Hub : Genes

Scp2d1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression Scp2d1 0.11 0.05 3.2e-05 0.07 0.11 0.09 0.09 5.6e-04 1.8e-05 1.0e-04 1.3e-04
2 NAcc gene expression Scp2d1 0.15 0.05 0.0e+00 0.2 0.12 0.2 0.2 4.1e-30 2.4e-18 1.9e-29 9.9e-30
3 IL gene expression Scp2d1 0.27 0.13 8.3e-04 0.13 0.06 0.08 0.07 4.7e-04 1.4e-02 5.2e-03 8.4e-03
4 BLA gene expression Scp2d1 0.27 0.11 4.4e-09 0.17 0.16 0.17 0.17 2.7e-09 4.7e-09 3.3e-09 3.7e-09
5 Brain gene expression Scp2d1 0.2 0.07 0.0e+00 0.27 0.24 0.25 0.26 1.4e-25 7.7e-22 3.6e-23 1.9e-24
6 PL gene expression Scp2d1 0.22 0.07 0.0e+00 0.21 0.21 0.21 0.21 1.1e-22 9.8e-23 3.1e-22 9.2e-23
7 RMTg gene expression Scp2d1 0.17 0.08 3.7e-04 0.12 0.03 0.05 0.08 3.7e-04 7.3e-02 1.7e-02 4.3e-03
8 pVTA gene expression Scp2d1 0.09 0.04 1.2e-06 0.09 0.08 0.09 0.09 5.3e-08 4.1e-07 1.2e-07 1.3e-07
9 LHb gene expression Scp2d1 0.35 0.13 3.6e-06 0.18 0.11 0.14 0.04 4.5e-05 1.6e-03 4.1e-04 3.9e-02
10 OFC gene expression Scp2d1 0.4 0.15 2.3e-05 0.16 0.13 0.14 0.1 1.5e-04 5.4e-04 3.8e-04 2.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.30.50.70.70.30.60.60.60.50.50.60.5
Area under the delay curve1.01.22.70.81.60.91.11.11.01.31.30.80.6
BMI with tail6.723.030.0-5.5-5.1-5.3-4.7-4.7-4.8-3.9-3.9-4.9-4.9
BMI without tail5.717.422.3-4.7-4.6-4.3-4.3-4.3-4.3-3.5-3.5-4.0-4.0
Body weight5.825.534.2-5.8-5.5-5.5-5.2-5.3-5.0-4.3-4.3-4.7-4.7
Weight adjusted by age1.01.62.71.30.71.11.20.81.11.71.71.41.2
Bone surface0.61.01.5-0.7-0.9-0.8-1.1-1.0-1.0-1.2-1.2-1.0-1.1
Bone volume0.00.00.10.2-0.00.0-0.2-0.20.0-0.3-0.30.1-0.0
Breakpoint value in progressive ratio session1.72.03.1-1.3-1.3-0.7-1.8-1.8-1.7-1.5-1.5-1.1-1.2
Number of licking bursts0.20.30.70.00.50.20.50.40.40.90.90.50.5
Context. condit. distance diff. score0.00.00.10.2-0.30.0-0.2-0.20.1-0.1-0.10.20.1
Locomotion velocity, session 10.30.30.70.5-0.30.9-0.5-0.4-0.3-0.7-0.7-0.2-0.2
Locomotion distance, session 12.73.45.32.02.02.31.92.01.91.41.41.61.5
Locomotion velocity, session 20.50.61.81.01.31.00.90.90.70.20.20.40.3
Locomotion distance, session 23.04.28.62.42.02.91.71.82.01.21.22.32.3
Locomotion velocity, session 32.12.43.31.81.61.71.51.61.61.51.51.41.4
Locomotion distance, session 30.91.01.31.11.11.01.01.01.10.90.90.90.9
Stereotopy head waving bouts, day 30.10.10.2-0.3-0.4-0.0-0.3-0.3-0.4-0.3-0.3-0.3-0.2
Stereotopy head waving duration, day 30.30.30.5-0.5-0.7-0.3-0.7-0.7-0.7-0.5-0.5-0.5-0.5
Locomotion velocity, session 72.12.32.61.61.51.51.51.41.51.51.51.61.6
Locomotion distance, session 70.91.11.60.90.91.20.90.91.11.01.01.31.3
Stereotopy head waving bouts, day 70.00.00.1-0.3-0.1-0.2-0.1-0.1-0.2-0.1-0.1-0.2-0.1
Stereotopy head waving duration, day 70.00.00.00.2-0.00.1-0.00.1-0.0-0.1-0.1-0.00.1
Locomotion velocity, session 80.20.21.00.70.11.0-0.0-0.10.1-0.5-0.50.30.3
