Hub : Genes

Scp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr5_128093550_128094872 0.18 0.11 5.2e-12 0.12 0.13 0.15 0.12 5.1e-11 6.5e-12 8.4e-14 6.6e-11
2 NAcc gene expression Scp2 0.1 0.05 0.0e+00 0.13 0.13 0.13 0.13 1.5e-19 1.7e-19 1.3e-19 1.9e-19
3 OFC gene expression Scp2 0.24 0.14 2.8e-04 0.15 0.12 0.1 0.13 1.8e-04 8.7e-04 3.0e-03 6.4e-04
4 Brain gene expression Scp2 0.16 0.08 0.0e+00 0.21 0.24 0.24 0.24 5.5e-19 1.2e-22 3.3e-22 2.1e-22
5 PL mRNA stability Scp2 0.02 0.02 1.5e-03 0.02 0.02 0.01 0.02 1.6e-03 5.3e-03 1.1e-02 5.1e-03
6 IC gene expression Scp2 0.28 0.11 1.3e-14 0.31 0.31 0.3 0.32 1.0e-13 1.1e-13 3.4e-13 3.2e-14
7 Brain intron excision ratio chr5_128091657_128094872 0.17 0.1 5.8e-13 0.13 0.14 0.15 0.12 2.3e-12 9.9e-13 1.4e-13 1.2e-11
8 PL gene expression Scp2 0.2 0.09 0.0e+00 0.27 0.27 0.26 0.26 3.8e-29 3.2e-29 1.1e-28 1.8e-28
9 pVTA gene expression Scp2 0.26 0.12 0.0e+00 0.31 0.31 0.3 0.29 3.1e-25 4.2e-25 6.0e-25 7.5e-24
10 BLA intron excision ratio chr5_128091657_128094872 0.09 0.06 1.7e-03 0.02 0.04 0.03 0.03 2.1e-02 2.4e-03 7.0e-03 1.2e-02
11 Adipose intron excision ratio chr5_128091657_128094872 0.13 0.06 1.4e-15 0.1 0.11 0.12 0.11 1.8e-11 2.8e-12 3.3e-13 2.0e-12
12 pVTA mRNA stability Scp2 0.12 0.07 7.9e-14 0.18 0.16 0.16 0.18 4.2e-14 4.2e-13 3.4e-13 4.5e-14
13 RMTg gene expression Scp2 0.16 0.1 1.4e-03 0.03 0.05 0.04 0.03 7.1e-02 1.5e-02 3.4e-02 4.9e-02
14 PL intron excision ratio chr5_128091657_128094872 0.07 0.04 3.8e-09 0.07 0.07 0.07 0.08 2.2e-08 1.1e-07 1.6e-08 1.1e-08
15 NAcc intron excision ratio chr5_128091657_128094872 0.05 0.03 3.7e-12 0.07 0.07 0.06 0.07 5.6e-11 1.9e-11 4.0e-10 3.5e-11
16 Adipose mRNA stability Scp2 0.07 0.04 1.4e-06 0.05 0.04 0.04 0.05 7.2e-06 2.5e-05 8.5e-06 1.8e-06
17 Liver mRNA stability Scp2 0.17 0.08 0.0e+00 0.09 0.12 0.1 0.11 1.0e-09 8.9e-13 1.5e-11 7.4e-12
18 IC mRNA stability Scp2 0.42 0.17 3.3e-16 0.31 0.35 0.3 0.3 1.8e-13 2.6e-15 6.1e-13 2.8e-13
19 NAcc mRNA stability Scp2 0.06 0.03 3.3e-14 0.08 0.09 0.09 0.09 3.2e-12 4.1e-14 7.5e-14 2.6e-13
20 IL gene expression Scp2 0.29 0.14 5.4e-05 0.16 0.12 0.05 0.15 1.2e-04 9.0e-04 2.3e-02 2.1e-04
21 BLA gene expression Scp2 0.09 0.06 3.6e-04 -0 0.02 0.01 0 4.9e-01 3.8e-02 9.5e-02 2.8e-01
22 Liver gene expression Scp2 0.23 0.09 0.0e+00 0.2 0.21 0.2 0.21 1.5e-21 1.5e-22 5.8e-22 1.8e-22
23 Adipose gene expression Scp2 0.26 0.1 0.0e+00 0.13 0.17 0.19 0.18 3.8e-14 1.0e-18 1.8e-20 5.0e-20

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.71.34.9-1.9-1.0-0.91.0-0.71.32.21.1-1.0-0.7-0.2-1.11.2-1.2-1.20.80.90.91.2-0.51.1-1.1-1.0
Area under the delay curve0.10.10.50.2-0.2-0.10.1-0.2-0.1-0.4-0.0-0.10.2-0.10.1-0.10.20.1-0.7-0.4-0.4-0.3-0.0-0.50.50.5
BMI with tail1.03.67.31.12.52.7-2.42.0-1.9-2.1-2.32.41.4-0.82.0-2.42.12.2-1.1-1.2-1.2-1.91.9-1.41.41.7
BMI without tail0.31.83.1-1.11.61.6-1.61.3-1.3-0.0-1.61.51.5-1.81.4-1.31.81.4-0.8-1.1-1.3-1.21.4-0.91.01.1
Body weight0.62.65.2-0.32.12.3-2.01.8-2.0-0.7-1.92.01.5-1.51.7-1.91.91.8-1.0-1.2-1.2-1.51.8-1.11.11.4
Weight adjusted by age0.10.20.40.50.70.6-0.50.5-0.3-0.7-0.50.6-0.20.50.4-0.60.10.40.60.30.3-0.20.50.1-0.1-0.3
Bone surface0.30.64.1-2.0-0.7-0.60.6-0.10.71.70.6-0.7-0.2-0.5-0.60.7-0.6-0.70.30.30.30.6-0.10.5-0.5-0.4
Bone volume0.20.33.4-1.8-0.2-0.10.10.40.41.50.2-0.2-0.0-0.5-0.30.3-0.4-0.30.10.20.20.30.50.3-0.3-0.2
Breakpoint value in progressive ratio session0.10.11.01.0-0.1-0.30.2-0.10.4-0.30.2-0.1-0.40.5-0.20.1-0.7-0.20.40.30.40.2-0.40.2-0.3-0.4
Number of licking bursts0.10.20.60.10.50.6-0.4-0.00.30.1-0.30.5-0.60.8-0.1-0.4-0.20.20.80.60.60.10.60.4-0.4-0.5
Context. condit. distance diff. score0.91.14.3-1.8-0.5-0.60.8-0.61.02.10.9-0.7-0.80.3-1.11.0-1.0-1.01.11.01.01.1-0.31.2-1.2-1.1
Locomotion velocity, session 13.53.95.1-1.0-1.8-1.81.9-1.22.22.02.0-1.8-2.21.6-2.22.0-2.0-2.12.12.22.22.2-1.42.2-2.2-2.2
Locomotion distance, session 10.30.42.3-1.5-0.1-0.10.30.30.31.10.3-0.2-0.70.5-0.60.4-0.4-0.40.80.70.70.60.10.8-0.8-0.7
Locomotion velocity, session 23.64.45.9-1.8-1.7-1.82.0-1.22.42.42.0-1.7-2.31.9-2.32.0-2.0-2.22.32.32.32.3-1.22.4-2.3-2.4
Locomotion distance, session 20.81.11.6-1.20.80.8-1.01.1-1.0-0.0-1.00.81.2-1.21.1-0.91.21.0-1.1-1.2-1.2-1.11.2-1.11.11.1
Locomotion velocity, session 31.01.24.4-1.8-1.0-0.91.0-0.41.22.11.1-1.1-0.90.2-1.21.1-1.1-1.20.80.91.01.1-0.11.1-1.1-0.9
Locomotion distance, session 30.30.31.1-0.10.20.3-0.40.3-0.6-0.0-0.40.10.8-1.10.6-0.30.40.4-0.8-0.8-0.7-0.60.4-0.70.70.8
Stereotopy head waving bouts, day 30.20.20.7-0.3-0.10.20.10.30.40.30.20.0-0.80.8-0.30.1-0.4-0.30.60.70.80.50.40.7-0.7-0.5
