.6-1.4-1.4-1.51.3-1.1-1.1-1.1-1.0
Time in familiar zone, hab. session 20.20.20.6-0.20.3-0.20.40.4-0.40.80.8-0.0-0.0
Time in novel zone, hab. session 20.10.10.2-0.50.40.40.40.4-0.20.20.20.30.3
Total zone transitions, hab. session 20.10.20.50.20.1-0.70.10.00.10.60.6-0.4-0.4
Total locomotion distance, hab. session 20.30.41.40.70.0-1.20.1-0.00.20.70.7-0.8-0.7
Locomotion velocity, hab. session 20.40.51.91.1-0.3-1.4-0.2-0.40.50.30.3-0.9-0.8
Novel to familiar place preference ratio0.20.20.40.1-0.4-0.2-0.5-0.50.5-0.6-0.6-0.5-0.6
Novelty place preference0.20.20.50.1-0.4-0.2-0.5-0.50.5-0.7-0.7-0.5-0.5
Time in novel zone, NPP test0.10.10.1-0.3-0.10.0-0.2-0.20.2-0.3-0.3-0.3-0.4
Total zone transitions, NPP test0.40.71.31.0-1.0-1.2-0.6-0.70.8-0.2-0.2-1.0-0.9
Total locomotion distance, NPP test0.91.33.01.4-1.0-1.7-0.8-0.91.1-0.1-0.1-1.6-1.5
Locomotion velocity, NPP test1.31.83.61.7-1.3-1.9-1.1-1.21.3-0.5-0.5-1.7-1.6
Intraocular pressure2.54.17.01.9-1.9-2.7-1.6-1.52.1-1.6-1.6-2.5-2.4
Delta distance traveled before/after self-admin0.10.10.30.60.30.2-0.10.2-0.1-0.4-0.40.50.5
Delta ambulatory time before/after self-admin0.10.10.30.50.30.1-0.00.2-0.0-0.6-0.60.30.2
Parametrial fat weight16.338.547.4-6.96.45.76.86.6-6.46.36.35.25.2
Pavlov. Cond. lever latency2.32.95.1-1.42.10.92.22.3-1.91.91.90.80.8
Pavlov. Cond. magazine entry latency0.30.31.3-0.50.21.10.0-0.0-0.40.20.20.90.8
Pavlov. Cond. change in total contacts3.03.35.41.5-2.0-0.6-2.3-2.31.9-2.3-2.3-0.8-0.8
Pavlov. Cond. index score0.70.91.90.6-1.20.3-1.3-1.40.9-1.1-1.10.10.0
Pavlov. Cond. latency score1.21.53.01.0-1.6-0.2-1.7-1.71.2-1.5-1.5-0.3-0.4
Pavlov. Cond. lever contacts1.21.53.20.8-1.6-0.4-1.7-1.81.4-1.3-1.3-0.3-0.4
Pavlov. Cond. magazine entry number0.20.20.70.20.3-0.80.40.5-0.10.40.4-0.5-0.4
Pavlov. Cond. intertrial magazine entries0.60.72.41.20.1-1.50.0-0.00.5-0.1-0.1-1.3-1.3
Pavlov. Cond. lever-magazine prob. diff.0.70.92.00.4-1.20.6-1.4-1.40.8-1.1-1.10.30.2
Pavlov. Cond. response bias0.40.61.20.2-0.90.5-1.1-1.10.7-0.9-0.90.20.1
Pavlov. Cond. lever latency2.53.54.82.2-1.9-2.0-1.9-1.81.8-2.0-2.0-1.6-1.4
Pavlov. Cond. magazine entry latency1.31.82.9-1.31.60.81.61.6-1.31.71.70.50.5
Pavlov. Cond. change in total contacts2.97.28.4-2.82.82.62.72.5-2.62.92.92.52.3
Pavlov. Cond. index score3.14.86.0-2.42.42.02.42.3-2.22.52.51.61.4
Pavlov. Cond. latency score2.33.74.9-2.22.11.82.12.0-1.92.12.11.51.3
Pavlov. Cond. lever contacts2.74.05.3-2.32.12.02.11.9-1.92.22.21.61.4
Pavlov. Cond. magazine entry number2.33.04.11.8-2.0-1.5-1.9-1.91.8-2.0-2.0-1.1-1.0
Pavlov. Cond. intertrial magazine entries0.71.52.21.3-1.3-0.9-1.4-1.41.3-1.5-1.5-0.8-0.7
Pavlov. Cond. lever-magazine prob. diff.3.85.86.9-2.62.52.32.62.5-2.42.62.61.91.8
Pavlov. Cond. response bias3.04.15.6-2.22.41.92.32.1-2.02.32.31.51.3
Time in closed arm before self-admin0.00.00.20.4-0.10.1-0.1-0.30.2-0.2-0.2-0.2-0.2
Time in closed arm after self-admin0.60.71.21.1-0.8-0.3-0.8-0.80.9-0.7-0.7-1.0-1.1
