Hub : Genes

Scp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr5_128093550_128094872 0.18 0.11 5.2e-12 0.12 0.13 0.15 0.12 5.1e-11 6.5e-12 9.2e-14 6.6e-11
2 NAcc gene expression Scp2 0.1 0.05 0.0e+00 0.13 0.13 0.13 0.13 1.5e-19 1.7e-19 1.3e-19 2.1e-19
3 OFC gene expression Scp2 0.24 0.14 2.8e-04 0.15 0.12 0.1 0.13 1.8e-04 8.7e-04 3.0e-03 6.4e-04
4 Brain gene expression Scp2 0.16 0.08 0.0e+00 0.21 0.24 0.24 0.24 5.5e-19 1.2e-22 3.3e-22 2.3e-22
5 PL mRNA stability Scp2 0.02 0.02 1.5e-03 0.02 0.02 0.01 0.02 1.6e-03 5.3e-03 1.1e-02 5.1e-03
6 IC gene expression Scp2 0.28 0.11 1.3e-14 0.31 0.31 0.3 0.32 1.0e-13 1.1e-13 3.4e-13 3.1e-14
7 Brain intron excision ratio chr5_128091657_128094872 0.17 0.1 5.8e-13 0.13 0.14 0.15 0.12 2.3e-12 9.9e-13 1.3e-13 1.3e-11
8 PL gene expression Scp2 0.2 0.09 0.0e+00 0.27 0.27 0.26 0.26 3.8e-29 3.2e-29 1.1e-28 1.8e-28
9 pVTA gene expression Scp2 0.26 0.12 0.0e+00 0.31 0.31 0.3 0.29 3.1e-25 4.2e-25 5.9e-25 6.8e-24
10 BLA intron excision ratio chr5_128091657_128094872 0.09 0.06 1.7e-03 0.02 0.04 0.03 0.03 2.1e-02 2.4e-03 7.0e-03 1.1e-02
11 Adipose intron excision ratio chr5_128091657_128094872 0.13 0.06 1.4e-15 0.1 0.11 0.12 0.11 1.8e-11 2.8e-12 3.0e-13 1.9e-12
12 pVTA mRNA stability Scp2 0.12 0.07 7.9e-14 0.18 0.16 0.16 0.18 4.2e-14 4.2e-13 3.4e-13 4.3e-14
13 RMTg gene expression Scp2 0.16 0.1 1.4e-03 0.03 0.05 0.04 0.03 7.1e-02 1.5e-02 3.4e-02 5.3e-02
14 PL intron excision ratio chr5_128091657_128094872 0.07 0.04 3.8e-09 0.07 0.07 0.07 0.08 2.2e-08 1.1e-07 1.7e-08 9.7e-09
15 NAcc intron excision ratio chr5_128091657_128094872 0.05 0.03 3.7e-12 0.07 0.07 0.06 0.07 5.6e-11 1.9e-11 4.3e-10 3.6e-11
16 Adipose mRNA stability Scp2 0.07 0.04 1.4e-06 0.05 0.04 0.04 0.05 7.2e-06 2.5e-05 8.0e-06 1.7e-06
17 Liver mRNA stability Scp2 0.17 0.08 0.0e+00 0.09 0.12 0.1 0.11 1.0e-09 8.9e-13 1.6e-11 7.1e-12
18 IC mRNA stability Scp2 0.42 0.17 3.3e-16 0.31 0.35 0.3 0.3 1.8e-13 2.6e-15 6.2e-13 2.7e-13
19 NAcc mRNA stability Scp2 0.06 0.03 3.3e-14 0.08 0.09 0.09 0.09 3.2e-12 4.1e-14 8.0e-14 2.4e-13
20 IL gene expression Scp2 0.29 0.14 5.4e-05 0.16 0.12 0.05 0.15 1.2e-04 9.0e-04 2.3e-02 2.0e-04
21 BLA gene expression Scp2 0.09 0.06 3.6e-04 -0 0.02 0.01 0 4.9e-01 3.8e-02 9.4e-02 2.6e-01
22 Liver gene expression Scp2 0.23 0.09 0.0e+00 0.2 0.21 0.2 0.21 1.5e-21 1.5e-22 5.8e-22 1.8e-22
23 Adipose gene expression Scp2 0.26 0.1 0.0e+00 0.13 0.17 0.19 0.18 3.8e-14 1.0e-18 1.8e-20 5.4e-20

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.71.34.91.91.00.91.00.71.3-2.21.11.0-0.70.21.11.2-1.2-1.20.80.90.91.20.51.1-1.11.0
Area under the delay curve0.10.10.5-0.20.20.10.10.2-0.10.4-0.00.10.20.1-0.1-0.10.20.1-0.7-0.4-0.4-0.30.0-0.50.5-0.5
BMI with tail1.03.67.3-1.1-2.5-2.7-2.4-2.0-1.92.1-2.3-2.41.40.8-2.0-2.42.12.2-1.1-1.2-1.2-1.9-1.9-1.41.4-1.7
BMI without tail0.61.83.11.1-1.6-1.6-1.6-1.3-1.30.0-1.6-1.51.51.8-1.4-1.31.81.4-0.8-1.1-1.3-1.2-1.4-0.91.0-1.1
Body weight0.62.65.20.3-2.1-2.3-2.0-1.8-2.00.7-1.9-2.01.51.5-1.7-1.91.91.8-0.9-1.2-1.2-1.5-1.8-1.11.1-1.4
Weight adjusted by age0.10.20.4-0.5-0.7-0.6-0.5-0.5-0.30.7-0.5-0.6-0.2-0.5-0.4-0.60.10.40.60.30.3-0.2-0.50.1-0.10.3
Bone surface0.30.64.12.00.70.60.60.10.7-1.70.60.7-0.20.50.60.7-0.6-0.70.20.30.30.60.10.5-0.50.4
Bone volume0.20.33.41.80.20.10.1-0.40.4-1.50.20.2-0.00.50.30.3-0.4-0.30.10.20.20.3-0.50.3-0.30.2
Breakpoint value in progressive ratio session0.10.11.0-1.00.10.30.20.10.40.30.20.1-0.4-0.50.20.1-0.7-0.20.40.30.40.20.40.2-0.30.4
Number of licking bursts0.10.20.6-0.1-0.5-0.6-0.40.00.3-0.1-0.3-0.5-0.6-0.80.1-0.4-0.20.20.80.60.60.1-0.60.4-0.40.5
Context. condit. distance diff. score0.91.14.31.80.50.60.80.61.0-2.10.90.7-0.8-0.31.11.0-1.0-1.01.11.01.01.10.31.2-1.21.1
Locomotion velocity, session 13.63.95.11.01.81.81.91.22.2-2.02.01.8-2.2-1.62.22.0-2.0-2.12.12.22.22.21.42.2-2.22.2
Locomotion distance, session 10.30.42.31.50.10.10.3-0.30.3-1.10.30.2-0.7-0.50.60.4-0.4-0.40.80.70.70.6-0.10.8-0.80.7
Locomotion velocity, session 23.74.45.91.81.71.82.01.22.4-2.42.01.7-2.3-1.92.32.0-2.0-2.22.32.32.32.31.22.4-2.32.4
Locomotion distance, session 20.81.11.61.2-0.8-0.8-1.0-1.1-1.00.0-1.0-0.81.21.2-1.1-0.91.21.0-1.1-1.2-1.2-1.1-1.2-1.11.1-1.1
Locomotion velocity, session 31.11.24.41.81.00.91.00.41.2-2.11.11.1-0.9-0.21.21.1-1.1-1.20.80.91.01.10.11.1-1.10.9
Locomotion distance, session 30.30.31.10.1-0.2-0.3-0.4-0.3-0.60.0-0.4-0.10.81.1-0.6-0.30.40.4-0.8-0.8-0.7-0.6-0.4-0.70.7-0.8
Stereotopy head waving bouts, day 30.20.20.70.30.1-0.20.1-0.30.4-0.30.2-0.0-0.8-0.80.30.1-0.4-0.30.60.70.80.5-0.40.7-0.70.5
Stereotopy head waving duration, day 31.01.22.41.50.40.30.6-0.11.1-1.40.70.4-1.4-1.21.10.6-0.8-0.91.51.51.41.2-0.31.5-1.41.3