Stereotopy head waving duration, day 31.01.22.4-1.5-0.4-0.30.60.11.11.40.7-0.4-1.41.2-1.10.6-0.8-0.91.51.51.41.20.31.5-1.4-1.3
Locomotion velocity, session 70.40.44.3-2.1-0.2-0.10.20.30.21.00.1-0.60.5-0.8-0.10.20.3-0.1-0.8-0.6-0.5-0.20.4-0.30.40.6
Locomotion distance, session 70.60.82.4-0.9-0.1-0.2-0.10.1-0.60.1-0.2-0.41.4-1.60.6-0.00.80.4-1.5-1.4-1.4-0.80.3-1.21.21.1
Stereotopy head waving bouts, day 71.92.23.2-0.7-1.4-1.21.5-1.11.71.41.6-1.4-1.81.5-1.71.4-1.7-1.61.41.71.71.7-0.91.7-1.7-1.5
Stereotopy head waving duration, day 72.12.63.8-0.8-1.4-1.41.6-1.11.81.51.6-1.5-1.91.6-1.91.5-1.8-1.71.61.81.91.8-0.81.8-1.8-1.7
Locomotion velocity, session 81.82.14.1-1.4-1.4-1.31.5-1.41.72.01.6-1.6-1.40.9-1.71.6-1.6-1.61.11.31.41.6-1.01.5-1.5-1.3
Locomotion distance, session 80.40.67.7-2.8-0.1-0.20.20.20.32.10.2-0.30.2-0.7-0.40.5-0.2-0.40.20.10.10.40.50.4-0.4-0.2
Degree of sensitization distance0.10.10.4-0.70.3-0.0-0.20.5-0.20.0-0.30.10.5-0.30.3-0.20.50.3-0.4-0.5-0.5-0.40.4-0.40.50.3
Degree of sensitization stereotypy1.11.21.7-0.9-1.0-1.01.2-0.91.31.21.2-1.1-1.20.9-1.31.1-1.2-1.20.91.11.11.1-0.71.1-1.1-1.0
Conditioned locomotion0.30.41.6-0.10.50.0-0.20.60.50.1-0.10.4-0.71.3-0.3-0.2-0.2-0.11.20.80.80.40.50.7-0.7-0.9
Cocaine response after cond. corrected2.03.04.60.31.41.5-1.71.2-2.0-1.3-1.81.52.1-2.22.0-1.61.81.8-1.9-2.0-2.0-1.91.1-1.91.91.9
Cocaine response after cond. not corrected2.23.25.70.11.61.7-1.91.4-2.0-1.0-1.91.82.2-2.42.0-1.71.91.9-1.8-1.9-2.0-1.91.3-1.81.81.9
Cocaine response before conditioning0.10.10.4-0.50.30.3-0.20.20.10.6-0.10.3-0.0-0.1-0.1-0.1-0.1-0.00.40.30.30.20.40.3-0.3-0.2
Saline control response0.50.82.50.8-0.00.1-0.1-0.4-0.6-0.8-0.3-0.11.3-1.40.7-0.10.60.4-1.6-1.3-1.3-0.8-0.5-1.11.11.2
Bone: connectivity density0.91.44.3-1.7-1.5-1.31.3-1.11.32.11.3-1.4-0.6-0.4-1.21.5-1.2-1.30.50.70.71.2-1.01.0-1.0-0.8
Bone: cortical apparent density1.93.05.1-0.2-1.6-1.81.8-1.72.31.61.8-1.6-1.71.3-1.91.8-1.7-1.81.71.71.71.9-1.71.8-1.8-1.9
Bone: cortical area1.32.13.4-1.51.51.4-1.51.8-1.6-0.0-1.51.41.7-1.61.5-1.31.51.4-1.3-1.4-1.4-1.41.5-1.31.31.4
Bone: cortical porosity1.01.13.10.2-0.0-0.00.3-0.11.00.60.50.1-1.51.6-1.00.3-1.0-0.71.81.61.61.1-0.11.5-1.5-1.4
Bone: cortical porosity1.31.53.80.4-0.4-0.30.7-0.41.20.50.9-0.3-1.72.0-1.20.6-1.3-1.01.71.81.81.3-0.51.6-1.6-1.5
Bone: cortical thickness2.23.67.1-1.42.42.3-2.22.7-2.1-0.6-2.22.21.7-1.22.0-2.12.02.1-1.3-1.5-1.5-1.92.5-1.51.51.7
Bone: cortical thickness1.11.43.2-0.01.81.8-1.61.7-1.2-0.6-1.51.70.8-0.31.2-1.50.91.3-0.4-0.5-0.5-1.01.6-0.60.60.8
Bone: cortical tissue density2.13.45.7-0.3-1.7-1.91.8-1.82.41.71.9-1.7-1.91.5-2.11.9-1.8-1.91.91.91.82.0-1.81.9-1.9-2.1
Condit. Reinf. active minus inactive responses0.40.41.10.00.80.6-0.80.6-0.7-0.1-0.80.90.8-1.00.8-0.70.60.7-0.2-0.5-0.6-0.60.4-0.50.50.4
Condit. Reinf. active-inactive response ratio0.60.61.4-0.70.90.9-0.90.8-1.00.2-0.90.91.0-1.20.9-0.70.70.8-0.5-0.7-0.7-0.70.7-0.60.60.7
Condit. Reinf. active responses0.81.11.71.01.21.1-1.31.0-1.0-1.3-1.21.30.9-0.61.2-1.31.01.2-0.5-0.8-0.8-1.10.7-0.90.90.7
Condit. Reinf. inactive responses0.30.43.11.70.30.3-0.40.1-0.3-1.8-0.40.30.10.50.4-0.50.50.5-0.4-0.4-0.4-0.6-0.1-0.60.60.4
Incentive salience index mean1.11.42.60.21.51.3-1.51.4-1.3-0.5-1.51.61.3-1.31.3-1.41.11.4-0.5-0.9-1.0-1.21.1-0.90.90.7
Condit. Reinf. lever presses1.11.62.8-0.41.71.5-1.61.6-1.4-0.4-1.61.71.3-1.31.3-1.51.31.5-0.5-1.0-1.1-1.21.2-0.90.90.8
Condit. Reinf. active minus inactive responses0.71.13.7-1.10.50.3-0.60.4-0.70.2-0.70.41.6-1.91.0-0.41.00.7-1.4-1.4-1.5-1.00.7-1.21.21.2
Condit. Reinf. active-inactive response ratio0.40.74.1-1.80.1-0.0-0.2-0.1-0.21.0-0.30.01.3-2.00.50.20.80.2-0.9-1.0-1.1-0.40.1-0.60.60.7
Condit. Reinf. active responses0.40.61.9-0.90.60.4-0.60.7-0.50.3-0.70.51.2-1.40.7-0.50.80.6-0.9-1.0-1.0-0.70.8-0.80.80.8
Condit. Reinf. inactive responses0.20.30.80.70.70.6-0.70.9-0.4-0.7-0.60.70.10.40.4-0.80.30.6-0.0-0.1-0.1-0.50.9-0.30.30.2
Condit. Reinf. lever presses0.20.41.60.8-0.7-0.80.3-0.40.0-0.30.2-0.60.8-1.30.20.30.2-0.0-0.8-0.8-0.8-0.3-0.5-0.70.70.4
Condit. Reinf. lever reinforcers received0.40.62.0-0.90.50.3-0.60.5-0.50.2-0.60.31.2-1.40.7-0.40.70.6-1.0-1.0-1.0-0.80.7-0.90.90.9
Conditioned reinforcement - actives0.93.75.81.01.81.3-1.81.2-1.9-1.5-2.01.72.4-1.62.3-1.71.92.0-2.3-2.4-2.4-2.21.0-2.32.32.2
Conditioned reinforcement - inactives0.00.10.30.50.40.1-0.20.1-0.2-0.3-0.20.30.10.40.4-0.3-0.10.2-0.1-0.1-0.1-0.20.3-0.20.20.1
Conditioned locomotion0.71.12.1-0.61.00.5-0.90.5-1.0-0.0-1.11.01.4-1.31.3-0.71.11.0-1.1-1.3-1.5-1.10.5-1.11.21.0
Patch foraging indifference point 0 sec0.20.71.3-0.50.80.7-0.90.7-0.8-0.2-0.90.81.1-1.10.9-0.71.00.8-0.7-0.9-1.0-0.80.4-0.80.80.7
