Hub : Genes

Scp2d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Scp2d1 0.06 0.04 9.0e-03 0.03 0.03 0.02 0.03 1.9e-02 1.9e-02 5.7e-02 2.6e-02
2 IL gene expression Scp2d1 0.44 0.18 1.2e-04 0.12 0.06 0.13 0.05 6.7e-04 1.3e-02 4.8e-04 2.6e-02
3 NAcc gene expression Scp2d1 0.18 0.07 0.0e+00 0.22 0.18 0.21 0.22 1.1e-25 5.6e-21 7.9e-24 7.5e-25
4 Brain gene expression Scp2d1 0.2 0.06 0.0e+00 0.28 0.26 0.27 0.27 7.1e-26 7.3e-24 4.4e-25 7.5e-25
5 BLA gene expression Scp2d1 0.26 0.1 1.0e-08 0.13 0.09 0.09 0.12 2.1e-07 1.3e-05 1.1e-05 4.6e-07
6 PL gene expression Scp2d1 0.23 0.08 0.0e+00 0.24 0.23 0.23 0.23 1.8e-26 1.5e-24 1.8e-25 2.2e-25
7 OFC gene expression Scp2d1 0.5 0.17 3.9e-06 0.2 0.2 0.15 0.17 2.2e-05 2.1e-05 1.8e-04 8.3e-05
8 RMTg gene expression Scp2d1 0.16 0.08 5.8e-04 0.12 0.05 0.1 0.13 3.7e-04 1.8e-02 1.1e-03 2.8e-04
9 LHb gene expression Scp2d1 0.42 0.14 1.8e-06 0.19 0.13 0.21 0.07 3.1e-05 5.5e-04 1.1e-05 8.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.30.41.20.6-0.5-0.5-0.6-0.3-0.41.10.8-0.7
Area under the delay curve1.11.22.01.4-0.8-1.4-1.3-1.4-1.00.50.9-0.8
BMI with tail4.915.920.2-3.94.54.34.04.03.8-4.1-3.33.9
BMI without tail5.210.814.5-3.73.23.33.53.83.5-2.4-3.02.9
Body weight4.318.022.6-4.84.64.74.64.34.3-3.6-3.33.7
Weight adjusted by age0.60.71.50.6-0.9-0.1-0.6-0.7-0.51.01.2-1.2
Bone surface0.51.01.9-0.90.90.91.01.41.20.0-0.90.9
Bone volume0.10.10.6-0.2-0.10.20.20.50.40.80.1-0.2
Breakpoint value in progressive ratio session1.51.62.4-1.21.00.91.31.51.5-1.3-1.31.3
Number of licking bursts0.30.40.60.5-0.5-0.6-0.7-0.8-0.80.10.8-0.6
Context. condit. distance diff. score0.00.10.2-0.1-0.00.20.20.30.30.40.2-0.2
Locomotion velocity, session 10.20.20.6-0.1-0.1-0.00.60.40.30.8-0.60.3
Locomotion distance, session 12.93.85.21.9-2.0-2.3-1.9-2.0-2.02.01.6-1.7
Locomotion velocity, session 21.01.12.21.2-0.9-1.5-1.1-1.0-1.01.30.3-0.6
Locomotion distance, session 23.44.810.11.4-2.6-2.2-1.9-1.9-1.93.21.9-2.2
Locomotion velocity, session 32.22.63.51.9-1.7-1.7-1.4-1.7-1.61.61.5-1.4
Locomotion distance, session 31.21.42.11.4-1.1-1.3-1.2-1.2-1.11.01.0-1.1
Stereotopy head waving bouts, day 30.20.30.9-0.40.40.60.50.30.3-0.9-0.50.5
Stereotopy head waving duration, day 30.40.50.7-0.50.60.80.80.70.6-0.8-0.70.7
Locomotion velocity, session 71.82.02.51.3-1.5-1.6-1.4-1.3-1.31.41.4-1.6
Locomotion distance, session 70.81.11.70.9-1.1-1.1-1.0-1.0-1.00.51.2-1.3
Stereotopy head waving bouts, day 70.10.10.2-0.40.30.30.40.40.4-0.1-0.30.1
Stereotopy head waving duration, day 70.00.00.10.0-0.0-0.10.00.00.00.4-0.10.0
Locomotion velocity, session 80.20.21.00.1-0.6-0.40.00.10.01.00.1-0.3
Locomotion distance, session 82.33.36.71.4-2.1-1.8-1.5-1.5-1.52.61.8-1.9