Locomotion velocity, session 70.40.44.32.10.20.10.2-0.30.2-1.00.10.60.50.80.10.20.3-0.1-0.8-0.6-0.5-0.2-0.4-0.30.4-0.6
Locomotion distance, session 70.60.82.50.90.10.2-0.1-0.1-0.6-0.1-0.20.41.41.6-0.6-0.00.80.4-1.5-1.4-1.4-0.8-0.3-1.21.2-1.1
Stereotopy head waving bouts, day 72.02.23.20.71.41.21.51.11.7-1.41.61.4-1.8-1.51.71.4-1.7-1.61.41.71.71.70.91.7-1.71.5
Stereotopy head waving duration, day 72.12.63.80.81.41.41.61.11.8-1.51.61.5-1.9-1.61.91.5-1.8-1.71.61.81.91.80.81.8-1.81.7
Locomotion velocity, session 81.82.14.11.41.41.31.51.41.7-2.01.61.6-1.4-0.91.71.6-1.6-1.61.11.31.41.61.01.5-1.51.3
Locomotion distance, session 80.40.67.72.80.10.20.2-0.20.3-2.10.20.30.20.70.40.5-0.2-0.40.20.10.10.4-0.50.4-0.40.2
Degree of sensitization distance0.10.10.40.7-0.30.0-0.2-0.5-0.2-0.0-0.3-0.10.50.3-0.3-0.20.50.3-0.4-0.5-0.5-0.4-0.4-0.40.5-0.3
Degree of sensitization stereotypy1.11.21.70.91.01.01.20.91.3-1.21.21.1-1.2-0.91.31.1-1.2-1.20.91.11.11.10.71.1-1.11.0
Conditioned locomotion0.30.41.60.1-0.5-0.0-0.2-0.60.5-0.1-0.1-0.4-0.7-1.30.3-0.2-0.2-0.11.20.80.80.4-0.50.7-0.70.9
Cocaine response after cond. corrected2.53.04.6-0.3-1.4-1.5-1.7-1.2-2.01.3-1.8-1.52.12.2-2.0-1.61.81.8-1.9-2.0-2.0-1.9-1.1-1.91.9-1.9
Cocaine response after cond. not corrected2.83.25.7-0.1-1.6-1.7-1.9-1.4-2.01.0-1.9-1.82.22.4-2.0-1.71.91.9-1.8-1.9-2.0-1.9-1.3-1.81.8-1.9
Cocaine response before conditioning0.10.10.40.5-0.3-0.3-0.2-0.20.1-0.6-0.1-0.3-0.00.10.1-0.1-0.1-0.00.40.30.30.2-0.40.3-0.30.2
Saline control response0.60.82.6-0.80.0-0.1-0.10.4-0.60.8-0.30.11.31.4-0.7-0.10.60.4-1.6-1.3-1.3-0.80.5-1.11.1-1.2
Bone: connectivity density0.91.44.31.71.51.31.31.11.3-2.11.31.4-0.60.41.21.5-1.2-1.30.50.70.71.21.01.0-1.00.8
Bone: cortical apparent density2.23.05.10.21.61.81.81.72.3-1.61.81.6-1.7-1.31.91.8-1.7-1.81.71.71.71.91.71.8-1.81.9
Bone: cortical area1.42.13.41.5-1.5-1.4-1.5-1.8-1.60.0-1.5-1.41.71.6-1.5-1.31.51.4-1.3-1.4-1.4-1.4-1.5-1.31.3-1.4
Bone: cortical porosity1.01.13.1-0.20.00.00.30.11.0-0.60.5-0.1-1.5-1.61.00.3-1.0-0.71.81.61.61.10.11.5-1.51.4
Bone: cortical porosity1.41.53.8-0.40.40.30.70.41.2-0.50.90.3-1.7-2.01.20.6-1.3-1.01.71.81.81.30.51.6-1.61.5
Bone: cortical thickness2.23.67.11.4-2.4-2.3-2.2-2.7-2.10.6-2.2-2.21.71.2-2.0-2.12.02.1-1.3-1.5-1.5-1.9-2.5-1.51.5-1.7
Bone: cortical thickness1.21.43.20.0-1.8-1.8-1.6-1.7-1.20.6-1.5-1.70.80.3-1.2-1.50.91.3-0.4-0.5-0.5-1.0-1.6-0.60.6-0.8
Bone: cortical tissue density2.53.45.70.31.71.91.81.82.4-1.71.91.7-1.9-1.52.11.9-1.8-1.91.91.91.82.01.81.9-1.92.1
Condit. Reinf. active minus inactive responses0.40.41.1-0.0-0.8-0.6-0.8-0.6-0.70.1-0.8-0.90.81.0-0.8-0.70.60.7-0.2-0.5-0.6-0.6-0.4-0.50.5-0.4
Condit. Reinf. active-inactive response ratio0.60.61.40.7-0.9-0.9-0.9-0.8-1.0-0.2-0.9-0.91.01.2-0.9-0.70.70.8-0.5-0.7-0.7-0.7-0.7-0.60.6-0.7
Condit. Reinf. active responses0.81.11.7-1.0-1.2-1.1-1.3-1.0-1.01.3-1.2-1.30.90.6-1.2-1.31.01.2-0.5-0.8-0.8-1.1-0.7-0.90.9-0.7
Condit. Reinf. inactive responses0.30.43.1-1.7-0.3-0.3-0.4-0.1-0.31.8-0.4-0.30.1-0.5-0.4-0.50.50.5-0.4-0.4-0.4-0.60.1-0.60.6-0.4
Incentive salience index mean1.11.42.6-0.2-1.5-1.3-1.5-1.4-1.30.5-1.5-1.61.31.2-1.3-1.41.11.4-0.5-0.9-1.0-1.2-1.1-0.90.9-0.7
Condit. Reinf. lever presses1.11.62.80.4-1.7-1.5-1.6-1.6-1.40.4-1.6-1.71.31.3-1.3-1.51.31.5-0.5-1.0-1.1-1.2-1.2-0.90.9-0.8
Condit. Reinf. active minus inactive responses0.81.13.71.1-0.5-0.3-0.6-0.4-0.7-0.2-0.7-0.41.61.9-1.0-0.41.00.7-1.4-1.4-1.5-1.0-0.7-1.21.2-1.2
Condit. Reinf. active-inactive response ratio0.60.74.11.8-0.10.0-0.20.1-0.2-1.0-0.3-0.01.32.0-0.50.20.80.2-0.9-1.0-1.1-0.4-0.1-0.60.6-0.7
Condit. Reinf. active responses0.40.61.90.9-0.6-0.4-0.6-0.7-0.5-0.3-0.7-0.51.21.4-0.7-0.50.80.6-0.9-1.0-1.0-0.7-0.8-0.80.8-0.8
Condit. Reinf. inactive responses0.20.30.8-0.7-0.7-0.6-0.7-0.9-0.40.7-0.6-0.70.1-0.4-0.4-0.80.30.6-0.0-0.1-0.1-0.5-0.9-0.30.3-0.2
Condit. Reinf. lever presses0.30.41.6-0.80.70.80.30.40.00.30.20.60.81.3-0.20.30.2-0.0-0.8-0.8-0.8-0.30.5-0.70.7-0.4
Condit. Reinf. lever reinforcers received0.40.62.00.9-0.5-0.3-0.6-0.5-0.5-0.2-0.6-0.31.21.4-0.7-0.40.70.6-1.0-1.0-1.0-0.8-0.7-0.90.9-0.9
Conditioned reinforcement - actives2.23.75.8-1.0-1.8-1.3-1.8-1.2-1.91.5-2.0-1.72.41.6-2.3-1.71.92.0-2.3-2.4-2.4-2.2-1.0-2.32.3-2.2
Conditioned reinforcement - inactives0.00.10.3-0.5-0.4-0.1-0.2-0.1-0.20.3-0.2-0.30.1-0.4-0.4-0.3-0.10.2-0.1-0.1-0.1-0.2-0.3-0.20.2-0.1
Conditioned locomotion0.81.12.10.6-1.0-0.5-0.9-0.5-1.00.0-1.1-1.01.41.3-1.3-0.71.11.0-1.1-1.3-1.5-1.1-0.5-1.11.2-1.0
Patch foraging indifference point 0 sec0.40.71.30.5-0.8-0.7-0.9-0.7-0.80.2-0.9-0.81.11.1-0.9-0.71.00.8-0.7-0.9-1.0-0.8-0.4-0.80.8-0.7