Patch foraging indifference point AUC0.30.66.2-2.5-0.6-0.60.6-0.30.51.90.6-0.6-0.0-0.4-0.60.8-0.1-0.70.40.20.10.6-0.10.5-0.5-0.4
Delay disc. indifference point, 0s delay0.20.22.01.4-0.6-0.60.5-0.50.3-0.50.4-0.60.00.5-0.20.3-0.3-0.3-0.7-0.3-0.2-0.0-0.4-0.30.30.4
Delay disc. indifference point, 16s delay0.91.31.9-0.51.11.1-1.21.1-1.3-0.8-1.21.11.0-1.31.2-1.21.41.3-1.0-1.1-1.1-1.21.2-1.11.21.1
Delay disc. indifference point, 2s delay0.10.11.41.2-0.2-0.30.2-0.30.2-0.70.2-0.3-0.30.8-0.10.0-0.1-0.1-0.10.00.1-0.0-0.2-0.10.10.0
Delay disc. indifference point, 24s delay0.10.22.4-1.5-0.3-0.40.4-0.20.30.60.3-0.4-0.20.3-0.30.3-0.0-0.3-0.20.00.00.2-0.00.0-0.00.0
Delay disc. indifference point, 4s delay0.20.21.11.10.10.1-0.1-0.1-0.2-1.1-0.20.10.00.50.2-0.30.40.3-0.4-0.3-0.3-0.4-0.1-0.40.40.4
Delay disc. indifference point, 8s delay0.10.10.9-0.9-0.1-0.0-0.0-0.1-0.20.3-0.1-0.00.4-0.40.2-0.00.30.2-0.6-0.5-0.5-0.30.2-0.40.40.5
Indifference point function ln k0.20.61.81.30.90.9-0.90.8-0.7-1.2-0.80.80.6-0.50.8-0.90.60.8-0.6-0.6-0.6-0.70.4-0.60.60.6
Indifference point function log k0.20.61.81.30.90.9-0.90.8-0.7-1.2-0.80.80.6-0.50.8-0.90.60.8-0.6-0.6-0.6-0.70.4-0.60.60.6
Patch foraging total patch changes 0 sec0.20.51.3-0.70.80.6-0.80.7-0.7-0.0-0.80.71.0-1.10.8-0.60.90.7-0.5-0.7-0.9-0.70.3-0.60.60.5
Patch foraging total patch changes 12 sec0.81.12.4-0.3-1.2-1.51.2-1.11.11.11.2-1.2-0.70.6-1.21.3-0.9-1.20.90.80.71.1-1.20.9-0.9-1.2
Patch foraging total patch changes 18 sec0.10.20.5-0.00.50.6-0.60.4-0.5-0.0-0.60.60.7-0.70.6-0.50.40.6-0.3-0.5-0.5-0.50.3-0.40.40.5
Patch foraging total patch changes 24 sec0.31.11.7-0.51.21.1-1.31.1-1.1-0.7-1.31.20.8-0.51.2-1.31.21.2-0.5-0.8-0.8-1.11.1-0.90.90.8
Patch foraging total patch changes 6 sec0.40.72.6-1.00.30.4-0.50.6-0.80.3-0.50.31.2-1.60.7-0.31.00.5-1.1-1.1-1.1-0.70.2-0.80.81.0
Patch foraging time to switch 0 sec0.62.45.62.4-1.4-1.51.5-1.71.5-0.41.5-1.3-1.92.3-1.41.1-2.0-1.31.31.51.71.3-1.61.2-1.3-1.6
Patch foraging water rate 0 sec0.72.54.2-0.91.91.9-1.92.1-1.6-0.5-1.81.81.6-1.41.6-1.72.01.7-0.9-1.3-1.4-1.61.9-1.21.31.3
Patch foraging water rate 12 sec1.14.46.5-1.42.02.3-2.22.3-2.5-0.5-2.22.02.2-2.32.2-2.12.52.1-1.8-2.0-2.0-2.12.4-1.91.92.1
Patch foraging water rate 18 sec0.00.10.6-0.40.10.10.00.20.20.00.10.1-0.50.8-0.2-0.10.1-0.10.50.40.40.20.20.3-0.3-0.4
Patch foraging water rate 24 sec0.10.10.30.00.30.2-0.20.50.20.2-0.10.3-0.20.6-0.2-0.2-0.10.00.60.40.30.10.30.3-0.3-0.4
Patch foraging water rate 6 sec1.01.52.40.01.41.4-1.51.4-1.2-1.1-1.51.41.0-0.61.2-1.51.61.5-0.7-1.0-1.1-1.31.4-1.11.10.9
Seeking ratio, delayed vs. immediate footshock1.92.84.0-1.11.81.7-1.81.9-1.8-0.4-1.81.71.9-1.52.0-1.71.61.8-1.4-1.6-1.7-1.71.8-1.61.61.6
Distance traveled before self-admin0.30.88.9-3.00.50.5-0.41.2-0.31.7-0.40.50.3-0.70.3-0.20.30.20.30.1-0.00.01.40.2-0.2-0.1
Distance traveled after self-admin0.81.58.6-2.91.21.2-1.21.7-1.00.9-1.11.21.0-1.31.0-0.91.51.0-0.3-0.7-0.8-0.81.8-0.50.50.6
Extensor digitorum longus weight0.62.35.9-1.52.32.4-2.12.0-1.50.1-2.02.31.0-0.81.4-1.81.31.7-0.3-0.7-0.7-1.21.9-0.60.60.9
Bone: elastic displacement0.40.66.8-2.60.20.3-0.10.20.11.7-0.00.3-0.2-0.2-0.30.10.1-0.20.80.50.40.40.40.7-0.7-0.6
Bone: elastic work0.50.69.1-3.00.50.4-0.40.5-0.41.4-0.40.40.5-0.80.2-0.20.80.30.0-0.2-0.4-0.20.60.00.00.1
Bone: endosteal estimation0.10.21.2-0.6-0.6-0.20.4-0.60.20.80.4-0.30.3-1.1-0.20.6-0.3-0.4-0.1-0.1-0.10.3-0.90.2-0.20.0
Bone: endosteal perimeter0.10.31.20.4-0.9-0.60.6-0.70.1-0.00.5-0.70.4-1.1-0.10.6-0.3-0.4-0.6-0.4-0.40.1-1.0-0.30.30.3
Epididymis fat weight0.00.21.71.3-0.6-0.30.4-0.70.0-0.70.3-0.50.10.2-0.20.4-0.1-0.2-0.7-0.3-0.2-0.0-0.8-0.30.30.5
Delta time in closed arm before/after self-admin0.10.11.5-0.10.00.1-0.00.00.00.6-0.00.00.6-1.20.10.20.0-0.1-0.3-0.3-0.30.0-0.4-0.10.10.2
Delta time in open arm before/after self-admin0.10.10.50.30.20.0-0.3-0.0-0.3-0.7-0.40.40.10.50.4-0.30.60.4-0.3-0.4-0.5-0.4-0.1-0.40.40.2
Diff in mean of infusions in LGA sessions0.20.31.10.60.20.1-0.20.3-0.3-0.5-0.20.10.7-0.40.4-0.30.10.4-1.0-0.7-0.7-0.60.1-0.80.70.9
Delay discount exponential model param0.10.10.5-0.40.10.1-0.00.30.10.50.00.1-0.20.0-0.10.1-0.3-0.20.70.50.40.40.10.5-0.5-0.5
Extinction: sum of active levers before priming0.20.31.50.30.30.3-0.20.20.1-0.1-0.10.4-0.60.6-0.1-0.2-0.5-0.01.20.80.80.4-0.10.7-0.7-0.9
Active lever presses in extinction session 62.22.22.81.51.41.2-1.41.7-1.5-1.5-1.51.41.5-0.91.6-1.50.91.6-1.6-1.5-1.4-1.61.4-1.71.61.7
Bone: final force0.00.10.4-0.6-0.20.10.10.1-0.20.10.0-0.20.2-0.70.10.10.1-0.0-0.5-0.3-0.2-0.1-0.2-0.20.20.4