Locomotion distance, session 81.92.84.82.01.52.21.41.41.71.21.21.81.7
Degree of sensitization distance0.00.00.1-0.3-0.20.1-0.1-0.20.0-0.1-0.10.20.3
Degree of sensitization stereotypy0.20.30.4-0.5-0.5-0.4-0.6-0.6-0.5-0.5-0.5-0.4-0.4
Conditioned locomotion0.10.10.40.4-0.30.5-0.6-0.5-0.2-0.0-0.00.30.3
Cocaine response after cond. corrected3.13.74.41.71.82.02.01.92.01.81.82.12.1
Cocaine response after cond. not corrected5.56.47.62.42.42.62.52.52.72.32.32.72.8
Cocaine response before conditioning0.30.30.70.80.60.40.40.60.70.20.20.60.6
Saline control response0.50.71.7-0.2-1.10.4-1.0-0.9-0.5-1.3-1.30.10.2
Bone: connectivity density0.00.00.10.40.4-0.10.20.30.1-0.0-0.0-0.0-0.1
Bone: cortical apparent density0.20.20.50.30.3-0.70.30.10.00.60.6-0.5-0.5
Bone: cortical area0.20.30.9-0.1-0.3-0.9-0.1-0.1-0.30.00.0-0.9-0.9
Bone: cortical porosity0.91.01.4-0.9-0.9-0.8-0.9-0.8-1.1-1.0-1.0-1.2-1.2
Bone: cortical porosity1.11.21.7-1.0-1.1-0.9-1.1-1.0-1.2-1.1-1.1-1.3-1.3
Bone: cortical thickness0.61.02.9-0.3-0.5-1.7-0.5-0.5-0.8-0.1-0.1-1.7-1.6
Bone: cortical thickness1.11.32.71.11.30.41.21.31.11.61.60.40.4
Bone: cortical tissue density0.10.20.40.30.3-0.60.30.10.00.60.6-0.5-0.4
Condit. Reinf. active minus inactive responses0.30.30.90.30.50.50.50.40.50.10.10.91.0
Condit. Reinf. active-inactive response ratio0.50.51.20.40.60.70.60.50.70.70.71.01.1
Condit. Reinf. active responses0.30.30.80.40.60.60.50.50.60.10.10.90.9
Condit. Reinf. inactive responses0.10.10.3-0.0-0.1-0.1-0.2-0.2-0.2-0.6-0.6-0.2-0.2
Incentive salience index mean0.60.71.30.61.10.61.11.11.00.60.60.80.8
Condit. Reinf. lever presses0.60.81.90.41.30.21.41.41.00.70.70.30.2
Condit. Reinf. active minus inactive responses1.62.03.2-1.1-1.8-1.1-1.7-1.6-1.5-1.5-1.5-1.2-1.2
Condit. Reinf. active-inactive response ratio1.11.31.9-1.2-1.2-0.8-1.4-1.3-1.2-1.3-1.3-0.8-0.8
Condit. Reinf. active responses1.42.02.8-1.0-1.7-1.5-1.4-1.3-1.4-1.1-1.1-1.7-1.6
Condit. Reinf. inactive responses0.60.72.2-0.3-0.8-1.3-0.4-0.4-0.7-0.2-0.2-1.5-1.3
Condit. Reinf. lever presses3.75.16.7-2.0-2.6-1.9-2.5-2.4-2.3-2.6-2.6-1.8-1.7
Condit. Reinf. lever reinforcers received2.12.94.0-1.3-2.0-1.7-1.8-1.7-1.8-1.6-1.6-1.9-1.8
Conditioned reinforcement - actives0.61.02.91.00.61.7-0.20.60.8-0.3-0.31.61.5
Conditioned reinforcement - inactives1.01.53.51.30.61.70.60.71.20.80.81.91.8
Conditioned locomotion0.00.10.10.30.20.2-0.10.20.1-0.3-0.30.3-0.0
Patch foraging indifference point 0 sec0.81.42.21.20.31.21.10.91.21.41.41.31.5
Patch foraging indifference point AUC0.10.10.50.50.70.30.30.30.20.40.40.00.1
Delay disc. indifference point, 0s delay0.30.40.6-0.80.1-0.4-0.6-0.5-0.6-0.6-0.6-0.6-0.8
Delay disc. indifference point, 16s delay1.51.72.61.11.61.21.31.51.21.31.31.11.1
Delay disc. indifference point, 2s delay0.10.10.5-0.70.4-0.30.30.0-0.2-0.2-0.2-0.3-0.3
Delay disc. indifference point, 24s delay5.66.38.52.42.92.52.32.62.72.62.62.32.1