Patch foraging indifference point AUC0.40.66.22.50.60.60.60.30.5-1.90.60.6-0.00.40.60.8-0.1-0.70.40.20.10.60.10.5-0.50.4
Delay disc. indifference point, 0s delay0.20.22.0-1.40.60.60.50.50.30.50.40.60.0-0.50.20.3-0.3-0.3-0.7-0.3-0.2-0.00.4-0.30.3-0.4
Delay disc. indifference point, 16s delay1.11.31.90.5-1.1-1.1-1.2-1.1-1.30.8-1.2-1.11.01.3-1.2-1.21.41.3-1.0-1.1-1.1-1.2-1.2-1.11.2-1.1
Delay disc. indifference point, 2s delay0.10.11.4-1.20.20.30.20.30.20.70.20.3-0.3-0.80.10.0-0.1-0.1-0.20.00.1-0.00.2-0.10.1-0.0
Delay disc. indifference point, 24s delay0.20.22.41.50.30.40.40.20.3-0.60.30.4-0.2-0.30.30.3-0.0-0.3-0.20.00.00.20.00.0-0.0-0.0
Delay disc. indifference point, 4s delay0.20.21.1-1.1-0.1-0.1-0.10.1-0.21.1-0.2-0.10.0-0.5-0.2-0.30.40.3-0.4-0.3-0.3-0.40.1-0.40.4-0.4
Delay disc. indifference point, 8s delay0.10.10.90.90.10.0-0.00.1-0.2-0.3-0.10.00.40.4-0.2-0.00.30.2-0.6-0.5-0.5-0.3-0.2-0.40.4-0.5
Indifference point function ln k0.30.61.8-1.3-0.8-0.9-0.9-0.8-0.71.2-0.8-0.80.60.5-0.8-0.90.60.8-0.6-0.6-0.6-0.7-0.4-0.60.6-0.6
Indifference point function log k0.30.61.8-1.3-0.8-0.9-0.9-0.8-0.71.2-0.8-0.80.60.5-0.8-0.90.60.8-0.6-0.6-0.6-0.7-0.4-0.60.6-0.6
Patch foraging total patch changes 0 sec0.30.51.30.7-0.8-0.6-0.8-0.7-0.70.0-0.8-0.71.01.1-0.8-0.60.90.7-0.5-0.7-0.9-0.7-0.3-0.60.6-0.5
Patch foraging total patch changes 12 sec0.81.12.40.31.21.51.21.11.1-1.11.21.2-0.7-0.61.21.3-0.9-1.20.90.80.71.11.20.9-0.91.2
Patch foraging total patch changes 18 sec0.20.20.50.0-0.5-0.6-0.6-0.4-0.50.0-0.6-0.60.70.7-0.6-0.50.40.6-0.3-0.5-0.5-0.5-0.3-0.40.4-0.5
Patch foraging total patch changes 24 sec0.61.11.70.5-1.2-1.1-1.3-1.1-1.20.7-1.3-1.20.80.5-1.2-1.31.21.2-0.5-0.8-0.8-1.1-1.1-0.90.9-0.8
Patch foraging total patch changes 6 sec0.40.72.61.0-0.3-0.4-0.5-0.6-0.8-0.3-0.5-0.31.21.6-0.7-0.31.00.5-1.1-1.1-1.1-0.7-0.2-0.80.8-1.0
Patch foraging time to switch 0 sec1.22.45.6-2.41.41.51.51.71.50.41.51.3-1.9-2.31.41.1-2.0-1.31.31.51.71.31.61.2-1.31.6
Patch foraging water rate 0 sec1.22.54.20.9-1.9-1.9-1.9-2.1-1.60.5-1.8-1.81.61.4-1.6-1.72.01.7-0.9-1.3-1.4-1.6-1.9-1.21.3-1.3
Patch foraging water rate 12 sec2.14.46.51.4-2.0-2.3-2.2-2.3-2.50.5-2.2-2.02.22.3-2.2-2.12.52.1-1.8-2.0-2.0-2.1-2.4-1.91.9-2.1
Patch foraging water rate 18 sec0.10.10.60.4-0.1-0.10.0-0.20.2-0.00.1-0.1-0.5-0.80.2-0.10.1-0.10.50.40.40.2-0.20.3-0.30.4
Patch foraging water rate 24 sec0.10.10.3-0.0-0.3-0.2-0.2-0.50.2-0.2-0.1-0.3-0.2-0.60.2-0.2-0.10.00.60.40.30.1-0.30.3-0.30.4
Patch foraging water rate 6 sec1.01.52.4-0.0-1.4-1.4-1.5-1.4-1.21.1-1.5-1.41.00.6-1.2-1.51.61.5-0.7-1.0-1.1-1.3-1.4-1.11.1-0.9
Seeking ratio, delayed vs. immediate footshock2.32.84.01.1-1.8-1.7-1.8-1.9-1.80.4-1.8-1.71.91.5-2.0-1.71.61.8-1.4-1.6-1.7-1.7-1.8-1.61.6-1.6
Distance traveled before self-admin0.60.88.93.0-0.5-0.5-0.4-1.2-0.3-1.7-0.4-0.50.30.7-0.3-0.20.30.20.30.1-0.00.0-1.40.2-0.20.1
Distance traveled after self-admin1.21.58.62.9-1.2-1.2-1.2-1.7-1.0-0.9-1.1-1.21.01.3-1.0-0.91.51.0-0.3-0.7-0.8-0.8-1.8-0.50.5-0.6
Extensor digitorum longus weight0.62.35.91.5-2.3-2.4-2.1-2.0-1.5-0.1-2.0-2.31.00.8-1.4-1.81.31.7-0.3-0.7-0.7-1.2-1.9-0.60.6-0.9
Bone: elastic displacement0.50.66.82.6-0.2-0.3-0.1-0.20.1-1.7-0.0-0.3-0.20.20.30.10.1-0.20.80.50.40.4-0.40.7-0.70.6
Bone: elastic work0.50.69.13.0-0.5-0.4-0.4-0.5-0.4-1.4-0.4-0.40.50.8-0.2-0.20.80.30.0-0.2-0.4-0.2-0.60.00.0-0.1
Bone: endosteal estimation0.10.21.20.60.60.20.40.60.2-0.80.40.30.31.10.20.6-0.3-0.4-0.1-0.1-0.10.30.90.2-0.2-0.0
Bone: endosteal perimeter0.10.31.2-0.40.90.60.60.70.10.00.50.70.41.10.10.6-0.3-0.4-0.6-0.4-0.40.11.0-0.30.3-0.3
Epididymis fat weight0.10.21.7-1.30.60.30.40.70.00.70.30.50.1-0.20.20.4-0.1-0.2-0.7-0.3-0.2-0.00.8-0.30.3-0.5
Delta time in closed arm before/after self-admin0.10.11.50.1-0.0-0.1-0.0-0.00.0-0.6-0.0-0.00.61.2-0.10.20.0-0.1-0.3-0.3-0.30.00.4-0.10.1-0.2
Delta time in open arm before/after self-admin0.10.10.5-0.3-0.2-0.0-0.30.0-0.30.7-0.4-0.40.1-0.5-0.4-0.30.60.4-0.3-0.4-0.5-0.40.1-0.40.4-0.2
Diff in mean of infusions in LGA sessions0.20.31.1-0.6-0.2-0.1-0.2-0.3-0.30.5-0.2-0.10.70.4-0.4-0.30.10.4-1.0-0.7-0.7-0.6-0.1-0.80.7-0.9
Delay discount exponential model param0.10.10.50.4-0.1-0.1-0.0-0.30.1-0.50.0-0.1-0.2-0.00.10.1-0.3-0.20.70.50.40.4-0.10.5-0.50.5
Extinction: sum of active levers before priming0.30.31.5-0.3-0.3-0.3-0.2-0.20.10.1-0.1-0.4-0.6-0.60.1-0.2-0.5-0.01.20.80.80.40.10.7-0.70.9
Active lever presses in extinction session 62.22.22.8-1.5-1.4-1.2-1.4-1.7-1.51.5-1.5-1.41.50.9-1.6-1.50.91.6-1.6-1.5-1.4-1.6-1.4-1.71.6-1.7
Bone: final force0.00.10.40.60.2-0.10.1-0.1-0.2-0.10.00.20.20.7-0.10.10.1-0.0-0.5-0.3-0.2-0.10.2-0.20.2-0.4