Bone: final moment0.10.20.8-0.7-0.00.2-0.10.2-0.50.1-0.10.00.5-0.90.3-0.10.30.2-0.7-0.5-0.5-0.3-0.1-0.40.40.6
Food consumed during 24 hour testing period0.81.63.40.30.30.3-0.70.4-1.3-1.3-0.90.31.7-1.71.2-0.71.31.0-1.8-1.8-1.8-1.40.2-1.81.81.6
Glucose0.30.51.1-0.90.30.7-0.40.6-0.7-0.1-0.50.30.7-0.50.7-0.50.60.6-1.0-0.8-0.7-0.70.7-0.80.81.1
Heart weight0.71.23.10.51.71.7-1.61.6-1.1-0.8-1.41.70.60.01.1-1.50.91.30.1-0.3-0.3-0.91.2-0.40.40.5
Delay discount hyperbolic model param0.10.10.3-0.60.20.2-0.10.30.00.6-0.00.2-0.0-0.2-0.10.1-0.2-0.10.60.30.30.30.20.4-0.4-0.4
Intermittent access intake day 1-15 change0.21.12.20.61.00.9-1.00.5-1.1-1.2-1.00.91.2-1.20.9-0.91.51.1-1.2-1.2-1.2-1.20.4-1.21.21.2
Intermittent access intake escalation0.20.92.10.41.01.0-1.00.6-1.0-1.2-1.00.91.0-0.90.9-1.01.51.0-0.9-1.0-1.0-1.00.5-1.01.01.0
Intermittent access intake escalation 20.20.30.90.50.60.5-0.50.1-0.5-0.9-0.50.40.5-0.30.4-0.50.90.5-0.5-0.5-0.6-0.5-0.1-0.50.50.5
Intermitt. access day 1 inactive lever presses0.11.82.7-0.71.51.2-1.51.4-1.4-0.3-1.51.41.6-1.11.7-1.31.31.5-1.1-1.4-1.4-1.41.3-1.31.31.3
Intermitt. access day 15 inactive lever presses0.10.41.0-0.21.00.7-0.80.7-0.5-0.3-0.81.00.40.10.8-0.80.50.70.1-0.3-0.3-0.50.6-0.30.30.2
Intermitt. access escalation Index0.00.10.4-0.5-0.10.30.00.10.00.10.2-0.1-0.4-0.1-0.30.00.1-0.20.60.50.50.3-0.00.5-0.5-0.4
Intermittent access day 1 total infusions0.10.42.3-0.1-0.0-0.40.3-0.10.50.30.3-0.1-0.81.5-0.30.2-0.8-0.40.90.70.80.5-0.20.6-0.7-0.9
Intermittent access day 15 total infusions0.10.20.70.30.80.5-0.60.4-0.5-0.8-0.60.70.10.50.5-0.60.50.60.1-0.1-0.2-0.40.2-0.20.20.0
Intermittent access terminal intake (last 3 days)0.00.00.2-0.10.40.1-0.20.1-0.2-0.3-0.20.2-0.00.50.2-0.20.20.20.20.10.0-0.1-0.10.0-0.0-0.2
Intermittent access total infusions0.10.21.30.20.2-0.10.1-0.20.2-0.20.10.1-0.51.1-0.10.0-0.3-0.10.70.50.50.3-0.40.4-0.4-0.6
Intermittent access day 1 locomotion0.10.21.20.50.0-0.30.1-0.40.3-0.00.20.0-0.51.1-0.10.1-0.7-0.20.60.50.50.3-0.30.4-0.4-0.6
Intermittent access day 15 total locomotion0.10.42.01.40.50.1-0.4-0.2-0.4-1.2-0.50.40.50.10.7-0.50.60.6-0.7-0.7-0.7-0.7-0.2-0.80.80.6
Intermittent access total locomotion0.10.10.60.40.2-0.0-0.0-0.30.1-0.3-0.00.2-0.40.8-0.0-0.0-0.2-0.00.60.40.30.2-0.50.3-0.3-0.5
Intermittent access standard deviation0.62.95.01.61.81.8-1.91.6-1.8-2.2-1.91.81.5-0.71.8-2.01.71.9-1.3-1.5-1.4-1.91.4-1.71.71.6
Left kidney weight2.621.229.3-0.65.45.4-5.45.3-5.3-2.8-5.35.24.5-3.55.0-5.25.25.1-3.3-4.0-4.1-4.85.1-4.04.14.2
Right kidney weight1.712.119.7-0.24.24.4-4.24.2-4.1-2.5-4.14.03.2-2.43.7-4.04.13.9-2.3-2.8-2.9-3.53.8-2.82.93.2
Cocaine induced anxiety0.10.41.0-1.00.90.8-0.80.3-0.7-0.5-0.80.8-0.00.10.7-0.80.70.60.90.20.0-0.30.40.1-0.1-0.5
Post-drug Anxiety0.60.61.8-1.31.11.0-1.00.8-0.9-0.4-0.91.0-0.10.20.9-1.00.60.71.30.40.3-0.30.90.2-0.2-0.8
Baseline Anxiety0.20.31.21.10.40.4-0.41.0-0.4-0.7-0.30.40.00.60.5-0.6-0.30.4-0.2-0.10.1-0.40.9-0.40.30.3
Tail length0.10.55.5-2.3-0.0-0.30.1-0.0-0.01.90.1-0.00.4-1.2-0.20.40.1-0.30.40.1-0.10.40.20.4-0.3-0.4
Length with tail0.21.03.2-1.80.90.9-0.90.8-1.20.7-0.90.91.3-1.71.0-0.61.20.8-0.7-0.9-1.1-0.80.9-0.70.70.8
Length without tail1.05.17.1-0.22.22.3-2.32.2-2.7-1.6-2.42.22.4-1.92.6-2.32.52.4-2.2-2.3-2.3-2.52.1-2.32.32.5
Times rat made contact with spout0.80.93.9-0.80.30.6-0.70.1-0.9-0.0-0.70.51.3-2.01.0-0.51.00.8-1.2-1.3-1.3-1.00.5-1.11.11.1
Lifetime Intake0.10.10.70.70.1-0.20.1-0.30.1-0.50.1-0.0-0.20.8-0.00.0-0.3-0.10.20.20.20.1-0.50.1-0.1-0.2
Liver weight, left0.00.10.3-0.1-0.5-0.30.4-0.1-0.0-0.10.3-0.5-0.10.4-0.10.2-0.1-0.2-0.4-0.2-0.10.00.1-0.20.20.3
Liver weight, right0.10.20.8-0.2-0.6-0.40.5-0.90.10.30.4-0.60.1-0.4-0.20.6-0.1-0.4-0.4-0.2-0.20.2-0.7-0.00.00.2
Locomotor activity0.50.71.91.3-0.0-0.1-0.30.1-0.6-1.1-0.40.01.1-0.80.7-0.30.80.6-1.4-1.2-1.2-0.9-0.2-1.21.21.0
Locomotor testing distance0.61.43.10.50.40.3-0.70.6-1.1-0.9-0.80.41.7-1.71.1-0.71.31.0-1.8-1.7-1.8-1.30.3-1.61.61.5
Locomotor testing rearing0.41.54.10.90.20.2-0.50.1-1.0-1.0-0.70.21.8-1.71.1-0.51.00.9-2.0-1.9-1.8-1.3-0.0-1.71.71.7
Locomotion in novel chamber3.75.06.71.91.92.1-2.22.3-2.3-2.4-2.32.02.2-1.32.3-2.42.02.4-2.5-2.3-2.2-2.52.3-2.52.52.6
Locomotion in novel chamber post-restriction0.10.31.3-0.80.50.4-0.40.7-0.30.6-0.30.6-0.40.50.2-0.3-0.20.11.10.60.60.20.90.6-0.6-0.8
Fecal boli incidents, locomotor time 10.10.31.20.70.10.1-0.20.1-0.3-0.5-0.20.10.8-0.60.3-0.10.40.3-1.1-0.8-0.8-0.5-0.2-0.80.70.9
Change in fecal boli incidents, locomotor task0.30.41.51.2-0.7-0.70.6-0.60.6-0.30.6-0.7-0.51.0-0.50.5-0.6-0.50.20.30.40.4-0.70.3-0.3-0.3