Degree of sensitization distance0.10.10.4-0.5-0.00.10.20.20.2-0.60.1-0.1
Degree of sensitization stereotypy0.20.30.4-0.60.50.50.60.60.6-0.3-0.40.4
Conditioned locomotion0.10.10.30.3-0.5-0.0-0.10.30.30.40.4-0.4
Cocaine response after cond. corrected2.73.03.91.2-1.9-1.9-1.8-1.8-1.81.51.7-2.0
Cocaine response after cond. not corrected5.35.87.41.9-2.6-2.5-2.3-2.4-2.42.42.5-2.7
Cocaine response before conditioning0.50.61.40.7-0.6-0.5-0.5-0.7-0.71.20.9-0.8
Saline control response1.01.43.9-2.00.51.31.31.41.4-0.1-0.80.5
Bone: connectivity density0.10.10.40.4-0.1-0.2-0.3-0.0-0.10.60.2-0.2
Bone: cortical apparent density0.10.20.80.90.1-0.2-0.5-0.4-0.4-0.10.20.2
Bone: cortical area0.10.20.50.00.70.40.20.50.40.4-0.40.5
Bone: cortical porosity1.51.62.4-1.21.31.31.21.31.2-1.1-1.51.4
Bone: cortical porosity1.61.72.2-1.11.31.51.21.41.3-1.1-1.41.4
Bone: cortical thickness0.40.71.60.21.30.70.60.80.60.0-0.91.2
Bone: cortical thickness1.41.64.32.1-0.9-1.3-1.4-1.2-1.30.51.3-0.9
Bone: cortical tissue density0.10.10.60.80.1-0.1-0.4-0.3-0.3-0.20.20.2
Condit. Reinf. active minus inactive responses0.40.40.80.1-0.6-0.5-0.6-0.6-0.60.70.7-0.9
Condit. Reinf. active-inactive response ratio0.50.50.90.3-0.7-0.7-0.8-0.7-0.70.40.9-0.9
Condit. Reinf. active responses0.40.51.00.3-0.7-0.6-0.7-0.7-0.71.00.7-0.9
Condit. Reinf. inactive responses0.00.00.0-0.10.10.10.20.10.10.2-0.20.2
Incentive salience index mean1.11.32.10.8-0.8-1.2-1.2-1.2-1.31.40.9-1.1
Condit. Reinf. lever presses0.81.01.81.0-0.3-1.3-1.2-1.2-1.31.10.5-0.6
Condit. Reinf. active minus inactive responses1.62.02.9-1.71.21.51.71.61.7-0.2-1.31.1
Condit. Reinf. active-inactive response ratio1.51.63.2-1.81.11.21.31.31.4-0.4-1.31.0
Condit. Reinf. active responses1.11.52.0-0.91.41.31.41.21.3-0.6-1.21.3
Condit. Reinf. inactive responses0.30.30.60.70.80.50.50.20.3-0.7-0.40.8
Condit. Reinf. lever presses3.95.37.1-2.72.22.52.62.52.5-1.4-2.22.0
Condit. Reinf. lever reinforcers received1.72.43.3-1.41.71.71.81.61.7-0.8-1.61.6
Conditioned reinforcement - actives0.90.92.7-0.1-1.2-1.0-0.7-0.3-0.71.60.8-1.1
Conditioned reinforcement - inactives2.02.33.50.8-1.7-1.4-1.2-1.2-1.61.91.7-1.8
Conditioned locomotion0.10.10.5-0.1-0.1-0.30.0-0.1-0.20.7-0.00.2
Patch foraging indifference point 0 sec0.40.71.70.4-1.2-0.2-0.3-0.9-0.50.81.3-1.2
Patch foraging indifference point AUC0.10.10.50.6-0.3-0.7-0.5-0.3-0.20.20.0-0.1
Delay disc. indifference point, 0s delay0.30.30.7-0.30.80.0-0.00.60.6-0.4-0.90.5
Delay disc. indifference point, 16s delay2.22.23.01.7-1.5-1.7-1.6-1.7-1.50.91.4-1.2
Delay disc. indifference point, 2s delay0.10.10.3-0.20.4-0.3-0.3-0.4-0.0-0.6-0.30.2
Delay disc. indifference point, 24s delay7.06.89.53.1-2.4-3.0-2.8-2.8-2.71.62.4-2.3