Bone: final moment0.10.20.80.70.0-0.2-0.1-0.2-0.5-0.1-0.1-0.00.50.9-0.3-0.10.30.2-0.7-0.5-0.5-0.30.1-0.40.4-0.6
Food consumed during 24 hour testing period1.21.63.4-0.3-0.3-0.3-0.7-0.4-1.31.3-0.9-0.31.71.7-1.2-0.71.31.0-1.8-1.8-1.8-1.4-0.2-1.81.8-1.6
Glucose0.30.51.10.9-0.3-0.7-0.4-0.6-0.70.1-0.5-0.30.70.5-0.7-0.50.60.6-1.0-0.8-0.7-0.7-0.7-0.80.8-1.1
Heart weight0.81.23.1-0.5-1.7-1.7-1.6-1.6-1.10.8-1.4-1.70.6-0.0-1.1-1.50.91.30.1-0.3-0.3-0.9-1.2-0.40.4-0.5
Delay discount hyperbolic model param0.10.10.30.6-0.2-0.2-0.1-0.30.0-0.6-0.0-0.2-0.00.20.10.1-0.2-0.10.60.30.30.3-0.20.4-0.40.4
Intermittent access intake day 1-15 change0.61.12.2-0.6-1.0-0.9-1.0-0.5-1.11.2-1.0-0.91.21.2-0.9-0.91.51.1-1.2-1.2-1.2-1.2-0.4-1.21.2-1.2
Intermittent access intake escalation0.40.92.1-0.4-1.0-1.0-1.0-0.6-1.01.2-1.0-0.91.00.9-0.9-1.01.41.0-0.9-1.0-1.0-1.0-0.5-1.01.0-1.0
Intermittent access intake escalation 20.20.30.9-0.5-0.6-0.5-0.5-0.1-0.50.9-0.5-0.40.50.3-0.4-0.50.90.5-0.5-0.5-0.6-0.50.1-0.50.5-0.5
Intermitt. access day 1 inactive lever presses0.51.82.70.7-1.5-1.2-1.5-1.4-1.40.3-1.5-1.41.61.1-1.7-1.31.31.5-1.1-1.4-1.4-1.4-1.3-1.31.3-1.3
Intermitt. access day 15 inactive lever presses0.20.41.00.2-1.0-0.7-0.8-0.7-0.50.3-0.8-1.00.4-0.1-0.8-0.80.50.70.1-0.3-0.3-0.5-0.6-0.30.3-0.2
Intermitt. access escalation Index0.10.10.40.50.1-0.30.0-0.10.0-0.10.20.1-0.40.10.30.00.1-0.20.60.50.50.30.00.5-0.50.4
Intermittent access day 1 total infusions0.20.42.30.10.00.40.30.10.5-0.30.30.1-0.8-1.50.30.2-0.8-0.40.90.70.80.50.20.6-0.70.9
Intermittent access day 15 total infusions0.10.20.7-0.3-0.8-0.5-0.6-0.4-0.50.8-0.6-0.70.1-0.5-0.5-0.60.50.60.1-0.1-0.2-0.4-0.2-0.20.2-0.0
Intermittent access terminal intake (last 3 days)0.00.00.20.1-0.4-0.1-0.2-0.1-0.20.3-0.2-0.2-0.0-0.5-0.2-0.20.20.20.20.10.0-0.10.10.0-0.00.2
Intermittent access total infusions0.10.21.3-0.2-0.20.10.10.20.20.20.1-0.1-0.5-1.10.10.0-0.3-0.10.70.50.50.30.40.4-0.40.6
Intermittent access day 1 locomotion0.10.21.2-0.5-0.00.30.10.40.30.00.2-0.0-0.5-1.10.10.1-0.7-0.20.60.50.50.30.30.4-0.40.6
Intermittent access day 15 total locomotion0.20.42.0-1.4-0.5-0.1-0.40.2-0.41.2-0.5-0.40.5-0.1-0.7-0.50.50.6-0.7-0.7-0.7-0.70.2-0.80.8-0.6
Intermittent access total locomotion0.10.10.6-0.4-0.20.0-0.00.30.10.3-0.0-0.2-0.4-0.80.0-0.0-0.2-0.00.60.40.30.20.50.3-0.30.5
Intermittent access standard deviation1.42.95.0-1.6-1.8-1.8-1.9-1.6-1.82.2-1.9-1.81.50.7-1.8-2.01.71.9-1.3-1.5-1.4-1.9-1.4-1.71.7-1.6
Left kidney weight4.621.229.30.6-5.4-5.4-5.4-5.3-5.32.8-5.3-5.24.53.5-5.0-5.25.25.1-3.3-4.0-4.1-4.8-5.1-4.04.1-4.2
Right kidney weight2.712.119.70.2-4.2-4.4-4.2-4.2-4.12.5-4.1-4.03.22.3-3.7-4.04.13.9-2.3-2.8-2.9-3.5-3.8-2.82.9-3.2
Cocaine induced anxiety0.30.41.01.0-0.9-0.8-0.8-0.3-0.70.5-0.8-0.8-0.0-0.1-0.7-0.80.70.60.90.20.0-0.3-0.40.1-0.10.5
Post-drug Anxiety0.60.61.81.3-1.1-1.0-1.0-0.8-0.90.4-0.9-1.0-0.1-0.2-0.9-1.00.60.71.30.40.3-0.3-0.90.2-0.20.8
Baseline Anxiety0.20.31.2-1.1-0.4-0.4-0.4-1.0-0.40.7-0.3-0.40.0-0.6-0.5-0.6-0.30.4-0.2-0.10.1-0.4-0.9-0.40.3-0.3
Tail length0.10.55.52.30.00.30.10.0-0.0-1.90.10.00.41.10.20.40.1-0.30.40.1-0.10.4-0.20.4-0.30.4
Length with tail0.21.03.21.8-0.9-0.9-0.9-0.8-1.2-0.7-0.9-0.91.31.7-1.0-0.61.20.8-0.7-0.9-1.1-0.8-0.9-0.70.7-0.8
Length without tail1.65.17.10.2-2.2-2.3-2.3-2.2-2.71.6-2.4-2.22.41.9-2.6-2.32.52.4-2.2-2.3-2.3-2.5-2.1-2.32.3-2.5
Times rat made contact with spout0.80.93.90.8-0.3-0.6-0.7-0.1-0.90.0-0.7-0.51.32.0-1.0-0.51.00.8-1.2-1.3-1.3-1.0-0.5-1.11.1-1.1
Lifetime Intake0.10.10.7-0.7-0.10.20.10.30.10.50.10.0-0.2-0.80.00.0-0.3-0.10.20.20.20.10.50.1-0.10.2
Liver weight, left0.00.10.30.10.50.30.40.1-0.00.10.30.5-0.1-0.40.10.2-0.1-0.2-0.4-0.2-0.10.0-0.1-0.20.2-0.3
Liver weight, right0.10.20.80.20.60.40.50.90.1-0.30.40.60.10.40.20.6-0.1-0.4-0.4-0.2-0.20.20.7-0.00.0-0.2
Locomotor activity0.50.71.9-1.30.00.1-0.3-0.1-0.61.1-0.4-0.01.10.8-0.7-0.30.80.6-1.4-1.2-1.2-0.90.2-1.21.2-1.0
Locomotor testing distance0.81.43.2-0.5-0.4-0.3-0.7-0.6-1.10.9-0.8-0.41.71.7-1.1-0.71.31.0-1.8-1.7-1.8-1.3-0.3-1.61.6-1.5
Locomotor testing rearing0.71.54.1-0.9-0.2-0.2-0.5-0.1-1.01.0-0.7-0.21.81.7-1.1-0.51.00.9-2.0-1.9-1.8-1.30.0-1.71.7-1.7
Locomotion in novel chamber3.95.06.7-1.9-1.9-2.1-2.2-2.3-2.32.4-2.3-2.02.21.3-2.3-2.42.02.4-2.5-2.3-2.2-2.5-2.3-2.52.5-2.6
Locomotion in novel chamber post-restriction0.20.31.30.8-0.5-0.4-0.4-0.7-0.3-0.6-0.3-0.6-0.4-0.5-0.2-0.3-0.20.11.10.60.60.2-0.90.6-0.60.8
Fecal boli incidents, locomotor time 10.20.31.2-0.7-0.1-0.1-0.2-0.1-0.30.5-0.2-0.10.80.6-0.3-0.10.40.3-1.1-0.8-0.8-0.50.2-0.80.7-0.9
Change in fecal boli incidents, locomotor task0.40.41.5-1.20.70.70.60.60.60.30.60.7-0.5-1.00.50.5-0.6-0.50.20.30.40.40.70.3-0.30.3