Time >=10cm from walls, locomotor time 11.51.93.3-1.4-1.0-0.91.2-0.71.41.81.3-0.9-1.30.4-1.51.4-1.4-1.51.81.61.51.7-0.91.8-1.8-1.7
Bouts of movement, locomotor time 10.40.51.20.2-1.1-0.91.0-0.90.60.40.9-0.9-0.5-0.2-0.70.9-0.8-0.80.00.30.40.6-1.10.3-0.4-0.3
Total resting periods, locomotor time 10.30.41.10.2-0.9-0.70.8-0.80.60.30.7-0.8-0.6-0.0-0.60.7-0.7-0.70.20.40.40.6-1.00.4-0.4-0.4
Rest time, locomotor task time 10.10.10.90.9-0.3-0.20.3-0.50.1-0.40.2-0.30.1-0.2-0.00.2-0.1-0.1-0.6-0.3-0.2-0.1-0.7-0.30.30.4
Distance moved, locomotor task time 10.30.93.2-1.8-0.2-0.40.40.10.61.50.5-0.3-0.91.2-0.60.5-0.6-0.71.41.11.00.90.51.1-1.1-1.3
Vertical activity count, locomotor time 10.00.30.8-0.70.60.4-0.60.8-0.5-0.1-0.60.50.30.30.6-0.60.70.6-0.1-0.3-0.4-0.50.9-0.30.30.2
Time >=10cm from walls, locomotor time 20.10.32.3-1.50.20.2-0.10.40.21.10.00.20.0-0.5-0.30.2-0.0-0.20.60.40.30.40.10.6-0.5-0.4
Bouts of movement, locomotor time 20.30.91.70.3-0.7-0.60.7-0.50.90.60.8-0.5-1.31.2-1.10.6-1.0-0.91.31.21.31.0-0.21.1-1.1-1.2
Total resting periods, locomotor time 20.20.81.40.5-0.7-0.60.7-0.50.80.40.8-0.5-1.21.1-1.00.6-1.0-0.81.21.11.20.9-0.31.0-1.0-1.1
Rest time, locomotor task time 20.20.32.41.6-0.4-0.30.4-0.60.1-1.10.3-0.3-0.30.6-0.10.1-0.2-0.1-0.5-0.1-0.1-0.1-0.7-0.30.30.3
Distance moved, locomotor task time 20.60.85.4-2.31.00.8-0.91.2-0.81.3-0.80.80.7-0.60.7-0.60.70.60.3-0.3-0.4-0.31.4-0.00.1-0.0
Vertical activity count, locomotor time 20.81.93.8-2.01.41.3-1.51.6-1.50.4-1.51.21.7-1.51.5-1.21.61.4-1.0-1.3-1.5-1.31.6-1.11.21.2
Light reinforcement 10.00.21.00.70.50.4-0.50.3-0.4-0.6-0.40.5-0.21.00.3-0.50.20.40.40.20.2-0.20.50.1-0.1-0.2
Light reinforcement 20.51.12.6-1.31.41.2-1.41.2-1.30.1-1.31.40.9-0.21.2-1.31.31.2-0.2-0.6-0.8-1.01.6-0.60.70.5
Bone: marrow area0.10.21.3-0.7-0.5-0.20.3-0.50.10.80.3-0.20.4-1.2-0.10.6-0.2-0.3-0.1-0.1-0.20.3-0.80.2-0.10.1
Bone: maximum diameter0.10.20.9-0.90.50.5-0.50.8-0.50.4-0.40.50.4-0.40.4-0.40.20.3-0.1-0.2-0.2-0.30.6-0.10.10.2
Bone: maximum force0.20.33.0-1.7-0.00.2-0.00.3-0.40.8-0.10.00.6-1.20.20.10.40.0-0.6-0.4-0.5-0.1-0.0-0.20.20.5
Bone: maximum moment0.20.43.6-1.90.10.3-0.20.4-0.60.8-0.30.20.8-1.40.4-0.00.50.2-0.7-0.6-0.7-0.30.1-0.30.40.6
Mean time between licks in bursts0.21.13.60.6-1.5-1.61.4-1.91.10.41.3-1.6-0.2-0.1-0.81.4-0.8-1.2-0.10.10.20.8-1.60.2-0.2-0.3
Mean num. licks in bursts0.41.24.6-0.40.30.4-0.60.5-1.3-0.4-0.70.41.6-2.11.1-0.51.10.8-1.6-1.5-1.6-1.10.1-1.31.31.4
Cd content in liver0.50.61.3-0.6-0.8-0.80.9-1.10.71.10.9-0.9-0.3-0.2-0.71.0-0.8-0.90.30.40.40.8-1.00.6-0.6-0.5
Co content in liver0.30.44.0-2.0-0.20.00.1-0.2-0.31.50.1-0.20.6-1.30.10.40.2-0.2-0.4-0.4-0.40.10.0-0.00.10.3
Cu content in liver0.60.73.3-0.3-0.7-0.60.4-0.2-0.2-0.20.2-0.71.1-1.80.40.40.6-0.0-1.4-1.2-1.2-0.5-0.7-1.01.01.0
Fe content in liver0.40.51.2-1.10.80.7-0.80.9-0.80.4-0.80.90.5-1.00.5-0.70.70.60.1-0.2-0.3-0.41.0-0.10.20.1
K content in liver0.50.41.30.5-0.7-0.80.4-0.2-0.3-0.50.2-0.70.8-0.90.30.30.3-0.0-1.2-1.0-1.0-0.5-0.1-1.01.00.7
Mg content in liver2.22.55.10.70.70.8-1.01.1-1.7-1.8-1.20.61.8-1.61.6-1.11.71.4-2.3-2.1-2.0-1.80.9-2.12.12.1
Mn content in liver0.30.30.60.4-0.5-0.70.6-0.10.50.20.6-0.5-0.70.8-0.60.5-0.6-0.60.60.60.60.6-0.40.5-0.6-0.7
Na content in liver0.20.20.9-0.2-0.8-1.00.7-0.20.40.50.7-0.8-0.1-0.3-0.50.7-0.3-0.60.10.10.10.4-0.40.2-0.2-0.3
Rb content in liver0.20.20.80.0-0.20.10.0-0.1-0.4-0.2-0.1-0.20.5-0.70.3-0.00.30.2-0.9-0.7-0.6-0.40.0-0.60.60.8
Se content in liver0.40.43.0-1.7-0.4-0.40.2-0.3-0.11.30.2-0.40.8-1.40.10.40.2-0.2-0.6-0.6-0.7-0.10.2-0.40.40.4
Sr content in liver0.00.00.20.2-0.0-0.10.00.00.10.50.10.00.1-0.3-0.10.1-0.2-0.10.20.10.10.20.00.2-0.2-0.2
Zn content in liver0.40.41.11.1-1.0-0.90.8-0.70.2-0.60.6-1.10.2-0.2-0.10.6-0.2-0.4-0.9-0.5-0.4-0.0-1.0-0.50.50.5
Bone: minimum diameter1.01.96.8-0.80.60.7-0.90.8-1.3-0.1-1.00.72.1-2.61.5-0.71.31.1-1.8-1.9-1.9-1.30.5-1.61.61.7
Time in familiar zone, hab. session 10.40.54.2-2.0-0.4-0.50.5-0.10.61.40.5-0.6-0.50.0-0.60.6-0.2-0.60.40.50.40.60.10.6-0.6-0.5
Time in novel zone, hab. session 10.20.21.61.3-0.5-0.40.3-0.70.2-0.30.3-0.30.3-0.6-0.10.4-0.5-0.2-0.2-0.2-0.20.1-0.8-0.10.10.1
Total zone transitions, hab. session 10.30.51.1-0.7-0.1-0.00.30.00.60.80.4-0.1-0.90.7-0.50.3-0.7-0.51.11.01.00.70.01.0-1.0-0.9
Total locomotion distance, hab. session 10.30.41.5-1.20.70.8-0.51.1-0.20.6-0.40.7-0.40.4-0.0-0.40.10.20.80.60.50.20.80.6-0.6-0.4
Locomotion velocity, hab. session 10.20.30.8-0.90.50.6-0.40.8-0.10.4-0.30.5-0.60.7-0.1-0.30.10.10.80.60.60.20.50.6-0.5-0.5
Time in familiar zone, hab. session 20.40.41.8-1.3-0.7-0.80.5-0.50.10.90.4-0.80.7-1.10.10.60.2-0.3-0.9-0.8-0.7-0.1-0.2-0.50.50.5