Delay disc. indifference point, 4s delay0.20.20.40.6-0.2-0.6-0.6-0.5-0.4-0.20.4-0.4
Delay disc. indifference point, 8s delay0.70.81.51.2-0.9-1.2-1.0-0.8-0.60.70.7-0.6
Indifference point function ln k0.20.30.70.3-0.7-0.1-0.4-0.5-0.50.70.8-0.8
Indifference point function log k0.20.30.70.3-0.7-0.1-0.4-0.5-0.50.70.8-0.8
Patch foraging total patch changes 0 sec0.50.81.70.5-1.2-0.3-0.3-0.9-0.51.01.3-1.2
Patch foraging total patch changes 12 sec0.00.00.10.10.30.00.2-0.10.2-0.40.00.1
Patch foraging total patch changes 18 sec0.91.11.91.1-1.4-0.8-0.9-1.0-0.81.01.4-1.2
Patch foraging total patch changes 24 sec0.20.20.40.2-0.4-0.3-0.3-0.6-0.40.70.4-0.4
Patch foraging total patch changes 6 sec0.60.91.80.6-1.0-0.7-0.7-1.2-0.90.71.3-1.1
Patch foraging time to switch 0 sec0.91.42.1-1.21.41.21.01.21.1-1.1-1.21.1
Patch foraging water rate 0 sec1.62.63.21.8-1.8-1.5-1.4-1.8-1.71.51.8-1.3
Patch foraging water rate 12 sec3.96.08.22.9-2.4-2.6-2.4-2.7-2.52.02.5-2.0
Patch foraging water rate 18 sec11.815.918.33.8-4.3-4.2-3.8-4.1-4.03.64.1-3.8
Patch foraging water rate 24 sec3.85.37.72.2-2.8-2.4-2.2-2.1-2.11.62.6-2.3
Patch foraging water rate 6 sec4.36.38.12.8-2.8-2.5-2.3-2.4-2.52.32.6-2.3
Seeking ratio, delayed vs. immediate footshock0.60.71.2-1.10.80.60.70.70.5-1.0-1.10.8
Distance traveled before self-admin0.10.10.3-0.10.30.1-0.2-0.1-0.0-0.6-0.40.2
Distance traveled after self-admin0.40.50.90.20.80.60.50.60.6-0.8-0.81.0
Extensor digitorum longus weight0.10.30.7-0.80.30.50.60.60.70.5-0.40.2
Bone: elastic displacement1.11.21.9-0.41.30.61.01.10.9-1.4-1.31.4
Bone: elastic work2.73.55.2-1.42.31.61.71.91.7-1.8-2.12.0
Bone: endosteal estimation0.51.25.3-2.30.61.00.91.21.1-0.0-0.70.1
Bone: endosteal perimeter0.20.31.4-1.2-0.20.40.40.60.50.6-0.0-0.4
Epididymis fat weight3.06.910.2-3.22.82.92.72.42.6-2.4-2.32.2
Delta time in closed arm before/after self-admin0.00.00.10.1-0.3-0.2-0.2-0.1-0.10.20.2-0.4
Delta time in open arm before/after self-admin1.51.41.7-1.21.31.11.31.31.2-1.2-1.11.1
Diff in mean of infusions in LGA sessions0.30.40.90.7-0.4-0.8-1.0-0.7-0.7-0.00.3-0.5
Delay discount exponential model param1.51.62.6-1.61.01.51.51.61.2-0.6-1.10.9
Extinction: sum of active levers before priming0.00.00.1-0.3-0.3-0.3-0.10.2-0.10.10.0-0.2
Active lever presses in extinction session 61.91.82.9-1.51.01.51.61.61.7-0.8-1.21.1
Bone: final force0.10.10.4-0.30.60.50.20.40.30.3-0.20.3
Bone: final moment0.10.10.3-0.30.60.40.10.40.30.4-0.20.2
Food consumed during 24 hour testing period0.20.30.50.0-0.4-0.5-0.7-0.6-0.60.50.4-0.7
Glucose0.30.41.4-1.20.40.70.70.60.6-0.6-0.40.3
Heart weight1.52.23.4-1.91.41.71.61.11.4-1.4-1.31.3
Delay discount hyperbolic model param1.11.22.0-1.30.81.41.31.41.1-0.4-0.90.8