Delay disc. indifference point, 4s delay0.20.20.8-0.10.9-0.00.50.50.40.70.70.20.0
Delay disc. indifference point, 8s delay0.40.51.20.91.10.80.50.40.60.80.80.60.3
Indifference point function ln k0.10.20.40.6-0.00.40.40.50.60.30.30.50.6
Indifference point function log k0.10.20.40.6-0.00.40.40.50.60.30.30.50.6
Patch foraging total patch changes 0 sec0.81.52.21.30.41.41.10.91.21.41.41.31.5
Patch foraging total patch changes 12 sec0.10.10.30.1-0.10.00.3-0.10.00.60.6-0.3-0.1
Patch foraging total patch changes 18 sec1.11.72.41.51.01.41.10.91.11.51.51.31.4
Patch foraging total patch changes 24 sec0.20.30.60.40.30.80.70.50.60.70.70.50.4
Patch foraging total patch changes 6 sec1.11.72.51.10.81.11.41.21.41.61.61.21.3
Patch foraging time to switch 0 sec0.81.52.6-1.6-1.0-1.6-1.0-1.1-1.2-1.1-1.1-1.2-1.2
Patch foraging water rate 0 sec1.42.84.11.91.51.61.71.61.52.02.01.41.4
Patch foraging water rate 12 sec2.65.37.12.52.72.12.32.52.42.42.41.91.9
Patch foraging water rate 18 sec10.516.218.74.14.14.34.04.14.23.83.84.03.8
Patch foraging water rate 24 sec4.96.89.42.52.53.12.22.22.52.62.62.92.8
Patch foraging water rate 6 sec4.16.08.32.92.32.62.22.32.52.62.62.12.2
Seeking ratio, delayed vs. immediate footshock0.60.71.2-1.0-1.1-0.6-0.7-0.6-0.7-0.9-0.9-0.9-0.6
Distance traveled before self-admin0.10.10.4-0.60.1-0.7-0.2-0.0-0.30.00.0-0.4-0.6
Distance traveled after self-admin0.20.20.70.1-0.1-0.80.0-0.2-0.30.50.5-0.6-0.8
Extensor digitorum longus weight0.00.20.4-0.1-0.50.0-0.5-0.6-0.3-0.6-0.6-0.0-0.1
Bone: elastic displacement1.51.72.4-1.2-1.0-1.1-1.4-1.3-1.3-1.2-1.2-1.5-1.6
Bone: elastic work2.83.75.1-2.1-1.8-2.0-1.8-1.8-1.9-1.6-1.6-2.3-2.3
Bone: endosteal estimation0.40.81.7-1.2-1.20.1-0.9-0.9-0.6-1.3-1.30.10.0
Bone: endosteal perimeter0.10.20.5-0.1-0.40.7-0.3-0.20.0-0.6-0.60.50.5
Epididymis fat weight6.522.326.2-5.1-5.1-4.7-4.8-5.0-4.7-4.7-4.7-4.2-4.0
Delta time in closed arm before/after self-admin0.30.30.50.50.60.20.70.40.50.50.50.70.7
Delta time in open arm before/after self-admin2.22.22.7-1.6-1.5-1.5-1.6-1.5-1.5-1.5-1.5-1.2-1.3
Diff in mean of infusions in LGA sessions0.10.10.4-0.50.4-0.6-0.10.2-0.2-0.2-0.2-0.5-0.5
Delay discount exponential model param1.41.63.3-1.0-1.8-1.0-1.3-1.3-1.2-1.4-1.4-1.0-0.8
Extinction: sum of active levers before priming0.10.10.30.20.30.4-0.3-0.10.0-0.2-0.20.60.4
Active lever presses in extinction session 63.63.64.4-1.6-2.1-1.6-2.1-1.9-2.0-1.9-1.9-1.9-1.8
Bone: final force0.00.10.2-0.2-0.3-0.40.10.00.00.20.2-0.4-0.4
Bone: final moment0.00.10.2-0.1-0.3-0.30.10.10.10.20.2-0.4-0.4
Food consumed during 24 hour testing period0.20.30.80.10.70.30.70.90.80.40.40.60.6
Glucose1.01.62.7-1.1-1.4-0.8-1.4-1.5-1.3-1.6-1.6-0.8-0.8
Heart weight1.32.03.1-1.3-1.8-1.2-1.3-1.4-1.5-1.3-1.3-1.4-1.3
Delay discount hyperbolic model param0.91.02.3-0.6-1.5-0.7-1.1-1.0-0.9-1.1-1.1-0.8-0.5