Time in open arm before self-admin0.50.60.9-0.80.70.20.70.8-0.70.90.90.91.0
Time in open arm after self-admin4.04.45.4-2.01.91.82.22.2-2.12.02.02.22.3
Bone: periosteal estimation0.30.61.1-0.91.00.40.80.7-0.70.90.90.50.5
Bone: periosteal perimeter0.10.20.5-0.30.60.20.50.5-0.40.70.70.30.4
Bone: post-yield work0.20.30.70.2-0.3-0.5-0.7-0.60.5-0.2-0.2-0.8-0.8
Progressive ratio test 1 active lever presses0.61.01.3-1.00.80.71.11.0-1.01.11.10.91.1
Progressive ratio test 1 breakpoint0.50.91.1-1.00.70.61.10.9-0.91.11.10.91.0
Progressive ratio test 1 inactive lever presses0.10.31.00.2-0.1-1.0-0.10.00.5-0.3-0.3-0.9-1.0
Progressive ratio test 2 active lever presses0.20.30.5-0.50.50.20.70.7-0.50.70.70.40.5
Progressive ratio test 2 breakpoint0.30.40.6-0.60.70.20.70.8-0.60.80.80.50.6
Progressive ratio test 2 inactive lever presses0.31.02.1-0.71.40.11.41.4-0.81.21.20.00.3
Incentive Sensitization - Responses0.10.30.6-0.00.7-0.30.70.8-0.30.70.7-0.00.1
Incentive Sensitization - Breakpoint0.20.51.1-0.20.9-0.00.91.1-0.61.01.00.20.3
Sum of active levers in priming session hrs 5-60.30.21.10.4-0.5-1.10.1-0.10.1-0.0-0.0-0.7-0.6
Progressive ratio0.41.13.51.0-0.7-1.9-0.7-0.40.6-0.6-0.6-1.4-1.4
Food seeking constrained by brief footshock0.10.10.20.3-0.4-0.4-0.5-0.30.0-0.0-0.00.50.2
Seeking ratio, punishment vs. effort0.92.14.1-1.41.02.01.10.8-1.11.31.32.01.8
Retroperitoneal fat weight12.957.777.8-8.87.78.07.87.7-7.67.27.26.96.8
Reaction time number correct0.72.44.01.5-1.1-1.9-1.1-1.21.3-1.5-1.5-2.0-2.0
Reaction time mean minus median0.52.93.8-2.01.91.51.71.7-1.71.81.81.61.5
Reaction time mean minus median AUC0.42.43.1-1.71.81.21.71.7-1.61.71.71.31.2
Reaction time num false alarms1.52.64.02.0-1.6-1.4-1.6-1.61.6-1.7-1.7-1.4-1.3
Reaction time num false alarms AUC1.12.43.31.8-1.6-1.3-1.6-1.61.5-1.7-1.7-1.3-1.3
Reaction time trials correct on left0.72.44.01.5-1.1-1.9-1.1-1.21.3-1.5-1.5-2.0-2.0
Reaction time trials on left0.62.23.91.5-1.0-1.9-1.0-1.11.3-1.4-1.4-2.0-1.9
Reaction time mean2.14.67.1-2.52.01.72.42.0-2.02.72.71.61.6
Reaction time mean AUC1.84.36.5-2.32.01.72.32.0-1.92.62.61.71.7
Median of all reaction times2.43.76.3-2.21.71.52.21.8-1.82.52.51.31.3
Reaction time omissions0.60.91.9-0.81.20.51.41.2-1.01.01.00.40.6
Reaction time false alarm rate0.40.51.01.0-0.9-0.4-0.8-0.90.8-0.7-0.7-0.4-0.3
Reaction time premature initiation rate0.20.40.60.5-0.5-0.6-0.8-0.70.8-0.5-0.5-0.5-0.6
Reaction time premature initiations0.61.82.51.3-1.0-1.5-1.3-1.21.4-1.2-1.2-1.5-1.6
Std. dev. reaction times0.93.14.2-2.11.71.51.91.7-1.72.02.01.51.4
Reaction time trials completed0.62.23.91.5-1.0-1.9-1.0-1.11.3-1.4-1.4-2.0-1.9
Reaction time trials AUC0.82.74.81.6-1.1-2.1-1.1-1.21.4-1.4-1.4-2.2-2.2
Run reversals in cocaine runway, females2.93.33.7-1.81.91.61.81.7-1.81.81.81.81.8
Run reversals in cocaine runway, males1.11.23.1-1.31.01.80.40.3-0.80.20.21.71.7
Latency to leave start box in cocaine runway0.10.20.50.40.7-0.00.40.7-0.40.40.40.10.2