Intermittent access intake day 1-15 change0.80.82.1-1.40.71.21.00.80.7-0.2-0.90.6
Intermittent access intake escalation0.40.31.3-1.10.40.80.60.60.30.1-0.60.1
Intermittent access intake escalation 20.50.51.8-1.30.60.90.60.70.4-0.1-0.60.1
Intermitt. access day 1 inactive lever presses0.60.71.20.5-0.7-0.6-0.6-1.0-1.10.71.1-0.7
Intermitt. access day 15 inactive lever presses0.10.10.6-0.80.00.40.4-0.1-0.0-0.20.3-0.3
Intermitt. access escalation Index4.84.27.3-1.81.62.42.32.42.7-1.0-2.01.7
Intermittent access day 1 total infusions0.20.30.5-0.20.50.20.60.70.6-0.0-0.60.7
Intermittent access day 15 total infusions0.50.61.0-0.90.70.81.00.90.6-0.3-0.80.7
Intermittent access terminal intake (last 3 days)0.91.01.3-0.91.00.91.20.91.0-0.7-1.11.1
Intermittent access total infusions0.91.01.6-1.10.91.01.31.01.1-0.5-1.01.1
Intermittent access day 1 locomotion0.40.41.2-0.00.80.10.60.70.6-0.2-0.91.1
Intermittent access day 15 total locomotion0.20.20.4-0.60.50.30.60.50.50.0-0.50.5
Intermittent access total locomotion0.10.10.4-0.10.4-0.10.40.00.20.0-0.60.7
Intermittent access standard deviation0.20.20.4-0.4-0.20.0-0.1-0.6-0.60.60.1-0.3
Left kidney weight0.92.64.6-2.11.52.01.61.51.6-1.1-1.41.2
Right kidney weight0.72.04.3-2.11.31.81.41.21.4-1.3-1.11.0
Cocaine induced anxiety0.10.10.30.1-0.5-0.2-0.1-0.10.50.50.3-0.3
Post-drug Anxiety0.60.61.7-1.10.60.60.90.61.3-0.5-0.30.5
Baseline Anxiety1.81.93.1-1.81.41.41.51.21.1-1.5-1.21.2
Tail length0.20.61.5-1.20.30.40.81.01.10.2-0.50.1
Length with tail0.62.04.0-2.01.21.61.81.61.8-0.2-1.00.9
Length without tail0.40.91.9-1.11.11.41.20.80.9-0.4-0.60.8
Times rat made contact with spout3.54.15.6-2.42.11.81.92.02.0-2.0-2.11.8
Lifetime Intake0.60.61.1-1.00.60.81.00.70.8-0.5-0.70.8
Liver weight, left0.10.21.20.2-0.1-0.1-0.20.0-0.11.10.3-0.4
Liver weight, right0.30.52.40.6-0.4-0.6-0.5-0.2-0.41.60.6-0.7
Locomotor activity0.30.50.8-0.90.70.70.50.70.6-0.8-0.60.7
Locomotor testing distance0.00.00.1-0.20.00.1-0.00.10.1-0.2-0.20.2
Locomotor testing rearing0.50.71.7-1.30.70.90.80.60.7-0.9-0.80.9
Locomotion in novel chamber0.60.73.20.4-1.1-0.2-0.1-0.1-0.31.80.9-1.0
Locomotion in novel chamber post-restriction1.41.73.11.1-1.6-1.0-1.0-1.2-1.11.81.4-1.2
Fecal boli incidents, locomotor time 12.22.43.91.0-1.8-1.5-1.5-1.6-1.02.01.5-1.9
Change in fecal boli incidents, locomotor task0.60.51.0-0.30.50.80.80.80.6-1.0-0.50.9
Time >=10cm from walls, locomotor time 10.40.40.90.4-0.8-0.5-0.5-0.5-0.60.00.9-0.6
Bouts of movement, locomotor time 13.03.34.41.2-2.0-2.1-2.0-1.7-1.81.81.7-1.9
Total resting periods, locomotor time 14.14.55.81.4-2.3-2.4-2.2-2.0-2.12.32.0-2.2
Rest time, locomotor task time 12.02.23.50.6-1.6-1.8-1.7-1.1-1.41.61.3-1.9