Intermittent access intake day 1-15 change0.30.71.2-1.0-1.1-0.7-0.7-0.8-0.8-1.0-1.0-0.6-0.5
Intermittent access intake escalation0.20.40.7-0.8-0.9-0.5-0.4-0.5-0.6-0.8-0.8-0.5-0.4
Intermittent access intake escalation 20.30.31.0-1.0-0.8-0.7-0.4-0.3-0.4-0.6-0.6-0.3-0.2
Intermitt. access day 1 inactive lever presses0.31.01.61.20.81.21.00.81.10.80.81.11.3
Intermitt. access day 15 inactive lever presses0.10.10.50.0-0.7-0.0-0.1-0.3-0.00.10.10.50.6
Intermitt. access escalation Index1.92.74.0-0.8-1.5-1.1-2.0-1.9-1.7-2.0-2.0-1.4-1.3
Intermittent access day 1 total infusions0.20.30.7-0.1-0.3-0.3-0.8-0.6-0.4-0.5-0.5-0.6-0.8
Intermittent access day 15 total infusions0.60.91.2-0.8-1.1-0.9-1.0-0.9-0.9-0.9-0.9-0.9-1.0
Intermittent access terminal intake (last 3 days)1.01.31.8-1.1-1.2-1.1-1.2-1.1-1.2-1.1-1.1-1.3-1.3
Intermittent access total infusions1.11.41.7-1.0-1.3-1.0-1.3-1.2-1.2-1.2-1.2-1.1-1.2
Intermittent access day 1 locomotion0.10.10.40.20.4-0.1-0.30.1-0.1-0.3-0.3-0.4-0.7
Intermittent access day 15 total locomotion0.61.22.0-0.9-0.9-0.8-1.1-1.2-1.1-1.4-1.4-0.7-0.9
Intermittent access total locomotion0.20.30.6-0.3-0.2-0.3-0.5-0.5-0.5-0.7-0.7-0.5-0.7
Intermittent access standard deviation0.00.00.2-0.2-0.2-0.10.40.40.10.10.10.0-0.2
Left kidney weight1.36.07.0-2.4-2.6-2.2-2.6-2.6-2.5-2.6-2.6-2.2-2.1
Right kidney weight0.52.12.7-1.5-1.5-1.1-1.4-1.6-1.6-1.6-1.6-1.2-1.1
Cocaine induced anxiety0.10.20.50.4-0.50.1-0.2-0.7-0.6-0.3-0.3-0.3-0.3
Post-drug Anxiety0.30.30.5-0.4-0.6-0.6-0.5-0.6-0.7-0.3-0.3-0.5-0.6
Baseline Anxiety0.60.72.4-1.5-0.7-1.3-0.8-0.5-0.5-0.4-0.4-0.8-0.7
Tail length0.10.51.0-0.8-1.0-0.6-0.7-1.0-0.8-0.4-0.4-0.4-0.5
Length with tail0.83.45.3-2.0-2.1-1.7-2.0-2.3-1.9-1.8-1.8-1.2-1.2
Length without tail0.72.43.2-1.7-1.8-1.8-1.4-1.7-1.5-1.5-1.5-1.3-1.2
Times rat made contact with spout3.64.25.8-2.3-1.9-1.8-2.1-2.1-2.1-2.4-2.4-1.5-1.6
Lifetime Intake0.81.01.3-0.9-1.1-0.7-1.2-1.0-1.0-1.0-1.0-0.8-1.0
Liver weight, left0.40.71.4-0.9-1.2-0.6-1.0-1.1-0.9-0.6-0.6-0.4-0.4
Liver weight, right0.61.01.6-1.2-1.3-0.9-1.2-1.1-0.9-1.0-1.0-0.7-0.7
Locomotor activity0.20.30.6-0.8-0.6-0.4-0.5-0.6-0.6-0.5-0.5-0.5-0.5
Locomotor testing distance0.00.00.1-0.3-0.1-0.10.2-0.1-0.3-0.1-0.1-0.2-0.2
Locomotor testing rearing0.30.61.1-1.0-0.8-0.5-0.4-0.8-1.0-0.8-0.8-0.5-0.6
Locomotion in novel chamber0.60.82.21.50.41.10.50.20.70.70.71.01.1
Locomotion in novel chamber post-restriction1.32.23.21.81.01.81.41.41.51.51.51.31.4
Fecal boli incidents, locomotor time 11.62.33.91.61.32.01.51.01.31.31.31.81.8
Change in fecal boli incidents, locomotor task0.50.40.7-0.3-0.7-0.6-0.9-0.4-0.6-0.8-0.8-0.7-0.8
Time >=10cm from walls, locomotor time 10.30.30.50.60.50.50.30.70.60.20.20.60.7
Bouts of movement, locomotor time 13.64.05.51.62.22.31.61.91.91.81.82.32.3
Total resting periods, locomotor time 14.55.07.01.92.42.61.82.12.21.91.92.62.6