Time in novel zone, hab. session 20.10.10.90.90.20.3-0.20.0-0.0-0.4-0.10.3-0.40.2-0.2-0.1-0.30.00.60.50.50.2-0.20.5-0.5-0.4
Total zone transitions, hab. session 20.10.20.6-0.50.00.1-0.20.4-0.40.3-0.20.00.6-0.80.3-0.10.20.2-0.5-0.5-0.5-0.30.4-0.40.40.4
Total locomotion distance, hab. session 20.40.51.2-0.80.70.8-0.81.1-0.9-0.1-0.80.70.7-0.60.7-0.80.80.8-0.5-0.6-0.6-0.71.1-0.60.60.7
Locomotion velocity, hab. session 20.40.61.7-0.90.80.9-0.91.3-0.9-0.0-0.80.80.6-0.30.6-0.90.80.8-0.4-0.5-0.5-0.71.3-0.60.60.6
Novel to familiar place preference ratio1.72.25.11.40.90.9-1.20.9-1.6-2.3-1.31.01.5-0.91.7-1.31.61.5-1.8-1.8-1.7-1.70.6-1.81.81.7
Novelty place preference0.91.23.01.00.60.6-0.80.7-1.2-1.7-0.90.71.1-0.61.3-0.91.21.1-1.4-1.3-1.3-1.20.4-1.41.41.3
Time in novel zone, NPP test0.91.03.11.30.50.5-0.70.5-1.0-1.8-0.80.61.0-0.61.2-0.81.00.9-1.3-1.2-1.2-1.10.3-1.31.31.2
Total zone transitions, NPP test0.40.61.70.11.21.3-1.11.2-0.9-0.5-1.01.30.4-0.30.8-1.10.60.9-0.0-0.3-0.3-0.71.1-0.30.30.4
Total locomotion distance, NPP test0.60.92.6-0.31.31.3-1.31.6-1.0-0.4-1.21.30.6-0.30.9-1.20.81.1-0.2-0.4-0.5-0.81.4-0.50.50.5
Locomotion velocity, NPP test1.01.53.9-0.51.61.6-1.62.0-1.3-0.5-1.51.60.8-0.41.1-1.51.21.4-0.3-0.6-0.7-1.11.7-0.70.70.7
Intraocular pressure0.30.51.51.00.50.7-0.60.4-0.8-1.2-0.70.50.50.00.7-0.80.90.8-0.9-0.7-0.7-0.80.4-0.80.80.9
Delta distance traveled before/after self-admin1.41.52.50.91.21.3-1.30.7-1.3-1.4-1.31.21.2-1.21.3-1.31.61.3-1.1-1.2-1.3-1.30.8-1.21.31.3
Delta ambulatory time before/after self-admin0.71.22.61.21.01.1-1.10.6-1.1-1.6-1.11.00.9-0.81.1-1.21.31.2-1.0-1.0-1.1-1.20.5-1.11.11.1
Parametrial fat weight0.00.10.9-0.9-0.1-0.10.10.40.10.50.1-0.1-0.2-0.0-0.40.10.4-0.20.30.20.20.20.40.3-0.2-0.3
Pavlov. Cond. lever latency0.91.23.40.1-1.7-1.31.5-1.81.20.51.4-1.6-0.60.3-1.11.5-0.9-1.3-0.00.40.50.9-1.60.5-0.5-0.3
Pavlov. Cond. magazine entry latency0.30.41.71.3-0.6-0.80.6-0.60.5-0.30.6-0.6-0.40.2-0.60.5-0.7-0.50.40.40.40.5-1.00.3-0.3-0.5
Pavlov. Cond. change in total contacts0.00.10.20.10.2-0.1-0.10.50.20.1-0.00.2-0.20.3-0.1-0.0-0.2-0.00.50.30.30.10.10.2-0.2-0.4
Pavlov. Cond. index score0.10.20.60.50.70.4-0.60.8-0.5-0.4-0.60.60.2-0.10.4-0.60.20.50.2-0.1-0.1-0.40.5-0.20.2-0.1
Pavlov. Cond. latency score0.20.30.80.60.70.5-0.70.9-0.5-0.5-0.60.70.20.00.4-0.70.20.60.2-0.1-0.1-0.40.6-0.20.2-0.0
Pavlov. Cond. lever contacts0.70.82.6-0.01.41.0-1.31.6-0.9-0.5-1.21.30.4-0.10.8-1.20.71.00.2-0.3-0.3-0.81.4-0.40.40.2
Pavlov. Cond. magazine entry number0.40.52.4-1.60.60.8-0.60.4-0.50.3-0.60.60.6-0.50.6-0.51.00.6-0.6-0.6-0.6-0.60.8-0.50.50.7
Pavlov. Cond. intertrial magazine entries1.51.84.41.10.80.9-1.10.6-1.3-2.1-1.20.81.3-0.71.4-1.31.61.4-1.6-1.6-1.5-1.60.8-1.71.71.6
Pavlov. Cond. lever-magazine prob. diff.0.30.30.90.50.80.5-0.80.9-0.7-0.6-0.70.80.4-0.20.6-0.80.40.70.0-0.3-0.3-0.50.6-0.40.40.1
Pavlov. Cond. response bias0.00.10.30.40.3-0.1-0.20.4-0.1-0.0-0.20.3-0.0-0.0-0.0-0.2-0.20.10.50.20.20.10.10.2-0.2-0.4
Pavlov. Cond. lever latency0.81.22.9-1.50.30.30.2-0.10.61.50.40.2-1.41.4-0.90.4-0.8-0.61.71.61.51.10.01.6-1.6-1.3
Pavlov. Cond. magazine entry latency0.60.92.10.8-1.4-1.20.8-1.20.0-0.50.6-1.30.9-1.50.00.80.0-0.4-1.3-1.1-1.0-0.3-1.0-1.00.90.8
Pavlov. Cond. change in total contacts0.41.02.91.2-0.5-0.50.0-0.3-0.4-1.2-0.2-0.51.3-1.30.7-0.10.60.4-1.7-1.6-1.5-1.0-0.2-1.51.51.3
Pavlov. Cond. index score0.81.23.31.4-1.0-0.90.4-0.7-0.3-1.20.2-1.01.3-1.70.50.30.50.1-1.8-1.6-1.5-0.8-0.7-1.51.51.3
Pavlov. Cond. latency score0.71.13.21.2-1.0-0.90.3-0.6-0.3-1.10.1-0.91.3-1.70.50.20.50.2-1.8-1.6-1.5-0.8-0.5-1.51.51.2
Pavlov. Cond. lever contacts0.60.92.21.2-0.3-0.3-0.2-0.0-0.4-1.2-0.3-0.31.2-1.40.7-0.20.70.5-1.5-1.4-1.3-0.9-0.1-1.41.31.1
Pavlov. Cond. magazine entry number0.81.03.5-0.81.91.7-1.41.5-0.60.2-1.21.8-0.30.80.5-1.30.50.91.00.70.6-0.21.30.5-0.5-0.4
Pavlov. Cond. intertrial magazine entries0.40.84.00.50.1-0.10.2-0.40.90.00.40.1-1.42.0-0.80.1-0.8-0.41.51.31.30.8-0.11.1-1.1-1.2
Pavlov. Cond. lever-magazine prob. diff.0.91.43.71.4-1.1-1.00.4-0.8-0.4-1.20.2-1.01.4-1.80.50.30.50.1-1.9-1.7-1.6-0.8-0.8-1.61.61.3
Pavlov. Cond. response bias0.50.81.91.4-0.9-0.80.4-0.6-0.0-0.90.2-0.91.0-1.20.30.30.20.0-1.4-1.2-1.2-0.6-0.7-1.21.10.9
Time in closed arm before self-admin0.40.61.3-0.5-0.6-0.70.7-0.90.80.40.7-0.7-1.11.1-0.80.6-0.6-0.71.00.90.90.8-0.40.8-0.8-1.0
Time in closed arm after self-admin0.30.30.60.1-0.3-0.30.4-0.80.60.10.5-0.4-0.60.3-0.60.5-0.3-0.50.70.70.60.6-0.80.7-0.7-0.7
Time in open arm before self-admin0.30.42.00.60.00.2-0.20.7-0.4-0.2-0.20.00.9-1.40.4-0.20.20.3-1.2-0.8-0.7-0.50.3-0.70.71.0