Distance moved, locomotor task time 10.30.31.51.20.2-0.2-0.4-0.7-0.5-0.5-0.10.4
Vertical activity count, locomotor time 10.40.40.8-0.40.80.60.50.50.6-0.9-0.60.7
Time >=10cm from walls, locomotor time 21.31.42.5-1.61.11.11.21.11.2-1.2-1.11.0
Bouts of movement, locomotor time 20.80.91.3-0.80.90.90.81.10.9-0.9-1.11.1
Total resting periods, locomotor time 20.90.91.3-0.90.91.00.81.11.0-0.9-1.11.1
Rest time, locomotor task time 20.10.20.30.4-0.5-0.3-0.5-0.4-0.30.30.4-0.5
Distance moved, locomotor task time 20.40.51.00.7-0.4-1.0-0.9-0.8-0.90.50.2-0.5
Vertical activity count, locomotor time 20.10.10.2-0.30.3-0.2-0.00.40.1-0.3-0.40.2
Light reinforcement 10.50.82.1-0.0-1.0-0.8-0.7-0.7-0.61.50.9-1.3
Light reinforcement 20.40.61.2-0.9-0.00.70.81.11.10.7-0.70.0
Bone: marrow area0.61.35.4-2.30.61.01.01.31.2-0.0-0.70.2
Bone: maximum diameter0.10.20.5-0.70.30.40.30.60.50.1-0.1-0.1
Bone: maximum force0.10.10.5-0.30.30.4-0.00.20.10.70.1-0.0
Bone: maximum moment0.10.10.6-0.20.30.3-0.10.20.10.80.1-0.1
Mean time between licks in bursts0.10.20.50.6-0.5-0.1-0.1-0.2-0.20.70.6-0.4
Mean num. licks in bursts1.92.23.0-1.61.41.31.51.71.6-1.0-1.71.3
Cd content in liver0.30.40.70.1-0.3-0.7-0.8-0.7-0.7-0.20.7-0.8
Co content in liver0.70.81.41.0-0.7-1.2-1.1-0.9-0.90.90.6-0.7
Cu content in liver0.70.81.10.8-1.0-0.9-1.0-0.8-0.80.90.9-1.0
Fe content in liver0.40.41.4-1.20.60.80.70.50.5-0.1-0.60.4
K content in liver1.11.12.81.7-0.2-1.2-1.0-1.2-1.21.30.3-0.2
Mg content in liver0.10.10.40.70.6-0.00.0-0.1-0.10.1-0.40.4
Mn content in liver0.60.72.51.0-1.0-0.5-0.3-0.4-0.31.60.8-0.6
Na content in liver1.11.12.5-0.41.60.90.90.90.80.0-1.51.5
Rb content in liver0.81.01.71.2-0.5-1.0-1.2-1.3-1.3-0.11.2-0.8
Se content in liver0.20.20.40.60.1-0.6-0.4-0.5-0.4-0.60.20.1
Sr content in liver0.50.51.40.4-0.9-0.5-0.5-0.5-0.51.20.6-0.8
Zn content in liver0.10.10.20.1-0.1-0.2-0.2-0.3-0.30.5-0.0-0.1
Bone: minimum diameter0.51.01.9-1.01.01.11.01.41.20.3-0.90.7
Time in familiar zone, hab. session 10.10.10.2-0.00.3-0.2-0.3-0.3-0.3-0.4-0.10.3
Time in novel zone, hab. session 10.40.40.7-0.80.20.70.80.80.8-0.5-0.30.3
Total zone transitions, hab. session 10.60.81.20.8-0.8-1.1-1.1-1.0-1.01.10.3-0.8
Total locomotion distance, hab. session 11.01.42.01.1-1.2-1.4-1.4-1.3-1.31.30.7-1.0
Locomotion velocity, hab. session 11.52.12.81.5-1.4-1.6-1.6-1.5-1.51.70.9-1.2
Time in familiar zone, hab. session 20.10.10.5-0.7-0.10.30.20.30.20.0-0.30.3
Time in novel zone, hab. session 20.20.20.4-0.30.50.30.50.50.5-0.6-0.30.2
Total zone transitions, hab. session 20.10.21.2-0.5-0.4-0.00.10.00.01.10.1-0.4
Total locomotion distance, hab. session 20.40.53.2-0.6-0.8-0.00.0-0.00.01.80.3-0.6