Latency to leave start box in cocaine runway, F0.10.10.20.10.4-0.10.30.2-0.00.40.4-0.2-0.1
Latency to leave start box in cocaine runway, M0.40.41.30.70.90.10.31.1-0.80.30.30.50.5
Std. dev. time between licks in bursts0.61.11.51.2-1.0-1.1-0.9-0.91.1-1.2-1.2-0.9-0.9
Total sessions with >9 infusions1.11.41.9-1.31.10.81.10.9-1.11.41.41.01.4
Short access day 1 total inactive lever presses0.40.71.90.8-0.3-1.4-0.4-0.30.6-0.6-0.6-1.3-1.2
Short access day 10 total inactive lever presses0.10.72.80.50.1-1.1-0.10.10.50.10.1-1.4-1.7
Short access day 1 total infusions0.30.51.30.5-0.6-1.2-0.6-0.80.8-0.3-0.3-0.9-0.8
Short access day 10 total infusions0.20.30.6-0.60.60.40.60.7-0.60.60.60.30.5
Short access total infusions0.50.81.0-1.00.90.51.00.8-0.81.01.00.60.9
Short access day 1 locomotion0.50.91.6-0.81.00.70.80.6-0.91.11.11.11.3
Short access day 10 total locomotion0.31.01.80.9-1.2-1.0-1.1-1.01.0-0.6-0.6-1.3-1.1
Short access total locomotion0.10.10.6-0.1-0.00.10.2-0.1-0.20.40.40.30.8
One hour access (0.3 mA shock)0.50.61.7-0.30.5-0.01.30.7-0.71.31.30.20.2
Compulsive drug intake0.81.23.41.3-1.9-1.3-0.2-0.60.6-0.1-0.1-1.3-1.5
One hour access (shock baseline)0.40.91.6-1.11.31.20.80.6-0.80.70.71.11.2
Social response proportion5.67.18.2-2.72.72.52.82.9-2.82.62.62.52.6
Social responses0.10.10.2-0.50.20.3-0.10.2-0.3-0.2-0.20.10.3
Social time1.11.72.3-1.31.51.51.11.4-1.41.01.01.51.4
Soleus weight0.10.20.60.4-0.3-0.50.1-0.00.30.10.1-0.8-0.7
Bone: stiffness0.10.20.50.4-0.0-0.2-0.6-0.50.4-0.7-0.7-0.2-0.2
Tibialis anterior weight0.31.01.4-1.10.90.81.01.1-1.01.21.20.60.6
Time to tail flick, vehicle, before self-admin1.51.83.1-1.11.71.01.81.3-1.21.51.50.91.0
Time to tail flick, vehicle, after self-admin0.40.92.30.8-1.5-0.4-0.8-0.91.0-0.9-0.9-1.0-1.0
Time to tail flick, test, before self-admin0.10.10.40.1-0.6-0.6-0.1-0.50.40.10.1-0.3-0.2
Time to tail flick, test, after self-admin1.92.05.01.2-1.2-1.0-0.7-1.21.6-0.9-0.9-2.2-2.2
Delta time to tail flick, vehicle, before/after SA3.63.95.31.8-2.3-1.6-2.0-1.92.0-2.1-2.1-1.9-2.0
Delta time to tail flick, test, before/after SA0.50.61.70.7-0.4-0.3-0.4-0.50.8-0.6-0.6-1.3-1.3
Tibia length1.64.35.6-2.32.22.02.02.2-2.21.51.52.32.4
Ambulatory time before self-admin0.10.30.8-0.90.20.80.30.3-0.60.20.20.60.8
Ambulatory time after self-admin0.20.30.60.10.00.7-0.20.0-0.2-0.8-0.80.40.7
Bone: tissue strength0.60.71.2-0.90.70.70.80.8-0.71.11.10.60.6
Total heroin consumption0.70.81.6-0.40.8-0.31.31.2-1.01.21.2-0.10.2
Bone: trabecular number0.10.20.40.6-0.6-0.1-0.4-0.50.4-0.4-0.4-0.2-0.1
Bone: trabecular spacing0.60.91.9-1.40.91.40.70.7-0.90.30.31.11.1
Bone: trabecular thickness0.10.10.30.5-0.5-0.3-0.2-0.20.30.00.0-0.3-0.2
Bone: trabecular tissue density0.30.51.1-0.70.41.00.30.4-0.60.70.71.11.0
Water consumed over 24 hours0.10.20.7-0.1-0.2-0.70.0-0.00.10.40.4-0.8-0.7
Number of responses in last shaping day1.31.72.60.9-1.2-1.4-1.4-1.51.4-0.9-0.9-1.6-1.6