Time >=10cm from walls, locomotor time 11.81.93.31.41.00.91.20.71.4-1.81.30.9-1.3-0.41.51.4-1.4-1.51.81.61.51.70.91.8-1.81.7
Bouts of movement, locomotor time 10.40.51.2-0.21.10.91.00.90.6-0.40.90.9-0.50.20.70.9-0.8-0.80.00.30.40.61.10.3-0.40.3
Total resting periods, locomotor time 10.30.41.1-0.20.90.70.80.80.6-0.30.70.8-0.60.00.60.7-0.7-0.70.20.40.40.61.00.4-0.40.4
Rest time, locomotor task time 10.10.10.9-0.90.30.20.30.50.10.40.20.30.10.20.00.2-0.1-0.1-0.6-0.3-0.2-0.10.7-0.30.3-0.4
Distance moved, locomotor task time 10.60.93.21.80.20.40.4-0.10.6-1.50.50.3-0.9-1.20.60.5-0.6-0.71.41.11.00.9-0.51.1-1.11.3
Vertical activity count, locomotor time 10.10.30.80.7-0.6-0.4-0.6-0.8-0.50.1-0.6-0.50.3-0.3-0.6-0.60.70.6-0.1-0.3-0.4-0.5-0.9-0.30.3-0.2
Time >=10cm from walls, locomotor time 20.20.32.31.5-0.2-0.2-0.1-0.40.2-1.10.0-0.20.00.50.30.2-0.0-0.20.60.40.30.4-0.10.6-0.50.4
Bouts of movement, locomotor time 20.50.91.7-0.30.70.60.70.50.9-0.60.80.5-1.3-1.21.10.6-1.0-0.91.31.21.31.00.21.1-1.11.2
Total resting periods, locomotor time 20.40.81.4-0.50.70.60.70.50.8-0.40.80.5-1.2-1.11.00.6-1.0-0.81.21.11.20.90.31.0-1.01.1
Rest time, locomotor task time 20.20.32.4-1.60.40.30.40.60.11.10.30.3-0.3-0.60.10.1-0.2-0.1-0.5-0.1-0.1-0.10.7-0.30.3-0.3
Distance moved, locomotor task time 20.60.85.42.3-1.0-0.8-0.9-1.2-0.8-1.3-0.8-0.80.70.6-0.7-0.60.70.60.3-0.3-0.4-0.3-1.4-0.00.10.0
Vertical activity count, locomotor time 21.41.93.82.0-1.4-1.3-1.5-1.6-1.5-0.4-1.5-1.21.71.5-1.5-1.21.61.4-1.0-1.3-1.5-1.3-1.6-1.11.2-1.2
Light reinforcement 10.10.21.0-0.7-0.5-0.4-0.5-0.3-0.40.6-0.4-0.5-0.2-1.0-0.3-0.50.20.40.40.20.2-0.2-0.50.1-0.10.2
Light reinforcement 20.71.12.61.3-1.4-1.2-1.4-1.2-1.3-0.1-1.3-1.40.90.2-1.2-1.31.31.2-0.2-0.6-0.8-1.0-1.6-0.60.7-0.5
Bone: marrow area0.10.21.30.70.50.20.30.50.1-0.80.30.20.41.20.10.6-0.2-0.3-0.1-0.1-0.20.30.80.2-0.1-0.1
Bone: maximum diameter0.10.20.90.9-0.5-0.5-0.5-0.8-0.5-0.4-0.4-0.50.40.4-0.4-0.40.20.3-0.1-0.2-0.2-0.3-0.6-0.10.1-0.2
Bone: maximum force0.20.33.01.70.0-0.2-0.0-0.3-0.4-0.8-0.1-0.00.61.2-0.20.10.40.0-0.6-0.4-0.5-0.10.0-0.20.2-0.5
Bone: maximum moment0.30.43.61.9-0.1-0.3-0.2-0.4-0.6-0.8-0.3-0.20.81.4-0.4-0.00.50.2-0.7-0.6-0.7-0.3-0.1-0.30.4-0.6
Mean time between licks in bursts0.41.13.6-0.61.51.61.41.91.1-0.41.31.6-0.20.10.81.4-0.8-1.2-0.10.10.20.81.60.2-0.20.3
Mean num. licks in bursts0.81.24.60.4-0.3-0.4-0.6-0.5-1.30.4-0.7-0.41.62.1-1.1-0.51.10.8-1.6-1.5-1.6-1.1-0.1-1.31.3-1.4
Cd content in liver0.50.61.30.60.80.80.91.10.7-1.10.90.9-0.30.20.71.0-0.8-0.90.30.40.40.81.00.6-0.60.5
Co content in liver0.40.44.02.00.2-0.00.10.2-0.3-1.50.10.20.61.3-0.10.40.2-0.2-0.4-0.4-0.40.1-0.0-0.00.1-0.3
Cu content in liver0.60.73.30.30.70.60.40.2-0.20.20.20.71.11.8-0.40.40.6-0.0-1.4-1.2-1.2-0.50.7-1.01.0-1.0
Fe content in liver0.40.51.21.1-0.8-0.7-0.8-0.9-0.8-0.4-0.8-0.90.51.0-0.5-0.70.70.60.1-0.2-0.3-0.4-1.0-0.10.2-0.1
K content in liver0.50.41.4-0.50.70.80.40.2-0.30.50.20.70.80.9-0.30.30.3-0.0-1.2-1.0-1.0-0.50.1-1.01.0-0.7
Mg content in liver2.42.55.1-0.7-0.7-0.8-1.0-1.1-1.71.8-1.2-0.61.81.6-1.6-1.11.71.4-2.3-2.1-2.0-1.8-0.9-2.12.1-2.1
Mn content in liver0.30.30.6-0.40.50.70.60.10.5-0.20.60.5-0.7-0.80.60.5-0.6-0.60.60.60.60.60.40.5-0.60.7
Na content in liver0.20.20.90.20.81.00.70.20.4-0.50.70.8-0.10.30.50.7-0.3-0.60.10.10.10.40.40.2-0.20.3
Rb content in liver0.20.20.9-0.00.2-0.10.00.1-0.40.2-0.10.20.50.7-0.3-0.00.30.2-0.9-0.7-0.6-0.4-0.0-0.60.6-0.8
Se content in liver0.40.43.01.70.40.40.20.3-0.1-1.30.20.40.81.4-0.10.40.2-0.2-0.6-0.6-0.7-0.1-0.2-0.40.4-0.4
Sr content in liver0.00.00.2-0.20.00.10.0-0.00.1-0.50.1-0.00.10.30.10.1-0.2-0.10.20.10.10.2-0.00.2-0.20.2
Zn content in liver0.40.41.1-1.11.00.90.80.70.20.60.61.10.20.20.10.6-0.2-0.4-0.9-0.5-0.4-0.01.0-0.50.5-0.5
Bone: minimum diameter1.01.96.80.8-0.6-0.7-0.9-0.8-1.30.1-1.0-0.72.12.6-1.5-0.71.31.1-1.9-1.9-1.9-1.3-0.5-1.61.6-1.7
Time in familiar zone, hab. session 10.50.54.22.00.40.50.50.10.6-1.40.50.6-0.5-0.00.60.6-0.2-0.60.40.50.40.6-0.10.6-0.60.5
Time in novel zone, hab. session 10.20.21.6-1.30.50.40.30.70.20.30.30.30.30.60.10.4-0.5-0.2-0.2-0.2-0.20.10.8-0.10.1-0.1
Total zone transitions, hab. session 10.30.51.10.70.10.00.3-0.00.6-0.80.40.1-0.9-0.70.50.3-0.7-0.51.11.01.00.7-0.01.0-1.00.9
Total locomotion distance, hab. session 10.30.41.51.2-0.7-0.8-0.5-1.1-0.2-0.6-0.4-0.7-0.4-0.40.0-0.40.10.20.80.60.50.2-0.80.6-0.60.4
Locomotion velocity, hab. session 10.20.30.80.9-0.5-0.6-0.4-0.8-0.1-0.4-0.3-0.5-0.6-0.70.1-0.30.10.10.80.60.60.2-0.50.6-0.50.5
Time in familiar zone, hab. session 20.40.41.81.30.70.80.50.50.1-0.90.40.80.71.1-0.10.60.2-0.3-0.9-0.8-0.7-0.10.2-0.50.5-0.5