Locomotion velocity, hab. session 20.60.84.5-0.1-1.1-0.4-0.3-0.4-0.32.10.5-0.8
Novel to familiar place preference ratio0.20.20.30.2-0.3-0.3-0.4-0.5-0.5-0.10.6-0.5
Novelty place preference0.20.20.30.3-0.2-0.3-0.4-0.6-0.5-0.10.6-0.4
Time in novel zone, NPP test0.00.00.1-0.20.10.0-0.1-0.2-0.2-0.40.3-0.2
Total zone transitions, NPP test0.71.03.40.6-1.0-1.0-0.9-0.7-0.71.80.5-1.1
Total locomotion distance, NPP test1.21.75.60.5-1.5-1.0-1.0-0.9-0.82.41.0-1.5
Locomotion velocity, NPP test1.72.36.90.9-1.7-1.3-1.2-1.2-1.12.61.2-1.7
Intraocular pressure3.34.66.61.8-2.6-2.3-2.1-1.8-2.01.62.6-2.5
Delta distance traveled before/after self-admin0.50.50.90.30.80.80.80.70.7-0.7-0.40.9
Delta ambulatory time before/after self-admin0.30.30.50.30.50.50.70.60.6-0.6-0.20.7
Parametrial fat weight12.424.128.0-5.15.14.85.15.35.2-4.1-4.84.7
Pavlov. Cond. lever latency3.03.85.4-2.11.22.22.12.12.1-2.3-1.61.5
Pavlov. Cond. magazine entry latency0.10.10.30.20.50.10.0-0.2-0.10.0-0.20.4
Pavlov. Cond. change in total contacts3.53.75.92.4-1.3-2.2-2.1-2.2-2.21.51.9-1.4
Pavlov. Cond. index score0.91.11.91.4-0.2-1.2-1.2-1.3-1.31.20.6-0.5
Pavlov. Cond. latency score1.62.03.01.7-0.7-1.6-1.5-1.6-1.61.71.1-0.9
Pavlov. Cond. lever contacts1.71.93.31.4-0.6-1.8-1.5-1.5-1.51.80.9-1.0
Pavlov. Cond. magazine entry number0.10.10.3-0.3-0.50.10.20.40.40.10.0-0.3
Pavlov. Cond. intertrial magazine entries0.60.73.0-0.1-1.2-0.00.0-0.0-0.11.70.9-1.0
Pavlov. Cond. lever-magazine prob. diff.0.81.01.71.3-0.1-1.1-1.1-1.2-1.21.10.5-0.3
Pavlov. Cond. response bias0.50.61.11.0-0.0-0.9-0.9-1.0-1.00.80.5-0.4
Pavlov. Cond. lever latency3.04.05.52.4-2.1-2.0-2.0-1.9-1.92.21.8-1.6
Pavlov. Cond. magazine entry latency1.61.94.9-2.20.91.51.51.51.5-0.8-1.00.6
Pavlov. Cond. change in total contacts5.27.18.9-3.02.82.72.72.62.7-2.4-2.62.5
Pavlov. Cond. index score4.25.38.3-2.92.22.42.42.32.3-2.4-2.01.8
Pavlov. Cond. latency score3.13.85.9-2.41.91.92.01.91.9-2.2-1.71.5
Pavlov. Cond. lever contacts2.53.55.2-2.32.01.91.91.81.8-1.9-1.71.5
Pavlov. Cond. magazine entry number2.63.26.42.5-1.6-1.8-1.9-1.8-1.81.31.6-1.2
Pavlov. Cond. intertrial magazine entries1.31.62.91.7-1.1-1.3-1.3-1.3-1.31.31.2-0.9
Pavlov. Cond. lever-magazine prob. diff.4.65.98.5-2.92.42.52.52.42.4-2.5-2.22.0
Pavlov. Cond. response bias2.94.06.5-2.61.92.12.12.12.1-1.7-1.71.4
Time in closed arm before self-admin0.20.20.40.4-0.6-0.2-0.4-0.2-0.40.20.5-0.6
Time in closed arm after self-admin0.50.50.90.4-0.9-0.5-0.7-0.4-0.50.80.7-1.0
Time in open arm before self-admin1.21.32.5-1.01.21.11.20.71.1-1.0-1.21.6
Time in open arm after self-admin4.65.17.0-1.72.52.02.32.22.3-2.0-2.52.7
Bone: periosteal estimation0.40.92.3-1.50.80.90.81.21.10.3-0.70.4