Rest time, locomotor task time 11.82.34.81.11.72.10.61.31.50.70.72.22.1
Distance moved, locomotor task time 10.20.40.90.20.2-0.80.90.4-0.10.40.4-0.9-0.8
Vertical activity count, locomotor time 10.20.61.1-0.7-0.6-1.1-0.3-0.4-0.8-0.7-0.7-0.9-0.9
Time >=10cm from walls, locomotor time 20.91.32.2-1.2-1.1-0.7-1.3-1.1-1.0-1.5-1.5-0.9-0.8
Bouts of movement, locomotor time 20.50.81.1-0.9-0.6-0.7-1.1-0.8-1.0-0.9-0.9-0.9-0.9
Total resting periods, locomotor time 20.50.81.3-0.9-0.7-0.8-1.1-1.0-1.0-0.9-0.9-0.9-0.9
Rest time, locomotor task time 20.20.30.50.40.70.60.30.30.40.60.60.70.7
Distance moved, locomotor task time 20.30.30.90.40.70.30.90.90.60.30.30.20.3
Vertical activity count, locomotor time 20.10.20.5-0.3-0.1-0.2-0.3-0.0-0.2-0.7-0.7-0.4-0.3
Light reinforcement 10.30.82.00.70.51.40.60.40.80.60.61.41.4
Light reinforcement 20.50.71.70.2-0.80.7-1.3-1.3-0.8-0.9-0.90.30.2
Bone: marrow area0.40.91.8-1.2-1.20.1-0.9-0.9-0.7-1.4-1.40.0-0.0
Bone: maximum diameter0.00.10.2-0.4-0.4-0.2-0.3-0.1-0.0-0.4-0.40.00.1
Bone: maximum force0.00.10.20.0-0.1-0.30.40.30.20.40.4-0.1-0.2
Bone: maximum moment0.00.10.20.1-0.1-0.20.40.40.30.30.3-0.1-0.2
Mean time between licks in bursts0.10.20.60.80.20.50.40.40.50.60.60.20.3
Mean num. licks in bursts1.32.03.9-1.2-1.3-1.0-1.4-1.3-1.3-2.0-2.0-1.2-1.2
Cd content in liver1.61.82.80.71.61.11.21.31.51.21.21.71.6
Co content in liver0.40.40.80.80.60.90.40.40.60.70.70.70.7
Cu content in liver1.11.32.11.01.20.91.11.21.11.51.50.90.9
Fe content in liver1.21.42.2-1.5-1.1-1.5-0.9-0.9-1.2-1.2-1.2-1.3-1.2
K content in liver0.60.61.00.90.70.20.81.00.71.01.0-0.5-0.4
Mg content in liver0.20.20.7-0.1-0.5-0.4-0.3-0.3-0.30.10.1-0.8-0.7
Mn content in liver0.30.31.11.1-0.50.8-0.5-0.6-0.20.00.00.00.0
Na content in liver2.12.34.4-1.0-1.3-1.8-1.1-1.1-1.5-1.3-1.3-2.1-2.0
Rb content in liver0.30.41.0-0.10.50.10.80.70.61.01.00.30.3
Se content in liver0.10.20.5-0.40.0-0.50.10.2-0.00.20.2-0.7-0.7
Sr content in liver0.60.51.11.00.50.90.50.50.70.60.60.90.9
Zn content in liver0.30.30.70.40.70.40.70.80.60.60.60.10.2
Bone: minimum diameter0.40.71.0-0.6-1.0-0.9-0.8-0.7-0.8-0.8-0.8-0.9-0.9
Time in familiar zone, hab. session 10.10.10.3-0.50.4-0.40.10.2-0.1-0.1-0.1-0.3-0.2
Time in novel zone, hab. session 10.30.30.8-0.3-0.90.0-0.6-0.7-0.5-0.6-0.6-0.0-0.1
Total zone transitions, hab. session 10.50.61.40.71.21.00.80.90.70.40.40.80.8
Total locomotion distance, hab. session 10.91.22.21.11.51.21.21.31.00.80.81.01.0
Locomotion velocity, hab. session 11.21.72.71.41.61.41.41.51.31.11.11.11.0
Time in familiar zone, hab. session 20.20.20.6-0.2-0.30.2-0.4-0.4-0.4-0.8-0.80.00.0
Time in novel zone, hab. session 20.10.10.2-0.5-0.4-0.4-0.4-0.4-0.2-0.2-0.2-0.3-0.3
Total zone transitions, hab. session 20.10.20.50.2-0.10.7-0.1-0.00.1-0.6-0.60.40.4
Total locomotion distance, hab. session 20.30.41.40.7-0.01.2-0.10.00.2-0.7-0.70.80.7