Time in novel zone, hab. session 20.10.10.9-0.9-0.2-0.3-0.2-0.0-0.00.4-0.1-0.3-0.4-0.30.2-0.1-0.30.00.60.50.50.20.20.5-0.50.4
Total zone transitions, hab. session 20.10.20.60.5-0.0-0.1-0.2-0.4-0.4-0.3-0.2-0.00.60.8-0.3-0.10.20.2-0.5-0.5-0.5-0.3-0.4-0.40.4-0.4
Total locomotion distance, hab. session 20.40.51.20.8-0.7-0.8-0.8-1.1-0.90.1-0.8-0.70.70.6-0.7-0.80.80.8-0.5-0.6-0.6-0.7-1.1-0.60.6-0.7
Locomotion velocity, hab. session 20.40.61.70.9-0.8-0.9-0.9-1.3-0.90.0-0.8-0.80.60.3-0.6-0.90.80.8-0.4-0.5-0.5-0.7-1.3-0.60.6-0.6
Novel to familiar place preference ratio2.02.25.1-1.4-0.9-0.9-1.2-0.9-1.62.3-1.3-1.01.50.9-1.7-1.31.61.5-1.8-1.8-1.7-1.7-0.6-1.81.8-1.7
Novelty place preference1.11.23.0-1.0-0.6-0.6-0.8-0.7-1.21.7-0.9-0.71.10.6-1.3-0.91.21.1-1.4-1.3-1.3-1.2-0.4-1.41.4-1.3
Time in novel zone, NPP test1.01.03.1-1.3-0.5-0.5-0.7-0.5-1.01.8-0.8-0.61.00.6-1.2-0.81.00.9-1.3-1.2-1.2-1.1-0.3-1.31.3-1.2
Total zone transitions, NPP test0.50.61.7-0.1-1.2-1.3-1.1-1.2-0.90.5-1.0-1.30.40.3-0.8-1.10.60.9-0.0-0.3-0.3-0.7-1.1-0.30.3-0.4
Total locomotion distance, NPP test0.60.92.60.3-1.3-1.3-1.3-1.6-1.00.4-1.2-1.30.60.3-0.9-1.20.81.1-0.1-0.4-0.5-0.8-1.4-0.50.5-0.5
Locomotion velocity, NPP test1.01.53.90.5-1.6-1.6-1.6-2.0-1.30.5-1.5-1.60.80.4-1.1-1.51.21.4-0.3-0.6-0.7-1.1-1.7-0.70.7-0.7
Intraocular pressure0.40.51.5-1.0-0.5-0.7-0.6-0.4-0.81.2-0.7-0.50.5-0.0-0.7-0.80.90.8-0.9-0.7-0.7-0.8-0.4-0.80.8-0.9
Delta distance traveled before/after self-admin1.41.52.5-0.9-1.2-1.3-1.3-0.7-1.31.4-1.3-1.21.21.2-1.3-1.31.61.3-1.1-1.2-1.3-1.3-0.8-1.21.3-1.3
Delta ambulatory time before/after self-admin0.91.22.6-1.2-1.0-1.1-1.1-0.6-1.11.6-1.1-1.00.90.8-1.1-1.21.31.2-1.0-1.0-1.1-1.2-0.5-1.11.1-1.1
Parametrial fat weight0.00.10.90.90.10.10.1-0.40.1-0.50.10.1-0.20.00.40.10.4-0.20.30.20.20.2-0.40.3-0.20.3
Pavlov. Cond. lever latency0.91.23.4-0.11.71.31.51.81.2-0.51.41.6-0.6-0.31.11.5-0.9-1.3-0.10.40.50.91.60.5-0.50.3
Pavlov. Cond. magazine entry latency0.30.41.7-1.30.60.80.60.60.50.30.60.6-0.4-0.20.60.5-0.7-0.50.40.40.40.51.00.3-0.30.5
Pavlov. Cond. change in total contacts0.00.10.2-0.1-0.20.1-0.1-0.50.2-0.1-0.0-0.2-0.2-0.30.1-0.0-0.2-0.00.50.30.30.1-0.10.2-0.20.4
Pavlov. Cond. index score0.10.20.6-0.5-0.7-0.4-0.6-0.8-0.50.4-0.6-0.60.20.1-0.4-0.60.20.50.2-0.1-0.1-0.4-0.5-0.20.20.1
Pavlov. Cond. latency score0.20.30.8-0.6-0.7-0.5-0.7-0.9-0.50.5-0.6-0.70.2-0.0-0.4-0.70.20.60.2-0.1-0.1-0.4-0.6-0.20.20.0
Pavlov. Cond. lever contacts0.70.82.60.0-1.4-1.0-1.3-1.6-0.90.5-1.2-1.30.40.1-0.8-1.20.71.00.2-0.3-0.3-0.8-1.4-0.40.4-0.2
Pavlov. Cond. magazine entry number0.40.52.41.6-0.6-0.8-0.6-0.4-0.5-0.3-0.6-0.60.60.5-0.6-0.51.00.6-0.6-0.6-0.6-0.6-0.8-0.50.5-0.7
Pavlov. Cond. intertrial magazine entries1.51.84.4-1.1-0.8-0.9-1.1-0.6-1.32.1-1.2-0.81.30.7-1.4-1.31.61.4-1.6-1.6-1.5-1.6-0.8-1.71.7-1.6
Pavlov. Cond. lever-magazine prob. diff.0.30.30.9-0.5-0.8-0.5-0.8-0.9-0.70.6-0.7-0.80.40.2-0.6-0.80.40.70.0-0.3-0.3-0.5-0.6-0.40.4-0.1
Pavlov. Cond. response bias0.00.10.3-0.4-0.30.1-0.2-0.4-0.10.0-0.2-0.3-0.00.00.0-0.2-0.20.10.50.20.20.1-0.10.2-0.20.4
Pavlov. Cond. lever latency0.91.22.91.5-0.3-0.30.20.10.6-1.50.4-0.2-1.4-1.40.90.4-0.8-0.61.71.61.51.1-0.01.6-1.61.3
Pavlov. Cond. magazine entry latency0.70.92.1-0.81.41.20.81.20.00.50.61.30.91.5-0.00.80.0-0.4-1.3-1.1-1.0-0.31.0-1.00.9-0.8
Pavlov. Cond. change in total contacts0.61.02.9-1.20.50.50.00.3-0.41.2-0.20.51.31.3-0.7-0.10.70.4-1.7-1.6-1.5-1.00.2-1.51.5-1.3
Pavlov. Cond. index score0.91.23.3-1.41.00.90.40.7-0.31.20.21.01.31.7-0.50.30.50.1-1.8-1.6-1.5-0.80.7-1.51.5-1.3
Pavlov. Cond. latency score0.81.13.2-1.21.00.90.30.6-0.31.10.10.91.31.7-0.50.20.50.2-1.8-1.6-1.5-0.80.5-1.51.5-1.2
Pavlov. Cond. lever contacts0.60.92.2-1.20.30.3-0.20.0-0.41.2-0.30.31.21.4-0.7-0.20.70.5-1.5-1.4-1.3-0.90.1-1.41.3-1.1
Pavlov. Cond. magazine entry number0.81.03.50.8-1.9-1.7-1.4-1.5-0.6-0.2-1.2-1.8-0.3-0.8-0.5-1.30.50.91.00.70.6-0.2-1.30.5-0.50.4
Pavlov. Cond. intertrial magazine entries0.60.84.0-0.5-0.10.10.20.40.9-0.00.4-0.1-1.4-2.00.80.1-0.8-0.41.51.31.30.80.11.1-1.11.2
Pavlov. Cond. lever-magazine prob. diff.1.01.43.8-1.41.11.00.40.8-0.41.20.21.01.41.8-0.50.30.50.1-1.9-1.7-1.6-0.80.8-1.61.6-1.3
Pavlov. Cond. response bias0.60.81.9-1.40.90.80.40.6-0.00.90.20.91.01.2-0.30.30.20.0-1.4-1.2-1.2-0.60.7-1.21.1-0.9
Time in closed arm before self-admin0.50.61.30.50.60.70.70.90.8-0.40.70.7-1.1-1.10.80.6-0.6-0.71.00.90.90.80.40.8-0.81.0
Time in closed arm after self-admin0.30.30.6-0.10.30.30.40.80.6-0.10.50.4-0.6-0.30.60.5-0.3-0.50.70.70.60.60.80.7-0.70.7
Time in open arm before self-admin0.40.42.0-0.6-0.0-0.2-0.2-0.7-0.30.2-0.2-0.00.91.4-0.4-0.20.20.3-1.2-0.8-0.7-0.5-0.3-0.70.7-1.0