Bone: periosteal perimeter0.20.40.8-0.90.40.60.60.90.80.6-0.50.2
Bone: post-yield work0.20.30.7-0.4-0.4-0.2-0.4-0.6-0.60.80.4-0.5
Progressive ratio test 1 active lever presses0.40.40.7-0.50.60.40.80.70.7-0.3-0.70.8
Progressive ratio test 1 breakpoint0.60.61.0-0.60.80.50.90.70.8-0.6-0.91.0
Progressive ratio test 1 inactive lever presses0.10.20.4-0.3-0.4-0.2-0.1-0.2-0.30.50.5-0.6
Progressive ratio test 2 active lever presses0.10.10.8-0.10.0-0.30.0-0.10.00.90.1-0.2
Progressive ratio test 2 breakpoint0.10.10.6-0.20.2-0.10.2-0.00.20.8-0.10.1
Progressive ratio test 2 inactive lever presses0.30.41.1-1.10.20.40.70.60.61.0-0.3-0.1
Incentive Sensitization - Responses0.30.32.6-0.2-0.10.00.30.10.31.60.1-0.3
Incentive Sensitization - Breakpoint0.40.42.2-0.40.10.30.50.40.61.5-0.1-0.1
Sum of active levers in priming session hrs 5-60.60.61.30.8-1.1-0.9-0.9-0.5-0.50.30.7-0.9
Progressive ratio0.60.71.70.5-1.3-1.1-0.7-0.7-0.50.60.9-0.8
Food seeking constrained by brief footshock0.20.20.70.8-0.1-0.8-0.5-0.2-0.3-0.2-0.50.3
Seeking ratio, punishment vs. effort1.41.63.2-0.71.81.30.81.10.8-1.4-1.81.4
Retroperitoneal fat weight8.427.732.2-5.75.75.45.45.25.3-5.0-4.84.9
Reaction time number correct1.42.04.11.0-2.0-0.9-1.2-1.4-1.20.91.9-1.7
Reaction time mean minus median2.22.95.2-2.31.71.71.81.31.7-1.5-1.41.7
Reaction time mean minus median AUC1.92.55.1-2.31.41.51.81.41.8-1.2-1.21.4
Reaction time num false alarms1.72.33.31.8-1.5-1.4-1.4-1.5-1.51.71.4-1.3
Reaction time num false alarms AUC1.52.03.01.7-1.4-1.3-1.4-1.5-1.51.31.3-1.2
Reaction time trials correct on left1.42.04.11.0-2.0-0.9-1.2-1.4-1.20.91.9-1.7
Reaction time trials on left1.31.83.90.9-2.0-0.8-1.1-1.3-1.10.91.8-1.6
Reaction time mean3.14.47.5-2.72.01.91.92.12.0-2.3-1.91.8
Reaction time mean AUC3.04.16.3-2.52.01.91.92.02.0-2.1-1.91.9
Median of all reaction times2.63.65.9-2.41.81.71.62.01.7-2.2-1.81.6
Reaction time omissions0.71.01.9-1.40.71.21.21.11.1-0.6-0.50.7
Reaction time false alarm rate0.40.51.11.0-0.4-0.8-0.7-0.7-0.80.90.3-0.4
Reaction time premature initiation rate0.20.20.40.5-0.4-0.7-0.5-0.5-0.40.30.4-0.5
Reaction time premature initiations1.01.42.21.0-1.5-1.2-1.1-1.2-1.10.71.3-1.4
Std. dev. reaction times2.23.15.4-2.31.81.61.71.61.8-1.7-1.61.6
Reaction time trials completed1.31.83.90.9-2.0-0.8-1.1-1.3-1.10.91.8-1.6
Reaction time trials AUC1.52.14.50.8-2.1-0.8-1.1-1.3-1.21.12.0-1.8
Run reversals in cocaine runway, females3.02.94.6-2.11.71.81.91.81.8-0.7-1.61.6
Run reversals in cocaine runway, males1.11.12.4-0.71.61.11.10.60.6-1.0-0.81.5
Latency to leave start box in cocaine runway0.30.30.7-0.2-0.20.70.60.80.80.3-0.10.3
Latency to leave start box in cocaine runway, F0.10.10.3-0.5-0.20.50.30.30.30.20.3-0.1