Locomotion velocity, hab. session 20.40.51.91.10.31.40.20.40.5-0.3-0.30.90.8
Novel to familiar place preference ratio0.20.20.40.10.40.20.50.50.50.60.60.50.6
Novelty place preference0.20.20.50.10.40.20.50.50.50.70.70.50.5
Time in novel zone, NPP test0.10.10.1-0.30.1-0.00.20.20.20.30.30.30.4
Total zone transitions, NPP test0.50.71.31.01.01.20.60.70.80.20.21.00.9
Total locomotion distance, NPP test1.01.33.01.41.01.70.80.91.10.10.11.61.5
Locomotion velocity, NPP test1.31.83.61.71.31.91.11.21.30.50.51.71.6
Intraocular pressure2.84.17.01.91.92.71.61.52.11.61.62.52.4
Delta distance traveled before/after self-admin0.10.10.30.6-0.3-0.20.1-0.2-0.10.40.4-0.5-0.5
Delta ambulatory time before/after self-admin0.10.10.30.5-0.3-0.10.0-0.2-0.00.60.6-0.3-0.2
Parametrial fat weight16.438.547.4-6.9-6.4-5.7-6.8-6.6-6.4-6.3-6.3-5.2-5.2
Pavlov. Cond. lever latency2.32.95.1-1.4-2.1-0.9-2.2-2.3-1.9-1.9-1.9-0.8-0.8
Pavlov. Cond. magazine entry latency0.30.31.3-0.5-0.2-1.1-0.00.0-0.4-0.2-0.2-0.9-0.8
Pavlov. Cond. change in total contacts3.13.35.41.52.00.62.32.31.92.32.30.80.8
Pavlov. Cond. index score0.70.91.90.61.2-0.31.31.40.91.11.1-0.1-0.0
Pavlov. Cond. latency score1.21.53.01.01.60.21.71.71.31.51.50.30.4
Pavlov. Cond. lever contacts1.31.53.20.81.60.41.71.81.41.31.30.30.4
Pavlov. Cond. magazine entry number0.20.20.70.2-0.30.8-0.4-0.5-0.1-0.4-0.40.50.4
Pavlov. Cond. intertrial magazine entries0.60.72.41.2-0.11.5-0.00.00.50.10.11.31.3
Pavlov. Cond. lever-magazine prob. diff.0.70.92.00.41.2-0.61.41.40.81.11.1-0.3-0.2
Pavlov. Cond. response bias0.50.61.20.20.9-0.51.11.10.70.90.9-0.2-0.1
Pavlov. Cond. lever latency2.53.54.82.21.92.01.91.81.82.02.01.61.4
Pavlov. Cond. magazine entry latency1.51.82.9-1.3-1.6-0.8-1.6-1.6-1.3-1.7-1.7-0.5-0.5
Pavlov. Cond. change in total contacts4.57.28.4-2.8-2.8-2.6-2.7-2.5-2.6-2.9-2.9-2.5-2.3
Pavlov. Cond. index score3.64.86.0-2.4-2.4-2.0-2.4-2.3-2.2-2.5-2.5-1.6-1.4
Pavlov. Cond. latency score2.83.74.9-2.2-2.1-1.8-2.1-2.0-1.9-2.1-2.1-1.5-1.3
Pavlov. Cond. lever contacts2.94.05.3-2.3-2.1-2.0-2.1-1.9-1.9-2.2-2.2-1.6-1.4
Pavlov. Cond. magazine entry number2.53.04.11.82.01.51.91.91.82.02.01.11.0
Pavlov. Cond. intertrial magazine entries1.01.52.21.31.30.91.41.41.31.51.50.80.7
Pavlov. Cond. lever-magazine prob. diff.4.45.86.9-2.6-2.5-2.3-2.6-2.5-2.4-2.6-2.6-1.9-1.8
Pavlov. Cond. response bias3.04.15.6-2.2-2.4-1.9-2.3-2.1-2.0-2.3-2.3-1.5-1.3
Time in closed arm before self-admin0.00.00.20.40.1-0.10.10.30.20.20.20.20.2
Time in closed arm after self-admin0.70.71.21.10.80.30.80.80.90.70.71.01.1
Time in open arm before self-admin0.60.60.9-0.8-0.7-0.2-0.7-0.8-0.7-0.9-0.9-0.9-1.0
Time in open arm after self-admin4.04.45.4-2.0-1.9-1.8-2.2-2.2-2.1-2.0-2.0-2.2-2.3
Bone: periosteal estimation0.30.61.1-0.9-1.0-0.4-0.8-0.7-0.7-0.9-0.9-0.5-0.5