Time in open arm after self-admin0.91.01.5-0.3-0.8-0.7-0.9-1.1-1.00.8-1.0-0.91.10.8-1.1-0.91.21.1-1.1-1.2-1.2-1.1-0.6-1.11.2-1.1
Bone: periosteal estimation0.40.82.41.5-0.7-0.9-0.8-1.0-0.9-0.6-0.8-0.81.11.6-0.9-0.50.80.7-0.7-0.8-0.9-0.7-0.6-0.60.6-0.8
Bone: periosteal perimeter0.20.31.60.5-0.2-0.3-0.3-0.6-0.6-0.1-0.4-0.30.81.3-0.6-0.20.40.4-0.8-0.7-0.7-0.5-0.2-0.60.6-0.7
Bone: post-yield work0.00.10.50.20.40.20.20.4-0.0-0.30.20.20.20.70.10.3-0.3-0.2-0.1-0.1-0.10.10.40.0-0.00.0
Progressive ratio test 1 active lever presses0.30.41.0-0.7-1.0-0.7-0.9-0.6-0.70.8-0.9-1.00.4-0.2-0.9-0.90.30.8-0.0-0.3-0.3-0.6-0.4-0.40.4-0.2
Progressive ratio test 1 breakpoint0.30.41.0-0.5-1.0-0.7-0.9-0.6-0.70.7-0.9-1.00.4-0.2-0.9-0.80.30.80.0-0.3-0.3-0.6-0.5-0.40.4-0.2
Progressive ratio test 1 inactive lever presses0.10.20.60.4-0.8-0.5-0.6-0.6-0.4-0.1-0.6-0.70.40.1-0.6-0.50.20.50.1-0.2-0.2-0.3-0.3-0.20.1-0.0
Progressive ratio test 2 active lever presses0.20.20.9-0.0-1.0-0.4-0.6-0.6-0.50.5-0.6-0.80.2-0.4-0.8-0.60.30.60.1-0.2-0.2-0.4-0.2-0.20.2-0.0
Progressive ratio test 2 breakpoint0.20.21.00.1-1.0-0.4-0.6-0.6-0.40.4-0.6-0.80.1-0.5-0.7-0.60.30.50.3-0.0-0.1-0.3-0.2-0.10.10.1
Progressive ratio test 2 inactive lever presses0.00.10.6-0.3-0.40.1-0.2-0.2-0.00.4-0.2-0.3-0.0-0.8-0.3-0.2-0.00.2-0.0-0.1-0.1-0.2-0.0-0.20.2-0.0
Incentive Sensitization - Responses0.00.10.4-0.6-0.20.10.00.00.00.60.0-0.1-0.2-0.6-0.1-0.10.10.00.10.10.1-0.00.30.0-0.00.1
Incentive Sensitization - Breakpoint0.00.10.4-0.5-0.3-0.0-0.0-0.0-0.00.6-0.0-0.1-0.2-0.5-0.2-0.10.20.10.10.10.0-0.10.3-0.00.00.0
Sum of active levers in priming session hrs 5-60.20.20.60.7-0.4-0.3-0.3-0.70.0-0.7-0.2-0.5-0.20.1-0.1-0.2-0.50.10.70.40.40.2-0.70.4-0.40.5
Progressive ratio0.30.51.3-0.1-0.6-0.6-0.7-1.0-0.80.9-0.7-0.60.3-0.3-0.6-0.90.60.8-0.6-0.6-0.5-0.8-1.1-0.80.8-0.7
Food seeking constrained by brief footshock2.83.45.00.71.92.12.12.11.8-1.92.02.0-1.5-1.02.02.2-1.9-2.11.51.61.52.02.21.8-1.81.8
Seeking ratio, punishment vs. effort2.94.16.50.72.12.12.22.32.1-2.52.22.1-1.4-0.22.12.5-2.0-2.41.71.71.62.32.62.1-2.11.9
Retroperitoneal fat weight0.10.31.1-0.90.60.40.60.80.40.60.60.5-0.8-1.00.50.4-0.3-0.50.20.50.50.41.00.4-0.40.3
Reaction time number correct0.10.30.70.8-0.2-0.30.10.10.5-0.70.2-0.1-0.5-0.40.40.2-0.2-0.30.80.80.70.60.20.8-0.80.5
Reaction time mean minus median0.51.39.5-3.10.60.60.20.6-0.32.00.00.50.90.5-0.6-0.00.10.3-1.7-1.4-1.2-0.80.7-1.41.4-1.2
Reaction time mean minus median AUC0.30.75.7-2.40.60.60.30.5-0.11.40.10.50.70.6-0.40.1-0.00.1-1.3-1.0-0.9-0.60.6-1.01.0-0.8
Reaction time num false alarms1.52.23.4-0.5-0.9-0.9-1.2-1.3-1.61.3-1.3-1.01.61.3-1.5-1.41.61.5-1.8-1.8-1.7-1.7-1.5-1.81.8-1.7
Reaction time num false alarms AUC2.33.65.3-0.7-1.3-1.3-1.7-1.7-2.11.6-1.8-1.42.21.8-2.0-1.82.01.9-2.2-2.3-2.2-2.2-1.9-2.32.3-2.2
Reaction time trials correct on left0.10.30.70.8-0.2-0.30.10.10.5-0.70.2-0.1-0.5-0.40.40.2-0.2-0.30.80.80.70.60.20.8-0.80.5
Reaction time trials on left0.10.20.50.7-0.2-0.30.10.20.5-0.60.1-0.1-0.5-0.40.30.2-0.2-0.30.70.70.60.50.20.7-0.70.4
Reaction time mean0.61.09.4-3.10.80.90.50.80.22.10.30.70.1-0.6-0.20.1-0.20.0-1.1-0.8-0.6-0.50.9-1.01.0-0.6
Reaction time mean AUC0.50.87.3-2.71.01.00.70.90.51.60.50.8-0.1-0.80.10.4-0.5-0.2-0.7-0.4-0.3-0.21.0-0.60.6-0.3
Median of all reaction times0.60.87.5-2.70.90.90.60.90.51.80.50.7-0.3-1.10.20.2-0.4-0.2-0.6-0.3-0.2-0.20.9-0.60.5-0.2
Reaction time omissions1.21.76.6-2.60.00.0-0.30.0-0.82.3-0.6-0.01.20.3-1.1-0.60.60.9-2.2-1.8-1.6-1.4-0.0-1.91.9-1.8
Reaction time false alarm rate2.94.06.4-1.0-1.2-1.2-1.7-1.7-2.31.8-1.8-1.32.32.0-2.1-1.82.02.0-2.4-2.5-2.4-2.3-1.9-2.52.5-2.3
Reaction time premature initiation rate0.10.20.8-0.20.50.90.40.80.00.20.20.40.4-0.00.00.40.2-0.2-0.3-0.5-0.6-0.10.9-0.40.40.1
Reaction time premature initiations0.10.21.10.30.50.80.51.00.4-0.30.40.4-0.1-0.40.30.6-0.0-0.40.20.1-0.10.31.00.2-0.20.4
Std. dev. reaction times0.81.47.9-2.80.40.50.00.4-0.52.1-0.20.31.10.6-0.8-0.20.40.5-1.9-1.6-1.4-1.10.6-1.71.6-1.4
Reaction time trials completed0.10.20.50.7-0.2-0.30.10.20.5-0.60.1-0.1-0.5-0.40.30.2-0.2-0.30.70.70.60.50.20.7-0.70.4
Reaction time trials AUC0.10.10.50.7-0.4-0.5-0.1-0.00.3-0.5-0.1-0.3-0.3-0.20.10.00.1-0.10.50.40.40.30.00.5-0.50.2
Run reversals in cocaine runway, females0.30.33.1-1.80.50.60.40.40.21.20.30.4-0.2-0.10.10.1-0.2-0.1-0.4-0.2-0.1-0.10.4-0.30.3-0.2
Run reversals in cocaine runway, males3.23.29.1-3.0-1.3-1.4-1.6-1.3-1.72.0-1.6-1.41.91.6-1.7-1.61.21.7-2.1-1.9-1.8-1.9-1.5-2.01.9-2.1
Latency to leave start box in cocaine runway0.40.41.2-0.2-1.0-1.1-1.0-0.8-0.60.4-0.9-1.00.30.6-0.7-0.90.40.80.3-0.1-0.1-0.5-0.9-0.20.1-0.1