Latency to leave start box in cocaine runway, M0.80.81.70.20.40.80.91.31.20.1-1.11.0
Std. dev. time between licks in bursts1.21.41.71.3-1.2-1.2-1.0-1.1-1.11.31.3-1.2
Total sessions with >9 infusions1.21.32.4-1.41.11.01.50.81.0-0.9-0.91.4
Short access day 1 total inactive lever presses0.80.92.3-0.4-1.3-0.3-0.2-0.8-0.51.51.2-1.2
Short access day 10 total inactive lever presses0.20.20.7-0.8-0.00.60.40.30.3-0.40.1-0.2
Short access day 1 total infusions0.20.20.4-0.3-0.6-0.4-0.1-0.5-0.30.60.4-0.5
Short access day 10 total infusions0.30.40.7-0.70.50.40.80.60.6-0.6-0.50.7
Short access total infusions0.80.91.5-1.20.80.81.20.90.9-0.8-0.91.0
Short access day 1 locomotion1.11.21.9-1.41.10.91.30.91.1-0.9-1.01.2
Short access day 10 total locomotion1.11.22.50.7-0.9-1.6-1.1-1.2-1.21.10.9-0.9
Short access total locomotion0.50.51.5-0.60.80.20.90.40.7-0.4-0.81.2
One hour access (0.3 mA shock)0.10.10.7-0.1-0.3-0.2-0.10.3-0.10.9-0.0-0.3
Compulsive drug intake0.60.62.10.2-1.0-0.4-0.80.1-0.21.40.5-1.0
One hour access (shock baseline)0.10.10.3-0.30.60.30.40.10.1-0.5-0.30.5
Social response proportion6.97.58.4-2.62.72.52.92.82.8-2.8-2.72.8
Social responses0.10.20.8-0.30.40.20.30.10.2-0.9-0.20.4
Social time1.31.82.3-1.11.31.41.41.41.4-1.5-1.21.3
Soleus weight0.10.20.9-0.3-0.2-0.0-0.1-0.1-0.10.90.3-0.6
Bone: stiffness0.10.21.20.0-0.30.3-0.3-0.1-0.11.10.7-0.4
Tibialis anterior weight0.41.43.1-1.81.41.31.11.21.3-0.4-1.20.8
Time to tail flick, vehicle, before self-admin2.02.03.4-1.80.91.61.81.51.5-1.3-1.01.2
Time to tail flick, vehicle, after self-admin2.72.94.21.7-1.5-1.7-2.1-2.0-1.80.71.7-1.7
Time to tail flick, test, before self-admin0.30.30.70.4-0.6-0.8-0.7-0.3-0.70.10.2-0.6
Time to tail flick, test, after self-admin1.01.02.3-0.0-1.4-0.6-0.7-0.6-0.81.01.3-1.5
Delta time to tail flick, vehicle, before/after SA6.86.89.12.7-2.2-2.5-3.0-2.8-2.81.92.5-2.7
Delta time to tail flick, test, before/after SA0.30.30.9-0.2-0.6-0.0-0.1-0.2-0.11.00.7-0.8
Tibia length1.85.16.4-2.32.52.02.42.42.4-1.5-2.22.4
Ambulatory time before self-admin0.10.10.5-0.30.40.40.00.10.2-0.7-0.50.3
Ambulatory time after self-admin0.20.20.40.50.50.40.20.20.3-0.7-0.40.5
Bone: tissue strength1.00.91.7-1.31.20.80.81.00.9-0.4-1.11.0
Total heroin consumption0.20.20.5-0.5-0.5-0.00.50.60.70.3-0.10.0
Bone: trabecular number0.30.41.40.8-0.4-0.6-0.6-0.4-0.41.20.6-0.5
Bone: trabecular spacing0.91.23.9-0.71.20.90.80.70.8-2.0-0.91.1
Bone: trabecular thickness0.10.10.40.4-0.3-0.3-0.4-0.1-0.20.70.2-0.4
Bone: trabecular tissue density0.20.31.0-0.41.00.60.30.30.3-0.3-0.70.7
Water consumed over 24 hours0.10.11.0-1.0-0.00.20.00.20.30.1-0.1-0.1
Number of responses in last shaping day1.11.21.80.2-1.0-1.1-1.2-1.3-1.10.61.2-1.3