Bone: periosteal perimeter0.10.20.5-0.3-0.6-0.2-0.5-0.5-0.4-0.7-0.7-0.3-0.4
Bone: post-yield work0.20.30.70.20.30.50.70.60.50.20.20.80.8
Progressive ratio test 1 active lever presses0.81.01.3-1.0-0.8-0.7-1.1-1.0-1.0-1.1-1.1-0.9-1.1
Progressive ratio test 1 breakpoint0.70.91.1-1.0-0.7-0.6-1.1-0.9-0.9-1.1-1.1-0.9-1.0
Progressive ratio test 1 inactive lever presses0.20.31.00.20.11.00.1-0.00.50.30.30.91.0
Progressive ratio test 2 active lever presses0.30.30.5-0.5-0.5-0.2-0.7-0.7-0.5-0.7-0.7-0.4-0.5
Progressive ratio test 2 breakpoint0.40.40.6-0.6-0.7-0.2-0.7-0.8-0.6-0.8-0.8-0.5-0.6
Progressive ratio test 2 inactive lever presses0.61.02.1-0.7-1.4-0.1-1.4-1.4-0.8-1.2-1.2-0.0-0.3
Incentive Sensitization - Responses0.20.30.6-0.0-0.70.3-0.7-0.8-0.3-0.7-0.70.0-0.1
Incentive Sensitization - Breakpoint0.40.51.1-0.2-0.90.0-0.9-1.1-0.6-1.0-1.0-0.2-0.3
Sum of active levers in priming session hrs 5-60.30.21.10.40.51.1-0.10.10.10.00.00.70.6
Progressive ratio0.71.13.51.00.71.90.70.40.60.60.61.41.4
Food seeking constrained by brief footshock0.10.10.20.30.40.40.50.30.00.00.0-0.5-0.2
Seeking ratio, punishment vs. effort1.42.14.1-1.4-1.0-2.0-1.1-0.8-1.1-1.3-1.3-2.0-1.8
Retroperitoneal fat weight13.557.777.8-8.8-7.7-8.0-7.8-7.7-7.6-7.2-7.2-6.9-6.8
Reaction time number correct1.22.44.01.51.11.91.11.21.31.51.52.02.0
Reaction time mean minus median1.22.93.8-2.0-1.9-1.5-1.7-1.7-1.7-1.8-1.8-1.6-1.5
Reaction time mean minus median AUC1.02.43.1-1.7-1.8-1.2-1.7-1.7-1.6-1.7-1.7-1.3-1.2
Reaction time num false alarms1.82.64.02.01.61.41.61.61.61.71.71.41.3
Reaction time num false alarms AUC1.52.43.31.81.61.31.61.61.51.71.71.31.3
Reaction time trials correct on left1.22.44.01.51.11.91.11.21.31.51.52.02.0
Reaction time trials on left1.22.23.91.51.01.91.01.11.31.41.42.01.9
Reaction time mean2.94.67.1-2.5-2.0-1.7-2.4-2.0-2.0-2.7-2.7-1.6-1.6
Reaction time mean AUC2.74.36.5-2.3-2.0-1.7-2.3-2.0-2.0-2.6-2.6-1.7-1.7
Median of all reaction times2.63.76.3-2.2-1.7-1.5-2.2-1.8-1.8-2.5-2.5-1.3-1.3
Reaction time omissions0.60.91.9-0.8-1.2-0.5-1.4-1.2-1.0-1.0-1.0-0.4-0.6
Reaction time false alarm rate0.40.51.01.00.90.40.80.90.80.70.70.40.3
Reaction time premature initiation rate0.30.40.60.50.50.60.80.70.80.50.50.50.6
Reaction time premature initiations1.01.82.51.31.01.51.31.21.41.21.21.51.6
Std. dev. reaction times1.73.14.2-2.1-1.7-1.5-1.9-1.7-1.7-2.0-2.0-1.5-1.4
Reaction time trials completed1.22.23.91.51.01.91.01.11.31.41.42.01.9
Reaction time trials AUC1.42.74.81.61.12.11.11.21.41.41.42.22.2
Run reversals in cocaine runway, females3.33.33.7-1.8-1.9-1.6-1.8-1.7-1.8-1.8-1.8-1.8-1.8
Run reversals in cocaine runway, males1.21.23.1-1.3-1.0-1.8-0.4-0.3-0.8-0.2-0.2-1.7-1.7
Latency to leave start box in cocaine runway0.20.20.50.4-0.70.0-0.4-0.7-0.4-0.4-0.4-0.1-0.2
Latency to leave start box in cocaine runway, F0.10.10.20.1-0.40.1-0.3-0.2-0.0-0.4-0.40.20.1