Time in open arm after self-admin0.91.01.50.30.80.7-0.91.1-1.0-0.8-1.00.91.1-0.81.1-0.91.21.1-1.1-1.2-1.2-1.10.6-1.11.21.1
Bone: periosteal estimation0.30.82.4-1.50.70.9-0.81.0-0.90.6-0.80.81.1-1.60.9-0.50.80.7-0.7-0.8-0.9-0.70.6-0.60.60.8
Bone: periosteal perimeter0.20.31.6-0.50.20.3-0.30.6-0.60.1-0.40.30.8-1.30.6-0.20.40.4-0.8-0.7-0.7-0.50.2-0.60.60.7
Bone: post-yield work0.00.10.5-0.2-0.4-0.20.2-0.4-0.00.30.2-0.20.2-0.7-0.10.3-0.3-0.2-0.1-0.1-0.10.1-0.40.0-0.0-0.0
Progressive ratio test 1 active lever presses0.20.41.00.71.00.7-0.90.6-0.7-0.8-0.91.00.40.20.9-0.90.30.8-0.0-0.3-0.3-0.60.4-0.40.40.2
Progressive ratio test 1 breakpoint0.20.41.00.51.00.7-0.90.6-0.7-0.7-0.91.00.40.20.9-0.80.30.80.0-0.3-0.3-0.60.5-0.40.40.2
Progressive ratio test 1 inactive lever presses0.10.20.6-0.40.80.5-0.60.6-0.40.1-0.60.70.4-0.10.6-0.50.20.50.1-0.2-0.2-0.30.3-0.20.10.0
Progressive ratio test 2 active lever presses0.20.20.90.01.00.4-0.60.6-0.5-0.5-0.60.80.20.40.8-0.60.30.60.1-0.2-0.2-0.40.2-0.20.20.0
Progressive ratio test 2 breakpoint0.20.21.0-0.11.00.4-0.60.6-0.4-0.4-0.60.80.10.50.7-0.60.30.50.3-0.0-0.1-0.30.2-0.10.1-0.1
Progressive ratio test 2 inactive lever presses0.00.10.60.30.4-0.1-0.20.2-0.0-0.4-0.20.3-0.00.80.3-0.2-0.00.2-0.0-0.1-0.1-0.20.0-0.20.20.0
Incentive Sensitization - Responses0.00.10.40.60.2-0.10.0-0.00.0-0.60.00.1-0.20.60.1-0.10.10.00.10.10.1-0.0-0.30.0-0.0-0.1
Incentive Sensitization - Breakpoint0.00.10.40.50.30.0-0.00.0-0.0-0.6-0.00.1-0.20.50.2-0.10.20.10.10.10.0-0.1-0.3-0.00.0-0.0
Sum of active levers in priming session hrs 5-60.20.20.6-0.70.40.3-0.30.70.00.7-0.20.5-0.2-0.10.1-0.2-0.50.10.70.40.40.20.70.4-0.4-0.5
Progressive ratio0.20.51.30.10.60.6-0.71.0-0.8-0.9-0.70.60.30.30.6-0.90.60.8-0.6-0.6-0.5-0.81.1-0.80.80.7
Food seeking constrained by brief footshock2.73.45.0-0.7-1.9-2.12.1-2.11.81.92.0-2.0-1.51.0-2.02.2-1.9-2.11.51.61.52.0-2.21.8-1.8-1.8
Seeking ratio, punishment vs. effort1.94.16.5-0.7-2.1-2.12.2-2.32.12.52.2-2.1-1.40.2-2.12.5-2.0-2.41.71.71.62.3-2.62.1-2.1-1.9
Retroperitoneal fat weight0.10.31.10.9-0.6-0.40.6-0.80.4-0.60.6-0.5-0.81.0-0.50.4-0.3-0.50.20.50.50.4-1.00.4-0.4-0.3
Reaction time number correct0.10.30.7-0.80.20.30.1-0.10.50.70.20.1-0.50.4-0.40.2-0.2-0.30.80.80.70.6-0.20.8-0.8-0.5
Reaction time mean minus median0.21.39.53.1-0.6-0.60.2-0.6-0.3-2.00.0-0.50.9-0.50.6-0.00.10.3-1.7-1.4-1.2-0.8-0.7-1.41.41.2
Reaction time mean minus median AUC0.10.75.72.4-0.6-0.60.3-0.5-0.1-1.40.1-0.50.7-0.60.40.1-0.00.1-1.3-1.0-0.9-0.6-0.6-1.01.00.8
Reaction time num false alarms1.32.23.40.50.90.9-1.21.3-1.6-1.3-1.31.01.6-1.31.5-1.41.61.5-1.8-1.8-1.7-1.71.5-1.81.81.7
Reaction time num false alarms AUC1.63.65.30.71.31.3-1.71.7-2.1-1.6-1.81.42.2-1.82.0-1.82.01.9-2.2-2.3-2.2-2.21.9-2.32.32.2
Reaction time trials correct on left0.10.30.7-0.80.20.30.1-0.10.50.70.20.1-0.50.4-0.40.2-0.2-0.30.80.80.70.6-0.20.8-0.8-0.5
Reaction time trials on left0.10.20.5-0.70.20.30.1-0.20.50.60.10.1-0.50.4-0.30.2-0.2-0.30.70.70.60.5-0.20.7-0.7-0.4
Reaction time mean0.41.09.43.1-0.8-0.90.5-0.80.2-2.10.3-0.70.10.60.20.1-0.20.0-1.1-0.8-0.6-0.5-0.9-1.01.00.6
Reaction time mean AUC0.30.87.32.7-1.0-1.00.7-0.90.5-1.60.5-0.8-0.10.8-0.10.4-0.5-0.2-0.7-0.4-0.3-0.2-1.0-0.60.60.3
Median of all reaction times0.50.87.52.7-0.9-0.90.6-0.90.5-1.80.5-0.7-0.31.1-0.20.2-0.4-0.2-0.6-0.3-0.2-0.2-0.9-0.60.50.2
Reaction time omissions1.11.76.62.6-0.0-0.0-0.3-0.0-0.8-2.3-0.60.01.2-0.31.1-0.60.60.9-2.2-1.8-1.6-1.40.0-1.91.91.8
Reaction time false alarm rate2.94.06.41.01.21.2-1.71.7-2.3-1.8-1.81.32.3-2.02.1-1.82.02.0-2.4-2.5-2.4-2.31.9-2.52.52.3
Reaction time premature initiation rate0.10.20.80.2-0.5-0.90.4-0.80.0-0.20.2-0.40.40.0-0.00.40.2-0.2-0.3-0.5-0.6-0.1-0.9-0.40.4-0.1
Reaction time premature initiations0.10.21.1-0.3-0.5-0.80.5-1.00.40.30.4-0.4-0.10.4-0.30.6-0.0-0.40.20.1-0.10.3-1.00.2-0.2-0.4
Std. dev. reaction times0.41.47.92.8-0.4-0.50.0-0.4-0.5-2.1-0.2-0.31.1-0.60.8-0.20.40.5-1.9-1.6-1.4-1.1-0.6-1.71.61.4
Reaction time trials completed0.10.20.5-0.70.20.30.1-0.20.50.60.10.1-0.50.4-0.30.2-0.2-0.30.70.70.60.5-0.20.7-0.7-0.4
Reaction time trials AUC0.00.10.5-0.70.40.5-0.10.00.30.5-0.10.3-0.30.2-0.10.00.1-0.10.50.40.40.3-0.00.5-0.5-0.2
Run reversals in cocaine runway, females0.30.33.11.8-0.5-0.60.4-0.40.2-1.20.3-0.4-0.20.1-0.10.1-0.2-0.1-0.4-0.2-0.1-0.1-0.4-0.30.30.2
Run reversals in cocaine runway, males2.93.29.13.01.31.4-1.61.3-1.7-2.0-1.61.41.9-1.61.7-1.61.21.7-2.1-1.9-1.8-1.91.5-2.01.92.1
Latency to leave start box in cocaine runway0.30.41.20.21.01.1-1.00.8-0.6-0.4-0.91.00.3-0.60.7-0.90.40.80.3-0.1-0.1-0.50.9-0.20.10.1