Latency to leave start box in cocaine runway, F0.70.82.2-0.2-1.4-1.4-1.3-1.4-0.80.5-1.2-1.30.30.3-0.9-1.30.41.00.4-0.00.0-0.6-1.5-0.20.2-0.1
Latency to leave start box in cocaine runway, M0.10.10.5-0.50.30.20.20.60.10.10.10.20.30.40.10.20.1-0.1-0.7-0.4-0.4-0.10.6-0.30.3-0.5
Std. dev. time between licks in bursts1.62.13.7-1.51.81.81.81.91.7-0.11.71.9-1.3-1.51.61.6-1.6-1.60.61.01.11.31.70.9-1.01.0
Total sessions with >9 infusions0.20.33.4-1.90.10.30.20.50.10.80.10.10.0-0.5-0.00.1-0.5-0.0-0.3-0.2-0.1-0.10.7-0.30.2-0.2
Short access day 1 total inactive lever presses1.21.52.7-0.3-1.6-1.5-1.5-1.6-1.41.4-1.4-1.50.90.1-1.5-1.61.11.4-0.6-0.8-0.8-1.3-1.4-1.01.0-0.9
Short access day 10 total inactive lever presses0.30.76.12.5-0.6-0.6-0.6-1.0-0.5-0.9-0.6-0.50.71.0-0.4-0.41.10.5-0.5-0.6-0.6-0.5-1.0-0.40.5-0.6
Short access day 1 total infusions0.10.11.4-1.2-0.2-0.0-0.0-0.10.10.80.0-0.1-0.2-0.9-0.0-0.2-0.50.00.20.20.30.00.20.0-0.10.1
Short access day 10 total infusions0.20.21.10.2-0.5-0.2-0.3-0.20.00.1-0.2-0.4-0.5-1.0-0.1-0.2-0.20.10.90.50.50.20.00.4-0.40.7
Short access total infusions0.10.21.5-1.20.10.30.20.40.30.60.20.2-0.3-0.90.20.1-0.6-0.20.10.20.30.20.60.1-0.10.2
Short access day 1 locomotion1.01.31.8-1.1-1.1-0.8-1.0-0.7-1.11.4-1.1-1.11.30.7-1.3-1.01.01.2-1.2-1.3-1.3-1.3-0.3-1.31.3-1.2
Short access day 10 total locomotion0.30.50.9-0.3-0.8-0.8-0.9-0.7-0.80.8-0.9-0.90.50.3-0.7-0.90.90.9-0.3-0.5-0.6-0.8-0.7-0.60.6-0.5
Short access total locomotion0.10.10.2-0.30.20.30.30.50.3-0.10.20.2-0.3-0.30.30.3-0.4-0.30.30.30.30.30.50.3-0.30.4
One hour access (0.3 mA shock)0.10.10.6-0.20.30.60.40.60.3-0.10.30.3-0.2-0.40.00.4-0.2-0.30.00.10.00.20.80.1-0.10.2
Compulsive drug intake0.80.91.30.71.00.70.91.10.8-1.11.00.9-1.0-0.30.81.0-0.9-1.11.01.11.01.10.91.1-1.11.0
One hour access (shock baseline)0.71.11.6-0.6-1.3-0.9-1.2-1.0-1.01.2-1.2-1.21.00.2-1.2-1.21.11.2-0.9-1.1-1.1-1.2-0.8-1.21.2-1.0
Social response proportion0.20.21.4-1.20.50.80.50.70.40.60.40.5-0.1-0.50.20.4-0.5-0.3-0.1-0.1-0.10.10.8-0.10.10.2
Social responses0.91.22.5-1.01.41.61.41.51.3-0.21.31.4-0.8-0.91.11.3-1.2-1.20.40.60.60.91.40.6-0.60.7
Social time0.20.30.6-0.5-0.2-0.2-0.3-0.1-0.50.6-0.4-0.20.7-0.1-0.5-0.40.40.4-0.7-0.7-0.7-0.6-0.5-0.70.7-0.6
Soleus weight2.36.711.30.9-3.2-3.4-3.1-3.2-2.61.4-3.0-3.12.32.0-2.7-3.02.72.9-1.8-2.1-2.1-2.6-2.9-2.12.1-2.4
Bone: stiffness0.00.00.1-0.10.10.00.1-0.00.00.10.10.10.20.3-0.10.1-0.2-0.0-0.4-0.2-0.1-0.00.2-0.10.1-0.2
Tibialis anterior weight2.06.715.72.0-4.0-4.0-3.5-3.6-2.60.2-3.3-3.91.61.0-2.5-3.32.42.9-0.4-1.0-1.1-2.2-3.8-1.11.1-1.5
Time to tail flick, vehicle, before self-admin1.31.43.0-1.2-1.5-1.7-1.5-1.6-1.41.4-1.4-1.50.70.8-1.3-1.60.91.3-0.1-0.5-0.5-1.0-1.4-0.70.6-0.6
Time to tail flick, vehicle, after self-admin0.50.63.0-1.2-0.8-1.1-0.9-0.7-0.81.7-0.7-0.9-0.3-0.9-0.6-1.10.50.80.30.20.3-0.5-0.9-0.20.1-0.0
Time to tail flick, test, before self-admin1.31.34.01.0-1.8-2.0-1.7-1.2-1.31.1-1.5-1.8-0.1-0.2-1.0-1.61.41.21.20.40.2-0.6-1.00.2-0.10.4
Time to tail flick, test, after self-admin0.70.81.81.0-1.3-1.3-1.2-1.3-0.90.7-1.0-1.10.2-0.3-0.9-1.21.00.90.2-0.1-0.1-0.7-1.3-0.30.3-0.2
Delta time to tail flick, vehicle, before/after SA0.10.10.40.3-0.1-0.2-0.2-0.3-0.10.3-0.1-0.1-0.2-0.5-0.1-0.30.20.10.20.20.2-0.1-0.60.0-0.00.1
Delta time to tail flick, test, before/after SA0.20.21.1-0.60.30.50.3-0.10.10.10.20.40.40.1-0.00.2-0.2-0.1-1.0-0.6-0.4-0.3-0.3-0.60.6-0.7
Tibia length0.20.51.7-1.3-0.7-0.4-0.8-0.5-0.71.2-0.7-0.70.70.4-0.7-0.80.80.8-0.4-0.6-0.6-0.7-0.3-0.70.7-0.4
Ambulatory time before self-admin0.50.78.32.9-0.3-0.3-0.3-1.0-0.2-1.9-0.2-0.30.40.9-0.20.00.2-0.00.20.0-0.10.1-1.20.2-0.20.0
Ambulatory time after self-admin0.60.72.71.6-0.9-1.0-0.9-1.1-0.8-0.4-0.9-0.90.71.1-0.8-0.71.10.7-0.2-0.5-0.6-0.6-1.1-0.30.4-0.4
Bone: tissue strength0.40.51.20.91.11.10.80.90.3-0.80.81.00.10.70.50.9-0.1-0.7-0.2-0.1-0.20.40.90.1-0.00.1
Total heroin consumption0.60.75.5-2.30.60.70.60.60.81.00.60.5-0.8-0.90.60.4-1.3-0.50.30.60.70.50.90.4-0.40.5
Bone: trabecular number0.71.13.11.41.11.11.11.11.4-1.81.11.2-0.60.31.11.3-1.0-1.20.50.70.61.11.00.9-0.90.8
Bone: trabecular spacing1.01.43.0-1.3-1.5-1.6-1.4-1.7-1.21.7-1.3-1.40.3-0.6-1.0-1.60.81.3-0.4-0.4-0.3-1.1-1.6-0.70.7-0.8
Bone: trabecular thickness0.40.51.71.21.01.20.80.60.8-1.30.80.9-0.00.60.50.9-0.5-0.7-0.10.10.00.50.60.2-0.20.4
Bone: trabecular tissue density0.40.61.40.90.30.60.6-0.10.8-0.90.60.4-1.0-1.20.80.5-0.5-0.71.01.00.90.8-0.20.9-0.91.0
Water consumed over 24 hours1.21.66.61.0-0.8-0.9-1.1-0.7-1.2-0.2-1.1-0.91.92.6-1.2-0.81.21.1-1.4-1.5-1.6-1.2-0.6-1.21.3-1.3
Number of responses in last shaping day2.42.63.9-0.4-1.7-1.7-1.8-1.7-1.71.4-1.8-1.71.71.1-2.0-1.71.71.8-1.4-1.6-1.5-1.7-1.6-1.61.6-1.6