Latency to leave start box in cocaine runway, M0.40.41.30.7-0.9-0.1-0.3-1.1-0.8-0.3-0.3-0.5-0.5
Std. dev. time between licks in bursts0.81.11.51.21.01.10.90.91.11.21.20.90.9
Total sessions with >9 infusions1.11.41.9-1.3-1.1-0.8-1.1-0.9-1.1-1.4-1.4-1.0-1.4
Short access day 1 total inactive lever presses0.50.71.90.80.31.40.40.30.60.60.61.31.2
Short access day 10 total inactive lever presses0.30.72.80.5-0.11.10.1-0.10.5-0.1-0.11.41.7
Short access day 1 total infusions0.40.51.30.50.61.20.60.80.80.30.30.90.8
Short access day 10 total infusions0.30.30.6-0.6-0.6-0.4-0.6-0.7-0.6-0.6-0.6-0.3-0.5
Short access total infusions0.60.81.0-1.0-0.9-0.5-1.0-0.8-0.8-1.0-1.0-0.6-0.9
Short access day 1 locomotion0.70.91.6-0.8-1.0-0.7-0.8-0.6-0.9-1.1-1.1-1.1-1.3
Short access day 10 total locomotion0.61.01.80.91.21.01.11.01.00.60.61.31.1
Short access total locomotion0.10.10.6-0.10.0-0.1-0.20.1-0.2-0.4-0.4-0.3-0.8
One hour access (0.3 mA shock)0.50.61.7-0.3-0.50.0-1.3-0.7-0.7-1.3-1.3-0.2-0.2
Compulsive drug intake1.01.23.41.31.91.30.20.60.60.10.11.31.5
One hour access (shock baseline)0.60.91.6-1.1-1.3-1.2-0.8-0.6-0.8-0.7-0.7-1.1-1.2
Social response proportion6.27.18.2-2.7-2.7-2.5-2.8-2.9-2.8-2.6-2.6-2.5-2.6
Social responses0.10.10.2-0.5-0.2-0.30.1-0.2-0.30.20.2-0.1-0.3
Social time1.31.72.3-1.3-1.5-1.5-1.1-1.4-1.4-1.0-1.0-1.5-1.4
Soleus weight0.10.20.60.40.30.5-0.10.00.3-0.1-0.10.80.7
Bone: stiffness0.10.20.50.40.00.20.60.50.40.70.70.20.2
Tibialis anterior weight0.31.01.4-1.1-0.9-0.8-1.0-1.1-1.0-1.2-1.2-0.6-0.6
Time to tail flick, vehicle, before self-admin1.71.83.1-1.1-1.7-1.0-1.8-1.3-1.2-1.5-1.5-0.9-1.0
Time to tail flick, vehicle, after self-admin0.70.92.30.81.50.40.80.91.00.90.91.01.0
Time to tail flick, test, before self-admin0.10.10.40.10.60.60.10.50.4-0.1-0.10.30.2
Time to tail flick, test, after self-admin1.92.05.01.21.21.00.71.21.60.90.92.22.2
Delta time to tail flick, vehicle, before/after SA4.03.95.31.82.31.62.01.92.02.12.11.92.0
Delta time to tail flick, test, before/after SA0.60.61.70.70.40.30.40.50.80.60.61.31.3
Tibia length1.64.35.6-2.3-2.2-2.0-2.0-2.2-2.2-1.5-1.5-2.3-2.4
Ambulatory time before self-admin0.20.30.8-0.9-0.2-0.8-0.3-0.3-0.6-0.2-0.2-0.6-0.8
Ambulatory time after self-admin0.20.30.60.1-0.0-0.70.2-0.0-0.20.80.8-0.4-0.7
Bone: tissue strength0.70.71.2-0.9-0.7-0.7-0.8-0.8-0.7-1.1-1.1-0.6-0.6
Total heroin consumption0.70.81.6-0.4-0.80.3-1.3-1.2-1.0-1.2-1.20.1-0.2
Bone: trabecular number0.10.20.40.60.60.10.40.50.40.40.40.20.1
Bone: trabecular spacing0.70.91.9-1.4-0.9-1.4-0.7-0.7-0.9-0.3-0.3-1.1-1.1
Bone: trabecular thickness0.10.10.30.50.50.30.20.20.3-0.0-0.00.30.2
Bone: trabecular tissue density0.40.51.1-0.7-0.4-1.0-0.3-0.4-0.6-0.7-0.7-1.1-1.0
Water consumed over 24 hours0.10.20.7-0.10.20.7-0.00.00.1-0.4-0.40.80.7
Number of responses in last shaping day1.61.72.60.91.21.41.41.51.40.90.91.61.6