Latency to leave start box in cocaine runway, F0.60.82.20.21.41.4-1.31.4-0.8-0.5-1.21.30.3-0.30.9-1.30.41.00.4-0.00.0-0.61.5-0.20.20.1
Latency to leave start box in cocaine runway, M0.10.10.50.5-0.3-0.20.2-0.60.1-0.10.1-0.20.3-0.4-0.10.20.1-0.1-0.7-0.4-0.4-0.1-0.6-0.30.30.5
Std. dev. time between licks in bursts1.12.13.71.5-1.8-1.81.8-1.91.70.11.7-1.9-1.31.5-1.61.6-1.6-1.60.61.01.11.3-1.70.9-1.0-1.0
Total sessions with >9 infusions0.20.33.41.9-0.1-0.30.2-0.50.1-0.80.1-0.10.00.50.00.1-0.5-0.0-0.3-0.2-0.1-0.1-0.7-0.30.20.2
Short access day 1 total inactive lever presses0.81.52.70.31.61.5-1.51.6-1.4-1.4-1.41.50.9-0.11.5-1.61.11.4-0.6-0.8-0.8-1.31.4-1.01.00.9
Short access day 10 total inactive lever presses0.10.76.1-2.50.60.6-0.61.0-0.50.9-0.60.50.7-1.00.4-0.41.10.5-0.5-0.6-0.6-0.51.0-0.40.50.6
Short access day 1 total infusions0.10.11.41.20.20.0-0.00.10.1-0.80.00.1-0.20.90.0-0.2-0.50.00.20.20.30.0-0.20.0-0.1-0.1
Short access day 10 total infusions0.10.21.1-0.20.50.2-0.30.20.0-0.1-0.20.4-0.51.00.1-0.2-0.20.10.90.50.50.2-0.00.4-0.4-0.7
Short access total infusions0.10.21.51.2-0.1-0.30.2-0.40.3-0.60.2-0.2-0.30.9-0.20.1-0.6-0.20.10.20.30.2-0.60.1-0.1-0.2
Short access day 1 locomotion0.81.31.81.11.10.8-1.00.7-1.1-1.4-1.11.11.3-0.61.3-1.01.01.2-1.2-1.3-1.3-1.30.3-1.31.31.2
Short access day 10 total locomotion0.10.50.90.30.80.8-0.90.7-0.8-0.8-0.90.90.5-0.30.7-0.90.90.9-0.3-0.5-0.6-0.80.7-0.60.60.5
Short access total locomotion0.10.10.20.3-0.2-0.30.3-0.50.30.10.2-0.2-0.30.3-0.30.3-0.4-0.30.30.30.30.3-0.50.3-0.3-0.4
One hour access (0.3 mA shock)0.10.10.60.2-0.3-0.60.4-0.60.30.10.3-0.3-0.20.4-0.00.4-0.2-0.30.00.10.00.2-0.80.1-0.1-0.2
Compulsive drug intake0.60.91.3-0.7-1.0-0.70.9-1.10.81.11.0-0.9-1.00.3-0.81.0-0.9-1.11.01.11.01.1-0.91.1-1.1-1.0
One hour access (shock baseline)0.41.11.60.61.30.9-1.21.0-1.0-1.2-1.21.21.0-0.21.2-1.21.11.2-0.9-1.1-1.1-1.20.8-1.21.21.0
Social response proportion0.20.21.41.2-0.5-0.80.5-0.70.4-0.60.4-0.5-0.10.6-0.20.4-0.5-0.3-0.1-0.1-0.10.1-0.8-0.10.1-0.2
Social responses0.91.22.51.0-1.4-1.61.4-1.51.30.21.3-1.4-0.80.9-1.11.3-1.2-1.20.40.60.60.9-1.40.6-0.6-0.7
Social time0.20.30.60.50.20.2-0.30.1-0.5-0.6-0.40.20.70.10.5-0.40.40.4-0.7-0.7-0.7-0.60.5-0.70.70.6
Soleus weight2.36.711.3-0.93.23.4-3.13.2-2.6-1.4-3.03.12.3-2.02.7-3.02.72.9-1.9-2.1-2.1-2.62.9-2.12.12.4
Bone: stiffness0.00.00.10.1-0.1-0.00.10.00.0-0.10.1-0.10.2-0.30.10.1-0.2-0.0-0.4-0.2-0.1-0.0-0.2-0.10.10.2
Tibialis anterior weight2.06.715.7-2.04.04.0-3.53.6-2.6-0.2-3.33.91.6-1.02.5-3.32.42.9-0.4-1.0-1.1-2.23.8-1.11.11.5
Time to tail flick, vehicle, before self-admin1.11.43.01.21.51.7-1.51.6-1.4-1.4-1.41.50.7-0.81.3-1.60.91.3-0.1-0.5-0.5-1.01.4-0.70.60.6
Time to tail flick, vehicle, after self-admin0.30.63.01.20.81.1-0.90.7-0.8-1.7-0.70.9-0.30.80.6-1.10.50.80.30.20.3-0.50.9-0.20.10.0
Time to tail flick, test, before self-admin1.21.34.0-1.01.82.0-1.71.2-1.3-1.1-1.51.8-0.10.21.0-1.61.41.21.20.40.2-0.61.00.2-0.1-0.4
Time to tail flick, test, after self-admin0.70.81.8-1.01.31.3-1.21.3-0.9-0.7-1.01.10.20.30.9-1.21.00.90.2-0.1-0.1-0.71.3-0.30.30.2
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.30.10.2-0.20.3-0.1-0.3-0.10.1-0.20.50.1-0.30.20.10.20.20.2-0.10.60.0-0.0-0.1
Delta time to tail flick, test, before/after SA0.10.21.10.6-0.3-0.50.30.10.1-0.10.2-0.40.4-0.10.00.2-0.2-0.1-1.0-0.6-0.4-0.30.3-0.60.60.7
Tibia length0.20.51.71.30.70.4-0.80.5-0.7-1.2-0.70.70.7-0.40.7-0.80.80.8-0.4-0.6-0.6-0.70.3-0.70.70.4
Ambulatory time before self-admin0.20.78.3-2.90.30.3-0.31.0-0.21.9-0.20.30.4-0.90.20.00.2-0.00.10.0-0.10.11.20.2-0.2-0.0
Ambulatory time after self-admin0.40.72.7-1.60.91.0-0.91.1-0.80.4-0.90.90.7-1.10.8-0.71.10.7-0.2-0.5-0.6-0.61.1-0.30.40.4
Bone: tissue strength0.40.51.2-0.9-1.1-1.10.8-0.90.30.80.8-1.00.1-0.7-0.50.9-0.1-0.7-0.2-0.1-0.20.4-0.90.1-0.0-0.1
Total heroin consumption0.60.75.52.3-0.6-0.70.6-0.60.8-1.00.6-0.5-0.80.9-0.60.4-1.3-0.50.30.60.70.5-0.90.4-0.4-0.5
Bone: trabecular number0.61.13.1-1.4-1.1-1.11.1-1.11.41.81.1-1.2-0.6-0.3-1.11.3-1.0-1.20.50.70.61.1-1.00.9-0.9-0.8
Bone: trabecular spacing0.91.43.01.31.51.6-1.41.7-1.2-1.7-1.31.40.30.61.0-1.60.81.3-0.4-0.4-0.3-1.11.6-0.70.70.8
Bone: trabecular thickness0.40.51.7-1.2-1.0-1.20.8-0.60.81.30.8-0.9-0.0-0.5-0.50.9-0.5-0.7-0.10.10.00.5-0.60.2-0.2-0.4
Bone: trabecular tissue density0.30.61.4-0.9-0.4-0.60.60.10.80.90.6-0.4-1.01.2-0.80.5-0.5-0.71.01.00.90.80.20.9-0.9-1.0
Water consumed over 24 hours0.81.66.6-1.00.80.9-1.10.7-1.20.2-1.10.91.9-2.61.2-0.81.21.1-1.4-1.5-1.6-1.20.6-1.21.31.3
Number of responses in last shaping day2.02.63.90.41.71.7-1.81.7-1.7-1.4-1.81.71.7-1.12.0-1.71.71.8-1.4-1.6-1.5-1.71.6-1.61.61.6